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  • bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general  (1,059)
  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences  (405)
  • Chemical Engineering
  • Inorganic Chemistry
  • Organic Chemistry
  • MDPI - Multidisciplinary Digital Publishing Institute  (1,464)
  • Wiley-Blackwell
  • 2020-2024  (1,465)
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This reprint is the printed edition of the Special Issue published in Materials. The reprint provides an overview on current international research activities in the field of advanced pulse laser machining technology. It covers fundamental and applied aspects and collects contributions of renowned scientists from academics and industries working in the fields of laser processing, materials science, physics, chemistry, and engineering in order to foster the current knowledge and present new ideas for future applications and new technologies.
    Keywords: multi-beam micromachining ; beam splitting ; invar ; shadow masks ; OLED ; nanosecond laser ; direct laser interference patterning ; design of experiments ; central composite design ; morphological filtering ; surface texture homogeneity ; micro structuring ; bearing steel ; dual laser beam processing ; excited state absorption ; semiconducting thin films ; stimulated emission depletion ; femtosecond laser ; silicon ; amorphization ; crystallization ; spectroscopic imaging ellipsometry ; transmission electron microscopy ; atomic force microscopy ; laser ablation ; ultrafast ; re-deposition ; fs-laser writing ; waveguides ; element redistribution ; Soret effect ; diffusion competition effects ; ultra-short pulses ; double pulses ; burst processing ; MHz bursts ; GHz bursts ; X-ray emission ; micromachining ; dose rate ; X-ray spectrum ; ultrafast laser ; laser ; ultrashort pulse ; plasma ; X-ray ; Bremsstrahlung ; resonance absorption ; burst ; bi-burst ; beam shaping ; squared top-hat ; fs-laser ; laser surface structuring ; laser-induced periodic surface structures ; micro-channels ; glass ; ultrafast laser processing ; Bessel beam ; X-ray emission hazards ; ultrashort pulsed laser ; radiation protection ; industrial applications ; protection housing ; ambient dose rate ; pulsed laser ; laser micromachining ; mechanical shutter ; solenoid shutter ; electro-optic modulator shutter ; opening time ; lifetime ; X-ray energies ; X-ray dose rate ; laser printing ; laser-induced forward transfer (LIFT) ; digital manufacturing ; additive manufacturing ; printing of materials ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 2
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Global warming is imposing tremendous challenges upon human and otherwise biotic life on Earth. A warmer atmosphere holds more moisture. The consensus is that the moisture transport by the atmospheric circulation strengthens and makes already wet areas of moisture convergence wetter and already dry areas of moisture divergence drier. Therefore, the tropics and mid-to-high latitudes will get wetter and the subtropics will get drier. Without any change in the interannual variability of hydroclimate, the change in the mean hydroclimate would equally increase drought risk in some places and flood risk in others. Moreover, global warming will cause the interannual variability of the hydroclimate to intensify, which will induce more droughts and floods. Furthermore, the changing atmospheric circulation interaction with the land surface may cause storm track alterations and may play an important role in shaping moisture redistribution. The author's contributions have documented the precipitation trends in southeast of the US, the Nile River Basin Ethiopia, Iraq, the Huai River Basin of northern China, and the Qilian Mountains of western China. The precipitation predictability on both global and regional scales are also studied. The interaction among climate systems in southeast Asia is also explicitly documented.
    Keywords: El Niño ; winter weather types ; precipitable water ; surface water vapor pressure ; consistency ; interannual and long-term trend ; precipitation ; trend analysis ; Iraq ; climate projection ; CMIP5 ; groundwater levels ; rainfall ; temperature ; Mann–Kendall test ; Bayesian Ensemble Algorithm ; rainstorm process ; rainstorm intensity ; risk estimation and mapping ; CMIP6 ; risk prediction ; Southwest China ; rainstorm and flood ; spatial and temporal change ; atmospheric circulation ; rainfall change ; CHIRPS ; PERSIANN-CDR ; descriptive statistics ; non-parametric trends ; Google Earth Engine ; central Punjab ; climate change ; land cover/land use ; vegetation ; NDVI ; Huai River Basin ; trends and variability ; flood magnitude ; Qilian Mountains ; cyclones power dissipation index (PDI) ; monsoon trough ; El Niño southern oscillation (ENSO) ; Indian Ocean dipole (IOD) ; Walker circulation ; predictability ; global ; seasonal precipitation ; ENSO ; MJO ; climate trend ; land use land cover ; Nile River Basin ; water resources ; raindrop spectrum ; radar ; dynamic Z-I ; LSTM neural network ; precipitation estimation ; Loess Plateau ; spring maize ; relative soil moisture ; drought index ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RB Earth sciences::RBP Meteorology & climatology
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: Landscapes and cultural heritage have faced many challenges over time, including modifications and degradation that appear with time, overlaps with other challenges not previously observed, and the influence of cities and management. One of the most visible and globally discussed challenges is climate change. Therefore, there is an urgent need to launch initiatives to tackle climate change and other current challenges from the perspective of landscape and cultural heritage protection. This Special Issue presents selected papers of studies conducted in relation to the 28th Conference on the Series of Garden Art and Historical Dendrology entitled “Climate Change and Current Challenges for Landscapes and Cultural Heritage” that was held on 28 and 29 October 2021. This collection serves as a platform for the exchange of experiences among researchers from different scientific domains.
    Keywords: nature reserves ; landscape fragmentation ; north–south transitional zone ; spatial differentiation ; Qinling–Daba Mountains ; habitat quality ; water dams ; Krakow fortress ; climate change ; environmental management ; cultural heritage conservation ; urban densification ; prefabricated housing estates ; spatial devastation ; protection of urban layout ; Cracow ; climate change mitigation ; cultural heritage ; urban renewal ; urban parks ; therapeutic landscapes ; climate resilience ; vernacular heritage ; climate narratives ; climate adaptation ; climate stories ; courtyard ; urban green infrastructure ; urban pattern ; supervised classification ; ecosystem services (ES) ; urban cemeteries ; biocultural diversity (BCD) ; urban green infrastructure (UGI) ; questionnaire survey ; Leipzig ; Łódź ; sensory gardens ; urban green spaces ; aromatic herbs ; plant smell memory ; stress ; human wellbeing in urban areas ; restorative environments ; history of gardens ; castle garden ; goosefoot avenue ; star-shaped garden layout ; Austro-Hungarian Empire ; Transylvania as part of Romania ; green infrastructure ; resilience management ; biodiversity ; scenario analysis ; cellular automata model ; historic psychiatric hospitals ; therapeutic landscape ; green therapy ; horticulture therapy ; historical commons ; human cultural heritage ; local development ; landscape values ; rainwater management ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Anthropogenic greenhouse gas (GHG) emissions are dramatically influencing the environment, and research is strongly committed to proposing alternatives, mainly based on renewable energy sources. Low GHG electricity production from renewables is well established but issues of grid balancing are limiting their application. Energy storage is a key topic for the further deployment of renewable energy production. Besides batteries and other types of electrical storage, electrofuels and bioderived fuels may offer suitable alternatives in some specific scenarios. This Special Issue includes contributions on the energy conversion technologies and use, energy storage, technologies integration, e-fuels, and pilot and large-scale applications.
    Keywords: Q1-390 ; QC1-999 ; n/a ; PV ; GHG savings ; lithium-ion battery (LIB) ; probability prediction ; decarbonization ; supercapacitor (SC) ; least squares support vector machine ; EV fleet forecasts ; alternative maritime power (AMP) ; Markov chain ; feasibility study ; D funding ; hybrid power system ; numerical analysis ; ship structure ; optimal sizing ; cellulosic ethanol ; electric vehicles EV ; biofuel ; green ship ; R&amp ; bulk carrier ; molten carbonate fuel cell system ; sparse Gaussian process regression ; power-to-gas ; combination method ; charging infrastructure ; jet fuel ; flow characteristics ; hybrid refinery ; LNG-fueled ship ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Wildfire risk can be perceived as the combination of wildfire hazards (often described by likelihood and intensity) with the susceptibility of people, property, or other valued resources to that hazard. Reflecting the seriousness of wildfire risk to communities around the world, substantial resources are devoted to assessing wildfire hazards and risks. Wildfire hazard and risk assessments are conducted at a wide range of scales, from localized to nationwide, and are often intended to communicate and support decision making about risks, including the prioritization of scarce resources. Improvements in the underlying science of wildfire hazard and risk assessment and in the development, communication, and application of these assessments support effective decisions made on all aspects of societal adaptations to wildfire, including decisions about the prevention, mitigation, and suppression of wildfire risks. To support such efforts, this Special Issue of the journal Fire compiles articles on the understanding, modeling, and addressing of wildfire risks to homes, water resources, firefighters, and landscapes.
    Keywords: wildfire risk ; object-oriented image analysis ; Sentinel-2 ; fire behavior ; flammap ; wildfire management ; water supply ; erosion ; wildfire containment ; Potential fire Operational Delineations ; Monte Carlo simulation ; transmission risk ; WUI ; fire ; defensible space ; prescribed fire ; community vulnerability ; fire suppression costs ; Zillow ; wildfire ; predictive modeling ; fire spread model ; Monte Carlo ; spatial modeling ; area difference index ; statistics ; precision ; recall ; principal components analysis ; risk assessment ; structure loss ; wildland–urban interface ; mitigation ; mapping ; land use ; disaster ; fire spread models ; surrogate modeling ; sensitivity analysis ; global sensitivity analysis ; colour coding ; communication ; forest fire ; ordinal categorization ; palette ; risk ; firefighter safety ; safe separation distance ; safety zones ; LCES ; Google Earth Engine ; lidar ; LANDFIRE ; Landsat ; GEDI ; parcel-level risk ; post-fire analysis ; risk mitigation ; rapid assessment ; natural hazards ; fuels ; fire hazard ; remote sensing ; LiDAR ; Sentinel ; modeling ; simulation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: The purpose of this Special Issue was to collect and present research results and experiences on energy supply in the Visegrad Group countries. This research considers both macroeconomic and microeconomic aspects. It was important to determine how the V4 countries deal with energy management, how they have undergone or are undergoing energy transformation and in what direction they are heading. The articles concerned aspects of the energy balance in the V4 countries compared to the EU, including the production of renewable energy, as well as changes in its individual sectors (transport and food production). The energy efficiency of low-emission vehicles in public transport and goods deliveries are also discussed, as well as the energy efficiency of farms and energy storage facilities and the impact of the energy sector on the quality of the environment.
    Keywords: energy supplies ; energy security ; energy market ; EU countries ; Hellwig’s method ; sustainability strategies ; sustainable development ; Visegrád Group ; sustainable strategic management ; the renewable energy sector ; energy use ; structures ; food production systems ; Visegrad Group ; energy mix ; renewables ; energy in transport ; energetic efficiency ; energy sources ; economic growth ; developing and developed countries ; energy sector ; environmental quality ; renewable energy sources (RES) ; nuclear energy ; southeastern Poland ; sustainability ; renewable energy sources ; European Union ; cluster analysis ; Visegrad Group countries ; fuels ; cointegration ; Granger causality ; electricity prices ; households ; directions of price changes ; biogas energy ; solar energy ; hybrid biogas plant ; renewable energy ; circular economy ; off-grid systems ; energy efficiency ; social and economic aspects of energy ; economic efficiency ; low emissions ; zero emissions ; e-commerce ; last mile ; parcel lockers ; efficiency of logistics processes ; economies of scale ; simulation of logistics processes ; COVID-19 ; BESS management ; price arbitration ; shift load ; microgrid ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Language: English
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: This Special Issue, “Mapping Indigenous Knowledge in the Digital Age”, explores Indigenous engagement with geo-information in contemporary cartography. Indigenous mapping, incorporating performance, process, product, and positionality as well as tangible and intangible heritage, is speedily entering the domain of cartography, and digital technology is facilitating the engagement of communities in mapping their own locational stories, histories, cultural heritage, environmental, and political priorities. In this publication, multimodal and multisensory online maps combine the latest multimedia and telecommunications technology to examine data and support qualitative and quantitative research, as well as to present and store a wide range of temporal/spatial information and archival materials in innovative interactive storytelling formats. It will be of particular interest to researchers engaged in studies of global human and environmental connection in the age of evolving information technology.
    Keywords: transdisciplinary research ; knowledge dialog ; participatory mapping ; qualitative analysis ; community-based management ; Dawes ; allotment ; GIS ; map ; automation ; PLSS ; geographic information systems ; reservation ; indigenous ; Standing Rock ; community mapping ; learning community ; natural resources management ; Cyberatlas ; Native Americans ; first nations ; historic cartography ; toponymy ; Indigenous maps ; indigital ; undergraduate education ; native science ; Inuinnait ; Inuinnaqtun ; cybercartography ; digital return ; multi-media cartography ; digital heritage ; native guidance system ; Lençóis Maranhenses region ; Maranhão coast ; traditional communities ; Cybercartographic Atlas ; indigenous mappings ; decolonial cartography ; mythical spaces and indigenous orientations ; sky map ; collaborative work ; Pa Ipai ; Baja California ; Mexico ; mapping ; reconciliation ; art ; digital pedagogy ; reflexivity ; Cybercartography ; GIAMedia ; FOSS ; intercultural literacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment, suitably designed to be a similar as possible to cellular conditions. This Special Issue provides readers with a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to be used as traces for the discoveries of some relevant biological processes. Several subjects are presented, with five articles and five reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications and bioinspired synthesis, with “free radicals” as the common denominator.
    Keywords: guanine ; guanyl radical ; tautomerism ; guanine radical cation ; oligonucleotides ; DNA ; G-quadruplex ; time-resolved spectroscopies ; reactive oxygen species (ROS) ; oxidation ; catalase mimics ; peroxide ; diiron-peroxo complexes ; structure/activity ; kinetic studies ; biomimetic chemistry ; cysteine ; ketone reduction ; free radicals ; pulse radiolysis ; kinetics ; DNA oxidation ; DNA hole transfer ; molecular dynamics ; quantum dynamics ; electron transfer ; charge transfer ; quantum coherence ; chemiluminescence ; reaction mechanisms ; singlet oxygen ; reactive oxygen species ; light emission ; crosslink ; dimerization ; protein oxidation ; radicals ; di-tyrosine ; di-tryptophan ; disulfides ; thiols ; aggregation ; proteomics ; mass spectrometry ; collagen ; riboflavin ; hyaluronic acid ; EPR spectroscopy ; keratoconus ; STEM ; DNA biosensor ; chemical nucleases ; DNA-drug interaction ; copper complexes ; metallodrugs ; MEP pathway ; antibiotics ; IspH ; LytB ; [4Fe-4S] cluster ; reductive dehydroxylation ; bioorganometallic intermediate ; inhibitors ; methionine ; neighboring group effect ; hydroxyl radical ; triplet state of carboxybenzophenone ; one-electron oxidants ; laser flash photolysis ; peptides ; proteins ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: This Special Issue highlights fundamental changes to the questions that we can ask about both the recent past and deep time. Delve into the forefront of paleontological research with this Special Issue reprint. Renowned paleontologists from around the world share groundbreaking insights into ancient life on Earth. Discover the latest advances in fossil discovery, analytical techniques, interdisciplinary collaborations, and technological innovations that are shaping our understanding of evolution and the Earth's history. This collection of cutting-edge research is a must-read for scientists, researchers, and enthusiasts interested in the dynamic field of paleontology in the modern era.
    Keywords: REE ; Tyrannosaurus rex ; molecular paleontology ; geochemical taphonomy ; diagenesis ; bone ; protein ; collagen ; Hell Creek Formation ; cuticle ; Eocene ; Fur Formation ; insects ; melanin ; mo-clay ; pigment ; Stolleklint Clay ; structural coloration ; Ølst Formation ; fossil ; dinosaur ; paleoproteomics ; porphyrin ; keratin ; feather ; taphonomy ; degradation ; microbes ; CO2 ; apatite ; paleontology ; China ; history ; 20th century ; 21th century ; paleobiology ; history and philosophy of paleontology ; twenty-first-century paleontology ; paleobiological revolution ; technoscience and global issues ; fossil proteins ; rare earth elements ; soft-tissue preservation ; geochemistry ; soft tissues ; molecular preservation ; Hornerstown Formation ; shallow marine ; glauconite ; hybridization ; introgression ; ancient DNA (aDNA) ; hominin paleontology ; paleoanthropology ; Brachylophosaurus ; Judith River Formation ; ELISA ; RIA ; Venta Micena site ; VM-0 ; VM-1960 ; taxonomy ; morphometrics ; phylogeny ; evolution ; morphological clock ; molecular clock ; biodiversity ; palaeobiogeography ; macroevolution ; primates ; Cercopithecidae ; monkeys ; genotype:phenotype mapping ; dentition ; Equidae ; Equinae ; hipparionini ; protohippini ; equini ; paleoecology ; paleoclimatology ; biochronology ; steroids ; diet ; coprolites ; Gryphaea dilatata ; crystallographic texture ; pole figures ; neutron diffraction ; recrystallization ; thick-walled shells ; molecular taphonomy ; fossils ; preservation ; mass spectrometry ; dinosaurs ; Neanderthal ; Combe-Grenal ; juvenile ; mandible ; periodontitis ; tooth ; tartar ; SEM analysis ; n/a ; terrestrialization ; artrhopods ; Cambrian explosion ; molecular clocks ; palaeontology ; phylogenomics ; teeth ; enamel ; microanalysis ; Purussaurus ; Neoepiblema ; miocene ; ICP-MS ; MEV ; microscopy ; magnetic resonance imaging ; micro-computed tomography ; radiocarbon dating ; DNA barcoding ; synchrotron ; bone remodeling ; elemental analysis ; diagenetic alteration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 10
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This Special Issue introduces recent research results on MEMS packaging and 3D integration whose subjects can be divided as follow; three papers on biocompatible implantable packaging, three papers on interconnect, three papers on bonding technologies, one paper on vacuum packaging, and three papers on modeling and simulation.
    Keywords: heterogeneous integration ; wafer bonding ; wafer sealing ; room-temperature bonding ; Au-Au bonding ; surface activated bonding ; Au film thickness ; surface roughness ; microelectromechanical systems (MEMS) packaging ; inkjet printing ; redistribution layers ; capacitive micromachined ultrasound transducers (CMUT) ; fan-out wafer-level packaging (FOWLP) ; adhesion ; thin film metal ; parylene ; neural probe ; scotch tape test ; FEM ; MEMS resonator ; temperature coefficient ; thermal stress ; millimeter-wave ; redundant TSV ; equivalent circuit model ; S-parameters extraction ; technology evaluation ; MEMS and IC integration ; MCDM ; fuzzy AHP ; fuzzy VIKOR ; fan-out wafer-level package ; finite element ; glass substrate ; reliability life ; packaging-on-packaging ; thermal sensors ; TMOS sensor ; finite difference time domain ; optical and electromagnetics simulations ; finite element analysis ; ultrasonic bonding ; metal direct bonding ; microsystem integration ; biocompatible packaging ; implantable ; reliability ; Finite element method (FEM) ; simulation ; multilayer reactive bonding ; integrated nanostructure-multilayer reactive system ; spontaneous self-ignition ; self-propagating exothermic reaction ; Pd/Al reactive multilayer system ; Ni/Al reactive multilayer system ; low-temperature MEMS packaging ; crack propagation ; microbump ; deflection angle ; stress intensity factor (SIF) ; polymer packaging ; neural interface ; chronic implantation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-11-17
    Description: Symmetry can play an important role in the field of nonlinear systems and especially in the design of nonlinear circuits that produce chaos. Therefore, this Special Issue, titled “Symmetry in Chaotic Systems and Circuits”, presents the latest scientific advances in nonlinear chaotic systems and circuits that introduce various kinds of symmetries. Applications of chaotic systems and circuits with symmetries, or with a deliberate lack of symmetry, are also presented in this Special Issue. The volume contains 14 published papers from authors around the world. This reflects the high impact of this Special Issue.
    Keywords: chaos ; bifurcation ; closed curve equilibrium ; synchronization ; nonlinear equations ; iterative methods ; rotation–translation formula ; symmetric encryption ; chaotic map ; image encryption ; simultaneous confusion and diffusion ; chaotic oscillator ; lyapunov exponents ; poincare map ; integrated circuit ; fpga ; time-delay ; boolean networks ; hidden attractor ; amplitude control ; offset boosting ; cryptography ; substitution box ; postprocessing ; symmetry ; asymmetry ; chaotic system ; random bit generation ; logistic map ; chaos-based cryptography ; entropy ; prediction ; fractional-order ; glucose-insulin system ; chaotic attractor ; active control ; chaos theory ; electrical circuit analysis ; jerk circuit ; Chua’s diode ; system of differential equations ; quantum mechanics ; molecular quantum transitions ; singularity ; dozy chaos ; dozy-chaos mechanics ; charge transfer ; condensed matter ; direct and reverse processes ; optical band shapes ; Egorov resonance ; hyperchaotic behavior ; arduino microcontrollers ; optical channel ; chaotic flow ; hyperbolic sinusoidal function ; voice encryption ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The World Health Organization recommends the consumption of plant foods instead of animal-origin foods due to their high levels of saturated fat and cholesterol. Consumption of plant products has led to research on the beneficial properties of their components beyond basic nutrients. Vegetable-derived peptides have shown multifunctional effects related to chronic diseases, attracting interest from the food, nutraceutical, and pharmaceutical industries. This reprint highlights studies on various vegetable extracts, such as chestnut, quinoa, amaranth, buckwheat, and Protium heptaphyllum gum resin, which have demonstrated antimicrobial, anti-inflammatory, and cholesterol-regulating properties. Specific compounds derived from plants, such as methyl p-coumarate and lupin protein hydrolysate, have shown effectiveness in reducing inflammation and anxiety, respectively. A vegetable extract of rosemary has been studied for its potential to treat osteogenesis imperfecta. Moreover, this repprint reviews Lycium barbarum berries, essential oils from Annonaceae species, antioxidant compounds, phytosterols, and natural compounds for the prevention and treatment of oral mucositis was discussed. Overall, these studies suggest that vegetable-derived bioactive compounds could serve as new nutraceuticals to prevent and treat a wide range of chronic diseases.
