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  • thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics  (46)
  • thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy  (38)
  • Chemistry
  • Life and Medical Sciences
  • IntechOpen  (105)
  • 2020-2024  (105)
  • 1950-1954
  • 1945-1949
  • 2023  (105)
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  • 2020-2024  (105)
  • 1950-1954
  • 1945-1949
Year
  • 1
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Mineralogy includes thirteen chapters that discuss the methodology of specific mineralogical methods, the composition of minerals from different igneous rocks, and the composition of minerals from different sedimentary rocks.It contains detailed mineralogical studies from Africa, Asia, and Europe. Chapters present different scientific mineralogical methods and detailed descriptions of minerals from different magmatic and sedimentary rocks.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNV Chemistry of minerals, crystals and gems
    Language: English
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  • 2
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Benzimidazole is a comprehensive survey of the known and new methods of benzimidazole synthesis, the spectral and theoretical aspects of existing benzimidazole derivatives, and the anticancer properties of a new class of benzimidazole derivatives. This book examines aspects and newer mechanisms of benzimidazoles containing heterocyclic moiety. Chapters report on anticancer properties of benzimidazole derivatives, novel methods of synthesis of benzimidazoles, versatile nature of the benzimidazoles, spectral and theoretical studies of benzimidazole derivatives, and medicinal importance and pharmacological aspects of benzimidazole derivatives.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 3
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: The objective of this Genetic Polymorphisms book is to rehighlight and provide few updates on the role of genetic polymorphisms in medicine and agriculture, which void emerging opinion on "full death" of genetic polymorphisms as useful genetic markers. Chapters presented here demonstrate the future benefit of SNPs in many genetic studies as well as prognosis disease and diagnosis.
    Keywords: atherosclerosis, cancer, hepatocellular carcinoma, colorectal cancer, multiple sclerosis, microrna ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 4
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Green Chemistry - New Perspectives is at the frontiers of this continuously evolving interdisciplinary science, and publishes research that attempts to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The book covers all aspects of green chemistry, including chemical synthesis, nano synthesis, eco-friendly processes, biomass, extraction techniques, environmental remediation, and energy, making it a unique reference resource. This will continue to encourage scientists around the world to develop novel synthetic methods or improve the existing ones to circumvent some of the problems and favours all aspects of green chemistry. This book is intended for academia, professionals, scientists, as well as graduate and undergraduate students without any geographical limitations.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 5
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Sixty years after the "central dogma," great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specific diseases. This book is not only intended for students and researchers working in laboratory but also physicians and pharmacists. This volume consists of 14 chapters, divided into 4 parts. Each chapter is written by experts investigating biological stresses, epigenetic regulation, and functions of transcription factors in human diseases. All articles presented in this volume by excellent investigators provide new insights into the studies in transcriptional control in mammalian cells and will inspire us to develop or establish novel therapeutics against human diseases.
    Keywords: cancer, dna methylation, inflammation, breast cancer, apoptosis, aging ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 6
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: This book is a result of contributions of experts from international scientific community working in different aspects of shape memory alloys (SMAs) and reports on the state-of-the-art research and development findings on this topic through original and innovative research studies. Through its five chapters, the reader will have access to works related to ferromagnetic SMAs, while it introduces some specific applications like development of faster SMA actuators and application of nanostructural SMAs in medical devices. The book contains up-to-date publications of leading experts, and the edition is intended to furnish valuable recent information to the professionals involved in shape memory alloys analysis and applications. The text is addressed not only to researchers but also to professional engineers, students, and other experts in a variety of disciplines, both academic and industrial, seeking to gain a better understanding of what has been done in the field recently and what kind of open problems are in this area.
    Keywords: biocompatibility, phase transition, corrosion resistance, stability, specific heat ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 7
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: The book presents the fundamentals and the role of powder metallurgy in contemporary technologies and the state of the art of classical powder metallurgy technologies and a general description of new variants and special and hybrid technologies used in powder metallurgy. The next part includes over a dozen case studies provided in the following chapters, comprehensively describing authors' accomplishments of numerous teams from different countries across the world in advanced research areas relating to powder metallurgy and to special and hybrid technologies. The detailed information, largely deriving from own and original research and R&D works pursued by the authors, will be beneficial for the readers to develop their knowledge and harmonise specific information concerning these topics and will convince the manufacturers about the advantages of using the powder metallurgy technology in many branches of industry.
    Keywords: mechanical properties, additive manufacturing, sintering, carbon nanotubes, 3d printing, oxidation ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 8
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Stainless steel is an alloy steel that exhibits corrosion-resistant properties. Due to the presence of chromium (alloying element), a thin layer of chromium oxide is formed on the surface of stainless steel. The thickness of the layer is around 1–5 nm and protects the stainless steel from the atmosphere, keeping it safe from corrosion. The oxide layer is also known as the passive layer, as it will not react to any environmental conditions. The passive layer is self-repairing in nature. Any steel with 10.5% of chromium and 1.2% of carbon can be called stainless steel, of which there are five types: austenitic, ferritic, martensitic, duplex, and precipitation hardening. This book presents a literature review of studies on the different classes of stainless steel. It is a useful reference for those interested in corrosion studies of stainless steel in different corrosive solutions.
    Keywords: Industrial chemistry & manufacturing technologies ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 9
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Bismuth (Bi) is a post-transition metal element with the atomic number of 83, which belongs to the pnictogen group elements in Period 6 in the elemental periodic table. As a heavy metal, the hazard of Bi is unusually low in contrast to its neighbors Pb and Sb. This property, along with other typical characteristics like strong diamagnetism and low thermal conductivity, makes Bi attractive in industrial applications. There are more than 100 commercial bismuth products, from pharmaceutical to industrial catalysts. Based on the wide applications of Bi materials, this book goes further and mainly focuses on the potential uses of Bi-based materials, which consist of nine chapters. In addition, a special chapter concerning the defect in bismuth is also presented.
