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  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences  (402)
  • MDPI - Multidisciplinary Digital Publishing Institute  (402)
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  • Englisch  (402)
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Schlagwort(e): QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 2
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Recombinant viruses expressing reporter fluorescent or bioluminescent proteins are an excellent option to evaluate the dynamics of viral infection progression in both cultured cells and/or validated animal models of viral infection. Reporter proteins are valid surrogates for direct detection of infected cells in vitro and in vivo, without the use of secondary methodologies to identify infected cells. By eliminating the need of secondary labeling, tractable replicating-competent, reporter-expressing viruses provide an ideal approach to monitor viral infections in real time, representing a significant advance in the study of the biology of viruses, to evaluate vaccination approaches, and to identify new therapeutics against viral infections using high-throughput screening settings. In this Special Issue “Replication-Competent Reporter-Expressing Viruses” we review replication-competent, reporter-expressing viruses belonging to different families, methods of characterization, and applications to facilitate the study of in vitro and in vivo viral infections. We also seek to discuss disadvantages and limitations associated with these reporter-expressing viruses. Finally, we provide rational future perspectives and additional avenues for the development, characterization, and applications of recombinant, reporter-expressing, competent viruses.
    Schlagwort(e): QH301-705.5 ; luminescence ; virus rescue approaches ; fluorescence ; Recombinant viruses ; plasmid-based reverse genetics ; reporter genes ; replicating-competent reporter-expressing viruses ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Introducing “A Feasible Approach for Natural Products to Treatment of Diseases”–an exploration of the therapeutic potential locked within nature’s abundant offerings. This comprehensive reprint delves into the fascinating realm of natural products, uncovering their inherent properties, mechanisms of action, and potential roles in effective disease management. Through extensive scientific research and reviews, the authors shed light on the immense potential of natural products as a viable approach to enhancing health and combating diseases. This reprint presents a diverse and multidimensional exploration, bridging the gap between traditional wisdom and contemporary scientific understanding and offering new avenues for healthcare professionals, researchers, and enthusiasts to harness the power of nature’s remarkable resources. As a catalyst for unlocking the healing potential of natural products, this reprint inspires further investigation and innovation, and drives us towards a future where their integration into mainstream healthcare becomes indispensable. Discover the possibilities and embark on a health and well-being journey with “A Feasible Approach for Natural Products to Treatment of Diseases”.
    Schlagwort(e): cancer immunotherapy ; fructan ; FT-IR ; mass spectrometry ; young green barley ; COVID-19 ; β-glucans ; immunomodulation ; anti-inflammation ; anti-oxidant ; ACE2 regulation ; impedance ; ECIS ; antitumor activity ; anticancer properties ; betulin ; betulinic acid ; Amadori rearrangement compounds ; barley ; anti-obesity ; arginyl-fructose ; adipogenic ; ergosta-5,7,22,24(28)-tetraenol (ERGT) ; cholesta-5,7,22,24-tetraenol (CHT) ; ergosterol biosynthesis ; antimetabolite ; suicide substrate ; Trypanosoma brucei ; coronavirus SARS-CoV-2 ; main protease ; Saussurea costus ; molecular docking ; GC-MS profiling ; Molineria recurvata ; diabetic nephropathy ; urinary biomarkers ; inflammation ; oxidative stress ; walnut ; Juglans regia ; high-fat diet ; insulin resistance ; cognitive function ; JNK/NFκB pathway ; Citri Reticulatae Pericarpium ; flavonoids ; anticancer ; mechanism ; phenotype ; Angelica sinensis polysaccharide ; Astragalus membranaceus polysaccharide ; hexokinase 2 ; glycolysis ; JAK2/STAT3 pathway ; liver regeneration ; Holoptelea integrifolia ; MMP-9 ; wound healing ; friedelin ; oxalactam A ; macrolactam ; anti-Rhizoctonia solani ; Penicillium oxalicum ; molecular dynamics ; non-alcoholic fatty liver disease (NAFLD) ; natural products ; terpenoids ; mechanisms ; treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Sprache: Englisch
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Several epidemiological studies have demonstrated that oxidative stress is associated with a number of health disorders, including cardiovascular malfunction, certain types of cancer, diabetes mellitus, many other auto-immune diseases, and even ageing. The body possesses multiple mechanisms to counteract oxidative stress, which employ antioxidant compounds that are either naturally generated in situ (endogenous antioxidants) or externally supplied through food (exogenous antioxidants). These antioxidants are able to counteract oxidative stress, thanks to their ability to neutralize excess free radicals and protect the cellular lipids, proteins, and DNA from molecular damage. Exogenous antioxidants from the diet are of increasing interest because of their beneficial role in maintaining good health and in preventing chronic diseases. Indeed, a diet rich in dietary antioxidants, especially from fruits and vegetables, has been correlated with a successful prevention and lower incidence of several degenerative pathologies, including obesity, diabetes, cardiovascular diseases, and cancer. This Special Issue of Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature, examining the role of diets rich in antioxidant compounds in the prevention of chronic diseases and the characteristics of the antioxidants included in such diets.
    Schlagwort(e): QH301-705.5 ; antioxidants ; chronic diseases ; dietary supplementation ; human health ; prevention ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Diet and nutrition are key tools in promoting health and reducing the comorbidities of chronic diseases. There are thousands of biomolecules in fruits, vegetables, wild and medicinal plants, other land and marine organisms, which can exert functional and health-promoting effects through bioactivity beyond nutrition. From the enormous amount of knowledge generated from different natural bioactive ingredients present in foods, we are aiming to bring together experts working in different fields of food, nutrition, and health, in order to work on this Special Issue, with a comprehensive collection of papers to gain insight into the most promising bioactive compounds in different foods, to improve the preservation of bioactivity during the food processing chain, and to provide scientific evidence of the efficacy of key bioactives in foods in preventing disease and improving health and wellbeing.
    Schlagwort(e): QH301-705.5 ; TX341-641 ; Health ; Bioactives ; Nutrition and Metabolism ; Nutrients ; Bioavailability ; Food ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: The diversity of wood and non-wood forest products is enormous and reflected in their anatomical, physical and chemical properties as well as their potential applications. Special attention should be given to lesser-known species and even to invasive species, which may be profitable when properly managed, thereby decreasing the overexploitation of threatened species. Besides the market importance of stem wood, other tree components and non-wood forest products, often regarded simply as forest residual materials, are valuable forest resources with various potential applications that can strengthen the circular economy. Assessing the characteristics of these diverse materials, such as their structure and anatomy as well as their physical and chemical properties, is fundamental for evaluating their potential and increasing high-quality end-uses. This knowledge will also contribute to sustainable forest management with enhanced forest diversity and species conservation in addition to the reinforcement of certification and environmental policies.
    Schlagwort(e): Calamus zollingeri ; Calamus ornatus ; dynamic vapor sorption ; basic density ; volumetric swelling ; white rot ; mold ; Quercus suber L. ; seasonal variation ; cuticular waxes ; leaves ; new species ; morphology ; wood ; properties ; chemical composition ; spectroscopy ; chemometrics ; unconventional species ; Quercus suber ; cork borer ; cork ; phenolics ; tropical species ; wood anatomy ; wood density ; wood color ; multivariate analysis ; species diversity ; dark-brown zone ; lenticular filling tissue ; quantitative anatomical characteristics ; Quercus variabilis ; reproduction cork ; scanning electron microscopy ; sclereid ; virgin cork ; Cytisus scoparius ; liquefied ; optimization ; eco-valorization ; agro-industrial residues ; Asparagaceae ; lignocellulose ; crystalline cellulose ; syringyl/guaiacyl ; anatomy ; Tilia amurensis Rupr. ; Tilia mandshurica Rupr. & Maxim. ; branch ; wood properties ; papermaking material ; tropical timber ; color parameters ; mid-infrared spectroscopy ; FTIR ratios ; environmental factors ; West African Sahel ; Cupressus funebris Endl. wood ; wood knots ; physical properties ; wood color properties ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
    Sprache: Englisch
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: New scientific advances in different areas have allowed the design of more precise strategies for the prevention and treatment of metabolic disorders through nutrition. In this context emerges the term Precision Nutrition, a new approach that takes advantage of scientific knowledge about the interaction of internal and external environmental factors to develop dynamic and precise nutritional recommendations. Therefore, Precision Nutrition includes personalized advice based on genetics and well-documented gene–nutrient–phenotype interactions, as well as other factors such as individual metabolome, transcriptome, and microbiota profile; food behavior; and dietary, physical activity, and life-style habits; and the resulting interactomes. Precision Nutrition should be based at least on three sequential steps: conventional nutritional approaches (considering age, gender, and physiological states); the incorporation of nutritional and health status information (e.g., metabolites, physical and nutritional behavior); and the genetic baggage including multiomics functional integration.
    Schlagwort(e): dietary parameters ; carbohydrate intake ; obesity ; single nucleotide polymorphism ; CLOCK gene ; rs3749474 ; sodium intake ; hypertension ; single-nucleotide polymorphism ; personalized nutrition ; dietary vitamin A ; body fat ; UCP ; retinoic acid ; PBMC ; genetic variant ; weight loss ; nutrigenomics ; dietary intervention ; FTO gene ; dietary protein ; dietary carbohydrates ; dietary fat ; macronutrients ; gene-diet interaction ; glucose homeostasis ; glaucoma ; polygenetic-risk scores ; gene-gene interaction ; gene-nutrient interaction ; precision medicine ; childhood ; insulin resistance ; adipokine ; metabolomics ; biomarkers ; ELOVL ; metabolic alterations ; Mexican population ; Single Nucleotide Polymorphisms ; pediatrics ; cardiometabolic risk factors ; precision nutrition ; eating behavior ; nutrigenetics ; microbiota ; metabolic syndrome ; Mediterranean diet ; genetic risk score ; HELENA ; adolescents ; sex ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
    Sprache: Englisch
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Publikationsdatum: 2024-04-05
    Beschreibung: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: The intention of this Special Issue is to focus on new aspects of drug discovery, including the search for new molecular targets of various diseases, the creation of new modern methods for diagnosing diseases, the development of new test systems and kits for assessing the selectivity and effectiveness of new drugs, the study of the molecular mechanisms of biologically active compounds, the formulation of new drugs, pharmacokinetic and pharmacodynamic studies, and preclinical trials of important molecules.
    Schlagwort(e): Streptococci ; antimicrobials ; QSAR ; MD simulation ; Kunitz-type peptides ; neuroprotective activity ; sea anemones ; TRPV1 ; P2X7R ; Parkinson’s disease (PD) ; diffuse large B cell lymphoma (DLBCL) ; deep neural network ; drug discovery ; drug combination ; biomarker ; cancer severity ; cancer prognosis ; MAFB ; tumor-associated macrophages ; prostate cancer ; photodynamic therapy ; magnetic resonance imaging ; ex vivo ; anti-inflammatory substance ; N-acylhydrazone ; naphthyl-N-acylhydrazone ; LASSBio-1524 analogues ; phosphacoumarin ; azomethine ylide ; cycloaddition ; anti-cancer ; cytotoxicity ; quantum chemistry ; pravastatin ; metformin ; radiation-induced intestinal injury ; minipigs ; epithelial regeneration ; inflammation ; arylazo sulfones ; DNA binding ; DNA cleavage ; DNA photocleavage ; A375 melanoma cells ; molecular docking ; radicals ; N–S bond homolysis ; platinum(II) ; five-coordinate complexes ; glycoconjugation ; cytotoxic activity ; protein X-ray structure ; lipophilicity ; natural products ; acetylcholinesterase inhibitors ; butyrylcholinesterase inhibitors ; Alzheimer’s disease ; central nervous system ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; glutamic acid ; n/a ; direct mass spectrometry ; neurodegeneration ; 6-OHDA ; targeted mass spectrometry ; mitochondrial dysfunction ; myo-inositol ; metabolomics ; bile acids ; subacute mild traumatic brain injury ; age-related macular degeneration ; metabolic pathways ; energy metabolism ; midbrain ; Alzheimer’s disease ; biomarkers ; 1H NMR ; Parkinson’s disease dementia ; GC-MS ; pathogenesis ; tricarboxylic acid cycle ; micro-dialysis ; 13C-labeled succinate ; metabolism ; lipidomics ; dementia with Lewy bodies ; fatty acid ; prodromal Parkinson’s disease ; malonate ; cerebral ischemia ; mass spectrometry ; retinal pigment epithelium ; excitotoxicity ; endothelin-1 ; reperfusion ; C. elegans ; Streptomyces venezuelae ; ?-synuclein aggregates ; natural product ; fatty acid metabolism ; imaging mass spectrometry ; LC-MS ; drusen ; cerebral palsy ; plasma ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 13
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
    Schlagwort(e): QH301-705.5 ; SF1-1100 ; Q1-390 ; n/a ; muscle texture ; fractal analysis ; fish welfare ; Danio rerio ; motivation ; histopathology ; elevated phosphate concentrations ; sharks ; welfare ; African catfish (Clarias gariepinus) ; feed efficiency ; fighting ability ; aggressive interaction ; social rank ; boldness ; ethology ; fisheries management ; physiological response ; FishEthoBase ; welfare scores ; welfare criteria ; stress ; pain ; stereotypical behaviour ; Scyliorhinus canicula ; animal behavior ; welfare enhancement ; social communication ; nociception ; negative and positive affect ; aggression ; fertilisation success ; risk analysis ; aquaculture ; hematology ; Amyloodinium ocellatum ; framework ; structural complexity ; territorial ; growth ; positive welfare ; social stress ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The re-use of industrial food residues is essential in the general framework of rational waste handling and recycling, which aims at the minimizing environmental impact of food production and producing functional food ingredients. Agri-food processing waste has long been considered a valuable biomass with a significant polyphenol load and profile. Polyphenols, aside from being powerful antioxidants that confer inherent stability to a variety of foods, may possess versatile bioactivities including anti-inflammatory and chemopreventive properties. The valorization of agri-food waste as a prominent source of polyphenols stems from the enormous amount of food-related material discharged worldwide and the emerging eco-friendly technologies that allow high recovery, recycling, and sustainable use of these materials. This book addresses the concept of recovering natural polyphenolic antioxidants from waste biomass generated by agri-food and related industrial processes and presents state-of-the-art applications with prospect in the food, cosmetic, and pharmaceutical industries.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; valorization ; ultrasound assisted extraction ; microwave assisted extraction ; Box–Behnken design ; HPLC-DAD-q-TOF-MS ; Dioscorea batatas ; green oleo-extraction ; grape marc ; quantitative analysis ; natural antioxidants and flavors ; antioxidant ; infrared-assisted extraction ; anti-ageing ; anthocyanins ; liquid chromatography-mass spectrometry ; Chinese yam ; functional food ; extraction ; olive mill wastewater ; adsorbents ; relative solubility simulation ; HPLC-fluorometric detector (FLD)–MS ; saffron ; antioxidants ; food-grade solvents ; Mango ; zero-waste biorefinery ; response surface methodology ; ophthalmic hydrogel ; olive leaves ; sonotrode ultrasonic-assisted extraction ; vegetable oils and derivatives ; anti-inflammatory ; skin whitening ; phenolics ; Brewers’ spent grains ; proanthocyanidins ; brewer’s spent grain ; anti-inflammatory and antioxidant activity ; antimicrobial activity ; by-products ; antiplatelet activity ; phenanthrenes ; wine lees ; bioactive compounds ; deep eutectic solvents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Mycotoxins are secondary metabolites produced by molds. Although the primary role of these toxins is thought to be related to the colonisation of the environment by the fungi—mycotoxins are able to kill other micro-organisms (antimicrobial effect) and/or plant cells (mycotoxin-producing fungi being necrophagic)—the exposure of animals and humans to mycotoxins through the consumption of mycotoxin-contaminated food and feeds leads to diseases and death. Among the different mycotoxins described (more than 350 mycotoxins have been identified), deoxynivalenol (DON or vomitoxin) produced by Fusarium species has attracted the most attention due to its prevalence and toxicity. DON is part of a family of mycotoxins called trichothecenes that are small sesquiterpenoids with an epoxide group at positions 12–13 allowing their binding to ribosomes causing the so-called ribosome stress response, characterized by the activation of various protein kinases that lead to alterations in gene expression and cellular toxicity in animals, humans and plants. Here, we compiled very recent findings regarding DON and its derivatives: i) their prevalence in human food; ii) the estimation of the exposure of humans to them using biological markers; iii) their roles during plant–fungi interaction; iv) the alteration caused by them in animals and humans, particularly at low doses that are close to those observed in farm animals and human consumers; v) possible strategies to decrease their presence in food and feeds. Overall, this book will give the reader a clear and global view on this important mycotoxin produced by Fusarium species which is responsible for huge economic loss and health issues.
    Schlagwort(e): QH301-705.5 ; cell entry ; deoxynivalenol ; DON derivative ; cell effect ; trichothecene ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: This Urological Cancer 2020 collection contains a set of multidisciplinary contributions to the extraordinary heterogeneity of tumor mechanisms, diagnostic approaches, and therapies of the renal, urinary tract, and prostate cancers, with the intention of offering to interested readers a representative snapshot of the status of urological research.
    Schlagwort(e): renal cell carcinoma ; iron ; macrophages ; chelation therapy ; urothelial carcinoma ; transcriptome ; microtubule ; MAP1B ; prognosis ; KLF5 ; androgen receptor ; cell proliferation ; tumorigenesis ; prostate cancer ; precision medicine ; whole genome sequencing ; optical mapping ; therapy ; prostate carcinoma ; prostate mpMRI ; machine learning ; artificial intelligence ; deep learning ; neural network ; angiogenesis ; angiogenic growth factors ; antiangiogenic therapy ; renal tumors ; prevention ; α1-adrenoceptor antagonists ; anoikis ; vascularity ; research model ; oncogenes ; tumor suppressor genes ; MR-guided ; radiotherapy ; MRgRT ; stereotactic ablative radiotherapy ; stereotactic ablative radiation therapy (SABR) ; renal cell cancer ; RCC ; online adaptive ; [68Ga]Ga-PSMA PET/CT ; dual-time point imaging ; delayed imaging ; biphasic imaging ; lesion positivity rate ; CXCL9 ; PD1 ; PD-L1 ; stage T1 NMIBC ; prostatic neoplasms/mortality ; prostatic neoplasms/epidemiology ; SEER Program ; bladder cancer ; transurethral resection ; en-bloc resection ; CPT1A ; fatty acids ; serine ; androgen response ; ROS ; oxidative stress ; DONSON ; Downstream Neighbor of SON ; biomarker ; metastatic spread ; diagnosis ; differential diagnosis ; histopathology ; immunohistochemistry ; stroma signature ; patient-derived xenografts ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 17
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Concerns have been raised with respect to the state of high-altitude and high-latitude treelines, as they are anticipated to undergo considerable modifications due to global changes, and especially due to climate warming. As high-elevation treelines are temperature-limited vegetation boundaries, they are considered to be sensitive to climate warming. As a consequence, in this future, warmer environment, an upward migration of treelines is expected because low air and root-zone temperatures constrain their regeneration and growth. Despite the ubiquity of climate warming, treeline advancement is not a worldwide phenomenon: some treelines have been advancing rapidly, others have responded sluggishly or have remained stable. This variation in responses is attributed to the potential interaction of a continuum of site-related factors that may lead to the occurrence of locally conditioned temperature patterns. Competition amongst species and below-ground resources have been suggested as additional factors explaining the variability in the movement of treelines. This Special Issue (book) is dedicated to the discussion of treeline responses to changing environmental conditions in different areas around the globe.
    Schlagwort(e): QH301-705.5 ; QK1-989 ; Q1-390 ; n/a ; tree seedling recruitment ; shrubline ; light quality ; higher altitude ; precipitation ; experimental rain exclusion ; Pinus cembra ; Changbai Mountain ; treeline dynamics ; fungal ecology ; thermal continentality ; tree regeneration ; elevational transect ; monitoring ; conifer shrub ; plant water availability ; permafrost ; foehn winds ; treeline ; Holocene ; nitrogen cycling ; carotenoids ; timberline ; 15N natural abundance ; spectrometer ; basal area increment ; palynology ; xylem embolism ; diversity ; elevational treeline ; European Alps ; temperature ; tree line ; winter stress ; photosynthetic pigments ; Pinus sibirica ; westerly winds ; relative air humidity ; ecosystem manipulation ; Larix decidua ; microsite ; polar treeline ; Central Austrian Alps ; Switzerland ; multi-stemmed growth form ; conifers ; forest edge ; history of treeline research ; soil drought ; dendroclimatology ; knowledge engineering ; Rocky Mountains ; apical control ; cloud ; postglacial ; alpine timberline ; space-for-time substitution ; climate change ; expert elicitation ; shoot elongation ; pit aspiration ; climate warming ; climate zone ; alpine treeline ; refilling ; Abies sibirica ; growth trend ; western Montana ; light quantity ; Picea abies ; Mediterranean climate ; forest climatology ; altitude ; environmental stress ; sub-Antarctic ; Erman’s birch ; photoinhibition ; tocopherol ; elevational gradients ; NDVI ; long-term trends ; sap flow ; peat ; tree seedlings ; Southern Ocean ; chlorophyll ; non-structural carbohydrates (NSCs) ; drought ; upward advance ; remote sensing data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 18
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Forests cover 30% of the Earth’s land area, or nearly four billion hectares. Enhancing the benefits and ecosystem services of forests has been increasingly recognized as an essential part of nature-based solutions for solving many emerging global environmental problems today. A core science supporting forest management is understanding the interactions of forests, water, and people. These interactions have become increasingly complex under climate change and its associated impacts, such as the increases in the intensity and frequency of drought and floods, increasing population and deforestation, and a rise in global demands for multiple ecosystem services including clean water supply and carbon sequestration. Forest watershed managers have recognized that water management is an essential component of forest management. Global environmental change is posing more challenges for managing forests and water toward sustainable development. New science on forest and water is critically needed across the globe. The International Forests and Water Conference 2018, Valdivia, Chile (http://forestsandwater2018.cl/), a joint effort of the 5th IUFRO International Conference on Forests and Water in a Changing Environment and the Second Latin American Conference on Forests and Water provided a unique forum to examine forest and water issues in Latin America under a global context. This book represents a collection of some of the peer-reviewed papers presented at the conference that were published in a Special Issue of Forests.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; SD1-669.5 ; social capital ; Cambodia ; forest and water policy ; land use and land cover change ; shrubland ; “Forests to Faucets” ; precipitation gradient ; forest ecosystem management ; afforestation ; connectivity ; land use change ; forest operations ; Chile ; catchment management ; forest plantation ; climate change ; compound wildfire-water risk ; native forest ; hydrology ; wetland ; streamside native buffer ; sustainability ; participatory monitoring ; hydrological modeling ; timber harvesting ; water quality ; native forests ; source water protection ; global change ; forest hydrology ; community drinking-water ; SDGs ; drinking-water security ; Oregon ; forest ; aquatic-riparian ecosystems ; NDC ; heat: moisture index ; watershed management ; load ; Rhyacotriton ; ecohydrology ; nutrient concentrations ; multi-criteria analysis ; Loess Plateau ; dissolved organic matter ; US Pacific Northwest ; soil moisture ; agricultural lands ; water management ; water provision ; water supply ; forests ; post-fire hydrology ; grassland ; forest plantations ; restoration strategy ; riparian buffer zones ; Mekong ; riparian vegetation ; density management harvest ; SWAT model ; forest watersheds ; water governance ; Nenjiang River ; forestry ; ecosystem services ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; thermodynamic modeling ; molecular dynamics simulation ; poorly soluble drugs ; amorphous solid dispersions ; dissolution enhancement ; crystallization tendency ; continuous processing ; stability ; milling ; granulation ; thermal analysis ; amorphous ; ball milling ; pharmaceutical glass ; dissolution ; rebamipide ; poloxamer ; classification ; polyelectrolytes ; amorphisation ; self-assembly ; dissolution rate ; miscibility ; bioavailability ; solubility ; evaporation ; mesoporous ; polyelectrolyte excipient matrix ; polymer ; bicaludamide ; phase diagram ; Weibull dissolution model ; spectroscopic techniques ; anticancer drugs ; manufacturing methods ; nucleation ; molecular complex ; nanoaggregates ; enrofloxacin ; accelerated stability test ; solubility enhancement ; amorphous solid dispersion ; tadalafil ; process development ; amorphous polymeric salt ; Wood’s apparatus ; hot melt extrusion ; solid dispersions ; intrinsic dissolution rate ; solid dispersion ; interaction ; crystallization ; spray drying ; characterization ; ciprofloxacin ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 20
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Rivers have been intensively degraded due to increasing anthropogenic impacts from a growing population in a continuously developing world. Accordingly, most rivers suffer from pressures as a result of increasing dam and weir construction, habitat degradation, flow regulation, water pollution/abstraction, and the spread of invasive species. Science-based knowledge regarding solutions to counteract the effects of river degradation, and melding principles of aquatic ecology and engineering hydraulics, is thus urgently needed to guide present and future river restoration actions. This Special Issue gathers a coherent set of studies from different geographic contexts, on fundamental and applied research regarding the integration of ecohydraulics in river restoration, ranging from field studies to laboratory experiments that can be applied to real-world challenges. It contains 13 original papers covering ecohydraulic issues such as river restoration technologies, sustainable hydropower, fish passage designs and operational criteria, and habitat modeling. All papers were reviewed by international experts in ecology, hydraulics, aquatic biology, engineering, geomorphology, and hydrology. The papers herein well represent the wide applicability of ecohydraulics in river restoration and serve as a basis to improve current knowledge and management and to reduce arguments between different interests and opinions.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; Fish passage and migration ; Prioritization of river connectivity for sustainable fisheries ; Sustainable hydropower ; Spawning grounds ; Invasive species management ; Environmental flows ; Habitat modeling ; Dam/weir retrofitting and removal ; Riparian and aquatic vegetation dynamics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 21
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level.
