ISSN:
1573-1561
Keywords:
Growth-inhibitory agents
;
insecticides
;
pink bollworm
;
Pectinophora gossypiella
;
Gelechiidae
;
Lepidoptera
;
diterpene esters
;
croton oil
;
Croton tiglium
;
Euphorbiaceae
;
12-O-tetradecanoylphorbol-13-acetate
;
12-O-(2-methyl)butyrylphorbol-13-decanoate
;
daphnetoxin
;
ingenol esters
;
ingol esters
;
mortality
;
house mosquito
;
Culex pipiens
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract Twenty esters, representing the biogenetically related tigliane, daphnane, ingenane, and lathyrane series of diterpenes, were screened for growth-inhibitory and insecticidal effects on newly hatched larvae of the North American cotton pest,Pectinophora gossypiella (pink bollworm). Among the tigliane derivatives tested, only 12-O-tetradecanoylphorbol-13-acetate and 12-O-(2-methyl)butyrylphorbol-13-decanoate, of seven phorbol diesters isolated from croton oil by a new procedure involving droplet countercurrent chromatography, were active againstP.gossypiella as both growth inhibitors and insecticides. The effects of the former compound were not significantly diminished by acetylation of its C-20 primary hydroxy group. Three other croton oil phorbol diester constituents, as well as daphnetoxin and daphnetoxin-5,20-diacetate, exhibited activity as growth inhibitors, but not as insecticidal agents, at the doses used. None of the ingenane or lathyrane derivatives investigated was active in either respect. 12-0-Tetradecanoylphorbol-13-acetate was found to cause 100% mortality on second-stadium larvae ofCulex pipiens at 0.6 ppm, but exhibited less significant effects onOncopeltus fasciatus (second-stadium nymphs) andTribolium confusion (adults) when applied at higher doses.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00988202
