ISSN:
1432-1432
Keywords:
CpG shortage
;
Methylation
;
Genome organization
;
Schistosoma mansoni
;
Platyhelminths
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract We report the analysis of the biases of CpG, TpG, and CpA of all the DNA sequences data from the Trematode Schistosoma mansoni. Our results show CpG avoidance whereas TpG and CpA frequencies are over the expected values. These characteristics are similar to the biases displayed by methylated genomes, but in platyhelminths 5mC has not been detected by biochemical methods. The possible implications of this CpG shortage are discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00175493