    Keywords: adsorption, photocatalysis, water treatment, dielectric properties, hydrocarbons, sol-gel ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 10
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book consists of several selected chapters on important subjects in modern high-performance liquid chromatography (HPLC) and ultra-performance liquid chromatography (UPLC). The content addresses aspects related to both improvements in the mainstream HPLC/UPLC technology and utilization, as well as developments of exploratory new materials and equipment. The book presents useful details about the presented subjects as well as describes new applications and/or relevant case studies for each subject. It is addressed to a large audience of analytical chemists involved in separation science. Each chapter is authored by scientists with considerable field and academic experience.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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  • 11
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Congenital defects in humans are of greater concern, and in that line, cystic fibrosis (CF) has been one of the most complex diseases posing treatment challenge till date. Though it is a chronic condition, CF is closely associated with dysfunction of various organ systems of the human body, which in turn results in secondary infections by microbes. Decades of research by scientists worldwide has narrowed down the cause of CF to a single target gene. But the complexity of the disease is the prime impediment to finding a single-shot cure. Fortunately, the multidisciplinary approach toward understanding and management of the CF condition has certainly increased the level of life expectancy among CF patients. In particular, the "omics" and the "systems biology" approach have greatly widened the focal area for better understanding of the disease. This book includes a collection of interesting chapters contributed by eminent scientists around the world who have been striving to improve the life of those affected by CF.
    Keywords: biofilm, pseudomonas aeruginosa, inflammation, wound healing, microbiome, insulin ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 12
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Gene expression is dependent on multiple steps, including transcription, RNA processing, and translation. Importantly, recent studies revealed that gene expression is regulated by chromatin structures and non-coding RNA profiles. Elucidating the molecular mechanisms may contribute to the development of novel therapeutics for aging-related diseases, including cancer and neurodegenerative diseases. This book provides a comprehensive overview of gene expression and its role in human disease. It consists of nine chapters organized into two sections on molecular mechanisms in controlling gene expression and the relationships between transcriptional control and human disease.
    Keywords: Pre-clinical medicine: basic sciences ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 13
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortality, cell instability, and cancer biology. We now appreciate that these unusual complexes of DNA and proteins we all know as "telomeres" are dynamic and key structures that depend on telomerase and other cellular factors for continuance. Regulation of telomere activity is a dynamic area of current research, and new insights into telomeres and their role in aging and cancer, among other biological functions and pathologies, appear regularly in the scientific world. However, one fact is more than understandable in this difficult biological conundrum: the end of the telomere story is far from being totally unraveled.
    Keywords: cancer, oxidative stress, biomarkers, chemotherapy, human health, transplantation ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 14
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Epigenetics, which deals with the study of heritable gene expression that takes place independent of changes in DNA sequence, and optogenetics, which deals with the study of genes expressed under the influence of light, are two emerging areas of study and research that have contributed immensely to our current knowledge of mechanisms and disease processes in humans. These disciplines are interrelated in the broader picture of biology and one can be used to change or modify the other. The complexity of the techniques involved in these disciplines often leads to a lack of proper understanding by researchers from other disciplines and the scientific community at large. As such, this book provides simple and easy-to-follow explanations of some of the most exciting areas of research in these disciplines.
    Keywords: Pre-clinical medicine: basic sciences ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 15
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Ongoing advances in pharmaceutical biotechnology have paved the way to ground-breaking new biological therapeutic modalities, offering the possibility of a durable curative approach for a number of life-threatening diseases, for which the medical need is as yet unmet. Over the past decades, gene therapy has seen a massive transformation from a proof-of-concept approach to a clinical reality culminating in the regulatory approval of state-of-the-art products in the European Union and in the United States. This book captures some of the scientific progresses notably in gene transfer technologies and translational development of in vivo and ex vivo gene therapy interventions in the treatment of a broad range of complex and debilitating non-inherited and inherited disorders such as: human immunodeficiency virus 1 (HIV-1) infection, cancer, cystic fibrosis, hereditary retinopathies, haemophilia B, cardiac diseases, and chronic liver fibrosis.
    Keywords: nanoparticles, heart failure, drug delivery, vaccine, hiv, cardiomyopathy ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 16
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Boron is a chemical element with three valence electrons for forming covalent bonds, resulting in many compounds. Doping/integration of boron atoms into other atoms provides new wonder materials with unique physical, chemical, and electrical properties. This book provides an overview of the research and developments of boron-based materials such as boron nitride, boron clusters, boron doping, boron compounds, and so on. Chapters cover all aspects of boron-based materials including theoretical backgrounds of structure and properties, computer simulation, synthesis techniques, device fabrication, characterizations, and current state-of-the-art applications.
    Keywords: Industrial chemistry & manufacturing technologies ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 17
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Recent Advances in Chemical Kinetics provides a comprehensive overview of several types of chemical reactions. It includes six chapters that discuss solvent catalysis, customized flow reactors, p-conjugation in kinetics, kinetics of autoxidation, molecular chameleon for cations and anions, and internal clocks of atoms.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
    Language: English
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  • 18
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: The major issue of energy saving and conservation of the environment in the world is being emphasized to us to concentrate on lightweight materials in which aluminium alloys are contributing more in applications in the twenty-first century. Aluminium and its related materials possess lighter weight, considerable strength, more corrosion resistance and ductility. Especially from the past one decade, the use of aluminium alloys is increasing in construction field, transportation industries, packaging purposes, automotive, defence, aircraft and electrical sectors. Around 85% is being used in the form of wrought products, which replace the use of cast iron. Further, the major features of aluminium alloy are recyclability and its abundant availability in the world. In general, aluminium and its related materials are being processed via casting, drawing, forging, rolling, extrusion, welding, powder metallurgy process, etc. To improve the physical and mechanical properties, scientists are doing more research and adding some second-phase particles in to it called composites in addition to heat treatment. Therefore, to explore more in this field, the present book has been aimed and focused to bridge all scientists who are working in this field. The main objective of the present book is to focus on aluminium, its alloys and its composites, which include, but are not limited to, the various processing routes and characterization techniques in both macro- and nano-levels.
    Keywords: microstructure, mechanical properties, heat treatment, aluminum, severe plastic deformation, corrosion ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 19
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Genetic diversity is the entire amount of genes and genotypes in a group of organisms and is of vital importance for their adaptation to different living conditions. If, for example, all humans were identical, the extinction of the entire kind could happen very fast. Let us care and nourish differences! The goal of this book is to present some of the contemporary thoughts on understandings of the genetic diversity patterns and their altering in a changing world. The book is aimed to the ones inspired to study and contemplate genetic diversity and to the audience beyond any frames.
    Keywords: environment, biodiversity, mutation, polymorphism, hiv-1, legislation ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 20
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Magnesium alloys usually have desirable properties including high chemical stability, easy processing and manufacturing, and also lightweight. Magnesium alloys weigh about 70% of aluminum alloy weight and 30% of iron and steel weight. Most of these alloys are used for fabrication of structures in aerospace industries. Magnesium belongs to the second main group of the periodic table of elements (alkaline earth metal) and therefore can't be found in pure state in nature and only exists as a chemical composition. This book collects new developments about magnesium alloys and their use in different industries.
