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  • thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science  (12)
  • Sound production
  • Springer International Publishing  (13)
  • Annual Reviews  (1)
  • Nature Publishing Group
  • 2020-2024  (13)
  • 2005-2009  (1)
  • 1990-1994
  • 1980-1984
  • 1960-1964
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  • 2020-2024  (13)
  • 2005-2009  (1)
  • 1990-1994
  • 1980-1984
  • 1960-1964
Year
  • 1
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-11
    Description: This open access book gathers original contributions focused on the transition of the European steel industry to Industry 4.0. It not only investigates how Industry 4.0 can enhance productivity, cost-saving, and sustainability in the steel industry but also helps to comprehend its broad consequences on employment, education and training, human resources, economic resilience and decarbonisation. The content engages with the international debate on Industry 4.0 through the lens of the steel industry from a multidisciplinary perspective. It encourages a scientifically grounded critical approach and includes contributions from humanities and technical disciplines, with a focus on the social dimensions of the phenomenon. This book draws strength from up-to-date international research projects and adopts a strong industry-based perspective, providing a thorough description and analysis of the state of the art of the European steel industry. It also analyzes the trends, outcomes, opportunities, and criticalities arising with the transition to the Industry 4.0 paradigm. The book is primarily based on the results of the European Steel Skills Agenda (ESSA) skills alliance project co-funded by the Erasmus+ programme of the European Union and supported by the European Steel Technology Platform (ESTEP). This is an open access book.
    Keywords: Industry 4.0 ; Steel Industry ; Skill Formation ; Recruitment ; Technological Innovation ; Workforce Development ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 2
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-01
    Description: This open access book offers a timely and comprehensive review of the field of neurotronics. Gathering cutting-edge contributions from neuroscientists, biologists, psychologists, as well as physicists, microelectronics engineers and information scientists, it gives extensive information on fundamental information pathways in selected nervous systems. It also highlights their relevance as building blocks for novel computing architectures, such as bio-inspired electronic devices, neuromorphic architectures, memristive devices, adaptive sensors and emergent, pulsed-coupled oscillatory networks. All in all, this book offers a unique bridge between fundamental research in neuroscience, neural information processing, nonlinear dynamics, and self-organization, and advanced practical applications concerning the fabrication of hardware-oriented computing.
    Keywords: Neuromorphic Computing ; Self-assembled Networks ; Oscillator Networks ; Simulation of Memristive Devices ; Hippocampal Learning Models ; Artificial Synapse ; Neuronal Synchrony ; Memristive and Memsensor Devices ; Bio-inspired Electronics ; Bio-inspired Decision Making Systems ; Smart Sensor Arrays ; Neuromorphic Sensing ; CRC 1461 ; thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 3
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-11
    Description: This seminal compendium, available through open access, illuminates the forefront of digital collaboration in production. It introduces the visionary concept of the Internet of Production (IoP), an ambitious initiative by Germany's esteemed Cluster of Excellence at RWTH Aachen University. This handbook pioneers the integration of data, models, and knowledge across development, production, and user cycles, offering interdisciplinary insights into production technology's horizons with the overall objective to create a worldwide lab. The work is organized into seven key parts, each contributing to a comprehensive understanding of the IoP. Part I lays the foundation with interdisciplinary visions and concepts. Part II delves into IoP's infrastructure, encompassing digital shadows and actionable artificial intelligence. Part III examines materials within the digitalized production landscape. Part IV confronts the challenges and potentials of production processes under novel digitalization methods. Part V focuses on production management with data-driven decision support, while Part VI explores agile development processes. Finally, Part VII delves into the interplay between internal and external perspectives in the IoP, human-centered work design, and platform-based ecosystems. Supported by the German Research Foundation (DFG), this compendium redefines manufacturing through the transformative IoP lens. Embrace this scholarly endeavor to embrace technological advancement. This is an open access book.
