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  • Books  (354)
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  • Chemistry and Pharmacology  (234)
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  • 1
    Unknown
    The Gene Ontology Handbook (2017)
    New York, NY : Humana Press
    Details
    Keywords: Life sciences ; Bioinformatics ; Life Sciences ; Bioinformatics
    Description / Table of Contents: Primer on Ontologies --- The Gene Ontology and the Meaning of Biological Function --- Primer on the Gene Ontology --- Best Practices in Manual Annotation with the Gene Ontology --- Computational Methods for Annotation Transfers from Sequence --- Text Mining to Support Gene Ontology Curation and Vice Versa --- How Does the Scientific Community Contribute to Gene Ontology? --- Evaluating Computational Gene Ontology Annotations --- Evaluating Functional Annotations of Enzymes Using the Gene Ontology --- Community-Based Evaluation of Computational Function Prediction --- Get GO!: Retrieving GO Data Using AmiGO, QuickGO, API, Files, and Tools --- Semantic Similarity in the Gene Ontology --- Gene-Category Analysis --- Gene Ontology: Pitfalls, Biases, and Remedies --- Visualizing GO Annotations --- A Gene Ontology Tutorial in Python --- Annotation Extensions --- The Evidence and Conclusion Ontology (ECO): Supporting GO Annotations --- Complementary Sources of Protein Functional Information: The Far Side of GO --- Integrating Bio-Ontologies and Controlled Clinical Terminologies: From Base Pairs to Bedside Phenotypes --- The Vision and Challenges of the Gene Ontology
    Pages: Online-Ressource (XII, 305 pages) , 56 illustrations, 50 illustrations in color
    ISBN: 9781493937431
    URL: https://link.springer.com/openurl?genre=book&isbn=978-1-4939-3743-1
    Language: English
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  • 2
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    Fundamentals for the Anthropocene (2017)
    Warsaw, Berlin : De Gruyter Open
    Details
    Keywords: anthropocene ; non equilibrium thermodynamics ; life structure
    Description / Table of Contents: Introduction --- 1 The Visible Universe Starts With – Believe It or Not – Correlation --- 2 Correlation=Differentiation=Order --- 3 Some Basic Characteristics of this Ordering Process as Thus Conceived --- 4 Hierarchy and Emergence Theories --- 5 Causation --- 6 The Arrow of Time --- 7 Complexity --- 8 Life --- 9 Energy --- 10 Globalization (Make It or Break It) --- 11 Ethics, Thermodynamics, and The Anthropocene --- Appendix A: Note on Ontology and Epistemology --- Appendix B: A Selection of Human Social Conventions Which Favor Cooperative, and Thus Correlated, or Coordinated, Behavior --- Appendix C: Quantitative Wikis For Energy Supply and Distribution Modeling
    Pages: Online-Ressource (VI, 130 Seiten)
    ISBN: 9783110567304
    URL: https://www.degruyter.com/viewbooktoc/product/496571
    Language: English
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  • 3
    Unknown
    Functional morphology of mitochondrion-rich cells in euryhaline and stenohaline teleosts (2008)
    Tokyo : TERRAPUB
    Details
    Keywords: mitochondrion-rich cell ; chloride cell ; euryhalinity ; stenohalinity ; diadromous migration ; Mozambique tilapia ; killifish ; chum salmon ; Japanese eel ; fugu ; Japanese dace ; ion transport
    Description / Table of Contents: 1. Introduction --- 2. Mitochondrion-rich (MR) cells --- 2-1. General characteristics of MR cells --- 2-2. Molecular mechanisms of ion-transporting functions of MR cells --- 3. Euryhalinity and stenohalinity of teleosts --- 4. Mozambique tilapia --- 4-1. MR cells in the yolk-sac membrane of tilapia embryos and larvae --- 4-2. FW- and SW-type MR cells in tilapia embryos and larvae --- 4-3. Functions of multicellular complexes of SW-type MR cells --- 4-4. Functional differentiation of MR cells in the yolk-sac membrane --- 4-5. Functional classification of MR cells in the yolk-sac membrane --- 4-6. "Yolk ball" incubation system --- 4-7. Salinity tolerance of adult tilapia --- 4-8. Possible osmoreception by MR cells --- 5. Killifish --- 5-1. Transitional processes of MR-cell distribution during early life