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  • Elsevier  (249,080)
  • Wiley-Blackwell  (52,677)
  • Nature Publishing Group  (18,746)
  • 1985-1989  (320,503)
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Year
  • 101
    Electronic Resource
    Electronic Resource
    Indian council to put technology imports under the microscope (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 97-97 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Bangalore THE Indian government is to set up an autonomous council to tackle technology assessment, forecasting and information. The council, under the aegis of the ministry for science and technology, is to prepare a comprehensive report for the Prime Minister once a year on the state of the ...
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    URL: http://dx.doi.org/10.1038/325097b0
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  • 102
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    Afghanistan Academy of Sciences finally gets under way (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 98-98 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] London AFGHANISTAN'S Academy of Sciences, founded in 1979, after the Sowr (pro-Soviet) revolution, and shortly before Soviet military intervention, is to be transformed into a "centre for organizing scientific research and scientific thinking", according to a decision last month of the Afghan ...
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  • 103
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    Japanese experimental nuclear reactor decommissioned (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 100-100 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Tokyo As Japan's nuclear power industry grows by leaps and bounds, the problem of how to deal with reluctant commercial nuclear reactors looms on the horizon. The dismantling of Japan's first experimental nuclear power reactor began last month. The JPDR boiling-water reactor at the Atomic Energy ...
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  • 104
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    India's liberalized software policy (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 101-101 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Bangalore INDIA has developed a new policy on the development of computer software aimed at capturing a larger share of the booming global market. The strategy will allow drastic reduction of import duty, single clearance of applications from software exporters and liberal foreign exchange for ...
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  • 105
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    Polypetide mediator network (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 330-331 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE list of polypeptides regulating the growth, differentiation and function of cells involved in immunity, inflammation and haematopoiesis has grown rapidly during the past decade. Cloning of these factors provided formal evidence for their existence and distinction from other factors, and the ...
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    URL: http://dx.doi.org/10.1038/326330a0
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  • 106
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    Iridium anomalous no longer? (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 331-332 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IT HAS been suggested1 that the process of mass extinction of species is extraterrestrial in origin, probably caused by the impact of large meteorites or comets (bolides) on the Earth. The main evidence for bolide impact is enrichment of the clay at the Cretaceous-Tertiary boundary, a time of great ...
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  • 107
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    Eukaryotes with no mitochondria (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 332-333 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IT is a widespread fallacy that mitochondria are found in all eukaryote cells, and that the symbiotic theory of the origin of mitochondria from purple photosynthetic bacteria, for which the evidence is now exceedingly good, explains the origin of the eukaryote cell itself. In fact it is not ...
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  • 108
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    Antibody–antigen flexibility (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 334-335 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] OUR view of the structural basis of antibody-antigen recognition and the role of flexibility in this process seems to evolve in oscillations whose amplitudes are asymptotically damped by the growing amount of reliable structural data. From Pauling's idea1 of a very flexible and pluri-potent ...
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  • 109
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    Polymers from the Soviet Union (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 335-335 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE possibility of constructing a ferromagnetic array of spins on radicals in an organic material has been known for some time12. Small polyradical molecules have been found that do show strong ferromagnetic exchange coupling between the electron spins within the molecule3. It has not until now ...
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  • 110
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    Trophic factor theory matures (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 336-336 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE Nobel prize in Physiology and Medicine was awarded last September to Stanley Cohen and Rita Levi-Montalcini, recognizing the importance of their work, begun in the 1950s, on the identification and purification of nerve growth factor (NGF), a protein essential for the survival of several ...
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  • 111
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    Nomenclature of immunological markers (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 337-337 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Your editorial policy1 concerning the nomenclature of markers of human leukocyte differentiation antigens is welcome, but does not go far enough. A more extensive list has been official nomenclature of the International Union of Immunological Societies and the World Health Organisation since ...
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  • 112
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    Can a negative quantity be deemed a probability? (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 338-338 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-One could say that it is reasonable to use the idea of negative probabilities1"1 if a body of results valid for normal (that is, positive) probabilities is changed in an elegant or informative way when some of the probabilities involved are given negative values. It is for this sort of reason ...
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  • 113
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    Presentation of the past (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 339-339 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IT is odd to find a psychologist, however courageous, attempting to write a general history of the subject, especially a work that spans "the dawn of civilization to the present day". Not only is there now so much - too much, perhaps - to be included, but the task itself can hardly be approached ...
