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  • Articles  (47,891)
  • Chemistry  (41,808)
  • Animals  (6,074)
  • Analytical Chemistry and Spectroscopy  (5,741)
  • Mice  (1,566)
  • 2000-2004  (4,622)
  • 1985-1989  (43,269)
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  • Articles  (47,891)
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  • 1
    Electronic Resource
    Electronic Resource
    Circling behavior induced by phencyclidine in mice and its inhibition by naloxone (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 73-74 
    Details
    ISSN: 1420-9071
    Keywords: Mice ; circling behavior ; phencyclidine ; naloxone ; hyperactivity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Phencyclidine (PCP), when given to mice, induces general hyperactivity and rapid circling, similar to that caused by morphine. These effects are partially antagonized by naloxone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02005882
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  • 2
    Electronic Resource
    Electronic Resource
    Antagonistic effect of progesterone towards estradiol dipropionate-induced changes in glycogen content in uterus and vagina of P-mice (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 1455-1456 
    Details
    ISSN: 1420-9071
    Keywords: Mice ; uterus ; vagina ; sex steroids ; glycogen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Estradiol dipropionate induces an increase (3-fold) in the uterine glycogen content and a decrease (4-fold) in the vaginal glycogen content of Parkes (P) mice. Progesterone antagonizes this estradiol dipropionate-induced response in both the uterine and vaginal tissue. The degree of this antagonism is more pronounced in the uterus than in the vagina.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01950032
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  • 3
    Electronic Resource
    Electronic Resource
    Incorporation of32P into renal phospholipids of mice during postnatal growth (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 1184-1186 
    Details
    ISSN: 1420-9071
    Keywords: Mice ; phospholipids ; kidney growth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary During the first 40 days of life the rate of incorporation of32P into total phospholipids and into phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, sphingomyelin, diphosphatidylglycerol, phosphatidic acid and phosphatidylinositol of mouse kidney was by some 25–35% higher than in older animals. Results suggest a different involvement of cellular membranes during of normal and compensatory renal growth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01951720
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  • 4
    Electronic Resource
    Electronic Resource
    Chemistry of high mountain lakes in siliceous chatchments of the Central Eastern Alps (1989)
    Springer
    Aquatic sciences 51 (1989), S. 108-128 
    Details
    ISSN: 1420-9055
    Keywords: Chemistry ; mountain lakes ; silica ; acidity ; sediment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Alpine lakes in siliceous catchments of Tyrol and Carinthia (Austria) show signs of acidification. About 9% of the studied lakes have no alkalinity, more than 20% are below pH 6. About two thirds of all lakes have acid neutralizing capacities below 100 μeq 1−1. In spite of moderate precipitation acidity, some lakes show considerable concentrations of dissolved reactive aluminum during or shortly after snowmelt. High altitude lakes of the Alps are definitely more acidic than high mountain lakes in remote areas. Large differences in water and soil chemistry of nearby situated lakes were attributed to heterogeneities of bedrock geology. Paleolimnological investigations on former pH values of five lakes, based on diatom assemblages in the sediment, showed different developments: recent and past acidification, stable conditions, and alkalinization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00879298
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  • 5
    Electronic Resource
    Electronic Resource
    The consequences of the mutual recognition of measurement standards for international metrology (2000)
    Springer
    Accreditation and quality assurance 5 (2000), S. 409-413 
    Details
    ISSN: 1432-0517
    Keywords: Key words Metrology ; Comparisons ; Chemistry ; Standards
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract  After stressing the importance in the modern world of accurate and reproducible measurements, the actions taken by the Bureau International des Poids et Mesures to set up, together with the regional metrology organizations, a series of key comparisons are described. They are the technical foundation of a mutual recognition of national measurement standards arrangement prepared in conjunction with the National Metrology Institutes (NMIs). This arrangement also includes the recognition of calibration and measurement certificates issued by these institutes. Then, the consequences of this arrangement for trade are described. The case of chemical analysis is illustrated by the application of the Kyoto protocol on the reduction of greenhouse gases. But the global workload to be taken up by the International Committee of Weights and Measures, its Consultative Committee for Amount of Substance and the NMIs is huge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007690000228
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  • 6
    Electronic Resource
    Electronic Resource
    Neutralizing antibody provided protection against enterovirus type 71 lethal challenge in neonatal mice (2000)
    Springer
    Journal of biomedical science 7 (2000), S. 523-528 
    Details
    ISSN: 1423-0127