    Keywords: hypercholesterolemia ; gene expression ; HMGCR ; PCSK9 ; PPARα ; enzymatic activity ; molecular docking ; statin ; monacolin ; breu branco ; seed storage proteins ; peptides ; anti-inflammatory ; antioxidant ; trypsin inhibitors ; quinoa ; amaranth ; buckwheat ; in vitro gastro-intestinal digestion ; natural products ; Brazilian species ; essential oil ; applications ; phytosterols ; neurodegeneration ; Alzheimer’s disease ; blood brain barrier ; obesity ; oxidative stress ; dyslipidemia ; diabetes ; enzyme-assisted extraction ; plant material ; phenolic compounds ; oligosaccharides ; prebiotic ; nanocellulose ; nanofibers ; fermentation ; sustainability ; cancer ; drug delivery ; oral mucositis ; treatment ; lupin ; protein hydrolysates ; anxiety ; ApoE−/− ; functional foods ; peptidomics ; rosemary extract ; collagen type I ; unfolded protein response ; autophagy ; proteasome ; skin fibroblasts ; apoptosis ; osteogenesis imperfecta ; asthma ; methyl p-coumarate ; Th2 cytokines ; eosinophil ; NF-κB ; Castanea sativa shells ; Subcritical Water Extraction (SWE) ; antimicrobial activity ; goji berries ; pro-healthy effects ; phenolics ; biological properties ; functional ingredients ; in vitro cultures ; Ruta montana ; coumarins ; alkaloids ; antibiofilm formation ; antibacterial activity ; antioxidant activity ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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  • 13
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Keywords: QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Considering the worldwide problem of aquatic pollution, we proposed this reprint, which presents a collection of articles on different aspects of environmental pollution, from monitoring to the evaluation of toxicity. In particular, the volume concerns the issues specifically related to emerging contaminants in aquatic environments, such as plastics and pharmaceuticals. However, to confer to this volume a more holistic view, some articles on priority pollutants, such as heavy metals and pesticides, are also reported.
    Keywords: aquatic ecosystems ; pollution ; monitoring ; toxic effects ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This Special Issue of the journal Axioms collects submissions in which the authors report their perceptions and results in the field of mathematical physics and/or physical mathematics without any preconditions of the specific research topic. The papers are intended to provide the reader with a broad window into the status of the research field showing our understanding of how a known concept changes our thinking in that area of science. The papers in the Special Issue highlight the current two issues in physics and mathematics under hot debate: fractional calculus and entropy.
    Keywords: weak detonation ; high activation regime ; nonlinear PDEs ; Fuchsian reduction analysis ; Lorentz transformation ; blow-up ; hot spot ; chemically reactive flows ; nonlinear equations in partial derivatives ; hyperbolic equations ; Bäcklund transformations ; Clairin’s method ; differential relationships ; the Liouville equation ; symbolic calculus ; canonical system of q-difference equations ; q-Euler integral ; multi-term fractional differential equation ; quasilinear equation ; Riemann–Liouville fractional derivative ; defect of Cauchy type problem ; fixed point theorem ; initial-boundary value problem ; deformed numbers ; deformed algebras ; deformed calculus ; nonadditive entropy ; vibration control ; boundary control ; intermediate state control ; separation of variables ; Riemann–Liouville fractional differential equations ; nonlocal boundary conditions ; positive parameters ; positive solutions ; existence ; nonexistence ; Patlak–Keller–Segel systems ; the Cattaneo model of chemosensitive movement ; hyperbolic models ; shock waves ; conservation laws ; constrained Hamiltonian system ; canonicalization ; symplectic method ; numerical simulation ; extended Chebyshev functional ; generalized proportional Hadamard fractional integral operator ; manipulation system ; geometric approach ; noninteraction ; two-phase flow ; Sobolev spaces ; analytic semigroups ; fractional interpolation ; local and global solutions ; seismic tensorial force ; far-field seismic waves ; near-field seismic waves ; seismic mainshock ; quasi-static deformations ; mathematical physics ; Elliott Lieb ; the International Association of Mathematical Physics (IAMP, history and development) ; Letters in Mathematical Physics (LMP) ; history ; God as an (optional) axiom ; metamathematics ; symmetries ; particle physics ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBT Probability & statistics
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-07-06
    Description: The first experiments on electron scattering were completed before the “official” discovery of this particle by J. J. Thomson. In spite of this, our knowledge of cross sections is still far from complete.More recent experiments had some unexpected results, like selective fragmentation of DNA constituents by low-energy electrons, or “reverse” phenomena, i.e., synthesis of simple amino acids from inorganic precursors, triggered by slow electrons. The most recent need for cross sections comes from modeling plasmas for industrial and thermonuclear applications, and atmospheres of solar and extra-solar planets.Both fundamental research (experiments, theory, reviews) and applications of electron-scattering cross sections in various processes are welcome.
    Keywords: ionization ; electron ; positron ; few body ; electron scattering ; integral cross sections ; alcohols ; isomeric effect ; butanol ; pentanol ; electron mobility ; multiple-scattering effects ; disordered systems ; weak localization ; electron and positron scattering ; spin asymmetry ; critical minima ; total polarization ; coulomb glory ; water ; vibrational excitation ; R-matrix ; electron-molecule collisions ; interstellar medium ; model potential ; wave-packet propagation ; vibrational cross-section ; backscattering ; electron optics ; inelastic collisions ; numerical simulations ; electron ionization ; electron capture ; helium droplets ; cross section ; MCDF wavefunctions ; wavelengths ; transition rates ; relativistic distorted wave method ; cross sections ; rate coefficients ; ionizing radiation ; dissociative electron attachment ; mass spectrometry ; DNA damage ; cross-section calculations ; plasma simulation ; electron atomic collisions ; ionization cross section ; approximation of cross sections ; alkali metals ; noble gases ; electron elastic scattering ; scattering cross-sections ; positron scattering ; total cross-sections ; dispersion relation ; electron scattering cross sections ; electron transport in gases ; electron track simulation ; positron impact ionization ; positron-molecule scattering ; binary-encounter-Bethe ; argon optical emission spectroscopy ; plasma processing ; coronal models ; collisional-radiative model ; nonlocal thermodynamic equilibrium plasmas ; population kinetics ; radiation transport ; opacity effects ; Non-Maxwellian plasmas ; metastable states ; electron-impact ionization ; BEB approach ; elementary processes in plasmas ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 17
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-07-06
    Description: It is our pleasure to present this Special Issue of Molecules entitled “Food Processing and Its Impact on Phenolic and other Bioactive Constituents in Food”. Bioactive compounds including phenolic ingredients have long been used as important constituents of a healthy diet. As a result, consumer awareness about the important role of high-quality products rich in bioactive compounds—especially phenolic compounds—in human nutrition, health, and prevention against diseases has increased. Additionally, methods for food processing, regardless of the technology used, have a huge impact on the quality of the final products. Therefore, the big challenges for scientists lie in the monitoring of changes during food processing and the optimization of technology to achieve the minimal degradation of nutrients (including phenolic compounds). Thus, for this Special Issue, I encourage you to read some interesting papers aimed at bringing the latest scientific news, insights, and advances in the field of food processing and its impact on bioactive constituents in food, especially phenolic compounds. The information presented will certainly arouse considerable interest among a large group of our readers from different disciplines and research fields.
    Keywords: apple ; phenolic compounds ; genetic resources ; HPLC-DAD ; thyme ; oregano ; dry herbs ; polyphenols ; chlorophyll ; carotenoids ; microbial ; cytotoxicity ; dissolution test ; functional food ; innovative food ; drying ; natural food ; Helianthus tuberosus ; pro-healthy properties ; plant polyphenols ; food processing ; phenolic content ; bioavailability ; bioaccessibility ; coffee Arabica ; roasting process ; brewing methods ; antioxidant activity ; flavonoids ; caffeine ; pH of infusions ; tannins ; snack ; baking ; carotenoids content ; chlorophyll content ; total polyphenols content ; calorific value ; sensory properties ; sourdough fermentation ; inoculation ; lactic acid bacteria ; FODMAP ; fructans ; antioxidants ; chocolate ; free radical scavenging activity ; reducing power ; functionalization of food ; electronic nose analysis ; isoflavone conversion ; thermal process ; immature seeds ; mature seeds ; internal water content ; konjac ; linseed flour ; fat substitute ; volatile compounds ; lipid oxidation ; encapsulation ; Mauritia flexuosa (aguaje) ; controlled dehydration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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  • 18
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: The eradication of vector-borne diseases is threatened by the limited range of available insecticides, leading, inevitably, to the development of resistance. This is particularly concerning for malaria control, which relies heavily on insecticide-treated nets (ITNs) and indoor residual sprays (IRS). New chemistries are being developed, and innovative deployment of insecticides may play a role in overcoming resistance, either through new types of tools or new means of distribution. A variety of novel product types and vector control strategies are under development and evaluation, which is to be celebrated, but a strong evidence base is needed to guide effective operational deployment decisions. Novel approaches should be supported by robust data collected using appropriate and validated methods to monitor efficacy, durability, and any emerging resistance. This reprint presents original research into developing and characterizing new vector control products, as well as understanding and monitoring insecticide resistance. Review articles explore the impact of insecticide resistance and offer guidance on insecticide choice in the face of pyrethroid resistance. Consensus methodologies are presented, in the form of standard operating procedures (SOPs) designed to be adopted and used to generate reproducible data that can be compared and interpreted across and between studies. It is hoped that this collection of articles offers inspiration and guidance on how consistent data can be generated to inform more effective development, evaluation, and use of new and existing vector control tools.
    Keywords: prallethrin ; insecticide ; spatial treatment ; mosquito fitness ; protection ; pyrethroids ; Aedes albopictus ; Culex pipiens ; life tables ; mosquito ; bite-proof garment ; model ; textile ; non-insecticidal ; physical barrier ; insecticide selection ; out-crossing ; strain authentication ; laboratory screening ; pyrethroid ; pyrethroid resistance ; insecticide resistance ; insecticide resistance management ; vector control ; malaria ; malaria control ; Anopheles ; host-seeking behavior ; insecticide exposure ; pathogen transmission ; Aedes aegypti ; Anopheles gambiae ; ATSB ; Culex quinquefasciatus ; Iroquois ; RNAi ; Saccharomyces cerevisiae ; yeast ; Anopheles mosquito ; fertility ; ovary development ; pyriproxyfen (PPF) ; side-effects ; machine learning ; image classification ; automated identification ; convolutional neural network ; insecticide-treated net (ITN) ; PBO ITN ; synergist ITN ; dual-AI ITN ; insecticide resistance management (IRM) ; method validation ; durability monitoring ; bioinsecticide ; disease transmission ; insecticide-resistance ; mosquito-borne disease ; mosquito control ; natural compounds ; phytochemical ; malaria vector ; insecticide treated nets ; cytochrome P450s ; kdr ; cuticular resistance ; deltamethrin ; imidacloprid ; bifenthrin ; β-cyfluthrin ; etofenprox ; α-cypermethrin ; λ-cyhalothrin ; thiacloprid ; mosquitoes ; Attractive Toxic Sugar Bait (ATSB) ; Attractive Targeted Sugar Bait (ATSB) ; diagnostic bioassay ; resistance monitoring ; insecticide-treated nets (ITN) ; strain characterisation ; method development ; product evaluation ; quality control (QC) ; dual active ingredients (dual-AI) ; bioefficacy ; IRS ; application technology ; broflanilide ; clothianidin ; pirimiphos-methyl ; WHO tube ; WHO tunnel test ; ITNs ; interceptor ; interceptor G2 ; membrane ; human arm ; rabbit ; bioassay ; bio-efficacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Phenolic compounds in food such as fruits, vegetables, wine, spices, and oils have been characterized and their possible effects on human health has been studied in depth. Several technological aspects have also been considered concerning the sustainable extraction of phenolic compounds, the long-term storage effects, and the influence of fermentation and boiling techniques on their properties.
    Keywords: chestnut ; water curing ; non-targeted MS analysis ; antioxidants ; Arecaceae ; polyphenols ; volatile content ; antioxidant activity ; liquid chromatography ; inflammation ; lung ; oxidative damage ; antiviral ; polyphenol ; phenolic acids ; flavonoids ; Vicia faba ; functional food ; green solvents ; biologically active compounds ; selective separation ; medicinal plants ; ultrasonic-assisted extraction ; microwave-assisted extraction ; kombucha ; black tea ; long-term storage ; antioxidant scavenging activity ; total phenolic content ; meat quality ; antimicrobial activity ; C. scolymus ; food quality ; beverages ; health properties ; antioxidant activities ; fibrinogen ; albumin ; rutin ; tannic acid ; resveratrol ; binding properties ; first order ; kinetic modelling ; zero order ; food processing ; herbal tea ; boiling ; EVOO ; vegetables ; phenolic compounds ; thermal treatment ; processing techniques ; bioaccessibility ; bioavailability ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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  • 20
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-07-06
    Description: The articles in this Special Issue cover a very wide range of topics related to the cultivation, management and use of fast-growing tree species. In addition to research on breeding and on the influence of pruning practices on the height growth of paulownia, three articles deal with the influence of site characteristics and nutrient availability on the physiology and yield security of fast-growing tree species. Another article focuses on the modeling of soil carbon in Salix plantations, while the article by Boruszewski et al. reports on potentially suitable areas for the planting of fast-growing tree species in Poland. Zitzmann and Rode examine the impact of short-rotation plantation management on phytodiversity, while Helbig et al. deal with the influence of leaf feeding on the growth of poplars and willows. Finally, Hernandez-Estrada et al. describe the dry matter loss of poplar wood chips during storage.
    Keywords: woody biomass crops ; bioenergy ; biodiversity ; species richness ; flora ; vascular plants ; short rotation coppices ; poplars ; willows ; feeding simulation ; defoliation ; herbivory ; short rotation coppice ; phosphatase activity ; nutrient content ; growth stages ; biomass ; willow ; Salix ; capacity ; European larch ; fast-growing trees ; plantations ; plantation area ; poplar cultivar “Hybrid 275” ; sown area ; biomass production ; life cycle assessment ; climate impact ; soil organic carbon ; genotypic difference ; CRISPR/Cas9 ; genome editing ; Populus ; INRA 717-1B4 ; pyramidal plant habitus ; leaf petiole angle ; branch angle ; nitrogen ; phosphorus ; carbon ; physiology ; F. mandshurica ; Robinia pseudoacacia L. ; photosynthetic vitality ; chlorophyll and phenol content ; nutrition supply ; dry matter yield ; land reclamation ; spring pruning ; year-long pruning ; branching ; angle diversion of sprout ; dry matter losses ; poplar wood chips ; laboratory scale ; cultivable saproxylic microbiota ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
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  • 21
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: This book presents the advances in plant salinity stress and tolerance, including mechanistic insights revealed using powerful molecular tools and multi-omics and gene functions studied by genetic engineering and advanced biotechnological methods. Additionally, the use of plant growth-promoting rhizobacteria in the improvement of plant salinity tolerance and the underlying mechanisms and progress in breeding for salinity-tolerant rice are comprehensively discussed. Clearly, the published data have contributed to the significant progress in expanding our knowledge in the field of plant salinity stress and the results are valuable in developing salinity-stress-tolerant crops; in benefiting their quality and productivity; and eventually, in supporting the sustainability of the world food supply.
    Keywords: watermelon ; salt stress ; RNA-seq ; amino acids ; endocytosis ; Arabidopsis thaliana ; halophyte ; high-affinity potassium transporter (HKT) ; Na+ transporter ; salt tolerance ; Sporobolus virginicus ; aquaporins ; barley ; ion transport ; oocytes ; plasma membrane intrinsic proteins (PIPs) ; GmbZIP15 ; transcription factor ; drought stress ; soybean ; biotechnology breeding ; high-throughput sequencing ; QTLs ; rice ; halophytic wild barley ; salinity ; osmotic stress ; metabolome ; transcriptome ; ionome ; stress adaptation ; Hordeum marinum ; aquaporin ; Zygophyllum xanthoxylum ; plant growth ; abiotic stress ; sensing ; signaling ; transcription factors ; osmoregulation ; antioxidation ; ion homeostasis ; jasmonates ; jasmonate signaling pathway ; crosstalk ; exogenous jasmonate applications ; GWAS ; PGPR ; ACC deaminase ; seed priming ; IAA ; cell wall integrity ; cell wall sensor ; LRXs ; CrRLK1Ls ; Millettia pinnata ; calmodulin-like ; heterologous expression ; halophiles ; plant growth-promoting rhizobacteria (PGPR) ; RNA sequence analysis (RNA-seq) ; quantitative reverse transcriptase PCR (qRT-PCR) ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: In recent years, new and emerging digital technologies applied to food science have been gaining attention and increased interest from researchers and the food/beverage industries. In particular, those digital technologies that can be used throughout the food value chain are accurate, easy to implement, affordable, and user-friendly. Hence, this Special Issue (SI) is dedicated to novel technology based on sensor technology and machine/deep learning modeling strategies to implement artificial intelligence (AI) into food and beverage production and for consumer assessment. This SI published quality papers from researchers in Australia, New Zealand, the United States, Spain, and Mexico, including food and beverage products, such as grapes and wine, chocolate, honey, whiskey, avocado pulp, and a variety of other food products.
    Keywords: sensory ; physicochemical measurements ; artificial neural networks ; near infra-red spectroscopy ; wine quality ; machine learning modeling ; weather ; consumer acceptance prediction ; data fusion ; emotion recognition ; facial expression recognition ; galvanic skin response ; machine learning ; neural networks ; sensory analysis ; avocado ; cultivars ; preference mapping ; sensory evaluation ; sensory descriptive analysis ; consumer science ; unifloral honeys ; botanical origin ; physicochemical parameters ; classification ; natural language processing ; deep learning ; sensory science ; flavor lexicon ; long short-term memory ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Recombinant viruses expressing reporter fluorescent or bioluminescent proteins are an excellent option to evaluate the dynamics of viral infection progression in both cultured cells and/or validated animal models of viral infection. Reporter proteins are valid surrogates for direct detection of infected cells in vitro and in vivo, without the use of secondary methodologies to identify infected cells. By eliminating the need of secondary labeling, tractable replicating-competent, reporter-expressing viruses provide an ideal approach to monitor viral infections in real time, representing a significant advance in the study of the biology of viruses, to evaluate vaccination approaches, and to identify new therapeutics against viral infections using high-throughput screening settings. In this Special Issue “Replication-Competent Reporter-Expressing Viruses” we review replication-competent, reporter-expressing viruses belonging to different families, methods of characterization, and applications to facilitate the study of in vitro and in vivo viral infections. We also seek to discuss disadvantages and limitations associated with these reporter-expressing viruses. Finally, we provide rational future perspectives and additional avenues for the development, characterization, and applications of recombinant, reporter-expressing, competent viruses.
    Keywords: QH301-705.5 ; luminescence ; virus rescue approaches ; fluorescence ; Recombinant viruses ; plasmid-based reverse genetics ; reporter genes ; replicating-competent reporter-expressing viruses ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 24
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Introducing “A Feasible Approach for Natural Products to Treatment of Diseases”–an exploration of the therapeutic potential locked within nature’s abundant offerings. This comprehensive reprint delves into the fascinating realm of natural products, uncovering their inherent properties, mechanisms of action, and potential roles in effective disease management. Through extensive scientific research and reviews, the authors shed light on the immense potential of natural products as a viable approach to enhancing health and combating diseases. This reprint presents a diverse and multidimensional exploration, bridging the gap between traditional wisdom and contemporary scientific understanding and offering new avenues for healthcare professionals, researchers, and enthusiasts to harness the power of nature’s remarkable resources. As a catalyst for unlocking the healing potential of natural products, this reprint inspires further investigation and innovation, and drives us towards a future where their integration into mainstream healthcare becomes indispensable. Discover the possibilities and embark on a health and well-being journey with “A Feasible Approach for Natural Products to Treatment of Diseases”.
    Keywords: cancer immunotherapy ; fructan ; FT-IR ; mass spectrometry ; young green barley ; COVID-19 ; β-glucans ; immunomodulation ; anti-inflammation ; anti-oxidant ; ACE2 regulation ; impedance ; ECIS ; antitumor activity ; anticancer properties ; betulin ; betulinic acid ; Amadori rearrangement compounds ; barley ; anti-obesity ; arginyl-fructose ; adipogenic ; ergosta-5,7,22,24(28)-tetraenol (ERGT) ; cholesta-5,7,22,24-tetraenol (CHT) ; ergosterol biosynthesis ; antimetabolite ; suicide substrate ; Trypanosoma brucei ; coronavirus SARS-CoV-2 ; main protease ; Saussurea costus ; molecular docking ; GC-MS profiling ; Molineria recurvata ; diabetic nephropathy ; urinary biomarkers ; inflammation ; oxidative stress ; walnut ; Juglans regia ; high-fat diet ; insulin resistance ; cognitive function ; JNK/NFκB pathway ; Citri Reticulatae Pericarpium ; flavonoids ; anticancer ; mechanism ; phenotype ; Angelica sinensis polysaccharide ; Astragalus membranaceus polysaccharide ; hexokinase 2 ; glycolysis ; JAK2/STAT3 pathway ; liver regeneration ; Holoptelea integrifolia ; MMP-9 ; wound healing ; friedelin ; oxalactam A ; macrolactam ; anti-Rhizoctonia solani ; Penicillium oxalicum ; molecular dynamics ; non-alcoholic fatty liver disease (NAFLD) ; natural products ; terpenoids ; mechanisms ; treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: This reprint reviews a crop pest management use for several essential oils and the properties of an excellent lemon (citral) source. Research is reported on the biological properties of enhanced lemon oil along with the human intake of citrus beverages and the less common medicinal mastiha oil. Oils and hydrolates of rosemary and lavender were analyzed by headspace/GC-MS to better define their antibacterial, antioxidant and cytotoxic activities, and yeast particle encapsulation was investigated for the controlled release of bioactive terpenes.