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  • 114
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    Glycine-binding sites and NMDA receptors in brain (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 338-338 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-I was fascinated by the report by Johnson and Ascher1 in which they describe an interaction between the amino-acid neurotransmitters glycine and glut-amate in cultured mouse neurons. Glycine is generally accepted as an inhibitory transmitter, certainly within the spinal cord, whereas glutamate ...
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  • 115
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    Soliton theory and Jupiter's great red spot (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 337-338 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Antipov et al.1 recently presented some remarkable results from an ingenious laboratory analogue of the shallow-water equations on a rapidly-rotating /3-plane, in which an apparently isolated, stable anticyclonic eddy formed spontaneously in the presence of a mechanically driven lateral shear ...
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  • 116
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    Tracking back to Africa (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 340-341 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SICKLE cell disease is a common and serious genetic disorder, affecting approximately one in every five hundred newborn black children. Even with good medical care this disease carries a relatively high mortality, but in rural Africa most affected individuals die in infancy. Those patients who do ...
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  • 117
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    Science of helium in technology (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 340-340 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] LIQUID helium is something of an oddity. Its existence as a liquid at all is rather marginal, as shown by the ease with which it can be vaporized by tiny influxes of heat - just one watt is enough to evaporate about a litre of liquid in an hour. For temperatures below 2.17K, it behaves as though it ...
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  • 118
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    On the heart beat (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 341-342 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] OF THE inner organs of beasts and fowls, none has been relished more, by arts and science alike, than the heart. Reputed of old as the seat of emotions, but better known these flays for its vulnerability to the ravages of food and smoke, the interest of modern granting agencies in this simple pump ...
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  • 119
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    The dimensions of art (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 342-342 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THIS is a flirt of a book. Lured along by many handsome illustrations, the reader is led down instructive by-ways in the history of geometry and ornament; but the intellectual thread grows ever more slender, the book turns into a vehicle for displaying the author's own paintings, and there is no ...
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  • 120
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    The sombre view of AIDS (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 343-345 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE nature of the AIDS (acquired immune deficiency syndrome) epidemic is of considerable interest to us all, but so far the underlying epidemiology of the disease is not understood. Consequently, predictions of the incidence of the disease can be reliable only for perhaps one to three years ahead. ...
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  • 121
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    Science meets Islam in the Saudi desert (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 346-346 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Riyadh ONE of the most basic of statistics against which to measure the progress of any country is its population. But if the Saudis know what their population is, as surely they must, they are not saying. Semiofficial suggestions range up to 11 million but the British embassy reckons 5-6 ...
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  • 122
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    Knowledge-based prediction of protein structures and the design of novel molecules (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 347-352 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Prediction of the tertiary structures of proteins may be carried out using a knowledge-based approach. This depends on identification of analogies in secondary structures, motifs, domains or ligand interactions between a protein to be modelled and those of known three-dimensional structures. ...
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  • 123
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    Non-cosmological redshifts of spectral lines (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 363-365 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] To explain why source correlations influence the spectrum of the emitted light consider a very simple example. Suppose that two point sources PJ and P2 have identical spectra SQ(CO) and that measurements on the emitted field are made at some point P. The sources are assumed at rest relative to an ...
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  • 124
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    Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 353-358 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We show that nerve growth factor (NGF) synthesis in developing skin begins with sensory innervation and that sensory neurons do not express NGF receptors until their fibres reach their cutaneous targets. Both cutaneous epithelium and mesenchyme synthesize NGF, the concentration of messenger ...
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  • 125
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    Three-dimensional structure of a complex of antibody with influenza virus neuraminidase (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 358-363 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The structure of a complex between influenza virus neuraminidase and an antibody displays features inconsistent with the inflexible 'lock and key' model of antigen‐antibody binding. The structure of the antigen changes on binding, and that of the antibody may also change; the interaction ...
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  • 126
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    Speculations about the origin of H 3 O + seen in cometary mass spectra (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 366-367 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The recent space missions ICE (International Cometary Explorer) to comet Giacobini-Zinner, and Giotto, Sakigake, Suisei and Vega to comet Halley have yielded data concerning the ion and neutral compositions of the gaseous clouds surrounding these comets. The ICE data indicate the presence of ions ...
