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  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry  (189)
  • Chemistry
  • GEOPHYSICS
  • Inorganic Chemistry
  • ddc:330
  • IntechOpen  (194)
  • Springer Nature  (16)
  • Silver Spring, MD
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  • 1
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    Biophysical Chemistry (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Biophysical chemistry is one of the most interesting interdisciplinary research fields. Some of its different subjects have been intensively studied for decades. Now the field attracts not only scientists from chemistry, physics, and biology backgrounds but also those from medicine, pharmacy, and other sciences. We aimed to start this version of the book Biophysical Chemistry from advanced principles, as we include some of the most advanced subject matter, such as advanced topics in catalysis applications (first section) and therapeutic applications (second section). This led us to limit our selection to only chapters with high standards, therefore there are only six chapters, divided into two sections. We have assumed that the interested readers are familiar with the fundamentals of some advanced topics in mathematics such as integration, differentiation, and calculus and have some knowledge of organic and physical chemistry, biology, and pharmacy. We hope that the book will be valuable to graduate and postdoctoral students with the requisite background, and by some advanced researchers active in chemistry, biology, biochemistry, medicine, pharmacy, and other sciences.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 2
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    Essential Oils (2024)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: In recent years, great progress has been made in the field of essential oils as scientific research has revealed new insights into the biological benefits, healing properties, and other uses. Interest in their use in various industries, such as medicine, agriculture, food, and cosmetics, has increased. Essential oils have found their place in many applications, thus fueling a wave of scientific research and industrial applications. This book explores these recent developments in detail, revealing new perspectives and applications of essential oils. It combines historical knowledge with the latest research to provide a comprehensive overview of the field. By exploring the ancient legacy of aromatic plants and their traditional medicinal uses, as well as delving into the latest research and industrial applications, this book provides a comprehensive understanding of essential oils and their potential.
    Keywords: thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 3
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    Chemistry and Biological Activity of Steroids (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 4
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    Mineralogy (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Mineralogy includes thirteen chapters that discuss the methodology of specific mineralogical methods, the composition of minerals from different igneous rocks, and the composition of minerals from different sedimentary rocks.It contains detailed mineralogical studies from Africa, Asia, and Europe. Chapters present different scientific mineralogical methods and detailed descriptions of minerals from different magmatic and sedimentary rocks.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNV Chemistry of minerals, crystals and gems
    Language: English
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  • 5
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    Amino Acid (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Amino Acid - New Insights and Roles in Plant and Animal provides useful information on new aspects of amino acid structure, synthesis reactions, dietary application in animals, and metabolism in plants. Section 1 includes chapters that describe the therapeutic uses, antiallergic effects, new aspects in the D-amino acid structure, historical background of desmosines, and stereoselective synthesis of ?-aminophosphonic acids. Section 2 presents the role of amino acids in plants, which includes new insights and aspects of D-amino acids, metabolism and transport in soybean, changes during energy storage compound accumulation of microalgae, and determination of amino acids from natural compounds. Section 3 describes the chapters on methodologies and requirement of dietary amino acids for Japanese quails, laying hens, and finishing pigs. The final chapter identifies potential importance of glutathione S-transferase activity for generating resistance to triclabendazole in Fasciola hepatica.
    Keywords: amino acids, biomarkers, bacteria, microalgae, phytochemicals, physiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 6
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    Benzimidazole (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Benzimidazole is a comprehensive survey of the known and new methods of benzimidazole synthesis, the spectral and theoretical aspects of existing benzimidazole derivatives, and the anticancer properties of a new class of benzimidazole derivatives. This book examines aspects and newer mechanisms of benzimidazoles containing heterocyclic moiety. Chapters report on anticancer properties of benzimidazole derivatives, novel methods of synthesis of benzimidazoles, versatile nature of the benzimidazoles, spectral and theoretical studies of benzimidazole derivatives, and medicinal importance and pharmacological aspects of benzimidazole derivatives.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 7
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    Lipid Peroxidation Research (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Lipid peroxidation is the major molecular mechanism that induces oxidative damage to cell structures and is also involved in the toxicity process that leads to cell death.Lipid peroxidation is a chain reaction initiated by the hydrogen abstraction or addition of an oxygen radical, resulting in the oxidative damage of polyunsaturated fatty acids (PUFA). PUFAs are more sensitive than saturated fatty acids because of the presence of a double bond adjacent to a methylene group that makes the methylene C-H bond weaker and therefore the hydrogen is more susceptible to abstraction. This leaves an unpaired electron on the carbon, forming a carbon-centered radical, which is stabilized by a molecular rearrangement of the double bonds to form a conjugated diene, which then combines with oxygen to form a peroxy-radical.In pathological situations the reactive oxygen and nitrogen species are generated at higher than normal rates, and as a consequence, lipid peroxidation occurs with deficiency of endogenous antioxidants as alpha-tocopherol deficiency or reduced glutathione. In addition to containing high concentrations of PUFAs and transition metals, biological membranes of cells and organelles are constantly being subjected to various types of damage.This book presents systematic and comprehensive reviews on free radicals and their involvement in lipid peroxidation with special emphasis on their important role in different diseases.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 8
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    Self-Assembled Molecules – New Kind of Protein Ligands: Supramolecular Ligands (2021)
    Springer Nature
    Details
    Publication Date: 2024-04-05
    Description: The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but “naturally irreversible” complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book.
    Keywords: QD415-436 ; ligands ; congo red amyloids ; immunotargeting techniques ; intramolecular immunological signals ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 9
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    Current Topics in Lactation (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Lactation is a fascinating process. Research over the last decade has provided new insights into the regulation of mammary gland development and involution. Lactation is the last step in reproduction, and therefore it is linked to reproduction strategy. Photoperiod species such as sheep, or pseudo-ovulatory (at mid-gestation) species as the rodent Lagostomus maximus, are interesting and unique models to study mammary gland physiology. This book also offers updated insights into the mechanisms that control postlactational involution, therefore also providing information to better understand breast cancer. Small noncoding RNA has opened new understanding in gene regulation. In this regard, our knowledge of mammary gland development and milk secretion has increased extremely. This book provides current scientific information on all these interesting topics. It will certainly be of great benefit to those interested in biomedical sciences.
    Keywords: mammary gland, breast cancer, microrna, melatonin, genome editing, cell death ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 10
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    Chlorophylls (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Chlorophyll, a green pigment present in almost all plants, algae, and cyanobacteria, is a significant biomolecule essential to photosynthesis, the process by which plants convert light into energy. This book provides a comprehensive and easy-to-understand source of information on the latest developments in chlorophyll research. It is a collection of contributions from leading specialists in the subject. Topics discussed include the medicinal uses of chlorophyll, the electronic structure of chlorophyll monomers and oligomers, and chlorophyll estimate from fluorescence vertical profiles in the ocean.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 11
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    Green Chemistry (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Green Chemistry - New Perspectives is at the frontiers of this continuously evolving interdisciplinary science, and publishes research that attempts to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The book covers all aspects of green chemistry, including chemical synthesis, nano synthesis, eco-friendly processes, biomass, extraction techniques, environmental remediation, and energy, making it a unique reference resource. This will continue to encourage scientists around the world to develop novel synthetic methods or improve the existing ones to circumvent some of the problems and favours all aspects of green chemistry. This book is intended for academia, professionals, scientists, as well as graduate and undergraduate students without any geographical limitations.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 12
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    Proteomics Technologies and Applications (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Proteomics Technologies and Applications reviews and describes the nature and application of molecules with proteins or peptides, and elucidates and predicts the possible molecular and physiological causes related to changing proteomic profiles. Chapters target various methods and tools available for analysis, detection, separation, quantification, and localization of cell proteomes of a biological system, which are helpful as biomarkers for various disease prognoses and diagnoses.
    Keywords: mass spectrometry, biomarkers, breast cancer, colorectal cancer, melanoma, glioblastoma ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 13
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    Stem Cell Biology in Normal Life and Diseases (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Stem cells have a prominent role in normal life and also in pathogenesis of disorders. Today, these cells are clinically applicable in hematopoietic stem cell transplantation but expansion of their application in many more disorders needs more work. For safe and effective application of these cells, we need better knowledge of their biology, their interaction with other cells (especially supporting niche cells), growth, maturation and also immigration of stem cells through body in normal and abnormal conditions. Also for clinical application we need to understand better, their separation methods and safe manipulation. This book is written to clarify some aspects of stem cell biology, their characteristics, assessment of damage to cells during ex vivo manipulation and also their role in a model of cancers (chronic myeloid leukemia).