    Keywords: Internet of Production ; Industrial Internet of Things ; Advanced Manufacturing ; Production ; Digital Shadow ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGP Production and industrial engineering ; thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMB Algorithms and data structures ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas::KJMV5 Production and quality control management ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas::KJMV8 Purchasing and supply management
    Language: English
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  • 4
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-11
    Description: This open access book comprehensively consolidates studies in the rapidly emerging field of battery management. The primary focus is to overview the new and emerging data science technologies for full-lifespan management of Li-ion batteries, which are categorized into three groups, namely (i) battery manufacturing management, (ii) battery operation management, and (iii) battery reutilization management. The key challenges, future trends as well as promising data-science technologies to further improve this research field are discussed. As battery full-lifespan (manufacturing, operation, and reutilization) management is a hot research topic in both energy and AI fields and none specific book has focused on systematically describing this particular from a data science perspective before, this book can attract the attention of academics, scientists, engineers, and practitioners. It is useful as a reference book for students and graduates working in related fields. Specifically, the audience could not only get the basics of battery manufacturing, operation, and reutilization but also the information of related data-science technologies. The step-by-step guidance, comprehensive introduction, and case studies to the topic make it accessible to audiences of different levels, from graduates to experienced engineers.
    Keywords: Lithium-ion Battery ; Battery Manufacturing Management ; Battery Operation Management ; Battery Recycling Management ; Data Science ; Artificial Intelligence ; Open Access ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::U Computing and Information Technology::UN Databases ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering
    Language: English
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  • 5
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-05
    Description: This open-access book empowers its readers to explore the acoustic world of animals. By listening to the sounds of nature, we can study animal behavior, distribution, and demographics; their habitat characteristics and needs; and the effects of noise. Sound recording is an efficient and affordable tool, independent of daylight and weather; and recorders may be left in place for many months at a time, continuously collecting data on animals and their environment. This book builds the skills and knowledge necessary to collect and interpret acoustic data from terrestrial and marine environments. Beginning with a history of sound recording, the chapters provide an overview of off-the-shelf recording equipment and analysis tools (including automated signal detectors and statistical methods); audiometric methods; acoustic terminology, quantities, and units; sound propagation in air and under water; soundscapes of terrestrial and marine habitats; animal acoustic and vibrational communication; echolocation; and the effects of noise. This book will be useful to students and researchers of animal ecology who wish to add acoustics to their toolbox, as well as to environmental managers in industry and government.
    Keywords: Animal Communication ; Bioacoustics ; Echolocation ; Hearing ; Sound production ; Vocalization ; Biotremology ; Syrinx ; Anthropogenic noise ; Mate choice ; Stridulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences ; thema EDItEUR::P Mathematics and Science::PH Physics::PHD Classical mechanics::PHDS Wave mechanics (vibration and acoustics) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTA Acoustic and sound engineering ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences ; thema EDItEUR::P Mathematics and Science::PH Physics::PHD Classical mechanics::PHDS Wave mechanics (vibration and acoustics) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTA Acoustic and sound engineering
    Language: English
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  • 6
    Publication Date: 2024-04-05
    Description: This open access book presents a thorough look at tortuosity and microstructure effects in porous materials. The book delivers a comprehensive review of the subject, summarizing all key results in the field with respect to the underlying theories, empirical data available in the literature, modern methodologies and calculation approaches, and quantitative relationships between microscopic and macroscopic properties. It thoroughly discusses up to 20 different types of tortuosity and introduces a new classification scheme and nomenclature based on direct geometric tortuosities, indirect physics-based tortuosities, and mixed tortuosities (geometric and physics-based). The book also covers recent progress in 3D imaging and image modeling for studying novel aspects of tortuosity and associated transport properties in materials, while providing a comprehensive list of available software packages for practitioners in the community. This book is a must-read for researchers and students in materials science and engineering interested in a deeper understanding of microstructure–property relationships in porous materials. For energy materials in particular, such as lithium-ion batteries, tortuosity is a key microstructural parameter that can greatly impact long-term material performance. Thus, the information laid out in this book will also greatly benefit researchers interested in computational modeling and design of next-generation materials, especially those for sustainability and energy applications.
