Publication Date:
1995-11-17
Description:
To analyze the rules that govern communication between eye and brain, visual responses were recorded from an intact salamander retina. Parallel observation of many retinal ganglion cells with a microelectrode array showed that nearby neurons often fired synchronously, with spike delays of less than 10 milliseconds. The frequency of such synchronous spikes exceeded the correlation expected from a shared visual stimulus up to 20-fold. Synchronous firing persisted under a variety of visual stimuli and accounted for the majority of action potentials recorded. Analysis of receptive fields showed that concerted spikes encoded information not carried by individual cells; they may represent symbols in a multineuronal code for vision.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meister, M -- Lagnado, L -- Baylor, D A -- EY01543/EY/NEI NIH HHS/ -- EY05750/EY/NEI NIH HHS/ -- EY10020/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1995 Nov 17;270(5239):1207-10.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7502047" target="_blank"〉PubMed〈/a〉
Keywords:
Action Potentials
;
Animals
;
In Vitro Techniques
;
Microelectrodes
;
Photic Stimulation
;
Retinal Ganglion Cells/*physiology
;
Signal Transduction
;
Urodela
;
Vision, Ocular/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
