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  • Rat  (826)
  • Fracture
  • La Sassa cave (Central Italy)
  • Springer  (891)
  • Institute of Physics
  • Public Library of Science
  • 1
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    La Sassa cave: Isotopic evidence for Copper Age and Bronze Age population dynamics in Central Italy (2023)
    Public Library of Science
    Details
    Publikationsdatum: 2023-08-29
    Beschreibung: This study focuses on the changes in diet and mobility of people buried in the La Sassa cave (Latium, Central Italy) during the Copper and Bronze Ages to contribute to the understanding of the complex contemporary population dynamics in Central Italy. To that purpose, carbon and nitrogen stable isotope analyses, strontium isotope analyses, and FT-IR evaluations were performed on human and faunal remains from this cave. The stable isotope analyses evidence a slight shift in diet between Copper and Bronze Age individuals, which becomes prominent in an individual, dating from a late phase, when the cave was mainly used as a cultic shelter. This diachronic study documents an increased dietary variability due to the introduction of novel resources in these protohistoric societies, possibly related to the southward spread of northern human groups into Central Italy. This contact between different cultures is also testified by the pottery typology found in the cave. The latter shows an increase in cultural intermingling starting during the beginning of the middle Bronze Age. The local mobility during this phase likely involved multiple communities scattered throughout an area of a few kilometers around the cave, which used the latter as a burial site both in the Copper and Bronze ages.
    Beschreibung: Published
    Beschreibung: e0288637
    Beschreibung: 6A. Geochimica per l'ambiente e geologia medica
    Beschreibung: 6SR VULCANI – Servizi e ricerca per la società
    Beschreibung: 7SR AMBIENTE – Servizi e ricerca per la società
    Beschreibung: JCR Journal
    Schlagwort(e): La Sassa cave (Central Italy) ; population dynamics ; nitrogen isotope ; strontium isotope
    Repository-Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Materialart: article
    Standort Signatur Erwartet Verfügbarkeit
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    ARTIKEL (OA)
  • 2
    Digitale Medien
    Digitale Medien
    Postprandial thermogenesis of rats with glutamate induced obesity in relation to energy intake (1993)
    Springer
    European journal of nutrition 32 (1993), S. 71-73 
    Details
    ISSN: 1436-6215
    Schlagwort(e): Rat ; glutamate-induced obesity ; postprandial thermogenesis ; Ratte ; Glutamat-induzierte Adipositas ; postprandiale Thermogenese
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft , Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Bei 4 Monate alten Ratten mit Glutamat-induzierter Adipositas wurde die postprandiale Thermogenese über 8 h nach Fütterung von 300, 450 und 600 kJ/kg0,75 einer Pellet-Diät mittels indirekter Kalorimetrie in computergesteuerten Stoffwechselkäfigen mit offenem Kreislauf bestimmt. Bei den adipösen Tieren war die postprandiale Thermogenese nach Aufnahme von 600 kJ/kg0,75 (oberhalb des Energieerhaltungsbedarfs) signifikant auf 40% der Thermogenese der Kontrolltiere reduziert (12,0 gegenüber 31,5 kJ/kg0,75×8 h). Es wird geschlußfolgert, daß die Ratte mit Glutamat-induzierter Adipositas als ein Tiermodell mit beeinträchtigter fakultativer Thermogenese anzusehen ist, die hauptsächlich durch eine Verminderung der sympathischen adrenergen Aktivität verursacht ist.