    Keywords: monoterpenes ; mastiha oil ; absorption ; Citrus limon (L.) Osbeck ; essential oil ; citral ; nutraceuticals ; inflammation ; oxidative stress ; terpenes ; yeast particles ; antimicrobial ; anthelmintic ; prodrug ; beverages ; Citrus ; coumarins ; furocoumarins ; polymethoxyflavones ; linear retention indices ; liquid chromatography ; tandem mass spectrometry ; multiple reaction monitoring ; quality control ; Backhousia citriodora ; lemon myrtle ; lemon oils ; geranial ; neral ; iso-citrals ; citronellal ; flavor ; fragrance ; biological activity ; Lavandula angustifolia ; Rosmarinus officinalis ; essential oils ; hydrolates ; chemical analysis ; volatile compounds ; phytochemicals ; synergism ; fractional inhibitory concentration ; insect mortality rate ; phytopathogenic fungi ; insect pests ; pesticide resistance ; fungicide resistance ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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  • 26
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: This book is relevant to architects, urban designers, planners, and policy makers concerned with enhancing climate-sensitive urban form and planning. It discusses building and neighborhood design: layout and design features that maximize energy efficiency and thermal comfort without compromising the ability of other buildings to enjoy similar benefits; the use of interstitial spaces (piazzas, streets, and parks) to improve the microclimate at the neighbourhood-level; design intervention case studies; innovative uses of interstitial spaces to improve the local climate at the neighborhood level; and urban radiative cooling solutions to mitigate the unintended climate consequences of urban growth and suggestions for ways forward.
    Keywords: cooling effect ; urban park ; thermal comfort ; physiological equivalent temperature ; perceived thermal comfort ; urban heat island ; air temperature ; sustainable cities ; smart cities ; urban health ; global warming ; urban green spaces ; sustainable urban development ; climate change mitigation and adaptation ; urban resilience  ; heatwaves ; urban overheating ; urban heat island intensity ; energy budget equation ; sensible heat flux ; latent heat flux ; advective heat flux ; Australian climatic conditions ; coastal cities ; desert climate ; surface urban heat island effect ; land use/land cover ; partial least square regression ; nonlinear programming ; Shanghai ; China ; urban form ; urban microclimate design ; city ; sustainability ; sustainable development ; cool roof ; passive radiative cooling ; metamaterials ; prototype ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHH Thermodynamics & heat
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  • 27
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Several epidemiological studies have demonstrated that oxidative stress is associated with a number of health disorders, including cardiovascular malfunction, certain types of cancer, diabetes mellitus, many other auto-immune diseases, and even ageing. The body possesses multiple mechanisms to counteract oxidative stress, which employ antioxidant compounds that are either naturally generated in situ (endogenous antioxidants) or externally supplied through food (exogenous antioxidants). These antioxidants are able to counteract oxidative stress, thanks to their ability to neutralize excess free radicals and protect the cellular lipids, proteins, and DNA from molecular damage. Exogenous antioxidants from the diet are of increasing interest because of their beneficial role in maintaining good health and in preventing chronic diseases. Indeed, a diet rich in dietary antioxidants, especially from fruits and vegetables, has been correlated with a successful prevention and lower incidence of several degenerative pathologies, including obesity, diabetes, cardiovascular diseases, and cancer. This Special Issue of Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature, examining the role of diets rich in antioxidant compounds in the prevention of chronic diseases and the characteristics of the antioxidants included in such diets.
    Keywords: QH301-705.5 ; antioxidants ; chronic diseases ; dietary supplementation ; human health ; prevention ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: This Special Issue contains one review and five original articles, all of which address cutting-edge research in the field of water and environmental virology. The review article by Gerba and Betancourt summarizes the current status and future needs for the development of virus detection methods in water reuse systems, especially focusing on methods to assess the infectivity of enteric viruses. Original papers cover a variety of research topics, such as an environmental monitoring survey of group A rotaviruses in sewage and oysters in Japan, the occurrence and genetic diversity of noroviruses and rotaviruses in a wastewater reclamation system in China, the detection of viruses and their indicators in tanker water and its sources in Nepal, integrated culture next-generation sequencing to identify the diversity of F-specific RNA coliphages in wastewater, and the development of a portable collection and detection method for viruses from ambient air and its application to a wastewater treatment plant.
    Keywords: Q1-390 ; reuse ; aerosols ; viral indicator ; wastewater treatment ; microbial contamination ; index virus ; real-time PCR ; tanker water ; virus ; wastewater reclamation ; pathogenic virus ; infectivity ; chlorination ; molecular methods ; wastewater ; next-generation sequencing ; fecal source tracking ; oyster ; fecal-source marker ; viral contamination ; cell culture ; pathogenic microorganisms ; rotavirus ; ultraviolet disinfection ; F-specific RNA bacteriophage strain ; sewage ; waterborne gastroenteritis viruses ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 29
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Diet and nutrition are key tools in promoting health and reducing the comorbidities of chronic diseases. There are thousands of biomolecules in fruits, vegetables, wild and medicinal plants, other land and marine organisms, which can exert functional and health-promoting effects through bioactivity beyond nutrition. From the enormous amount of knowledge generated from different natural bioactive ingredients present in foods, we are aiming to bring together experts working in different fields of food, nutrition, and health, in order to work on this Special Issue, with a comprehensive collection of papers to gain insight into the most promising bioactive compounds in different foods, to improve the preservation of bioactivity during the food processing chain, and to provide scientific evidence of the efficacy of key bioactives in foods in preventing disease and improving health and wellbeing.
    Keywords: QH301-705.5 ; TX341-641 ; Health ; Bioactives ; Nutrition and Metabolism ; Nutrients ; Bioavailability ; Food ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 30
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: This reprint is devoted to “greener catalysis for environmental applications”, and primarily covers the catalytic synthesis of value-added chemicals, as well as the catalytic removal of pollutants. The most important topics covered were the conversion of waste to the product, solvent-free conditions as well as toxicity assessment of the reaction products.
    Keywords: selectivity tuning ; CO2 methanation ; reverse water gas shift ; photocatalysis ; dye ; UV ; peroxydisulfate ; advanced oxidation process ; Fischer-Tropsch ; jet fuel ; gasoline ; CoMn ; hydrotalcite-like precursors ; heterogeneous catalysis ; montmorillonite ; benzimidazoles ; gallium ; vanadium ; hydrodesulfurization ; hydrogenation ; synthesis method ; catalysis ; zero valent iron ; de-chlorination ; borohydride ; sol-gel ; ferromagnetic ; glycine–nitrate process ; copper-based nanoparticles ; photocatalysis activity ; NP9EO ; Fenton degradation ; ofloxacin ; Fe3O4 ; zeolite ; heterogeneous ; ion exchange resins ; waste cooking oil ; reuse of catalyst ; epoxidation ; Circular Economy ; contaminants of emerging concern ; advanced oxidation processes ; by-products ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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  • 31
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: Vegetable crops provide valuable minerals and vitamins that are indispensible for human health. Scientists have been working on the genetics of vegetable crops, deciphering the molecular bases of agronomically important traits. These genetic bases and variations in vegetable traits will greatly facilitate vegetable genetic improvement. Therefore, the genes of and genetic research on vegetable crops are of great importance. This Special Issue is a collection of 13 important research papers addressing the genes, genetics, and breeding of major vegetable crops. In the present book, the authors described the genes and QTLs responsible for stress tolerance, disease resistance, vegetable yield, and quality. The 13 research papers cover germplasm enhancement and evaluation, QTL mapping, gene isolation, marker development, and gene expression as well as gene editing in a wide range of vegetable species, including broccoli, pepper, eggplant, onion, and Cucurbita species. Readers from all over the globe are expected to greatly benefit from this Special Issue collection regarding their own work and the goal of improving breeding efficiency with molecular breeding to generate environment-adaptive, high-yield, and high-quality vegetable crops with which to feed the global population of 9.7 billion in an extreme climate by 2050.
    Keywords: pepper ; Capsicum annuum ; Phytophthora capsici ; high-density genetic map ; QTL ; Capcicum annuum L. ; RNA-Seq ; nitrogen-use efficiency ; low-nitrogen tolerance ; CaHSP18.1a ; gene silencing ; transgenic Arabidopsis ; heat stress ; gene expression ; pumpkin ; simple sequence repeat (SSR) ; syntenic relationship ; cross-species markers ; population structure ; eggplant ; heat shock factor (Hsf) ; heat shock protein (Hsp) ; thermotolerance ; C. frutescens ; SSR ; germplasm ; genetic diversity ; CRISPR/Cas ; gene knockout ; genome editing ; germplasm resource ; precision editing ; regulatory framework ; trait improvement ; Brassica oleracea ; broccoli ; candidate gene ; anthocyanin ; allelochemicals ; VOCs properties ; VOCs action ; VOCs detection ; green agriculture ; progress ; genetic researches ; molecular breeding ; transcriptomics ; transcription factor ; heritability ; genetic advance ; multi-trait selection ; principal component analysis ; HRM ; molecular marker ; phylogenetic analysis ; RNA sequencing ; SCAR ; SNP ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The diversity of wood and non-wood forest products is enormous and reflected in their anatomical, physical and chemical properties as well as their potential applications. Special attention should be given to lesser-known species and even to invasive species, which may be profitable when properly managed, thereby decreasing the overexploitation of threatened species. Besides the market importance of stem wood, other tree components and non-wood forest products, often regarded simply as forest residual materials, are valuable forest resources with various potential applications that can strengthen the circular economy. Assessing the characteristics of these diverse materials, such as their structure and anatomy as well as their physical and chemical properties, is fundamental for evaluating their potential and increasing high-quality end-uses. This knowledge will also contribute to sustainable forest management with enhanced forest diversity and species conservation in addition to the reinforcement of certification and environmental policies.
    Keywords: Calamus zollingeri ; Calamus ornatus ; dynamic vapor sorption ; basic density ; volumetric swelling ; white rot ; mold ; Quercus suber L. ; seasonal variation ; cuticular waxes ; leaves ; new species ; morphology ; wood ; properties ; chemical composition ; spectroscopy ; chemometrics ; unconventional species ; Quercus suber ; cork borer ; cork ; phenolics ; tropical species ; wood anatomy ; wood density ; wood color ; multivariate analysis ; species diversity ; dark-brown zone ; lenticular filling tissue ; quantitative anatomical characteristics ; Quercus variabilis ; reproduction cork ; scanning electron microscopy ; sclereid ; virgin cork ; Cytisus scoparius ; liquefied ; optimization ; eco-valorization ; agro-industrial residues ; Asparagaceae ; lignocellulose ; crystalline cellulose ; syringyl/guaiacyl ; anatomy ; Tilia amurensis Rupr. ; Tilia mandshurica Rupr. & Maxim. ; branch ; wood properties ; papermaking material ; tropical timber ; color parameters ; mid-infrared spectroscopy ; FTIR ratios ; environmental factors ; West African Sahel ; Cupressus funebris Endl. wood ; wood knots ; physical properties ; wood color properties ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: New scientific advances in different areas have allowed the design of more precise strategies for the prevention and treatment of metabolic disorders through nutrition. In this context emerges the term Precision Nutrition, a new approach that takes advantage of scientific knowledge about the interaction of internal and external environmental factors to develop dynamic and precise nutritional recommendations. Therefore, Precision Nutrition includes personalized advice based on genetics and well-documented gene–nutrient–phenotype interactions, as well as other factors such as individual metabolome, transcriptome, and microbiota profile; food behavior; and dietary, physical activity, and life-style habits; and the resulting interactomes. Precision Nutrition should be based at least on three sequential steps: conventional nutritional approaches (considering age, gender, and physiological states); the incorporation of nutritional and health status information (e.g., metabolites, physical and nutritional behavior); and the genetic baggage including multiomics functional integration.
    Keywords: dietary parameters ; carbohydrate intake ; obesity ; single nucleotide polymorphism ; CLOCK gene ; rs3749474 ; sodium intake ; hypertension ; single-nucleotide polymorphism ; personalized nutrition ; dietary vitamin A ; body fat ; UCP ; retinoic acid ; PBMC ; genetic variant ; weight loss ; nutrigenomics ; dietary intervention ; FTO gene ; dietary protein ; dietary carbohydrates ; dietary fat ; macronutrients ; gene-diet interaction ; glucose homeostasis ; glaucoma ; polygenetic-risk scores ; gene-gene interaction ; gene-nutrient interaction ; precision medicine ; childhood ; insulin resistance ; adipokine ; metabolomics ; biomarkers ; ELOVL ; metabolic alterations ; Mexican population ; Single Nucleotide Polymorphisms ; pediatrics ; cardiometabolic risk factors ; precision nutrition ; eating behavior ; nutrigenetics ; microbiota ; metabolic syndrome ; Mediterranean diet ; genetic risk score ; HELENA ; adolescents ; sex ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: Metal 3D printing, as an advanced forming, can manufacture parts directly from digital model by using layer by layer material build-up approach. This manufacturing method can prepare complex shape metal parts in short time, with and high precision. Three-dimensional printing processes can be classified into two major groups: Powder Bed Fusion-based technologies and Directed Energy Deposition. Three-dimensional printing features freedom of part complexity, part design, and light-weighting for aerospace, automobile, and other industries application. The Global Metal 3D Printing Market is mainly driven by the the fast developing of aerospace and automobile industry. The Global Metal 3D Printing Market size was valued at USD 534.18 Million in 2020 and is projected to reach USD 4458.76 Million by 2028, growing at a CAGR of 30.38% from 2021 to 2028.
    Keywords: 17-4PH ; SLM ; solution temperature ; microstructure and properties ; selective laser melting ; CuCrZr alloy ; process parameters ; relative density ; tensile properties ; Ni-based superalloys ; electron beam melting ; additive manufacturing ; Argon gas atomized ; plasma rotation electrode process ; powder characteristics ; residual stresses ; selective laser melting (SLM) ; finite element modeling (FEM) ; triply periodic minimal surface (TPMS) ; copper corrosion ; liquefied petroleum gas ; H2S corrosion ; SEM ; XPS ; CLF-1 steel ; microstructure ; mechanical properties ; in-situ alloying ; composition inhomogeneity ; computer simulation ; processing map ; laser powder bed fusion ; graphene ; high temperature ; mechanical property ; alumina ; cobalt-chromium-molybdenum alloy ; electroless plating ; friction performance ; implants ; Laser Powder Bed Fusion ; defects ; process parameter ; powder bed fusion ; surface roughness ; porosity ; residual stress ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Keywords: 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: The practical importance of economic valuation information can hardly be overstated. Coastal and marine resource policy planning and management benefit from complete information on the impact of policy decisions.
    Keywords: Q1-390 ; internet survey ; open access ; contingent valuation method ; coastal management ; tourism ; Thailand ; marine ; wetlands ; harmful algae blooms ; environmental valuation ; quota ; cyanobacteria ; estuarine and coastal ecosystems ; wealth accounting ; seawater quality ; economic analysis ; remote sensing ; ecosystem restoration ; coastal ecosystems ; random utility model ; contingent behavior ; public policy ; habitat–fishery linkages ; Barbados ; coastal ecosystem services valuation ; fishery ; mangroves ; ecosystem services valuation ; coral reefs valuation ; recreational boating ; regulated open access ; non-market value ; economic valuation ; ecosystem services ; coastal ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Keywords: QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 39
    Publication Date: 2024-04-05
    Description: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-08-12
    Description: Silica and silicon-based nanostructures are now well-understood materials for which the technologies are mature. The most obvious applications, such as electronic devices, have been widely explored over the last two decades. The aim of this Special Issue is to bring together the state of the art in the field and to enable the emergence of new ideas and concepts for silicon and silica-based nanostructures.
    Keywords: maize ; NPK ; SiO2-NPs ; productivity ; fertilizer ; mineral ; weevils ; LC50 ; toxicity ; mesoporous silica ; nanomaterials ; desulfurization ; fuel ; JP-8 ; black silicon ; light absorption enhanced ; micro-nano manufacturing ; nanometer surface ; nano-silica ; tricalcium aluminate ; pozzolanic reaction ; C-A-S-H gel ; silicon nanoparticles ; silicon nanowires ; synthesis ; high energy density ; lithium-ion batteries ; high-capacity anode ; VLS ; laser pyrolysis ; size effect ; shape effect ; biomass rice husk ; silicon ; nanocrystals ; luminescence ; high porosity ; pH sensor ; temperature sensor ; dual sensor ; metal-assisted chemical etching ; Si nanostructures ; high aspect ratio ; zone plate ; silicon nanowire ; nanowire array ; silicon anode ; n-type silicon anode ; Li-ion battery ; nanowires ; nanonets ; transistor ; integration process ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-11-17
    Description: This Special Issue provides a collection of recent research and reviews that investigate many areas of welfare assessment, such as novel approaches and technologies used to evaluate the welfare of farmed, captive, or wild animals. Research in this Special Issue includes welfare assessment related to pilot whales, finishing pigs, commercial turkey flocks, and dairy goats; the use of sensors or wearable technologies, such as heart rate monitors to assess sleep in dairy cows, ear tag sensors, and machine learning to assess commercial pig behaviour; non-invasive measures, such as video monitoring of behaviour, computer vision to analyse video footage of red foxes, remote camera traps of free-roaming wild horses, infrared thermography of effort and sport recovery in sport horses; telomere length and regulatory genes as novel biomarkers of stress in broiler chickens; the effect of environment on growth physiology and behaviour of laboratory rare minnows and housing system on anxiety, stress, fear, and immune function of laying hens; and discussions of natural behaviour in farm animal welfare and maintaining health, welfare, and productivity of commercial pig herds.
    Keywords: bioethics ; domestication ; genetic selection ; animal behavior ; animal welfare ; eye caruncle temperature ; Spanish Sport Horse ; performance test ; genetic lines ; heritability ; infrared thermography ; pigs ; welfare ; health ; herd management ; monitoring technologies ; animal husbandry ; welfare assessment ; wellbeing ; goat ; caprine ; dairy ; dairy cows ; heart rate ; sleep ; heart rate variability ; polysomnography ; animal-based welfare indicators ; camera traps ; wild horses ; precision swine farming ; ear tag pig sensor ; behavioral monitoring ; machine intelligence ; technology adoption ; broiler ; corticosterone ; performance ; telomeres ; telomere regulators ; stress biomarkers ; horse ; equine ; lying ; time budget ; locomotion ; geriatric ; orthopedic ; recumbency ; mixed commercial turkey flocks ; on-farm assessment ; YOLOv4 ; computer vision ; animal monitoring ; animal activity ; body posture ; rare minnow ; environmental enrichment ; growth ; physiology ; anxiety-like behavior ; enrichment ; hospitalization requirement ; lameness ; lesions ; tail biting ; attention bias ; conventional cage ; environmental complexity ; feather corticosterone ; IgA ; laying hen ; animal welfare assessment ; behaviour ; human intervention ; marine mammal ; cetacean ; management ; stranding ; wildlife ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The intention of this Special Issue is to focus on new aspects of drug discovery, including the search for new molecular targets of various diseases, the creation of new modern methods for diagnosing diseases, the development of new test systems and kits for assessing the selectivity and effectiveness of new drugs, the study of the molecular mechanisms of biologically active compounds, the formulation of new drugs, pharmacokinetic and pharmacodynamic studies, and preclinical trials of important molecules.
    Keywords: Streptococci ; antimicrobials ; QSAR ; MD simulation ; Kunitz-type peptides ; neuroprotective activity ; sea anemones ; TRPV1 ; P2X7R ; Parkinson’s disease (PD) ; diffuse large B cell lymphoma (DLBCL) ; deep neural network ; drug discovery ; drug combination ; biomarker ; cancer severity ; cancer prognosis ; MAFB ; tumor-associated macrophages ; prostate cancer ; photodynamic therapy ; magnetic resonance imaging ; ex vivo ; anti-inflammatory substance ; N-acylhydrazone ; naphthyl-N-acylhydrazone ; LASSBio-1524 analogues ; phosphacoumarin ; azomethine ylide ; cycloaddition ; anti-cancer ; cytotoxicity ; quantum chemistry ; pravastatin ; metformin ; radiation-induced intestinal injury ; minipigs ; epithelial regeneration ; inflammation ; arylazo sulfones ; DNA binding ; DNA cleavage ; DNA photocleavage ; A375 melanoma cells ; molecular docking ; radicals ; N–S bond homolysis ; platinum(II) ; five-coordinate complexes ; glycoconjugation ; cytotoxic activity ; protein X-ray structure ; lipophilicity ; natural products ; acetylcholinesterase inhibitors ; butyrylcholinesterase inhibitors ; Alzheimer’s disease ; central nervous system ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The Special Issue aimed to bring together scientists working in various branches of control theory to discuss manufacturing control problems that include the following: enterprise control and digital ecosystem creation; the development of identification theory and methodology, and related mathematical problems; parameter, nonparametric, and structure identification and expert analysis; problems regarding selection and data analysis; control systems with an identifier; modeling in intelligent systems; simulation procedures and software; digital identification; reinforcement learning; quantum modeling; intelligent model predictive control; predictive cognitive issues; problems with software quality for complex systems; and global network resources for support processes of modeling and control.