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 14
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    Embryonic Stem Cells (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Embryonic stem cells are one of the key building blocks of the emerging multidisciplinary field of regenerative medicine, and discoveries and new technology related to embryonic stem cells are being made at an ever increasing rate. This book provides a snapshot of some of the research occurring across a wide range of areas related to embryonic stem cells, including new methods, tools and technologies; new understandings about the molecular biology and pluripotency of these cells; as well as new uses for and sources of embryonic stem cells. The book will serve as a valuable resource for engineers, scientists, and clinicians as well as students in a wide range of disciplines.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 15
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    Protein Kinases (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Proteins are the work horses of the cell. As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. This book is a collaborative effort, with contribution from experts in their respective fields, reflecting the spirit of collaboration - across disciplines and borders - that exists in modern science. Here, we review the existing literature and, on occasions, provide novel data on the function of protein kinases in various systems. We also discuss the implications of these findings in the context of disease, treatment, and drug development.
    Keywords: Enzymology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 16
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    Extracellular Vesicles and Their Importance in Human Health (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Extracellular vesicle is a wide term that involves many different types of vesicles. Almost all the cell types studied secrete vesicles to the extracellular environment related to cell - cell communication. Extracellular vesicles have been found in different biological fluids, such as blood, milk, saliva, tears, urine, and cerebrospinal fluid. These vesicles transport different molecules, including mRNA, proteins, and lipids, some of them cell type specific that make them ideal biomarkers in both health and disease conditions. However, their contribution to different conditions is not well understood. The aim of this book is to provide an overview of the extracellular vesicles in the human body, how they are internalized, and their participation in several diseases.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 17
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    Pluripotent Stem Cells (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 18
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    Glutathione System and Oxidative Stress in Health and Disease (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 19
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    Advances in Lipid Metabolism (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This edited volume is a collection of reviewed and relevant research chapters concerning developments within the field of lipid metabolism. It includes scholarly contributions from experts in the field that cover such topics as roles of lipids in cancer, analytical tools for lipid assessment in biological assays, plant lipid metabolism, the effect of nanoparticles on lipid peroxidation in plants, and fatty acid compositions in fermented fish products. This book provides a thorough overview of the latest research efforts by international authors on lipid metabolism, and opens new possible research paths for further novel developments.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 20
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    Phytochemicals in Human Health (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Naturally present bioactive compounds in plants are referred to as "Phytochemicals" and are being studied extensively for their role in human health. Studies have shown that they can have an important role to play in the prevention and management of several human diseases. Recognizing the increasing interest in this area, this book is being published in response to the need for more current information globally about phytochemicals and their role in human health. Chapters of the book are authored by internationally recognized authors who are experts in their respective field of expertise. The chapters represent both original research as well as up-to-date and comprehensive reviews. We are sure that the book will be an important reference source meeting the needs of a wide range of interest groups.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 21
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    Methodological Advances in the Culture, Manipulation and Utilization of Embryonic Stem Cells for Basic and Practical Applications (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Pluripotent stem cells have the potential to revolutionise medicine, providing treatment options for a wide range of diseases and conditions that currently lack therapies or cures. This book describes methodological advances in the culture and manipulation of embryonic stem cells that will serve to bring this promise to practice.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 22
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    Neural Stem Cells and Therapy (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book is a collective work of international experts in the neural stem cell field. The book incorporates the characterization of embryonic and adult neural stem cells in both invertebrates and vertebrates. It highlights the history and the most advanced discoveries in neural stem cells, and summarizes the mechanisms of neural stem cell development. In particular, this book provides strategies and discusses the challenges of utilizing neural stem cells for therapy of neurological disorders and brain and spinal cord injuries. It is suitable for general readers, students, doctors and researchers who are interested in understanding the principles of and new discoveries in neural stem cells and therapy.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 23
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    Carotenoids (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Carotenoids are one of the most widespread pigment groups distributed in nature; more than 700 natural carotenoids have been described so far. These pigments are known for versatile roles they play in living organisms; however, their most pivotal function is involvement in scavenging of reactive oxygen species and photoprotection. In the same time, carotenoids as natural pigments with important biological activities, such as antioxidant and provitamin A activity, have a great potential in the food, feed and pharmaceutical industries. They can be either extracted from plants and algae or synthesized by various microorganisms, including bacteria, yeasts, filamentous fungi and microalgae.
    Keywords: β-carotene, antioxidants, toxicity, cardiovascular disease, stress, microalgae ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 24
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    Hydrolases (2022)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book gives a current review of the links between the structure and function of hydrolases and ligases, as well as ideas for better using these critical enzymes. The book is split into two sections: “Cleavage” and “Ligases.” These enzymes are the biggest and most varied family of enzymes, allowing researchers to investigate the structural variety that underpins their different biological roles. In light of recent scientific advances, there is a desire to examine and update our knowledge of these enzymes’ functional and structural changes.
    Keywords: Enzymology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 25
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    A Critical Evaluation of Vitamin D (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The book A Critical Evaluation of Vitamin D - Basic Overview targets the physiological, biochemical and immunological aspects of vitamin D, including principles, mechanisms and clinical significance. This book covers four sections: ‘Vitamin D on Physical and Physiological Activities’, ‘Vitamin D on Biochemical and Immunological Activities’, ‘Vitamin D on Musculoskeletal and Neurological System’ and ‘Vitamin D on Reproductive System’. Each of these sections is interwoven with the theoretical aspects and experimental techniques of basic and clinical sciences. This book will be a significant source to students, scientists, physicians, healthcare professionals and also other members of this society who are interested in exploring the role of vitamin D in human life. We derive vitamin D from the sunshine, and hence it can also be considered as ‘day’ vitamin.
    Keywords: osteoporosis, vitamin d deficiency, cancer, inflammation, oxidative stress, biomarkers ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 26
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    Innovations in Cell Research and Therapy (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: All living things are comprised of cells. A cell is the building block of complex organisms. All cells contain genetic material. Some cells contain subunits known as organelles that perform specific functions. Protein processing, energy generation, and macromolecular biosynthesis are some of the functions of organelles. Recently, advances in cell biology have elucidated new insights in cellular development and the unique functions of different types of cells. The era of biotechnology is rooted in biologics, and cell biology has delivered novel therapeutic candidates. Personalized medicine has its underpinnings in cell biology. Innovations in Cell Research and Therapy focuses on recent key advances that are transforming health and medical sciences. Understanding fundamental cellular processes, including cellular differentiation, the many applications of stem cells, natural and synthetic approaches for inducing apoptosis, and new insights into organelle biology and macromolecular processing are representative examples of the topics that are addressed in the chapters found in this book.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 27
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    Insights on Antimicrobial Peptides (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Modern medicine is impossible without antibiotics, but global antibiotic usage has led to the development of increasing numbers of multi-drug resistant (MDR) bacteria. Thus, we still have problems with infectious disease treatment despite an arsenal of antibiotics. This has forced researchers to develop new drugs that will be effective against resistant bacteria. Some of these prospective molecules are antimicrobial peptides (AMPs), which are an important component of the innate immune system of various organisms in nature. Currently, more than 3,000 AMPs have been reported with different activities against different bacterial species including resistant phenotype bacteria. AMPs display remarkable structural and functional diversity that is not completely understood. As such, this book presents a comprehensive overview of AMPs and their mechanism of action against MDR bacteria.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 28
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    Metabolomics (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Metabolomics is the methodology and theory to study the metabolome, including targeted approaches based on selected/multiple reaction monitoring (SRM/MRM) and untargeted approaches based on nuclear magnetic resonance (NMR) or mass spectrometry (MS). The metabolome contains all metabolites derived from sugars, lipids, proteins, and nucleic acids in a given biological system, tissue, cell, or body fluid in a metabolic network system. Metabolomic variations directly link to molecular mechanisms of a disease, reliable therapeutic targets, and effective biomarkers for prediction, diagnosis, and prognostic assessment of disease. This book presents new advances in the concept and methodology of metabolomics, as well as applications of metabolomics in the research and practice of medical and life sciences.
