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  • Articles  (736)
  • Chemistry  (734)
  • Lipids
  • 1980-1984  (736)
  • Medicine  (736)
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  • Articles  (736)
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  • 1
    Electronic Resource
    Electronic Resource
    Lipid composition of two types of chondrocytes in primary culture (1981)
    Springer
    Calcified tissue international 33 (1981), S. 403-407 
    Details
    ISSN: 1432-0827
    Keywords: Chondrocytes ; Articular cartilage ; Epiphyseal cartilage ; Primary culture ; Lipids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Chondrocytes from articular and growth plate cartilage were grown in primary culture. The lipid content, distribution into different types, as well as the fatty acid patterns of these lipids were compared when the cells had reached stationary phase and were synthesizing maximal amounts of proteoglycans. Numerous significant differences were observed, depending on the origin of the chondrocytes. In particular, growth plate chondrocytes showed increased dry weight, increased lipid content (phosphatides and triglycerides), and decreased cholesterol to phosphatide ratio when compared to articular chondrocytes; they also incorporated more of C18:1 and less C16:0 into their major lipid types. Whether these differences arise from specific metabolic regulation or are a consequence of chondrocyte organization in primary culture remains unclear.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02409463
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  • 2
    Electronic Resource
    Electronic Resource
    Partial purification and characterization of the bone resorption factor fromActinomyces viscosus (1982)
    Springer
    Calcified tissue international 34 (1982), S. 49-53 
    Details
    ISSN: 1432-0827
    Keywords: Bacterial amphophile ; Purification ; Chemistry ; Resorption ; Ca influx ; Cyclic AMP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary The bone resorptive factor and amphipathic antigen (AcA) previously identified by us in preparations fromActinomyces viscosus have been partially purified, characterized chemically, and compared. They elute at the same location on chromatography with Ac 22. The fatty acid composition of AcA and the bone resorptive factor is the same. Some differences in carbohydrate composition are observed. TheActinomyces factor does not affect calcium influx or cyclic AMP in isolated bone cells. Therefore it is concluded that AcA stimulates resorption either by gaining entrance into bone cells or by way of a yet undetermined second messenger.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02411208
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  • 3
    Electronic Resource
    Electronic Resource
    Lipid storage in cultured articular chondrocytes due to prostanoid precursors and a prostanoid synthesis inhibitor (1982)
    Springer
    Cell & tissue research 224 (1982), S. 441-448 
    Details
    ISSN: 1432-0878
    Keywords: Chondrocyte culture ; Prostanoid precursors ; Indomethacin ; Lipids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Lapine articular chondrocytes were subcultured in the presence or absence of the prostanoid precursors, arachidonic acid or dihomo-gammalinolenic acid, and the cyclooxygenase inhibitor indomethacin. Lipid storage was studied microscopically using the Sudan black staining method. Control chondrocyte cultures showed a weakly positive staining reaction until confluence was reached, at which point the intra-cytoplasmic lipid content decreased. Both arachidonic acid and dihomo-gamma-linolenic acid at 100 μmol/l caused a marked increase in lipid storage which continued even after confluence was achieved. 1 μmol/l concentrations were indistinguishable from controls, whereas 10 μmol/l concentrations elicited a slight increase in lipid storage compared with controls. The prostaglandin cyclooxygenase inhibitor indomethacin did not affect chondrocyte lipid storage. However, administration of a prostanoid precursor in the presence of indomethacin caused a massive increase in intra-cytoplasmic storage of lipid, eventually leading to cell death. A possible explanation is that indomethacin may alter chondrocyte lipid metabolism in the presence of substrate molecules by rechanneling lipid synthesis away from the prostaglandin pathway to other lipid synthetic pathways.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00216885
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  • 4
    Electronic Resource
    Electronic Resource
    Performance analysis of total hip prostheses: Some particular metallurgical observations (1980)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 14 (1980), S. 31-40 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Metallurgical observations of phenomena which influence the clinically successful performance of permanent implants and implant materials are reported. The effect of casting voids in cast cobalt chromium femoral stems of total hip replacements is discussed first. Pitting corrosion occurred in a retrieved stainless-steel implant type AISI 316 containing 2.7% Mo. The fractographic pattern of this device retrieved for fatigue failure shows typical characteristics of corrosion-enhanced fatigue.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820140105
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  • 5
    Electronic Resource
    Electronic Resource