    Keywords: Tortuosity of Materials ; Effective Transport Properties of Porous Media ; Microstructure-Property Relationships ; Digital Materials Design ; Simulation of Transport Properties ; Integrated Computational Materials Engineering ; Virtual Materials Testing ; Engineered Porous Materials ; Tortuosity-Porosity Relationships ; Diffusion in Porous Materials ; 3D Imaging ; X-Ray Tomography for Materials ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::P Mathematics and Science::PH Physics::PHU Mathematical physics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science::TGMB Engineering thermodynamics
    Language: English
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  • 7
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-11
    Description: This open access book presents the findings of Collaborative Research Center Transregio 40 (TRR40), initiated in July 2008 and funded by the German Research Foundation (DFG). Gathering innovative design concepts for thrust chambers and nozzles, as well as cutting-edge methods of aft-body flow control and propulsion-component cooling, it brings together fundamental research undertaken at universities, testing carried out at the German Aerospace Center (DLR) and industrial developments from the ArianeGroup. With a particular focus on heat transfer analyses and novel cooling concepts for thermally highly loaded structures, the book highlights the aft-body flow of the space transportation system and its interaction with the nozzle flow, which are especially critical during the early phase of atmospheric ascent. Moreover, it describes virtual demonstrators for combustion chambers and nozzles, and discusses their industrial applicability. As such, it is a timely resource for researchers, graduate students and practitioners.
    Keywords: Engineering Fluid Dynamics ; Aerospace Technology and Astronautics ; Structural Materials ; Rocket Propulsion ; Multi-scale Modelling in Aerospace ; Real-gas Thermodynamics ; Multi-phase Flow Simulation ; Compressible Shear-layer ; Turbulent Heat Flux Model ; LOX/CH4 Combustor ; Multi-element Combustor Chamber ; Wall Heat Transfer Prediction ; SFB/TRR40 ; Open Access ; Mechanics of fluids ; Aerospace & aviation technology ; Astronautics ; Materials science ; Structural engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science::TGMF Engineering: Mechanics of fluids ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TR Transport technology and trades::TRP Aerospace and aviation technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 8
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-03
    Description: This book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background information and also tackles animal models in NTD therapeutics research. By bringing together state-of-the-art expert knowledge, the book contributes to the aim of ultimately ending the epidemics of neglected tropical diseases, complying with UN Sustainable Development Goal 3, Health and Well-Being. The volume highlights the activities of the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD pAThogEns), funded by the Medical Research Council in the UK. The four NTDs discussed in the book were selected as these are in the focus of VALIDATE’s research. The book targets scientists and clinicians working on NTDs, as well as all readers with a background in biomedicine and interest in vaccine development. This is an open access book.
    Keywords: leishmaniasis ; neglected tropical disease ; Tuberculosis ; biomarkers ; Leprosy ; melioidosis ; Buruli ulcer disease ; infectious disease treatment ; vaccine development ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology
    Language: English
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  • 9
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-11
    Description: This open access book provides a totally new perspective on the rapidly developing sector of electrochemical energy storage, putting a spotlight on their sustainability under consideration of the latest developments and emerging future technologies. A number of selected, high-level authors from different disciplines discuss the potential contribution of batteries to a cleaner society, the need for new battery concepts, necessary new chemistries and their sustainability. These include not only analyses of the most relevant technological developments in the field, but also the latest state of knowledge in terms of their applicative functionalities in transport and stationary applications within the clean energy transition framework, their potential environmental impacts, resource demands and social impacts, and the corresponding methodological advances. All these aspects are analyzed on micro-level (i.e., for the specific technology), but also on macro-scale i.e., from a systemic perspective, providing a glimpse on how emerging battery systems might cover future energy storage demand. By taking a prospective and interdisciplinary viewpoint, this book will be of interest for a broad field of readers interested in electrochemistry, engineering with particular focus on electric grids and on-board systems and energy system analysis, but also those worried about the sustainability and societal challenges related with the energy transition(s).