    Schlagwort(e): QH301-705.5 ; genome stability ; Trisomies ; microtubule dynamics ; Checkpoints ; Inheritance ; Cell division ; centrosome ; Down Syndrome ; Cell motility ; Cell regulation ; chromosome segregation ; Microtubules ; Cell cycle ; kinetochore ; Cytoskeleton ; Cell reproduction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 22
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Dear Colleagues, When Hayflick and Moorhead coined the term “cellular senescence” (CS) almost 60 years ago, this phenomenon was understood as a mechanism, usually induced by activation of the DNA-repair machinery, to prevent uncontrolled proliferation. Meanwhile, additional beneficial roles for CS have been identified, such as embryonic development and wound healing. The senescence associated secretory phenotype (SASP) activated in most senescent cells (SC) signals to the immune system “come here and remove me”. In organisms with young and functional immune systems, occurring SC are usually detected and removed. If SC remain in the tissue expressing the SASP, this will cause not just a damaging local inflammation but can also induce remodeling and regeneration of the surrounding tissue as well as spreading of senescence. Old organisms show reduced regenerative potential and immune function which leads to accumulation of SC. Accordingly, accumulation of SC was observed in tissues of aged individuals, but importantly also in the context of age-related disorders, neurodegenerative, or cardiovascular diseases and others. Because of its detrimental effect of the surrounding tissue, accumulation of SC is not just a consequence, but can rather been understood as a major driver of aging. In line with this, recent studies described that removal of SC showed beneficial effects on healthspan and lifespan. This exciting research led to the discovery of “senolytics”, drugs which can kill SC. Given the heterogeneity of cell types that show senescence-like phenotypes, including heart muscle and post-mitotic neuronal cells, further research is required to unravel the molecular background that renders a cell type vulnerable to senesce. Additionally, it will be important to understand how senescence is cell type-specifically induced and which molecules serve as drug targets to prevent senescence and its spreading, or actively kill SC. This special issue will shed light on the molecular pathways of CS and inflammaging and on possible strategies to interfere with these processes. Dr. Markus Riessland Guest Editor
    Schlagwort(e): γH2AX ; Alzheimer’s disease ; DNA damage ; mild cognitive impairment ; senescence ; secreted protein acidic and rich in cysteine ; regeneration ; homeostasis ; cellular senescence ; biology of aging ; neurodegeneration ; brain ; geroscience ; senolytics ; tauopathy ; cancer ; stress response ; post-mitotic ; neuronal senescence ; amyotrophic lateral sclerosis ; senescence-associated secretory phenotype (SASP) ; cell-cycle ; melanoma ; pancreatic adenocarcinoma ; tumor infiltration ; chemotherapy resistance ; prostate ; inflammation ; AIM2 inflammasome ; POP3 ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 23
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Ranaviruses and other viruses within the family Iridoviridae, infect a wide range of ecologically and commercially important ectothermic vertebrates, i.e., bony fish, amphibians, and reptiles, and invertebrates, including agricultural and medical pests and cultured shrimp and crayfish, and are responsible for considerable morbidity and mortality. Understanding the impact of these various agents on diverse host species requires the combined efforts of ecologists, veterinarians, pathologists, comparative immunologists and molecular virologists. Unfortunately, investigators involved in these studies often work in discipline-specific silos that preclude interaction with others whose insights and approaches are required to comprehensively address problems related to ranavirus/iridovirus disease. Our intent here is to breakdown these silos and provide a forum where diverse researchers with a common interest in ranavirus/iridovirus biology can profitably interact. As a colleague once quipped, “Three people make a genius.” We are hoping to do something along those lines by presenting a collection of research articles dealing with issues of anti-viral immunity, identification of a potentially novel viral genus exemplified by erythrocytic necrosis virus, viral inhibition of innate immunity, identification of novel hosts for lymphocystivirus and invertebrate iridoviruses, and modelling studies of ranavirus transmission. Collectively these and others will exemplify the breadth of ongoing studies focused on this virus family.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; risk assessment ; n/a ; CQIV ; mathematical models ; amphibian ; iridovirus ; ISDL ; Exopalaemon carinicauda ; viral load ; virus isolation ; European chub ; outbreak ; Unconventional T cell ; early detection ; susceptible species ; viral immune evasion ; DNA virus ; Rana grylio virus ; antibody ; intracellular localization ; Rana grylio virus (RGV) ; British Columbia ; Iridoviridae ; Andrias davidianus ranavirus ; viral infection ; susceptible-infected (SI) models ; yeast two-hybrid (Y2H) ; prevalence ; host-pathogen interactions ; Pacific herring ; Procambarus clarkii ; Bayesian inference ; eDNA ; amphibians ; Artemia spp. ; ranavirosis ; cross-species transmission ; FV3 ; SHIV ; Gryllus bimaculatus ; Pacific salmon ; NF-?B ; cricket ; IIV-6 ; virus binding ; erythrocytic necrosis virus (ENV) ; envelope protein ; iridovirus core proteins ; emerging infection ; host ; Ranavirus ; white head ; Rana temporaria ; Imd ; biosecurity ; antiviral immunity ; Decapodiridovirus ; endemic disease ; Macrobrachium rosenbergii ; co-immunoprecipitation (Co-IP) ; Common frog ; aquatic animals ; virus surveillance ; immunomodulators ; frog virus 3 ; ELISA ; DIV1 ; megalocytivirus ; Lymphocystis disease virus ; bearded dragon ; susceptibility ; protein interaction ; Pogona vitticeps ; viral erythrocytic necrosis (VEN) ; histopathology ; epidemiology ; native-fish conservation ; viral transmission ; Sparus aurata ; immunohistochemistry ; lizard ; disease dynamics ; immunofluorescence ; transmission modelling ; Macrobrachium nipponense ; interferon ; nonclassical MHC ; heparan sulfate ; ranavirus ; Mexico ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 24
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: In the past 20 years, karst desertification control has produced remarkable results, and the South China karst has been a global hotspot for greening. However, in the new stage of karst desertification control, the functional lag of forest ecosystems and the insufficient supply capacity of ecosystem services are gradually becoming prominent. We not only lack systematic research on vulnerability and resilience, structure and stability, ecological assets and services, carrying capacity and ecological security, and service trade-offs/synergies and optimization in controlled ecosystems. There is still a lack of research on the ecological processes of newly constructed forests in improving ecosystem functions and services. Therefore, this reprint mainly focuses on the research improvement of forest ecosystem functions in karst desertification control. This includes the improvement mechanism of ecosystem structure, function, and services, the mechanism of ecosystem service tradeoff/synergy, and function optimization. An optimization model of ecosystem function and an improvement path for eco-product supply are introduced. The role of functional traits in the maintenance of ecological function and services is also established, and social–ecological responses to afforestation in karst desertification control are discussed.
    Schlagwort(e): structural trait ; element trait ; physiological trait ; leaf ; root ; karst ; ecosystem service supply ; value accounting ; eco-industry ; karst desertification environment ; farmland hydrological cycle ; agroforestry ; agronomic measures to water saving ; planting combinations ; investment strategy ; plant adaptability ; soil ; response ; biodiversity ; ecosystem services ; forests ; karst desertification ; plant functional traits ; structure ; landscape security pattern ; sensitivity ; landscape connectivity ; Guanling County ; Guizhou ; ecological products ; value realization ; ecological industry ; resilient landscape ; rural planning ; resilience assessment ; karst rocky desertification control areas ; karst forest ; vegetation water use strategy ; hydrogen and oxygen stable isotopes ; hydrologic niche separation ; principal component analysis ; redundancy analysis ; karst rocky desertification area ; species diversity ; evaluation indicator systems ; fuzzy integrated evaluation ; karst spring ; dissolved organic carbon/nitrogen ; rocky desertification ; terrestrial ecosystem ; soil aggregate stability ; soil nutrients ; vegetation restoration ; karst rocky desertification ; forest ; karst desertification control ; loquat ; intercropping peanut ; N2O emission ; Abies fanjingshanensis ; microbial carbon use efficiency ; physicochemical indices ; bacteria ; fungus ; structural optimization ; water and fertilizer regulation ; functional improvement ; forests ecosystem ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Sprache: Englisch
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  • 25
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: It is currently apparent that extracellular ATP's physiological effect is mediated by its interaction with specific purinergic receptors. All purinergic receptors are divided into P1-purinoreceptors and P2-purinoreceptors. Each of the subtypes is divided into a number of families. For instance, P2 receptors are divided into P2X and P2Y receptors according to the mechanism by which their effect is realized: P2Y are G-protein-coupled receptors, while P2X receptors are ligand-operated ion channels. P2X receptors are important molecular therapeutic targets, the malfunctioning of which leads to severe complications in the physiology of humans and animals and causes dangerous diseases. The search for compounds that can modulate the function of purinergic receptors can lead to the creation of new drugs that are effective in central and peripheral nervous system and immune system disease treatment, including neuroinflammation, hypoxia/ischemia, epilepsy and neuropathic pain. In this Special Issue, we wish to offer a platform for high-quality publications on the latest advances in the identification of P2X/Y- and P1-receptor blockers, functions and regulation by them; the characterization of these receptor signaling networks and crosstalk; mechanisms underlying the role of purinoceptors in neurodegenerative illnesses as well as chronic neuronal changes following acute noxious damage and therapeutic opportunities associated with regulation of purinergic receptor activity.
    Schlagwort(e): adenosine receptors ; adipogenesis ; osteogenesis ; adipose tissue ; bone marrow ; obesity ; neonatal seizures ; development ; ATP ; purinergic signalling ; P2X7 receptor ; endometriosis ; adenosine ; P2Y ; P2X ; ectonucleotidases ; pain ; inflammation ; endometrium ; CD73 ; CD39 ; P2Y2 receptor ; P2X4 receptor ; canine ; dog ; DH82 ; macrophage ; neuroinflammation ; antinociception ; cerebral ischemia ; oxygen-glucose deprivation ; A2B receptors ; oligodendrocyte differentiation ; demyelination ; retina ; purinergic modulation ; glycinergic neurotransmission ; microglia ; neurodegeneration ; glycine transporters ; guanosine ; stroke ; neuroprotection ; purinergic signaling ; purinergic receptors ; autoimmune disease ; astroglia ; G protein-coupled receptor 17 (GPR17) ; neurite outgrowth ; montelukast ; NG2 ; ex vivo organotypic brain slice co-culture ; neurodegeneration and neuroregeneration ; n/a ; macrophages ; P2X7R ; pore formation ; inflammasome activation ; inflammatory diseases ; gallic acid ; visceral pain ; depression ; hippocampus ; spinal cord ; dorsal root ganglion ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 26
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Afforestation/reforestation (or forestation) has been implemented worldwide as an effective measure towards sustainable ecosystem services and addresses global environmental problems such as climate change. The conversion of grasslands, croplands, shrublands, or bare lands to forests can dramatically alter forest water, energy, and carbon cycles and, thus, ecosystem services (e.g., carbon sequestration, soil erosion control, and water quality improvement). Large-scale afforestation/reforestation is typically driven by policies and, in turn, can also have substantial socioeconomic impacts. To enable success, forestation endeavors require novel approaches that involve a series of complex processes and interdisciplinary sciences. For example, exotic or fast-growing tree species are often used to improve soil conditions of degraded lands or maximize productivity, and it often takes a long time to understand and quantify the consequences of such practices at watershed or regional scales. Maintaining the sustainability of man-made forests is becoming increasingly challenging under a changing environment and disturbance regime changes such as wildland fires, urbanization, drought, air pollution, climate change, and socioeconomic change. Therefore, this Special Issue focuses on case studies of the drivers, dynamics, and impacts of afforestation/reforestation at regional, national, or global scales. These new studies provide an update on the scientific advances related to forestation. This information is urgently needed by land managers and policy makers to better manage forest resources in today’s rapidly changing environments.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; SD1-669.5 ; simulation modeling ; shear strength ; stand structure ; vegetation restoration ; surface runoff ; soil and water conservation function ; soil enzymes ; riverbank ; evapotranspiration ; human activity ; afforestation ; Artemisia ordosica ; forest cover ; precipitation variation ; soil bioengineering ; base flow ; Poyang Lake Basin ; in situ calibration ; quantification ; chlorophyll fluorescence ; photoprotection ; remote sensing ; root distribution ; ecosystem model ; CASA ; afforestation ecosystem ; phenophase ; vegetation cover change ; soil characteristics ; Robinia pseudoacacia L. and Pinus tabulaeformis Carr. mixed plantations ; composted pine bark ; water-energy balance ; sediment load ; soil respiration ; energy partitioning ; soil microbial biomass ; transpiration ; net primary productivity ; spatio-temporal scales ; seedling quality ; peat moss ; fresh pine sawdust ; understory plants ; ring-porous trees ; different climatic conditions ; dye tests ; structural equation model ; Loess Plateau ; evapotranspiration (ET) ; Pinus engelmannii Carr. ; empirical statistics ; heat dissipation probes ; MODIS ; slope change ratio of cumulative quantities (SCRCQ) ; soil water balance ; LAI ; climate fluctuation ; BTOPMC model ; living brush mattress ; vegetation greening ; streamflow ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 27
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: This Special Issue, entitled “Nutraceuticals and Functional Foods: Bridging Health and Food Under a New Perspective”, aims to approach the current state-of-the-art research on nutraceuticals and functional foods. The main issue in this field of research is the sustainability and recovery of bioactive substances from vegetal- or animal-origin byproducts to project and realize novel food supplements and nutraceuticals. Low environmental impact, safety, new food sources and analytical methodologies are of growing interest in the research area of food. The perspective approach addresses the mechanism of action of nutraceuticals, safety and functional foods and nutraceuticals’ mechanisms of action, revealing new possibilities for their use as tools in a complementary proactive approach to certain health issues to prevent the onset of health conditions or to be used in subjects who do not qualify for a conventional therapeutical approach. The areas involved in this perspective range from food chemistry and analysis to nutrition and from safety to sustainability; new therapeutical approaches and novel techniques of analysis and formulation are also involved, which require a wide inter- and multi-disciplinary approach. The overall assessment of these aspects creates new challenges for research and also impacts sustainability, health and safety. This Special Issue may also consider the bridging of health and food in their different declinations from a new perspective.
    Schlagwort(e): Food and by-products ; Functional foods and novel sources ; Health and beneficial properties ; Nutraceuticals and novel sources ; Prevention ; Clinical data ; In vitro and in vivo data ; Nanonutraceuticals and nanodelivery ; Clinical experience ; Formulation and novel sources ; Mechanism of action ; Analytical aspects ; Safety ; Interactions with active molecules. ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
    Sprache: Englisch
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  • 28
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually partitioned into three distinct regions, known as classes I, II, and III, which, to varying extents, can be found conserved in nonmammalian jawed vertebrates, such as bony fish, amphibians, and bird lineages. The MHC gene region is characterized particularly by the expression of class I and class II glycoproteins that bind peptides derived from intracellular or extracellular antigens to circulating T-cells. While this expressed antigenic specificity remains the predominant interest with respect to MHC function and polymorphism in a population, a broader concept has emerged that examines the MHC as a multifunctional polymorphic controller that facilitates and regulates genome diversity with a much greater array of functions and effects than just MHC-restricted antigen recognition. This volume of 19 reprints presented by various experts and collected from the Special Issue of Cells on “MHC in Health and Disease” covers a broad range of topics on the genomic diversity of the MHC regulatory system in various vertebrate species, including MHC class I, II, and III genes; innate and adaptive immunity; neurology; transplantation; haplotypes; infectious and autoimmune diseases; fecundity; conservation; allelic lineages; and evolution. Taken together, these articles demonstrate the immense complexity and diversity of the MHC structure and function within and between different vertebrate species.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; HCP5 ; n/a ; camels ; MHC ; STK19 ; major histocompatibility complex ; human papillomavirus (HPV) ; T-cell receptor ; T1DGC ; bottleneck ; micro-mini-pigs ; life history ; computational analysis ; hepatocellular carcinoma ; phase ; Bactrian camel ; NSDK ; melanoma ; antigen ; autoimmune disease ; RD ; selection ; disease resistance ; autoimmunity ; ancestral haplotype ; Ski complex ; DXO ; high-throughput sequencing ; conservation genetics ; SVA ; lncRNA ; ankylosing spondylitis ; MHC genes ; viral peptides ; competing endogenous RNA (ceRNA) ; astrogliosis ; birds ; long-fragment super haplotype ; SNP ; RLR ; HLA polymorphism ; 5??3? RNA decay ; expression ; 3??5? mRNA turnover ; orthology ; long-read sequencing ; disease association ; dromedary ; polyomavirus ; MHC-II-associated sperm-egg recognition ; experimental medicine ; single nucleotide polymorphism (SNP) ; fish ; SKIV2L ; production trait ; molecular dynamics simulation ; Macaca fascicularis ; human endogenous retrovirus (HERV) ; concerted evolution ; polymorphism ; Old World camels ; MHC polymorphism ; protocol ; nonclassical ; gene duplication ; microglial reaction ; human leukocyte antigen-E ; SKI2W ; quantitative trait loci (QTL) studies ; antiviral immunity ; human immunodeficiency virus (HIV) ; founder effect ; giant panda ; domain movements ; BK virus ; promoter-proximal transcriptional pause ; type 1 diabetes (T1D) ; RP1 ; miR1236 ; KIR ; synaptic covering ; swine leukocyte antigen ; cynomolgus macaque ; HLA ; kidney transplantation ; ?2m knockout mice ; DOM3Z ; interferon ? ; ethnic populations in China ; ecology ; KIR–HLA pairs ; exosomes ; major histocompatibility complex (MHC) ; MHC-I-based mother-fetus recognition ; RNA quality control ; autoimmune diseases ; NELF-E ; haplotype ; genetic drift ; evolution ; nonhuman primate models ; HLA-B27 ; PNS/CNS interface ; risk genes ; pedigree ; MHC-I- and MHC-II-dependent inter-individual recognition ; regulation ; crested ibis ; reproductive performance ; nephropathy ; cancer ; nuclear kinase ; trichohepatoenteric syndrome ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 29
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; biorefinery ; polyphenols ; dynamic simulation ; Fucus distichus subsp. evanescens ; seaweeds ; phytochemicals ; Bifurcaria bifurcata ; Fucus vesiculosus ; kidney ; complex polysaccharides ; identification ; secondary metabolites ; phlorotannin ; cholinesterases ; eckol ; skin aging ; clinical trials ; dieckol ; fucoxanthin ; age-related macular degeneration ; photo-protection ; phytol ; Alzheimer’s disease ; fucosterol ; bone health ; nutraceutical ; papillomavirus ; red seaweed ; extraction ; osteoporosis ; fucoidan ; marine algae ; chemo-preventive agent ; ischemia-reperfusion injury ; hyperpigmentation ; bone metabolism ; bioactives ; macroalgae ; beta-secretase ; laurinterol ; prebiotics ; dietary fibre ; NMR spectroscopy ; health effects ; bromophenols ; beta-amyloid aggregation ; kahalalide F ; Padina pavonica ; carotenoids ; insulin glycation ; skincare ; mushroom tyrosinase ; polyunsaturated fatty acids ; fatty acid ; in vivo studies ; apoptosis ; algae ; biological activities ; Symphyocladia latiuscula ; Fucus serratus ; mass spectrometry ; Laminaria digitata ; high-speed counter-current chromatography ; isolation and purification ; K14HPV16 ; amyloid-? aggregation ; VEGF ; melanin ; Laurencia ; seaweed ; organotypic culture ; Saccharina latissima ; ex vivo ; genotoxicity assay ; gut microbiota ; phlorotannins ; eckmaxol ; high value applications ; Ecklonia maxima ; B16F10 ; neuroprotection ; linear diterpenes ; antitumoral ; Ecklonia cava ; cancer ; breast cancer explants ; osteosarcoma ; oxidative stress ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 30
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Nowadays, diet-related non-communicable diseases and their complications are one of the most important public health problems worldwide. Food supplements and functional foods are considered food products which contribute to the achievement of optimal nutritional well-being, health status, and quality of life through reducing the risk of diseases and promoting the appropriate function of human organs and systems. Nowadays, the assessment of these functional foods and the study of their implications in nutrition and health are important challenges in societies of developed countries where consumers increasingly demand foods with added value beyond the provision of nutrients and the satisfaction of appetite. In this reprint, the characterization of the nutritional composition and phytochemicals of functional foods and food supplements as well as the evaluation of their potential health benefits in different disorders and diseases through clinical trials or preliminary studies are addressed.
    Schlagwort(e): food supplement ; folic acid ; pregnancy ; food safety ; health claims ; nutrition ; Amazonian fruits ; composition ; metabolic effects ; royal jelly ; acetylcholine ; fatty acid ; ophthalmology ; dry eye ; magnesium ; pharmacy ; food supplements ; drugstore ; functional foods ; healthy eating ; credibility ; extrinsic attributes ; conjoint analysis ; Mediterranean diet ; phytonutrients ; dietary recommendations ; healthy diet ; polyphenols ; flavonoids ; carotenoids ; organosulfur ; caffeine ; antidiabetic activity ; antioxidant activity ; inhibition of α-glucosidase ; inhibition of α-amylase ; inhibition of collagenase ; kombucha ; bacteria ; yeast ; metagenome ; metabolome ; tea polyphenols ; antioxidants ; Glossogyne tenuifolia ; exercise ; forelimb grip strength ; lactate ; ammonia ; creatine kinase ; medium-chain triglycerides (MCTs) ; obesity ; energy expenditure ; diet-derived fat ; postprandial resting metabolism ; sedentary ; octanoic acid ; decanoic acid ; creatine ; magnetic resonance spectroscopy ; cost-effectiveness ; brain ; muscle ; healthcare ; anthocyanins ; organosulfur compounds ; tannins ; phenolic acids ; Persea americana ; non-alcoholic liver disease ; liver enzymes ; inflammation ; oxidative stress ; novel foods ; novel ingredients ; extracts ; risk assessment ; dietary supplements ; HPLC ; food authenticity ; neural tube defects ; food ; food analysis ; food ingredients ; infant formula ; kynurenic acid ; (poly)phenol-based supplement ; pharmacokinetics ; urinary excretion ; bioavailability ; inter-individual variability ; non-invasive brain stimulation ; TMS ; a-tDCS ; indicaxanthin ; brain food ; cortical excitability ; homeostatic plasticity ; trans-resveratrol ; regulation ; labels ; nutrition claims ; high-performance thin-layer chromatography ; HPTLC ; glutamine ; intestinal stem cells ; crypt ; proliferation ; burns ; micronutrient ; health claim ; labeling ; European legislation ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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  • 31
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: This book focuses on advanced research topics on human lactation, such as breastfeeding experiences, milk composition and production, COVID-19 and human milk, food allergens in human milk, the human milk microbiome, and the impacts of human milk on infant growth and development. The symposium proceedings aim to add diversity, passion, and innovation to lactation research and have a positive impact on mothers, infants, and communities worldwide, showcasing integrative mother/infant-centered research.