    Keywords: surface treatment, electrochemistry, coating, porosity, aluminum, cardiac surgery ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 21
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Scientists and engineers for decades searched to utilize magnesium, known of its low density, for light-weighting in many industrial sectors. This book provides a broad review of recent global developments in theory and practice of modern magnesium alloys. It covers fundamental aspects of alloy strengthening, recrystallization, details of microstructure and a unique role of grain refinement. The theory is linked with elements of alloy design and specific properties, including fatigue and creep resistance. Also technologies of alloy formation and processing, such as sheet rolling, semi-solid forming, welding and joining are considered. An opportunity of creation the metal matrix composite based on magnesium matrix is described along with carbon nanotubes as an effective reinforcement. A mixture of science and technology makes this book very useful for professionals from academia and industry.
    Keywords: Pharmaceutical technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 22
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book captures in a single volume the wealth of information on the plasmid structure, function, and biology of all organisms that have been examined to date. Plasmids exhibit wide variations in size, modes of replication and transmission, host ranges, and the genes they carry and have provided us with a great understanding of basic life principles at the molecular level. Written by experts in the field, this book is a valuable source of up-to-date information, delivering the latest impacts on studies in the areas of plasmid types, genomes, purification analysis, and expression of recombinant proteins in bacteria. Plasmid utilization in the synthesis of plasmid-based vaccines, plasmids as genetic tools, and their applications in ecology and the evolutionary process are also covered. This book is a single source of valuable information for instructors and students in advanced undergraduate and graduate courses on plasmids. It will also appeal to researchers seeking to find new relationships between biological processes that are linked by plasmids to the environment.
    Keywords: immunotherapy, calcium, infectious diseases, vaccines, antigen, rna ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 23
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: Materials science is the magic that allows us to change the chemical composition and microstructure of material to regulate its corrosion-mechanical, technological, and functional properties. Five major classes of stainless steels are widely used: ferritic, austenitic, martensitic, duplex, and precipitation hardening. Austenitic stainless steels are extensively used for service down to as low as the temperature of liquid helium (-269ºC). This is largely due to the lack of a clearly defined transition from ductile to brittle fracture in impact toughness testing. Steels with ferritic or martensitic structures show a sudden change from ductile (safe) to brittle (unsafe) fracture over a small temperature difference. Even the best of these steels shows this behavior at temperatures higher than -100ºC and in many cases only just below zero. Various types of stainless steel are used across the whole temperature range from ambient to 1100ºC. This book will be useful to scientists, engineers, masters, graduate students, and students. I hope readers will enjoy this book and that it will serve to create new materials with unique properties.
    Keywords: phase transformation, mechanical properties, high temperature, x-ray diffraction, friction coefficient, selective laser melting ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 24
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: One of the first thing that comes to your mind after hearing the term “corrosion” is corrosion of a metal. Corrosion is a basically harmful phenomenon, but it can be useful in some cases. For instance, environment’s pollution with corrosion products and damage to the performance of a system are among its harmful effects, whereas electric energy generation in a battery and cathodic protection of many structures are among its advantages. However, these advantages are almost nothing as compared to the costs and effects imposed by its detrimental influences. The enormous costs of this phenomenon can be better understand through studying the published statistics on direct and indirect corrosion damages on economy of governments. The direct cost of corrosion is near 3 % of the gross domestic product (GDP) of USA. Considering this huge cost, it is necessary to develop and expand the corrosion science and its protection technologies.
    Keywords: Pharmaceutical technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 25
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This edited book, Cytogenetics - Classical and Molecular Strategies for Analysing Heredity Material, presents recent advances in the field of cytogenetics, paying special attention to methodological achievements developed worldwide that have driven the field forward. The contributors clearly discuss several concepts and approaches useful for understanding chromosomal structure and function at its various levels, highlighting chromosomes as visible carriers of heredity material.
    Keywords: chromatin, aneuploidy, chromosomes, next-generation sequencing, in vitro fertilization, acute lymphoblastic leukemia ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 26
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Genetic Diversity in Microorganisms presents chapters revealing the magnitude of genetic diversity of microorganisms living in different environmental conditions. The complexity and diversity of microbial populations is by far the highest among all living organisms. The diversity of microbial communities and their ecologic roles are being explored in soil, water, on plants and in animals, and in extreme environments such as the arctic deep-sea vents or high saline lakes. The increasing availability of PCR-based molecular markers allows the detailed analyses and evaluation of genetic diversity in microorganisms. The purpose of the book is to provide a glimpse into the dynamic process of genetic diversity of microorganisms by presenting the thoughts of scientists who are engaged in the generation of new ideas and techniques employed for the assessment of genetic diversity, often from very different perspectives. The book should prove useful to students, researchers, and experts in the area of microbial phylogeny, genetic diversity, and molecular biology.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 27
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Phylogenetics aims to study the evolutionary relatedness of living organisms in our planet. Its application is extended to the key areas such as evolution, classification and taxonomy of living organisms; ecology, diversity, and conservation biology of agrobiocenosis; monitoring of pathogen spread, outbreaks and source of transmissions, forensic analyses, etc. Historically, phylogenetics studies were prevalently based on morphological features of species that helped to classify the 'Tree of Life' on Earth. Modern phylogenetics studies, however, rely more heavily on DNA sequences. In this Phylogenetics book, we aimed to present readers the latest developments in phylogenetics studies that highlight multi-kingdom systems, reticulated evolution and conservation biology of living organisms as well as 'omics'-based phylogenetics advances.
    Keywords: bacteria, convergence, species diversity, cytogenetics, archaea ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 28
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Redox reactions are involved in biochemistry, energy, corrosion, and much more. In both biology and electrochemistry, the redox reaction is complex and varied. For example, redox shuttles in supercapacitors show aspects of molecular electrochemistry applied to electrode porosity. In pseudocapacitors, the formalism associated with their electrochemical response requires investigation and formalism. Similarly, the simple definition of redox potential opens fundamental questions about its measurement in solutions without supporting salts. This book illustrates the variety of redox reactions in its examination of the importance of redox molecules in the development of new electrical energy storage devices.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRH Electrochemistry and magnetochemistry
    Language: English
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  • 29
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and environmental contaminants, dysfunction of the oxygen transport system, malnutrition, intense exercise, and genetic variations. This book presents up-to-date knowledge about mitochondrial disease and its complex relation to some diseases such as cardiac failure, cancer, and Alzheimer's and Parkinson's diseases. This book will, therefore, be essential for readers who are interested in life sciences, especially in medicine.