stages --- 5-2. Distinct FW- and SW-type MR cells --- 5-3. Functional alteration and replacement of MR cells --- 5-4. Ion-absorbing mechanisms of MR cells --- 6. Chum salmon --- 6.1. Hypoosmoregulatory ability of chum salmon embryo --- 6-2. Seawater adaptability in chum salmon fry --- 6-3. MR-cell turnover in the gills of chum salmon fry --- 6-4. Loss of hypoosmoregulatory ability in mature chum salmon --- 7. Japanese eel --- 7-1. Epidermal MR cells in embryos and larvae --- 7-2. Ontogenic changes in MR cells during leptocephalus and glass eel stages --- 7-3. MR cells in glass eel acclimated to FW --- 7-4. Gill MR cells in eel cultured in FW and those acclimated to SW --- 7-5. MR cells in yellow and silver eel --- 8. Fugu --- 8-1. Low-salinity tolerance of fugu --- 8-2. Gill MR cells in fugu --- 8-3. Functional significance of prolactin in a marine teleost of fugu --- 8-4. Comparison of growth in fugu reared in 25 and 100% SW. --- 9. Japanese dace --- 9-1. Acid tolerance of Osorezan dace --- 9-2. Molecular mechanisms of acid adaptation --- 10. Conclusions and future perspectives
    Pages: Online-Ressource (62 Seiten)
    ISBN: 1882322X
    URL: http://www.terrapub.co.jp/onlinemonographs/absm/abstract/01/0101.html
    Language: English
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  • 4
    Unknown
    Studies on eel liver functions using perfused liver and primary cultured hepatocytes (2008)
    Tokyo : TERRAPUB
    Details
    Keywords: perfused eel livers ; isolated eel hepatocytes ; cultured eel hepatocytes ; gluconeogenesis ; glycogen synthesis ; glucagon ; lipoprotein synthesis ; ganglioside GM4
    Description / Table of Contents: 1. Introduction --- 2. Eel as an experimental fish for studying liver functions --- 2-1. Availability of eel (Anguilla japonica) as an experimental fish --- 2-2. Perfusion of eel liver --- 2-3. Primary culture of eel hepatocytes --- 2-3A. Isolated eel hepatocytes --- 2-3B. Primary culture of eel hepatocytes --- 3. Glucose metabolisms in eel liver --- 3-1. Gluconeogenesis in rat liver --- 3-2. Gluconeogenesis in eel liver --- 3-2A. Gluconeogenesis by perfused eel liver --- 3-2B. Gluconeogenesis by isolated eel hepatocytes and cultured eel hepatocytes --- 3-3. Phosphoenolpyruvate synthesis pathway in eel liver --- 3-3A. Effects of inhibitors --- 3-3B. Subcellular distribution of enzymes --- 3-3C. Effects of leucine and other amino acids --- 3-3D. Effect of oleic acid --- 3-4. Comparison of PEP synthesis pathways between eel, rat, and pigeon liver --- 3-5. Glycogen metabolisms in eel liver --- 4. Lipoprotein metabolisms in eel liver --- 4-1. Characteristics of fish serum lipoproteins --- 4-2. Lipoproteins secreted by primary cultured eel hepatocytes --- 4-3. Effects of maturation on eel lipoprotein metabolism --- 4-3A. Comparison of body length, body weight, gonad-somatic index, and plasma thyroxine between silver and yellow eels --- 4-3B. Comparison of plasma lipoproteins between silver and yellow eels --- 4-3C. Comparison of lipoprotein synthesis by cultured hepatocytes of silver and yellow eels --- 4-3D. Effect of thyroxine on lipoprotein synthesis by cultured eel hepatocytes --- 4-4. HDL binding to primary cultured eel hepatocytes --- 4-4A. Stimulatory effect of HDL on VLDL-like lipoprotein synthesis and secretion --- 4-4B. ApoAI and apoAII of HDL do not function as a ligand for eel HDL receptor --- 4-4C. Ganglioside of HDL functions as a ligand for an HDL receptor of eel hepatocytes --- 4-4C-1. Ganglioside GM4 isolated from eel serum HDL --- 4-4C-2. GM4 as the ligand for eel HDL receptor --- 4-5. Vitellogenin induction by cultured eel hepatocytes --- 4-5A. Vitellogenin induction by estradiol-17β --- 4-5B. Vitellogenin induction by cultured eel hepatocytes --- 4-5C. Stimulatory effect of HDL on vitellogenin synthesis and secretion --- 5. Discussion --- 5-1. Integrity of a perfused eel liver, isolated and cultured hepatocytes --- 5-2. Gluconeogenesis and glycogen metabolisms in eel liver --- 5-2A. Gluconeogenesis --- 5-2B. Glycogen metabolisms --- 5-3. Lipoprotein metabolisms in eel liver --- 5-3A. Lipoprotein synthesized by cultured eel hepatocytes --- 5-3B. HDL metabolism --- 5-3C. Induction of vitellogenin synthesis by cultured eel hepatocytes. --- 5-4. General Discussion