    Keywords: biomarkers, drug discovery, metabolites, personalized medicine, transgenic plant, fungus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 29
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    Importance of Oxidative Stress and Antioxidant System in Health and Disease (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Oxidative stress is a major contributor to the etiology of chronic disorders like cancer, diabetes, neurodegenerative diseases, and cardiovascular diseases. Long-term exposure to elevated levels of pro-oxidant substances can lead to structural damage in mitochondrial DNA as well as functional changes in a number of enzymes and cellular components, which can lead to abnormalities in gene expression. Modern lifestyles, which include eating processed food, exposure to a variety of chemicals, and not exercising, are significant factors in the development of oxidative stress. However, the ability of medicinal plants with antioxidant capabilities to cure or prevent a number of human illnesses in which oxidative stress appears to be a contributing factor has been demonstrated. A growing body of research links free radicals to the etiology of many diseases, supporting the use of antioxidants as a promising therapeutic strategy for the management of pathologies caused by free radicals. Despite these remarkable advances, there is still much to learn about the relationship between free radicals and antioxidants. Understanding the principles behind pathological and physiological disorders caused by free radicals is crucial. Importance of Oxidative Stress and Antioxidant System in Health and Disease contributes to understanding the fundamental principles of oxidative stress and the effects of antioxidants on disease and health.
    Keywords: reactive oxygen species ; antioxidants ; cardiovascular disease ; phytochemicals ; drug resistance ; infertility ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Vitamin E in Health and Disease (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Vitamin E is a group of fat-soluble compounds found in a wide variety of foods. Daily requirements of vitamin E can be met with a balanced diet. High-dose supplementation may be hazardous rather than beneficial. Vitamin E serves as an antioxidant, participates in anti-inflammatory processes, inhibits platelet aggregation, and enhances immunity. Vitamin E supplementation can be beneficial against coronary artery disease, eye disorders, cognitive decline, cancer, and skin aging. This book will mainly focus on the diverse functions of vitamin E, importance of vitamin E status to provide a healthy lifespan, and the interaction between vitamin E and several pathological conditions. Readers will receive a general overview of the importance of vitamin E in health and different pathological conditions.
    Keywords: oxidative stress, antioxidants, pregnancy, nutrition, medicinal plants, reactive oxygen species ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Analytical Liquid Chromatography (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book consists of several selected chapters on important subjects in modern high-performance liquid chromatography (HPLC) and ultra-performance liquid chromatography (UPLC). The content addresses aspects related to both improvements in the mainstream HPLC/UPLC technology and utilization, as well as developments of exploratory new materials and equipment. The book presents useful details about the presented subjects as well as describes new applications and/or relevant case studies for each subject. It is addressed to a large audience of analytical chemists involved in separation science. Each chapter is authored by scientists with considerable field and academic experience.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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    Soybean (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Soybean is an agricultural crop of tremendous economic importance. Soybean and food items derived from it form dietary components of numerous people, especially those living in the Orient. The health benefits of soybean have attracted the attention of nutritionists as well as common people.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Vitamin B and Vitamin E (2024)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Vitamin B is a water-soluble vitamin that plays important roles in cell metabolism and synthesis of red blood cells. Many foods contain B vitamins, including meat, poultry, and fish, among others. Vitamin E is a fat-soluble vitamin with antioxidant properties that can be found in vegetable oils, cereals, meat, poultry, eggs, and fruits. Both vitamins B and E are important for human health. This book provides a comprehensive overview of vitamins B and E. It is organized into three sections on the role of vitamin B on body health and gut flora, vitamin B deficiency and its association with the disease pellagra, and the medicinal significance and complications associated with vitamin E deficiency.
    Keywords: thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Recent Advances in Chemical Kinetics (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Recent Advances in Chemical Kinetics provides a comprehensive overview of several types of chemical reactions. It includes six chapters that discuss solvent catalysis, customized flow reactors, p-conjugation in kinetics, kinetics of autoxidation, molecular chameleon for cations and anions, and internal clocks of atoms.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
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    Pluripotent Stem Cells (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Protein Interactions (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Protein interactions, which include interactions between proteins and other biomolecules, are essential to all aspects of biological processes, such as cell growth, differentiation, and apoptosis. Therefore, investigation and modulation of protein interactions are of significance as it not only reveals the mechanism governing cellular activity, but also leads to potential agents for the treatment of various diseases. The objective of this book is to highlight some of the latest approaches in the study of protein interactions, including modulation of protein interactions, development of analytical techniques, etc. Collectively they demonstrate the importance and the possibility for the further investigation and modulation of protein interactions as technology is evolving.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Biochemistry (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Over the recent years, biochemistry has become responsible for explaining living processes such that many scientists in the life sciences from agronomy to medicine are engaged in biochemical research. This book contains an overview focusing on the research area of proteins, enzymes, cellular mechanisms and chemical compounds used in relevant approaches. The book deals with basic issues and some of the recent developments in biochemistry. Particular emphasis is devoted to both theoretical and experimental aspect of modern biochemistry. The primary target audience for the book includes students, researchers, biologists, chemists, chemical engineers and professionals who are interested in biochemistry, molecular biology and associated areas. The book is written by international scientists with expertise in protein biochemistry, enzymology, molecular biology and genetics many of which are active in biochemical and biomedical research. We hope that the book will enhance the knowledge of scientists in the complexities of some biochemical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of biochemistry.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Polymerase Chain Reaction (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book is intended to present current concepts in molecular biology with the emphasis on the application to animal, plant and human pathology, in various aspects such as etiology, diagnosis, prognosis, treatment and prevention of diseases as well as the use of these methodologies in understanding the pathophysiology of various diseases that affect living beings.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Soybean (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Soybean is an agricultural crop of tremendous economic importance. Soybean and food items derived from it form dietary components of numerous people, especially those living in the Orient. The health benefits of soybean have attracted the attention of nutritionists as well as common people.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Quantitative Structure-activity Relationship (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The book, which is related to QSAR in sciences, is divided into five main chapters. The first chapter is the Introductory chapter. The second chapter aims to provide an update of the recent advances in the field of rational design of PDE inhibitors. The third chapter includes designing a series of peptidic inhibitors that possessed a substrate transition-state analog and evaluating the structure-activity relationship of the designed inhibitors, based on docking and scoring, using the docking simulation software Molecular Operating Environment. The aim of the forth chapter is to develop structure-property relationships for the qualitative and quantitative prediction of the reverse-phase liquid chromatographic retention times of chlorogenic acids. The final chapter aims to determine the model of interactions between the natural compounds with anti-inflammatory molecular target by molecular docking analysis.
    Keywords: alzheimer’s disease, molecular dynamics, anti-inflammatory, fractal dimension, natural compounds, coffee ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Superfood and Functional Food (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Superfoods and functional foods are receiving increasing attention because of their important roles in health. This book focuses on the production of superfoods and functional foods and their role as medicine. In the early chapters, prominent researchers introduce the roles and production of microalgae and functional fruits through metabolic engineering, the use of food waste, and effective cooking procedures. In the latter chapters, other prominent researchers introduce the medical effects of polyphenols, glutamine, and unsaturated fatty acids, which are contained in superfoods and functional foods. They suggest the importance of superfoods and functional foods in the treatment and prevention of many diseases. It is also recommended for readers to take a look at a related book, Superfood and Functional Food: An Overview of Their Processing and Utilization.
    Keywords: cancer, bioactive compounds, microalgae, biotechnology, cardiovascular diseases, functional foods ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    A Critical Evaluation of Vitamin D (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Vitamin D, a fat-soluble vitamin, also called as "sunshine vitamin" is derived mostly from sun exposure and food, and for normal activation, it has to undergo two hydroxylation reactions. Vitamin D affects more than 2000 genes in the body. Serum level of 25(OH) D is an ideal indicator of vitamin D status in our body. Vitamin D deficiency leads to various diseases. On a therapeutic point of view, vitamin D helps to treat many diseases. The book "A Critical Evaluation of Vitamin D - Clinical Overview" targets the principles, mechanisms, and clinical significance of vitamin D. This book covers four sections: "Vitamin D in Cardiovascular and Renal Diseases", "Vitamin D in Age and Neurological Diseases", "Vitamin D and Cancer" and "Therapeutic Measurements of Vitamin D". Each of these sections is interwoven with the theoretical aspects and experimental techniques of basic and clinical sciences. This book will be a significant source to students, scientists, physicians, healthcare professionals and also other members of this society who are interested in exploring the role of vitamin D in human life. [Vitamin D can be considered as vitamin of "defense" since it cures several diseases. - Sivakumar Gowder]
    Keywords: chronic kidney disease, vitamin d deficiency, breast cancer, nanoparticles, alzheimer’s disease, cardiovascular disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Frontiers and New Trends in the Science of Fermented Food and Beverages (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: From time immemorial fermented foods have undoubtedly contributed to the progress of modern societies. Historically, ferments have been present in virtually all human cultures worldwide, and nowadays natives from many ancient cultures still conduct a wide variety of food fermentations using deep-rooted recipes and processes. Within the last four centuries, scientific research has started to unravel many aspects of the biological process behind fermentations, which has contributed to the improvement of many industrial processes. During our journey in the research field, we have always been attracted to the development of scientific research around fermentations, especially autochthonous ferments: a natural repository of novel biomolecules and biological processes that will positively impact on many application fields from health, to food, to materials.