    Keywords: Energy Storage ; Electrochemical energy storage ; large-scale energy storage ; energy storage for de-carbonization ; emerging batteries ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THV Alternative and renewable energy sources and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering::THV Alternative and renewable energy sources and technology
    Language: English
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  • 10
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-03-23
    Description: This open access book includes detail on various structures, buildings, and building materials from different structural and sustainability perspectives. It describes how the building industry is vital for the achievement of the sustainable development goals, namely, economic growth, social progress, and the effective protection of the environment. The aim of this collection is to foster the design and construction of sustainable structures and buildings to reduce the environmental load, connect with the environment, and benefit the health of occupants. Presenting the knowledge, trends, and developments from a group of contributors in the field working with different kinds of structures, structural components, buildings, and building materials, the book is ideal for practitioners working in commercial settings, as well as engineering students and researchers concerned with sustainability issues.
    Keywords: Sustainable structures ; structural engineering ; energy efficiency ; sustanable cities ; sustainable materials ; thema EDItEUR::A The Arts::AM Architecture::AMC Architectural structure and design::AMCR Environmentally-friendly (‘green’) architecture and design ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TN Civil engineering, surveying and building::TNK Building construction and materials ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNU Sustainability
    Language: English
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  • 11
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-11
    Description: This open access book offers a host of theoretical knowledge at the basis of new EM&Ts (namely, Interactive Connected Smart Materials, Wearables (ICS), Nanomaterials, Advanced Growing Materials, and Experimental Wood-Based Materials), as communicated through the unique design teaching method developed within the context of the European Project DATEMATS, a result of the creative workshops held by the four higher education institutions that were partners in the project, stressing the pros and cons of the method and offering ideas for further development and improvement. The modern age requires its own innovations in regards to both social and industrial progress, innovations made possible by Emerging Materials and Technologies (EM&Ts). Frameworks for designing both with and for the new materials are presented, educating designers about the opportunities offered by EM&Ts and how to take advantage of them. At the same time, the book explains how the method developed through the knowledge generated at research centers and universities can be communicated to companies across various industries that stand to gain from it, linking the assorted stakeholders, and includes a final chapter based on feedback from both students and business professionals as to the benefits of academic/industrial cooperation. This is an open access book.
    Keywords: ICS Materials ; Nanomaterials ; Nanoscale Structures ; Experimental Wood-based Materials ; Advanced growing Materials ; Methodological Approach in Design Process ; Innovative Products and Services in EM&T ; Materials in Product Design Education ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science ; thema EDItEUR::J Society and Social Sciences::JN Education::JNU Teaching of a specific subject ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBD Technical design ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBN Nanotechnology
    Language: English
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  • 12
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    Springer Nature | Springer International Publishing
    Publication Date: 2024-04-11
    Description: This open access book provides an overview of the work undertaken within the FiberEUse project, which developed solutions enhancing the profitability of composite recycling and reuse in value-added products, with a cross-sectorial approach. Glass and carbon fiber reinforced polymers, or composites, are increasingly used as structural materials in many manufacturing sectors like transport, constructions and energy due to their better lightweight and corrosion resistance compared to metals. However, composite recycling is still a challenge since no significant added value in the recycling and reprocessing of composites is demonstrated. FiberEUse developed innovative solutions and business models towards sustainable Circular Economy solutions for post-use composite-made products. Three strategies are presented, namely mechanical recycling of short fibers, thermal recycling of long fibers and modular car parts design for sustainable disassembly and remanufacturing. The validation of the FiberEUse approach within eight industrial demonstrators shows the potentials towards new Circular Economy value-chains for composite materials.