    Keywords: heart failure, aging, metabolism, calcium, heart, cancer ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 30
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Skeletal muscle is a highly plastic organ that is modulated by various pathways controlling protein turnover. Muscle loss is common in muscular dystrophy, in which marked loss of various proteins such as the dystrophin-glycoprotein complex occurs around muscle fibers. This book provides a comprehensive overview of the various muscular dystrophies, including characteristics, diagnosis, and classification. General treatment of drugs (e.g. corticosteroids) and physical therapy for muscular dystrophies are discussed. In addition, current applications for cell and tissue engineering using muscle stem cells or gene therapy are introduced. This book also deals with the recent advances in appropriate models of drug screening using cell cultures or mammalian organs in vitro in this field.
    Keywords: muscular dystrophy, duchenne muscular dystrophy, quality of life, pathology, physical activity, adipogenesis ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-03-31
    Description: In the second half of the twentieth century, life expectancy was prolonged, and the number of elderly people increased. The effect of population aging increases in the frequency of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, epilepsy, and stroke. Also, a higher incidence of infections, autoimmune diseases, and malignant cancers is observed in elderly people. The aging process is difficult to define. Are physiological changes in elderly people controlled by specific genes? Is aging process a pathophysiology affecting different organs with different severity? Finding answers to these questions may help prevent age-related diseases and improve the quality of life of old people. This book was made as a compendium on contemporary challenges in senescence.
    Keywords: aging, inflammation, oxidative stress, alzheimer’s disease, apoptosis, epigenetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 32
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    Publication Date: 2024-04-05
    Description: We are living in a critical time, both for humanity and the planet, which has led us to look for more sustainable formulas to interact with the environment. One of the important changes in the design and operation of chemical processes is the search for environmentally friendly technologies. Supercritical carbon dioxide has been revealed as a promising environmentally friendly solvent that is energy efficient, selective and capable of reducing waste, making it a promising alternative to conventional organic solvents. However, reliable and versatile mathematical models of phase equilibrium thermodynamics are needed for the use of supercritical carbon dioxide in process design and viability studies. This book reviews experimental procedures for obtaining high-pressure phase equilibria data and describes the phase diagrams of binary mixtures and some thermodynamic models capable of determining the conditions of phase equilibria at high pressures. These concepts are applied to the components of the transesterification reaction of rac-2-pentanol with a vinyl ester, which is important in the pharmaceutical industry because (S)-2-pentanol can be obtained as a reaction product. This product is a key intermediate in the synthesis of drugs against Alzheimer’s disease.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
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  • 33
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    Publication Date: 2024-04-11
    Description: High-Entropy Materials - Microstructures and Properties summarizes recent developments in multicomponent materials. It discusses properties, processing, modeling, and applications of high-entropy materials, including metallic alloys and oxides. It also discusses solidification, sputtering, cryogenic treatments, CALPHAD methodology, biomedical implants, Fe-based superconductors, Fe-rich high-entropy alloys, and more.
    Keywords: Industrial chemistry & manufacturing technologies ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 34
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    Publication Date: 2024-04-11
    Description: Powder-based materials and treatment technologies rank high in contemporary scientific-technical progress due to their numerous significant technoeconomic qualities. Sintering of such materials allows saving on materials and lowering the cost price of the product, as well as manufacturing complex composite materials with unique combinations of qualities. Materials of record high values of some physic-mechanical and also biochemical characteristics can be obtained owing to structural peculiarities of super dispersed condition. Sintering of functional materials for innovative perspectives in automotive and aeronautical engineering, space technology, lightweight construction, mechanical engineering, modern design, and many other applications requires established relationship in the materials-process-properties system. Therefore, the industry being interested in understanding theoretical modeling, and control over behavior of such powdered materials has promoted the research activities of this manuscript's authors.
    Keywords: mechanical properties, composites, nanoparticle, laser, biomaterial, thermal properties ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-11
    Description: In the five sections of this peer-reviewed edited volume, the design, extraction, processing, mechanical and microstructural considerations, and applications of titanium and its alloys are examined. The design section summarizes techniques for designing materials for high-performance titanium alloys. The extraction section describes the development of extraction technologies that will produce high-purity metallic materials, using the principles of extraction metallurgy. The processing section discusses low-cost preparation technologies for titanium alloys and their applications in sustainable titanium industries. Research progress on the shock response and mechanical properties of titanium alloys, and their microstructural evolution, is dealt with in the section on mechanical properties with microstructural considerations. The final section examines the contribution of titanium applications to the development of sustainability in titanium industries.
    Keywords: Industrial chemistry & manufacturing technologies ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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  • 36
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    Publication Date: 2024-04-11
    Description: The emerging and interesting field of MOF encouraged us to bring forth the book titled ''Metal Organic Frameworks''. The book is divided into three sections. Section A consists of introduction, Section B comprises the synthesis and characterization techniques, and Section C is dedicated to the applications of MOFs. The book would be useful for scientists and researchers interested in the field of MOFs.
    Keywords: adsorption, raman spectroscopy, thermodynamics, separation, small molecules, mofs ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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  • 37
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    Publication Date: 2024-03-31
    Description: The study of DNA advanced human knowledge in a way comparable to the major theories in physics, surpassed only by discoveries such as fire or the number zero. However, it also created conceptual shortcuts, beliefs and misunderstandings that obscure the natural phenomena, hindering its better understanding. The deep conviction that no human knowledge is perfect, but only perfectible, should function as a fair safeguard against scientific dogmatism and enable open discussion. With this aim, this book will offer to its readers 30 chapters on current trends in the field of DNA replication. As several contributions in this book show, the study of DNA will continue for a while to be a leading front of scientific activities.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 38
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    Publication Date: 2024-03-31
    Description: Polymorphism or variation in DNA sequence can affect individual phenotypes such as color of skin or eyes, susceptibility to diseases, and response to drugs, vaccines, chemicals, and pathogens. Especially, the interfaces between genetics, disease susceptibility, and pharmacogenomics have recently been the subject of intense research activity. This book is a self-contained collection of valuable scholarly papers related to genetic diversity and disease susceptibility, pharmacogenomics, ongoing advances in technology, and analytic methods in this field. The book contains nine chapters that cover the three main topics of genetic polymorphism, genetic diversity, and disease susceptibility and pharmacogenomics. Hence, this book is particularly useful to academics, scientists, physicians, pharmacists, practicing researchers, and postgraduate students whose work relates to genetic polymorphisms.