    Keywords: decision-making ; psychic and behavioral components of activity ; action ; result of activity ; equilibrium stability ; consensus ; threshold behavior ; cognitive dissonance ; conformity ; informational control ; informational confrontation ; soft sensing ; multivariate filter ; reactive distillation ; optimal stochastic control ; path planning ; 2D random search ; interception ; external disturbances ; invariance ; block control principle ; decomposition ; high-gain factors ; sliding mode control ; sigmoid function ; Gramian method ; bilinear system process identification ; generalized Lyapunov equation ; knowledgebase ; associative search models ; wavelet analysis ; adaptive differential evolution ; evolutionary computing ; Hammerstein ; nonlinear system identification ; bilinear systems ; eigenmode decomposition ; spectral expansions ; Gramians ; observability ; controllability ; small-signal analysis ; numerical algorithm ; tokamak ; plasma equilibrium reconstruction ; linear plasma models ; identification ; state observer ; LMI ; least square technique ; deep neural network ; parametric uncertainty ; robust control ; super-stability ; regular form ; dynamic mode decomposition ; system identification ; Runge–Kutta method ; nonparametric model ; artificial neural network ; Izhikevich artificial neuron ; vestibular–ocular reflex ; control Lyapunov function ; Bayes criterion ; Haar wavelets ; loss function ; mean risk ; observable stochastic systems (OStS) ; stochastic process (StP) ; wavelet canonical expansion (WLCE) ; nonparametric identification ; dynamic system ; integral model ; Volterra equations ; smoothing cubic splines ; selection of the smoothing option ; modeling ; regularization ; inverse problems ; balanced identification ; error analysis ; one-dimensional heat equation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
    Keywords: QH301-705.5 ; Q1-390 ; glutamic acid ; n/a ; direct mass spectrometry ; neurodegeneration ; 6-OHDA ; targeted mass spectrometry ; mitochondrial dysfunction ; myo-inositol ; metabolomics ; bile acids ; subacute mild traumatic brain injury ; age-related macular degeneration ; metabolic pathways ; energy metabolism ; midbrain ; Alzheimer’s disease ; biomarkers ; 1H NMR ; Parkinson’s disease dementia ; GC-MS ; pathogenesis ; tricarboxylic acid cycle ; micro-dialysis ; 13C-labeled succinate ; metabolism ; lipidomics ; dementia with Lewy bodies ; fatty acid ; prodromal Parkinson’s disease ; malonate ; cerebral ischemia ; mass spectrometry ; retinal pigment epithelium ; excitotoxicity ; endothelin-1 ; reperfusion ; C. elegans ; Streptomyces venezuelae ; ?-synuclein aggregates ; natural product ; fatty acid metabolism ; imaging mass spectrometry ; LC-MS ; drusen ; cerebral palsy ; plasma ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
    Keywords: QH301-705.5 ; SF1-1100 ; Q1-390 ; n/a ; muscle texture ; fractal analysis ; fish welfare ; Danio rerio ; motivation ; histopathology ; elevated phosphate concentrations ; sharks ; welfare ; African catfish (Clarias gariepinus) ; feed efficiency ; fighting ability ; aggressive interaction ; social rank ; boldness ; ethology ; fisheries management ; physiological response ; FishEthoBase ; welfare scores ; welfare criteria ; stress ; pain ; stereotypical behaviour ; Scyliorhinus canicula ; animal behavior ; welfare enhancement ; social communication ; nociception ; negative and positive affect ; aggression ; fertilisation success ; risk analysis ; aquaculture ; hematology ; Amyloodinium ocellatum ; framework ; structural complexity ; territorial ; growth ; positive welfare ; social stress ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The re-use of industrial food residues is essential in the general framework of rational waste handling and recycling, which aims at the minimizing environmental impact of food production and producing functional food ingredients. Agri-food processing waste has long been considered a valuable biomass with a significant polyphenol load and profile. Polyphenols, aside from being powerful antioxidants that confer inherent stability to a variety of foods, may possess versatile bioactivities including anti-inflammatory and chemopreventive properties. The valorization of agri-food waste as a prominent source of polyphenols stems from the enormous amount of food-related material discharged worldwide and the emerging eco-friendly technologies that allow high recovery, recycling, and sustainable use of these materials. This book addresses the concept of recovering natural polyphenolic antioxidants from waste biomass generated by agri-food and related industrial processes and presents state-of-the-art applications with prospect in the food, cosmetic, and pharmaceutical industries.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; valorization ; ultrasound assisted extraction ; microwave assisted extraction ; Box–Behnken design ; HPLC-DAD-q-TOF-MS ; Dioscorea batatas ; green oleo-extraction ; grape marc ; quantitative analysis ; natural antioxidants and flavors ; antioxidant ; infrared-assisted extraction ; anti-ageing ; anthocyanins ; liquid chromatography-mass spectrometry ; Chinese yam ; functional food ; extraction ; olive mill wastewater ; adsorbents ; relative solubility simulation ; HPLC-fluorometric detector (FLD)–MS ; saffron ; antioxidants ; food-grade solvents ; Mango ; zero-waste biorefinery ; response surface methodology ; ophthalmic hydrogel ; olive leaves ; sonotrode ultrasonic-assisted extraction ; vegetable oils and derivatives ; anti-inflammatory ; skin whitening ; phenolics ; Brewers’ spent grains ; proanthocyanidins ; brewer’s spent grain ; anti-inflammatory and antioxidant activity ; antimicrobial activity ; by-products ; antiplatelet activity ; phenanthrenes ; wine lees ; bioactive compounds ; deep eutectic solvents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: Radiopharmaceuticals are used in the diagnosis and treatment of various diseases, especially cancer. In general, radiopharmaceuticals are either salts of radionuclides or radionuclides bound to biologically active molecules, drugs, or cells. Tremendous progress has been made in discovering, developing, and commercializing numerous radiopharmaceuticals for the imaging and therapy of cancer. Significant research is ongoing in academia and the pharmaceutical industry to develop more novel radiolabeled compounds as potential radiopharmaceuticals for unmet needs. This Special Issue aims to focus on all aspects of the design, characterization, evaluation, and development of novel radiolabeled compounds for the diagnosis and treatment of cancer and the application of new radiochemistry and methodologies for the development of novel radiolabeled compounds. Outstanding contributions presented in this Special Issue will significantly add to the field of radiopharmaceuticals.
    Keywords: positron emission tomography (PET) ; pyrazoles ; fluorine-18 ; radionuclides ; PET probes ; imaging pharmaceuticals ; hypopharyngeal cancer ; 188Re-liposome ; repeated therapy ; NGS ; microRNA ; aprepitant ; radiopharmaceuticals ; neurokinin 1 receptor antagonist ; radionuclide chelators ; kidney uptake ; cleavable linkers ; neutral endopeptidase (NEP) ; renal brush border enzymes ; prostate-specific membrane antigen (PSMA) ; cancer imaging and therapy ; somatostatin analogs ; radiolabeling ; radionuclide therapy ; imaging ; adrenergic receptor ; positron emission tomography ; radiotracer ; cholecystokinin-2 receptor ; minigastrin ; molecular imaging ; targeted radiotherapy ; lutetium-177 ; EpCAM ; radionuclide ; SPECT ; iodine ; PIB ; breast ; cancer ; PET ; target-specific biomolecules ; immunoPET imaging pharmaceuticals ; production processes ; 124I-labeled monoclonal antibodies ; radiotracers ; AAZTA ; scandium-44 ; FAP ; SA ; DPP ; PREP ; radioiodine labeling ; radioiodination ; biomolecules ; peptides ; proteins ; monoclonal antibodies ; 123,124,125,131I-labeled molecules and biomolecules ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: A collection of 18 scientific papers written in honor of Professor Karlheinz Schwarz's 80th birthday. The main topics include spectroscopy, excited states, DFT developments, results analysis, solid states, and surfaces.
    Keywords: density functional theory ; Coulomb systems ; excited states ; nodal variational principle ; DFT ; anatase TiO2(101) surface ; adsorption energy ; Bader charge ; helium atom ; screened Coulomb potential ; variational Monte Carlo method ; Lagrange mesh method ; comparison theorem ; TD-DFT ; MC-PDFT ; Lie–Clementi ; Colle–Salvetti ; OLEDs ; subphthalocyanines ; UV–visible spectra ; axial substituents ; peripheral substituents ; time-dependent DFT ; hexatetra-carbon ; electrical properties ; molecular aggregates ; singlet excitons ; triplet excitons ; TDDFT ; charge-transfer states ; charge-resonance states ; Frenkel states ; localized excitations ; diabatic states ; adiabatic states ; semiconductors ; oscillator strength ; hybrid exchange-correlation functional ; non-local potential ; statistics ; methods comparison ; benchmarking ; band gaps ; atomization energy ; DFT codes ; electronic structure calculation ; numerical accuracy and precision ; kinetic functional ; Yukawa potential ; periodic DFTB ; deMonNano ; graphene ; graphite ; benzene dimers ; deposited benzene ; supported clusters ; weighted mulliken charges ; LAPW method ; APW+lo method ; all-electron DFT ; density matrix functional embedding ; density-functional theory ; householder transformation ; He atomic basis sets ; helium dimer ; He2 potential well ; correlation energy ; complete basis set ; sigma basis set ; atomic multiplet theory ; crystal/ligand-field theory ; coordination compounds ; electronic structure ; Cu2OCl2 ; Cu2OBr2 ; Cu2OI2 ; oxyhalides ; magnetic couplings ; Néel temperature ; chemical pressure ; NMR ; machine learning ; zeolites ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNR Physical chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: This Special Issue collects original research articles discussing cutting-edge work as well as perspectives on future directions in the whole range of theoretical and practical aspects in these research areas: i) Theory of fuzzy systems and soft computing; ii) Learning procedures; iii) Decision-making applications employing fuzzy logic and soft computing.
    Keywords: fuzzy partition ; fuzzy transform ; new iterative method ; Cauchy problems ; ANFIS ; basmati rice ; image processing ; grading ; quality assessment ; fuzzy inference system ; causality ; statistics ; concept-mapping ; causal graph ; numerical methods ; systems of ordinary differential equations ; NIM ; fuzzy logics ; linear motion blur ; fuzzy deblurring ; electron beam calibration ; signal and image processing ; propagation modeling ; adaptive-network-based fuzzy system ; LoRa &amp ; LoRaWAN ; radio wave propagation ; artificial neural networks ; subtracting clustering ; dual double fuzzy semi-metric ; double fuzzy semi-metric ; fuzzy semi-metric space ; triangle inequality ; triangular norm ; eye gaze tracking ; interval type-2 fuzzy logic ; vision system ; mobile robots ; intelligent control ; ordered fuzzy number ; fuzzy relation ; preorder ; strict order ; equivalence relation ; variable neighborhood search ; experimental comparison ; statistical analysis ; traveling salesman problem ; soft computing ; modeling ; vector optimization ; methods of solution of vector problems ; optimal decision-making ; numerical realization of decision-making ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Ice crystals are the most ubiquitous material found in the cryosphere environment of the Earth, in the planetary system, and also in our daily lives. In recent years, ice crystals have increased in importance as one of the key materials for finding solutions to settle various environmental concerns at a global scale. Furthermore, ice crystals are unique materials which are potentially extremely useful in various applications, for example, within the food sciences, medical sciences, and other fields. In dealing with these interesting subjects, research on ice crystals has been more actively pursued in recent years. The Special Issue “Ice Crystals” presents a wide varieties of topics related to ice crystals. It can be considered as a status report reviewing the recent research on ice crystals and serves to provide readers with information on the latest developments concerning ice crystals.
    Keywords: Q1-390 ; QC1-999 ; coarsening kinetics ; antifreeze protein ; microstructure ; ice crystals ; decomposition ; formation ; cryo-photo microscopy ; cryoprotective agent ; ice cream ; reformation ; tomography ; deformation ; clathrate hydrate ; Negative thermal expansivity ; tetrahydrofuran ; ice crystal ; pressure ; molecular dynamics ; Grüneisen parameter ; modelling ; ab initio calculation ; freezing ; nanoscale pores ; quasi-liquid layer ; electron paramagnetic resonance ; potential of mean force ; gas hydrate ; spin labeling ; pre-decomposition pressure ; mW model ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 51
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Thanks to their rich chemodiversity, marine natural products represent a unique source of new bioactive metabolites. As the new leading compounds in drug discovery and development, these molecules may represent challenges for the treatment of a number of human diseases, attracting the attention of many researchers during their chemical and biological studies. This Special Issue covers all fields of drugs research in which marine natural products are involved, including their isolation and characterization, biological activities, and medicinal applications as well as synthetic approaches and their related analogues. The cover picture shows “The Nudibranch mollusk Godiva quadricolor on a sponge, reflected under the surface during the low tide. Fusaro Lagoon, Bacoli (Naples)”.
    Keywords: alginate ; Sargassum duplicatum ; okra ; antioxidant ; diabetic ; wound healing ; sulfavant ; sulfoquinovosyldiacylglycerols ; sulfoglycolipids ; mass spectrometry ; UHPLC-MS ; lipids ; cancer therapy ; gold nanoparticles ; marine products ; natural products ; photosensitizer ; purpurin 18 ; reactive oxygen species ; seaweed ; biosilica ; diatom frustule ; sustainable production ; drug delivery ; Sargassum ilicifolium ; mangosteen rind ; diabetic mice ; Aquimarina sp. ; diketopiperazine ; N-phenethylacetamide ; epithelial-mesenchymal transition (EMT) ; A549 cells ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 52
    Publication Date: 2023-04-05
    Description: This reprint includes papers from different research fields, reflecting the sectional talks presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, which took place in June 2021. The objective of the 2021 Conference was to bring together perspectives and challenges in doctoral research in a common forum and to provide a platform enabling doctoral researchers to meet and share state-of-the-art developments in their fields. It consists of 16 papers presented at the 9th edition of the Scientific Conference of the Doctoral Schools from the “Dunărea de Jos” University of Galaţi, in several fields such as: mechanical and industrial engineering, food science and biotechnology, electrical/electronic engineering, systems engineering and information technologies, chemistry, electrochemistry, and economic models and strategies.
    Keywords: incremental pumps ; profiling of generating tools ; helical surfaces ; Romania ; coastal area ; wind energy ; measurements ; IEC classes ; wind turbines ; mass tourism ; management model ; Constanta ; PESTEL ; Black Sea ; sustainability ; eggplant peels ; bioactive compounds ; hydrogels ; anthocyanins ; beetroot peel ; betalains ; polyphenols ; CCD-RSM ; optimal control ; metaheuristic algorithms ; evolutionary algorithms ; simulation ; ventilation on ships ; HVAC requirements ; COVID-19 ; spread the disease ; airborne transmission ; HEPA filtration ; UV disinfection ; heat recovery ; L-tryptophan ; polypyrrole ; sensor ; amino acid ; cyclic voltammetry ; chronoamperometry ; atorvastatin ; carbon nanotubes ; gold nanoparticles ; Hippophae rhamnoides L. ; carotenoids ; flavonoids ; antioxidant activity ; microencapsulation ; modulation ; electromagnetic disturbances ; electromagnetic compatibility ; military ship ; communication systems ; navigation conditions ; Danube River ; management tool ; quality function deployment ; house of quality ; enwrapping surfaces ; profiling ; geometrical methods ; tower ; wind turbine ; load ; offshore wind ; marine renewable energy ; living labs ; design thinking ; coastal zone ; integrated coastal zone management (ICZM) ; Romanian coastal zone ; Black Sea basin ; wind parameters ; historical data ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCM Development economics & emerging economies
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Mycotoxins are secondary metabolites produced by molds. Although the primary role of these toxins is thought to be related to the colonisation of the environment by the fungi—mycotoxins are able to kill other micro-organisms (antimicrobial effect) and/or plant cells (mycotoxin-producing fungi being necrophagic)—the exposure of animals and humans to mycotoxins through the consumption of mycotoxin-contaminated food and feeds leads to diseases and death. Among the different mycotoxins described (more than 350 mycotoxins have been identified), deoxynivalenol (DON or vomitoxin) produced by Fusarium species has attracted the most attention due to its prevalence and toxicity. DON is part of a family of mycotoxins called trichothecenes that are small sesquiterpenoids with an epoxide group at positions 12–13 allowing their binding to ribosomes causing the so-called ribosome stress response, characterized by the activation of various protein kinases that lead to alterations in gene expression and cellular toxicity in animals, humans and plants. Here, we compiled very recent findings regarding DON and its derivatives: i) their prevalence in human food; ii) the estimation of the exposure of humans to them using biological markers; iii) their roles during plant–fungi interaction; iv) the alteration caused by them in animals and humans, particularly at low doses that are close to those observed in farm animals and human consumers; v) possible strategies to decrease their presence in food and feeds. Overall, this book will give the reader a clear and global view on this important mycotoxin produced by Fusarium species which is responsible for huge economic loss and health issues.
    Keywords: QH301-705.5 ; cell entry ; deoxynivalenol ; DON derivative ; cell effect ; trichothecene ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Fire regimes (occurrence, cycle, severity, size, etc.) are key factors in many forest ecosystems, as they are often critical drivers of forest composition, dynamics, and ecosystem processes. Fire regimes vary in space and time according to climatic, physical and biological factors. A better understanding of the interacting factors controlling fire regimes may contribute to improving fire and forest management and their future projection in the context of global change. Knowledge of how fire regimes affect natural landscapes is also used in forestry as a template to manage the forest for wood production. This approach, keeping biodiversity and ecological processes associated with natural fire regimes, may also help in maintaining forest productivity and resilience in the face of climate change. This Special Issue aims to synthesize current understanding of factors affecting fire regime characteristics, to present recent research on fire regimes and their effects on forest ecosystems, and to illustrate how this knowledge could be translated into forest or fire management strategies in the context of global change.
    Keywords: QH301-705.5 ; Fire regime ; Natural disturbances ; Wildfire ; Global change ; Forest management ; Forest ecosystems ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: This Urological Cancer 2020 collection contains a set of multidisciplinary contributions to the extraordinary heterogeneity of tumor mechanisms, diagnostic approaches, and therapies of the renal, urinary tract, and prostate cancers, with the intention of offering to interested readers a representative snapshot of the status of urological research.
    Keywords: renal cell carcinoma ; iron ; macrophages ; chelation therapy ; urothelial carcinoma ; transcriptome ; microtubule ; MAP1B ; prognosis ; KLF5 ; androgen receptor ; cell proliferation ; tumorigenesis ; prostate cancer ; precision medicine ; whole genome sequencing ; optical mapping ; therapy ; prostate carcinoma ; prostate mpMRI ; machine learning ; artificial intelligence ; deep learning ; neural network ; angiogenesis ; angiogenic growth factors ; antiangiogenic therapy ; renal tumors ; prevention ; α1-adrenoceptor antagonists ; anoikis ; vascularity ; research model ; oncogenes ; tumor suppressor genes ; MR-guided ; radiotherapy ; MRgRT ; stereotactic ablative radiotherapy ; stereotactic ablative radiation therapy (SABR) ; renal cell cancer ; RCC ; online adaptive ; [68Ga]Ga-PSMA PET/CT ; dual-time point imaging ; delayed imaging ; biphasic imaging ; lesion positivity rate ; CXCL9 ; PD1 ; PD-L1 ; stage T1 NMIBC ; prostatic neoplasms/mortality ; prostatic neoplasms/epidemiology ; SEER Program ; bladder cancer ; transurethral resection ; en-bloc resection ; CPT1A ; fatty acids ; serine ; androgen response ; ROS ; oxidative stress ; DONSON ; Downstream Neighbor of SON ; biomarker ; metastatic spread ; diagnosis ; differential diagnosis ; histopathology ; immunohistochemistry ; stroma signature ; patient-derived xenografts ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: The recognition of the exceptional chemical and biological properties of vanadium compounds has led, in recent decades, to extensive research exploring their chemistry, biochemistry, and medicinal chemistry. Due to the prospective application of vanadium compounds as therapeutic agents against diseases such as diabetes, cancer and those provoked by parasites and bacteria, vanadium coordination chemistry and biochemistry has been an area of extensive research. Currently, the most promising potential uses of vanadium compounds are as nutritional supplements and as anticancer agents potentiated by immunotherapy. Nevertheless, researchers from all over the world are dedicating their efforts to vanadium research related to other potential therapeutic applications of vanadium compounds and to obtain insights into their beneficial effects on health and their modes of action. This Special Issue collected research contributions focused on recent advances in vanadium chemistry, biochemistry, and medicinal chemistry. I expect that this collection will have a great impact on the future direction of vanadium research.
    Keywords: polyoxometalates ; decavanadate ; cytotoxicity ; insulin-like activity ; diabetes therapy ; vanadium biochemistry ; vanadium speciation ; vanadium ; proteins ; DNA ; fluorescence ; binding constants ; mechanism of action ; oxidovanadium(V) ; vanadium Schiff base coordination complex ; low acute toxicity ; Oxidovanadium(V) ; Schiff base ; X-ray crystallography ; DNA interaction ; 2-aminopyrimidinium ; experimental and theoretical characterization ; DFT ; docking RNA/DNA ; vitamin E ; EPR ; tocopherol ; 51V NMR ; urethane ; aerosol delivery ; lung cancer ; apoptosis ; antineoplastic ; oxidovanadium(IV) phenantrholine chrysin ; vanadium cellular uptake ; anticancer ; albumin interaction ; glycosylated flavonoid ; oxidovanadium(IV) complex ; antitumoral ; antioxidant ; cell signaling ; cancer ; anticancer agents ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: This book includes the 14 articles accepted and published in the Special Issue “Partial Least Squares Structural Equation Modeling (PLS-SEM): Applications in Economics and Finance” of the MDPI journal Mathematics, which encompasses a wide range of topics connected with the theory and applications of PLS-SEM methodology. These topics involve, among others, prediction of stock market investment intention, institutional quality and international competitiveness, governance paradigms and public innovation, information and communication technologies in the supply chain, influence of the ability to absorb information from the environment and proactivity on the company's results, quality management, effects of the corporate social responsibility on financial performance, resource management for the improvement of the healthcare system, and the application of maximum entropy bootstrapping to time series. It is expected that the book will prove worthwhile and helpful for those working in the area of PLS-SEM, regardless of the field of application (economics, finance, marketing, education or other). Applications of higher order constructs, mediating variables, multigroup analysis and the latest advances in applied methodology can all be found in this book.
