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  • Other Sources  (6)
  • American Meteorological Society
  • Springer Nature
  • Taylor & Francis
  • 2020-2022  (5)
  • 1890-1899  (1)
  • 1
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    Taylor & Francis
    In:  The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, 36 (222). pp. 430-437.
    Publication Date: 2019-05-14
    Type: Article , PeerReviewed
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  • 2
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    Taylor & Francis
    In:  Critical Reviews in Biotechnology . pp. 1-14.
    Publication Date: 2021-01-08
    Description: The marine environment encompasses a huge biological diversity and can be considered as an underexplored location for prospecting bioactive molecules. In this review, the current state of art about antimicrobial molecules from marine bacteria has been summarized considering the main phylum and sources evolved in a marine environment. Considering the last two decades, we have found as most studied group of bacteria producers of substances with antimicrobial activity is the Firmicutes phylum, in particular strains of the Bacillus genus. The reason for that can be attributed to the difficult cultivation of typical Actinobacteria from a marine sediment, whose members are the major producers of antimicrobial substances in land environments. However, a reversed trend has been observed in recent years with an increasing number of reports settling on Actinobacteria. Great diversity of chemical structures have been identified, such as fijimicyns and lynamicyns from Actinomycetes and macrolactins produced by Bacillus.
    Type: Article , PeerReviewed
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  • 3
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    Taylor & Francis
    In:  Expert Opinion on Drug Discovery, 15 (4). pp. 499-522.
    Publication Date: 2021-01-08
    Description: Introduction: The marine environment is a very promising resource for natural product research, with many of these reaching the market as new drugs, especially in the field of cancer therapy as well as the drug discovery pipeline for new antimicrobials. Exploitation for bioactive marine compounds with unique structures and novel bioactivity such as the isoquinoline alkaloid; trabectedin, the polyether macrolide; halichondrin B, and the peptide; dolastatin 10, requires the use of analytical techniques, which can generate unbiased, quantitative, and qualitative data to benefit the biodiscovery process. Metabolomics has shown to bridge this understanding and facilitate the development of new potential drugs from marine sources and particularly their microbial symbionts. Areas covered: In this review, articles on applied secondary metabolomics ranging from 1990–2018 as well as to the last quarter of 2019 were probed to investigate the impact of metabolomics on drug discovery for new antibiotics and cancer treatment. Expert opinion: The current literature review highlighted the effectiveness of metabolomics in the study of targeting biologically active secondary metabolites from marine sources for optimized discovery of potential new natural products to be made accessible to a R&D pipeline.
    Type: Article , PeerReviewed
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  • 4
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    Taylor & Francis
    In:  Critical Reviews in Environmental Science and Technology . pp. 1-52.
    Publication Date: 2021-06-25
    Description: Traceability and reliable results are the two pillars of analytical methods; certified reference materials (CRMs) meet this requirement. ISO 17034:2016 credentials provide brief information on general requirements for the competence of Reference Material Producers (RMPs). The different types of CRMs have been produced in recent years for chemical analysis in food, water, soil, and sediment matrices in recent years. This review provides a detailed overview of the development of CRMs in the field of marine environment, as matrix CRMs play an important role in the field of environmental monitoring. COMAR database, EVISA database: materials, LGC standards, and JRC catalogs are very helpful online resources to find various types of CRMs according to the application requirements. Highlights - The classification of certified reference materials (CRMs) in the field of marine environment is presented; - General information about the production and characteristics of CRMs is discussed; - Examples of use of existing marine CRMs are described in detail; - Importance of CRMs for QA/QC and CRMs development for chemical analysis is presented; - The parameters that characterize the CRMs: representativeness, homogeneity, stability, and certified value are provided.
    Type: Article , PeerReviewed
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  • 5
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    Springer Nature
    In:  In: Encyclopedia of Solid Earth Geophysics. , ed. by Gupta, H. Encyclopedia of Earth Sciences Series . Springer Nature, Cham, Switzerland, , 11 pp. ISBN 978-3-030-10475-7
    Publication Date: 2021-02-10
    Description: The Trans-European Suture Zone (TESZ) is the transition zone from the Precambrian East European Craton in the north and east to the younger Phanerozoic mobile belts to the south and west. It is the most prominent lithospheric tectonic feature of Europe. The term Trans-European Suture Zone was only adapted around year 2000 during the Pan-European EUROPROBE program of the European Science Foundation. Until then, parts of the zone were termed Teisseyre-Tornquist Zone, Sorgenfrei-Tornquist Zone, Trans-European Fault, and Tornquist Fan.
    Type: Book chapter , NonPeerReviewed
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  • 6
    Publication Date: 2021-01-08
    Description: Freshwater sponges can be considered a promising new source of bioactive compounds for the pharmaceutical industry; however, the research on their chemical composition is still in the incipient stage. We evaluated the most endemic Amazonian freshwater sponge species from the Drulia and Metania genera by untargeted metabolomic approaches, based on UHPCL-HRMS, in order to identify chemical markers and explore the diversity of specialized metabolites. The use of untargeted approaches allowed us to observe subsets of metabolites that enabled the characterization of, not only each genus, but also, of each species. Freshwater sponge species presented themselves as rich sources of fatty acids and sterols, which were putatively identified. These metabolites were suggested as chemical markers for further targeted metabolomic studies.
    Type: Article , PeerReviewed
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