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  • 127
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    Monopoles in the rotating superfluid helium-3 A–B interface (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 367-370 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The superfluid phase boundary between 3He-A and 3He-B also serves to provide a unique analogy to the cosmic domain walls1*2 that are believed to have precipitated between regions of the early Universe3 in different vacuum states. Hence the proposed experiments on the superfluid 3He A-B interface ...
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  • 128
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    Icosahedral symmetry versus local icosahedral environments in Al–Mn alloys from NMR (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 372-373 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] No known phase of aluminium and manganese has icosahedra bonded in the way Pauling suggests. However the 4G' phase of Al-Mn, having the A112W structure, was reported2 to exist as a metastable precipitate. In the G phase, the Mn-centred Al icosahedra are arranged on a body-centred cubic (b.c.c.) ...
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  • 129
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    Satellite measurements of sea surface cooling during hurricane Gloria (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 373-375 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Hurricane Gloria (1985) began to form very late in the hurricane season off the Cape Verde Islands1. Gloria moved nearly due westward with the trade winds to about the Leeward Islands, and then turned north-west toward the Sargasso Sea. On 25 September the minimum central pressure fell to 919 mbar, ...
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  • 130
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    Organic polymer ferromagnet (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 370-372 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] An organic ferromagnet was prepared by polymerization of the paramagnetic stable biradical, l,4-bis-(2,2,6,6-tetramethyl-4-oxy-4-piperidyl-l-oxyl)-butadiin, (BIPO)11. The transition metal content was controlled by methods including atomic absorp-tional analysis and laser amplified ...
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  • 131
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    A mechanism for the west-north-west movement of monsoon depressions (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 376-378 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Monsoon depressions are one of the most important synoptic-scale disturbances on the quasi-stationary planetary-scale monsoon trough over the Indian region during the summer monsoon season (June to September). While some depressions form in situ, others can be related to weak pressure waves ...
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  • 132
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    Evidence for transform margin evolution from the Ivory Coast–Ghana continental margin (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 378-381 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The interpretations presented here are based mainly on data collected during a survey run in 1983 off the Ivory Coast and Ghana13. About 3,300km of continuous geophysical profiles (3.5 kHz, magnetism and single channel seismic reflection) were obtained along the Ghanaian continental slope and over ...
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  • 133
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    Lead isotope evidence for the structure of the Rockall dipping-reflector passive margin (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 381-383 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Seismic reflection profiles across the passive continental margin south-west of Rockall Plateau, North-east Atlantic (Fig. 1) have revealed the existence of a group of oceanward-dipping reflectors (Fig. 2), a structure that differs considerably from that found on block-faulted Biscay-type margins1. ...
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  • 134
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    Helium isotope disequilibrium and geochronology of glassy submarine basalts (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 384-386 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] A suite of basaltic glasses from small seamounts near the East Pacific Rise at 10-14° N has been analysed. This seamount field erupts chemically diverse lavas ranging from tholeiite (with mid-ocean-ridge basalt (MORE) chemistry) to alkali basalt (from a source with time-integrated higher Rb/Sr, ...
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    Electroreceptors in the platypus (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 386-387 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Discharges recorded in the infraorbital nerve which supplies the bill could be identified as coming from either mechanorecep-tors or electroreceptors. Electroreceptors could be readily distinguished from mechanoreceptors as the electroreceptors showed measurable responses to electrical stimuli in ...
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    Habitat fragmentation and the stability of predator–prey interactions (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 388-390 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] My experiments were performed on an abandoned cattle ranch overlooking Newport Bay in Bristol County, Rhode Island. To minimize extraneous sources of variation, I selected fields that were effectively monocultures of the goldenrod, Solidago canadensis. The prey species, Uroleucon ...
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    Changes in abundance or structure of the per gene product can alter periodicity of the Drosophila clock (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 390-392 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A number of rhythmic strains were developed from arrhythmic (per0)1 Drosophila by P element-mediated transformation with per+ DNA. All lines received the same JFfmdlll fragment of ~7 kilobases (kb) previously shown to contain DNA coding for the 4.5-kb per transcript2'6. The structure of the ...
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    DNA marker analysis detects multiple maternity and paternity in single broods of the lesser snow goose (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 392-394 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table 1 Genotypes of nest attendants and goslings of four lesser snow goose families DNA marker DQSG1-AI DQSG1-AII DQSG1-CI DQSG5-BI DQSG5-BH DQSG5-BIU DQSG6-AIS DQSG7-BI DQSG7-BII DQSG7-BIII DQSG8-BI DQSG8-BII DQSG8-DI ...