    Keywords: self-consciousness ; e-commerce ; consumer behavior ; Technology Acceptance Model ; risk tolerance ; financial well-being ; financial literacy ; overconfidence bias ; herding behavior ; social interaction ; investment intention ; stock market participation ; institutional quality ; international competitiveness ; emerging economies ; PLS-SEM ; lean manufacturing ; quality management ; commercial performance ; wastes ; DIRFT ; luxury fashion goods ; status consumption ; status quo ; clothing innovativeness ; clothing involvement ; PLS-PM ; public service logic ; new public management ; innovation ; co-creation ; co-production ; Spain ; cognitive destination image ; cruise ; satisfaction ; loyalty ; behavioral intention ; structural equation modeling ; National Health Services ; health–disease status ; health system performance ; health system sustainability ; health policy ; healthcare quality ; partial least squares structural equation modeling (PLS-SEM) ; structural equation model ; information and communication technology ; ICT integration ; PLS-SEM bootstrapping ; PLS-SEM with time series ; marketing mix modeling ; maximum entropy bootstrapping ; proactivity ; absorptive capacity ; potential absorptive capacity ; realised absorptive capacity ; structural equation modelling ; video tutorials ; blended learning ; online learning ; financial mathematics ; COVID-19 ; autonomy ; effectiveness ; CO2 emissions ; ESDA ; China ; corporate social responsibility ; corporate performance ; human resources management ; customer satisfaction ; partial least squares structural equation modelling (PLS-SEM) ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint includes 16 original articles published in a Special Issue that focuses on the pathological significance of amyloid-β in neurodegenerative diseases, such as Alzheimer’s disease, the main cause of dementia. Collections in this reprint provide novel insights into the underlying mechanisms and therapeutic potentials of repositioning drugs and new agents for Alzheimer’s disease and related dementias. These findings are expected to contribute to the development of innovative strategies for the prevention and treatment of such diseases.
    Keywords: activation phenotypes ; microglia ; neuroinflammation ; immunohistochemistry ; temporal cortex ; Alzheimer’s disease ; amyloid ; amyloid β-protein (Aβ) ; mAb158 ; oligomers ; protofibrils ; amyloid aggregation ; supported lipid bilayers ; time-lapse AFM ; molecular dynamics simulation ; alzheimer’s disease ; amyloid β ; bryostatin-1 ; ECE1 ; iPS ; nELAV ; neurotoxicity ; oligomer ; protein kinase C ; α-secretase ; APP mutation ; recessive inheritance ; familial Alzheimer’s disease ; Aβ oligomers ; amyloid imaging ; microbiota ; bacterial amyloid ; FUBA ; curli ; CsgA ; amyloid beta ; oxidative stress ; supplement ; phosphodiesterase III inhibitor ; cerebral micro-hemorrhage(s) ; cerebral amyloid angiopathy ; amyloid-β protein ; transgenic mice ; NMR ; CD ; Aβ ; β-amyloid peptide ; α/β-discordant ; Dutch-type mutation ; E22Q ; FAD ; Amyloid β ; Polyphenol ; Pro-oxidant ; Alzheimer’s Disease ; molecular imaging ; amyloid β-peptides ; islet amyloid polypeptide ; high-speed atomic force microscopy ; amyloid PET ; tau PET ; amyloid precursor protein ; mutation ; cerebellum ; PBB3 ; PiB ; axon ; traditional medicines ; Polygalae Radix ; diosgenin ; naringenin ; kihito ; amyloid-β ; antimicrobial ; antiviral ; antimicrobial peptide ; neurodegenerative disease ; misfolding ; fluorescence microscopy ; FRET ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-11-30
    Description: Copper-based catalysts possess important applications in diverse reactions and have received considerable attention from material and catalysis researchers. A great challenge in this field is the facile synthesis of copper-based catalysts with enhanced catalytic activity, selectivity, and durability. This Special Issue of Catalysts, entitled “Synthesis and Applications of Copper-based Catalysts”, presents state-of-the-art synthetic strategies for copper-based catalysts, as well as information on their structure and catalytic use in heterogeneous and homogeneous catalysis, which is helpful for developing novel high-efficiency Cu-based catalysts and synthetic methodology, and for exploring their new catalytic applications.
    Keywords: metal-organic frameworks ; Cu2O ; styrene oxidation ; H2O2 ; base free ; low-temperature ; CO-SCR ; Cu-Mn oxide spinels ; Cu/Cu3P nanoarrays ; Cu nano-substrates ; electrocatalyst ; HER ; ceria ; hydride ; CO2 hydrogenation ; single Cu doping ; density functional theory ; Cu-based catalysts ; CO + NO ; catalytic performances ; O2 resistance ; H2O and SO2 resistance ; adsorption ; dissociation ; density-functional theory calculations ; Cu-skin Cu3Au(111) surface ; CO catalytic oxidation ; CO preferential oxidation ; template ; CTAB ; mixed oxides ; copper oxides ; tin oxides ; BCN/graphene composite ; CVD ; anti-corrosion ; organocopper reagents ; Cu catalysts ; 1,4-conjugate addition ; sulfur heterocycles ; thiochromone ; thioflavanones ; 2-alkylthiochroman-4-ones ; copper ; catalysis ; amination ; amines ; polyamines ; aryl halides ; adamantane ; nanoparticles ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-08-12
    Description: The extraction and exploration of cellulose-based polymers is an exciting area of research. For many years, wood (especially from bleached kraft wood pulp) was considered the main source of cellulosic compounds because of its abundance in nature. However, in the past decade, researchers have been devoted to finding alternatives to extract cellulose from byproducts of agricultural crops and/or textile wastes, which are both highly available at a very reduced raw material cost. This book brings together original research that details the recent progresses and new developments in this field, and how this research is contributing to a circular economy.
    Keywords: citrus sinensis ; nano-fibrillated cellulose ; silver nanoparticles ; acid hydrolysis ; heavy metal sorption ; anaerobic digestion ; biofuel ; biomass ; cotton-based waste ; closed-loop ; lignocellulose ; textile waste ; cellulose nanofibre ; green materials ; biopolymers ; environmental ; recycled newspaper ; composite laminates ; water resistance ; high strength ; cotton wastes ; textile ; nanomaterials ; cellulose nanocrystal ; extraction methods ; environmental application ; regenerated cellulose fiber ; Au NP ; controllably assembled ; SERS ; dimetridazole ; cellulose hydrogel ; thermo-responsive ; sustained release ; silver sulfadiazine ; burn wound ; polymer ; carpet fiber ; direct analysis in real time ; time of flight ; mass spectrometry ; function switching ; oleamide ; cellulose nanofibers isolation ; carpet wastes ; supercritical carbon dioxide ; enhanced properties ; recovery of cellulose ; textile fibers ; eco-efficiency ; circular economy ; textile industry ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Concerns have been raised with respect to the state of high-altitude and high-latitude treelines, as they are anticipated to undergo considerable modifications due to global changes, and especially due to climate warming. As high-elevation treelines are temperature-limited vegetation boundaries, they are considered to be sensitive to climate warming. As a consequence, in this future, warmer environment, an upward migration of treelines is expected because low air and root-zone temperatures constrain their regeneration and growth. Despite the ubiquity of climate warming, treeline advancement is not a worldwide phenomenon: some treelines have been advancing rapidly, others have responded sluggishly or have remained stable. This variation in responses is attributed to the potential interaction of a continuum of site-related factors that may lead to the occurrence of locally conditioned temperature patterns. Competition amongst species and below-ground resources have been suggested as additional factors explaining the variability in the movement of treelines. This Special Issue (book) is dedicated to the discussion of treeline responses to changing environmental conditions in different areas around the globe.
    Keywords: QH301-705.5 ; QK1-989 ; Q1-390 ; n/a ; tree seedling recruitment ; shrubline ; light quality ; higher altitude ; precipitation ; experimental rain exclusion ; Pinus cembra ; Changbai Mountain ; treeline dynamics ; fungal ecology ; thermal continentality ; tree regeneration ; elevational transect ; monitoring ; conifer shrub ; plant water availability ; permafrost ; foehn winds ; treeline ; Holocene ; nitrogen cycling ; carotenoids ; timberline ; 15N natural abundance ; spectrometer ; basal area increment ; palynology ; xylem embolism ; diversity ; elevational treeline ; European Alps ; temperature ; tree line ; winter stress ; photosynthetic pigments ; Pinus sibirica ; westerly winds ; relative air humidity ; ecosystem manipulation ; Larix decidua ; microsite ; polar treeline ; Central Austrian Alps ; Switzerland ; multi-stemmed growth form ; conifers ; forest edge ; history of treeline research ; soil drought ; dendroclimatology ; knowledge engineering ; Rocky Mountains ; apical control ; cloud ; postglacial ; alpine timberline ; space-for-time substitution ; climate change ; expert elicitation ; shoot elongation ; pit aspiration ; climate warming ; climate zone ; alpine treeline ; refilling ; Abies sibirica ; growth trend ; western Montana ; light quantity ; Picea abies ; Mediterranean climate ; forest climatology ; altitude ; environmental stress ; sub-Antarctic ; Erman’s birch ; photoinhibition ; tocopherol ; elevational gradients ; NDVI ; long-term trends ; sap flow ; peat ; tree seedlings ; Southern Ocean ; chlorophyll ; non-structural carbohydrates (NSCs) ; drought ; upward advance ; remote sensing data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This Special Issue, “Plant Oxidative Stress: Biology, Physiology, and Mitigation”, published 11 original research works and 1 review article that discussed the various aspects of ROS Biology, metabolism, and the physiological mechanisms and approaches to mitigating oxidative stress. These types of research studies show further directions for the development of crop plants that are tolerant to abiotic stress in the era of climate change.
    Keywords: heat stress ; grafting ; cucumber ; bitter-melon rootstock ; polyamines ; photosynthesis ; salicylic acid ; chlorophyll fluorescence ; excess boron ; lipid peroxidation ; enzymatic antioxidant ; glutathione ; proline ; stomatal conductance ; arsenic stress ; soybean ; growth ; antioxidant enzymes ; ascorbate–glutathione cycle ; glyoxalase system ; altitudinal variation ; antioxidant activity ; bioactive compounds ; endemic species ; oxidative damage ; sequential application of antioxidants ; salinity ; Cucumis sativus ; photosynthetic efficiency ; antioxidant defense systems ; antioxidants ; cadmium ; oxidative stress ; peptone ; spinach ; alpha-tocopherol ; foliar spray ; okra varieties ; salt ; drought ; plants ; ROS ; genomics ; approaches ; integration ; abiotic stress ; antioxidant defense ; phytohormones ; pulse crop ; water deficit ; AsA-GSH pathway ; methylglyoxal ; micronutrient ; osmoregulation ; reactive oxygen species ; trace elements ; Olea europaea L. ; selenium biofortification ; olive pollen ; cytosolic Ca2+ ; Cucurbita pepo (L.) ; mineral uptake ; nucleic acids ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PST Botany & plant sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Forests cover 30% of the Earth’s land area, or nearly four billion hectares. Enhancing the benefits and ecosystem services of forests has been increasingly recognized as an essential part of nature-based solutions for solving many emerging global environmental problems today. A core science supporting forest management is understanding the interactions of forests, water, and people. These interactions have become increasingly complex under climate change and its associated impacts, such as the increases in the intensity and frequency of drought and floods, increasing population and deforestation, and a rise in global demands for multiple ecosystem services including clean water supply and carbon sequestration. Forest watershed managers have recognized that water management is an essential component of forest management. Global environmental change is posing more challenges for managing forests and water toward sustainable development. New science on forest and water is critically needed across the globe. The International Forests and Water Conference 2018, Valdivia, Chile (http://forestsandwater2018.cl/), a joint effort of the 5th IUFRO International Conference on Forests and Water in a Changing Environment and the Second Latin American Conference on Forests and Water provided a unique forum to examine forest and water issues in Latin America under a global context. This book represents a collection of some of the peer-reviewed papers presented at the conference that were published in a Special Issue of Forests.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; social capital ; Cambodia ; forest and water policy ; land use and land cover change ; shrubland ; “Forests to Faucets” ; precipitation gradient ; forest ecosystem management ; afforestation ; connectivity ; land use change ; forest operations ; Chile ; catchment management ; forest plantation ; climate change ; compound wildfire-water risk ; native forest ; hydrology ; wetland ; streamside native buffer ; sustainability ; participatory monitoring ; hydrological modeling ; timber harvesting ; water quality ; native forests ; source water protection ; global change ; forest hydrology ; community drinking-water ; SDGs ; drinking-water security ; Oregon ; forest ; aquatic-riparian ecosystems ; NDC ; heat: moisture index ; watershed management ; load ; Rhyacotriton ; ecohydrology ; nutrient concentrations ; multi-criteria analysis ; Loess Plateau ; dissolved organic matter ; US Pacific Northwest ; soil moisture ; agricultural lands ; water management ; water provision ; water supply ; forests ; post-fire hydrology ; grassland ; forest plantations ; restoration strategy ; riparian buffer zones ; Mekong ; riparian vegetation ; density management harvest ; SWAT model ; forest watersheds ; water governance ; Nenjiang River ; forestry ; ecosystem services ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-08-12
    Description: This reprint describes recent advances made in the field of antifungal development, especially the discovery of new drugs and drug repurposing. The articles presented in this book provide useful information and insight for the development of new antifungal drugs or intervention strategies. The identification of new, safe molecules, and cellular targets, as well as the elucidation of their antifungal mechanisms of action, will further the effective control of fungal pathogens, especially those resistant to current therapeutic agents.
    Keywords: nanoparticles ; fungi ; drug delivery systems ; marine ; biological synthesis ; myconanotechnology ; canesten ; clotrimazole ; vulvovaginal ; vaginitis ; mycosis ; candidosis ; yeast infection ; candida ; candida albicans ; vaginal health ; anticandidal activity ; indazole ; pyrazole ; 3-phenyl-1H-indazole ; drug design ; acetylsalicylic acid (ASA, aspirin) ; capsule ; CAP64 ; Cryptococcus ; membrane potential (ΔΨM) ; photodynamic treatment ; photosensitiser ; ultrastructure ; drug repurposing ; antifungals ; repositioning ; yeasts ; emerging fungi ; multidrug resistance ; therapeutic alternatives ; new targets ; Candida auris ; Aspergillus spp. ; antifungal ; beta-glucan ; polycations ; Galleria mellonella model ; retinoids ; Candida spp. ; onychomycosis ; Malassezia spp. ; dermatophytes ; microbiology ; mycology ; all-trans retinoic acid ; Acanthamoeba ; free-living ameba ; Acanthamoeba keratitis ; isavuconazonium sulfate ; cyst ; drug ; drug discovery ; drug targets ; invasive aspergillosis treatment ; invasive fungal infections ; fission yeast ; cell wall ; β(1,3)-D-glucan synthase ; antifungal drugs ; echinocandin drugs ; echinocandin resistance ; Fks resistance hot spots ; cytokinesis ; septation ; cell separation ; cell integrity ; cell lysis ; sporotrichosis ; Felis catus ; quinones ; hydrazones ; zoonoses ; host-directed drug therapy ; azoles ; polyenes ; echinocandins ; viral infections ; azole ; synergy ; resistance ; Candida ; natural products ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: This reprint focuses on recent aspects of gravitational theory and cosmology. It contains subjects of particular interest for modified gravity theories and applications to cosmology, special attention is given to Einstein–Gauss–Bonnet, f(R)-gravity, anisotropic inflation, extra dimension theories of gravity, black holes, dark energy, Palatini gravity, anisotropic spacetime, Einstein–Finsler gravity, off-diagonal cosmological solutions, Hawking-temperature and scalar-tensor-vector theories.
    Keywords: Gauss–Bonnet ; innermost stable circular orbits ; spinning test particle ; Einstein-Maxwell-scalar black holes ; modified gravity theory ; Hawking-Page phase transition ; regular black hole ; Minkowski core ; Lambert W function ; black hole mimic ; modified and massive gravity ; two measure theories ; Einstein and Finsler gravity ; off-diagonal cosmological solutions ; nonholonomic dynamical Weyl-scale symmetry breaking ; (anisotropic) inflation ; dark energy ; reconstructing procedure ; Einstein–Gauss–Bonnet gravity ; nonlinear electrodynamics ; hawking temperature ; entropy ; heat capacity ; black hole shadow ; energy emission rate ; quasinormal modes ; cosmology ; torsion ; multifield cosmology ; anisotropic spacetimes ; Kantowski–Sachs ; anisotropic inflation ; galactic rotation ; nonspherical gravitational sources ; modified gravity ; cosmology:theory ; large-scale structure of universe ; gravitation ; fractional-dimension gravity ; dark matter ; cosmological dynamics ; Weyl integrable theory ; scalar field ; interaction ; Painlevé–Gullstrand metrics ; Lense–Thirring metric ; Killing tensor ; Killing–Yano tensor ; separability ; Carter constant ; geodesic integrability ; isometric embeddings ; symmetrical surfaces ; free embedding ; unfolded embedding ; Regge–Teitelboim gravity ; embedding theory ; black hole ; magnetic field ; chaos ; symplectic integrator ; non-linear symmetry realization ; conformal symmetry ; Ricci-based gravity ; Palatini gravity ; exoplanets ; planet’s interior ; electromagnetic ; covariant ; field ; constraints ; curved space ; alternative theories of gravity ; supermassive black hole ; stellar dynamics ; variation of constants ; inflation ; f(R)-gravity ; k-inflation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    Publication Date: 2023-12-20
    Description: Emergent quantum mechanics explores the possibility of an ontology for quantum mechanics. The resurgence of interest in ""deeper-level"" theories for quantum phenomena challenges the standard, textbook interpretation. The book presents expert views that critically evaluate the significance—for 21st century physics—of ontological quantum mechanics, an approach that David Bohm helped pioneer. The possibility of a deterministic quantum theory was first introduced with the original de Broglie-Bohm theory, which has also been developed as Bohmian mechanics. The wide range of perspectives that were contributed to this book on the occasion of David Bohm’s centennial celebration provide ample evidence for the physical consistency of ontological quantum mechanics. The book addresses deeper-level questions such as the following: Is reality intrinsically random or fundamentally interconnected? Is the universe local or nonlocal? Might a radically new conception of reality include a form of quantum causality or quantum ontology? What is the role of the experimenter agent? As the book demonstrates, the advancement of ‘quantum ontology’—as a scientific concept—marks a clear break with classical reality. The search for quantum reality entails unconventional causal structures and non-classical ontology, which can be fully consistent with the known record of quantum observations in the laboratory.
    Keywords: Q1-390 ; QC1-999 ; non-locality ; ultraviolet divergence ; constraints ; Kilmister equation ; bohmian mechanics ; epistemic agent ; Bohmian mechanics ; relational space ; Feynman paths ; Langevin equation ; quantum causality ; emergent quantum gravity ; quantum ontology ; interpretations ; emergent quantum state ; undecidable dynamics ; molecule interference ; emergent quantum mechanics ; no-hidden-variables theorems ; mind–body problem ; physical ontology ; quantum foundations ; matter-wave optics ; conscious agent ; diffusion constant ; Bell theorem ; Burgers equation ; objective non-signaling constraint ; self-referential dynamics ; Bell inequality ; interpretation ; photochemistry ; Born rule statistics ; sub-quantum dynamics ; dynamical chaos ; weak measurement ; p-adic metric ; Levi-Civita connection ; David Bohm ; H-theorem ; the causal arrow of time ; strong coupling ; vortical dynamics ; fundamental irreversibility ; magnetic deflectometry ; quantum thermodynamics ; de Broglie–Bohm interpretation of quantum mechanics ; wavefunction nodes ; stochastic quantum dynamics ; entropic gravity ; metrology ; Schrödinger equation ; gauge freedom ; Monte Carlo simulations ; micro-constituents ; nonequilibrium thermodynamics ; Bell’s theorem ; emergent space-time ; spin ; quantum field theory ; time-symmetry ; Gaussian-like solutions ; Hamiltonian ; number theory ; fractional velocity ; ergodicity ; fractal geometry ; atomic metastable states ; operator thermodynamic functions ; Canonical Presentation ; Retrocausation ; interpretations of quantum mechanics ; Bohm theory ; quantum mechanics ; zero-point field ; conspiracy ; pilot wave ; quantum holism ; toy-models ; curvature tensor ; Aharonov–Bohm effect ; computational irreducibility ; Stochastic Electrodynamics ; diffraction ; retrocausality ; resonances in quantum systems ; stochastic differential equations ; Bianchi identity ; past of the photon ; commutator ; relational interpretation of quantum mechanics ; free will ; nomology ; trajectories ; primitive ontology ; Mach–Zehnder interferometer ; weak values ; singular limit ; interior-boundary condition ; Poincaré recurrence ; quantum inaccessibility ; symplectic camel ; surrealistic trajectories ; observables ; Stern-Gerlach ; decoherence ; quantum non-equilibrium ; generalized Lagrangian paths ; superdeterminism ; black hole thermodynamics ; nonlocality ; measurement problem ; entropy and time evolution ; bouncing oil droplets ; spontaneous state reduction ; quantum theory ; many interacting worlds ; complex entropy. ; Turing incomputability ; iterant ; space-time fluctuations ; quantum potential ; ontological quantum mechanics ; photon trajectory ; Dove prism ; the Friedrichs model ; contextuality ; discrete calculus ; transition probability amplitude ; gravity ; pilot-wave theory ; matter-waves ; de Broglie-Bohm theory ; covariant quantum gravity ; atom-surface scattering ; de Broglie–Bohm theory ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: This Special Issue of Entropy, titled “Recent Advances in Single-Particle Tracking: Experiment and Analysis”, contains a collection of 13 papers concerning different aspects of single-particle tracking, a popular experimental technique that has deeply penetrated molecular biology and statistical and chemical physics. Presenting original research, yet written in an accessible style, this collection will be useful for both newcomers to the field and more experienced researchers looking for some reference. Several papers are written by authorities in the field, and the topics cover aspects of experimental setups, analytical methods of tracking data analysis, a machine learning approach to data and, finally, some more general issues related to diffusion.