    Keywords: cancer, pharmacogenetics, polymorphisms, molecular markers, drug development, pharmacokinetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-04-05
    Description: In recent decades, artificial porous structures have attracted increasing enthusiasm from researchers inspired by the fascinating molecular pores in nature and their unique biological functions. Although substantial achievements in porous materials have been realized, the construction of topologically designed pores is still challenging. Recently, the emergence of covalent organic frameworks (COFs), which are constructed based on organic and polymer chemistry, has made it possible to design artificial pores with controlled pore size, topology and interface properties. COFs are crystalline porous materials constructed by the precise reticulation of organic building blocks via dynamic covalent bonds. Distinct from non-covalent interactions which tend to produce isostructures, covalent bonds enable accurate pore design owing to their predetermined reaction pathways. In addition, the appropriate polycondensation of organic building units enables the formation of extended two-dimensional (2D) and three-dimensional (3D) polymer architectures with periodically ordered skeletons and well-defined pores. With their large surface area, tailorable structures, and tunable chemistry, COFs are regarded as potentially superior candidates for various applications including catalysis, energy storage and conversion, mass transport and biotechnology. This book examines the historic achievement of COFs, providing clear and comprehensive guidance for researchers on their structural design, synthetic protocols and functional exploration.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
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    Publication Date: 2024-04-05
    Description: Fluoride covers a continuum of topics that are frequently studied in the broad area of fluoride (F) research. It provides an overview of the primary sources of environmental fluoride in typical high-fluoride environments and demonstrates the transitions and transformations that emerge and culminate in hydro-geochemical interactions that result in fluoride-fouling of large portions of the world’s water and agricultural resources. This way, the book pinpoints the connection between F enrichment of water sources and the prevalence of endemic fluorosis in certain areas of the world. In order to contribute to a better understanding of the global fluoride problem, new fluoride detection and quantification technologies are proposed with an in-depth analysis of emerging trends in the use of portable user-friendly devices in point-of-use measurements of water fluoride. This has been presented against the backdrop of a robust overview of traditional fluoride quantification methodologies that are still in wide application among the scientific communities. In addressing fluoride toxicities, which are not limited to dental and skeletal dilapidations, the authors have explored the role of natural antioxidants in ameliorating physiological fluoride-induced noxious effects in mammalian systems. Nonetheless, since community dependence on high-fluoride water due to a lack of alternative clean water sources remains to be the principal pathway of human fluoride over-exposure, a review chapter on F mitigation techniques applied all over the world is incorporated aiming at providing a succinct overview of water defluoridation techniques and strategies being used to combat the impacts of human F overexposure around the globe. Since every cloud has a silvery lining, the possibility of using ammonium fluorides as a novel reagent in mineral processing has been considered convenient industrial fluorinating agents, which present the possibility of complete regeneration that is not afforded by the reagents presently used in decomposing silicon component of the ores.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
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    Publication Date: 2024-03-31
    Description: Matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes involved in physiological as well as in pathological processes in the human organism. MMPs play a key role in the remodeling of the extracellular matrix. Such a process may occur because of tissue homeostasis, morphogenesis, and tissue repair. However, remodeling could also be a part of many pathological states such as arthritis, cardiovascular diseases, neurodegenerative diseases, or impaired development in congenital anomalies. This book overviews the role of MMPs in different pathologies affecting the human body.
    Keywords: matrix metalloproteinases, mmps, biomarkers, heart failure, risk factors, atherosclerosis ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-04-05
    Description: This book discusses the chemistry and applications of pyridine derivatives. The library of pyridine derivatives is growing steadily with numerous synthetic analogues already described and the identification of new, naturally occurring pyridine-based compounds. The book includes ten chapters organized into two parts. The first part focuses on the numerous types of reactions that arise from pyridine derivatives. The second part examines the pharmaceutical applications of pyridine derivatives as well as their usefulness as sensors for metal cations and extracting agents for platinum group metals.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
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    Publication Date: 2024-04-05
    Description: The book discusses multiple issues associated with modern dosimetry in physics and treatment planning and how investigators from diverse world centers and institutions approach problem-solving in these important areas. It examines topics including pretreatment validation and factors affecting reference dosimetry. It also addresses unique issues affecting pediatric populations as well as the modern role of thermoluminescence validation. Several chapters discuss intensity modulation, including defining modern problems associated with both treatment planning and the definition of tumor and normal tissue contours. Furthermore, the book examines the role of imaging as both a vehicle to define tumor targets and normal tissue as well as a tool for dose validation.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRL Nuclear chemistry, photochemistry and radiation
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    Publication Date: 2024-03-31
    Description: The book Gene Duplication consists of 21 chapters divided in 3 parts: General Aspects, A Look at Some Gene Families and Examining Bundles of Genes. The importance of the study of Gene Duplication stems from the realization that the dynamic process of duplication is the “sine qua non” underlying the evolution of all living matter. Genes may be altered before or after the duplication process thereby undergoing neofunctionalization, thus creating in time new organisms which populate the Earth.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-04-11
    Description: This book contains 12 chapters with original and innovative research studies in the issues related to the broadly defined creep effect, which concerns not only the area of construction materials but also natural phenomena. The emphasis on the discussion of a new trend of experimental creep testing, which binds the classic creep methods to seek the correlation of parameters obtained in tests, deserves particular attention. This book aims to provide the readers, including, but not limited to, students and doctoral students and also the research personnel and engineers involved in the operation of equipment and structural components as well as specialists in high-temperature creep-resisting materials, with a comprehensive review of new trends in the field of creep-exposed materials and their research methodology. The chapters of this book were developed by respected and well-known researchers from different countries.
    Keywords: mechanical properties, economy, mobility, fractography, engineering design, finite element analysis (fea) ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-11
    Description: This book provides the multidisciplinary reader with a comprehensive state-of-the-art overview of research, technologies, and innovations related to iron ores. The content embraces industrial sectors and technologies dealing with mining and processing of iron ores; therefore, it covers a wide range of research fields including geoscience, deposit exploitation, resource development, comminution, beneficiation, sintering and reduction, etc. Innovations and industrial synergies across the entire production chain are broadly addressed. This book also represents advanced research methods with a focus on the genesis, mineralogy, characterization, mechanical and physicochemical properties, and environmental aspects. Interdisciplinary topics reflect cutting-edge research often reaching beyond the conventional boundaries and traditional themes.
