Publication Date:
1992-06-19
Description:
The relation of cellular activity in the motor cortex to the direction of two-dimensional isometric force was investigated under dynamic conditions in monkeys. A task was designed so that three force variables were dissociated: the force exerted by the subject, the net force, and the change in force. Recordings of neuronal activity in the motor cortex revealed that the activity of single cells was directionally tuned and that this tuning was invariant across different directions of a bias force. Cell activity was not related to the direction of force exerted by the subject, which changed drastically as the bias force changed. In contrast, the direction of net force, the direction of force change, and the visually instructed direction all remained quite invariant and congruent and could be the directional variables, alone or in combination, to which cell activity might relate.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Georgopoulos, A P -- Ashe, J -- Smyrnis, N -- Taira, M -- NS07226/NS/NINDS NIH HHS/ -- NS17413/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1992 Jun 19;256(5064):1692-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Brain Sciences Center, Department of Veterans Affairs Medical Center, Minneapolis, MN 55455.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1609282" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Electrophysiology
;
Haplorhini
;
Isometric Contraction/*physiology
;
Motor Activity/physiology
;
Motor Cortex/*physiology
;
Motor Neurons/physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