    Keywords: diauxic growth ; replicator equation ; mesoscopic model ; integro-differential equations ; anomalous diffusion ; statistical analysis ; single-particle tracking ; trajectory classification ; fractional Brownian motion ; estimation ; autocovariance function ; neural network ; Monte Carlo simulations ; multifractional Brownian motion ; power of the statistical test ; machine learning classification ; feature engineering ; confinement ; information theory ; Brownian particle ; stochastic thermodynamics ; CTRW ; diffusing-diffusivity ; occupation time statistics ; wound healing dynamics ; single pseudo-particle tracking ; phase contrast image segmentation ; 3D single-particle tracking ; Fisher information ; non-uniform illumination ; SPT ; deep learning ; residual neural networks ; random walk ; heterogeneous ; endosomes ; single particle trajectory ; stochastic processes ; trapping ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: The worldwide emergence of antimicrobial-resistant bacteria, specially those resistant to last-resource antibiotics, is now a common problem being defined as one of three priorities for the safeguarding of One Health by the Tripartite Alliance, which includes the World Health Organization (WHO), the Food and Agriculture Organization (FAO) and the Office International des Epizooties (OIE). Bacteria resistance profiles, together with the expression of specific virulence markers, have a major influence on the outcomes of infectious diseases. These bacterial traits are interconnected, since not only the presence of antibiotics may influence bacterial virulence gene expression and consequently infection pathogenesis, but some virulence factors may also contribute to an increased bacterial resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential for decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine. However, the role of natural environments as important components of the dissemination cycle of these strains has not been consider until recently. This Special Issue aims to publish manuscripts that contribute to the understanding of the impact of bacterial antimicrobial resistance and virulence in the three areas of the One Health triad–i.e., animal, human and environmental health.
    Keywords: MRSA ; EMRSA-15 ; MLSB ; bacteremia ; bloodstream infections ; antibiotic resistance ; aquatic contamination ; probabilistic sampling ; San Francisco Estuary ; coast ; Pseudomonas ; Shewanella algae ; Vibrio parahaemolyticus ; biocide ; Listeria monocytogenes ; biofilm ; planktonic culture ; pulsed-field gel electrophoresis ; Escherichia coli ; fosfomycin ; nitrofurantoin ; antimicrobial resistance ; antibiotic susceptibility ; WGS ; phylogenetic analysis ; DNA mismatch repair system ; Salmonella Choleraesuis ; Iberian pig ; wild boar ; phylogenetic relationship ; plasmid replicon typing ; colistin ; carcass ; cfr gene ; fexA gene ; linezolid ; mutation ; pig ; public health ; S. aureus ; avian colibacillosis ; salmonellosis ; MDR ; tetA ; nisin ; mutant prevention concentration ; mutant selection window ; antimicrobial susceptibility testing ; horizontal gene transfer ; Salmonella ; reptiles ; isolation ; biofilms ; chlorhexidine gluconate ; wounds ; Gram-negative bacteria ; colonization ; infection ; clonal lineages ; resistance genes ; virulence factors ; Staphylococcus aureus ; skin and soft-tissue infections ; plasmids ; Panton–Valentine leucocidin ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: The book continues with an experimental analysis conducted to obtain accurate and complete information about electric vehicles in different traffic situations and road conditions. For the experimental analysis in this study, three different electric vehicles from the Edinburgh College leasing program were equipped and tracked to obtain over 50 GPS and energy consumption data for short distance journeys in the Edinburgh area and long-range tests between Edinburgh and Bristol. In the following section, an adaptive and robust square root cubature Kalman filter based on variational Bayesian approximation and Huber’s M-estimation is proposed to accurately estimate state of charge (SOC), which is vital for safe operation and efficient management of lithium-ion batteries. A coupled-inductor DC-DC converter with a high voltage gain is proposed in the following section to match the voltage of a fuel cell stack to a DC link bus. Finally, the book presents a review of the different approaches that have been proposed by various authors to mitigate the impact of electric buses and electric taxis on the future smart grid.
    Keywords: Q1-390 ; QC1-999 ; adaptive ; electric vehicle ; state of charge (SOC) ; high voltage gain ; lithium-ion battery ; climate change ; ssustainable transport ; driving cycle ; smart grid ; robust ; battery powered vehicle ; Huber’s M-estimation ; electric taxi ; public transportation ; sustainable development ; DC-DC converter ; square root cubature Kalman filter (SRCKF) ; coupled inductor ; fuel cell vehicles ; charging approaches ; ripple minimization current ; variational Bayesian approximation ; electric propulsion ; electric bus ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-07-06
    Description: The 1st International Electronic Conference on Chemical Sensors and Analytical Chemistry was held on 1–15 July 2021. The scope of this online conference was to gather experts that are well-known worldwide who are currently working in chemical sensor technologies and to provide an online forum for the presention and discussion of new results. Throughout this event, topics of interest included, but were not limited to, the following: electrochemical devices and sensors; optical chemical sensors; mass-sensitive sensors; materials for chemical sensing; nano- and micro-technologies for sensing; chemical assays and validation; chemical sensor applications; analytical methods; gas sensors and apparatuses; electronic noses; electronic tongues; microfluidic devices; lab-on-a-chip; single-molecule sensing; nanosensors; and medico-diagnostic testing.
    Keywords: electrochemical sensors ; carbon nanotubes ; electropolymerization ; gallic acid ; ellagic acid ; syringaldehyde ; vanillin ; cognac and brandy carbon dots ; pH sensing ; active surface preservation ; nanosensor ; fluorescence ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.
    Keywords: QH301-705.5 ; Q1-390 ; thermodynamic modeling ; molecular dynamics simulation ; poorly soluble drugs ; amorphous solid dispersions ; dissolution enhancement ; crystallization tendency ; continuous processing ; stability ; milling ; granulation ; thermal analysis ; amorphous ; ball milling ; pharmaceutical glass ; dissolution ; rebamipide ; poloxamer ; classification ; polyelectrolytes ; amorphisation ; self-assembly ; dissolution rate ; miscibility ; bioavailability ; solubility ; evaporation ; mesoporous ; polyelectrolyte excipient matrix ; polymer ; bicaludamide ; phase diagram ; Weibull dissolution model ; spectroscopic techniques ; anticancer drugs ; manufacturing methods ; nucleation ; molecular complex ; nanoaggregates ; enrofloxacin ; accelerated stability test ; solubility enhancement ; amorphous solid dispersion ; tadalafil ; process development ; amorphous polymeric salt ; Wood’s apparatus ; hot melt extrusion ; solid dispersions ; intrinsic dissolution rate ; solid dispersion ; interaction ; crystallization ; spray drying ; characterization ; ciprofloxacin ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The plant kingdom, with its terrestrial and marine natural products, has been widely explored. Plant-based products have long been used to prevent and treat various ailments. Many natural compounds have been reported to have a variety of interesting and significant biological activities, including antioxidant, anti-inflammatory, antitumor, antibacterial, antiviral, antifungal, antiparasitic, analgesic, antidiabetic, anti-atherogenic, and antiproliferative, as well as cardioprotective and neuroprotective properties. Therefore, researchers pay special attention to the bioactive compounds synthesized by plants. Opportunities in functional ingredients and treatment of NCDs (oxidative stress, diabetes, obesity, metabolic syndrome, etc.) are widely explored. However, many therapeutic properties of plants are still to be discovered. This Special Issue reprint intends to substantially contribute to our knowledge of their beneficial properties. Natural products could be a vast resource in respect of human well-being improvement. This Special Issue reprint also aims to disseminate some of the most recent and significant contributions in natural product research on phytochemicals and biological activity.
    Keywords: Sempervivum tectorum L. ; mineral content ; bioavailable fraction ; heavy metals ; open-field plants ; tissue culture plants ; in vitro callus culture ; Rubus subg. Rubus Watson ; Vaccinium corymbosum L. ; phenolics ; radical scavenging activities ; ferric reducing power ; waste peel ; essential oil ; GC-MS ; volatile compounds ; antimicrobial activity ; chemical composition ; antioxidant activity ; fluorescence ; total phenolic content ; Aspergillus flavus ; maize ; peel extracts ; AFB1 ; qRT-PCR ; Opuntia spp. ; phytochemicals ; biological activities ; antioxidant capacity ; chemopreventive effect ; integrated pest management ; Oriental fruit fly ; pomology ; post-harvest disease control ; Sambucus nigra L. ; medicinal plants ; flavonoids ; phenols ; carbohydrates ; amino acids ; Flos Abelmoschus manihot ; medicinal part ; non-medicinal parts ; UFLC-Triple TOF-MS/MS ; metabolite profiling ; multivariate statistical analysis ; juniper ; natural products ; tree ; leaves ; disease ; bioactive compounds ; microbial resistance ; turmeric ; Curcuma aromatica ; Curcuma caesia ; Curcuma longa ; Curcuma zanthorrhiza ; enantiomeric distribution ; chiral ; cultivars ; foliar sprays ; Humulus lupulus ; liming ; phenolic compounds ; plant vigour ; polyphenols ; antimicrobial activity enhancement ; ascorbic acid ; Maillard reaction products ; laccase–mediator system ; horseradish peroxidase–H2O2 system ; tomato pomace ; by-product utilization ; finger millet ; gluten-free ; potato flour ; convenience food ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint compiles several studies on radiation interactions with biomolecules. The fragmentation induced by slow electron and electron scattering processes are described, and the induced processes by UV radiation are characterised. The present Special Issue offers complementary studies on radiation induced by photons and electrons in biological (and related) target molecules. The present collection provides important insights on radiation physics and chemistry and the advances in knowledge in these areas.
    Keywords: methane ; cross-section ; elastic scattering ; electrons ; CRISPR/Cas9 ; DNA cleavage ; ECD ; spectroscopy ; guide RNA ; RNP complex ; SpCas9 ; radiosensitizer ; low-energy electron ; dissociative electron attachment ; roaming ; tirapazamine ; predissociation ; electron scattering cross sections ; benzene ionization ; VUV photoabsorption ; halopyrimidines ; valence and Rydberg states ; time-dependent density functional theory ; radiosensitizers ; taurine ; elastic constant ; Brillouin scattering ; acoustic mode ; negative ions ; oxaloacetic acid ; citric acid ; mass spectrometry ; anticancer drugs ; cisplatin ; platinum (II) halo-carbonyl complexes ; low-energy electrons ; dissociative ionization ; focused electron beam induced deposition ; sevoflurane ; pheomelanin ; nitrotyrosine ; dityrosine ; photooxidation ; photosensitizer ; IR radiation ; horseradish peroxidase ; catalase ; alkaline phosphatase ; antioxidant ; vapor ; coherent domain ; anion–molecule collisions ; electron detachment cross sections ; positive ion-induced fragmentation ; molecular dynamics ; radiotherapy ; X-ray ; modified nucleosides ; DNA damage ; hypoxia ; chemoradiation ; low-energy electron interaction ; perfluorination ; HF formation ; pentafluorothiophenol ; 2-fluorothiophenol ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-10-25
    Description: This reprint reports on new advances in basic and applied research of soil pollution and remediation. A list of contaminants are targeted, including toxic metal(loid)s (e.g., Pb, As, Sb, and multi-metals), organic contaminants (e.g., organochlorine pesticides, phenanthrene, and petroleum), and antibiotics (e.g., sulfadiazine). The occurrence, environmental behaviors, and risks of these contaminants are explored. Special attention is devoted to techniques for the remediation of polluted soils, such as stabilization/solidification, photocatalytic degradation, and thermal desorption. This reprint provides new insights into soil pollution and remediation.
    Keywords: miyun reservoir ; pollution assessment ; binary mixing model ; source appointment ; illegal use ; non-point source pollution ; agricultural use ; veterinary use ; Three Gorges ; sulfadiazine ; Cu2+ co-existence ; paddy soils ; adsorption ; soil properties ; β-CD modified BC ; stabilization/solidification ; response surface methodology ; synchronous adsorption investigations ; PHe ; primary explosives site ; heavy metal contamination ; antimony ; co-occurring metal ; Fe–Al-based amendment ; immobilization ; heavy metals ; input flux ; source ; management ; garland chrysanthemum ; lettuce ; antioxidant defense enzymes ; GSH ; PCs ; comprehensive evaluation method ; contaminated soil ; ex situ thermal desorption ; environmental impact ; resource utilization ; low-molecular-weight organic acid salts ; phosphate ; arsenic-contaminated soil ; microorganisms ; nano zero-valent iron (nZVI) ; biochar ; photocatalysis ; synergy ; TPH ; soil ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics ; bic Book Industry Communication::T Technology, engineering, agriculture::TQ Environmental science, engineering & technology::TQK Pollution control
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Rivers have been intensively degraded due to increasing anthropogenic impacts from a growing population in a continuously developing world. Accordingly, most rivers suffer from pressures as a result of increasing dam and weir construction, habitat degradation, flow regulation, water pollution/abstraction, and the spread of invasive species. Science-based knowledge regarding solutions to counteract the effects of river degradation, and melding principles of aquatic ecology and engineering hydraulics, is thus urgently needed to guide present and future river restoration actions. This Special Issue gathers a coherent set of studies from different geographic contexts, on fundamental and applied research regarding the integration of ecohydraulics in river restoration, ranging from field studies to laboratory experiments that can be applied to real-world challenges. It contains 13 original papers covering ecohydraulic issues such as river restoration technologies, sustainable hydropower, fish passage designs and operational criteria, and habitat modeling. All papers were reviewed by international experts in ecology, hydraulics, aquatic biology, engineering, geomorphology, and hydrology. The papers herein well represent the wide applicability of ecohydraulics in river restoration and serve as a basis to improve current knowledge and management and to reduce arguments between different interests and opinions.
    Keywords: QH301-705.5 ; Q1-390 ; Fish passage and migration ; Prioritization of river connectivity for sustainable fisheries ; Sustainable hydropower ; Spawning grounds ; Invasive species management ; Environmental flows ; Habitat modeling ; Dam/weir retrofitting and removal ; Riparian and aquatic vegetation dynamics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: Rising pollution, climate change and the depletion of fossil fuels are leading many countries to focus on renewable-based energy conversion systems. In particular, recently introduced energy policies are giving high priority to increasing the use of renewable energy sources, the improvement of energy systems’ security, the minimization of greenhouse gas effect, and social and economic cohesion. Renewable energies’ availability varies during the day and the seasons and so their use must be accurately predicted in conjunction with the management strategies based on load shifting and energy storage. Thus, in order to reduce the criticalities of this uncertainty, the exploitation of more flexible and stable renewable energies, such as the geothermal one, is necessary. Geothermal energy is an abundant renewable source with significant potential in direct use applications, such as in district heating systems, in indirect use ones to produce electricity, and in cogeneration and polygeneration systems for the combined production of power, heating, and cooling energy. This Special Issue includes geothermal energy utilization and the technologies used for its exploitation considering both the direct and indirect use applications.
    Keywords: geothermal power production ; abandoned oil reservoirs ; in situ combustion ; organic Rankine cycle (ORC) ; plunger pump ; centrifugal pump ; pressure drop ; temperature utilization rate ; system generating efficiency ; carbonate geothermal reservoirs ; sustainable geothermal energy exploitation ; southern Italy ; numerical simulation ; dual-loop ORC ; mixture working fluids ; entropy generation ; entransy loss ; exergy loss ; Ground source heat pump ; oval cross-section ; groundwater ; borehole heat exchanger ; CFD ; Sandtank ; granite ; physical characteristics ; cyclic ; thermal treatment ; water cooling ; hybrid renewable polygeneration plant ; micro organic Rankine cycle ; evacuated solar thermal collectors ; photovoltaic panels ; plastic heat exchanger ; Organic Rankine Cycle ; geothermal energy ; shell and tube heat exchanger ; fouling resistance ; mobile thermal energy storage (M-TES) ; phase change material (PCM) ; LCOH ; heat transport ; renewable energy source ; household hybrid system ; dynamic simulation ; economic analysis ; TRNSYS software ; heating and cooling network ; polygeneration system ; geothermal energy community ; ORC ; energy district ; heat pump ; R1234ze ; CO2 ; geothermal ; renewable energy ; historic building ; energy saving ; earth-to-air ; horizontal pipe ; 2D model ; air conditioning ; renewable energy sources ; thermal performances ; energy efficiency ; parametric study ; geothermal resource ; Monte Carlo simulation ; assessment ; thermal reservoir ; North Jiangsu Basin ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint contains 14 articles on various aspects of many-body physics. Most of the articles are devoted to different phenomena in Bose–Einstein condensate (M.R. Pathak and A. Nath; M.H. Figlioli Donato and S.R. Muniz ; B. Halder with coauthors; O.E. Alon).L. Madeira and V.S. Bagnato discuss the route of an out-of-equilibrium system to its thermalized state. M.R. Singh discusses the many-body interactions in plasmonic nanohybrids. M. Pudlak and R. Nazmitdinov analyze electron transport through a one-dimensional quantum ring, subject to Rashba spin–orbit interaction in the presence of external fields. R. Friedberg and J.T. Manassah report computer investigations on the duration memory for storage for an isolated atom. M.C. Pagnacco with coauthors describe the crazy-clock phenomenon. V.I. Yukalov and E.P. Yukalova consider materials with nanoscale phase separation. E.M. Anitas investigates materials with fractal-like geometry. L. Madeira with coauthors address the topic of quantum turbulence. K. Ziegler discusses how the employment of the diagonal elements of the time correlation matrix can be used to probe closed quantum systems that are measured at random times. L. Salasnich analyzes the collective dynamics of electrons in graphene positioned between the two slabs.
    Keywords: plasmonics ; nano-optics ; dipole-dipole interaction ; density matrix method ; dressed states ; Kerr effect ; quantum dots ; metallic nanoparticles ; graphene ; quantum many-body theory ; acoustic plasmons ; Bose-Einstein condensates ; infinite-particle-number limit ; many-body theory ; mean-field theory ; position variance ; momentum variance ; angular-momentum variance ; solvable models ; harmonic-interaction model ; anisotropy ; dynamics of closed quantum systems ; random probing ; separation of time scales ; Hilbert-space localization ; quantum turbulence ; Bose-Einstein condensate ; out-of-equilibrium ; small-angle scattering ; fractional Brownian surfaces ; fractal dimension ; Hurst exponent ; spectral exponent ; nanoscale phase separation ; quasi-equilibrium system ; heterophase mixture ; zeroth-order transition ; nucleation point ; four-color optical lattice ; soliton ; crazy clock ; Briggs–Rauscher reaction ; state I to state II transition ; symmetry breaking ; iodine ; K-means analysis ; random number generator ; non-thermal fixed points ; out-of-equilibrium system ; Bose–Einstein condensate ; turbulence ; Josephson effect ; spinor BEC ; toroidal superfluid ; quantum droplets ; multi-color periodic confinement ; Rashba spin–orbit interaction ; semiconductor quantum ring ; Floquet theory ; light–matter coupling ; magnetic field ; bit retrieval ; long-time memory ; Nyxion ; continuous pump ; coalescence ; Aurora ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 78
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level.
    Keywords: QH301-705.5 ; genome stability ; Trisomies ; microtubule dynamics ; Checkpoints ; Inheritance ; Cell division ; centrosome ; Down Syndrome ; Cell motility ; Cell regulation ; chromosome segregation ; Microtubules ; Cell cycle ; kinetochore ; Cytoskeleton ; Cell reproduction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 79
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: The expansion of urban areas has facilitated the conversion of undeveloped lands, which has led to environmental degradation, such as loss of habitats, hydro-modification, and the collapse of existing ecosystems. Recent climate change has exacerbated these damages by causing more frequent and serious hazards. To attenuate the impacts of urbanization and the negative effects of climate change, green infrastructure (GI) planning (e.g., nature-based strategies, technologies, policies, and solutions) has arisen as an important approach for balancing urban development and nature. GI offers a variety of benefits to our cities by reducing stormwater runoff, heat waves, and air pollution; expanding wildlife habitats; and increasing recreational opportunities and even nearby property values.
    Keywords: stormwater management ; urban heat island ; cost–benefit analysis ; ecosystem services ; urban green infrastructure ; green infrastructure ; indexing ; random forest ; interpretation of machine learning ; urbanization ; shapley additive explanation ; park characteristic ; extreme gradient boost ; Dallas ; land use land cover ; construction site ; particulate matter emissions ; emission factor ; prediction technology ; urban shrinkage ; vacancy parcel data ; multilevel analysis ; predicting vacancy ; access inequity ; systematic mapping ; empirical studies ; city scale ; inequity mitigation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RB Earth sciences::RBP Meteorology & climatology
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  • 80
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-02-01
    Description: Glycosaminoglycans are linear, anionic polysaccharides (GAGs) consisting of repeating disaccharides. GAGs are ubiquitously localized throughout the extracellular matrix (ECM) and to the cell membranes of cells in all tissues. They are either conjugated to protein cores in the form of proteoglycans, e.g., chondroitin/dermatan sulfate (CS/DS), heparin/heparan sulfate (Hep/HS) and keratan sulfate (KS), as well as non-sulfated hyaluronan (HA). By modulating biological signaling GAGs participate in the regulation of homeostasis and also participate in disease progression. The book, entitled “Exploring the multifaceted roles of glycosaminoglycans (GAGs)—new advances and further challenges”, features original research and review articles. These articles cover several GAG-related timely topics in structural biology and imaging; morphogenesis, cancer, and other disease therapy and drug developments; tissue engineering; and metabolic engineering. This book also includes an article illustrating how metabolic engineering can be used to create the novel chondroitin-like polysaccharide.A prerequisite for communicating in any discipline and across disciplines is familiarity with the appropriate terminology. Several nomenclature rules exist in the field of biochemistry. The historical description of GAGs follows IUPAC and IUB nomenclature. New structural depictions such as the structural nomenclature for glycan and their translation into machine-readable formats have opened the route for cross-references with popular bioinformatics resources and further connections with other exciting “omics” fields.