    Keywords: nutrition, fermentation, fluorescence, probiotics, antioxidant activity, phenolic compounds ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Proteomics (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research.
    Keywords: Proteins ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Kinetics of Enzymatic Synthesis (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Kinetics of Enzymatic Synthesis gives insight into different aspects of chemical reactions that are catalyzed by enzymes. This book is divided into two sections: "Enzyme Kinetics" and "Enzymatic Synthesis". The first section consists of two chapters with a halophilic enzyme kinetics and thermodynamic approach towards analyzing the influence of co-solvents on the Michaelis constants of enzyme-catalyzed reactions. The second section consists of three chapters. Production of isoamyl acetate using the enzymatic synthesis method between acetic anhydride and isoamyl alcohol by having enzyme Candida antarctica Lipase B as catalyst in a solvent-free system is discussed in the third chapter. The integrated scheme with the use of the filtrate from the pretreatment of the CS and the growth conditions of Pleurotus cystidiosus is studied in the fourth chapter. The last chapter of this section provides the conditions of the key parameters in microfluidic systems (residence times, flow rates, concentrations) applied for a sequential process from liquid/liquid extraction of LVV-h7.
    Keywords: cellulose, lignin, biorefinery, thermodynamics, bioactive peptides, microfluidic ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Polymerase Chain Reaction for Biomedical Applications (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Do you want to know the details that should be taken into consideration in order to have accurate conventional and real-time PCR results? If so, this book is for you. Polymerase Chain Reaction for Biomedical Applications is a collection of chapters for both novice and experienced scientists and technologists aiming to address obtaining an optimized real-time PCR result, simultaneous processing of a large number of samples and assays, performing PCR and RT-PCR on cell lysate without extraction of DNA or RNA, detecting false-positive PCR results, detecting organisms in viral and microbial diseases and hospital environment, following safety assessments of food products, and using PCR for introduction of mutations. This is a must-have book for any PCR laboratory.
    Keywords: gene expression, pcr, microrna, food safety, microorganisms, dna ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Vitamin K2 (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book serves as a comprehensive survey of the impact of vitamin K2 on cellular functions and organ systems, indicating that vitamin K2 plays an important role in the differentiation/preservation of various cell phenotypes and as a stimulator and/or mediator of interorgan cross talk. Vitamin K2 binds to the transcription factor SXR/PXR, thus acting like a hormone (very much in the same manner as vitamin A and vitamin D). Therefore, vitamin K2 affects a multitude of organ systems, and it is reckoned to be one positive factor in bringing about "longevity" to the human body, e.g., supporting the functions/health of different organ systems, as well as correcting the functioning or even "curing" ailments striking several organs in our body. Vitamin K2 - Vital for Health and Wellbeing has been produced and distributed through the support from Kappa Bioscience, Norway.
    Keywords: nf-κb, drug delivery, bacteria, hepatocellular carcinoma, cardiovascular, osteoporosis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Cell Growth (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book on cell growth is the ideal resource for a scientist who wishes to learn more about cell growth topics. It provides information on plant growth hormones, kinetic studies on cell growth, growth of fungal cells and production, cell growth measurement, ion homeostasis response to nutrient deficiency stress in plants, intracellular lipid homeostasis in eukaryotes, and cell-based assays in cancer research. Each topic begins with a summary of the essential facts. Chapters were carefully edited to maintain consistent use of terminology and approach of covering topics in a uniform, systematic format.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Protein Phosphorylation (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Protein phosphorylation reactions are carried out in a cell by protein kinases, which predominantly use ATP as a phosphate donor that is transferred and covalently bound to an amino acid on a substrate protein. Protein phosphorylation was discovered in 1954 by Edmond Fischer who shared the Nobel Prize in Medicine or Physiology in 1992 with Edwin Krebs. There are so many kinases that one was called "Just Another Kinase" for JAK kinase. Their counterpart is protein phosphatases that remove phosphates from phosphorylated proteins. Kinases and phosphatases act as switches in the cell that activates or inactivates protein functions. These reactions are reversible; the cell can quickly react to a situation but can then go back to its initial state.
    Keywords: cancer, biomarker, biosensor, aggregation, spinal cord injury, neurotoxicity ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Phytochemicals (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.
    Keywords: flavonoids, cancer, oxidative stress, medicinal plants, bioactive compounds, essential oils ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Rice Improvement (2021)
    Springer Nature | Springer
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    Publication Date: 2024-04-14
    Description: This book is open access under a CC BY 4.0 license. By 2050, human population is expected to reach 9.7 billion. The demand for increased food production needs to be met from ever reducing resources of land, water and other environmental constraints. Rice remains the staple food source for a majority of the global populations, but especially in Asia where ninety percent of rice is grown and consumed. Climate change continues to impose abiotic and biotic stresses that curtail rice quality and yields. Researchers have been challenged to provide innovative solutions to maintain, or even increase, rice production. Amongst them, the ‘green super rice’ breeding strategy has been successful for leading the development and release of multiple abiotic and biotic stress tolerant rice varieties. Recent advances in plant molecular biology and biotechnologies have led to the identification of stress responsive genes and signaling pathways, which open up new paradigms to augment rice productivity. Accordingly, transcription factors, protein kinases and enzymes for generating protective metabolites and proteins all contribute to an intricate network of events that guard and maintain cellular integrity. In addition, various quantitative trait loci associated with elevated stress tolerance have been cloned, resulting in the detection of novel genes for biotic and abiotic stress resistance. Mechanistic understanding of the genetic basis of traits, such as N and P use, is allowing rice researchers to engineer nutrient-efficient rice varieties, which would result in higher yields with lower inputs. Likewise, the research in micronutrients biosynthesis opens doors to genetic engineering of metabolic pathways to enhance micronutrients production. With third generation sequencing techniques on the horizon, exciting progress can be expected to vastly improve molecular markers for gene-trait associations forecast with increasing accuracy. This book emphasizes on the areas of rice science that attempt to overcome the foremost limitations in rice production. Our intention is to highlight research advances in the fields of physiology, molecular breeding and genetics, with a special focus on increasing productivity, improving biotic and abiotic stress tolerance and nutritional quality of rice. ; Up-to-date contributions by experts from international research centers and universities Provides practical knowledge and strong scientific foundation on rice biotechnology All-in-one resource for current advances in rice breeding Open Access
    Keywords: Agriculture ; Plant Breeding/Biotechnology ; Plant Genetics and Genomics ; Plant Physiology ; Nutrition ; Plant Biotechnology ; Plant Genetics ; Open Access ; Rice Biotechnologies ; Rice Breeding ; biotic stress tolerance ; abiotic stress tolerance ; Submergence tolerance ; Biofortification ; Marker Assisted and Forward Breeding ; disease resistance ; CRISPR/CAS ; Agricultural science ; Botany & plant sciences ; Biotechnology ; Genetics (non-medical) ; Biochemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TV Agriculture and farming::TVB Agricultural science ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Lipoproteins (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: In mammalian blood plasma there exist some 6 major lipoprotein classes. Under physiological conditions lipoproteins are certainly beneficial as they transport nutrients and steroids to numerous organs for further metabolism. On the other hand, under pathophysiological conditions most lipoprotein classes promote atherogenesis except of HDL that are considered to be anti-atherogenic. Lipoprotein research is a wide field comprising basic science, analytical methods and clinical investigations. Thus this issue does not raise the claim to give a comprehensive picture of the current knowledge, but rather focuses on specific questions related to animal models in lipoprotein research as well as features of the most atherogenic lipoprotein, Lp(a).