    Notizen: Summary Postprandial thermogenesis was estimated in 4-month-old male rats with glutamate induced obesity after being fed with 300, 450 and 600 kJ/kg0.75 of a pellet diet, respectively by indirect calorimetry in computer-controlled open circuit metabolic cages over 8 h. After an intake of 600 kJ/kg0.75 (above the maintenance energy requirement) postprandial thermogenesis was significantly reduced in the obese animals to about 40% of control rats (12.0 versus 31.5 kJ/kg0.75×8 h). It is concluded that the glutamate obese rat can be accepted as an animal model with impaired facultative thermogenesis, mainly caused by a reduction of sympathetic adrenergic activity.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01610087
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Identification of brain tumours in rats using laser-induced fluorescence and haematoporphyrin derivative (1989)
    Springer
    Lasers in medical science 4 (1989), S. 241-249 
    Details
    ISSN: 1435-604X
    Schlagwort(e): Brain tumour ; Rat ; Detection ; Fluorescence ; Laser ; Haematoporphyrin derivative
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Physik , Technik allgemein
    Notizen: Abstract Laser-induced fluorescence has been used for the identification of brain tumours in rats, which have been previously given tumour-seeking haematoporphyrin derivative. A pulsed nitrogen laser (λ=337 nm) was used in conjunction with an optical multichannel analyzer. For both inoculated RG-2 and TCVC rat-brain-tumour models, the blue autofluorescence was strongly reduced in the tumour compared with normal brain tissue, and at the same time the characteristic red-drug signal increased. The contrast between tumour and normal tissue was strongly enhanced by forming the ratio between the two signals. Implications for possible improvement of tumour delineation in brain tumour surgery are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02032454
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Corticotropin releasing factor increases the adrenocortical responsiveness to adrenocorticotropin (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 1004-1006 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Rat ; adrenocortical responsiveness ; ACTH ; plasma ; corticosterone ; plasma ; corticotropin releasing factor (CRF)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary In the course of studying the plasma adrenocorticotropic hormone (ACTH) and corticosterone responses to synthetic corticotropin releasing factor (CRF), we noted some disparity in the responses. A higher dose (20 μg compared with 5 μg per rat i.a.) produced an equal plasma ACTH but greater plasma corticosterone response in adult male rats. Thus, we examined the possibility that CRF increases adrenocortical responsiveness to ACTH. CRF significantly (p〈0.0005) increased the plasma corticosterone response to ACTH in rats pretreated with dexamethasone. Thus, synthetic CRF increases corticosterone secretion in rats not only by stimulating ACTH secretion, but also by increasing the adrenocortical responsiveness to ACTH.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01946481
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  • 5
    Digitale Medien
    Digitale Medien
    Influence of hydrochlorothiazide on the pain threshold and on the antinociceptive activity of morphine, in rats (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 265-266 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Rat ; hydrochlorothiazide ; pain threshold ; antinociceptive activity ; analgesic activity ; morphine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Hydrochlorothiazide, acutely injected in rats, has a weak analgesic activity per se and potentiates and prolongs the antinociceptive effect of morphine.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02002628
    Standort Signatur Erwartet Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 6
    Digitale Medien
    Digitale Medien
    Effect of L-carnitine and stimulated lipolysis on muscle substrates in the exercising rat (1990)
    Springer
    Cellular and molecular life sciences 46 (1990), S. 457-458 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Rat ; carnitine ; lipolysis ; exercise ; glycogen ; triglycerides ; muscle
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary To test the effect of L-carnitine on glycogen sparing when fat oxidation is increased, 100 mg/kg/d were given to rats orally for 3 days, resulting in 1.8-fold higher muscle carnitine levels. Even when FFA were raised by heparin-stimulated lipolysis, the rate of glycogen degradation was not reduced during exercise.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01954228
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Do prostaglandins mediate the somatostatin preventive effect on gastric lesion? (1984)
    Springer
    Cellular and molecular life sciences 40 (1984), S. 974-975 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Rat ; prostaglandins ; gastric lesion ; intragastric distension model ; stress model ; indomethacin ; somatostatin preventive effect
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The inhibition of endogenous prostaglandin synthesis by indomethacin treatment blocks the somatostatin preventive effect on the gastric lesions induced in a stress model and has no preventive effect on an intragastric distension model.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01946466
    Standort Signatur Erwartet Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 8
    Digitale Medien
    Digitale Medien