    Schlagwort(e): thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 32
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Carboxylic acids are truly central compounds in cellular metabolism. Carbon dioxide is captured from the atmosphere through formation of carboxylic groups and is also released, in part, by decarboxylation reactions. The reactivity of the carboxylic group with amino- or hydroxyl-groups enables the formation of peptide and ester bonds. The functionality of the carboxylic group is also of huge importance in our industrial world for a wide range of applications. The loosely bound hydrogen provides weak acid functionality, much desired for food industry applications in preservatives and flavour compounds. Citric acid is one of our oldest industrial fermentation products. The presence of two carboxylic groups, or a combination of one carboxylic group and another functional group, make the compounds interesting building blocks for polymer production. A number of carboxylic acids, including, e.g., lactic, succinic, 3-hydroxypropionic and itaconic acids, have been identified and recognized as suitable platform chemicals for a foreseen growing carbohydrate based economy. Economic margins are, however, tight when competing with petroleum based production, and production strains, fermentation technology and—not least—downstream processing, all need to be improved to enable viable commercial production. This Special issue will cover current developments within this exciting field. Topics will include: Fermentation physiology of natural carboxylic acid producers; screening and isolation of novel producers; metabolic engineering for improving intrinsic carboxylic acid production; metabolic engineering for expanding product range to non-endogenous carboxylic acids; production from lignocellulosic derived sugars or by-product streams; downstream processing for recovery of carboxylic acids; bioprocess design—including continuous processes and integration. All production organisms—fungi, yeasts, bacteria—are welcome.
    Schlagwort(e): QH301-705.5 ; bioprocess design ; downstream processing ; metabolic engineering ; strain evolution ; fermentation physiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 33
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Beer is a beverage with more than 8000 years of history, and the process of brewing has not changed much over the centuries. However, important technical advances have allowed us to produce beer in a more sophisticated and efficient way. The proliferation of specialty hop varieties has been behind the popularity of craft beers seen in the past few years around the world. Craft brewers interpret historic beer with unique styles. Craft beers are undergoing an unprecedented period of growth, and more than 150 beer styles are currently recognized. This Special Issue, Brewing and Craft Beer, comprises nine different works by researchers from five continents (North America, South America, Europe, Africa, and Oceania). This Special Issue reflects thus a broad perspective on the most important questions that concern the researchers in different parts of the world.
    Schlagwort(e): QH301-705.5 ; QD415-436 ; Q1-390 ; polyphenols ; n/a ; nutrient ; audible sound ; wet milling ; brewing technology ; robotics ; fast-screening ; lactose ; image analysis ; bottle refermentation ; beer aging ; sensory attributes ; brewing ; automation ; bitterness ; stout beer ; beer ; craft beer ; foamability ; Safrari ; adjuncts ; fermentation rate ; barley milling ; preference ; germ ; beer wort ; machine learning ; carbonation ; quality ; FAN ; granulometry ; sensory evaluation ; coffee ; beer acceptability ; computer vision ; fermentation ; economic contribution analysis ; short-chain fatty acids ; local value chain ; AEDA ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 34
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: We are facing a complicated public health issue in the form of global drug shortages, including antibiotics. Synthetic biology empowers the next generation of antibiotics development, bringing us into a new era.
    Schlagwort(e): global regulator ; milbemycins ; Streptomyces bingchenggensis ; SspH ; actinorhodin ; avermectin ; ceftriaxone ; hepatotoxicity ; metal complexes ; oxidative stress ; Streptomyces ; comparative transcriptome ; polyether antibiotics ; salinomycin ; exporter genes ; spectroscopic studies ; antioxidant capacities ; hepatic functions ; cancer cells ; cefotaxime ; Inonotus hispidus ; natural product ; biological activity ; medicinal fungi ; phytochemicals ; antimicrobial agents ; biosynthetic pathway ; secondary metabolites ; 1-benzazepine ; l-kynurenine ; genome mining ; biosynthesis ; iterative methyltransferase ; genetic dereplication ; cyclodipeptide ; OSMAC ; cytotoxicity ; Zymomonas mobilis ; antibiotic resistance ; ampicillin ; genome editing ; CRISPR−Cas12a ; resistance selection markers ; traditional Chinese medicine ; antifungal drug ; immune regulation ; combination of drugs ; fungal infection ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 35
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron–sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; n/a ; regeneration ; posttranslational modification ; H2O2 ; chilling stress ; thioredoxin reductase ; X-ray crystallography ; photosynthesis ; Chlamydomonas reinhardtii ; protein ; monodehydroascorbate reductase ; methionine sulfoxide ; cysteine reactivity ; symbiosis ; plant ; MALDI-TOF mass spectrometry ; thioredoxins ; redox homeostasis ; methionine sulfoxide reductases ; redox ; redox signalling ; chloroplast ; protein-protein recognition ; cyanobacteria ; specificity ; wheat ; methanoarchaea ; stress ; redox regulation ; dough rheology ; methionine sulfoxide reductase ; electrostatic surface ; Calvin cycle ; ALAD ; metazoan ; Arabidopsis thaliana ; baking ; cold temperature ; macromolecular crystallography ; protein oxidation ; function ; methionine oxidation ; development ; iron–sulfur cluster ; tetrapyrrole biosynthesis ; legume plant ; glutathionylation ; Calvin-Benson cycle ; adult stem cells ; carbon fixation ; plastidial ; methionine ; redox active site ; ROS ; water stress ; NADPH ; repair ; physiological function ; signaling ; thioredoxin ; antioxidants ; glutathione ; glutaredoxin ; flavin ; Isocitrate dehydrogenase ; thiol redox network ; ageing ; disulfide ; mitochondria ; chlorophyll ; proteomic ; cysteine alkylation ; ferredoxin-thioredoxin reductase ; SAXS ; regulation ; oxidized protein repair ; ascorbate ; redox control ; nitrosylation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 36
    Publikationsdatum: 2024-04-05
    Beschreibung: Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.
    Schlagwort(e): QH301-705.5 ; QD415-436 ; Q1-390 ; high-fat high-carbohydrate diet ; toxicity ; oxysterol ; n/a ; squalene cyclase ; sterol content ; sterolomics ; Polystichum ; Smith-Lemli-Opitz syndrome ; antifungals ; alkaloid ; cycloartenol synthase ; degeneration ; phytosterol ; Rhizopus arrhizus ; fibroblasts ; pod-blast ; fern ; cholesterol ; cytotoxic activity ; N-methylpiperidine. reductive deamination ; genetic disease ; isoprenoid ; steroid ; atherosclerosis ; granatane ; antioxidant ; wound healing ; development ; enzyme-assisted derivatization ; maturity ; terpene ; keratinocytes ; C4-demethylation complex (C4DMC) ; ?-sitosterol ; mesocarp ; sterol biosynthesis ; mechanism-based inactivators ; Mucorales ; gas chromatography-mass spectrometry (GC-MS) ; Girard reagent ; ROS ; sterol pattern ; N-methylcadaverine ; ?-tocopherol ; electrospray ionization-mass spectrometry ; human African trypanosomiasis ; HUVECs ; lipidomics ; campesterol ; triterpene ; oxyphytosterol ; leishmania ; Chagas disease ; LOX-1 ; sterol C24-methyltransferase ; antifungal effectivity ; ergosterol biosynthesis ; hormone ; glucose homeostasis ; retina ; solanaceae ; cholestanoic acid ; algal sterols ; cell migration ; withanolides ; insulin resistance ; Zingiber officinale ; posaconazole ; synthesis ; pre-diabetes ; pharmacognosy ; sterol ; 4-methylsterol ; oleanolic acid ; antiparasitic drugs ; lupeol ; oilseed ; aurelianolides ; divalent metal co-factor ligation ; bile alcohol ; phytosterols ; azoles ; infectious disease ; gingerols ; UV-radiation ; oil bodies ; ZnO ; sterol 14?-demethylase ; stigmasterol ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 37
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Predation and scavenging are pervasive ecological interactions in both terrestrial and aquatic environments. The ecology, evolution and conservation of predators and scavengers have received wide scientific attention and public awareness. However, the close connection that exists between predation and scavenging has not been emphasized until very recently. The recognition that carnivorous animals may obtain meat by either hunting prey or scavenging their carcasses has profound implications from individual behavior to population, community and ecosystem levels. However, many relevant questions still remain unexplored. This book deals with some of these questions, with the final aim to definitively dismiss the traditional view that predation and scavenging are disconnected ecological processes. This compendium of science may help to inspire ecologists, evolutionary biologists, paleontologists, anthropologists, epidemiologists, forensic scientists, anatomists, and, of course, conservation biologists in their stimulating and promising endeavor of achieving a more comprehensive understanding of carnivory in a rapidly changing world.
    Schlagwort(e): caching ; Capreolus capreolus ; carrion ; Eurasian lynx ; Lynx lynx ; Norway ; predation ; roe deer ; scavenging ; decomposition ; nitrogen ; nutrient recycling ; trophic cascade ; apex predators ; bear ; interspecific interactions ; moose ; wolf ; birds of prey ; foraging ; predators ; scavengers ; vision ; carcass ; confrontational scavenging ; disease risk ; facultative scavenger ; landscape of peril ; marine ecosystems ; parasite risk ; predator risk ; terrestrial ecosystems ; anthropogenic food ; diet ; urban habitats ; ecological functions ; carnivorous ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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  • 38
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: The future food systems will have to provide food and nutrition security while facing unprecedented sustainability challenges: this underlines the need for a transition to more sustainable food systems. Taking into account these premises and considering the complexity of food systems, this book aims to present original research articles, reviews, and commentaries concerning the following:Advancements in food and beverage;Dietary supplements, nutraceuticals, and functional food;Food allergy and public health;Food and nutritional toxicology;Food biotechnology and food processing;Food microbiology and food safety;Food packaging;Food safety and food inspection;Food security and environmental impacts;Food waste management;Nutrition and metabolism;Sustainable food systems and agro-ecological food production.
    Schlagwort(e): perceived consumer effectiveness ; green food consumption ; social trust theory ; social ideal theory ; psychological wellbeing ; China ; food additives ; food industry ; food safety ; health impacts ; maltitol ; metabolism ; sweeteners ; consumer’s perceptions and attitudes ; food security ; natural food products ; natural sweeteners ; sustainability ; food sovereignty ; reindeer herding ; food value chain ; Indigenous peoples ; COVID-19 pandemic ; the Arctic ; Western Siberia ; Yamal-Nenets Autonomous Okrug ; epistemic trust ; risk perception ; genetically modified food ; public acceptance ; partial least squares structural equation modeling ; community-based intervention ; diet ; home food availability ; home food environment ; sugar sweetened beverages ; fruit and vegetable intake ; Mediterranean diet ; Mediterranean diet pyramid ; sustainable diets ; environmental concerns ; nutrition ; food-based dietary guidelines ; migrants ; diabetes ; food habits ; culturally tailored diet ; transcultural mediator ; café ; green ambience ; Delphi method ; indicator design ; grain production ; spatial–temporal characteristic ; influencing factors ; the Huang-Huai-Hai Plain ; Crepis vesicaria L. subsp. taraxacifolia ; nutritional value ; phenolic profile ; chicoric acid ; antioxidant ; anti-inflammatory ; Brazil ; community restaurants ; food handlers ; food insecurity ; low-income ; COVID-19 ; families ; children ; food acquisition ; restaurants ; biofilms ; food microbiology ; dietary guidelines ; Mediterranean ; the USA ; Japan ; Argentina ; South Africa ; egg quality traits ; ginger ; immunity ; Japanese quail performance ; halal food performance ; availability ; healthy/nutritional factor ; accreditation ; clean/safe/hygiene factor ; trust ; attachment ; halal-friendly image ; retention ; muslim travelers ; Escherichia coli ; bacterial retention ; surface topographies ; meat exudate ; wipe cleaning ; conditioning film ; Cape Verde ; cereals ; metals ; dietary intake ; risk assessment ; Indigenous health ; food systems ; colonialism ; community-based ; participatory ; n/a ; dysphagia ; the elderly ; food products ; processing ; rheology ; texture ; capital endowment ; ecological cognition ; environment-friendly technology ; adoption level ; Hackman model ; environmental health ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
    Sprache: Englisch
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  • 39
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: In 2011, carbohydrates provided 63% of the dietary energy intake to the world’s population. Historically, carbohydrate-rich diets have been associated with good health and longevity but there has been a move away from traditional carbohydrate-rich diets, with refined carbohydrate taking much criticism for contributing to non-communicable disease. The aim of this Special Issue is to discuss the appropriate use of environmentally sustainable carbohydrate-rich foods in the modern diet in developing and developed countries in the context of prevention and treatment of non-communicable disease.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; satiety ; preload ; carbohydrate ; observational study ; body weight ; chronic disease risk ; postprandial ; isomaltulose ; qualitative ; glycaemic glucose equivalents ; mixed meal ; glycaemia ; obesity ; kiwifruit ; knowledge ; carbohydrates ; sugars ; timing ; sucrose ; CVD ; nutrition ; glycemia ; prebiotics ; intestinal biota ; glycemic response ; fibre ; T2DM ; low-carbohydrate diet ; ethnicity ; rice consumption ; activity ; fruit ; exercise ; discussion groups ; potato ; resistant starch ; pasta ; type 2 diabetes mellitus ; glycemic index ; vitamin C ; carbohydrate exchanges ; fructose ; glycemic load ; Japanese diet ; rice ; type 2 diabetes ; glycaemic response ; dietary pattern ; insulinaemia ; diabetes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 40
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of “selfishness”, based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these “silent” chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; parent-of-origin effects ; fluorescent in situ hybridization ; coverage ratio analysis ; n/a ; ribosomal DNA ; reactivation ; cytogenetics ; epigenetics ; heterochromatin ; interphase nucleus ; whole genome resequencing ; transmission ; grasshoppers ; genome instability ; dot-like (micro) Bs ; ?s ; B chromosome ; supernumerary elements ; transcription of heterochromatin ; maternal X chromosome ; supernumerary chromosome ; population analysis ; supernumerary ; repeat clusters ; extra chromosomes ; genes ; tandem repeats ; B morphotypes ; repetitive DNA ; repetitive elements ; DNA copy number variation ; chromosome polymorphism ; satellite DNA ; mammals ; maize B chromosome ; additional chromosomes ; inactivation ; drive ; B chromosomes ; FISH (fluorescence in situ hybridisation) ; organelle DNA ; Orthoptera ; origin ; supernumerary chromosomes ; karyotype evolution ; GISH (genomic in situ hybridisation) ; DNA composition ; de novo centromere formation ; genomics ; paternal X chromosome ; euchromatin degradation ; supernumerary chromosomal segments (SCS) evolution ; centromere ; sSMC ; Prospero autumnale complex ; next-generation sequencing ; Drosophila ; host/parasite interaction ; Apodemus peninsulae ; genome evolution ; evolution ; teleost ; chromosome evolution ; microdissected DNA probes ; controlling element ; mobile element ; RNA-Seq ; karyotypes ; karyotypic characteristics ; RepeatExplorer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 41
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: The authentication of foods and beverages is a very current topic of great interest for all the actors involved in the food chain, including the food industry, consumers, and food science researchers. Food authenticity covers many different aspects related to mislabeling, adulteration, and misleading claims about origin, production methods, or processing technologies. As many factors may affect the chemical composition of foods (e.g., geographical origin, variety or breed, conditions of cultivation, and breeding and/or feeding), the implementation of accurate, robust, and high-throughput analytical methods is needed to assess their authenticity and traceability and, consequently, guarantee their safety and quality in terms of organoleptic, nutritional, and bioactive characteristics. For these purposes, multiple analytical tools can be employed in combination with advanced chemometrics, such as spectroscopic and chromatographic techniques, DNA-based methods, and state-of-the-art omics approaches. In this context, in 2020, the journal Foods launched the Special Issue “Food Authentication: Techniques, Trends and Emerging Approaches” to gather research papers and review articles dealing with the development and application of analytical techniques and emerging approaches in food authentication. Considering the success and popularity of this earlier Special Issue, we will now release a second Special Issue comprising ten valuable scientific contributions, including one review article, one commentary article, and eight original research articles.
    Schlagwort(e): rapid authentication ; handheld Raman ; NIR ; fatty acid profile ; oil qualification ; coffee authenticity ; HPLC-UV ; HPLC-FLD ; fingerprinting ; chemometrics ; food adulteration ; chicory ; barley ; flours ; fourier-transform infrared (FT-IR) spectroscopy ; second-derivative spectrum ; red pepper powder ; geographical origin ; discriminant analysis ; SDS method ; Qiagen method ; polymerase chain reaction (PCR) ; multiple attribute decision making (MADM) analysis ; Aerodramus ; coffee ; fermentation ; gastrointestinal tract ; Kopi Luwak ; civet ; characterization ; Fourier-transform infrared spectroscopy ; cluster analysis ; Sherry vinegar ; spectralprint ; random forest ; support vector machine ; molecular traceability ; authentication ; agri-food ; molecular markers ; DNA barcoding ; isothermal amplification ; sequencing ; alkaline phosphatase determination ; PDO Pecorino Siciliano cheese ; raw milk determination ; vinegar ; protected designation of origin ; UV-Vis spectroscopy ; prediction ; sterols ; olive oil ; triterpenic dialcohols ; supported liquid extraction ; high performance liquid chromatography ; gas chromatography ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Sprache: Englisch
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  • 42
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Several epidemiological studies have demonstrated that oxidative stress is associated with a number of health disorders, including cardiovascular malfunction, certain types of cancer, diabetes mellitus, many other auto-immune diseases, and even ageing. The body possesses multiple mechanisms to counteract oxidative stress, which employ antioxidant compounds that are either naturally generated in situ (endogenous antioxidants) or externally supplied through food (exogenous antioxidants). These antioxidants are able to counteract oxidative stress, thanks to their ability to neutralize excess free radicals and protect the cellular lipids, proteins, and DNA from molecular damage. Exogenous antioxidants from the diet are of increasing interest because of their beneficial role in maintaining good health and in preventing chronic diseases. Indeed, a diet rich in dietary antioxidants, especially from fruits and vegetables, has been correlated with a successful prevention and lower incidence of several degenerative pathologies, including obesity, diabetes, cardiovascular diseases, and cancer. This Special Issue of Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature, examining the role of diets rich in antioxidant compounds in the prevention of chronic diseases and the characteristics of the antioxidants included in such diets.
    Schlagwort(e): QH301-705.5 ; antioxidants ; chronic diseases ; dietary supplementation ; human health ; prevention ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 43
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Biocontrol of plant diseases is considered one of the most important and current challenges of our society due to the need to look for eco-friendly alternatives to chemicals. Thus, research towards the biological control sensu lato [antagonist microorganisms, biostimulants, Induced Resistance (IR)] of plant diseases is an urgent demand for the agro-food sector of the Euroregion as well as for our society in the frame of the European Green Deal. Exploring different biocontrol tools as well as their combined effect against plant diseases is essential to generate knowledge on such topics to look for optimum management strategies in crop protection in the frame of organic and sustainable agriculture. Within this framework, this Special Issue of Plants brings together a collection of research papers on applied plant pathology and targeted reviews of biocontrol, including studies on antagonist microorganisms, biostimulants, and host resistance-inducers against plant diseases.
    Schlagwort(e): biological control agents ; biostimulation ; resistance host inducers ; sustainable agriculture ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 44
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Recent special issues in various journals have focused on “urban ecosystem services”. There is also an increasing amount of studies on “urban ecology”, “urban tree management”, “arboriculture”, “urban biodiversity”, and “ecosystem services” from wildland forests. This Special Issue aims to fill a void and focus on the socio-ecological diversity and the economic value of the ecosystem services from urban and peri-urban forests. Urban and peri-urban forests are tree dominated ecosystems in and near human settlements, while ecosystem services are the direct economic, social, and environmental benefits provided by their structural components and ecological functions.
    Schlagwort(e): QH301-705.5 ; GE1-350 ; Perceptions and attitudes ; Climate change ; Socio-ecological systems ; Ecosystem service tradeoffs ; Non-market valuation ; Urban forest structure and biodiversity ; Management and planning ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 45
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Outbreaks of crown-of-thorns starfish (Acanthaster spp.) are a major contributor to ongoing coral loss on reefs throughout the Indo-Pacific, thereby jeopardizing productivity and biodiversity of these important marine ecosystems. Controlling outbreak populations of Acanthaster spp. is considered one of the most promising strategies to halt or reverse widespread declines in live coral cover. Effective management of crown-of-thorns starfish is, however, conditional on improved understanding of their biology and ecology. While crown-of-thorns starfish are arguably the most extensively studied of any single coral reef species, there remain considerable gaps in our knowledge of their basic biology and ecology. This edited monograph presents the latest research and significant advances in understanding and managing outbreaks of crown-of-thorns starfish.
    Schlagwort(e): QH301-705.5 ; Coral reefs ; Habitat loss ; Disturbance ; Ecology ; Management ; Acanthaster spp. ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 46
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Alternative treatment modes for antibiotic-resistant bacterial pathogens have become a public health priority. Bacteriophages are bacterial viruses that infect and lyse bacterial cells. Since bacteriophages are frequently bacterial host species-specific and can often also infect antibiotic-resistant bacterial cells, they could represent ideal antimicrobials for fighting the antibiotic resistance crisis. The medical use of bacteriophages has become known as phage therapy. It is widely used in Russia, where phage cocktails are sold in pharmacies as an over-the-counter drug. However, no phage product has been registered for medical purposes outside of the former Soviet Union. The current Special Issue of Viruses contains a collection of papers from opinion leaders in the field who explore hurdles to the introduction of phage therapy in western countries. The articles cover diverse topics ranging from patent to regulatory issues, the targeting of suitable bacterial infections, and the selection and characterization of safe and efficient phage cocktails. Phage resistance is discussed, and gaps in our knowledge of phage–bacterium interactions in the mammalian body are revealed, while other articles explore the use of phages in food production and processing.