    Pages: Online-Ressource (57 Seiten)
    ISBN: 1882322X
    URL: http://www.terrapub.co.jp/onlinemonographs/absm/abstract/01/0102.html
    Language: English
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  • 5
    Unknown
    Life history and evolution of migration in catadromous eels (Genus Anguilla) (2009)
    Tokyo : TERRAPUB
    Details
    Keywords: Anguilla ; phylogeny ; life history ; migration ; ecology ; evolution
    Description / Table of Contents: 1. Introduction --- 2. Phylogeny of the genus Anguilla --- 2-1. Morphological studies --- 2-2. Molecular phylogenetic approaches --- 2-3. A new species in the genus Anguilla --- 3. Life histories of temperate anguillids --- 3-1. Spawning areas of temperate eels --- 3-2. Larval migration of temperate eels --- 3-3. Growth phase and spawning migration --- 4. Population structure of temperate eels --- 5. Life histories of tropical anguillids --- 5-1. Spawning areas of tropical eels --- 5-2. Larval migration of tropical eels --- 5-3. Growth phase and spawning migration --- 6. Population structure of tropical eels --- 7. Discussion --- 7-1. Evolution of migration in anguillid eels --- 7-2. Management and conservation of eel resources
    Pages: Online-Ressource (42 Seiten)
    ISBN: 1882322X
    URL: http://www.terrapub.co.jp/onlinemonographs/absm/abstract/02/0201.html
    Language: English
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  • 6
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    Behavioral ontogeny of marine pelagic fishes with the implications for the sustainable management of fisheries resources (2009)
    Tokyo : TERRAPUB
    Details
    Keywords: behavioral ontogeny ; schooling ; docosahesaenoic acid ; Pseudocaranx dentex ; Seriola quinqueradiata ; Trachurus japonicus ; jellyfish ; recruitment
    Description / Table of Contents: 1. General introduction --- 2. Morphological development of sensory and swimming organs and the central nervous system in the striped jack --- 2-1. Introduction --- 2-2. Materials and methods --- 2-2A. Materials --- 2-2B. Morphology --- 2-2C. Histology of eye, lateral line, muscle, bone and the central nervous system --- 2-3. Results --- 2-3A. Morphology --- 2-3B. Relative growth --- 2-3C. Ossification --- 2-3D. Muscle --- 2-3E. Eye --- 2-3F. Cephalic and trunk lateral lines --- 2-3G. The central nervous system --- 2-4. Discussion --- 2-4A. Morphological development related to swimming ability --- 2-4B. Development of sensory organs --- 2-4C. Development of the central nervous system --- 3. Ontogeny of schooling behavior and other behavioral traits in the striped jack --- 3-1. Introduction --- 3-2. Materials and methods --- 3-2A. Phototaxis --- 3-2B. Rheotaxis --- 3-2C. Optokinetic response --- 3-2D. Schooling behavior --- 3-2E. Association with floating objects --- 3-3. Results --- 3-3A. Phototaxis --- 3-3B. Rheotaxis --- 3-3C. Optokinetic response --- 3-3D. Schooling behavior --- 3-3E. Association behavior --- 3-4. Discussion --- 3-4A. Development of taxis in relation to sensory and swimming organs --- 3-4B. Ecological speculations on survival strategy and migratory behavior --- 4. Critical involvement of the central nervous system for the development of schooling behavior revealed by docosahexaenoic acid deficiency experiments --- 4-1. Introduction --- 4-2. Materials and methods --- 4-2A. Effect of dietary DHA on the growth, survival, and brain development in the striped jack --- 4-2B. Effect of dietary condition on behavior --- 4-2C. Incorporation of DHA into the central nervous system --- 4-3. Results --- 4-3A. Effect of dietary DHA on the growth, survival, and brain development in the striped jack --- 4-3B. Effect of dietary condition on the schooling behavior of yellowtail --- 4-3C. Incorporation of DHA into the central nervous system in the yellowtail --- 4-4. Discussion --- 5. Ontogeny of association behavior between jack mackerel and jellyfish --- 5-1. Introduction --- 5-2. Materials and methods --- 5-2A. Feeding on jellyfish --- 5-2B. Utilization of jellyfish as a prey collector --- 5-2C. Utilization of jellyfish as a refuge from predators --- 5-2D. Ontogenetic