    Keywords: sintering, biomass, ferrite, microwave radiation, scanning electron microscopy, mineralogy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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  • 47
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    Publication Date: 2024-04-05
    Description: The book comprises 14 chapters covering all the issues related to water desalination. These chapters emphasize the relationship between problems encountered with the use of feed water, the processes developed to address them, the operation of the required plants and solutions actually implemented. This compendium will assist designers, engineers and investigators to select the process and plant configuration that are most appropriate for the particular feed water to be used, for the geographic region considered, as well as for the characteristics required of the treated water produced. This survey offers a comprehensive, hierarchical and logical assessment of the entire desalination industry. It starts with the worldwide scarcity of water and energy, continues with the thermal - and membrane-based processes and, finally, presents the design and operation of large and small desalination plants. As such, it covers all the scientific, technological and economical aspects of this critical industry, not disregarding its environmental and social points of view. One of InTech's books has received widespread praise across a number of key publications. Desalination, Trends and Technologies (Ed. Schorr, M. 2011) has been reviewed in Corrosion Engineering, Science & Technology – the official magazine for the Institute of Materials, Minerals & Mining, and Taylor & Francis's Desalination Publications. Praised for its “multi-faceted content [which] contributes to enrich it,” and described as “an essential companion...[that] enables the reader to gain a deeper understanding of the desalination industry,” this book is testament to the quality improvements we have been striving towards over the last twelve months.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
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    Publication Date: 2024-03-31
    Description: This book offers a collection of chapters addressing different studies on DNA repair from a cellular and molecular point of view. The various contributions highlight the vastness of DNA repair process and the need for a deeper understanding. To this end, the recent considerations here presented can be a cue for scientists and students working on, or interested in, the subject of DNA repair in human cells. This book may suggest to readers new avenues of interplay between different kinds of DNA damage and cellular response for maintaining nuclear and mitochondrial genomic stability.
    Keywords: dna damage, mmr, oxidative stress, mitochondria, epigenetics, angiogenesis ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-03-31
    Description: This book covers the dynamic process of genetic diversity in living organisms. It comprises eight chapters that address various topics, including genetic diversity in crop production, the relationship between viruses and their hosts, patterns of genetic variability in silver carp populations in Pakistan, molecular markers used for wildlife conservation, and more.
    Keywords: mitochondria ; evolution ; molecular markers ; quorum sensing ; microorganism ; bacteriophages ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-04-11
    Description: Shape-memory materials are materials that react under variations of electric or magnetic fields, physical or chemical changes, and that when returning to the initial conditions recover their original form, capable of repeating this process an infinite number of times without deteriorating. The characteristics, fabrication techniques, and thermomechanical treatment of various shape-memory materials are described in detail in this book. The book describes several principles and applications.
    Keywords: simulation, finite element analysis, hydrogels, smart materials, self-healing, phase transformation ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-03-31
    Description: Genetic transformation of plants has revolutionized both basic and applied plant research. Plant molecular biology and physiology benefit from this power fool, as well as biotechnology. This book is a review of some of the most significant achievements that plant transformation has brought to the fields of Agrobacterium biology, crop improvement and, flower, fruit and tree amelioration. Also, it examines their impact on molecular farming, phytoremediation and RNAi tools.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-03-31
    Description: "Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells.
    Keywords: cancer, inflammation, breast cancer, melanoma, immunity, micrornas ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-04-11
    Description: A resistance of magnesium alloys to surface degradation is paramount for their applications in automotive, aerospace, consumer electronics and general-purpose markets. An emphasis of this book is on oxidation, corrosion and surface modifications, designed to enhance the alloy surface stability. It covers a nature of oxides grown at elevated temperatures and oxidation characteristics of selected alloys along with elements of general and electrochemical corrosion. Medical applications are considered that explore bio-compatibility of magnesium alloys. Also techniques of surface modifications, designed to improve not only corrosion resistance but also corrosion fatigue, wear and other behaviors, are described. The book represents a valuable resource for scientists and engineers from academia and industry.
    Keywords: Pharmaceutical technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-03-31
    Description: Because genetic factors can impact immune responses, and immunogenetic associations serve as a predictor of disease development and as a biological indicator of disease progression, the study of immunogenetics is important to basic genetics and immunology, as well as to translational and individualized medicine.This book addresses a few but important issues on the subject of immunogenetics. First, it will review the role that human leukocyte antigen molecules play in the immune system and then take into consideration the effectiveness of Western blotting for the detection of immunologic proteins. The book will discuss studies on the immunogenetics of cancer and tuberculosis followed by implications for immunotherapy. Working separately, the book will also provide evidence that the application of immunogenetics has improved our understanding of brain and behavior disorders.
    Keywords: autoimmune diseases, elisa, immune modulation, immunoassay, adjuvants ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-04-11
    Description: Major casting processing advancements have been made in experimental and simulation areas. Newly developed advanced casting technologies allow foundry researchers to explore detailed phenomena associated with new casting process parameters helping to produce defect-free castings with good quality. Moreover, increased computational power allows foundry technologists to simulate advanced casting processes to reduce casting defects. In view of rapid expansion of knowledge and capability in the exciting field of casting technology, it is possible to develop new casting techniques. This book is intended to discuss many casting processing technologies. It is devoted to advanced casting processing technologies like ductile casting production and thermal analysis, casting of metal matrix composites by vortex stir casting technique, aluminum DC casting, evaporative casting process, and so on. This book entitled Advanced Casting Technologies has been organized into seven chapters and categorized into four sections. Section 1 discusses the production of ductile iron casting and thermal analysis. Section 2 depicts aluminum casting. Section 3 describes the casting manufacturing aspects of functionally graded materials and evaporative casting process. Section 4 explains about the vortex stir casting technique to process metal matrix composite castings. All the chapters discussed in detail the processing steps, process parameters involved in the individual casting technique, and also its applications. The goal of the book is to provide details on the recent casting technologies.
    Keywords: solidification, stir casting, optimization, microstructure, mechanical properties, aluminum ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-05
    Description: Progress in agricultural, biomedical and industrial applications' is a compilation of recent advances and developments in gas chromatography and its applications. The chapters cover various aspects of applications ranging from basic biological, biomedical applications to industrial applications. Book chapters analyze new developments in chromatographic columns, microextraction techniques, derivatisation techniques and pyrolysis techniques. The book also includes several aspects of basic chromatography techniques and is suitable for both young and advanced chromatographers. It includes some new developments in chromatography such as multidimensional chromatography, inverse chromatography and some discussions on two-dimensional chromatography. The topics covered include analysis of volatiles, toxicants, indoor air, petroleum hydrocarbons, organometallic compounds and natural products. The chapters were written by experts from various fields and clearly assisted by simple diagrams and tables. This book is highly recommended for chemists as well as non-chemists working in gas chromatography.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
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    Publication Date: 2024-04-11
    Description: Metallic glasses are very promising engineering and functional materials due to their unique mechanical, chemical, and physical properties, attracting increasing attention from both scientific and industrial communities. However, their practical applications are greatly hindered due to three main problems: dimensional limit, poor tension plasticity, and difficulty in machining and shaping. Therefore, further investigation of these issues is urgently required. This book provides readers with recent achievements and developments in the properties and processing of metallic glasses, including mainly thermoplastic forming of metallic glasses (Chapter 2), atomic-level simulation of mechanical deformation of metallic glasses (Chapter 3), metallic glass matrix composites (Chapter 4), and tribo-electrochemical applications of metallic glasses (Chapters 5 and 6).