    Keywords: GAGs: ; Hyaluronic ; Acid, ; Heparan ; (Sulfate) ; Heparin, ; Heparosan ; Chondroitin ; Dermatan ; Keratan, ; GAGs ; like ; Peri ; and ; Extracellular ; Matrix ; Regulation ; &amp ; Biosynthesis ; of ; GAG ; Extraction ; Synthesis ; (chemical, ; metabolic ; engineering,...) ; Characterization ; sequence ; molecular ; weight, ; degree ; polymerization, ; 3D ; structures,....) ; structure/properties ; relationships ; oligosaccharides ; Glycobiology ; structure/function ; relationship ; Protein-GAG ; complexes ; in ; disease ; GAG-based ; biomaterials ; as ; nanocarriers ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 81
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: A disease model displays pathological processes observed in human or animal diseases. The models are fundamental tools in biomedical research, and they are invaluable for providing new insights into mechanisms underlying organ function, establishing the pathophysiology of a disease, and testing potential therapeutic approaches.Models have been long used to study several diseases, including cardiovascular, oncologic, metabolic, infectious, and neurological diseases, among others. Animals or cells displaying pathological processes observed in human or animal diseases have been used as models. Moreover, mathematical models are also of great importance to disease modeling. Animal models offer the unique opportunity to investigate the function of genes and pathways and the in vivo effects of drugs, bridging the gap between basic science and the treatment of diseases. The selection of a suitable model system is a crucial step in research design. For disease modeling to be meaningful, a relevant cellular or genetic phenotype must be observed. Without the use of models, both research and clinical practice worldwide would be vastly different today.This Special Issue aimed to publish original research works or reviews with models of disease, highlighting their importance to search for new therapeutic strategies.
    Keywords: spontaneous models ; induced models ; genetically engineered models ; acute kidney injury ; biomarkers ; coagulation ; ischemia-reperfusion injury ; shock ; newborn lamb ; multiple intestinal loop model ; 3R ; Cryptosporidium parvum ; yeast cell wall fractions ; fatty liver disease ; glucose ; imipramine ; insulin ; obesity ; renal impairment ; retinal injury ; xenograft ; ectopic ; orthotopic ; hIBC ; cIMC ; whole-body ischemia ; cardiopulmonary resuscitation ; drug-induced hypothermia ; spinal motor neuron ; inflammation ; paraplegia ; virucidal drugs ; IBV ; chickens ; Coronaviridae ; silver nanoparticles ; artificial ribonuclease ; monoglyceride lauryl acid ; spinal cord hemisection ; Macaca radiata ; predegenerated nerve transplantation ; locomotor recovery ; Cornu Ammonis 1 ; glutaminergic synapse ; memory function ; oligodendrocyte ; pyramidal cells ; animal model ; trichotillomania ; hair-pulling ; body-focused repetitive disorder ; transitional cell carcinoma ; urothelial carcinoma ; histology ; therapeutic marker ; prognosis ; mandibular growth ; mandibular posterior displacement ; mandibular length ; condylar growth ; rat ; class III malocclusion ; orthodontic treatment ; antebrachial growth deformity ; dog ; osteotomy ; patient-specific instrumentation ; 3-D ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 82
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: There is increasingly intensive research for energy storage technologies development due to the enhanced energy needs of the contemporary societies. Increased global energy consumption results in the reduction in the availability of traditional energy resources, such as coal, oil and natural gas. Therefore, there is an urgent need for new systems development based on the conversion and storage of sustainable and clean energy. Phase change materials (PCMs) are one of the key components for the development of advanced sustainable solutions in renewable energy and engineering systems. In order to update the field of renewable energy and engineering systems with the use of PCMs, a Special Issue entitled “Phase Change Materials: Design and Applications” is introduced. This book gathers and reviews the collection of ten contributions (nine articles and one review), with authors from Europe, Asia and Americam accepted for publication in the aforementioned Special Issue of Applied Sciences.
    Keywords: phase change materials ; thermal energy storage ; energy efficiency ; building applications ; construction materials ; phase-change material ; dispersion ; thermal-mechanical stability ; viscosity ; supercooling ; nucleating agent ; cold storage ; battery cooling ; LPMO ; Fourier Transform ac Voltammetry (FTacV) ; cyclic voltammetry ; Direct Electron Transfer (DET) ; lathrate hydrate ; tetrabutylammonium acrylate (TBAAc) ; crystal growth ; ultrasonic vibration ; polyurethane elastomers ; microencapsulated PCMs ; thermal properties ; mechanical properties ; phase change material ; sugar alcohol ; erythritol ; latent heat storage ; thermal stability ; degradation kinetics ; PCM ; mini-channels ; air ; melting ; solidification ; latent heat thermal energy storage ; phase change materials (PCM) ; macro-encapsulation ; rectangular slab ; experimental study ; sodium nitrate ; thermal conductivity ; microencapsulation ; latent heat ; multicriteria decision ; finite element ; automotive ; energy storage ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 83
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This reprint is mainly aimed at economists involved in the energy market. Energy market processes have an enormous impact on people's day-to-day economic activities. The economics of sustainability leads the way in theorizing how best to prevent environmental degradation whilst also fostering positive economic development. For these reasons, the focus of this reprint is mainly on pollution and the energy transition. Works on energy resources and future-oriented solutions that reduce the consumption of classical energy resources are explored in the reprint. Papers relating to contemporary accounting and the stock market are also presented. The geographical area of the works showcased here essentially covers the entire eastern hemisphere of the globe (Asia, Africa and Europe). They are mainly empirical studies, although in one case a bibliometric analysis is included.
    Keywords: energy market ; stock market ; mood ; emotions ; weather ; causality ; industry ; renewable energy ; CO2 emissions ; Sub-Saharan Africa ; pollution charges ; green technology innovation ; industrial enterprise ; heterogeneity analysis ; oil prices ; inflation ; exchange rate ; goodwill ; impairment of goodwill ; quality of financial statements ; energy sector ; mining ; fuel ; disclosures of financial information ; nearly zero-energy housing ; NZEB ; barriers ; perceptions ; housing professionals ; sustainability transition ; energy ; green indicators ; blue indicators ; carbon neutrality ; nonlinear ARDL ; European Union ; sustainable energy development ; energy transformation ; energy strategy ; taxonomical analysis ; ranking ; TOPSIS method ; renewable energy transition ; non-euro area ; panel data ; Granger causality ; VECM ; human capital ; CO2 emission ; FDI ; technological innovation ; carbon emission efficiency ; carbon emission ; renewable energy sources ; government regulations ; subsidy programmes ; prosumers ; micro-installations ; regression discontinuity design ; green taxes ; greenhouse gas emissions ; indicators of reduction in greenhouse gas emissions ; sustainable development ; green energy ; innovation ; trends ; bibliometric analysis ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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  • 84
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Analytical chemistry is bound to face growing challenges in the future, especially for the quantification of trace analytes in complex matrices. Although the development of increasingly sensitive and specific instrumental techniques has achieved remarkable results, sample preparation is still a fundamental step, often limiting the whole workflow. In the context spawned by the recent international environmental policies that are responsive to the rapport of human activities with the surrounding environment, chemistry cannot hesitate to give its contribution. Almost pioneeringly, in analytical chemistry, we have been talking for some time about “green analytical chemistry”, its guiding principles, and the development of eco-friendly analytical approaches. However, the new and still open challenge is advance not only in eco-compatibility but mainly in eco-sustainability, rooting the future of analytical chemistry in new perspective aimed at minimizing the environmental impact of the analytical process by placing environmental cost as a priority aim on par with analytical performance. This is the reprint of a Special Issue that includes contributions focused on the progress in analytical chemistry based on the arguments previously raised and discussed, with a particular reference to eco-compatibility and eco-sustainability. The contributions include the development of low environmental impact methods and/or techniques or their applications.
    Keywords: dyes ; fatty acids ; microextraction ; magnetic ionic liquid ; sample preparation ; dispersive liquid–liquid microextraction ; single drop microextraction ; GC ; HPLC ; ionic liquids ; denitrogenation ; extraction ; pyridine ; quinoline ; aniline ; simulated oil ; adsorption ; gum Arabic ; magnetite ; nano-composite ; lead(II) ; mercury removal ; magnetic ; manganese ; cobalt ; iron ; spinel ; crosslinker ; phenolic acids ; vinylimidazole ; anion exchanger ; co-polymer ; solid-phase extraction ; sustainable analytical sample preparation ; indoor air quality ; fragrances ; indoor pollution ; endocrine disruptors ; analytical method ; GC-MS ; musks fragrances ; emerging contaminants ; α-isomethylionone ; halloysite nanotubes ; organosilyl-sulfonated halloysite nanotubes ; solid phase extraction ; pyrrolizidine alkaloids ; honey ; chlorzoxazone ; greener HPTLC ; paracetamol ; simultaneous detection ; validation ; AGREE ; traditional HPTLC ; vitamin D3 ; pulsed electric field ; bioactive compounds ; optimization ; mushrooms ; Agaricus bisporus ; phenyboronic-acid-functionalized ; Fe3O4 magnetic nanoparticles ; ortho-dihydroxy-containing compounds ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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  • 85
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Accurate solar radiation knowledge and its characterization on the Earth’s surface are of high interest in many aspects of environmental and engineering sciences. Modeling of solar irradiance from satellite imagery has become the most widely used method for retrieving solar irradiance information under total sky conditions, particularly in the solar energy community. Solar radiation modeling, forecasting, and characterization continue to be broad areas of study, research, and development in the scientific community. This Special Issue contains a small sample of the current activities in this field. Both the environmental and climatology community, as the solar energy world, share a great interest in improving modeling tools and capabilities for obtaining more reliable and accurate knowledge of solar irradiance components worldwide. The work presented in this Special Issue also remarks on the significant role that remote sensing technologies play in retrieving and forecasting solar radiation information.
    Keywords: Q1-390 ; QC1-999 ; PAR ; motion vector field ; radiative transfer ; global horizontal irradiance ; evapotranspiration ; HRV ; Kato bands ; understory light condition ; California Delta ; validation ; aerosol impact ; remote sensing ; solar radiation ; nowcasting ; India ; cloud categories ; Clouds and the Earth Radiant Energy System (CERES) ; brightness temperature ; Himawari-8/Advanced Meteorological Imager (Himawari-8/AHI) ; water vapor ; clear sky index ; water resource management ; broadband albedo at the top of the atmosphere (TOA albedo) ; data fusion ; solar energy ; shortwave radiation ; AMESIS ; satellite-derived dataset ; insolation ; solar variability ; subcanopy light regime ; clustering analysis ; solar energy systems ; forest canopy ; radiance ; MSG ; GOES satellites ; radiation model ; solar radiation trends ; clear sky ; downward shortwave radiation ; reflected shortwave radiation at the top of the atmosphere (RSR) ; SEVIRI ; photosynthetically active radiation ; surface solar radiation ; solar irradiance ; earth observation ; high turbidity ; Geostationary Korea Multi-Purse Satellite/Advanced Meteorological Imager (GK-2A/AMI) ; Solis scheme ; solar radiation forecasting ; surface energy balance ; light attenuation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 86
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Dear Colleagues, When Hayflick and Moorhead coined the term “cellular senescence” (CS) almost 60 years ago, this phenomenon was understood as a mechanism, usually induced by activation of the DNA-repair machinery, to prevent uncontrolled proliferation. Meanwhile, additional beneficial roles for CS have been identified, such as embryonic development and wound healing. The senescence associated secretory phenotype (SASP) activated in most senescent cells (SC) signals to the immune system “come here and remove me”. In organisms with young and functional immune systems, occurring SC are usually detected and removed. If SC remain in the tissue expressing the SASP, this will cause not just a damaging local inflammation but can also induce remodeling and regeneration of the surrounding tissue as well as spreading of senescence. Old organisms show reduced regenerative potential and immune function which leads to accumulation of SC. Accordingly, accumulation of SC was observed in tissues of aged individuals, but importantly also in the context of age-related disorders, neurodegenerative, or cardiovascular diseases and others. Because of its detrimental effect of the surrounding tissue, accumulation of SC is not just a consequence, but can rather been understood as a major driver of aging. In line with this, recent studies described that removal of SC showed beneficial effects on healthspan and lifespan. This exciting research led to the discovery of “senolytics”, drugs which can kill SC. Given the heterogeneity of cell types that show senescence-like phenotypes, including heart muscle and post-mitotic neuronal cells, further research is required to unravel the molecular background that renders a cell type vulnerable to senesce. Additionally, it will be important to understand how senescence is cell type-specifically induced and which molecules serve as drug targets to prevent senescence and its spreading, or actively kill SC. This special issue will shed light on the molecular pathways of CS and inflammaging and on possible strategies to interfere with these processes. Dr. Markus Riessland Guest Editor
    Keywords: γH2AX ; Alzheimer’s disease ; DNA damage ; mild cognitive impairment ; senescence ; secreted protein acidic and rich in cysteine ; regeneration ; homeostasis ; cellular senescence ; biology of aging ; neurodegeneration ; brain ; geroscience ; senolytics ; tauopathy ; cancer ; stress response ; post-mitotic ; neuronal senescence ; amyotrophic lateral sclerosis ; senescence-associated secretory phenotype (SASP) ; cell-cycle ; melanoma ; pancreatic adenocarcinoma ; tumor infiltration ; chemotherapy resistance ; prostate ; inflammation ; AIM2 inflammasome ; POP3 ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 87
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This reprint includes impactful chapters related to document-image related visual sensing, which do present and comprehensively discuss selected scientific concepts, frameworks, architectures and ideas on sensing technologies and machine-learning techniques. Indeed, document imaging/scanning approaches are essential techniques for digitalizing documents in various real-world contexts. This reprint emerging from the Special Issue "Document-Image Related Visual Sensors and Machine Learning Techniques” can be viewed as a result of the crucial need for document management systems. Such technologies are being applied in various fields or different domains and parts of the world to address relevant challenges that could not be addressed without the advances made in these technologies. The reprint includes impactful chapters that present scientific concepts, frameworks, architectures and innovative ideas on sensing technologies and machine-learning techniques to overcome a series of key challenges related to document imaging/scanning, text detection, text recognition, and documents clustering.
    Keywords: feature learning ; incomplete multimedia data ; fuzzy c-means ; variational autoencoder ; multispectral imaging ; document scanning ; portable sensor ; depth image filtering ; point clouds filtering ; Kinect v2 ; depth resolution ; close range ; hand pose ; image binarization ; optical character recognition ; document images ; local thresholding ; image pre-processing ; natural images ; scene text recognition ; visual sensor ; text position correction ; encoder-decoder network ; chart recognition ; deep learning ; visualization ; classification ; detection ; perspective correction ; house architecture type classification ; house type classification ; convolutional neural networks ; document classification ; feature selection ; data augmentation ; imbalanced dataset ; scene text detection ; multiple scales ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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  • 88
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-12-06
    Description: This book focuses on the up-to-date studies on the sustainability with changing climate and extremes. The main contributors discussed the changing climate and extreme events, as well as their impacts on natural and human dimension sustainability, including the incorporated social–ecologic and socioeconomic processes. Special attention is given to four main sections: natural disasters in agriculture; urban/rural ecosystem, tourism, and ecosystem service; extreme climate indices, and newly created dataset for climate change.
    Keywords: trade conflict ; carbon emissions ; import and export trade ; cooperative emission reduction ; meteorological hazards ; risk assessment ; spatial pattern ; population exposure ; Qinghai-Tibet Plateau ; climate change ; slope geohazards ; new geohazard clusters ; extreme cooling events ; Arctic Oscillation ; winter in China ; atmospheric circulation ; GPP ; CMIP6 ; ESM ; STA ; China ; warm days ; cold days ; warm nights ; cold nights ; hot days ; frost days ; compound drought and heatwave events ; complex network ; event synchronization ; atmospheric circulation patterns ; urban agglomeration ; drought ; heat wave ; flood ; GM (1, 1) ; Arctic ; universal thermal climate index (UTCI) ; spatial-temporal changes ; 1979–2019 ; ecosystem services trade-offs ; land-use change ; soil conservation ; carbon storage ; water yield ; precipitation gradient ; Loess Plateau ; climate hazards ; geospatial analysis ; urban adaptation ; risk management ; snow disaster ; risk zoning ; Heilongjiang Province ; precipitation ; model resolutions ; cold region of China ; spatiotemporal distribution ; spatiotemporal variation ; 1961–2019 ; high-resolution and high-quality precipitation data ; independent and non-independent test ; the 0.01° multi-source fusion precipitation product ; extreme precipitation event ; forest types ; NDVI ; AVHRR GIMMS ; temperature range ; precipitation range ; snow cover ; black carbon concentration ; radiative forcing ; northeast China ; high temperature ; mobile phone data ; impact factor ; Zhuhai City ; WRF model ; projection ; short-lived heatwave event ; long-lived heatwave event ; Yangtze River Basin ; central and western Pacific ; thermocline ; yellowfin tuna ; CPUE ; El Niño ; La Niña ; GAM model ; spring soil moisture ; impact mechanism ; Songnen Plain ; Sanjiang Plain ; maize ; diurnal temperature range ; fresh air index ; natural microclimate comfort index ; fresh air–natural microclimate comfort index ; scenic spots ; Fujian province ; extreme climate indices ; temporal and spatial dynamics ; linear trend ; climate abrupt change ; central China ; peanut drought ; Shandong Province ; natural disaster risk assessment principles ; dry-hot wind disaster ; Shandong province ; natural disaster risk assessment principle ; summer maize ; inter- and mixed cropping ; flowering period ; yield ; potato climatic productivity potential ; Inner Mongolia ; effect ; human mobility ; rainfall ; taxi GPS data ; community ; Zhuhai central areas ; citrus ; quality ; future projection ; state-owned forest farms ; human resource allocation ; industrial structure ; coordination and adaptation ; personal structure ; contiguous poverty-stricken areas ; rainstorms and droughts ; direct economic losses ; disaster-affected population ; drought and flood ; vulnerability ; risk prediction ; agroecosystem ; heatwaves ; population exposure change ; global warming ; 1.5 °C warming scenario ; 2.0 °C warming scenario ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics
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  • 89
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: This Special Issue gathers papers reporting research on various aspects of remote sensing of Sea Surface Salinity (SSS) and the use of satellite SSS in oceanography. It includes contributions presenting improvements in empirical or theoretical radiative transfer models; mitigation techniques of external interference such as RFI and land contamination; comparisons and validation of remote sensing products with in situ observations; retrieval techniques for improved coastal SSS monitoring, high latitude SSS and the assessment of ocean interactions with the cryosphere; and data fusion techniques combining SSS with sea surface temperature (SST). New instrument technology for the future of SSS remote sensing is also presented.
    Keywords: Q1-390 ; n/a ; satellite salinity ; one-dimensional (1D) aperture synthesis radiometer ; smos ; Gulf of Maine ; retrieval errors ; Aquarius ; combined active/passive SSS retrieval algorithm ; ocean surface roughness ; upwelling ; salt transport ; quality assessment ; sea ice ; SMOS ; microwave radiometry ; Arctic Gateways ; Aquarius satellite ; validation ; sea surface temperature ; water transport ; forward model ; river discharge ; sea surface salinity ; remote sensing ; retrieval algorithm ; Water Cycle Observation Mission (WCOM) ; SMAP ; microwave remote sensing ; alboran sea ; surface velocity ; Arctic Ocean ; sea surface salinity (SSS) ; coastal ; brightness temperature (TB) ; interferometric microwave imager (IMI) ; Scotian Shelf ; MICAP ; different instrument configurations ; bias characteristics ; mediterranean sea ; Gulf of Mexico ; calibration ; retroflections ; Arctic ocean ; salinity ; Sea Surface Salinity ; Arctic rivers ; Argo ; data processing ; aquarius ; ocean salinity ; Aquarius Validation Data System (AVDS) ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 90
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-06-21
    Description: This reprint includes contributions from leaders in the field of personalized medicine in ophthalmology. The contributions are diverse and cover pre-clinical and clinical topics. We hope you enjoy reading the articles.
    Keywords: subthreshold micropulse laser ; 577-nm laser ; laser fixed parameters ; diabetic retinopathy ; diabetic macular edema ; optical coherence tomography ; autofluorescence ; real-life ; diabetic macular oedema ; visual prognosis ; indicators ; personalized medicine ; age-related macular degeneration ; choroidal neovascularization ; classification ; machine learning ; type 2 diabetes ; retinopathy ; ethnicity ; general practice ; risk factors ; progression ; glycemic gap ; glucose variability ; ETDRS classification ; biomarkers ; phenotypes ; anti-vascular endothelial growth factor ; diabetic retinopathy severity scale ; panretinal leakage index ; neovascular age-related macular degeneration ; anti-VEGF therapy ; retinal thickness ; visual acuity ; variability ; leakage index ; microaneurysms ; intravitreal aflibercept ; neovascularization ; ultra-widefield fluorescein angiography ; retinal imaging ; quantitative biomarkers ; precision medicine ; autoantibodies ; AT1-receptor ; PAR1 ; VEGF-A ; VEGF-B ; VEGF-receptor 2 ; AMD ; complement system ; semi-quantitative multiplex profilin ; mass spectrometry ; C4 ; vitronectin ; factor I ; genetic variants ; metabolites ; HDL ; central area thickness ; biomarker ; microRNA ; anti-VEGF ; retina ; edema ; OCT ; tomography ; microphysiological systems ; blood-neural barriers ; neurovascular unit ; disease modeling ; 3D models ; organ-on-a-chip ; inner blood-retinal barrier ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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  • 91
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Rapid establishment of seedlings in forest regeneration or afforestation sites after planting is a prerequisite for a successful reforestation. Seedling survival after outplanting can be improved by using high-quality seedling material. Seedling quality consists of several features, such as genetic source, morphological properties, nutritional status, stress resistance, and vitality of the seedlings. Field performance of the seedlings is a complex process which can be affected by many nursery and silvicultural practices. Nursery cultural practices strongly affect seedling quality, which is generally at its highest level during the growth period at the nursery. Afterwards, when the seedlings are transported from the nursery to the planting site (including seedling storage, handling, shipping, and planting practices), the quality of seedlings can only remain the same or decline. To ensure successful regeneration, it is important to produce seedlings that retain their high quality until planting, and to establish them quickly in the forest regeneration site.