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Reactive Oxygen Species (2022)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The term “reactive oxygen species” (ROS) refers to a group of reactive molecules and free radicals produced by molecular oxygen. In recent decades, there has been great interest in the role of ROS in various diseases. From basic science research to clinical trials, biomedical scientists have made rapid progress toward a better understanding of ROS-metabolizing systems and their role in health and diseases. This book includes sixteen chapters that address topics such as the history of ROS, its role in autoimmunity, neurodegeneration, and aging, and recent advances in various antioxidants and their therapeutic potential.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Affinity Chromatography (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Most will agree that one major achievement in the bio-separation techniques is affinity chromatography. This coined terminology covers a myriad of separation approaches that relies mainly on reversible adsorption of biomolecules through biospecific interactions on the ligand. Within this book, the authors tried to deliver for you simplified fundamentals of affinity chromatography together with exemplarily applications of this versatile technique. We have always been endeavor to keep the contents of the book crisp and easily comprehensive, hoping that this book will receive an overwhelming interest, deliver benefits and valuable information to the readers.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Redox Chemistry (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Redox reactions are involved in biochemistry, energy, corrosion, and much more. In both biology and electrochemistry, the redox reaction is complex and varied. For example, redox shuttles in supercapacitors show aspects of molecular electrochemistry applied to electrode porosity. In pseudocapacitors, the formalism associated with their electrochemical response requires investigation and formalism. Similarly, the simple definition of redox potential opens fundamental questions about its measurement in solutions without supporting salts. This book illustrates the variety of redox reactions in its examination of the importance of redox molecules in the development of new electrical energy storage devices.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRH Electrochemistry and magnetochemistry
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    Vitamin C (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Vitamin C, or ascorbic acid, is mainly present in fruits and vegetables. The consumption of such foods is important since the human body does not have the ability to produce this essential micronutrient. Because it is water soluble, it can also easily be lost in cooking and long-term storage. Even though the role of vitamin C has been known since the early 1930s, only recently have researchers been actively studying and demonstrating its role and function in the treatment and prevention of many diseases. These studies will be the key to providing the scientific basis that explains why this simple but important vitamin possesses such a wide range of positive biological activities.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Free Radical Medicine and Biology (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Although free radicals perform some useful immune functions, they can also damage healthy cells through a process called oxidation. Antioxidants reduce the effect of free radicals by binding together with these harmful molecules, decreasing their destructive power. This book highlights various issues of free radical biology from the perspective of antioxidant defense mechanisms. It also provides useful information on gene modulation, radiation-generated reactive oxygen species-induced apoptosis in cancer, and environmental aspects associated with free radicals’ exposure on living systems.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Achieving Zero Hunger in India (2023)
    Springer Nature | Springer Nature Singapore
    Details
    Publication Date: 2024-04-14
    Description: This open access volume discloses rich set of findings and policy recommendations for India towards achieving the SDG 2.1 target of zero hunger by 2030. Through its fourteen chapters, it takes an integrated approach by examining diverse aspects of food and nutrition security through multidisciplinary lens of Agricultural Economics, Nutrition, Crop Sciences, Anthropology and Law, while being rooted in economics. The chapters reflect this diversity in disciplines in terms of the questions posed, the data sets used, and the methodologies followed. Starting from the evolution of policy response for hunger and nutrition security, the book covers aspects such gender budgeting, dietary diversity, women’s empowerment, calorie intake norms, socio-legal aspects of right to health, subjective wellbeing, bio-fortification, crop insurance and food security linkages, interdependence of public distribution system (for food security) and employment guarantee schemes especially during COVID-19 pandemic, effects of dairy dietary supplements, and so on. With its rich discussions, the book is compelling for students, researchers, policy makers, development professionals and practitioners working in areas of food and nutrition security, SDGs, in particular SDG1, SDG2 and SDG5, and sustainable food systems.
    Keywords: Sustainable Development Goals ; Food Security ; SDG2, SDG1, SDG5 ; Hunger ; Nutrition ; Dietary Diversity ; Undernutrition ; India ; Women and children nutrition ; Dietary supplements ; Food wellbeing ; Food and health ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TV Agriculture and farming::TVB Agricultural science ; thema EDItEUR::J Society and Social Sciences ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering::TDCT Food and beverage technology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Generation of Aromas and Flavours (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Consumer product acceptance and market success are dependent on the product's aroma/flavour. Flavours can be produced through chemical synthesis, microbial biocatalysis or by extraction from plants and animal sources. In recent times, chemical synthesis is not as desirable as this is not eco-friendly. So, in the food industry, natural ingredients are added to preparations for efficiency, softness or emotional appeal. Microbiology, bioengineering and biochemistry have enabled the elucidation of metabolic pathways; genetic engineering is expected to help in identifying metabolic blockages and creating novel high-yielding strains, while proteomics help in the application of analytical techniques. All these sciences, old and new, will lead to innovative ideas in the quest for better, sustainable and consumer-approved flavours and aromas.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Homology Molecular Modeling (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Homology modeling is an extremely useful and versatile technique that is gaining more and more space and demand in research in computational and theoretical biology. This book, “Homology Molecular Modeling - Perspectives and Applications”, brings together unpublished chapters on this technique. In this book, 7 chapters are intimately related to the theme of molecular modeling, carefully selected and edited for academic and scientific readers. It is an indispensable read for anyone interested in the areas of bioinformatics and computational biology. Divided into 4 sections, the reader will have a didactic and comprehensive view of the theme, with updated and relevant concepts on the subject. This book was organized from researchers to researchers with the aim of spreading the fascinating area of molecular modeling by homology.
    Keywords: Proteins ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    New Advances in Stem Cell Transplantation (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book documents the increased number of stem cell-related research, clinical applications, and views for the future. The book covers a wide range of issues in cell-based therapy and regenerative medicine, and includes clinical and preclinical chapters from the respected authors involved with stem cell studies and research from around the world. It complements and extends the basics of stem cell physiology, hematopoietic stem cells, issues related to clinical problems, tissue typing, cryopreservation, dendritic cells, mesenchymal cells, neuroscience, endovascular cells and other tissues. In addition, tissue engineering that employs novel methods with stem cells is explored. Clearly, the continued use of biomedical engineering will depend heavily on stem cells, and this book is well positioned to provide comprehensive coverage of these developments.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Solubility of Polysaccharides (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Sugars, with a scientific term as saccharides, are involved in various aspects in the lives of human beings, including the sense of taste, energy for daily life, etc. Recent development in polysaccharides, as well as the background knowledge in this field, further deepens insight into their roles as healthy supplements. In this book, the principles on polysaccharides' solubility and structure, methodologies and application of polysaccharides have been reviewed. The chapters in this book include the relationship between structure and solubility of polysaccharide, the experimental and computational researches on polysaccharide solubility and the common polysaccharide, which may further aid scholars and researchers in regard to solubility of polysaccharides, methodologies and modification.
    Keywords: chitosan, antioxidant activity, chitin, rheology, hydrolysis, osmotic pressure ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Phase Equilibria With Supercritical Carbon Dioxide (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: We are living in a critical time, both for humanity and the planet, which has led us to look for more sustainable formulas to interact with the environment. One of the important changes in the design and operation of chemical processes is the search for environmentally friendly technologies. Supercritical carbon dioxide has been revealed as a promising environmentally friendly solvent that is energy efficient, selective and capable of reducing waste, making it a promising alternative to conventional organic solvents. However, reliable and versatile mathematical models of phase equilibrium thermodynamics are needed for the use of supercritical carbon dioxide in process design and viability studies. This book reviews experimental procedures for obtaining high-pressure phase equilibria data and describes the phase diagrams of binary mixtures and some thermodynamic models capable of determining the conditions of phase equilibria at high pressures. These concepts are applied to the components of the transesterification reaction of rac-2-pentanol with a vinyl ester, which is important in the pharmaceutical industry because (S)-2-pentanol can be obtained as a reaction product. This product is a key intermediate in the synthesis of drugs against Alzheimer’s disease.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
    Language: English
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    Molecular Medicine (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Molecular medicine is an applied science focused on human genes/transcripts, proteins, metabolites, and metabolic networks that describes molecular and cellular processes of health and disease onset and progression. Molecular medicine-based integrative identification and characterization of biomarker targets and their clinical translations is essential to explain/decipher the mechanism(s) underlying physiological pathways and pathological conditions, and acquire cell-targeted early interventional and therapeutic strategies in the context of precision medicine and public health. Principally, Molecular Medicine provides an overview of the latest headlines/developments of systems and molecular medicine, highlighting the emerging high-throughput technologies, promising potential applications, and progress in biomedical research and development strategies.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Plant Physiological Aspects of Phenolic Compounds (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Phenolic compounds are considered secondary metabolites within the physiology of a plant. They have different functions, such as pollination systems, sun protection, protection against pathogens and diseases, etc.Research on these compounds has increased due to the number of molecules they can include and the different biological activities they demonstrate. It is important to know the methods of extracting molecules, the biosynthesis routes, and their relationship with activities that can benefit from their consumption. Therefore, the book includes chapters that provide information on extraction and optimization techniques, biosynthetic pathways, and the identification and characterization of miRNAs involved in the regulation of their biosynthesis.