    Surface ultrastructure and pressure dynamics of tracheal tube cuffs (1980)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 14 (1980), S. 11-21 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The outer and inner surfaces of six commercial endotracheal tube cuffs were characterized using scanning electron microscopy (SEM) and energy dispersive x-ray analysis. Lateral tracheal wall pressure (LWP) was measured at various steps of cuff inflation using a mock-trachea system. The surface characteristics of the cuffs were found to vary widely. The surface of the Lanz cuff was relatively smooth but showed a regular array of circular depressions 0.8 μm in diameter. Uniform spheres also 0.8 μm in diameter were distributed through the thickness of the membrane. The American Hi-Lo cuff surface was also relatively smooth but was covered widely with flakes of material which x-ray showed to be a clay-like substance containing aluminum, silica, and potassium. The Harlake cuff was covered widely with roughly spherical, 5-μm-diam particles, probably starch granules. The membrane itself was smooth even at 3,000X. The Foregger cuff had a rough surface and was covered with the same clay-like particles seen on the American cuff. The inner surface with irregular, uneven areas were surrounded by fissures. The Rusch Armored tube cuff was completely covered by a continuous 2-μm-thick chlorinated coating. The surface was highly convoluted and irregular. The three cuff membranes showing relatively smooth surfaces, Lanz, American and Harlake, also produced relatively low LWP at various points of cuff inflation. While we have no data to indicate that cuff surface smoothness correlates with tracheal morbidity, it would seem prudent to select cuffs that produce low LWP's with smooth surfaces for clinical use.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820140103
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  • 6
    Electronic Resource
    Electronic Resource
    Masthead (1980)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 14 (1980) 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820140101
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  • 7
    Electronic Resource
    Electronic Resource
    Compositional dependence of the formation of calcium phosphate films on bioglass (1980)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 14 (1980), S. 55-64 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Bioglass, which has a composition of sodium carbonate, calcium carbonate, phosphorous pentoxide and silica, has been shown to bond to living bone. This ability is dependent on controlled surface reactions. Investigators with 45S5 bioglass have demonstrated that the formation of a SiO2-rich layer and a calcium phosphate film on its surface in an aqueous environment is associated with the film bonding the bioglass to bone. The objects of this research were: 1To study SiO2 dependence on the formation of a silica-rich layer and calcium phosphate films on a bioglass surface in a simulated physiological solution, and2To establish a correlation between in vitro surface reactions and in vivo bonding ability.It was discovered that three types of reactions occur in a simulated physiological solution depending on bioglass composition: 1A calcium phosphate film and SiO2-rich layer form simultaneously and the reaction rate is fast for bioglasses which have a lower content of SiO2 (∼46 mol% SiO2).2A SiO2-rich layer forms first and a calcium phosphate film develops later between the aqueous environment and the SiO2-rich layer for bioglasses whose SiO2 content is between 46-55 mol %.3A calcium phosphate film does not form for glasses whose SiO2 content is more than 60 mol %.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820140107
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  • 8
    Electronic Resource
    Electronic Resource
    In vitro heterogeneous degradation of poly(n-alkyl α-cyanoacrylates) (1980)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 14 (1980), S. 93-106 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Methods by which in vitro heterogeneous phase degradation rates of the poly(n-alkyl α-cyanoacrylates) have been directly obtained are described. The data indicate that the rates of degradation in aqueous buffer solutions depend not only upon pH of the medium and length of the monomer alkyl side chain, but also critically upon polymer particle specific surface, particle size, polymer molecular weight, and molecular weight distribution. A modification of the currently held theory of degradation of these polymers is required, and postulated.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820140202
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  • 9
    Electronic Resource
    Electronic Resource
    Implant-bone interface characteristics of bioglass dental implants (1980)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 14 (1980), S. 23-29 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Three-dimensional finite element analysis (FEA) has been used to determine the implant-bone interface characteristics of bioglass dental implants. The results of the FEA were verified by comparison with the results of mechanical testing performed on animal implant specimens. The results of the study showed that the assumption of a discontinuous change of elastic properties at the bone-implant interface was a poor assumption for the bioglass implants. Interface elastic moduli of 354.0, 155.0, and 47.0 MPa for conditions of 25, 50, and 100% tissue attachment were determined for the bioglass implants.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820140104
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  • 10
    Electronic Resource
    Electronic Resource
    Adsorption of plasma proteins on hydrophobic surfaces. IV. Contact angle studies on implanted polymers (1980)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 14 (1980), S. 1-10 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Contact angle studies have been carried out on plasma protein layers adsorbed on selected polymer surfaces under buffered saline at 37°, in an attempt to demonstrate directly a recent suggestion that the interfacial free energy between such protein layers and surrounding liquid phase should be zero at equilibrium. Although an initial contact angle of 180° was always obtained, the angle decayed slowly to a stationary value which varied for any one drop on each polymer surface. The stationary values could be reasonably correlated with the reversible work of adhesion predicted for each polymer/protein combination, suggesting that protein desorption from the solid surface is a dominant event in the contact angle decay process. It is concluded that the data bear more relevance to the protein layer/polymer interface than to the protein layer/solution interface, and that the contact angle technique is not a suitable technique for studying the latter on biomaterials.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820140102
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