    Schlagwort(e): QH301-705.5 ; QR1-502 ; Q1-390 ; alginate ; abortive infection ; n/a ; bacterial resistance ; bacteriophages ; ATMP ; MALDI-MS ; adaptation ; Bacteriophage ; horizontal gene transfer ; adaptive immunity ; co-evolution ; Listeria ivanovii ; personalised medicines ; pH stability ; phage-human host interaction ; vB_SauM-fRuSau02 ; antimicrobial resistance ; phagodisinfection ; biofilm ; capsule depolymerase ; animal model ; phage cocktails ; Enterococcus ; cases report ; zoonosis ; resistance ; magistral formula ; experimental therapy ; Belgium ; phage therapy ; E. faecalis ; nontraditional antibacterial ; industrial phage application ; Democratic Republic of the Congo ; OrthoMCL ; Germany ; high-throughput sequencing ; antimicrobial ; infection ; antibiotic therapy ; Kayvirus ; phages ; Twortlikevirus ; bacterial disease ; human host ; Pseudomonas aeruginosa ; phage ; multidrug-resistant bacteria ; bacterial infection ; Salmonella Typhi ; rhamnopolysaccharide ; compassionate use ; crop production ; compounding pharmacy ; antimicrobial resistance (AMR) ; best practices ; bacteriophage efficacy ; phage sensitivity ; antibiotic-resistance ; antibiotic ; lysins ; PTMP ; Escherichia coli ; typhoid fever ; patent landscape ; phage preparation ; innate immunity ; anti-phage antibodies ; immunology ; Staphylococcus aureus ; global health ; clinical trial ; adsorption ; Brussels ; phage-resistance ; Galleria mellonella ; science communication ; history of science ; virus–host interactions ; foodborne illness ; prophage ; resistance management ; biofilms ; IND ; immunomodulation ; frequency of resistance ; capsule ; gastrointestinal tract ; phage-host interactions ; disinfection ; production ; bacteriophage therapy ; bacteriophage ; Staphylococcus ; magistral preparation ; extended-spectrum beta lactamases (ESBL) ; Viral proteins ; antibiotic resistance ; genomics ; phage biocontrol ; therapy ; target selection ; viral genomes ; evolution ; pharmaceutical paradigm shift ; personalized medicine ; pharmaceutical legislation ; food safety ; regulation ; virulence ; developing countries ; infectious disease ; regulatory framework ; sustainable agriculture ; Klebsiella pneumoniae ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 47
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Fruits and vegetables are important sources of nutrients, such as vitamins, minerals, and bioactive compounds, and provide many health benefits. However, due to non-optimal post-harvest management, large quantities of fresh or fresh-cut fruits and vegetables experience a decline in their quality and nutritional value before they reach the consumer. This Special Issue covers technologies for the harvesting, handling, and storage of vegetables, including storage strategies such as active packaging, edible coatings, the application of nanotechnology in the post-harvest of vegetable crops, and others, with the aim of improving the shelf-life of fresh and fresh-cut fruits and vegetables.
    Schlagwort(e): fresh walnut ; total phenols ; frozen storage ; fatty acid ; antioxidant enzyme ; fruit storage ; antioxidant capacity ; phenolic compounds ; gene expression ; Fragaria × ananassa Duch. ; Sabrosa ; ripening stage ; headspace solid phase microextraction (HS SPME GC/MS) ; HPLC-MS/MS principal component analysis ; fresh-cut cauliflower ; storage period ; calcium chloride ; temperature ; factor analysis ; quality ; table grapes ; optimal harvesting ; technological maturity ; phenolic maturity ; non-destructive tools ; Multiplex® 3 ; pectin-based coating ; quality attributes ; fresh-cut carrot ; respiratory activity ; carotenoids and phenolic compounds ; lemon byproduct ; antioxidant ; e-nose ; ATR-FTIR ; image analysis ; multivariate analysis ; Barhi dates ; Phoenix dactylifera ; chitosan ; orange peel ; olive cake ; coating ; scanning electron microscopy ; surface structure ; antifungal active packaging ; raspberry ; green tea extract ; rosemary extract ; citrus ; intelligent logistics ; modeling ; orange ; postharvest ; chilling injury ; storage ; melatonin ; 1-MCP ; oregano ; vacuum packaging ; Allium cepa ; Rhus coriaria ; refrigeration ; mango fruit ; melatonin treatment ; cold storage ; decay ; physiological and metabolic processes ; goji berries ; shelf-life ; postharvest quality ; sensorial attributes ; freshness ; active packaging ; cold plasma ; dipping ; E-nose ; high hydrostatic pressure ; innovative postharvest technologies ; pulsed electric field ; vacuum impregnation ; near-infrared spectroscopy ; Pleurotus eryngii ; king oyster mushroom ; quality influential factors ; preservation ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 48
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: This Special Issue collects research on and applications of the relationship between food, nutrition, and databases. The development of databases of nutrients, bioactive compounds, and metabolites are key tools for human health and public nutrition and represent resources for a wide range of applications in food, pharmaceutical, nutraceutical, epidemiology, and medicinal areas. The current research trends are highlighted.
    Schlagwort(e): plant sterols ; database ; Polish population ; supermarket packaged foods ; private labels ; generic labels ; branded labels ; health star rating ; sugar ; sodium ; healthiness ; price ; public health policy ; food data ; natural substances ; health promotion ; sustainable foods ; national food composition databases ; one health ; nutritional knowledge ; eight-year-old students ; official control ; school canteen ; food composition database ; nutrient pattern ; nutrient composition ; principal component analysis ; food-based dietary guideline ; salt intake ; South Africa ; salt content ; nutritional claims ; nutrient profile/profiling models ; changes in sodium content ; food database ; public health ; industrially-produced trans fatty acids ; Elaidic acid ; Linolelaidic acid ; traditional dishes ; Arabic sweets ; market foods ; Lebanon ; n/a ; fast food ; total sugars ; population health ; food environments ; meal combos ; food standardization ; nutrients ; bioactive compounds ; personalized nutrition ; saccharin ; sucralose ; gut microbiota ; acceptable daily intake ; short-term studies ; long-term studies ; short-chain fatty acids ; cognitive impairment ; cognitive decline ; nutritional care ; hospitalized patient ; elderly patient ; EuroFIR AISBL ; food data banks ; standardization ; harmonization ; interoperability ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
    Sprache: Englisch
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  • 49
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: The survival of plants under stressful environments requires the study of the mechanisms that help in reversing the adverse impacts of reactive oxygen species (ROS) excessively generated under these conditions. Understanding the mechanisms helps in adopting strategies to induce such mechanisms for the better acclimation of plants. These ROS, if not scavenged, cause damage of cellular components, including lipids, proteins, nucleic acids, and metabolites, and, in extreme cases, even the death of cells in plants. Confronted with abiotic stress, there is an initial elevation in ROS that activates redox signaling to initiate defense in plants through the activation of antioxidant activity. The improvement in the capacity of antioxidant machinery is one of the essential strategies with which to develop tolerance and relieve the pressure of abiotic-stress-induced oxidative changes for the survival of plants. This reprint provides knowledge on the following aspects: Impact of abiotic stress factors and the response of antioxidant machinery to changing abiotic stress conditions, as well as strategies with which to strengthen antioxidant machinery for the survival of plants; Strategies to improve the tolerance mechanisms of plants against abiotic stress factors; Roles and the mechanisms of the plant signaling molecules/growth modifiers/mineral nutrients/hormones/other elicitors in relieving the impacts of abiotic stresses; The utilization of approaches such as genomics, metabolomics, transcriptomics, proteomics, ionomics, and nutiomics to strengthen antioxidant machinery and make plant life easier under abiotic stress conditions.
    Schlagwort(e): tomato ; photosynthesis ; root growth ; oxidative damage ; melatonin ; drought ; gene expression ; toxic metals/metalloid ; nanoparticles ; phytohormones ; phytoremediation ; reactive oxygen species ; antioxidant enzymes ; heavy metal stress ; ubiquitination ; protein degradation ; gas exchange features ; osmotic adjustment ; water deficiency ; water-use-efficiency ; antioxidant defense ; arabidopsis ; bioinformatic analysis ; SlBAG genes ; SlBAG9 ; Solanum lycopersicum ; antioxidants ; oxidative stress ; marker-free transgenic rice ; mature seed-derived calli ; pea DNA helicase 45 ; salinity stress tolerance ; ethylene response factor ; flooding stress ; metallothionein ; monodehydroascorbic acid reductase ; resistant cultivar ; respiratory burst oxidase ; sensitive cultivar ; biochemical metabolites ; plant growth ; stigmasterol ; wheat ; polyamine ; iron-deficiency ; transcriptomics ; BAG9 ; Hsps ; thermotolerance ; ethylene ; hydrogen sulfide ; nitric oxide ; rice ; Arabidopsis ; metabolome ; ROS ; rohitukine ; ascorbate peroxidase ; catalase ; hydrogen peroxide ; NADP dehydrogenases ; NADPH oxidase ; salt stress ; superoxide dismutase ; seed priming ; spermine ; chromium ; S1fa transcription factor ; cell wall ; yeast ; antioxidant enzyme ; heat stress ; betaine ; seed germination ; physiology ; biochemistry ; Hibiscus cannabinus ; physiological changes ; bioactive constituents ; antioxidant capacity ; bioactive molecules ; carotenoids ; flavonoids ; osmotic stress ; phenolic acids ; secondary metabolites ; exogenous spermidine ; lettuce ; transcriptome ; vanadium stress ; sweet potato ; antioxidant defense system ; stomatal traits ; antioxidant systems ; Cu stress ; leucine ; nitrogen metabolism ; peach ; polyamine uptake protein ; Put2 ; ascorbate ; Dittrichia ; glutathione ; thallium toxicity ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 50
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: This reprint represents a collection of scientific papers belonging to a Special Issue of Antioxidants entitled "Advances in the Astonishing World of Phytochemicals: State-of-the-Art for Antioxidants". Several studies have revealed that plants are a source of a plethora of bioactive compounds, such as phytohormones, glycosides, terpenoids, alkaloids, phenolic compounds, and essential oils, with a strong potential impact in the fields of pharmaceutics and agriculture. These phytochemicals represent a valuable weapon that plants use in self-defense in order to counteract the effects of abiotic stress disturbing the delicate equilibrium between the generation of reactive oxygen species (ROS) and antioxidant defense systems. In recent years, interest in this area of research has been increasing due to the multifaceted properties of natural compounds with antioxidants having anticancer, anti-inflammatory, and antimicrobial activity. Therefore, understanding the underlying mechanism of their action is crucial to establishing their real potential in applied sciences. This reprint focuses on the most recent advances in the study of antioxidant molecular mechanisms activated by phytochemicals, with potential pharmacological and agricultural applications. We thank all the authors for their contribution to the research topic of this reprint and all editorial staff for their valuable support.
    Schlagwort(e): antioxidant response element (ARE) ; Nrf2 signaling pathway ; bioactive byproducts ; proanthocyanidins ; oxidative stress mechanisms ; thinned apples ; polyphenols ; anti-oxidant ; anti-inflammatory ; NRF2 ; NF-κB ; proteomics ; antioxidants ; acetylcholinesterase ; 1,1-diphenyl-2-picrylhydrazyl ; HPLC ; medicinal plants ; oxidative stress ; cytotoxicity ; hepatoprotective effects ; HeLa cancer ; inflammation ; mass spectrometry ; oxidation ; prostate cancer ; phytochemical ; phenolic acids ; phenolic mixtures ; interaction effect ; antioxidant activity ; FRAP ; ORAC ; Achillea millefolium ; yarrow extract ; H. pylori ; supercritical anti-solvent fractionation ; anti-inflammatory activity ; antibacterial activity ; A. gangeticus ; protein and dietary fiber ; minerals ; phytochemicals ; HPLC-UV DPPH ; ABTS+ ; PA profiles ; NaCl ; Mexican Gordolobo ; supercritical CO2 extraction ; fatty acids ; biomass valorization ; mountain pepper ; rosella ; strawberry gum ; lemon aspen ; flavonoids ; anthocyanins ; bioavailability ; LC-MS/MS ; microalgae ; exopolysaccharides ; phycoerythrin ; biocompatibility ; wound healing ; Echinacea purpurea extracts ; fractions ; phenols/carboxylic acids ; alkylamides ; human primary macrophages ; pressurized liquid extraction ; seaweeds ; green extraction technique ; bioactive compounds ; functional ingredients ; food packaging ; future trends ; tomato-based products ; metabolic syndrome ; HFD ; antioxidant capacity ; phytonutrients ; yarrow ; fragmentation pathway ; electrospray ionization ; secondary metabolites ; horseradish ; mass spectra ; kaolinite ; phyto-carrier system ; phytocompounds ; methyl gallate ; autophagy ; apoptosis ; p53 ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 51
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: The school of thought surrounding the urban ecosystem has increasingly become in vogue among researchers worldwide. Since half of the world’s population lives in cities, urban ecosystem services have become essential to human health and wellbeing. Rapid urban growth has forced sustainable urban developers to rethink important steps by updating and, to some degree, recreating the human–ecosystem service linkage.Assessing as well as estimating the losses of ecosystem services can denote the essential effects of urbanization and increasingly indicate where cities fall short. This second book on urban ecosystem services contains 11 thoroughly refereed contributions published within the Special Issue “Urban Ecosystem Services II: Toward a Sustainable Future”. The book addresses topics such as cultural ecosystem services, green infrastructure, urban trees, urban green spaces, and more. The contributions highlight current knowledge, gaps, and future research with the focus on building a sustainable future.
    Schlagwort(e): urban biodiversity ; urban watersheds ; Bogota Colombia ; corruption ; Unwillingness to Invest ; natural capital ; blue-green infrastructure ; urban environmental challenges ; Global South ; tropical cities ; urban forestry ; cultural ecosystem services ; public survey ; tree maintenance ; urbanization ; birds ; ecosystem services ; survival ; adaptations ; traits ; land-based financing ; land monetisation ; policy ; infrastructure ; Sustainable Development Goals ; compensation measures ; urban resilience ; urban development ; impact assessment ; cityscape visual perception ; green infrastructure ; linear parks ; sustainable landscape planning ; tram lanes ; Warsaw ; ecosystem service value ; farmland loss ; construction land expansion ; remote sensing ; landscape architecture ; design ; evaluation ; urban ecosystem services ; urban tree planting ; i-Tree Canopy ; Office for National Statistics ; health damage costs ; United Kingdom ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Sprache: Englisch
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  • 52
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Estrogen receptors (ERs) are typical members of the superfamily of nuclear receptors that mainly function as ligand-inducible transcription factors that bind chromatin, as homodimers, at specific response elements. A tight reciprocal coupling between rapid ‘non-genomic’ and ‘genomic’ ER actions may also occur in many physiological processes. ERs have long been evaluated for their roles in controlling the expression of genes involved in vital cellular processes such as proliferation, apoptosis, and differentiation. Therefore, given the various and pleiotropic functions of ERs, the dysregulation of their pathways contributes to several diseases such as the hormone-dependent breast; endometrial and ovarian cancers; and neurodegenerative diseases, cardiovascular diseases, and osteoporosis. In this printed edition of the Special Issue, “Molecular Pathways of Estrogen Receptor Action”, promising results on understanding the mechanisms underlying ER-mediated effects in various pathophysiological processes are represented, covering different roles of ER pathways in the tumorigenesis, the resistance to endocrine therapy, the dynamics of 3D genome organization, and cross-talk with other signaling pathways. This Special Issue also provides insight into the emerging roles of estrogen-signaling pathways in lung cancer, the tumor microenvironment, and the immune system.]
    Schlagwort(e): QH301-705.5 ; Estrogens and estrogen receptors ; Cell signaling ; Physiopathology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 53
    Publikationsdatum: 2024-04-05
    Beschreibung: While international efforts in the development of short rotation woody crops (SRWCs) have historically focused on the production of biomass for bioenergy, biofuels, and bioproducts, research and deployment over the past decade has expanded to include broader objectives of achieving multiple ecosystem services. In particular, silvicultural prescriptions developed for SRWCs have been refined to include woody crop production systems for environmental benefits such as carbon sequestration, water quality and quantity, and soil health. In addition, current systems have been expanded beyond traditional fiber production to other environmental technologies that incorporate SRWCs as vital components for phytotechnologies, urban afforestation, ecological restoration, and mine reclamation. In this Special Issue of the journal Forests, we explore the broad range of current research dedicated to our topic: International Short Rotation Woody Crop Production Systems for Ecosystem Services and Phytotechnologies
    Schlagwort(e): QH301-705.5 ; Q1-390 ; SD1-669.5 ; rhizospheric soil ; allocation ; acidic soil ; abandoned farmland ; carbon sequestration ; bioenergy ; mycorrhizal fungi ; leaf area index ; foliar nutrient and metal concentration ; aboveground biomass ; inoculation ; stocking level ; site reclamation ; willow ; Salix ; spacing trial ; agricultural field experiment ; Populus ; Populus canadensis ; species variation ; ecosystem services ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 54
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Environmental issues have attracted great attention with the pursuit of a high quality of life, and the effective removal of environmental pollutants is a great challenge today. This includes two topics: one is to remove the pollutants produced post-treatment, and the other is to synthesize chemicals by a green route, avoiding producing pollutants in the process.Catalytic technology is an effective way to solve environmental problems, which can facilitate the conversion of pollutants to nontoxic or even useful chemicals. Thus, this reprint focuses on resolving the environmental problems by a catalysis technology, including photocatalysis, thermocatalysis, and electrocatalysis. Research works relating to the catalytic removal of pollutants or the catalytic synthesis of chemicals by a green route are reported.
    Schlagwort(e): antibiotics ; photocatalytic degradation ; degradation mechanism ; photocatalysts ; ROS ; solid Fe resources ; recycling ; CO oxidation ; propane dehydrogenation ; dendrimer-like silica nanoparticle support ; Pt/Sn ratios ; selective oxidation ; benzaldehyde ; nanometer-size catalyst ; MOFs material ; graphitic carbon nitride ; metal oxides ; heterojunctions ; synthesis ; photocatalytic applications ; photocatalysis ; photodegradation ; carbon nitride ; phase junction ; MOF ; electrocatalysis ; electronic structure ; flow cell ; large current density ; Co3O4/Bi12O17Cl2 ; heterojunction ; Rhodamine-B ; Bisphenol-A ; oxygen vacancy ; exciton effect ; Bi2MoO6 ; sodium pentachlorophenate ; visible light ; N-doped TiO2 ; Bi2WO6 ; composite photocatalyst ; benzene degradation ; thermoactivation ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Sprache: Englisch
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  • 55
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Fungal natural products have made important contributions to the history of human civilization. Mr. Liu Jikai has had a significant influence on the field of chemistry in fungal natural products, leading a large number of Chinese scholars engaged in related research. We would like to take this opportunity to thank Mr. Liu Jikai for his efforts on fungal natural products chemistry and hope that all colleagues will make great progress for the future.
    Schlagwort(e): sesquiterpenoids ; fungus ; structures ; structural diversity ; biological activity ; synthesis ; heterologous expression ; PKS-NRPS ; ilicicolin H ; shunt metabolite ; Trichoderma reesei ; Craterellus ordoratus ; isolation and structural elucidation ; immunosuppressive activity ; propionyl-CoA metabolism ; modular polyketide synthase ; propionyl-CoA carboxylase ; Bipolaris sp. ; kiwi-associated fungus ; sesquiterpenoid ; xanthone ; anti-pathogenic microorganism activity ; monomeric sorbicillinoids ; bisorbicillinoids ; trisorbicillinoids ; hybrid sorbicillinoids ; fungi ; occurrence ; biological activities ; verrucosidins ; Penicillium cellarum ; glucose uptake-stimulating activity ; molecular networking ; endophytic fungi ; secondary metabolites ; structural feature ; drug discovery ; Phaeosphaeria sp. ; secondary metabolite ; polyketide ; AChE inhibitor ; biosynthetic pathways ; diterpenes ; isolation ; structure ; biosynthesis ; biosynthetic pathway crosstalk ; natural product ; biosynthetic gene cluster ; bioactivity ; Ganoderma applanatum ; lanostane triterpenoid ; Mosher’s method ; anti-adipogenesis activity ; structure–activity relationship ; PKS ; waste valorization ; microbial cell factory ; phenalenones ; cancer ; casein kinase ; CK2 inhibitor ; molecular docking ; Asteromyces cruciatus ; marine fungi ; polyketides ; sortase A ; chlore-containing metabolites ; Staphylococcus aureus ; antibacterial activity ; biofilm formation ; Boeremia exigua ; Fritillaria hupehensis ; eremophilanes ; boeremialanes ; anti-inflammatory ; NO production inhibition ; Ganoderma australe ; triterpene ; 20(22)E configuration ; PGME method ; balanol biosynthesis ; protein kinase C inhibitor ; Zn2Cys6 ; regulator BlnR ; medium optimization ; fermentation ; Tolypocladium ophioglossoides ; sorbicillinoids ; Acremonium chrysogenum ; structure elucidation ; DPPH radical scavenging activity ; antimicrobial compounds ; marine natural products ; endophytic fungus ; Phomopsis ; cytochalasan ; antimigratory activity ; Sparticola triseptata ; ECD–TDDFT ; antiproliferative ; cytotoxic ; actin inhibitors ; sulfur ; plant endophyte ; n/a ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 56
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Ecological patterns are the manifestation of salient feedback between species and the environment, considering both the natural and built environment. Mapping this dynamical feedback over space and time means extracting the structural and functional networks of habitats and species whose nexus defines the systemic function that can be preserved and enhanced via protection and eco-engineering solutions. The key is to sense the ecological collective behavior that is salient for quantitative ecosystem assessment, forecasting, and engineering. This Topic aims to highlight data, methods, inferred processes, and solutions about collective ecological patterns at multiple scales and for diverse ecosystems. The core objective is to stress the crucial importance of ecological information and monitoring for detailed and quantitative assessment of ecosystems on which future nature-based solutions can be developed considering climate risks and population values.