    Keywords: polyphenols, oxidative stress, antioxidant, nutrition, bioactive compounds, metabolism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Fatty Acids (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: The purpose of this book is to concentrate on recent developments on fatty acids. The articles collected in this book are contributions by invited researchers with a long-standing experience in different research areas. We hope that the material presented here is understandable to a broad audience, not only scientists but also people with general background in many different biological sciences. This volume offers you up-to-date, expert reviews of the fast-moving field of fatty acids. The book is divided into four major sections: (1) Fatty Acids in Physiopathology, (2) Fatty Acids and Cancer, (3) Fatty Acids in Aquatic Organisms, and (4) Fatty Acids in Veterinary and Dairy Products.
    Keywords: cancer, microalgae, inflammation, pregnancy, nutrition, cardiovascular disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Pectins (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book deepens the study and knowledge on pectins, especially in the processes of extraction, purification, and characterization, in short its many and wide applications. Among the most prominent applications are the food, pharmaceutical, and other industries. The development of pectins has a very promising future with a marked annual increase and with a wide range of sources. As written above, this book will help its readers to expand their knowledge on this biopolymer with vast application in the industry worldwide.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Grain and Seed Proteins Functionality (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Climate resilience and growing population are the two main global challenges that encourage the development of an affordable and sustainable source of vegetable protein to ensure future food security. Advanced scientific programs and agro-food developments should be proprietarily on-demand to face different stresses in order to maintain yield and quality of seed production. In this regard, legume crops are key sustainable alternatives for healthier diets while contributing to appropriate natural resource management. Taken together, the 11 chapters in this book represent a generous addition to the progress in our understanding of climate-resilient legumes, hoping to contribute to the improvement of global food security in the future.
    Keywords: nutraceuticals, functional properties, bioactive peptides, essential amino acids, cancer, diabetes mellitus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Essential Oils (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Essential oils have been used for centuries by communities all over the world in various areas and for various purposes. These include uses in medicine, flavoring, perfumery, cosmetics, insecticides, fungicides, and bactericides, among others. They are natural and biodegradable substances, generally nontoxic or with low toxicity to humans and other animals. Therefore, constant research in these areas represents an alternative for new and more efficient drugs with less side effects as well as obtaining new products and supplies. This book provides a comprehensive overview of the diverse applications of essential oils in a variety of human activities with a focus on the most important evidence-based developments in the various fields of knowledge.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Advances in Protein Kinases (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Proteins are the work horses of the cell. As regulators of protein function, protein kinases are involved in the control of cellular functions via intricate signalling pathways, allowing for fine tuning of physiological functions. This book is a collaborative effort, with contribution from experts in their respective fields, reflecting the spirit of collaboration - across disciplines and borders - that exists in modern science. Here, we review the existing literature and, on occasions, provide novel data on the function of protein kinases in various systems. We also discuss the implications of these findings in the context of disease, treatment, and drug development.
    Keywords: Enzymology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    New Trends in Ion Exchange Studies (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book covers new systems in technology that have developed our knowledge of ion exchange. This book discusses ion exchange resins to enhance cell growth; anion exchange membrane; nanosystems in ion exchange and ion exchange in environmental applications. The ion exchange system is used in bionanotechnology, cosmetic industry and water treatment.
    Keywords: chitosan, drug delivery, biomarker, water, nanotechnology, polymer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Applications of Immunocytochemistry (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Immunocytochemistry is classically defined as a procedure to detect antigens in cellular contexts using antibodies. However, over the years many aspects of this procedure have evolved within a plethora of experimental setups. There are different ways to prepare a given specimen, different kinds of antibodies to apply, different techniques for imaging, and different methods of analyzing the data. In this book, various ways of performing each individual step of immunocytochemistry in different cellular contexts are exemplified and discussed. Applications of Immunocytochemistry offers technical and background information on different steps of immunocytochemistry and presents the application of this technique and its adaptations in cell lines, neural tissue, pancreatic tissue, sputum cells, sperm cells, preimplantation embryo, arabidopsis, fish gonads, and Leishmania.
    Keywords: Biochemical immunology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Covalent Organic Frameworks (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: In recent decades, artificial porous structures have attracted increasing enthusiasm from researchers inspired by the fascinating molecular pores in nature and their unique biological functions. Although substantial achievements in porous materials have been realized, the construction of topologically designed pores is still challenging. Recently, the emergence of covalent organic frameworks (COFs), which are constructed based on organic and polymer chemistry, has made it possible to design artificial pores with controlled pore size, topology and interface properties. COFs are crystalline porous materials constructed by the precise reticulation of organic building blocks via dynamic covalent bonds. Distinct from non-covalent interactions which tend to produce isostructures, covalent bonds enable accurate pore design owing to their predetermined reaction pathways. In addition, the appropriate polycondensation of organic building units enables the formation of extended two-dimensional (2D) and three-dimensional (3D) polymer architectures with periodically ordered skeletons and well-defined pores. With their large surface area, tailorable structures, and tunable chemistry, COFs are regarded as potentially superior candidates for various applications including catalysis, energy storage and conversion, mass transport and biotechnology. This book examines the historic achievement of COFs, providing clear and comprehensive guidance for researchers on their structural design, synthetic protocols and functional exploration.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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    Fluoride (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Fluoride covers a continuum of topics that are frequently studied in the broad area of fluoride (F) research. It provides an overview of the primary sources of environmental fluoride in typical high-fluoride environments and demonstrates the transitions and transformations that emerge and culminate in hydro-geochemical interactions that result in fluoride-fouling of large portions of the world’s water and agricultural resources. This way, the book pinpoints the connection between F enrichment of water sources and the prevalence of endemic fluorosis in certain areas of the world. In order to contribute to a better understanding of the global fluoride problem, new fluoride detection and quantification technologies are proposed with an in-depth analysis of emerging trends in the use of portable user-friendly devices in point-of-use measurements of water fluoride. This has been presented against the backdrop of a robust overview of traditional fluoride quantification methodologies that are still in wide application among the scientific communities. In addressing fluoride toxicities, which are not limited to dental and skeletal dilapidations, the authors have explored the role of natural antioxidants in ameliorating physiological fluoride-induced noxious effects in mammalian systems. Nonetheless, since community dependence on high-fluoride water due to a lack of alternative clean water sources remains to be the principal pathway of human fluoride over-exposure, a review chapter on F mitigation techniques applied all over the world is incorporated aiming at providing a succinct overview of water defluoridation techniques and strategies being used to combat the impacts of human F overexposure around the globe. Since every cloud has a silvery lining, the possibility of using ammonium fluorides as a novel reagent in mineral processing has been considered convenient industrial fluorinating agents, which present the possibility of complete regeneration that is not afforded by the reagents presently used in decomposing silicon component of the ores.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
    Language: English
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    Proteomic Applications in Biology (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The past decade has seen the field of proteomics expand from a highly technical endeavor to a widely utilized technique. The objective of this book is to highlight the ways in which proteomics is currently being employed to address issues in the biological sciences. Although there have been significant advances in techniques involving the utilization of proteomics in biology, fundamental approaches involving basic sample visualization and protein identification still represent the principle techniques used by the vast majority of researchers to solve problems in biology. The work presented in this book extends from overviews of proteomics in specific biological subject areas to novel studies that have employed a proteomics-based approach. Collectively they demonstrate the power of established and developing proteomic techniques to characterize complex biological systems.