    Keywords: Q1-390 ; container parameters ; forest regeneration material ; physiological attributes ; somatic embryogenesis ; Quercus rubra ; antioxidant enzymes ; nursery production ; shortleaf pine ; historical perspective ; maturation ; Appalachia ; bulk density ; Quercus robur L. ; rabbit ; western larch ; Picea abies L. Karst. ; sessile oak ; climate change ; physiological quality ; nursery culture ; Fennoscandia ; pedunculate oak ; elk ; seeds ; survival ; small mammal ; loblolly pine ; Norway spruce ; white oak ; growing media ; germination ; morphological attributes ; embling production ; mechanization ; browse ; contractor ; field performance ; reforestation ; white-tailed deer ; forest biotechnology ; cultural practice ; hybridization ; nutrients ; silviculture ; black locust ; scarification index ; seedling quality ; tree planting machine ; seed size ; herbicide ; artificial regeneration ; restoration ecology ; porosity ; northern red oak ; cryopreservation ; leaf senescence ; tree seedling ; Douglas fir ; Quercus ; growth ; mine reclamation ; forestry ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 92
    Publication Date: 2024-04-05
    Description: Ranaviruses and other viruses within the family Iridoviridae, infect a wide range of ecologically and commercially important ectothermic vertebrates, i.e., bony fish, amphibians, and reptiles, and invertebrates, including agricultural and medical pests and cultured shrimp and crayfish, and are responsible for considerable morbidity and mortality. Understanding the impact of these various agents on diverse host species requires the combined efforts of ecologists, veterinarians, pathologists, comparative immunologists and molecular virologists. Unfortunately, investigators involved in these studies often work in discipline-specific silos that preclude interaction with others whose insights and approaches are required to comprehensively address problems related to ranavirus/iridovirus disease. Our intent here is to breakdown these silos and provide a forum where diverse researchers with a common interest in ranavirus/iridovirus biology can profitably interact. As a colleague once quipped, “Three people make a genius.” We are hoping to do something along those lines by presenting a collection of research articles dealing with issues of anti-viral immunity, identification of a potentially novel viral genus exemplified by erythrocytic necrosis virus, viral inhibition of innate immunity, identification of novel hosts for lymphocystivirus and invertebrate iridoviruses, and modelling studies of ranavirus transmission. Collectively these and others will exemplify the breadth of ongoing studies focused on this virus family.
    Keywords: QH301-705.5 ; Q1-390 ; risk assessment ; n/a ; CQIV ; mathematical models ; amphibian ; iridovirus ; ISDL ; Exopalaemon carinicauda ; viral load ; virus isolation ; European chub ; outbreak ; Unconventional T cell ; early detection ; susceptible species ; viral immune evasion ; DNA virus ; Rana grylio virus ; antibody ; intracellular localization ; Rana grylio virus (RGV) ; British Columbia ; Iridoviridae ; Andrias davidianus ranavirus ; viral infection ; susceptible-infected (SI) models ; yeast two-hybrid (Y2H) ; prevalence ; host-pathogen interactions ; Pacific herring ; Procambarus clarkii ; Bayesian inference ; eDNA ; amphibians ; Artemia spp. ; ranavirosis ; cross-species transmission ; FV3 ; SHIV ; Gryllus bimaculatus ; Pacific salmon ; NF-?B ; cricket ; IIV-6 ; virus binding ; erythrocytic necrosis virus (ENV) ; envelope protein ; iridovirus core proteins ; emerging infection ; host ; Ranavirus ; white head ; Rana temporaria ; Imd ; biosecurity ; antiviral immunity ; Decapodiridovirus ; endemic disease ; Macrobrachium rosenbergii ; co-immunoprecipitation (Co-IP) ; Common frog ; aquatic animals ; virus surveillance ; immunomodulators ; frog virus 3 ; ELISA ; DIV1 ; megalocytivirus ; Lymphocystis disease virus ; bearded dragon ; susceptibility ; protein interaction ; Pogona vitticeps ; viral erythrocytic necrosis (VEN) ; histopathology ; epidemiology ; native-fish conservation ; viral transmission ; Sparus aurata ; immunohistochemistry ; lizard ; disease dynamics ; immunofluorescence ; transmission modelling ; Macrobrachium nipponense ; interferon ; nonclassical MHC ; heparan sulfate ; ranavirus ; Mexico ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 93
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: I am grateful to all the authors who contributed to this Special Issue and the referees for reviewing the manuscripts. Finally, I give my thanks to Ms. Alisa Si and all the editorial staff of Nanomaterials for their support during the publication of this Special Issue.
    Keywords: Si ; MnO2 ; rGO ; sea urchin-like structure ; lithium-ion battery ; high performance ; silica-based anode ; Ketjen Black ; electrochemical properties ; pseudocapacitor ; carbon nanotube ; polyaniline ; fractional-order circuit model ; memory effect ; fractional derivative ; zinc-ion batteries ; conducting polymers ; zinc-ion diffusion ; metal–organic framework ; supercapacitors ; energy density ; specific capacitance ; stability ; self-powered ; wearable flexible sensor ; energy harvesting ; human motion monitoring ; triboelectric nanogenerator ; NiMoO4@MnCo2O4 ; microstructure ; electrochemical performance ; cycling stability ; semiconductor superlattice ; dielectric capacity ; energy storage ; first-principles calculation ; supercapacitor ; organic crosslinked polymer ; porous carbon ; electrochemistry ; α-Fe2O3@MnO2 ; electrode materials ; flexibility ; hydrogen generation ; porous titanium oxide cage ; PtNi nanoparticles ; sodium borohydride hydrolysis ; NaBH4 ; graphene oxide ; catalytic activity ; hydrolysis ; aqueous zinc ion battery ; transition metal chalcogenides ; layered structure ; cathode ; energy storage mechanism ; g-C3N4 ; perovskite solar cells ; additive ; surface modifier layer ; Li-rich cathode material ; voltage and capacity fade ; testing mode ; cobalt-containing nanomaterials ; morphological design ; bio-derived hard carbon ; Coulomb efficiency ; Na-ion batteries ; storage mechanism ; fibrous phosphorus ; lithium-Ion battery ; anode ; CuMn2O4 ; nanosheet arrays ; hydrothermal ; battery-type ; CoO@rGO ; graphene ; MOF ; flexible electrodes ; hollow structure ; ultrafast integration ; lithium-ion batteries ; proton exchange membrane fuel cell ; mechanical vibration ; durability ; platinum migration ; accelerated stress test ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 94
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-05-06
    Description: Myxobacteria are fascinating and important prokaryotes. They have large genomes and exhibit a wide range of interesting behaviors, including multicellular fruiting body formation, social interaction, predation, and secondary metabolite production. Substantial progress is being made in understanding their ecological roles and the evolutionary forces that have shaped their phenotypes and behaviors. Novel species of myxobacteria are regularly described, often producing unusual metabolites and enzymes which can be of significant biotechnological interest. Molecular studies, ranging in subject from individual enzymes to entire ‘omes, continue to provide rich insights into myxobacterial biology. This collected volume brings together five research articles and three reviews, to provide a snapshot of current myxobacterial research in all its diversity.
    Keywords: carotenoids ; comparative genomics ; development ; fruiting body formation ; one-component systems ; quorum signalling ; two-component systems ; myxobacteria ; Myxococcales ; germination ; bacterial cell wall ; sporulation ; morphology ; photoreceptor ; photosensitizer ; photoregulation ; singlet oxygen ; plasmalogens ; CarF ; vitamin B12 ; CarH ; ECF-sigma ; CarD-CdnL ; microbial food web ; trophic interactions ; predator–prey interactions ; mesopredator ; social bacteria ; nematodes ; experimental community ; behavior ; Myxococcus sp. ; Corallococcus sp. ; Melittangium sp. ; Archangium sp. ; biosynthetic gene clusters ; Myxococcus xanthus ; phase contrast microscopy ; fluorescence microscopy ; aggregation ; rippling ; deep learning ; generative adversarial network ; pretator-prey coevolution ; antagonism ; mucoidy ; predatory bacteria ; bacterial predation ; prey diversity ; negative frequency dependence ; experimental evolution ; MyxoEE-6 ; functional genomics ; genome evolution ; genome organisation ; pan-genome ; proteomics ; taxonomy ; transcriptomics ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 95
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Land use is the projection of human activities in space, and it has become an important insight into the transformation and reconstruction of human society and economy. Rural land use in China is undergoing rapid transformation driven by the rapid development of science and technology. Effectively grasping the change and transformation process of rural land use and its internal mechanism provides an important reference for revealing the inherent laws of China's rural development. Rural land use is closely related to the rural vitalization strategy and urban–rural integration in the new era. An in-depth study of China's rural land use and policy reform provides the basis of knowledge for formulating and optimizing urban–rural relations. This Special Issue focuses on the changes, effects, and regulation of rural land use in China, focusing on its main contradictions and solutions, building a cooperative network and sharing platform for rural land use research from a multidisciplinary perspective, and further deepening the theoretical innovation and practical application of rural land use research. We invited scholars from various disciplines to contribute to the Special Issue, especially with papers on the subjects of theoretical innovation, technological innovation, and practical innovation in this field.
    Keywords: family farm ; efficiency ; DEA model ; Tobit model ; farm operation ; influencing factors ; soybean ; production pattern ; spatial agglomeration ; policy implications ; spatiotemporal changes ; crop planting structure ; black soil region ; Northeast China ; county-level ; geographic characteristics ; hollow village ; actor–network ; governance mode ; operation process ; appropriate tillage sand land ; land survey ; limiting factor ; land evaluation ; cultivated land protection ; Green Transition of Cultivated Land-use (GTCL) ; Water-Land-Food-Carbon (WLFC) ; coupling coordination ; land use change ; rural settlements ; spatial pattern evolution ; land policy ; China ; different modes ; land transfer ; livelihood capital ; difference-in-differences model ; Land Certificated Program (LCP) ; farmland “stickiness” ; land production function ; property rights ; agricultural policy ; cultivated land multifunctionality ; coupling coordination degree ; spatial-temporal pattern ; driving force ; major grain-producing areas ; northeast China ; comprehensive land consolidation ; pilot project ; decision-making evaluation ; farmers ; social investors ; non-agriculturalization rate ; ecological risk ; cultivated land change ; landform ; land management ; increasing versus decreasing balance (IVDB) ; balanced quota ; revenue ; inverted U-shaped curve ; Zhejiang province ; territorial space ; production–living–ecological space ; spatio-temporal variation ; eco-environment effect ; territorial spatial pattern ; eco-environmental quality ; soil contamination ; phytoremediation ; passivation ; farmer ; questionnaire survey ; paddy field ; dryland ; topographic gradient ; landscape characteristics ; land-use change ; rural settlement ; spatial distribution ; scale distribution ; morphological distribution ; the metropolitan fringe area ; Nanjing ; farmland transfer ; farmland function ; income structure ; rural household consumption ; consumption structure ; Yunnan Province ; farmers’ land transfer behavior ; herd effect ; geo-network ; the farmland right system reform ; creditor rights ; real rights ; agricultural modernization ; labor migration ; spatio-temporal evolution ; driving factor ; family structure ; heterogeneity ; area of land transfer ; rural–urban migration ; rural development ; land consolidation ; income distribution ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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  • 96
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: In the past 20 years, karst desertification control has produced remarkable results, and the South China karst has been a global hotspot for greening. However, in the new stage of karst desertification control, the functional lag of forest ecosystems and the insufficient supply capacity of ecosystem services are gradually becoming prominent. We not only lack systematic research on vulnerability and resilience, structure and stability, ecological assets and services, carrying capacity and ecological security, and service trade-offs/synergies and optimization in controlled ecosystems. There is still a lack of research on the ecological processes of newly constructed forests in improving ecosystem functions and services. Therefore, this reprint mainly focuses on the research improvement of forest ecosystem functions in karst desertification control. This includes the improvement mechanism of ecosystem structure, function, and services, the mechanism of ecosystem service tradeoff/synergy, and function optimization. An optimization model of ecosystem function and an improvement path for eco-product supply are introduced. The role of functional traits in the maintenance of ecological function and services is also established, and social–ecological responses to afforestation in karst desertification control are discussed.
    Keywords: structural trait ; element trait ; physiological trait ; leaf ; root ; karst ; ecosystem service supply ; value accounting ; eco-industry ; karst desertification environment ; farmland hydrological cycle ; agroforestry ; agronomic measures to water saving ; planting combinations ; investment strategy ; plant adaptability ; soil ; response ; biodiversity ; ecosystem services ; forests ; karst desertification ; plant functional traits ; structure ; landscape security pattern ; sensitivity ; landscape connectivity ; Guanling County ; Guizhou ; ecological products ; value realization ; ecological industry ; resilient landscape ; rural planning ; resilience assessment ; karst rocky desertification control areas ; karst forest ; vegetation water use strategy ; hydrogen and oxygen stable isotopes ; hydrologic niche separation ; principal component analysis ; redundancy analysis ; karst rocky desertification area ; species diversity ; evaluation indicator systems ; fuzzy integrated evaluation ; karst spring ; dissolved organic carbon/nitrogen ; rocky desertification ; terrestrial ecosystem ; soil aggregate stability ; soil nutrients ; vegetation restoration ; karst rocky desertification ; forest ; karst desertification control ; loquat ; intercropping peanut ; N2O emission ; Abies fanjingshanensis ; microbial carbon use efficiency ; physicochemical indices ; bacteria ; fungus ; structural optimization ; water and fertilizer regulation ; functional improvement ; forests ecosystem ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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  • 97
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: It is currently apparent that extracellular ATP's physiological effect is mediated by its interaction with specific purinergic receptors. All purinergic receptors are divided into P1-purinoreceptors and P2-purinoreceptors. Each of the subtypes is divided into a number of families. For instance, P2 receptors are divided into P2X and P2Y receptors according to the mechanism by which their effect is realized: P2Y are G-protein-coupled receptors, while P2X receptors are ligand-operated ion channels. P2X receptors are important molecular therapeutic targets, the malfunctioning of which leads to severe complications in the physiology of humans and animals and causes dangerous diseases. The search for compounds that can modulate the function of purinergic receptors can lead to the creation of new drugs that are effective in central and peripheral nervous system and immune system disease treatment, including neuroinflammation, hypoxia/ischemia, epilepsy and neuropathic pain. In this Special Issue, we wish to offer a platform for high-quality publications on the latest advances in the identification of P2X/Y- and P1-receptor blockers, functions and regulation by them; the characterization of these receptor signaling networks and crosstalk; mechanisms underlying the role of purinoceptors in neurodegenerative illnesses as well as chronic neuronal changes following acute noxious damage and therapeutic opportunities associated with regulation of purinergic receptor activity.
    Keywords: adenosine receptors ; adipogenesis ; osteogenesis ; adipose tissue ; bone marrow ; obesity ; neonatal seizures ; development ; ATP ; purinergic signalling ; P2X7 receptor ; endometriosis ; adenosine ; P2Y ; P2X ; ectonucleotidases ; pain ; inflammation ; endometrium ; CD73 ; CD39 ; P2Y2 receptor ; P2X4 receptor ; canine ; dog ; DH82 ; macrophage ; neuroinflammation ; antinociception ; cerebral ischemia ; oxygen-glucose deprivation ; A2B receptors ; oligodendrocyte differentiation ; demyelination ; retina ; purinergic modulation ; glycinergic neurotransmission ; microglia ; neurodegeneration ; glycine transporters ; guanosine ; stroke ; neuroprotection ; purinergic signaling ; purinergic receptors ; autoimmune disease ; astroglia ; G protein-coupled receptor 17 (GPR17) ; neurite outgrowth ; montelukast ; NG2 ; ex vivo organotypic brain slice co-culture ; neurodegeneration and neuroregeneration ; n/a ; macrophages ; P2X7R ; pore formation ; inflammasome activation ; inflammatory diseases ; gallic acid ; visceral pain ; depression ; hippocampus ; spinal cord ; dorsal root ganglion ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 98
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: One last comment concerns the fundamental contributions of Fourier analysis to quantum physics: Quantum mechanics and quantum field theory.
    Keywords: Q1-390 ; self-electrorefining ; hedyphane group ; structural combinatorics ; CuFe2O4 ; Kamchatka ; Raman ; El Dragón ; apatite supergroup ; borate ; ariegilatite ; oyonite ; Tuscany ; gahnite ; magnesioferrite ; Szklary pegmatite ; aurihydrargyrumite ; Au6Hg5 phase ; Trentino ; Peru ; Germany ; cerromojonite ; sulfosalt ; pyrometamorphism ; Bellerberg volcano ; manganese ; gold ; spinel supergroup ; selenium ; CuAl2O4 ; clinokurchatovite ; sharyginite ; Poland ; copper ; kurchatovite ; copper oxide ; antimony ; nabimusaite group ; laachite ; lead ; thermaerogenite ; intercalated hexagonal antiperovskite ; placer ; Lower Silesia ; Eldfell ; Tolbachik volcano ; structural complexity ; nöggerathite-(Ce) ; Val di Fiemme ; Oyon district ; sanidinite ; cuprospinel ; sulfate ; fumarole sublimate ; Cretaio ; polymorphism ; polytypism ; tiberiobardiite ; fiemmeite ; stacking faults ; CO3-group ; Hatrurim Complex ; least-action principle ; phosphorus ; Laacher See ; new oxalate mineral ; Japan ; verneite ; alkaline volcanic rock ; arsenic ; Raman spectroscopy ; single-crystal investigation ; Rusinovite ; Eifel ; Lima department ; Italy ; barioferrite ; configurational entropy ; Hekla ; mercury ; Bolivia ; parafiniukite ; aluminofluoride ; new mineral ; Shadil-Khokh volcano ; Vesuvius ; bournonite group ; Ehime ; calcium ; lillianite homologous series ; chalcophyllite group ; sou?ekite ; silicate ; pyrometamorphic rocks ; crystal structure ; zirconolite ; bismuth ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 99
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: The reprint provides the most relevant and state-of-the-art in the field, including recent developments in the production of natural compounds from various bioresources, and their formulations as bioactives. This reprint also covered the engineered approaches for enhanced biological properties and their potential applications. Identification of novel compounds and bioprocess tools to improve the quantity and quality of bioactive compounds and their formulations are exclusively covered in this reprint.
    Keywords: anti-solvent ; enzymatic saccharification ; EMIM-Ac ; ethanol ; ionic liquid ; lignocellulosic biomass ; recycling ; agro-industry ; microencapsulation ; bioactive compounds ; in vitro digestion ; yogurt ; cannabis ; cannabinoids ; postharvest ; drying ; curing ; storage ; biosynthesis ; pre-treatments ; sorption isotherm ; Raphanus sativus L. ; recombinant IFN-α2a ; apoptosis ; antiviral and antitumor activity ; Japanese knotweed rhizome bark ; SARS-CoV-2 ; COVID-19 ; virus neutralization test ; nano-formulation ; nutraceuticals ; prebiotics ; nanofabricated delivery system ; liposomes ; nano-emulsions ; Abelmoschus manihot ; neurodegenerative disease ; oxidative stress ; proliferation ; inflammation ; nucleotide excision repair ; Actinosynnema pretiosum ; ansamitocin P-3 ; ssgA ; AdpA ; morphological differentiation ; pomegranate ; pomace ; extraction ; biological activity ; functional beverages ; sensory quality ; vitamins ; formulation ; homogeneous systems ; hydrophile–lipophile balance ; Emblica officinalis ; phytochemicals ; hyperlipidemia ; pharmacology ; nanoformulation ; Prunus mume ; vasorelaxant ; hypertension ; angiotensin receptor blockers ; agro-waste ; valorization ; value-added bioproducts ; micro/nano encapsulation ; agri-food-pharma applications ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 100
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: The papers published in this Special Issue report on recent studies investigating the exploitation of by-products produced by the food industry. The topics investigated include the extraction setups used for valuable food waste by-products and their applications as adjuncts to food preparation; the appropriate selection of solvents and extraction processes; and the interactions between extracted fractions and supplementary foods. The papers evaluate a wide variety of foodstuffs and provide results regarding the extension their shelf-lives and activities as functional foods.
    Keywords: by-product ; rheological properties ; optimization ; melting profile ; antioxidant activity ; mayonnaise ; olive mill wastewater ; oxidative stability ; phenolic extract ; pork ; fatty acid ; amino acid ; mineral ; meat ; sustainability ; spent biomass ; prebiotic potential ; enzymatic digestion ; biorefinery ; circular economy ; by-products ; ovine scotta ; bioactive peptides ; bromelain ; pancreatin ; dipeptidyl peptidase IV inhibition ; ovine second whey cheese ; enzymatic hydrolysis ; wasted bread ; bioprocessing ; lactic acid bacteria ; soil amendment ; byproducts ; vegetable oil industry ; phenolics ; flavonoids ; photochemiluminescence ; cold-pressed oil by-product ; gum ; thixotropic behavior ; low-fat vegan mayonnaise ; thickeners ; gelling agents ; tomato pomace ; lycopene ; β-carotene ; extraction ; food by-products ; deep eutectic solvents ; non-thermal drying ; stilbene ; vine shoots ; viticulture waste ; trans-resveratrol ; ε-viniferin ; Italian varieties ; no-waste ; omega-3 ; smart sensors ; reuse ; fish oil industry ; recovery ; chemometrics ; lipid profile ; aquafaba ; cold-pressed oils ; confocal laser scanning microscopy ; egg replacement ; physicochemical properties ; radical scavenging activity ; vegan mayonnaise ; Amberlite resin ; hazelnut skin ; polyphenols ; Pinot noir pomace ; solid–liquid extraction ; valorization ; fatty acids ; derivatization ; cranberry pomace ; dietary fiber ; technological properties ; kiwi byproducts ; probiotic ; prebiotic ; Lactobacillus casei ; ingredients ; functional foods ; microbial spoilage ; lipidic oxidation ; antioxidant ; predictive microbiology ; food preservation ; food safety ; sustainable strategy ; by-product reuse ; kinetic parameters ; Olea europaea ; waste reuse ; inulin ; high polymerization degree ; functional pasta ; glycemic index ; prebiotics growth ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
    Language: English
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