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    Influence of parental chromosomes on spatial specificity in androgenetic ↔ parthenogenetic chimaeras in the mouse (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 395-397 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Androgenetic and parthenogenetic (equivalent to gyno-genetic)9 eggs were prepared as described previously1*8'10. The androgenetic eggs contained the paternal genome of strain CFLP, homozygous for the a allele of the enzyme glucose phosphate isomerase (GPI), Gpi-l& jGpi-l-*9 and the ...
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    Depletion of cytosolic free calcium induced by photosynthesis (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 397-400 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In order to maximize the tip diameter of the Ca2H~-selective electrode, and hence minimize the response time constant, single-barelled electrodes were employed in conjunction with a KCl-filled potential-measuring electrode. Figure 1 shows that in darkness or dim light, intracellular measurements of ...
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    The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3 (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 400-403 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We established an assay of purified CD2 binding to human lymphoid cells. CD2 was solubilized with the detergent Triton X-100 and purified to near homogeneity from the human T lymphoblast line SKW3 by affinity chromatography as described12'13 and labelled with 125I (Fig. la inset). CD2 was shown to ...
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    Somatic hypermutation of an immunoglobulin transgene in K transgenic mice (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 405-409 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We used antigenic selection to increase the likelihood of isolating cells that had undergone somatic mutation in transgenic mice carrying the rearranged K-gene isolated from the myeloma MOPC-16718. The light-chain V region encoded by this gene (VK167) is known to be frequently used in the antibody ...
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    Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 403-405 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Whereas supernatant media collected from bone marrow stromal cell cultures have no detectable HCGF activity, dialysed salt-extracts of the stromal layer itself stimulate colony formation by granulocyte-macrophage colony-forming cells (GM-CFC) in agar cultures (Fig. la and b). This result suggested ...
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    Rearrangement of a chicken immunoglobulin gene occurs in the lymphoid lineage of transgenic mice (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 409-411 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The microinjected DNA fragment (11.5 kilobases (kb)) encodes the chicken immunoglobulin A light-chain locus in its germline configuration7. It contains the VA1,*/A and CA coding exons, 1.4 kb 5' and 4.8 kb 3' of chicken genomic flanking regions (Fig. 1). Approximately 50 copies were microinjected ...
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    Ribosomal RNA sequence suggests microsporidia are extremely ancient eukaryotes (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 411-414 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Although higher taxa of eukaryotes, such as kingdoms and phyla, have been generally defined by macro- and micro-morphological criteria, opinions in the field of protist taxonomy vary widely, making the understanding of evolutionary relationships in this group uncertain (for reviews see refs 9-12). ...
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    High-speed countercurrent chromatography (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 419-420 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Support-free high-speed countercurrent liquid chromatography provides a rich domain of applications, some beyond reach of conventional liquid chromatography. ...
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    Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 414-416 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It had been shown that a top2 ts mutant is capable of undergoing one, and only one, complete round of DNA replication at the non-permissive temperature2. As a topi mutant grows normally, it obviously has no significant defect in DNA replication6'7. In contrast, DNA replication is severely affected ...
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    Structure of a mutant of tyrosyl-tRNA synthetase with enhanced catalytic properties (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 416-418 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The tyrosyl-tRNA synthetase from Bacillus stearothermophilus catalyses the aminoacylation of its tRNA by the following two-step reaction4: E + Tyr+ATP = E o Tyr-AMP + PPi E o Tyr-AMP+tRNAtyr = Tyr-tRNAtyr + AMP + E. The TP51 mutant shows a 15-fold decrease in KM (ATP), which, with a ...
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    FASEB highlights (1987)
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    Nature 326 (1987), S. 420-424 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] This year's conference of the Federation of American Societies of Experimental Biology on 29 March–3 April in Washington, D.C., will feature products of use to every experimental biologist. ...
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    The Vatican and embryology (1987)
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    Nature 326 (1987), S. 229-230 
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    Notes: [Auszug] THE Vatican, represented by the Congregation of the Faith, has done itself more harm than good with its statement last week on the lawful and illicit uses of new techniques in human embryology. While claiming a foundation in modern science, the statement emerges as a restrictive prescription out of ...