    A two-stage model of fracture of rocks (1996)
    Springer
    Pure and applied geophysics 146 (1996), S. 253-263 
    Details
    ISSN: 1420-9136
    Schlagwort(e): Fracture ; fault nucleation ; critical crack density ; hierarchic failure ; earthquakes ; thermal activation
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie , Physik
    Notizen: Abstract In this paper we propose a two-stage model of rock fracture. In the first stage, cracks or local regions of failure are uncorrelated and occur randomly throughout the rock in response to loading of pre-existing flaws. As damage accumulates in the rock, there is a gradual increase in the probability that large clusters of closely spaced cracks or local failure sites will develop. Based on statistical arguments, a critical density of damage will occur where clusters of flaws become large enough to lead to larger-scale failure of the rock (stage two). While crack interaction and cooperative failure is expected to occur within clusters of closely spaced cracks, the initial development of clusters is predicted based on the random variation in pre-existing flaw populations. Thus the onset of the unstable second stage in the model can be computed from the generation of random, uncorrelated damage. The proposed model incorporates notions of the kinetic (and therefore time-dependent) nature of the strength of solids as well as the discrete hierarchic structure of rocks and the flaw populations that lead to damage accumulation. The advantage offered by this model is that its salient features are valid for fracture processes occurring over a wide range of scales including earthquake processes. A notion of the rank of fracture (fracture size) is introduced, and criteria are presented for both fracture nucleation and the transition of the failure process from one scale to another.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00876492
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Rate of normal longitudinal bone growth in the rat (1972)
    Springer
    Calcified tissue international 10 (1972), S. 238-251 
    Details
    ISSN: 1432-0827
    Schlagwort(e): Growth ; Bone ; Rat ; Tetracycline
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin , Physik
    Beschreibung / Inhaltsverzeichnis: Résumé La vitesse de croissance normale en longueur de la métaphyse proximale du tibia est déterminée chez le rat Sprague-Dawley entre les âges de 20 et 100 jours, en utilisant la méthode à la tétracycline. Le taux de croissance ne varie que légèrement dans les groupes d'âges différents. Il est plus élevé chez les animaux jeunes et décroit considérablement en fonction de l'augmentation de l'âge. Les rats mâles présentent une croissance plus élevée que les femelles. Cette étude a pour but de mettre au point une méthode permettant de déterminer les facteurs expérimentaux, liés à la croissance en longueur du rat.
    Kurzfassung: Zusammenfassung Die normale Längenwachstums-Geschwindigkeit der proximalen Wachstumsplatte der Tibia wurde bei Sprague-Dawley-Ratten in einem Alter zwischen 20 und 100 Tagen mittels der Tetracyclinmethode gemessen. Die Wachstumsgeschwindigkeit variierte nur wenig innerhalb der einzelnen Altersgruppen. Die Geschwindigkeit war bei jungen Tieren am höchsten und nahm mit zunehmendem Alter beträchtlich ab. Männliche Ratten wuchsen schneller als weibliche. Diese Arbeit dient als Grundlage, um die experimentelle Beeinflussung des Längenwachstums der Ratte abschätzen zu können.
    Notizen: Abstract The rate of normal growth in length from the proximal growth plate of the tibia in the Sprague-Dawley rat was measured between 20 and 100 days of age using the tetracycline method. The growth rate varied only slightly within different age groups. The rate was highest in young animals and decreased considerably with increasing age. Male rats grew faster than female. This study is intended to provide a base for an evaluation of experimental influence on the growth in length of the rat.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02012553
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Digitale Medien
    Digitale Medien
    Effect of local application of fluoride on healing of experimental bone fractures in rabbits (1977)
    Springer
    Calcified tissue international 22 (1977), S. 297-302 
    Details
    ISSN: 1432-0827
    Schlagwort(e): Fluoride ; Gelfoam ; Fracture ; Ossification ; Breaking force
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin , Physik
    Notizen: Abstract The effect of local application of low fluoride concentrations on the healing of experimental bone-radii fractures in 20 rabbits was examined. No external fixation was required after the osteotomy and gelfoamℜ being used as a medium for fluoride application. Histologic mineral and mechanical strength measurements were carried out on the healing callus. There were no significant changes in the ashpercentage and the fluoride concentration of the ash between the experimental and control callus. A significantly higher percentage of ossified tissue was found in the fluoride treated callus. The breaking strength was found to be significantly higher in the bone fractures treated with fluoride, whereas there was no notable difference between the surface areas. It is postulated that the greater amount of ossified tissues, the differences in organization of the bone trabecules, and/or an improved mineral crystallinity may be responsible for this result.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02010368
    Standort Signatur Erwartet Verfügbarkeit
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