    Keywords: tribocorrosion, friction, plasticity, molecular dynamics simulation, mechanical property, mechanical behavior ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-05
    Description: This book discusses electrocatalysis and electrocatalysts for energy, water electrolysis, water treatment, CO2 conversion, and green chemistry. It reviews various electrocatalysts and their properties and electrochemical performances. The first section of the book covers topics in direct alcohol fuel cells including Pt-based electrocatalysts as non-carbon electrode support materials and the development of electrocatalysts for direct methanol fuel cells. The second section of the book covers various topics in electrocatalysis and electrocatalysts for a cleaner environment, including electrocatalysts for the conversion of CO2 to valuable products and SYNGAS, electrocatalysts for water electrolysis, and much more.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRH Electrochemistry and magnetochemistry
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book focuses on the transcriptional and post-transcriptional gene regulations and presents a detailed portrait of many novel aspects related to highlighting the importance of key TFs in some vital biological processes, the role of certain TFs to control some infectious diseases, the role of non-coding RNAs in controlling mRNA expression, the involvement of these non-coding RNAs in diseases, and the interplay between TFs and microRNAs as key players for gene expression regulation giving a complete picture of how genes are regulated at the cellular level. The editor embarked upon this writing project entitled "Transcriptional and Post-transcriptional Regulation" to make pertinent contributions accessible to the scientific community. Hopefully, a large audience will enjoy reading and benefit from the chapters of this book.
    Keywords: dna methylation, cancer, gene expression, micrornas, epigenetic, mirnas ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-03-31
    Description: Cytogenetics - Past, Present, and Further Perspectives discusses events that influenced the development of cytogenetics as a specialty within biology, with special attention paid to methodological achievements developed worldwide that have driven the field forward. Improvements to the resolution of chromosome analysis followed closely the introduction of innovative analytical technologies. In that sense, this book reviews and provides a brief account of the structure of chromosomes and stresses the high structural conservation in different species with an emphasis on aspects that require further research. However, it should be kept in mind that the future of cytogenetics will likely depend on improved knowledge of chromosome structure and function.
    Keywords: chromosome, evolution, wheat, hybridization, mammals, karyotype ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-03-31
    Description: Mutations in the BRCA1/2 genes are the most common cause of hereditary breast and ovarian cancer (HBOC), and HBOC is an autosomal dominant cancer predisposition syndrome. Individuals with HBOC have a high risk for breast and ovarian cancers and a moderate risk for other cancers, such as prostate, pancreatic, melanoma, and fallopian tube cancers. The goal of screening individuals at high risk of familial cancer is either prevention (such as a change in lifestyle or diet) or early detection of cancer. The identification of BRCA mutation carriers is important, since increased surveillance, drug therapy, and prophylactic surgery can reduce cancer-related morbidity and mortality. In recent years, there has been substantial development in BRCA-associated hereditary breast and/or breast-ovarian cancer research and its clinical applications. In this context, this book consolidates the recent advances in BRCA-related cancer biology and therapeutics, covering a wide spectrum of interrelated topics. Chapters cover a wide range of topics, such as BRCA discovery, BRCA structure and function, BRCA-associated cancers, BRCA genetic testing and counselling, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.
    Keywords: Pre-clinical medicine: basic sciences ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-04-11
    Description: This book explores synthesis, structural changes, properties, and potential applications of transition metal (TM) compounds. Over three sections, chapters cover such topics as the synthesis of pentoxide vanadium (V2O5), the effect of TM compounds on structural, dielectric properties and high-temperature superconductors, and TM-doped nanocrystals (NCs).
    Keywords: biocompatibility, x-ray diffraction, dielectric properties, nanocrystals, ferrite, photovoltaics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-11
    Description: High-entropy alloys (HEAs) are a new class of materials attracting attention from researchers all over the world. This book provides a comprehensive overview of the research on HEAs, as well as discusses the mechanical, physical, and chemical properties of new HEAs and their potential applications. Chapters cover such topics as HEA superconductors, HEA composites, high-entropy superalloys, artificial intelligence in HEA design, and more.
    Keywords: mechanical properties, artificial intelligence, aluminum alloys, fesem, superconductivity, high entropy alloys ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-11
    Description: This book discusses liquid metals used in various manufacturing processes in the aerospace and automobile industries. It provides important original and theoretical experimental results on the use of non-routine technologies. It also presents novel applications of more familiar experimental techniques and analyses of composites. Topics covered include the importance of liquid metals, friction stir welding to improve aluminium alloys, adhesion phenomenon of liquid metals, secondary aluminium used for producing products, and more.
    Keywords: microstructure, corrosion, wear, ceramics, additives, adhesion ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-05
    Description: Surfactants are ubiquitous and have applications in diverse areas, including food, cosmetics, detergents, lubricants, enhanced oil recovery (EOR), and targeted drug delivery systems. Their wide diversity of applications owes to their unique structure, namely, a hydrophilic and a hydrophobic group present in the same molecule. Although most surfactants used industrially are synthetic, there is a growing need for natural surfactants, as the latter is obtainable from renewable sources and are less toxic and highly biodegradable in contrast to their synthetic counterparts. This book is a compilation of interesting articles by various experts that cover various applications of both synthetic and natural surfactants.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRC Colloid chemistry
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    Publication Date: 2024-03-31
    Description: RNA interference (RNAi) is a widely used technology for gene silencing and has become a key tool in a myriad of research and lead discoveries. In recent years, the mechanism of RNAi agents has been well investigated, and the technique has been optimized for better effectiveness and safety. On the other hand, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9/gRNA system is a recent, novel, targeted genome-editing technique derived from the bacterial immune system. Recent advances in gene-editing research and technologies have enabled the CRISPR Cas9 system to become a popular tool for sequence-specific gene editing to correct and modify eukaryotic systems. In this book, we will focus on the mechanisms, applications, regulations (their pros and cons), and various ways in which RNAi-based methods and CRIPSR-Cas9 technology have stimulated the modulation of gene expression, thereby making them a promising therapeutic tool to treat and prevent complex diseases and disorders.