    Keywords: Enterovirus type 71 ; Experimental infection ; Mice ; Neutralizing antibody ; Vaccine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Experimental infection with enterovirus type 71 (EV71) induced death in neonatal mice in an age- and dose-dependent manner. The mortality rate was 100% following intraperitoneal inoculation 1-day-old ICR mice and this gradually decreased as the age at the time of inoculation increased (60% in 3-day-old mice and no deaths occurred in mice older than 6 days of age). A lethal dose greater than 108 PFU was necessary. Lethargy, failure to gain weight, rear limb tremors and paralysis were observed in the infected mice before death. EV71 was isolated from various tissues of the dead mice. Using a reverse transcription polymerase chain reaction technique with a specific primer pair, a 332-bp product was detected in the tissues that produced a culture positive for EV71. Protection against EV71 challenge in neonatal mice was demonstrated following passive transfer of serum from actively immunized adult mice 1 day after inoculation with the virus. Pups from hyperimmune dams were resistant to EV71 challenge. Additionally, maternal immunization with a formalin-inactivated whole-virus vaccine prolonged the survival of pups after EV71 lethal challenge.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02253368
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  • 7
    Electronic Resource
    Electronic Resource
    Transgenic markers for mammalian chimeras (1988)
    Springer
    Development genes and evolution 197 (1988), S. 63-65 
    Details
    ISSN: 1432-041X
    Keywords: Chimeras ; In situ hybridization ; Mice ; Transgenic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary We describe the construction of aggregation chimeras between normal and transgenic embryos containing multiple copies of mouse β-globin genes. The transgenic component of the chimeras is then detected in tissue sections by a DNA-DNA in situ hybridization technique, using a biotinylated DNA β-globin probe and an avidin-linked alkaline phosphatase detection system. The general advantages of transgenic markers for chimeras are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00375928
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of aminoglutethimide on murine fetal hepatic erythroid colony formation (1985)
    Springer
    Cellular and molecular life sciences 41 (1985), S. 498-500 
    Details
    ISSN: 1420-9071
    Keywords: Mice ; pregnant ; aminoglutethimide phosphate ; mice ; liver ; fetal ; erythroid colony-forming cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Pretreatment of pregnant mice with aminoglutethimide phosphate, an inhibitor of glucocorticoid synthesis, increases the content of fetal liver erythroid colony-forming cells (CFU-E), as assessed by the formation of erythroid colonies in vitro by fetal liver cells in plasma clots containing exogenous erythropoietin. In addition, the inability of aminoglutethimide to influence erythroid colony formation in vitro suggests that endogenous glucocorticoids exert a suppressive effect on the number of functional CFU-E in the fetal liver.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01966168
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  • 9
    Electronic Resource
    Electronic Resource
    Sperm enzyme activity analysis in individual sperm for detection of heritable mutations in mammals (1988)
    Springer
    Cellular and molecular life sciences 44 (1988), S. 253-254 
    Details
    ISSN: 1420-9071
    Keywords: Mice ; heritable mutations ; sperm enzyme activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Male mice were injected i.p. with 2.5 mg/kg mitomycin C, 100 mg/kg ethyl nitrosourea or saline and mated with untreated virgin females five weeks later. Sperm from 64 of the F1 male progeny were analyzed histochemically for acrosin, succinic dehydrogenase and alpha-glycerophosphate dehydrogenase activity. The frequency of F1 males with sub-normal sperm enzyme activity was significantly higher among progeny from treated males than in controls. These results show that analysis of sperm enzyme activity in F1 males is a practical method for detection of transmitted mutations induced in a treated parent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01941727
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  • 10
    Electronic Resource
    Electronic Resource
    Heterosis among lines of mice selected for body weight (1985)
    Springer
    Theoretical and applied genetics 71 (1985), S. 52-56 
    Details
    ISSN: 1432-2242
    Keywords: Heterosis ; Reproduction ; Mice ; Body weight
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary To examine the effect of selection for body weight on levels of heterosis for reproductive traits, crosses were made between three groups of six lines of mice, one group unselected (controls) and the other two selected for high (large lines) and low (small lines) 6-week body weight, respectively. The coefficient of inbreeding of each line was about 0.60. In a comparison of purebred and crossbred progeny, both out of purebred mothers, there was on average 4% heterosis for number born, 3% for percentage weaned and 8% for numbers weaned. In a comparison of purebred and crossbred mothers, each mated to males of an unrelated strain and dissected on the 17th day of gestation, crossbreds had on average 1.6 more live embryos, which was 22% of the purebred mean. This comprised an increase of 0.6 corpora lutea, of 0.4 in survival to implantation and of 0.6 in subsequent survival to 17 days. The heterosis was similar whether the mothers had parents of the same or different size.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00278253
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