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    European research crisis (1987)
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    Nature 326 (1987), S. 230-230 
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    Notes: [Auszug] THERE is something in the view that Europe has been living in a crisis of transition since the time of Charlemagne. Europe's problem is that of reconciling its sense that united action will be beneficial with the wayward determination of its several national states that they should individually say ...
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    British Labour Party science policy (1987)
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    Nature 326 (1987), S. 231-231 
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    Notes: [Auszug] ON Thursday 26 March 1987, Nature will be providing a forum in London at which Labour Party representatives will outline their policy on science. As space is limited, anybody wishing to attend should telephone Neil Crombie in London on 01-836 6633, extension ...
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    Europe underestimates cost of space programme (1987)
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    Nature 326 (1987), S. 231-231 
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    Notes: [Auszug] London THE European Space Agency (ESA) has underestimated by more than £600 million (1,100 million European Currency Units, ECU) the amount needed annually to fund its new space programme, precipitating a major rescheduling of its proposed international research projects. The British ...
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    Protropin status questioned by FDA decision (1987)
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    Nature 326 (1987), S. 231-231 
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    Notes: [Auszug] Washington A DECISION by the US Food and Drug Administration (FDA) may cause the biotechnology company Genentech to lose its position as market leader in sales of recombinant human growth hormone (rhGH). Last week, FDA granted approval to Eli Lilly & Co. to market another version of the ...
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    AIDS becomes a notifiable disease in Japan despite protests (1987)
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    Nature 326 (1987), S. 232-232 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Tokyo JAPAN is about to introduce legislation to make AIDS (acquired immune deficiency syndrome) a notifiable disease. But critics claim that the law will be a grave infringement of human rights. The following are the main provisions of the AIDS bill: doctors must report the age, sex and ...
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    AIDS education programme in Japan (1987)
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    Nature 326 (1987), S. 232-232 
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    Notes: [Auszug] Tokyo JAPAN is taking several steps to combat AIDS (acquired immune deficiency syndrome). The Health and Welfare Ministry has distributed a 100-page booklet on the disease to prefectural governments across the country; the Education Ministry has instructed education boards to initiate AIDS ...
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    New director at BGS (1987)
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    Nature 326 (1987), S. 232-232 
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    Notes: [Auszug] London THE UK Natural Environment Research Council (NERC) has appointed Mr F.G. Larminie to a two-year term as director of the British Geological Survey from September, on the retirement of the present director Mr G. I. ...
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    Tests for AIDS in pregnancy on offer to all (1987)
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    Nature 326 (1987), S. 232-232 
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    Notes: [Auszug] Munich VOLUNTARY testing for AIDS (acquired immune deficiency syndrome) should be available for all pregnant women. That was the conclusion of an international symposium on infectious diseases in gynaecology and obstetrics held at the University of Munich earlier in the month. The ...
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    Cattle farming in the desert heat an unexpected success for Arabs (1987)
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    Nature 326 (1987), S. 233-233 
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    Notes: [Auszug] Riyadh HOLSTEIN cattle, originally bred to suit the temperate climate and green pastures of the Netherlands, would not seem to be the ideal choice for a dairy herd in the scorching Saudi-Arabian desert. But 17,600 Holsteins on a farm 50 miles south of Riyadh, the country's capital, not only ...
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    Nature; 326.1987, 6110, S.233 (1987)
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    Nature 326 (1987), S. 233-233 
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    Notes: [Auszug] THIS colour photograph of the recent supernova (SN 1987a) in the Large Magel-lanic Cloud (LMC) (see p. 239) was taken at the European Southern Observatory in La Silla, Chile on 25 February, two days after the supernova exploded. The super- nova, which had reached a visual magnitude of 4.5 at the ...
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    New science minister (1987)
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    Nature 326 (1987), S. 233-233 
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    Notes: [Auszug] Munich WEST Germany's new minister for education and science, Jiirgen Mollemann, is likely to encourage the development of privately run universities that compete with state-supported higher education. Molleman, 41, has been a paratrooper as well as an elementary school teacher. He is the first ...
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    Turk researchers harassed (1987)
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    Nature 326 (1987), S. 233-233 
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    Notes: [Auszug] London A TURKISH research ship, the Piri Reis, belonging to the Marine Sciences Institute of the "Ninth September" University (Izmir) has become involved in the dispute between Greece and Turkey over drilling rights in the Aegean. The Piri Reis has made a number of geological survey trips both in ...