    Keywords: Proteins ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Recent Trends for Enhancing the Diversity and Quality of Soybean Products (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book presents new aspects and technologies for the applicability of soybean and soybean products in industry (human food, livestock feed, oil and biodiesel production, textile, medicine) as well as for future uses of some soybean sub-products. The contributions are organized in two sections considering soybean in aspects of food, nutrition and health and modern processing technologies. Each of the sections covers a wide range of topics. The authors are from many countries all over the world and this clearly shows that the soybean research and applications are of global significance.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Exploring Chemistry with Pyridine Derivatives (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book discusses the chemistry and applications of pyridine derivatives. The library of pyridine derivatives is growing steadily with numerous synthetic analogues already described and the identification of new, naturally occurring pyridine-based compounds. The book includes ten chapters organized into two parts. The first part focuses on the numerous types of reactions that arise from pyridine derivatives. The second part examines the pharmaceutical applications of pyridine derivatives as well as their usefulness as sensors for metal cations and extracting agents for platinum group metals.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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    Dosimetry (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The book discusses multiple issues associated with modern dosimetry in physics and treatment planning and how investigators from diverse world centers and institutions approach problem-solving in these important areas. It examines topics including pretreatment validation and factors affecting reference dosimetry. It also addresses unique issues affecting pediatric populations as well as the modern role of thermoluminescence validation. Several chapters discuss intensity modulation, including defining modern problems associated with both treatment planning and the definition of tumor and normal tissue contours. Furthermore, the book examines the role of imaging as both a vehicle to define tumor targets and normal tissue as well as a tool for dose validation.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRL Nuclear chemistry, photochemistry and radiation
    Language: English
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    Nucleic Acids (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This edited book, "Nucleic Acids - From Basic Aspects to Laboratory Tools", contains a series of chapters that highlight the development and status of the various aspects of the nucleic acids related to DNA chemistry and biology and the molecular application of these small DNA molecules and related synthetic analogues within biological systems. Furthermore, it is hoped that the information in the present book will be of value to those directly engaged in the handling and use of nucleic acids, and that this book will continue to meet the expectations and needs of all who are interested in the different fascinating aspects of molecular biology.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Peripheral Membrane Proteins (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The peripheral membrane proteins transduce the extracellular signaling into the cells. The peripheral membrane proteins include the G protein-coupled receptors, receptor tyrosine kinases, channels and transporters. The signals, which are transduced via the peripheral membrane proteins, activate several pathways including G protein signaling, MAPK signaling, TNF signaling, TGF? signaling, Wnt signaling and Hedgehog signaling. The peripheral membrane proteins transduce the signaling from the extracellular ligands into the cells. This book intends to provide a comprehensive overview of the features and signaling of peripheral membrane proteins, which includes the molecular structure and interaction. The insights into membrane proteins associated with diseases and therapeutics and the effects of drugs and chemicals are also discussed in this book.
    Keywords: innate immunity, prostate cancer, yeast, signal transduction, crystallization, morphogenesis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Non-Proteinogenic Amino Acids (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The first description of homocysteine (Hcy), a non-proteinogenic amino acid, was introduced in a case study more than 70 years ago. In recent years, numerous studies have shown a positive correlation between serum levels and various diseases, especially vascular pathology. Vitamins B6, B12, and folic acid play a major role in controlling homocysteine levels. In this book are presented both methods for the determination of homocysteine and its involvement in human pathology. Homocysteine levels can be taken as an early indicator for the detection of cardiovascular diseases because Hcy levels increase after a myocardial infarction or stroke.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Biomineralization (2021)
    Springer Nature
    Details
    Publication Date: 2024-04-01
    Description: This open access book is the proceedings of the 14th International Symposium on Biomineralization (BIOMIN XIV) held in 2017 at Tsukuba. Over the past 45 years, biomineralization research has unveiled details of the characteristics of the nano-structure of various biominerals; the formation mechanism of this nano-structure, including the initial stage of crystallization; and the function of organic matrices in biominerals, and this knowledge has been applied to dental, medical, pharmaceutical, materials, agricultural and environmental sciences and paleontology. As such, biomineralization is an important interdisciplinary research area, and further advances are expected in both fundamental and applied research.
    Keywords: Life sciences ; Biochemistry ; Mineralogy ; Inorganic chemistry ; Cell biology ; Biomaterials ; Dentistry ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKE Dentistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNV Chemistry of minerals, crystals and gems ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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    Methods in Molecular Medicine (2021)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Treatment risk and response to therapy prediction can be forecasted through early diagnosis, which improves prognosis reliability and effectiveness of therapies. This book covers contemporary advances in molecular markers, disease-causing variants, retroelements, and the basis of distinct diseases.
    Keywords: Molecular biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Some New Aspects of Colloidal Systems in Foods (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Some New Aspects of Colloidal Systems in Foods is a new book on food emulsions, which provides in-depth coverage of some new aspects of food colloids. The coverage includes confident overviews of theoretical issues as well as descriptions of new techniques and recent colloid research findings. Specific topics include the role of electrostatic and steric forces in the stabilization of food colloids, antioxidants in food emulsions, nanoemulsions, and nanostructured colloids in food science. This book can be used as a specialized text for graduate students and researchers in food science and technology. In addition, it will serve as a reference text for advanced students in chemistry, engineers, biochemists, nutritionists, and analytical chemists in the food industry and research.
    Keywords: oxidative stress, antioxidants, safety, food industry, nanoemulsions ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Progress in Carotenoid Research (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: The book "Progress in Carotenoid Research" presents an authoritative and comprehensive overview of the biology, biochemistry, and chemistry of carotenoids. Divided into 14 discrete parts, this book covers topics on basic science and applied technology of carotenoid molecules. This book provides an insight into future developments in each field and has an extensive bibliography. It will be an essential resource for researchers and academic and industry professionals in the natural pigment field.
    Keywords: carotenoids, astaxanthin, lycopene, remote sensing, mass spectrometry, fermentation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Secondary Metabolites (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book provides an overview of secondary metabolites in three sections: “Introduction”, “Secondary Metabolites: General Reviews and Biotechnological Interventions” and “Plant Secondary Metabolites.” It discusses the antimicrobial, anticancer, and antioxidant activities of secondary metabolites, biotechnological interventions in the production and research of secondary metabolites, and the secondary metabolites of plants.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Update on Mesenchymal and Induced Pluripotent Stem Cells (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book represents an updated overview on selected topics related to mesenchymal stem cells as well as induced pluripotent stem cells. The book is divided into three main sections that cover several topics including: sources of both stem cell types, their preparation and general properties, as well as their therapeutic indications and clinical utilization with particular attention given to their use in infectious diseases, osteoarthritis, as well as immunological disorders.
    Keywords: Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Flavonoid Metabolism (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: The presence of flavonoids such as chalcones, flavones, flavonols, anthocyanins, and proanthocyanidins is ubiquitous throughout the plant kingdom. It was previously believed that the oldest plants that produced flavonoids were liverworts and mosses. However, recent discoveries have found genes encoding enzymes in the shikimate pathway responsible for flavonoid biosynthesis in a variety of plants including algae, liverworts, mosses, lycophytes, ferns and horsetails, gymnosperms, and angiosperms. These genes include the first two enzymes for flavonoid biosynthesis, chalcone synthase and chalcone isomerase. Furthermore, recent research has found flavones, isoflavones, and flavonols in microalgae from five distinct evolutionary lineages(Cyanobacteria, Rhodophyta, Chlorophyta, Haptophyta, and Ochrophyta) using ultra-high performance liquid chromatography with tandem mass spectrometry. This implies that plants may have developed the capacity to make flavonoids earlier than previously believed. Flavonoids in the earliest plants that produced them were believed to have acted as protection against UV radiation and control of plant hormone activity. As plants evolved, these roles diversified, and the study of flavonoids has revealed how plants developed the capacity to produce a wide array of specialized metabolites and then evolved the metabolic pathways required to manufacture them. This book delves into the structural diversity of flavonoids found throughout the plant kingdom, the evolution of flavonoid biosynthesis genes in plants, and the molecular interaction of flavonoids with growth hormones. The metabolic routes of flavonoids are thoroughly investigated using both biochemical and molecular biology methods, and the book elucidates the links between genes/proteins and metabolites, as well as between metabolites. The book also explores the interplay between flavonoid metabolism and external environmental factors that are subject to continuous change.