changes in the function of association between jack mackerel and jellyfish --- 5-2E. Underwater observation of fish assemblages associated with jellyfish --- 5-3. Results --- 5-3A. Feeding on jellyfish --- 5-3B. Utilization of jellyfish as a prey collector --- 5-3C. Utilization of jellyfish as a refuge from predators --- 5-3D. Ontogenetic changes of the function of association between jack mackerel and jellyfish --- 5-3E. Underwater observation of fish assemblages associated with jellyfish --- 5-4. Discussion --- 5-4A. Ontogeny of function in the association behavior of jack mackerel with jellyfish --- 5-4B. Ontogeny of mechanisms in associating with jellyfish --- 6. Behavioral ontogeny of common pelagic fishes with reference to the population replacement --- 6-1. Introduction --- 6-2. Materials and methods --- 6-2A. Fish husbandry --- 6-2B. Swimming speed --- 6-2C. Anti-predator performance --- 6-3. Results --- 6-3A. Growth --- 6-3B. Swimming speed and anti-predator performance --- 6-4. Discussion --- 6-4A. Growth performance of hatchery-reared pelagic fish larvae and comparison to wild conspecifics --- 6-4B. Swimming speeds in the context of feeding ecology --- 6-4C. Inter-specific difference of the ontogeny of anti-predator performance --- 6-4D. Environmental factors as a driving force of population replacement --- 7. General discussion: Towards the sustainable management of fisheries resources --- 7-1. Implications of ontogenetic study for the fisheries resource management --- 7-2. Perspectives for the sustainable management in fisheries resources
    Pages: Online-Ressource (56 Seiten)
    ISBN: 1882322X
    URL: http://www.terrapub.co.jp/onlinemonographs/absm/abstract/02/0202.html
    Language: English
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  • 7
    Unknown
    Anthracycline Chemistry and Biology II : Mode of Action, Clinical Aspects and New Drugs (2008)
    Berlin, Heidelberg : Springer
    Details
    Keywords: Biochemistry ; Chemistry ; Chemistry, Organic
    ISBN: 9783540758136
    URL: https://doi.org/10.1007/978-3-540-75813-6
    Language: English
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  • 8
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    Chemistry and Safety of Acrylamide in Food (2005)
    Boston, MA : Springer
    Details
    Keywords: Chemistry ; Food science
    ISBN: 9780387249803
    URL: https://doi.org/10.1007/b106417
    Language: English
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  • 9
    Unknown
    Advances in Food Mycology (2006)
    Boston, MA : Springer
    Details
    Keywords: Chemistry ; Food science ; Immunology
    ISBN: 9780387283913
    URL: https://doi.org/10.1007/0-387-28391-9
    Language: English
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  • 10
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    Advanced Organic Chemistry, Part B : Reactions and Synthesis (2007)
    Boston, MA : Springer
    Details
    Keywords: Biochemistry ; Chemistry, Organic
    Description / Table of Contents: Advanced Organic Chemistry has maintained its place as the premier textbook in the field, since its first appearance in 1977. It offers broad coverage of the structure, reactivity and synthesis of organic compounds. As in the earlier editions, the text contains extensive references to both the primary and review literature and provides examples of data and reactions that illustrate and document the generalizations. While the text assumes completion of an introductory course in organic chemistry, it reviews the fundamental concepts for each topic. This two-part, fifth edition has been substantially revised and reorganized for greater clarity. The control of reactivity to achieve specific syntheses is one of the overarching goals of organic chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. It can stand-alone; together, with Part A: Structure and Mechanisms, the two volumes provide a comprehensive foundation for the study in organic chemistry.
    Pages: Online-Ressource (XXX, 1322 Seiten)
    Edition: 5th ed.
    ISBN: 9780387714813
    URL: http://www.springerlink.com/content/978-0-387-68350-8/
    Language: English
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