    Keywords: FiberEUse project ; composite recycling ; remanufacturing ; demanufacturing processes ; composite reformulation ; Composite repair ; value-chain integration ; Co-design of creative products ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGP Production and industrial engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TH Energy technology and engineering ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNU Sustainability ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 13
    Publication Date: 2024-04-11
    Description: This open access book gathers authoritative contributions concerning multiscale problems in biomechanics, geomechanics, materials science and tribology. It is written in memory of Sergey Grigorievich Psakhie to feature various aspects of his multifaceted research interests, ranging from theoretical physics, computer modeling of materials and material characterization at the atomic scale, to applications in space industry, medicine and geotectonics, and including organizational, psychological and philosophical aspects of scientific research and teaching as well. This book covers new advances relating to orthopedic implants, concerning the physiological, tribological and materials aspects of their behavior; medical and geological applications of permeable fluid-saturated materials; earthquake dynamics together with aspects relating to their managed and gentle release; lubrication, wear and material transfer in natural and artificial joints; material research in manufacturing processes; hard-soft matter interaction, including adhesive and capillary effects; using nanostructures for influencing living cells and for cancer treatment; manufacturing of surfaces with desired properties; self-organization of hierarchical structures during plastic deformation and thermal treatment; mechanics of composites and coatings; and many more. Covering established knowledge as well as new models and methods, this book provides readers with a comprehensive overview of the field, yet also with extensive details on each single topic.
    Keywords: Solid Mechanics ; Biomedical Engineering and Bioengineering ; Biomaterials ; Biomechanical Analysis and Modeling ; Nanomedicine and Nanotoxicology ; Biological Effects of Nanomaterials ; Cell–nanomaterial Interactions ; Bone Tissue Fracture ; Biomechanical Aspects of Joint Arthroplasty ; Resurfacing Endoprosthesis ; Two-phase Lubrication of Biological Joints ; Mechanics of Earthquakes ; Active Control of Tectonics ; Fracture Processes in Rock ; Multiscale Problems in Tribology ; Hierarchically Organized Structures ; Adhesive Contacts ; Friction Stir Processing ; Particle-based Discrete Element Method ; Low-dimensional Aluminum (Hydro)Oxides ; Nanostructures in Cancer Treatment ; Lattice Curvature ; Wear Resistance ; Open Access ; Mechanics of solids ; Biomedical engineering ; Materials science ; Biotechnology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science::TGMD Engineering: Mechanics of solids ; thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services::MQW Biomedical engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 14
    Publication Date: 2022-05-25
    Description: First published online as a Review in Advance on October 24, 2005. (Some corrections may occur before final publication online and in print)
    Description: Author Posting. © Annual Reviews, 2005. This article is posted here by permission of Annual Reviews for personal use, not for redistribution. The definitive version was published in Annual Review of Physiology 68 (2006): 22.1-22.29, doi:10.1146/annurev.physiol.68.040104.105418.
    Description: Superfast muscles of vertebrates power sound production. The fastest, the swimbladder muscle of toadfish, generates mechanical power at frequencies in excess of 200 Hz. To operate at these frequencies, the speed of relaxation has had to increase approximately 50-fold. This increase is accomplished by modifications of three kinetic traits: (a) a fast calcium transient due to extremely high concentration of sarcoplasmic reticulum (SR)-Ca2+ pumps and parvalbumin, (b) fast off-rate of Ca2+ from troponin C due to an alteration in troponin, and (c) fast cross-bridge detachment rate constant (g, 50 times faster than that in rabbit fast-twitch muscle) due to an alteration in myosin. Although these three modifications permit swimbladder muscle to generate mechanical work at high frequencies (where locomotor muscles cannot), it comes with a cost: The high g causes a large reduction in attached force-generating cross-bridges, making the swimbladder incapable of powering low-frequency locomotory movements. Hence the locomotory and sound-producing muscles have mutually exclusive designs.
    Description: This work was made possible by support from NIH grants AR38404 and AR46125 as well as the University of Pennsylvania Research Foundation.
    Keywords: Parvalbumin ; Ca2+ release ; Ca2+ uptake ; Cross-bridges ; Adaptation ; Sound production ; Whitman Center
    Repository Name: Woods Hole Open Access Server
    Type: Article
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