    Schlagwort(e): Biodiversity ; Ecosystems ; Biocomplexity ; Sensing ; Networks ; Information ; Environment ; Ecology&nbsp ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Sprache: Englisch
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  • 57
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The majority of carbon stored in the soils of the world is stored in forests. The refractory nature of some portions of forest soil organic matter also provides the slow, gradual release of organic nitrogen and phosphorus to sustain long term forest productivity. Contemporary and future disturbances, such as climatic warming, deforestation, short rotation sylviculture, the invasion of exotic species, and fire, all place strains on the integrity of this homeostatic system of C, N, and P cycling. On the other hand, the CO2 fertilization effect may partially offset losses of soil organic matter, but many have questioned the ability of N and P stocks to sustain the CO2 fertilization effect.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; SD1-669.5 ; polyphenols ; aluminum accumulator ; near natural forest management ; chloroform fumigation extraction ; soil structure ; soil enzymes ; manure pelleting ; microbial biomass ; Oxisol ; biolability ; soil nutrients ; second production cycle ; PLFA ; pyrolysis ; Eucalyptus sp. ; Cunninghamia lanceolata plantation ; carbon ; the Three Gorges Reservoir ; revegetation ; carbon distribution index ; climate change ; seasons ; annual increment average ; topography ; humic substances ; litter N ; soil fertility ; climate zone ; nutrient cycling ; Daxing’an Mountains ; carbon mineralization ; nitrification ; 31P nuclear magnetic resonance spectroscopy (31P NMR) ; organic matter ; throughfall ; forest soil ; dissolved organic carbon (DOC) ; P species ; stoichiometric homeostasis ; dissolved organic matter (DOM) ; soil organic matter fraction ; variable-charge soils ; ammonium ; nitrate ; soil degradation ; soil P fractions ; seasonal trends ; ammonia-oxidizing bacteria ; nitrogen dynamics ; net primary productivity ; soil microbial communities ; beech forests ; soil pH ; wood volume ; temperature ; northern temperate ; multilevel models ; Pinus massoniana plantation ; ammonia-oxidizing archaea ; P stock ; stand density ; P resorption efficiency ; forest types ; soil greenhouse gas flux ; enzyme activities ; soil N ; alpine forest ; moisture gradient ; climate ; climatic factors ; soil available phosphorus ; microbial activity ; soil available nitrogen ; leaf N:P ratio ; stemflow ; Chamaecyparis forest ; charcoal ; gross nitrogen transformations ; principal component analyses ; information review ; manuring ; stand age ; tree-DOM ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 58
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The emergence of marine and freshwater toxins in geographical areas where they have never been reported before is a concern due to the considerable impact on (sea)food contamination, and consequently, on public health. Several groups of marine biotoxins, in particular tetrodotoxins, ciguatoxins, and palytoxins, are included among the relevant marine biotoxins that have recently emerged in several coastal areas. A similar situation has been observed in freshwater, where cyanobacterial toxins, such as microcystins, could end up in unexpected areas such as the estuaries where shellfish are cultivated. Climate change and the increased availability of nutrients have been considered as the key factors in the expansion of all of these toxins into new areas; however, this could also be due to more intense biological invasions, more sensitive analytical methods, or perhaps even an increased scientific interest in these natural contaminations. The incidences of human intoxications due to the consumption of seafood contaminated with these toxins have made their study an important task to accomplish in order to protect human health. This Special Issue has a focus on a wide variety of emerging biotoxin classes and techniques to identify and quantify them.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; n/a ; C-CTX-1 ; non-targeted analysis ; ciguatera fish poisoning ; suspects screening ; neurodegeneration ; adaptation ; LC-HRMS ; paralytic shellfish toxins ; LC-MS/MS ; animal toxins ; identification ; method characterization ; caribbean ciguatoxins ; oral toxicity ; water flea ; quorum sensing ; eutrophication ; beta-methyl-amino-l-alanine ; dynamics simulation ; thermal water ; spent medium ; Microcystis ; Gambierdiscus ; gambierdiscus ; whole genome sequencing ; palytoxin ; conotoxin ; ovatoxins ; cyanobacterial toxin ; BMAA ; Ciguatera fish poisoning ; Rastrineobola argentea ; calcium-activated K+ ion channel ; toxicity equivalence factor ; NMR spectroscopy ; N2a ; PPIA ; marine biotoxins ; Daphnia magna ; ELISA ; disulfide-rich peptide ; food chain ; ShK-like peptide ; voltage-gated K+ ion channel ; targeted analysis ; Chinese yellow catfish ; marine ; macaronesia ; neuroblastoma bioassay ; marine toxins ; acute toxicity ; algal–bacterial relationship ; mass spectrometry ; tetrodotoxins ; saxitoxin ; toxicology ; cationization ; seafood safety ; evolution ; cyanotoxins ; toxin genes ; zoantharian ; spatial variability ; dopaminergic neurons ; tetrodotoxin ; bivalve mollusks ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
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  • 59
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Tea, made from the leaves of the Camellia senenisis plant, is the second most consumed beverage worldwide after water. Accumulating evidence from cellular, animal, epidemiological and clinical studies have linked tea consumption to various health benefits, such as chemoprevention of cancers, chronic inflammation, heart and liver diseases, diabetes, neurodegenerative diseases, etc. Although such health benefits have not been consistently observed in some intervention trials, positive results from clinical trials have provided direct evidence supporting the cancer-protective effect of green tea. In addition, numerous mechanisms of action have been suggested to contribute to tea’s disease-preventive effects. Furthermore, effects of the processing and storage of tea, as well as additives on tea’s properties have been investigated.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; cell cycle arrest and apoptosis ; neuroblastoma ; salivary ?-amylase activity ; cancer apoptosis ; yaupon holly ; bioaccessibility ; fracture ; p53 ; tea ; Liubao tea ; BE(2)-C ; matrix metalloproteinase-1 (MMP-1) ; catechin ; renal stone ; oxalate ; protein expression ; 67LR ; Alzheimer’s disease ; EGCG ; nutraceutical ; diseases ; anti-oxidant ; heme oxygenase-1 ; polyphenol ; anxiety ; matcha ; ERCC1/XPF ; neuro-sphere ; tea consumption ; theanine ; Rosmarinic acid ; yerba mate ; hypercalciuria ; gene expression ; microbiota ; cohort study ; histone deacetylase 2 (HDAC2) ; guayusa ; nuclear factor erythroid 2-related factor 2 (Nrf2) ; DNA repair ; mRNA expression ; caffeine ; chemoprevention ; cisplatin ; 6-OH-11-O-hydroxyphenanthrene ; adrenal hypertrophy ; hepatic damage ; anti-photoaging ; cell death ; green tea ; kudingcha ; suberoylanilide hydroxamic acid (SAHA) ; epigallocatechin gallate (EGCG) ; stress-reduction ; calcium oxalate monohydrate ; Camellia sinensis ; chemoresistance ; tea polyphenols ; green tea polyphenols ; green tea catechins ; N-MYC ; cancer ; epigallocatechin-gallate (EGCG) ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: image/jpeg
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  • 60
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: The exposure of animals to environmental stresses (restraint, bad housing conditions, irradiation, pollution, diseases, and heat stress) and endogenous stresses (metabolic and physiological disorders) can seriously disrupt the redox homeostasis, leading to impairments in animals’ health and overall performance. Under these circumstances, the self-antioxidant defense system may not be enough to neutralize ROS effects. In this context, the utilization of an exogenous source of antioxidants, mainly dietary sources, may present an effective and cost-effective solution. There are a plethora of substances, either naturally occurring or synthesized (organic acids, minerals, vitamins, hormones, and specific feed additives originating from plants such as essential oils and polyphenols), known for their antioxidant activity, that can be used to maintain adequate redox status in animals in order to preserve their well-being and/or productivity. This area of research still needs more investigations in order to clearly elucidate the effective antioxidant substances that could be used in practical applications, with an emphasis on their biological mechanisms during different physiological conditions and health statuses. We intend to bring together current research concerning the role of antioxidant substances either from natural sources or those synthesized for improving animal production, reproduction, health, and welfare.
    Schlagwort(e): antinutrient ; enzyme ; fermentation ; fiber ; gut health ; microbiota ; meta-analysis ; poultry ; prebiotic ; antioxidants ; growth ; heat stress ; rabbit ; selenium ; spirulina ; zinc ; broiler ; dietary protein level ; phytogenic feed additive ; growth performance ; immune response ; exercise ; endurance ; undenatured type II collagen ; anti-inflammatory ; cardiac injury markers ; oxidative stress ; histopathology ; Bcl-2 ; Bax ; TGF-β1 ; date palm (pollen extract) ; doxorubicin ; nitrocompounds ; nitropropanol ; nitroethanol ; biochemical parameters ; oregano essential oil ; temperature ; sea bass ; cornelian cherry extract ; glucose transporter ; gene expression ; oxidative biomarker ; chicken ; cyclic heat stress ; Spirulina platensis ; redox status ; serum metabolites ; blood hematology ; meat quality ; fipronil ; boswellic acid ; PCNA ; semen ; fertility-related markers ; Oreochromis niloticus ; antioxidant ; hematology ; nitric oxide ; lysozyme ; copper toxicity ; vitamin C ; vitamin E ; hematological parameters ; phytogenic ; phenols ; antimicrobial activity ; immunity ; phenolic antioxidant ; olive oil ; caprine ; spermatozoa ; Bayesian inference ; Duroc breed boars ; biochemistry ; blood parameters ; feeding time ; correlation coefficients ; Turraea fischeri ; polyphenolics ; semen cryopreservation ; sperm ultrastructure ; antioxidant biomarker ; apoptosis ; nano particles ; performance ; blood ; pathogens ; quails ; carcass traits ; blood biochemical constituents ; abdominal fat color ; meat fatty acid profile ; liver histology ; broilers ; Eimeria tenella ; broiler chickens ; oocyst shedding ; volatile fatty acids ; feed efficiency ; cecal health ; active yeast ; antioxidant status ; nutrient density ; trace element ; laying hen performance ; high temperature ; inflammation ; cryopreservation ; tannin ; polyphenols ; semen additives ; carcass ; fructooligosaccharide ; haemato-biochemical parameters ; cecal microbiota ; propolis ; bee pollen ; productive performance ; fertility ; Holstein ; folic acid ; pregnancy ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences
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  • 61
    Publikationsdatum: 2024-04-05
    Beschreibung: Integrative omics of plants in response to stress conditions play more crucial roles in the post-genomic era. High-quality genomic data provide more deeper understanding of how plants to survive under environmental stresses. This book is focused on concluding the recent progress in the Protein and Proteome Atlas in plants under different stresses. It covers various aspects of plant protein ranging from agricultural proteomics, structure and function of proteins, and approaches for protein identification and quantification.
    Schlagwort(e): QH301-705.5 ; QK1-989 ; Q1-390 ; phosphoproteomics ; GLU1 ; somatic embryogenesis ; CHA-SQ-1 ; nitrogen fertilizer ; chilling stress ; differentially abundant proteins ; ATP synthase ; photosynthetic parameters ; photosynthesis ; constitutive splicing ; phosphorylation ; Jatropha curcas ; plants under stress ; postharvest freshness ; Alternanthera philoxeroides ; rubber latex ; Millettia pinnata ; molecular and biochemical basis ; filling kernel ; drought stress ; comparative proteomic analysis ; domain ; micro-exons ; phylogeny ; phos-tagTM ; E. angustifolia ; root cell elongation ; ABA ; pollen abortion ; lncRNA ; transcriptome ; radish ; redox homeostasis ; Nelumbo nucifera ; sugar beet ; shotgun proteomics ; proteomes ; high-temperature stress ; post-genomics era ; model plant ; salt tolerance ; miRNA ; wheat ; physiological response ; stress ; visual proteome map ; transcriptional dynamics ; leaf ; maize ; Dunaliella salina ; phosphatidylinositol ; S-adenosylmethionine decarboxylase ; Gossypium hirsutum ; flavonoid biosynthesis ; phosphatase ; wood vinegar ; heat shock proteins ; silicate limitation ; purine metabolism ; natural rubber biosynthesis ; ancient genes ; cotton ; rubber grass ; abiotic stress ; heat stress ; maturation ; low-temperature stress ; molecular basis ; transcriptome sequencing ; ROS scavenging ; widely targeted metabolomics ; transdifferentiation ; seed development ; alternative splicing ; cultivars ; inositol ; salt stress ; chlorophyll fluorescence parameters ; proteome ; carbon fixation ; AGPase ; transcript-metabolite network ; molecular mechanisms ; Triticum aestivum L. ; Zea mays L. ; ROS ; label-free quantification ; woody oilseed plants ; heat-sensitive spinach variety ; MIPS ; quantitative proteomics ; regulated mechanism ; two-dimensional gel electrophoresis ; potassium ; glutathione ; Salinity stress ; integrated omics ; diatom ; ATP synthase CF1 alpha subunit (chloroplast) ; root ; proteome atlas ; brittle-2 ; mass spectrometry ; genomics ; Taraxacum kok-saghyz ; cytomorphology ; proteomics ; arbuscular mycorrhizal fungi ; signaling pathway ; proteomic ; loss-of-function mutant ; rice ; seedling ; wucai ; leaf sheath ; root and shoot ; antioxidant enzyme ; exon-intron structure diversity ; isobaric tags for relative and absolute quantitation ; regulation and metabolism ; concerted network ; drought ; heat response ; VIGS ; iTRAQ ; nitrogen use efficiency (NUE) ; stem ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 62
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: This reprint contains 12 high-quality original research papers by 74 authors from 17 countries on 3 continents: Asia (China, Indonesia, Malaysia, and Russia), Europe (Bulgaria, the Czech Republic, Germany, Portugal, Romania, Slovakia, Slovenia, Sweden, Ukraine, and the United Kingdom), and North America (USA). These papers were published in a Special Issue, “Performance and Modification of Wood and Wood-Based Materials”, of the journal Forests. They provide examples concerning conventional and novel modification processes of wood and wood-based materials, their improved/modified properties, and their relevant applications.
    Schlagwort(e): heat treatment ; Chinese fir ; TD-NMR ; free water ; bound water ; MC ; birch wood ; spent engine oil ; water resistance ; biostability ; dimensional stability ; black alder ; birch ; color ; varnish system ; surface pre-treatment ; sanding ; thermal compression ; artificial aging ; wood plastic composite ; rubberwood ; polyethylene terephthalate ; silica ; thermo-hydro-mechanical densification ; Scots pine ; creep compliance ; thermal modification ; resin impregnation ; wood ; Maillard reaction ; thermal/chemical treatment ; mechanical properties ; infrared spectroscopy ; biological properties ; thermo-hydro-mechanical treatment ; molecular dynamics ; wood cellulose ; Acacia hybrid ; fast-growing ; copper chrome arsenic ; physical and mechanical properties ; coir fiber ; alkali treatment ; parameter optimization ; black locust wood ; ThermoWood process ; colour ; extractives ; chemical changes ; FTIR spectroscopy ; thermal densification ; plywood properties ; wood veneers ; Eucalyptus urograndis ; Chrysoporthe deuterocubensis ; infection classes ; chemical analysis ; FTIR analysis ; fungal decay ; termite attack ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
    Sprache: Englisch
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  • 63
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The Special Issue “Extractable and Non-Extractable Antioxidants” gives an updated view on antioxidants—both in their extractable and non-extractable form—in the different food groups, their products thereof, and food preparations as well as byproducts and biomass waste. The potential beneficial properties of these compounds and nutraceutical formulations are described in the various studies covered in this Special Issue.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; biorefinery ; polyphenols ; polymerization ; n/a ; black teas ; nutrient ; ultrasound assisted extraction ; cyclodextrin ; HPLC-ESI/MS ; legumes ; degradation ; LC-ESI-Q-TOF-MS ; antioxidant activity ; forest residues ; multivariate analysis ; bio-based ; chemometrics ; extractable polyphenols ; extractable compounds ; pre-column HPLC method ; Cagnulari marc ; antioxidant capacity ; flour ; total polyphenol content (TPC) ; digestibility ; ferric reducing antioxidant power (FRAP) ; natural antioxidants ; dietary assessment. ; eggplant ; antioxidant ; botanicals ; anthocyanins ; trans-cinnamaldehyde ; anti-inflammation ; cereals ; functional ingredient ; food composition database ; agglomerative hierarchical clustering ; circular economy ; fermentation ; Aloysia triphylla ; Naviglio Extractor® ; flavonols glycosides ; self-inclusion ; phenolic contents ; grape seed ; integrated food research ; antioxidants ; dedicated databases ; phenolic compounds ; non-extractable compounds ; value-added by-products ; phenolic acids ; dietary supplements ; berries jam ; phenolics ; inclusion complex ; sour cherry ; Pleurotus ostreatus ; catechins ; proanthocyanidins ; Chinese mistletoes ; nuclear magnetic spectroscopy ; nitric oxide scavengers ; quercitrin ; endothelial cell ; polyphenolic compounds ; Italian popular recipes ; green extraction ; non-extractable polyphenols ; classic extraction ; study approach ; daidzein ; ?-cyclodextrin ; Camellia sinensis ; antioxidant properties ; digestive enzyme ; extractable ; bioactive compounds ; principal component analysis ; non-extractable ; oxidative stress ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 64
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-04
    Beschreibung: Hydrogen sulfide (H2S), which was previously considered to be toxic, is now regarded as a burgeoning endogenous gaseous transmitter. H2S plays a vital role in the mechanism of response/adaptation to adverse environmental conditions as well as crosstalk with other signaling molecules, including ROS, by affecting the corresponding gene expression and subsequent enzyme activities. Both H2S and ROS are potent signaling molecules that can provoke reversible and irreversible oxidative post-translational modifications on cysteine residues of proteins such as sulfenylation or persulfidation, affecting the redox status and function of the target proteins. The dynamic interplay between persulfidation and sulfenylation occurring on cysteine residues is of great importance in response to environmental changes.The present Special Issue of IJMS has the aim of providing the most current findings on the function of signaling molecules, including H2S and ROS, in higher plants, and it is open to different types of manuscripts, including original research papers, perspectives, or reviews where either ROS, H2S, or related molecules could be involved at the biochemical or physiological levels.
    Schlagwort(e): antioxidant defense systems ; Cd stress ; hydrogen sulfide ; melatonin ; oxidative stress ; transportation and sequestration ; nitric oxide ; abscisic acid ; Ca2+ ; hydrogen peroxide ; abiotic stresses ; signal transmitters ; stomatal movement ; persulfidation ; drought stress ; nitrate reductase ; l-cysteine desulfhydrase ; chilling stress ; indole-3-acetic acid ; signaling pathway ; calcium deficiency ; endogenous H2S ; reactive oxygen species ; ERF2-bHLH2-CML5 module ; postharvest storage quality ; tomato ; cysteine desulfhydrase ; leaf senescence ; ARF ; auxin ; cold stress ; cucumber ; DREB ; module ; resistance ; root growth ; heavy metal ; salt ; DES1 ; ABI4 ; protein stability ; Brassica rapa ; mercury ; selenium ; biotic stress ; abiotic stress ; salicylic acid ; jasmonic acid ; ethylene ; phytohormones ; Arabidopsis ; manganese stress ; L-cysteine desulfhydrase ; antioxidant enzyme ; Allium ; garlic ; gas detector ; ion-selective microelectrode ; isozymes ; RBOHs ; signaling networks ; n/a ; thema EDItEUR::P Mathematics and Science ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
    Sprache: Englisch
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  • 65
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: After successful government-led afforestation projects, what are the challenges for forest management in the face of climate change in East Asia? This reprint presents studies from the natural and social sciences related to forest conservation, engineering, disaster sociology, and forest policy in China and Japan. The papers cover a range of topics, including forest owners' attitudes, forest resource utilization, evaluation of forestry mechanization and forest roads, characteristics of damage from torrential rains, resilience of rural communities, economic transformation, and others.
    Schlagwort(e): Yangtze River Delta ; forest resources abundance ; economic development ; ESG ; sustainable management ; corporate social responsibility (CSR) ; non-financial disclosure ; emerging market ; key state-owned forest area ; system coupling ; ecological construction ; economic transformation ; grey relational analysis (GRA) ; extreme value analysis ; daily rainfall ; floods ; rainfall-induced landslides ; regional frequency analysis ; station-year method ; Kyushu region ; CO2 emission ; forestry ; Gifu Prefecture ; input–output analysis ; renewable energy ; ripple effect ; eco-efficiency ; sustainable development ; forestry resources ; New Scheme of Forest Management ; Forest Management Law ; private forest ; small-scale forestry ; typology of forest owners ; Japan ; bearing capacity ; road construction method ; roadbed strength ; soil ; spur road ; forest road failure ; streamside ; stream crossing ; zero-order basin ; relative risk ; seisan shinrin kumiai ; ninka chien dantai ; common property resource ; developed countries ; external policy influence ; forest management activities ; local landscape ; observation ; depopulation ; municipal government ; local identity ; revitalization ; outsiders ; collaboration ; resilience ; small-scale forest road ; UAV ; Structure from Motion (SfM) ; earthwork volume ; under tree canopy ; productivity ; harvesting system ; processor tower yarder ; combined machine productivity ; combined labor productivity ; afforestation ; under-utilization ; forestry operation ; clearcutting ; economic losses ; societal losses ; rural community ; disaster-resilient forestry ; East Asia ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
    Sprache: Englisch
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  • 66
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The book ""Quality and Production of Forage"" is intended to keep readers updatedon the developments occurring in this field. As it is apparent that livestockanimals are important throughout the world because of the meat, milk and eggthey produce, knowledge about the forages available to animals must also beconsidered for increased production, quality and efficiency. This book providesinformation that readers will find considerably invaluable about forage feeds, suchas grass, legumes, and straw. The book is composed of ten papers, focusing on awide range of research activities and topics that feature the following concepts offorage: the effect of conservation method on forage protein value; Microbial thecomposition and mycotoxin content in forage; genetic diversity of forages; timelysowing to maximize yield for both grain and biomass; ensiling treatments onforage quality; the qualitative characteristics of different accessions of new foragespecies; forage policy influencing feed costs; feeding forage on animal health;high-protein tropical forages as alternative sources for poultry; impact of foragesin poultry diet and significance of forages in sustainable poultry productionsystems. This book will be an invaluable reference for students and professionalsin agricultural science and grassland and animal husbandry researches.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; S1-972 ; annual clover ; corn ; plant height ; forage production ; feed costs ; wilting ; population density ; Moringa oleifera ; alfalfa ; livestock ; digestibility ; hay ; sowing date ; biomass production ; clover ; tropical forages ; sustainability ; alternative protein ; plant ; animal ; dry matter ; genetic diversity ; chicken ; zearalenone ; production system ; forage ; energy balance ; grain yield ; nutritional composition ; deoxynivalenol ; grass ; silage ; policy ; path analysis ; poultry ; in vitro organic matter digestibility ; nitrogen ; nitrogen balance ; beneficial use ; lucerne ; forage yield ; anti-nutritional factors ; N fixation ; fungi ; planting ; markers ; crude protein ; epiphytic microflora ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 67
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Iron is an essential element for almost all organisms, a cofactor playing a crucial role in a number of vital functions, including oxygen transport, DNA synthesis, and respiration. However, its ability to exchange electrons renders excess iron potentially toxic, since it is capable of catalyzing the formation of highly poisonous free radicals. As a consequence, iron homeostasis is tightly controlled by sophisticated mechanisms that have been partially elucidated. Because of its biological importance, numerous disorders have been recently linked to the deregulation of iron homeostasis, which include not only the typical disorders of iron overload and deficiency but also cancer and neurodegenerative diseases. This leads iron metabolism to become an interesting therapeutic target for novel pharmacological treatments against these diseases. Several therapies are currently under development for hematological disorders, while other are being considered for different pathologies. The therapeutic targeting under study includes the hepcidin/ferroportin axis for the regulation of systemic iron homeostasis, complex cytosolic machineries for the regulation of the intracellular iron status and its association with oxidative damage, and reagents exploiting proteins of iron metabolism such as ferritin and transferrin receptor. A promising potential target is a recently described form of programmed cell death named ferroptosis, in which the role of iron is essential but not completely clarified. This Special Issue has the aim to summarize the state-of-the-art, and the latest findings published in the iron field, as well as to elucidate future directions.
    Schlagwort(e): QH301-705.5 ; QD415-436 ; Q1-390 ; developmental ; Anemia of chronic disease ; neurodegeneration ; supplementation ; MHC ; iron chelation therapy ; osteoblast ; serum biomarker ; FeSO4 ; haptoglobin ; prevention ; brain development ; pituitary ; trauma ; hepcidin ; Alzheimer’s disease ; chaotropes ; social behavior ; Africa ; macrophage ; anemia of inflammation ; Tfr2 ; chelation ; cardiomyocyte ; IV iron therapy ; Oxidative stress ; treatment ; chronic kidney disease ; iron homeostasis ; oxygen sensing ; iron chelators ; age-related macular degeneration (AMD) ; pharmaceutical targets ; non-transferrin-bound iron (NTBI) ; iron dextran ; pulmonary arterial hypertension ; labile iron ; low and middle income countries ; ferroportin ; gut microbiota ; reducibility ; non-HFE ; oxidative stress ; antitumor compound ; senescence ; electron transfer ; nanotechnology ; iron deficiency ; neonatal period ; heme oxygenase ; hypoxia ; Anemia ; NCOA4 ; patient blood management ; microbiome ; anemia ; iron mobilization ; iron release ; phlebotomy ; peritoneal dialysis ; Friedreich Ataxia ; ferritin ; CD8+ T cells ; M cells ; neurodegenerative disease ; NaFeEDTA ; vascular calcification ; cinnamic acid derivatives ; oral iron salts ; lipid ; acute lung injury ; Iron-sulfur ; Interleukin-6 ; neurodegeneration with brain iron accumulation ; macrophages ; erythroblastic islands ; cystic fibrosis ; neuroimmune responses ; flavin nucleotide ; hemopexin ; Iron chelators ; nutrient iron ; developing countries ; hereditary hypoferritinemia ; iron ; cancer ; Indonesia ; n/a ; Hfe ; HFE ; chronic heart failure ; iron supplementation ; intestinal inflammation ; TNF ; chelators ; hemolysis ; children ; pulmonary arterial smooth muscle cells ; cytokines ; didox ; intravenous iron ; T lymphocytes ; colorectal cancer ; infants ; liver ; ferritinophagy ; hereditary hyperferritinemia ; SCFA ; rheumatoid arthritis ; membrane interactions ; Sucrosomial® iron ; lung ; Kupffer cell ; iron chelation ; erythrophagocytosis ; acute kidney injury ; neurophysiology ; iron transporters ; iron absorption ; infection ; ferroptosis ; fluorescent iron chelator ; neonatal ; SNC ; immunity ; mycobacteria ; non-haem iron ; natural history ; 3-hydroxy-4-pyridinone ; haem ; inflammation ; bone homeostasis ; cardiovascular disease ; heme ; heme homeostasis ; protein binding ; brain ; iron deficiency anemia ; Fe2+-chelating activity ; bioengineering ; Mek/Erk ; Bmp/Smad ; iron delivery ; genetic hemochromatosis ; osteoclast ; histidine ; rhodamine ; COPD ; hemorrhage ; antibacterial activity ; bacteria ; SLC40A1 ; transferrin receptor ; drug delivery ; nanocage ; soybean seed ferritin ; pig ; iron metabolism ; kidney ; innate immunity ; cataracts syndrome ; erythropoiesis ; obesity ; mucosal immunity ; iron overload ; fluorophore ; binding ability ; inflammatory bowel disease (IBD) ; osteoporosis ; biomarker ; bioavailability ; adverse event profile ; metabolism ; iron-carbohydrate complex ; kinetics ; flavonoids ; iron regulatory proteins ; lung infection ; non transferrin bound iron ; central nurse macrophage ; iron processing ; malaria ; neurodegenerative diseases ; multifunctional iron chelators ; retina ; neuroinflammation ; anti-hepcidin therapy ; lung diseases ; anaemia ; RRM2 ; cognition ; mitochondria ; therapy ; NBIA ; red pulp macrophage ; efficacy ; hemochromatosis ; tolerability ; oral iron therapy ; growth ; venesections ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 68
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Consumer interest in plant-based diets has been rapidly increasing in the past decade. Non-dairy and non-meat alternatives have gone mainstream. New products are appearing in the marketplace continually. The marketplace has been driven recently by millennials and flexitarians. Food companies have focused on providing nutritious food products that satisfy the demand for alternative items that look and taste like their animal counterparts. The marketplace wants products that improve human and planetary health worldwide. Questions have arisen as to how nutritionally sound and healthy are these products. How sustainable are these plant-based diets? How significantly do they alter traditional dietary patterns? What impact do they have on food security? Do these plant-based meat and dairy alternatives help lessen environmental degradation? Are the new products considered ultra-processed foods? What are the barriers and motivations that drive people to switch to a plant-based diet? Will plant-based diets help in the goal to greatly diminish malnutrition and over-nutrition (leading to obesity) around the world? These questions challenge scientists to provide meaningful answers through their ongoing research. Some of these issues are discussed in this reprint, based upon the latest research.