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    Frank Press re-elected (1987)
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    Nature 326 (1987), S. 233-233 
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    Notes: [Auszug] Washington MEMBERS of the National Academy of Sciences have re-elected Frank Press for a second six-year term as president. Press, 62, first became president in 1981, succeeding the late Philip Handler. He has been a member of the academy since 1968. Earlier, he served as President Carter's ...
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    First success of powder methods (1987)
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    Nature 325 (1987), S. 109-110 
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    Notes: [Auszug] THE first refinement of the structure of a complex zeolite, using synchrotron X-ray powder diffraction, has recently been announced by scientists from the University of California at Santa Barbara, Brookhaven National Laboratory and Union Carbide1. Interest in synthetic zeolites during the past ...
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    Non-verbal thinking by animals? (1987)
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    Nature 325 (1987), S. 110-112 
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    Notes: [Auszug] EINSTEIN once claimed that the distinction between past, present and future is only an illusion (for convinced physicists, at least), but most of us seek to manage our future on the lessons of yesterday. In this, memory plays a key role. Using it we detect, for example, pattern and order relations ...
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    Nature; 325.1987, 6100, S.111 (1987)
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    Nature 325 (1987), S. 111-111 
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    Notes: [Auszug] FOR many years, Eric Kandel and his colleagues at Columbia University have been unravelling the changes in neural activity that accompany the acquisition of learned behaviours in the sea slug Apfysia. On page 153 of this issue, F. Belardetti, E.R. Kandel and S. Siegelbaum report the latest step in ...
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    Politics and wildlife in Australia (1987)
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    Nature 325 (1987), S. 112-112 
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    Notes: [Auszug] IN 1979, 6,144 km2 of the Northern Territories of Australia was proclaimed stage 1 of the Kakadu National Park, and in 1981 the UNESCO World Heritage Committee inscribed it as the first Australian world heritage property. Stage 2 of the park, a further 6,929 km2, was proclaimed in 1984, and the ...
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    Is scrapie Prp 27–30 related to AIDS virus? (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 113-114 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Haseltine and Patarca1 recently reported on regions of local sequence resemblance between the hamster gene for PrP 27-30, a protein associated with scrapie infectivity, and the polymerase (pol) open reading frame of the human immunodeficiency virus, HIV (strain human T-cell lymphotropic virus ...
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    Function of Claws' claws (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 114-114 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Two possible ecological roles have been proposed by Charig and Milner for the new theropod dinosaur Baryonyx1. The skull and skeleton of Baryonyx show several apparent adaptations to feeding on fish (ichthyophagy) including a long, narrow snout with a terminal expansion, numerous finely ...
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    Vagaries of nomenclature and the rigidity of the Code (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 114-114 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Recent criticisms1 4 of the International Code of Zoological Nomenclature are relevant to a remonstrance I received from some of my entomological friends, for having dared to point out the improper (grammatically) spelling of names of several Anopheles species in a book on practical ...
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    Volumes apart (1987)
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    Nature 325 (1987), S. 114-114 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Zimmerberg and Parsegian (Nature 323, 36-39; 1986) have introduced a new method to study the pores of ionic channels. They report large changes in the internal volume of a channel protein - the volume inaccessible to polymers - when the channel opens or closes. The internal volume of a channel ...
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    Volumes apart (1987)
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    Nature 325 (1987), S. 114-114 
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    Notes: [Auszug] PARSEGIAN AND ZIMMERBERG REPLY - We thought the distinction in definition of volumes was obvious in the title and the text. If not, we hope that similarly bemused readers will benefit from Eisenberg's elaboration of this ...
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    The information sensation (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 115-115 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] NOT long ago, a normally balanced and slightly conservative BBC TV science programme interviewed the director of a leading artificial intelligence (AI) laboratory in the United States. The man, comfortably seated, pronounced that: As machines evolve, and machines get smarter and smarter, it ...
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    Technology for the drosophilist (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 116-116 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE attraction of Drosophila to wine is noted in the earliest reference I know to this fly - John Milton's Paradise Regained (1671). Despite more recent advances in science, the molecular basis of the phenomenon is still unknown. Nevertheless, Drosophila is used as a "model" organism for the study ...
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    Neutrinos from the supernova (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 239-239 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE first few weeks of Supernova 1987a have seen a flurry of IAU (International Astronomical Union) telegrams, hastily written preprints and late night telephone calls. Astronomers, already accustomed to dealing with unexpected celestial events, have mobilized with admirable speed. It is even more ...