    Keywords: flavonoids ; biosynthesis ; agriculture ; bioactive compounds ; secondary metabolites ; genetic engineering ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Soybean (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book presents the importance of applying of novel genetics and breading technologies. The efficient genotype selections and gene transformations provide for generation of new and improved soybean cultivars, resistant to disease and environmental stresses. The book introduces also a few recent modern techniques and technologies for detection of plant stress and characterization of biomaterials as well as for processing of soybean food and oil products.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Ubiquitin Proteasome System (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: The human ubiquitin proteasome system (UPS) is comprised of nearly 1000 proteins. Although originally identified as a mechanism of protein destruction, the UPS has numerous additional functions and mediates central signaling events in myriad processes involved in both cellular and organismal health and homeostasis. Numerous pathways within the UPS are implicated in disease, ranging from cancer to neurodegenerative diseases such as Parkinson's. The goal of this book is to deliver a collection of synopses of current areas of UPS research that highlights the importance of understanding the biology of the UPS to identify disease-relevant pathways, and the need to elucidate the molecular machinations within the UPS to develop methods for therapeutic modulation of these pathways.
    Keywords: cancer, ubiquitination, autophagy, immune system, dna damage, cell cycle ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Protein Detection (2022)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: The book explores distinct aspects of protein purification and characterization steps. It discusses solubility problems, resin selection tricks, and essential credentials in a purification process. In addition, the book examines aggregation and proteinopathy-related protein detection methods and reviews several essential protein detection and characterization methods in cancer for diagnosis, prognosis, and therapy, such as enzyme-linked immunosorbent assay (ELISA), immunohistochemistry, flow cytometry, western blot, mass spectrometry, and others.
    Keywords: Proteins ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Chemical Properties of Starch (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book is about the chemical properties of starch. The book is a rich compendium driven by the desire to address the unmet needs of biomedical scientists to respond adequately to the controversy on the chemical properties and attendant reactivity of starch. It is a collective endeavor by a group of editors and authors with a wealth of experience and expertise on starch to aggregate the influence of qualitative and quantitative morphological, chemical, and genetic properties of starch on its functionalities, use, applications, and health benefits. The chemical properties of starch are conferred by the presence, amount and/or quality of amylose and amylopectin molecules, granule structure, and the nature and amounts of the lipid and protein molecules. The implication of this is comprehensively dealt with in this book.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Desalination (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: The book comprises 14 chapters covering all the issues related to water desalination. These chapters emphasize the relationship between problems encountered with the use of feed water, the processes developed to address them, the operation of the required plants and solutions actually implemented. This compendium will assist designers, engineers and investigators to select the process and plant configuration that are most appropriate for the particular feed water to be used, for the geographic region considered, as well as for the characteristics required of the treated water produced. This survey offers a comprehensive, hierarchical and logical assessment of the entire desalination industry. It starts with the worldwide scarcity of water and energy, continues with the thermal - and membrane-based processes and, finally, presents the design and operation of large and small desalination plants. As such, it covers all the scientific, technological and economical aspects of this critical industry, not disregarding its environmental and social points of view. One of InTech's books has received widespread praise across a number of key publications. Desalination, Trends and Technologies (Ed. Schorr, M. 2011) has been reviewed in Corrosion Engineering, Science & Technology – the official magazine for the Institute of Materials, Minerals & Mining, and Taylor & Francis's Desalination Publications. Praised for its “multi-faceted content [which] contributes to enrich it,” and described as “an essential companion...[that] enables the reader to gain a deeper understanding of the desalination industry,” this book is testament to the quality improvements we have been striving towards over the last twelve months.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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    B Group Vitamins (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: B-group vitamins are involved in numerous metabolic reactions and their widespread deficiency can cause a large series of health problems. The aim of this book is to provide an update on the current use and perspectives of B-group vitamins. Novel methods to detect folates in pregnant women, the use and role of folate dentistry, the use of genotype notification to modify food intake behavior, thiamin metabolism in Archaea and its role in plants and in crop improvement, the use of riboflavin in blood safety and niacin in metabolic stress and resistance in dairy cows are some of the subjects that are described in this multitopic book written by authors from seven different countries.
    Keywords: folate, oxidative stress, stress, insulin, dentistry, polymorphism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Protein-Protein Interactions (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Proteins are indispensable players in virtually all biological events. The functions of proteins are coordinated through intricate regulatory networks of transient protein-protein interactions (PPIs). To predict and/or study PPIs, a wide variety of techniques have been developed over the last several decades. Many in vitro and in vivo assays have been implemented to explore the mechanism of these ubiquitous interactions. However, despite significant advances in these experimental approaches, many limitations exist such as false-positives/false-negatives, difficulty in obtaining crystal structures of proteins, challenges in the detection of transient PPI, among others. To overcome these limitations, many computational approaches have been developed which are becoming increasingly widely used to facilitate the investigation of PPIs. This book has gathered an ensemble of experts in the field, in 22 chapters, which have been broadly categorized into Computational Approaches, Experimental Approaches, and Others.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Iron Metabolism (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Iron is an essential element for numerous fundamental biologic processes. Iron-containing proteins are required for vital cellular and organismal functions including oxygen transport, mitochondrial respiration, intermediary and xenobiotic metabolism, nucleic acid replication and repair, host defense, and cell signaling. However, excess iron is toxic. This book provides a comprehensive overview of the essential role of iron in biology, the regulation of systemic and cellular iron homeostasis, and how imbalances in iron homeostasis contribute to disease.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    The Wheat Genome (2024)
    Springer Nature | Springer International Publishing
    Details
    Publication Date: 2024-04-05
    Description: This open access book provides the first comprehensive coverage of the wheat genome sequence since the publication of the draft and reference sequences for bread wheat and durum wheat. It presents an overview and all aspects of the gold standard sequence of the bread wheat genome, IWGSC RefSeq v1.0 and its subsequent improvements through 2022 (IWGSC RefSeq v2.1), as well as the sequencing of multiple elite wheat varieties, durum wheat, and ancient wheat. The book provides a broad and extensive review of the resources, tools, and methodologies available for exploiting the wheat genome sequence for crop improvement and studying fundamental questions related to the structure, function, and evolution of the wheat genome. Wheat (Tritcum aestivum L.) is the most widely grown crop in the world, contributing approximately 20 percent of total calories and more protein in human diets than any other single source. This book is useful to students, teachers, and scientists in academia and industry interested in gaining an understanding of the wheat genome and its application as well as plant scientists generally interested in polyploid plant species.
    Keywords: International Wheat Genome Sequencing Consortium ; polyploidy ; wheat genome sequence ; structural genomics ; functional genomics ; wheat evolution ; wheat improvement ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TV Agriculture and farming::TVB Agricultural science ; thema EDItEUR::U Computing and Information Technology::UY Computer science ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Cellular Metabolism and Related Disorders (2021)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: This book deals with a vital topic: metabolism in the cells of the body and various disorders due to its imbalance and/or diseases that disrupt the metabolism of the body. The objective of this book was to collect and compile up-to-date information from reputed researchers in their respective fields to disseminate the latest information about topics that have profound effects on the metabolic processes in the body including insulin resistance, diabetes mellitus, hypothyroidism, metabolic syndrome, glycogen storage disease, and the urea cycle disorder. In total, there are 12 chapters in this book in which the authors have shared their research findings and real-life experiences in managing their patients.
    Keywords: Biochemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Trace Elements and Their Effects on Human Health and Diseases (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book is an excellent compilation of trace elements and their positive and negative effects on human health and the environment. Over two sections, the book examines the adverse effects of trace elements in the human body and the atmosphere and how to overcome them.
    Keywords: oxidative stress, breast cancer, antioxidant, public health, genotoxicity, environmental hazards ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Advanced Gas Chromatography (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Progress in agricultural, biomedical and industrial applications' is a compilation of recent advances and developments in gas chromatography and its applications. The chapters cover various aspects of applications ranging from basic biological, biomedical applications to industrial applications. Book chapters analyze new developments in chromatographic columns, microextraction techniques, derivatisation techniques and pyrolysis techniques. The book also includes several aspects of basic chromatography techniques and is suitable for both young and advanced chromatographers. It includes some new developments in chromatography such as multidimensional chromatography, inverse chromatography and some discussions on two-dimensional chromatography. The topics covered include analysis of volatiles, toxicants, indoor air, petroleum hydrocarbons, organometallic compounds and natural products. The chapters were written by experts from various fields and clearly assisted by simple diagrams and tables. This book is highly recommended for chemists as well as non-chemists working in gas chromatography.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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