    Schlagwort(e): planetary health ; Paris agreement ; linear programming ; nutrition ; greenhouse gas emission ; alternative diets ; sustainability ; flexitarian ; vegetarian ; vegan ; plant-based meat alternatives ; nutrient intakes ; dairy alternative ; dairy substitute ; cheese analogues ; vegan cheese ; vegetarian cheese ; plant-based alternatives ; pregnancy ; nutritional requirements ; food production system ; environment ; diet ; meat replacement ; non-meat protein source ; environmental sustainability ; consumer preference ; food choice ; non-dairy yogurt alternatives ; plant-based yogurts ; nutrient composition ; fortification ; calcium ; vitamin D ; vitamin B12 ; protein ; sugar ; plant-based diets ; microbiome ; CV disease ; diabetes ; bone health ; life cycle ; pea proteins ; plant proteins ; sarcopenia ; skeletal muscle ; protein digestibility ; muscle protein metabolism ; chronic kidney disease ; implementation ; barriers ; enablers ; cross-sectional survey ; qualitative research ; food waste ; global warming ; vegetarian meals ; hospital setting ; plant based ; public health ; pregnancy complications ; preterm delivery ; small for gestational age ; preeclampsia ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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  • 69
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: This book is generally focused on food choice and which factors are associated with the decisions that define people’s eating behaviour. These factor are highly variable and include influences from the surrounding environment as well as the individual characteristics of each person. The book includes a number of chapters that address these issues from different points of view. Some explore the psychology of food choices or the cultural aspects and tradition, as well as the influence of surrounding contexts. Others focus on the role of lifestyle on eating practices and health motivations, but also the food marketing and the sensory aspects of food, as a way to incentive consumption. Finally, sustainability concerns and environmental impacts can also shape and help change people’s food choices.Within the chapters gathered on this book you will find key topics that apply to everyday food choices or that can help target food consumption goals towards better health, more sustainable food chains and happier life styles.
    Schlagwort(e): eating determinants ; healthy diet ; emotions ; feeding behavior ; socio-cultural environment ; instrument validation ; edible flowers ; food security ; gourmet kitchen ; knowledge ; questionnaire survey ; supercritical CO2-drying ; beetroot snacks ; preference mapping ; mean drop analysis ; perceptions ; healthy eating ; emotional motivations ; individual differences ; perceived risk ; functional risk ; psychological risk ; social risk ; physical risk ; negative past experiences ; structural equation modeling ; consumer behavior ; buying intention ; consumer acceptance ; marketing innovation ; price ; beverages ; milk permeate ; wheat bran ; fruit/berry by-products ; antimicrobial properties ; antioxidant properties ; overall acceptability ; emotions induced for consumers ; literature survey ; Scopus ; brands ; consumer preferences ; milk ; cheese ; butter ; yogurt ; authenticity scale ; genuine ; cheese specialty ; country-of-origin labels ; product identification ; stated willingness to consume ; food choices ; health ; motivation ; BMI ; food behavior ; education ; food choice ; food consumption ; university ; workplace ; determinants ; barriers ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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    Publikationsdatum: 2024-04-05
    Beschreibung: Targeted therapy has developed significantly in the last one and half decades, prescribing specific medications for treatment of particular diseases, such as cancer, diabetes, and heart disease. One of the most exciting recent developments in targeted therapies was the isolation of disease-specific molecules from natural resources, such as animal venoms and plant metabolites/toxins, for use as templates for new drug motif designs. In addition, the study of venom proteins/peptides and toxins naturally targeted mammalian receptors and demonstrated high specificity and selectivity towards defined ion channels of cell membranes. Research has also focsed intensely on receptors. The focus of this Special Issue of Toxins addressed the most recent advances using animal venoms, such as frog secretions, bee/ant venoms and plant/fungi toxins, as medicinal therapy. Recent advances in venom/toxin/immunotoxins for targeted cancer therapy and immunotherapy, along with using novel disease-specific venom-based protein/peptide/toxin and currently available FDA-approved drugs for combinationtreatments will be discussed. Finally, we included an overview of select promising toad/snake venom-based peptides/toxins potentially able to address the forthcoming challenges in this field. Both research and review articles proposing novelties or overviews, respectively, were published in this Special Issue after rigorous evaluation and revision by expert peer reviewers.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; cane toad ; n/a ; B cell non-Hodgkin lymphoma ; Malaysian cobras ; complement system ; decay accelerating factor ; neuroblastoma ; atopic dermatitis ; complement dependent cytotoxicity ; antioxidant enzymes ; bacterial adhesion ; cancer therapy ; N. kaouthia ; anuran skin secretion ; frog ; Apis mellifera syriaca ; solid phase extraction ; bee venom phospholipase A2 (bvPLA2) ; disintegrin ; toad toxins ; immunotoxins ; ribosome-inactivating proteins ; antimicrobial peptide (AMP) ; drug design ; Moxetumomab pasudotox ; snake venom ; antiviral activity ; in vitro effects ; bombesin-related peptide ; oxidative stress biomarkers ; half-life ; blood vessel formation ; target therapy ; 2 ; MYCN ; indolealkylamines ; Huachansu ; membrane attack complex ; bouganin ; bee venom ; SEM ; anticancer activity ; antimicrobial peptide ; house dust mite extract (DFE) ; mannose receptor ; O. hannah ; bicarinalin ; gastric cells ; melittin ; LC-ESI-MS ; dermaseptin ; smooth muscle ; apoptosis ; anticancer ; N. sumatrana ; Helicobacter pylori ; inflammation ; immunotherapy ; atopic dermatitis (AD) ; immunotoxin ; mantle cell lymphoma ; clearance ; mass spectrometry ; Bougainvillea ; rRNA N-glycosylase activity ; fungal toxin ; skin inflammation ; targeted therapy ; 4-dinitrochlorobenzene (DNCB) ; Bee venom ; VEGF ; Chansu ; bufadienolides ; obsessive–compulsive disorder (OCD) ; BLF1 ; antimicrobial activity ; orellanine ; VB6-845 ; acute lymphoblastic leukemia ; ribosome-inactivating protein ; CD206 ; molecular cloning ; cancer ; CD22 ; eIF4A ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 71
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: This textbook is dedicated to the study of genetic factors contributing to autism and includes a collection of original research and review articles related to this topic. Autism spectrum disorders (ASD) include a collection of neurodevelopmental disorders characterized by three recognized behavioral domains involving difficulties in communication, social interaction and repetitive behavior. ASD affects 1 to 2 percent of children and is on the increase worldwide. Significant genetic contributions and mechanisms underlie the causation of ASD. Advances in genetic technology and better awareness have led to a diagnosis of 50 to 70 percent of individuals with ASD primarily due to chromosomal abnormalities, submicroscopic deletions or duplications now identified with high-resolution microarray analysis, next-generation DNA (exome) sequencing of gene variants or mutations, recognized single gene disorders or metabolic disturbances. Through discovery by searching genomic databases and peer-reviewed research articles, nearly 800 genes have been identified to contribute to ASD. Highlights in the field of autism research, discovery and identification of genetic components with characterization will be addressed. Furthermore, reviews of current understanding of the causes and diagnostic approaches for ASD and related syndromes will be presented along with discussion of psychiatric/behavior comorbidities and related features, environmental risk factors, parental attitudes and treatment.
    Schlagwort(e): QH301-705.5 ; genetic ; treatment ; genes ; biomarkers ; copy number variants and mutations ; genetic factors ; next generation DNA exome sequencing and functional analysis ; autism and autism spectrum disorders ; causation and etiology ; reviews ; neurodevelopment and physiology testing ; syndromes ; environmental risk factors ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 72
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    Publikationsdatum: 2024-04-05
    Beschreibung: The Special Issue to provide a forum for contemporary studies of the genetics, genomics and phenomics of productivity traits in forage and bioenergy grasses, along with the application of such data to breeding practices and cultivar development.
    Schlagwort(e): QH301-705.5 ; forage grass ; biomass ; protein content ; lignocellulosic content ; persistence ; seasonal yield ; soluble carbohydrates ; bioenergy grass ; herbage digestibility ; biofermentation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 73
    Publikationsdatum: 2024-04-05
    Beschreibung: Intensive agriculture has generally resulted in higher productivity, but also in a trend towards decreasing levels of agro-biodiversity, which represents a key point in ensuring the adaptability and resilience of agro-ecosystems in the global challenge to produce more and better food in a sustainable way. The biodiversity of vegetable crops includes genetic diversity—both as species diversity (interspecific diversity) and as a diversity of genes within a species (intraspecific diversity) with regard to the vegetable varieties grown—and the diversity of agro-ecosystems (agro-biodiversity). The purpose of this Special Issue is to publish high-quality research papers addressing recent progress and perspectives on different aspects related to the biodiversity of vegetable crops. Original, high-quality contributions that have not yet been published, or that are not currently under review by other journals have been sought. The papers in this Special Issue cover a broad range of aspects and report recent research results regarding agro-biodiversity, which continues to be of significant relevance for both genetic and agricultural applications. All contributions are of significant relevance and could stimulate further research in this area.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; S1-972 ; polyphenols ; landraces ; artichoke ; wild edible plants ; microsatellite marker ; mountain agriculture ; HPLC analyses ; Posidonia oceanica (L.) Delile ; apulian landraces ; traditional crops ; genetic reserve ; landrace ; meristem-tip culture ; databases ; long storage time ; Tanzania ; cultivated vegetables ; crop wild relative ; history ; safeguarding ; nutrition ; conservation ; Crithmum maritimum L. ; Italy ; crop population ; Tiggiano carrot ; germplasm ; local varieties ; in situ conservation ; homegardens ; thermotherapy ; genetic resources ; Solanum lycopersicum L. ; plant genetic resources ; recovery ; vegetables ; sanitation ; agriculture ; ecology ; domestication ; heavy metal ; ecotype ; cropping patterns ; virus-sanitation ; agrobiodiversity ; ecotypes ; Apium graveolens ; genetic distance ; genetic variability ; plant genetic resources populations ; food safety ; neglected and underutilized species ; heirloom ; geographical origin area ; seed bank ; climate change adaptation ; bioactive compounds ; genetic differentiation ; growing substrate ; characterization ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 74
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Biomass can be converted to energy, biofuels, and bioproducts via thermochemical conversion processes, such as combustion, pyrolysis, and gasification. Combustion technology is most widely applied on an industrial scale. However, biomass gasification and pyrolysis processes are still in the research and development stage. The major products from these processes are syngas, bio-oil, and char (called also biochar for agronomic application). Among these products, biomass chars have received increasing attention for different applications, such as gasification, co-combustion, catalysts or adsorbents precursors, soil amendment, carbon fuel cells, and supercapacitors. This Special Issue provides an overview of biomass char production methods (pyrolysis, hydrothermal carbonization, etc.), characterization techniques (e.g., scanning electronic microscopy, X-ray fluorescence, nitrogen adsorption, Raman spectroscopy, nuclear magnetic resonance spectroscopy, X-ray photoelectron spectroscopy, and temperature programmed desorption and mass spectrometry), their properties, and their suitable recovery processes.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; S1-972 ; n/a ; Boudouard reaction in gasification ; Chinese reed ; underground coal gasification ; food waste ; kinetic models ; fixed bed combustor ; reactor modelling ; AAEMs ; anaerobic digestion ; grape marc ; adsorption isotherms ; Texaco pilot plant ; biomass valorization ; food waste compost ; CH4 adsorption ; gaseous emissions ; polycyclic aromatic hydrocarbon (PAH) ; waste wood ; coconut shells ; kinetic model ; char oxidation ; low-rank coal char ; nutrients ; characteristic time analysis ; kinetic parameters ; ash from biomass ; combustion parameters ; biomass ; thermal characteristics ; biocrude ; reaction kinetics ; sludge cake ; gasification ; pellets ; characterization ; ash layer ; energy recovery efficiency ; internal diffusion resistance ; FT-IR ; giant miscanthus ; pyrolysis ; olive mill solid wastes (OMSWs) ; food-waste biochar ; melting phenomenon ; chemisorption ; steam gasification ; NaCl template ; biomass production ; textural characterization ; desalination ; ash fusion temperature (AFT) ; thermogravimetric analysis ; combustion ; chemical speciation ; sawdust ; NaCl ; effective diffusion coefficient ; kinetics ; breakthrough curves ; biochar engineering ; biochar ; amino acid ; high heating value (HHV) ; salty food waste ; ELECTRE III ; interferences ; multicriteria model ; pyrrole ; interactions ; biogas purification ; fertilisation ; NOx ; pyrolysis conditions ; steam ; partial combustion reaction in gasification ; CO2 adsorption ; poultry slaughterhouse ; hydrothermal carbonization (HTC) ; calorific value ; oxygen enrichment ; porosity ; nitrogen ; hydrothermal carbonization ; thermogravimetric analysis (TGA) ; MTDATA ; activated carbon ; active site ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 75
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Hardwood-dominated temperate forests (mostly in Eastern North America, Europe, North East Asia) provide valuable renewable timber and numerous ecosystem services. Many of these forests have been subjected to harvesting or conversion to agriculture, sometimes over centuries, that have greatly reduced their former extent and diversity. Natural regeneration following harvesting or during post-agricultural succession has often failed to restore these forests adequately. Past harvesting practices and the valuable timber of some species have led to a reduction in their abundance. The loss of apex predators has caused herbivore populations to increase and exert intense browsing pressure on hardwood regeneration, often preventing it. Particularly important are fruit, nut and acorn bearing species, because of their vital role in forest food webs and biodiversity. Restoring hardwood species to natural forests in which they were formerly more abundant will require a number of forest management actions (e.g., resistant hybrids, deer exclosures/protectors, enrichment planting, underplanting, etc.). Similarly, reforesting areas that were once natural forests will also require new silvicultural knowledge. Global warming trends will intensify the need for interventions to maintain the diversity and function of temperate hardwood forests, as well as for increase hardwood reforestation.
    Schlagwort(e): QH301-705.5 ; QH540-549.5 ; Q1-390 ; Fagaceae species ; soil disturbance ; non-timber forest products ; precision restoration ; protected landscape area ; tree selection ; cultural diversity ; Quercus rubra ; hardwood restoration ; enrichment planting ; sub-tropical hardwoods ; agroforestry ; herbicide effects ; biological diversity ; competition ; Juglans nigra L. ; understorey ; invasive plants ; wildfire ; forest restoration ; Quercus macrocarpa ; riparian forest restoration ; vegetation management ; assisted migration ; sugar maple ; deer browsing ; species composition ; tolerance ; phosphorus ; growth efficiency index ; floristic quality index ; shelterwood ; Carya cordiformis (Wangenh.) K. Koch ; monitoring ; indicators ; seed predation ; Bioclimatic niche ; non-parametric correlation ; unmanaged forest ; Native Americans ; abandoned agricultural field ; native mixed forests ; tree vigor ; forest diversity ; predation ; weed control ; nitrate ; facilitation ; inventory ; hardwoods ; Mexican tree species ; yellow birch ; tree plantation ; seedling establishment ; deer abundance ; avian guilds ; Pinus strobus L. ; Central Hardwood Forest region ; Pinus strobus ; Durango ; MaxEnt ; Juglans nigra ; oak regeneration ; forest regeneration ; Quercus rubra L. ; deer herbivory ; ecosystem services ; tree shelter ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 76
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: This Special Issue focuses on feeding and feed technology advances and challenges in aquaculture. These are of particular interest since aquaculture and fisheries are considered crucial sources of animal protein in human diets, providing around 17% of global edible animal protein. Special attention is given to alternative sources of fish meal and how substitutions can influence the metabolism, immune response, and disease resistance of the targeted species. Moreover, the impact of plant extracts on growth performances, physiological responses, immunity, and intestinal health is addressed.
    Schlagwort(e): Pacific bluefin tuna ; squid meal ; krill meal ; heat treatment ; growth performance ; dietary protein ; glycolipid metabolism ; immune response ; Streptococcus agalactiae ; high temperature ; Macleaya cordata extract ; serum lipid ; antioxidant ability ; intestinal microbiota ; intestinal health ; Anguilla rostrata ; feed additives ; immune gene expressions ; antioxidant defensive system ; Spirulina ; digestive enzymes ; hepatic enzymes ; gene expression ; aquaculture ; cyanobacteria ; Bangladesh ; children ; dry fish ; malnutrition ; minerals ; nutrients ; protein ; vitamins ; women ; whitebait ; larval diet ; formulated feed ; PUFA ; HUFA ; herbal medicines ; growth ; striped catfish ; immunity ; largemouth bass ; pompano ; amberjack ; red drum ; algal oil ; olive flounder ; fish meal replacement ; meat meal ; regression analysis ; innate immune response ; Lamiaceae ; fish ; health ; antioxidant ; nutrition ; Litopenaeus vannamei ; Yarrowia lipolytica ; Haematococcus pluvialis ; astaxanthin ; pigmentation deposit ; antioxidation ; Ctenopharyngodon idellus ; Phragmites australis ; serum biochemistry ; immune-related factors ; immune gene ; alternative protein source ; essential amino acid ; insect meal ; protein replacement ; T. tinca ; whole-body composition ; feed ; insects ; innovation ; sustainability ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAF Fisheries and related industries
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  • 77
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Currently, in the cosmetic industry, there is an increasing interest in natural extracts, particularly plant extracts. The inclusion of antioxidants in topical formulations may contribute to minimize skin oxidative stress, which has been associated with aging. Many herbal agents used in cosmetics have been selected by a process of ‘trial and error’ and, thus, are used on the basis of experience rather than of experimental investigation. Nevertheless, there is now a growing scientific evidence that plants possess a vast and complex arsenal of active ingredients able not only to calm or smooth but also to actively restore, heal, and protect the human skin. In addition, plant extracts may contain compounds with antimicrobial or other beneficial properties, influencing the formulation of natural and non-chemical cosmetic products. The public trend towards natural and sustainable products is ongoing. Although the term “plant extract” inherently purports their beneficial and benign properties, these products could have adverse reactions in individuals. Therefore, it is essential to ensure quality and safety of these extracts in cosmetic products before embarking on the more arduous task of ensuring efficacy.
    Schlagwort(e): QH301-705.5 ; Cosmetic ; In vivo ; Plant extract ; Antioxidant ; In vitro ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 78
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    Publikationsdatum: 2024-04-05
    Beschreibung: This book is a printed edition of the Special Issue Fertilizer Application on Crop Yield that was published in Agronomy
    Schlagwort(e): QH301-705.5 ; Q1-390 ; S1-972 ; organic N ; ammonia ; NPK amendments ; corn–soybean rotation ; soil acidity ; phosphorous ; maize yield response to K ; biofertilizer ; agroforestry system ; Copper ; organic farming ; soil nitrogen pools ; net returns ; mineral N ; grain quality ; fertilizer management ; nutrient expert for maize ; sustainability ; organic nutrients ; conservation agriculture ; agronomic response ; S fertilization ; global food demand ; Zea mays L. ; N fertilizer ; nitrogen recovery efficiency ; Bacillus pumilus ; Orychophragmus violaceus L. ; soil erosion ; soil health ; saline tract ; soil K supply ; soil N mineralization ; soil biota ; potassium ; production system ; nitrate reductase activity ; site-specific K management ; Value Cost Ratio ; durum wheat ; conventional farming ; nitrate ; soil organic matter ; grain yield ; integrated nutrient management ; K use efficiency ; rice-wheat system ; forage legume ; nitrogen physiological recovery ; NADH ; chemical fertilizers ; evergreen agriculture ; green manure ; N fertilization ; yield ; NADH-dehydrogenase ; wheat ; site-specific nutrient management ; hybrid rice ; NUE ; balanced use of fertilizers ; growth promotion ; calcium ; humid Mediterranean climate ; Complex I ; rice ; maize ; Zinc ; potentially mineralizable N ; Agrotain® urea ; economics ; nitrate assimilation ; management ; nitrogen uptake ; wheat yields ; nitrogen use efficiency (NUE) ; soil N supply ; maize crop manager ; long-term productivity ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 79
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    Publikationsdatum: 2024-04-05
    Beschreibung: The sensory properties of foods are the most important reason people eat the foods they eat. What those properties are and how we best measure those properties are critical to understanding food and eating behavior. Appearance, flavor, texture, and even the sounds of food can impart a desire to eat or cause us to dismiss the food as unappetizing, stale, or even inappropriate from a cultural standpoint. This Special Issue focuses on how sensory properties are measured, the specific sensory properties of various foods, and consumer behavior related to which properties might be most important in certain situations and how consumers use sensory attributes to make decisions about what they will eat. This Special Issue contains both research papers and review articles.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; mayonnaise ; Choquet integral ; multi-attribute time-intensity (MATI) data ; foods ; fuzzy measure ; specialty food ; monosodium glutamate (MSG) ; food label ; plant breeding ; consumer test ; perception ; multi-criteria decision-making ; interaction indices ; multicollinearity ; unique food products ; sensory thresholds ; natural ; quality control ; Shapley value ; processing ; thermosensing ; willingness to pay ; esophageal cancer ; cross-cultural affective test ; carryover effects ; Prunus dulcis ; hot beverages ; sensory acceptability ; mixed models ; chicken soup ; sensory bias ; product development ; temperature ; methodological study ; relative importance of attributes to liking ; product improvement ; nonlinear models ; consumer ; lexicon ; descriptive sensory analysis ; emulsification ; ingredient ; hydroSOStainable products ; temporal drivers of liking (TDOL) ; texture ; MSG substitutes ; functional data analysis ; food ; ethnic food ; descriptive analysis ; LMG statistic ; shelf life ; sensory evaluation ; sensory ; coffee ; fruit chews ; descriptive ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 80
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    Publikationsdatum: 2024-04-05
    Beschreibung: Food fermentation is one of the most ancient processes of food production that has historically been used to extend food shelf life and to enhance its organoleptic properties. However, several studies have demonstrated that fermentation is also able to increase the nutritional value and/or digestibility of food. Firstly, microorganisms are able to produce huge amounts of secondary metabolites with excellent health benefits and preservative properties (i.e., antimicrobial activity). Secondarily, fermented foods contain living organisms that contribute to the modulation of the host physiological balance, which constitutes an opportunity to enrich the diet with new bioactive molecules. Indeed, some microorganisms can increase the levels of numerous bioactive compounds (e.g., vitamins, antioxidant compounds, peptides, etc.). Moreover, recent advances in fermentation have focused on food by-products; in fact, they are a source of potentially bioactive compounds that, after fermentation, could be used as ingredients for nutraceuticals and functional food formulations. Because of that, understanding the benefits of food fermentation is a growing field of research in nutrition and food science. This book aims to present the current knowledge and research trends concerning the use of fermentation technologies as sustainable and GRAS processes for food and nutraceutical production.