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    Competition among different taxa (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 241-241 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] As species of the same genus have usually, though by no means invariably, some similarity in habits and constitution, and always in structure, the struggle will generally be more severe between species of the same genus, when they come into competition with each other, than between species of ...
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    Engineering mutant mice (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 240-241 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] LESCH-NYHAN syndrome is a rare, tragic inherited disorder affecting boys'. The major symptoms are spasticity of the limbs, involuntary movements, mental retardation and the bizarre habit of compulsive self-mutilation. It is classic, textbook knowledge that the syndrome is caused by deletions and ...
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    Receptor-operated Ca channels (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 242-242 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THERE is hardly any tissue where receptor-operated calcium channels have not been postulated. Evidence from biochemical and tracer flux studies indicates that they are involved in many diverse cellular functions (see ref. 1 for a review). In contrast, electrophysiologists have had until recently ...
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    New perspectives on the history of ancient Maya civilization (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 242-243 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] OUR understanding of ancient Maya civilization has undergone huge changes in recent years. Although the exciting breakthroughs in deciphering Maya hieroglyphic writing and in appreciating the ideological roles of the Maya elite have justifiably received much publicity1, equally significant ...
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    First observation of a quasar with a redshift of 4 (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 131-133 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] At present, quasars are the only objects that can be found in significant numbers at large redshifts and are useful in a variety of studies related to the early history of the Universe. Individual quasars are interesting in themselves and they may also be used as probes, to study the properties of ...
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    Specific antigen—la activation of transfected human T cells expressing murine Ti αβ —human T3 receptor complexes (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 125-130 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The genes encoding the α and β chains of the T-cell receptor (Ti) of an antigen-specific, Ia-restricted murine T-cell hybridoma were introduced into T3-positive or T3-negative human T cells. The resultant transfectants express either mouse-human or mouse-mouse Ti αβ molecules ...
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    Tidal heating in an internal ocean model of Europa (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 133-134 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Calculations of tidal dissipation in Europa have been only partly successful in accounting for a tidal heating rate large enough to prevent the solidification of an internal ocean. Cassen et al.8 corrected their original work4 and concluded that a subsurface liquid water layer would be rather ...
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    A new clathrate hydrate structure (1987)
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    Nature 325 (1987), S. 135-136 
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    Notes: [Auszug] Clathrate hydrates, ice-like host–guest systems containing guest molecules in cages of hydrogen-bonded water molecules exist in three well-characterized cubic forms, and a less well-characterized tetragonal form1,2. On the basis of 2H and l29Xe NMR ...
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    Phosphate glasses for identification of heavy ions (1987)
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    Nature 325 (1987), S. 137-138 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We define three quantities which characterize the ability of a chemical reagent to reveal the track of an ionizing particle: the general etching rate, i 〉G, is the linear rate of dissolution of the surface of the solid, which depends on the reagent and the temperature; the track etching rate, i ...
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    Shedding of an Agulhas ring observed at sea (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 138-140 
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    Notes: [Auszug] The estimated volume flux of the Agulhas current in its southern reaches exceeds 130 x 106m3 s"1, (ref. 14), making it the major western boundary current of the southern hemisphere. Fig. 1 a, Thermal infrared image from the METEOSATII satellite showing the geographic disposition of elements of the ...
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    Cell fusion in viral diseases (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 250-250 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Lifson et al.1 and Sodroski et al.2 report that syncytia production by the human immunodeficiency virus (HIV) in susceptible cells is a characteristic feature of infection. They suggest that this type of cell fusion is associated with a differentiation antigen (CD4) and requires only the ...
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    Are 'pragmatypes' acceptable? (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 251-251 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-The rules for the designation of type specimens regularize the procedure for establishing the acceptable names for species. They minimize possibilities for dispute following advances in taxonomic understanding. For example, when a 'species' is found to be two species, which had been confused ...
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    Search for natural isotope superlattices (1987)
    [s.l.] : Nature Publishing Group
    Nature 326 (1987), S. 252-252 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-The search for the formation of superlattice-type structures has yielded a good harvest for condensed matter scientists. Period doublings, commensurate-incommensurate transitions, spontaneous ordering of voids in metals under neutron irradiation, and so forth, all represent examples of ...