    Schlagwort(e): QH301-705.5 ; QR1-502 ; Q1-390 ; chemical refining ; Lactic acid bacteria ; grapevine ; sourdough ; vegetable oil ; platelet-activating factor ; biogenic amines ; aglycones ; food fermentation ; food by-products ; beer ; Blakeslea trispora ; ?-aminobutyric acid (GABA) ; fish oil ; ?-glucosidase ; Thunnus thynnus ; lycopene ; histidine decarboxylase (hdc) gene ; fermentation ; wine ; ?-aminobutyric acid GABA ; thrombin ; isoflavones ; polar lipids ; phenolic compounds ; lactobacilli ; fatty acid profile ; antithrombotic ; UHPLC/ESI-QTRAP ; orange powder ; tyrosine decarboxylase (tdc) gene ; Sparus aurata ; amaranth flour ; soybean extract ; Penicillium citrinum ; indoleamines ; cardiovascular disease ; brewer’s spent grain ; Pecorino di Farindola ; liquid chromatography ; by-products ; lactic acid bacteria ; grains ; bioactive peptides ; Dicentrarhus labrax ; fungi ; raw milk ewe’s cheese ; ?-aminobutyric acid ; bioactive compounds ; hops ; volatile components ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 81
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Over the past decades, researchers have gathered data demonstrating that vitamin D and its metabolites possess activities far beyond the classic regulation of calcium–phosphate homeostasis. It is now well established that vitamin D is essential for the proper functioning of the musculoskeletal, cardiovascular, nervous, and immune systems. Furthermore, vitamin D and its analogs were shown to regulate proliferation and differentiation of keratinocyte, immune cells, and numerous cancer-derived cells, both in vivo and in vitro. On the other hand, population base studies have provided evidence that global vitamin D deficiency is correlated with the occurrence and aggravation of symptoms of skeletal, cardiovascular autoimmune, and skin disease; infections; metabolic and cognitive disorders; multiple types of cancers; as well as overall mortality. This Special Issue of International Journal of Molecular Sciences, entitled “Vitamin D and Human Health”, summarizes recent advances in our understanding of pleiotropic activity of vitamin D with a focus on its protective role against cancer, hypertension, viral infections, and neurological diseases, as well as its impact on the immune system and mitochondria. Furthermore, eight research papers provide new insight into vitamin D research and highlight new directions and targets in the prevention and treatment of human diseases.
    Schlagwort(e): QH301-705.5 ; Vitamin D ; supplementation ; extra-skeletal effects ; analogs of vitamin D ; therapy and prevention ; vitamin D deficiency ; vitamin D activity and metabolism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 82
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Wearable electronics and embedded computing systems have been receiving a great deal of interest over the last two decades in research and commercial fields, with a special focus on biomedical applications. The key benefits introduced by these systems include their small size, lightweight, low-power consumption, and, of course, wearability. Major human-centered applications are related to medicine, enabling outpatient care and enhancing the quality of life for chronic disease patients, maybe preventing unnecessary hospitalization. These technological devices can indeed be cost effective and provide doctors with more accurate and reliable data. Exemplary engineering input has focused on developing innovative sensing platforms, adaptable to different environments and user needs, smart textile technology, miniaturized electronics and sensors, energy harvesting, wireless body area networks, and so on. This has provided the possibility of gathering information on several activities, such as during daily activities or sleep, during specific tasks, at home, in the lab, and in the clinic, in the form of physiological signals. This book includes cutting-edge research articles, as well as reviews describing and assessing wearable devices, or proposing novel wearable sensors, computational efficient algorithms for physiological signal processing through embedded computing, collection of environmental/behavioral/psychological data, data fusion, detection and quantification of symptoms, decision support for medical doctors, and communication between patient and doctor.
    Schlagwort(e): QH301-705.5 ; RC31-1245 ; QA1-939 ; electronics ; human-computer interaction ; haptics ; signal processing ; Wearable systems ; monitoring ; biomedical sensors ; biomedical signal ; physiological data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 83
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Dual specificity phosphatases (DUSPs) constitute a heterogeneous group of protein tyrosine phosphatases with the ability to dephosphorylate Ser/Thr and Tyr residues from proteins, as well as from other non-proteinaceous substrates including signaling lipids. DUSPs include, among others, MAP kinase (MAPK) phosphatases (MKPs) and small-size atypical DUSPs. MKPs are enzymes specialized in regulating the activity and subcellular location of MAPKs, whereas the function of small-size atypical DUSPs seems to be more diverse. DUSPs have emerged as key players in the regulation of cell growth, differentiation, stress response, and apoptosis. DUSPs regulate essential physiological processes, including immunity, neurobiology and metabolic homeostasis, and have been implicated in tumorigenesis, pathological inflammation and metabolic disorders. Accordingly, alterations in the expression or function of MKPs and small-size atypical DUSPs have consequences essential to human disease, making these enzymes potential biological markers and therapeutic targets. This Special Issue covers recent advances in the molecular mechanisms and biological functions of MKPs and small-size atypical DUSPs, and their relevance in human disease.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; hematopoietic cells ; DEPArray ; n/a ; neuroblastoma ; liver steatosis ; MAPK phosphatase ; DUSP-4 ; granule neurons ; neuronal differentiation ; DUSP10 ; cytokines ; MAPKs ; single cell analysis ; macrophage ; asthma ; E. coli infection ; MAPK ; Cpp1 ; nucleotide receptors ; atypical DUSP ; RSV ; Pmp1 ; cannabinoids ; astrocytes ; sepsis ; influenza ; signaling ; triple-negative breast cancer (TNBC) ; differentiation ; HDAC6 (histone deacetylase isoform 6) ; atypical dual-specificity phosphatases ; microtubules ; respiratory viruses ; MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) ; dual-specificity phosphatase ; Msg5 ; TLR signaling ; mitogen-activated protein kinase ; fungal MKPs ; macrophages ; MAP Kinase Phosphatase-2 ; inflammation ; Sdp1 ; circulating tumor cells (CTCs) ; MAP kinases ; MAP kinase phosphatases ; P2X7 ; proliferation ; BDNF ; P2Y13 ; T cell ; hypertriglyceridemia ; integrated omics analysis ; post-translational modification ; rhinovirus ; protein stability ; ubiquitination ; dual-specificity phosphatases ; Mkp-1 ; cancer ; brain metastasis ; HER2 ; COPD ; pseudophosphatase ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 84
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Mangrove forests are in constant flux due to both natural and anthropogenic forces. The changing mangroves will have significant consequences to coastal communities. Observation and monitoring of the distribution and dynamics of mangroves is central to a wide range of scientific investigations conducted in both terrestrial and marine ecosystems. Recent advancements in remote sensing data availability, image-processing methodologies, computing and information technology, and human resource development have provided an opportunity to observe and monitor mangroves from local to global scales on a regular basis. The spectral, spatial, and temporal resolution of remote sensing data and their availability have improved, making it possible to observe and monitor mangroves with unprecedented spatial thematic and temporal details. This journal Remote Sensing Special Issue reprint dedicated to the observation and monitoring of mangroves using remote sensing from local to global scales. The Issue broadly covers the application of remote sensing using optical (multi-spectral and hyperspectral), radar, and Lidar data obtained from multiple platforms including ground, air, and space. The research papers published use the latest techniques to acquire, manage, exploit, process, and analyze a wide variety of remote sensing data for mangrove forest applications. Both research papers and innovative review papers are included.
    Schlagwort(e): mangrove ; natural recovery ; artificial neural network ; Sentinel-2 ; transfer learning ; change detection ; coastal region ; remote sensing ; fragmentation ; productivity ; land cover change ; mangrove ecosystem ; random forest (RF) ; Google Earth Engine (GEE) ; Sentinel ; synthetic aperture radar (SAR) ; optical ; aerial roots ; global sensitivity analysis ; PAWN ; canopy reflectance model ; vegetation index (VI) ; mangroves ; Landsat ; mangrove forests ; time series ; Google Earth Engine ; random forests ; phenology ; TIMESAT ; climate ; monitoring ; Great Barrier Reef ; Hainan Island ; CLUE-S ; spatio-temporal simulation ; future change trends ; mangrove species ; spectrometer ; spectral reflectance ; WorldView-2 ; dendrogram ; extent ; mapping ; sentinel-2 ; global mangrove watch ; remote sensing-based monitoring ; plantation ; restoration ; dieback ; Bay of Bengal ; Red River Delta ; Vietnam ; vegetation index ; mangrove index ; mangrove forest ; mangrove above ground ; biomass ; carbon sink ; bibliometric analysis ; Sembilang National Park (Indonesia) ; machine learning ; satellites images ; geoprocessing ; rehabilitation program of mangroves ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
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  • 85
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Antioxidants in food have a dual role; on the one hand, they preserve the quality and shelf life of food products; on the other hand, they function as an external aid, helping to defend our living cells from the threat of oxidative stress. Therefore, foods rich in antioxidants are a useful tool to reduce morbidity and prevent degenerative diseases. Consequently, research related to antioxidants is continually growing. This book brings together 21 articles regarding the latest advances in the most relevant fields of food antioxidant research; from the identification and characterization of new active components, to their molecular mechanisms and the scientific evidence of their clinical use and effectiveness.
    Schlagwort(e): green tea extract ; food processing ; tannase ; ultrasound ; antioxidant activity ; liver injury ; acclimatisation ; antioxidant defences ; chlorophyll fluorescence ; in vitro culture ; peroxidase ; stevia plants ; 7S basic globulins ; anti-inflammatory protein ; antioxidant protein ; cytokines ; glutathione ; iNOS ; nitric oxide ; oxidative stress ; sweet lupins group ; home-cooking ; extra virgin olive oil ; UPLC-ESI-QqQ-MS/MS ; healthy cooking ; Mediterranean diet ; phenolic compounds ; bioactive compounds ; functional pasta ; gluten-free pasta ; bioaccessibility ; bioavailability ; whole grain ; composite flour ; legumes ; food by-products ; avocados (Persea americana Mill.) ; low temperatures ; plastochromanol-8 ; tocotrienols ; tocopherols ; tocochromanols ; kombucha ; tea ; fermentation ; antioxidant ; flavonoids ; polyphenols ; ascorbic acid ; chlorophyll and carotenoid content ; biodiversity ; Capsicum annuum L. ; β-carotene ; statistical analysis ; rye bread ; microencapsulation ; phenolics ; in vitro relative bioaccessibility ; lipoxygenase ; cyclooxygenase ; acetylcholinesterase ; biological activity ; lycopene ; antioxidants ; cancer ; diabetes ; cardiovascular diseases ; skin disorders ; free radicals ; spectrophotometer ; limitations ; chemical reactions ; colorimetry ; anthraquinone ; free radical scavenging ; inflammatory cytokines ; apoptosis ; Rumex crispus ; skins ; seeds ; Vitis vinifera ; cyclic voltammetry ; anthocyanin metabolites ; cardioprotection ; hepatoprotection ; nephroprotection ; neuroprotection ; antioxidant peptides ; element of pork carcasses ; spectrometric analysis ; ascorbate ; ascorbate–glutathione cycle ; capsaicin ; catalase ; dihydrocapsaicin ; NADP-dehydrogenases ; superoxide dismutase ; red cabbage ; in vitro gastrointestinal digestion ; acid-resistant capsule ; UHPLC-Q-Orbitrap HRMS ; apples ; reducing and chelating capacity ; HPLC–DAD–MS/MS ; Dillenia indica ; heme oxygenase 1 (HO-1) ; nuclear factor erythroid 2-related factor 2 (Nrf2) ; RAW 264.7 cells ; apo-carotenals ; bone ; osteoclasts ; NFκB ; synergy ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
    Sprache: Englisch
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  • 86
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Precision Medicine, understood as “the emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person” is currently one of the most talked about themes in biomedicine and great efforts are being made internationally to turn this concept into a reality. As the concept of Precision Medicine spreads, so too does that of “Precision Nutrition”, which would have to take individual variability into account when recommending personalized diets. Although huge progress has been made over recent years in research into the genotype in inter-individual responses to diet, proving that this heterogeneity does indeed exist, we still do not have top level scientific evidence to make the eagerly-awaited personalized dietary recommendations, either from the prevention or treatment of different diseases point of view. It is, therefore, essential to gather more information from studies which, from the nutrigenetic point of view, analyze gene–diet interactions in the different intermediate and final phenotypes of diseases. The ideal situation would be to have results available from randomized and controlled clinical trials. Results on gene–diet interactions obtained from large cohorts, and other types of studies with replication in independent samples, are also of great importance. Similarly, if nutrigenetic findings are accompanied by more mechanistic evidence, integrating other omics, this would be of particular interest. Lastly, another topic of interest is to share strategies for implementing genome-based nutritional interventions. Therefore, this Special Issue of Nutrients, “Nutrigenetics”, will focus on providing evidence of the inter-individual genetic effects of diet in determining diseases phenotypes. We are looking forward to receiving many submissions from outstanding experts on these topics. Experimental papers, meta-analyses, up-to-date review articles, and commentaries are all welcome.
    Schlagwort(e): QH301-705.5 ; Nutritional Genomics ; Precision Nutrition ; Nutrigenetics ; Gene–Diet Interactions ; Nutrigenomics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 87
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: This Special Issue of International Journal of Molecular Sciences (IJMS) is dedicated to the mechanisms mediated at the molecular and cellular levels in response to adverse genomic perturbations and DNA replication stress. The relevant proteins and processes play paramount roles in nucleic acid transactions to maintain genomic stability and cellular homeostasis. A total of 18 articles are presented which encompass a broad range of highly relevant topics in genome biology. These include replication fork dynamics, DNA repair processes, DNA damage signaling and cell cycle control, cancer biology, epigenetics, cellular senescence, neurodegeneration, and aging. As Guest Editor for this IJMS Special Issue, I am very pleased to offer this collection of riveting articles centered on the theme of DNA replication stress. The blend of articles builds upon a theme that DNA damage has profound consequences for genomic stability and cellular homeostasis that affect tissue function, disease, cancer, and aging at multiple levels and through unique mechanisms. I thank the authors for their excellent contributions, which provide new insight into this fascinating and highly relevant area of genome biology.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; Werner Syndrome ; n/a ; A549 cells ; epigenetic ; neurodegeneration ; Genome integrity ; adaptation ; cellular senescence ; genome instability ; Werner Syndrome Protein ; lipofuscin ; cell cycle checkpoints ; exonuclease 1 ; template-switching ; energy metabolism ; mutation frequency ; DNA replication ; fork regression ; motor neuron disease ; Microsatellites ; Alzheimer’s disease ; chromatin remodeler ; repair of DNA damage ; AP site analogue ; mutagens ; replication timing ; Thermococcus eurythermalis ; nucleolar stress ; gene expression ; mutations spectra ; origin firing ; Fanconi Anemia ; superfamily 2 ATPase ; DNA translocation ; DNA repair ; SSB signaling ; homologous recombination ; common fragile sites ; 8-chloro-adenosine ; replication ; genome stability ; mutagenicity ; fork reversal ; multiple sclerosis ; non-B DNA ; protein stability ; heterogeneity ; ubiquitin ; SenTraGorTM (GL13) ; replication restart ; EdU ; ?-arrestin ; NER ; aging ; SSB end resection ; oxidative stress ; ATR ; dormant origins ; R loops ; DNA damage response ; Difficult-to-Replicate Sequences ; DNA double-strand repair ; endonuclease IV ; ALS ; double strand break repair ; premature aging ; replication stress ; EXO1 ; POL? ; translesion synthesis ; strand displacements ; G2-arrest ; DNA replication pattern ; SSB repair ; genome integrity ; G protein-coupled receptor kinase interacting protein 2 (GIT2) ; MMR ; replicative stress ; senolytics ; spacer ; interactome ; ATR-Chk1 DDR pathway ; C9orf72 ; replication fork restart ; translesion DNA synthesis ; DNA damage ; mismatch repair ; DNA replication stress ; DNA helicase ; Polymerase kappa ; DNA fiber assay ; H1299 cells ; TLS ; APE2 ; ageing ; cell death ; chromosome ; TopBP1 ; barley ; clock proteins ; post-translational modification ; 8-oxoG ; S phase ; ataxia telangiectasia mutated (ATM) ; G protein-coupled receptor (GPCR) ; Polymerase eta ; cancer ; G protein-coupled receptor kinase (GRK) ; helicase ; genomic instability ; Parkinson’s disease ; nucleotide excision repair ; SupF ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 88
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Food quality, including dietary quality and diversity, is as essential to human health as air is to human life. In addition, other healthy lifestyle factors, including a healthy body mass index, regular exercise, no smoking, and sufficient sleep duration, are associated with a lower incidence of chronic non-communicable diseases and longer life expectancy. More importantly, maternal healthy lifestyle factors are also associated with a substantially reduced risk of chronic diseases in their offspring. Childhood is a critical period for the development of a healthy lifestyle and the prevention of chronic diseases in adulthood. However, the prevalence of childhood obesity is increasing and unhealthy lifestyles are becoming an epidemic, posing a potential future burden of adult chronic disease. The aim of this Special Issue is to identify and assess dietary factors, including dietary diversity and specific nutrients/phytochemicals, as well as other healthy lifestyle factors, in the prevention and management of childhood chronic diseases. Additionally, we want to identify gaps and tools that could help with the assessment of children’s health. We wanted to encourage all researchers who work in this field to submit original research, reviews, systematic reviews, and meta-analyses to this Special Issue to broaden our knowledge and pave the way for new research directions.
    Schlagwort(e): preschool children ; nutritional status ; eating habits ; Mediterranean diet ; Split-Dalmatia County ; fruit consumption ; lipid ; dyslipidemia ; children and adolescents ; China ; child ; diet quality ; caregiver perception ; CCDI ; dietary fat ; polyunsaturated fatty acid ; monounsaturated fatty acid ; puberty timing ; soy food ; obesity ; hypertension ; child and adolescent health ; food marketing ; policy research ; diet ; kindergarten ; menus ; nutritional errors ; children ; blood pressure ; single-child status ; lifestyle behaviors ; birth cohort ; prospective study ; maternal dietary pattern ; neurodevelopment ; malnutrition ; overnutrition ; fruit and vegetable intake ; potassium intake ; renal damage ; leptin ; preterm neonate ; intrauterine growth restriction (IUGR) ; growth trajectories ; children health prognosis ; diet quality questionnaire ; food groups ; sentinel foods ; dietary diversity ; sedentary behavior ; metabolic syndrome ; preterm ; prebiotics ; glycomacropeptide ; metagenomics ; breastfeeding ; obesity phenotypes ; healthy lifestyle ; baby food ; food contaminant ; toxic elements ; food exposure ; children safety ; children’s health ; arsenic ; cadmium ; mercury ; lead ; latent class analysis ; mediation analysis ; health-related behavior ; cohort ; health-related quality of life ; Swedish Healthy Eating Index for Adolescents 2015 (SHEIA15) ; Riksmaten Adolescents Diet Diversity Score (RADDS) ; inositol ; myo-inositol ; D-chiro-inositol ; gestational diabetes mellitus ; insulin resistance ; randomized controlled trial ; meta-analysis ; screeners ; nutrition ; physical activity ; sedentary behaviour ; lifestyle risk ; COVID-19 ; dietary balance ; Japan ; mealtime regularity ; lifestyle ; electronic devices ; household ; fast food ; adolescents ; dietary behavior ; family ; childhood asthma ; innate immunity ; fruit and vegetables ; carotenoids ; cardio-metabolic risk factors ; birth weight ; parents’ educational level ; parents’ occupational level ; birthweight ; adiposity ; cardiorespiratory fitness ; cholesterol ; lifestyle intervention ; KIDMED test ; kidney impairment ; Diet Quality Questionnaire ; global dietary recommendations ; overweight ; child-nutrition disorders ; prediabetic state ; nutrition therapy ; Mediterranean ; rural health ; complementary feeding ; determinants ; infant feeding ; Thailand ; young child ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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  • 89
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Tissue engineering and regenerative medicine is a rapidly evolving research field which effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular populations using several tissue engineering approaches, such as the decellularization method. Indeed, the decellularization method aims to develop a cell-free biologic scaffold while keeping the extracellular matrix (ECM) intact. Furthermore, biologic scaffolds have been investigated for their in vitro potential for whole organ development. Currently, clinical products composed of decellularized matrices, such as pericardium, urinary bladder, small intestine, heart valves, nerve conduits, trachea, and vessels, are being evaluated for use in human clinical trials. Tissue engineering strategies require the interaction of biologic scaffolds with cellular populations. Among them, stem cells are characterized by unlimited cell division, self-renewal, and differentiation potential, distinguishing themselves as a frontline source for the repopulation of decellularized matrices and scaffolds. Under this scheme, stem cells can be isolated from patients, expanded under good manufacturing practices (GMPs), used for the repopulation of biologic scaffolds and, finally, returned to the patient. The interaction between scaffolds and stem cells is thought to be crucial for their infiltration, adhesion, and differentiation into specific cell types. In addition, biomedical devices such as bioreactors contribute to the uniform repopulation of scaffolds. Until now, remarkable efforts have been made by the scientific society in order to establish the proper repopulation conditions of decellularized matrices and scaffolds. However, parameters such as stem cell number, in vitro cultivation conditions, and specific growth media composition need further evaluation. The ultimate goal is the development of “artificial” tissues similar to native ones, which is achieved by properly combining stem cells and biologic scaffolds and thus bringing them one step closer to personalized medicine. The original research articles and comprehensive reviews in this Special Issue deal with the use of stem cells and biologic scaffolds that utilize state-of-the-art tissue engineering and regenerative medicine approaches.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; nerve conduit ; tissue engineering ; regenerative medicine ; mixed lymphocyte reaction ; histological images ; future scaffold engineering ; multiparameter ; 3DPVS ; MSCs ; Wnt signaling ; Mesenchymal Stromal Cells ; factorial design ; novel scaffold ; Wharton’s Jelly tissue ; stem cells ; umbilical arteries ; SDS ; platelet rich plasma ; TGF? signaling ; traditional scaffold ; pluripotency and commitment ; tissue engineered construct ; HLA-G ; CHAPS ; platelets ; proteomic analysis ; vibrating nature of universe. ; VS55 ; cell culture ; FGF signaling ; evolution of scaffold ; dynamicity and dimensionality ; fibrin gel ; scaffold classification ; decellularization ; vitrification ; seven-folder logics ; IIEF-5 questionnaire ; TGF-?1 ; erectile dysfunction ; human induced pluripotent stem cells ; iPSCs ; scaffolds ; Barret’s esophagus ; nerve regeneration ; long term storage ; laws of system evolution ; scaffold categorization ; platelet lysate ; 3D scaffold ; esophagus ; language of relativity ; cord blood units ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 90
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging zoonotic coronavirus. First identified in 2012, MERS-CoV has caused over 2460 infections and a fatality rate of about 35% in humans. Similar to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV likely originated from bats; however, different from SARS-CoV, which potentially utilized palm civets as its intermediate hosts, MERS-CoV likely transmits to humans through dromedary camels. Animal models, such as humanized mice and nonhuman primates, have been developed for studying MERS-CoV infection. Currently, there are no vaccines and therapeutics approved for the prevention and treatment of MERS-CoV infection, although a number of them have been developed preclinically or tested clinically. This book covers one editorial and 16 articles (including seven review articles and nine original research papers) written by researchers working in the field of MERS-CoV. It describes the following three main aspects: (1) MERS-CoV epidemiology, transmission, and pathogenesis; (2) current progress on MERS-CoV animal models, vaccines, and therapeutics; and (3) challenges and future prospects for MERS-CoV research. Overall, this book will help researchers in the MERS-CoV field to further advance their work on the virus. It also has important implications for other coronaviruses as well as viruses outside the coronavirus family with pandemic potentials.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; cell–cell fusion ; hDPP4 ; n/a ; therapeutics ; animal models ; HCoV-229E ; Drivers ; camels ; rabbits ; SARS-CoV ; MERS-CoV ; MVA vaccine ; transmission ; RBD ; MERS-CoV nucleocapsid protein ; complement ; animal model ; pseudotyped virus ; combination ; MERS-coronavirus ; peptide ; mouse model ; spike protein ; receptor-binding domain ; prevention and treatment ; coronaviruses ; coronavirus spike glycoprotein ; therapeutic antibodies ; vaccine platforms ; mutation ; severe acute respiratory syndrome coronavirus ; pathogenesis ; fusion inhibitor ; Coronavirus ; murine CD8+ T cell epitope ; lipidomics ; authentic virus ; correlates of immunity ; vaccines ; neutralizing monoclonal antibodies ; Middle East respiratory syndrome coronavirus ; small-molecule inhibitor ; Middle East Respiratory Syndrome Virus ; DPP4 ; pyroptosis ; cross-neutralization ; inflammation ; Qatar ; spike proteins ; One Health ; HKU4 ; nanobodies ; mechanism of action ; neutralizing antibody ; host factors ; UHPLC–MS ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 91
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Many of the most common diseases are influenced by a combination of multiple factors, which include environmental effectors as well as genetic and epigenetic variations. Therefore, these diseases are grouped under the term “complex” diseases because, from the point of view of genetics, they cannot be explained by simple Mendelian inheritance. The aim of this special issue was to identify genetic and epigenetic factors involved in such diseases in order to improve not only the knowledge of risk factors for those diseases, which could be of help for prevention, but also the understanding and characterization of each disease and to optimize and personalize the treatment.
    Schlagwort(e): chromatin remodeling ; circular RNA ; DNA methylation ; histone modification ; non-coding RNA ; oncogenes ; tumor suppressor genes ; tumor virus ; chronic lymphocytic leukemia ; CLL ; SF3B1 mutation ; NOTCH ; IKAROS ; syncope ; vasovagal syncope ; genetics ; complex disorders ; susceptibility ; twin studies ; family studies ; candidate gene association studies ; genome-wide studies ; acute myeloid leukemia ; pediatric ; trio sequencing ; germline cancer predisposition ; POT1 ; shelterin complex ; psoriasis ; psoriatic arthritis ; NF-κB ; comorbidities ; genetic architecture ; SKP1 ; CUL1 ; RBX1 ; SKP2 ; FBXW7 ; FBXO5 ; SCF complex ; genome instability ; chromosome instability ; cancer ; VDBP ; vitamin D binding protein ; rs7041 ; rs4588 ; bone density ; diabetes ; obesity ; COPD ; pulmonary tuberculosis ; SNP ; MD ; PD ; CD33 ; Alzheimer’s disease ; sialic acid ; phagocytosis ; KLF14 ; body shape indices ; metabolic traits ; differential effect ; genetic variants ; resistin ; soluble suppression of tumorigenicity 2 ; weighted genetic risk score ; Taiwan Biobank ; coronary artery disease ; all-cause mortality ; major adverse cardiac events ; acute lymphoblastic leukemia ; RAD21 ; cohesin complex ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
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  • 92
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Renal cancer is a health problem of major concern worldwide. Although tyrosine kinase inhibitors and immune check-point blockade treatments, alone or in combination, are giving promising results, failures are quite frequent due to intratumor heterogeneity and to the acquisition of drug resistance. The spectrum of renal cell carcinoma subtypes is wide. Up to 70–80% of renal tumors are clear cell renal cell carcinomas, a clinically aggressive tumor subtype linked to VHL gene inactivation. Next in frequency, the papillary renal cell carcinoma category encompasses an intricate puzzle of classic and newly described entities with poorly defined limits, some of them pending definite clarification. Likewise, the chromophobe–oncocytoma duality, the so-called hybrid tumors and oncocytic neoplasms, remain to be well profiled. Finally, a growing list of very uncommon renal tumors linked to specific molecular signatures fulfill the current portrait of renal cell neoplasia. This Special Issue of Cancers regards RCC from very different perspectives, from the intimate basic mechanisms governing this disease to the clinical practice principles of their diagnoses and treatments. The interested reader will have the opportunity to contact with some of the most recent findings and will be updated with excellent reviews.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; N-glycomapping ; n/a ; SMAD proteins ; patient survival ; pro-IL-1? ; survival prediction ; inflammation markers ; tumor migration ; prognostic factors ; practical approach ; circular RNAs in a clinico-genomic predictive model ; glycomarkers ; review ; nephrectomy ; uric acid ; VEGF inhibitors ; metabolic reprogramming ; collecting duct carcinoma ; curcumin ; metabolome profiling ; identification of circular RNAs ; IL-2 ; experimental validation of circular RNA ; Raf/MEK/ERK ; HOT ; PI3K/Akt/mTOR ; pentose phosphate pathway ; kidney cancer ; LOT ; mutation ; RCC ; polybromo-1 ; pale cell ; MMP-9 ; gene expression ; recurrence free survival ; chromosomal loss ; IL-1? ; chronic kidney disease ; glutathione transferase omega 2 ; label-free ; glutathione transferase omega 1 ; emerging entity ; copy number alteration ; FOXO3 ; predictive role ; tumor slice culture ; tyrosine kinase inhibitors ; PPP ; ESC ; CDKN1A expression ; metastasis ; PD-L1 ; diagnostic and prognostic markers ; EVI1 ; copy number loss ; RNA sequencing ; NK cells ; glutathione metabolism ; clear cell renal cell carcinoma ; renal cell cancer ; proliferation ; eosinophilic variant ; Xp11 translocation renal cell carcinoma ; prognosis ; invasion ; immune infiltration ; IL4R? ; FISH ; 11) translocation renal cell carcinoma ; tumor microenvironment ; metabolome ; hyperosmolality ; toxicity ; ALK ; drug sensitivity ; t(6 ; copy number analysis ; urine ; genetic association ; polymorphism ; solute carrier proteins ; kidney ; metastatic ccRCC ; molecular genetic features ; recurrence-free survival ; chromophobe renal cell carcinoma ; unclassified renal tumor ; overall survival ; mTOR inhibitors ; mTOR ; JAK2 ; von Hippel–Lindau ; miR-155-5p ; glycoproteomics ; PBRM1 ; miR-133b ; survival ; TFE3 ; TFEB ; oncocytic renal tumor ; immune checkpoint inhibitors ; biomarker ; MMP10 ; TCGA ; ghrelin ; EMT like ; checkpoint inhibitors ; MiT family translocation renal cell carcinoma ; gene signature ; sarcomatoid ; transforming growth factor beta ; clear cell Renal Cell Carcinoma ; tumor adhesion ; renal cancer ; unclassified renal cell carcinoma ; Papillary renal cell carcinoma (pRCC) ; miR-146a-5p ; renal cell ; everolimus ; integrins ; cytoreductive nephrectomy ; immunotherapy ; predictive factors ; immunohistochemistry ; MTA2 ; IL13R?1 ; targeted therapy ; intratumour heterogeneity ; aurora A ; TCA cycle ; AMP-activated protein kinases ; cancer-specific survival ; programmed death-ligand 1 ; efficacy ; renal cell carcinoma ; anaplastic lymphoma kinase rearrangement ; TFEB-amplified renal cell carcinoma ; statins ; cancer immunotherapy ; microRNA ; new entity ; proteome profiling ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 93
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Salt stress is one of the most damaging abiotic stresses because most crop plants are susceptible to salinity to different degrees. According to the FAO, about 800 million Has of land are affected by salinity worldwide. Unfortunately, this situation will worsen in the context of climate change, where there will be an overall increase in temperature and a decrease in average annual rainfall worldwide. This Special Issue presents different research works and reviews on the response of plants to salinity, focused from different points of view: physiological, biochemical, and molecular levels. Although an important part of the studies on the response to salinity have been carried out with Arabidopsis plants, the use of other species with agronomic interest is also notable, including woody plants. Most of the conducted studies in this Special Issue were focused on the identification and characterization of candidate genes for salt tolerance in higher plants. This identification would provide valuable information about the molecular and genetic mechanisms involved in the salt tolerance response, and it also supplies important resources to breeding programs for salt tolerance in plants.
    Schlagwort(e): QH301-705.5 ; QD415-436 ; Q1-390 ; soluble nutrients ; transcription factor ; n/a ; CDPK ; salicylic acid ; antioxidant enzymes ; light saturation point ; phytohormone ; ion homeostasis ; antioxidant systems ; photosynthesis ; Chlamydomonas reinhardtii ; high salinity ; nitric oxide ; poplars (Populus) ; root activity ; abiotic stresses ; transcriptional activator ; germination ; ABA ; transcriptome ; mandelonitrile ; redox homeostasis ; association mapping. ; redox signalling ; osmotic stress ; flax ; strigolactones ; salt tolerance ; nucleolin ; CaDHN5 ; photosystem ; EST-SSR ; NMT ; Sapium sebiferum ; Gossypium arboretum ; SOS ; Brassica napus ; SnRK2 ; HKT1 ; grapevine ; transcription factors ; cucumber ; underpinnings of salt stress responses ; abiotic stress ; Arabidopsis thaliana ; RNA-seq ; halophytes ; single nucleotide polymorphisms ; dehydrin ; J8-1 plum line ; chlorophyll fluorescence ; natural variation ; hydrogen peroxide ; salt stress ; lipid peroxidation ; ROS detoxification ; ROP ; molecular mechanisms ; cell membrane injury ; booting stage ; ascorbate cycle ; banana (Musa acuminata L.) ; iTRAQ quantification ; ROS ; Na+ ; Capsicum annuum L. ; bZIP transcription factors ; multiple bioactive constituents ; NaCl stress ; physiological changes ; VOZ ; transcriptional regulation ; genome-wide identification ; Apocyni Veneti Folium ; impairment of photosynthesis ; salt-stress ; Oryza sativa ; reactive oxygen species ; lipid accumulation ; polyamines ; multivariate statistical analysis ; DEUs ; salinity ; TGase ; Salt stress ; Prunus domestica ; proteomics ; Arabidopsis ; RNA binding protein ; rice ; glycophytes ; SsMAX2 ; drought ; genome-wide association study ; transcriptome analysis ; signal pathway ; melatonin ; MaROP5g ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 94
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Mathematical and computational modeling approaches in biological and medical research are experiencing rapid growth globally. This Special Issue Book intends to scratch the surface of this exciting phenomenon. The subject areas covered involve general mathematical methods and their applications in biology and medicine, with an emphasis on work related to mathematical and computational modeling of the complex dynamics observed in biological and medical research. Fourteen rigorously reviewed papers were included in this Special Issue. These papers cover several timely topics relating to classical population biology, fundamental biology, and modern medicine. While the authors of these papers dealt with very different modeling questions, they were all motivated by specific applications in biology and medicine and employed innovative mathematical and computational methods to study the complex dynamics of their models. We hope that these papers detail case studies that will inspire many additional mathematical modeling efforts in biology and medicine
    Schlagwort(e): QH301-705.5 ; Q1-390 ; predator-prey model ; n/a ; uncertainty quantification ; identification of DNA-binding proteins ; chemostat ; numerical characterization ; differential equations ; uniform persistence ; spotting ; 2-combination ; wildfire ; chronic myeloid leukemia ; combination therapy ; liquid-solid-porous media seepage coupling ; dynamic model ; obesity ; epidermis ; articular cartilage ; androgen deprivation therapy ; quorum sensing ; mechano-electrochemical model ; bifurcations ; bacterial competition ; global stability ; cartilage degeneration ; flocculation ; dynamical system ; transport equations ; bootstrapping ; stationary distribution ; algae growth models ; hemodynamic model ; delay ; Raphidocelis subcapitata ; cartilage loading ; Daphnia magna ; cell-based vector ; switched harvest ; hepatitis B ; rich dynamics ; spotting distribution ; asymptotic theory ; tyrosine kinase inhibitors ; phylogenetic analysis ; immune response ; microcirculation load ; graphical representation ; intraguild predation ; numerical simulation ; bacterial inflammation ; data fitting ; immunomodulatory therapies ; drug therapy ; delay differential equations (DDE) ; global asymptotic stability ; model comparison tests ; optimal control ; generalized pseudo amino acid composition ; random perturbations ; limit cycle ; prostate cancer ; mathematical model ; mathematical modeling ; persistence ; equilibrium points ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 95
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Maternal and infant nutrition has been on the global agenda as central to health, sustainable development, and progress in low- and middle-income countries. Micronutrients, which play a major role in the metabolism of macronutrients, cellular metabolism, and organ development of the fetus, are important for maintaining pregnancy and fetal growth. Besides, during pregnancy, there is an elevated demand for micronutrients, the excess or deficiency of which can result in an increased risk of pregnancy complications and adverse birth outcomes. As China is a rapidly developing country with a large population, micronutrient status and its influence on maternal and infant health have always been a concern. This Special Issue aimed to estimate the influence that micronutrients can have on maternal and infant health, which provides evidence for clinical interventions and government nutrition-related policies. Additionally, this Special Issue provides study directions for research on micronutrients among pregnant women and infants. In this Special Issue, original research articles and reviews were welcomed. Research areas include, but are not limited to, the following: Micronutrient status of pregnant women and infants; Relationship between micronutrients and pregnancy complications as well as birth outcomes.
    Schlagwort(e): gestational diabetes mellitus ; subtypes ; gene polymorphism ; vitamin D ; manganese ; cord blood ; birth outcomes ; childhood growth ; dietary pattern ; B vitamins ; pregnancy ; birth weight ; small-for-gestational-age ; reduced rank regression ; maternal hemoglobin concentration ; neonatal birth weight ; LBW ; SGA ; nonlinear association ; prospective study ; preeclampsia ; systematic review ; meta-analysis ; zinc ; copper ; selenium ; congenital heart defects ; vitamin E ; gestational diabetes mellitus (GDM) ; large-for-gestational-age (LGA) ; cord serum 25(OH)D level ; vitamin D deficiency ; urinary selenium ; repeated measurements ; SNPs ; hypertensive disorders of pregnancy ; prospective cohort study ; hemoglobin ; iron supplementary ; maternal hemoglobin ; neonatal ; SGA/LBW ; LGA/macrosomia ; passive smoking ; spontaneous abortion ; co-exposure ; Vitamin D ; deficiency ; thyroid-stimulating hormone ; free thyroxine ; free triiodothyronine ; vitamin A ; retinol ; human milk ; full-term infant ; lactation stage ; nickle ; trace elements ; restricted cubic spline ; LASSO regression ; quantile g-computation ; BKMR models ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
    Sprache: Englisch
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  • 96
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The year 2019 has been prolific in terms of new evidence regarding the effects of coffee and caffeine consumption on diverse aspects of human functioning. This book collects 20 high-quality manuscripts published in Nutrients that include original investigation or systematic review studies of the effects of caffeine intake on human performance and health. The diversity of the articles published in this Special Issue highlights the extent of the effects of coffee and caffeine on human functioning, while underpinning the positive nature of most of these effects. This book will help with understanding why the natural sources of caffeine are so widely present in the nutrition behaviors of modern society.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; NAT ; n/a ; supplementation ; EEG–EMG coherence ; muscle function ; tea ; fatigue ; ergogenic ; adrenal gland ; skeletal muscle ; xanthine oxidase ; placebo ; CMJ ; efficiency ; colorectal cancer ; rat ; pregnancy ; coffee/caffeine ; Wingate ; 1RM test ; supplement ; actigraphy ; athletic ; systematic review and meta-analysis ; women ; consumption motives ; resistance training ; cancer prevention ; sport supplement ; exercise ; DOMS ; placebo effect ; sprint performance ; power ; behavior ; belief ; health ; perceptions ; exercise performance ; ergogenic aid ; electromyography ; ergogenic effect ; corticosterone ; metabolome ; mood state ; muscle contraction ; strength ; energy drink ; repetition ; responders ; perception ; anaerobic ; CYP450 ; puberty ; energy drinks ; isokinetic testing ; individual responses ; phenotyping ; nutrition ; time under tension ; menstrual cycle ; exercise training ; RPE ; ergogenic substances ; upper limb ; elite athlete ; recovery ; speed ; epidemiology ; caffeine ; sex-difference ; bench press ; pharmacokinetics ; sport performance ; ergogenic aids ; expectancy ; consumer ; football ; newborn ; velocity ; metabolites ; performance ; coffee ; prospective studies ; resistance exercise ; sport ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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    Standort Signatur Erwartet Verfügbarkeit
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  • 97
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Nowadays, one of the main objectives of the fruit and vegetable industry is to develop innovative novel products with high quality, safety, and optimal nutritional characteristics in order to respond, with efficiency, to increasing consumer expectations. Various unconventional technologies (e.g., pulsed electric field, pulsed light, ultrasound, high pressure, and microwave drying) have emerged and enable the processing of fruits and vegetables in a way that increases their stability while preserving their thermolabile nutrients, flavour, texture, and overall quality. Some of these technologies can also be used for waste and byproduct valorisation. The application of fast noninvasive methods for process control is of great importance for the fruit and vegetable industry. The following Special Issue “Safety, Quality, and Processing of Fruits and Vegetables” consists of 11 papers which represent a high-value contribution to the existing knowledge on safety aspects, quality evaluation, and emerging processing technologies for fruits and vegetables.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; blanching ; valorization ; dielectric spectroscopy ; antioxidant activity ; postharvest physiology ; eco-extraction ; thermal properties ; cranberries ; safety ; healthy food ; reducing sugar ; pulsed electric field ; dehydration ; high voltage electrical discharge ; fluence ; sonication ; raspberry ; permittivity ; unconventional processing ; pectin methyl esterase ; isotherms ; extraction ; sucrose ; sustainability ; mango juice ; quality ; lycopene ; hot air drying ; waste reduction ; birefringence ; processing ; thermo-sonication ; green solvents ; sustainable production ; emerging technologies ; reduced pressure ; color ; fruit ; ultra-high pressure ; phenolic compounds ; pulsed electric fields ; tomato ; vegetable ; chip processing ; vegetables ; olive leaves extracts ; red beet ; enzyme susceptibility ; cold storage ; potato ; potato starch ; freeze-drying ; pulsed light ; reconditioning ; candying ; non-thermal treatment ; convective drying ; color change ; texture ; physicochemical property ; gallic acid ; high pressure ; bioactive compounds ; microscopy ; shrinkage ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 98
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Selected studies focussing on various aspects of the evaluation of marine larval settlement on both natural and artificial surfaces, including those on pro-fouling and anti-fouling systems, have been collected for advancing our understanding of larvae–surface interactions. Biofouling is a large problem worldwide since it often causes severe damage to submerged structures, but it also leads to the formation of a well-structured community on natural hard substrata characterised by ecological succession and can be considered an important source of biodiversity. Therefore, the influence of a substratum’s physico-chemical interactions on the settlement of various organisms of the macrofouling community represents an essential factor in choosing an appropriate artificial surface for application in a variety of coastal marine ecosystems. This reprint will certainly be greatly beneficial with respect to addressing the challenges of future innovative eco-engineering designs, yielding the best solutions for industrial biofouling protection and coastal ecosystem preservation.
    Schlagwort(e): barnacles ; larvae ; anatomy ; adhesion ; electron microscopy ; biofouling ; environmental protection ; coastal waters ; larval settlement-biofilm interactions ; Notobalanus flosculus ; Chile ; chimerism ; settlement ; planulae ; neutral red ; aggregation ; Stylophora pistillata ; larval behavior ; larval settlement ; substrate preference ; water wettability ; moth-eye structure ; MOSMITETM ; silicone paradox ; ultraviolet light ; color ; surface material ; exposure interval ; Fucus ; rock type ; attachment ; mineral composition ; adhesive papillae ; adultation ; Botryllus schlosseri ; Ciona intestinalis ; tunicates ; ascidians ; antifouling paints ; booster biocides ; EC50 ; fouling settlement ; larval toxicity ; metamorphosis ; bivalves ; scallops ; spat ; artificial collectors ; recruitment ; mariculture ; non-indigenous species ; Adriatic Sea ; biocide antifoulant ; eco-friendly antifoulant ; antioxidative defence ; Mytilus galloprovincialis ; sustainable development goals ; agenda 2030 ; development ; enzyme histochemistry ; haematopoiesis ; haemocytes ; ultrastructure ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Sprache: Englisch
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  • 99
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. This special issue of the International Journal of Molecular Sciences contains a collection of articles by colleagues of Antonius (Ton) Gerardus Rolink (19/04/1953-06/08/2017) and honors Ton’s life and profound knowledge of and huge contribution to science. Ton participated in an FP7 Marie Curie Initial Training Network called DECIDE, and partners have submitted articles for this Special Issue. Scientists outside this network have also submitted articles. The articles examine various aspects of how the hematopoietic stem-cell gives rise to the different types of blood and immune cells. These include decision-making by the hematopoietic stem cell and the importance of controlling events within cells and the niches the cell resides in. New insights into these processes at the basic scientific level have given rise to an emerging new model for the development of blood cells. In turn, changes to our understanding of this process have led to new and exciting propositions regarding what goes wrong during the early stages of the development of leukemia.
    Schlagwort(e): QH301-705.5 ; RC254-282 ; stem cells ; cell differentiation ; leukaemia ; haematopoiesis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 100
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-03-28
    Beschreibung: Taxonomy, floristic studies, biosystematics, classical taxonomy, and modern taxonomic advances; phylogenomics, phylogenetics, and biogeography, including phylogeography; and the description of well-documented new taxonomic taxa, monographs, and taxonomic revisions. It incorporates data from classical morphology (including both macro and micro morphology), molecular study, anatomy and ecology, distribution, molecular evolution, evolutionary development, population biology, conservation biology, evolutionary ecology, paleobiology, and related methods and theories in recent development in systematics and floristic studies.
    Schlagwort(e): species boundaries ; species concept ; taxonomic relationship ; conservation ; future climate change ; ecology ; Mimosoideae taxa ; pollen morphology ; taxonomic relevance ; light microscopy ; scanning electron microscopy ; Dalbergia ; Early Miocene ; ITS ; long-distance dispersal ; matK ; monophyletic ; rbcL ; flora ; environmental variable ; multivariate analysis ; soil moisture ; Shangla district ; Pakistan ; coastal and insular vegetation ; protected areas ; coastal wetland ; freshwater swamp ; mangrove ; lowland dipterocarp forest ; exine sculpturing ; palynomorph ; pollen grains ; Arabian Peninsula ; chorology ; flora of Saudi Arabia ; flora of West Asia ; Hijazi Mountains ; Jabal Al-Ward ; Tabuk ; Saudi Arabia ; bioclimatology ; agronomy ; olive cultivation ; climate change ; vegetation cover ; antioxidant capacity ; bioactive compounds ; endangered medicinal species ; high altitude environment ; oxidative stresses ; protectorate ; fernlike plant ; new syntaxa ; Ophioglossaceae ; phytosociological study ; palynoflora ; taxonomic ; microscopy ; systematics ; vegetation’s origin ; Turkish flora ; surface ; clustering analysis (CA) ; principle component analysis (PCA) ; Gas chromatography-mass spectrometry (GC-MS) ; leaf ; morphometry ; morphotype ; Ricinus communis ; SEM ; stomata ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Sprache: Englisch
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