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    Amorphous definitions and glasses (1987)
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    Nature 326 (1987), S. 252-252 
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    Notes: [Auszug] SIR-In their recent paper Phillips et al.l present evidence for the existence of su-pernanometric microcystallites in 'amorphous' silicon. We should admit, however, that there are many ways in which a solid does not have to be a crystal: the random network model of the structure of glasses does not ...
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    Chunking by a pigeon in a serial learning task (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 149-151 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In this study, a pigeon's ability to chunk sequential information was evaluated by its performance on a task that required it to produce 5-element lists of arbitrary stimuli3. A hungry pigeon is given food reward if, and only if, it pecks arrays of simultaneously presented colours in a particular ...
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    The spring in the arch of the human foot (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 147-149 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Figure la shows the principal forces that act on the foot in the middle part of the stance phase. The heel is rising from the ground and the centre of pressure for the ground force is on the ball of the foot4. The forces exert bending moments on the foot, tending to flatten the arch. The same ...
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    Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 151-153 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The cutaneous receptive fields of flexor motor neurons expand in size and increase in responsiveness after peripheral tissue injury5'6. Similar effects can be produced by brief conditioning volleys in unmyelinated afferents, with muscle afferents having a more prolonged effect than cutaneous ...
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    Neuronal inhibition by the peptide FMRFamide involves opening of S K + channels (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 153-156 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] By closing the S channels, serotonin produces a slow depolarization of the sensory neuron membrane potential, increases the duration of the action potential arid enhances transmitter release from the terminals of the sensory neuron (presynaptic facilitation)15. FRMFamide produces opposite effects ...
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    Ohmic conductance through the inwardly rectifying K channel and blocking by internal Mg 2+ (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 156-159 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Single ventricular cells were obtained from adult guinea pig hearts by enzymatic dissociation and recordings of currents were performed using a heat-polished patch electrode in the whole cell, cell-attached, and open cell-attached configurations6'8. One difficulty which hampered studies of the ...
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    Inositol trisphosphate receptor localization in brain: variable stoichiometry with protein kinase C (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 159-161 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Ins(l,4,5)P3 binds to rat cerebellar homogenates saturably and with high affinity (Fig. 1 legend). In typical centrifugation binding assays using 2.5 nM 3H-Ins(l,4,5)P3 (NEN-DuPont, 3.6 Ci mmor1), total binding is 2,600 c.p.m. and nonspecific binding, measured in the presence of 1 jxM unlabelled ...
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    Tissue-specific expression of three distinct types of rabbit protein kinase C (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 161-166 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A rabbit cDNA library was screened using synthetic oligonu-cleotide mixtures or fragments of cloned cDNA as probes. Isolated positive clones were classified into three types, a, /3 and y, on the basis of restriction mapping, nucleotide sequencing and Southern hybridization (Fig. la). Because a and ...
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    Stimulation of specific GTP binding and hydrolysis activities in lymphocyte membrane by interleukin-2 (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 166-168 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Particulate membrane fractions were prepared from the IL-2 dependent T lymphocyte cell line CT6, known to express -4,300 high-affinity (Xd = 25 pM) IL-2 receptors per cell21. The addition of IL-2 to these membrane fractions resulted in specific, high- Table 1 Effect of pretreatment of membranes ...
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    Inhibition of phosphorylcholine binding to antibodies using synthetic peptides (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 168-171 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The combining site of an antibody is formed by the three hypervariable or complementarity-determining regions (CDRs) of its heavy and light chains7'8. The nature and shape of the combining site and its interaction with antigen are determined primarily by the amino-acid sequences in the CDRs. Of the ...
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    Association of the polyomavirus middle-T antigen with c- yes protein (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 171-173 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The gene c-yes is the cellular homologue of the v-yes gene carried by the Y73 and Esh avian sarcoma viruses11'13; both genes encode tyrosine protein kinases homologous to the v-src gene product, found in Rous sarcoma virus14'15. The anti-yes antibody recognizes the v-yes protein from Y73-infected ...
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    Photofootprinting in vivo detects transcription-dependent changes in yeast TATA boxes (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 173-177 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Normal transcriptional regulation of the galactose-inducible genes (GAL, 1,7,10) of the yeast Saccharomyces cerevisiae requires the products of two regulatory genes, GAL 4 and GAL 80. As GAL 4-encoded protein is required for induction, it is believed to be a transcriptional activator6'7, and has ...
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