    Keywords: machine learning, breast cancer, gene therapy, clinical trials, nanoparticle, crispr/cas9 ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-04-05
    Description: The chemical sensor plays an essential role in the fields of environmental conservation and monitoring, disaster and disease prevention, and industrial analysis. A typical chemical sensor is a device that transforms chemical information in a selective and reversible way, ranging from the concentration of a specific sample component to total composition analysis, into an analytically useful signal. Much research work has been performed to achieve a chemical sensor with such excellent qualities as quick response, low cost, small size, superior sensitivity, good reversibility and selectivity, and excellent detection limit. This book introduces the latest advances on chemical sensors. It consists of 15 chapters composed by the researchers active in the field of chemical sensors, and is divided into 5 sections according to the classification following the principles of signal transducer. This collection of up-to-date information and the latest research progress on chemical sensor will provide valuable references and learning materials for all those working in the field of chemical sensors.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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    Publication Date: 2024-04-05
    Description: Distillation is an important separation technique that has been used for many centuries to exploit the volatility differences between components in a mixture. The distillation process has many variations and applications. This book includes two sections on desalination and reactive distillation. It discusses desalination in the processes of solar and membrane distillation, with a focus on the reduction of energy costs to obtain potable water. It also discusses reactive distillation, which can be used in some cases to reduce the power duty in the separation process by using the reaction heat directly in the separation. The book includes cases of mathematical modeling, simulation, and optimization of the distillation process.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
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    Publication Date: 2024-04-11
    Description: Gold and noble metals have been attractive to humans from ancient times because of their beautiful features. In modern society, noble metals, especially gold, play important roles as components in electronic devices because of their high electrical conductivity, chemical stability, and density. In the field of MEMS devices, the demand for continuous miniaturization and sensitivity enhancement is always high. Especially for MEMS accelerometers, sensitivity is affected by Brownian noise, and components with sufficient mass are needed to suppress this noise. Therefore, it is difficult to reduce the dimensions of components to allow further miniaturization of the device. This book presents recent progress in noble metal electrodeposition and applications of gold-based materials in the realization of highly sensitive CMOS-MEMS accelerometers.
    Keywords: microstructure, tio2, carbon dioxide, nanostructure, anisotropy, electrolyte ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-03-31
    Description: This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-04-11
    Description: Post-Transition Metals compiles information on synthesis, properties, characterization, and potential applications of post-transition metals such as indium and gallium. These metals are important for their optical, structural, morphological, and electronic properties. This book provides an overview of the history as well as the physical, structural, optical, and chemical properties of post-transition elements. It also discusses methods for the detection and separation of these metals, including special methods for determining their presence in industrial and organometallic products. The information contained herein is useful for physicists, researchers, chemists, materials engineers, and students.
    Keywords: gaas, optical properties, solar cells, physical properties, noise, photonics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-03-31
    Description: This edited book, Chromosomal Abnormalities - A Hallmark Manifestation of Genomic Instability, contains a series of chapters highlighting several aspects related to the generation of chromosomal abnormalities in genetic material. We are extremely grateful to the authors who had contributed with valuable information about the role of genomic instability in pathological disorders as well as in the evolution process.
    Keywords: cancer, alzheimer’s disease, neurodegeneration, pathology, hybridization, drosophila ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-04-11
    Description: Strontium aluminate cement is special inorganic cement with the properties which make it favorable for various special applications such as refractory products, macro defect free (MDF) composites, blended cements and expansive cements for high temperature applications. There is an immense number of possible combinations which can be made to prepare blended and multicomponent cements and to investigate the influence of substitutions on the properties of strontium aluminate. Divided into ten sections, this book provides the latest research achievements in many aspects of this binder. The manufacturing, the hydration process, the setting behavior and the properties are described. The book contains many original and firstly published experimental research results obtained during writing. Currently there is no comprehensive work on this topic in literature. From this point of view, the book is a pilot work on this topic and should attract the attention of researchers and bring further progress of this topic.
    Keywords: Pharmaceutical technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-03-31
    Description: Microsatellite or so-called simple sequence repeat (SSR) markers have been one of the most reliable molecular markers derived from the DNA molecule, which were widely and successfully used for more than 25 years in the genetic studies of environmental, agricultural, and biomedical sciences. The objective of this Microsatellite Markers book is to rehighlight and provide some updates on previous and recent utilization of microsatellite markers for various applications in agriculture and medicine, which void emerging opinion on "full death" of microsatellites as useful genetic markers. Chapters presented here demonstrate the future benefit of SSRs in many genetic studies as well as disease diagnosis and prognosis.
    Keywords: microsatellites, cancer, colorectal cancer, maize, livestock, genetic diversity ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-04-11
    Description: The use of copper, silver, gold and platinum in jewelry as a measure of wealth is well known. This book contains 19 chapters written by international authors on other uses and applications of noble and precious metals (copper, silver, gold, platinum, palladium, iridium, osmium, rhodium, ruthenium, and rhenium). The topics covered include surface-enhanced Raman scattering, quantum dots, synthesis and properties of nanostructures, and its applications in the diverse fields such as high-tech engineering, nanotechnology, catalysis, and biomedical applications. The basis for these applications is their high-free electron concentrations combined with high-temperature stability and corrosion resistance and methods developed for synthesizing nanostructures. Recent developments in all these areas with up-to-date references are emphasized.
    Keywords: cancer, nanoparticles, density functional theory, gold nanoparticles, silver, plasmonics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-11
    Description: Current Trends in Magnesium (Mg) Research discusses recent research activities in which magnesium plays a central role, in its several forms as composites, alloys, or compounds. Mg alloys/composites/compounds are widely used in the transportation industry (both air and ground) and medical industry (bone/dental implants) and are being tested for use in the energy sector as alternatives to Li-ion batteries. Chapters address such topics as the role of Mg in diverse fields, the environmental impact of Mg processing technologies, Mg as a biomaterial in aiding the growth of bone tissues, corrosion protection of Mg alloys, the wear behavior of Mg hybrid composites, and synthesis of Mg compounds for practical applications in industry.
    Keywords: Industrial chemistry & manufacturing technologies ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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    Publication Date: 2024-03-31
    Description: Restricted growth conditions are a group of genetic disorders with primary effect on growth (short stature); it is very heterogeneous and comprises two important categories: skeletal dysplasia and different genetic syndromes with primary effect on growth. It could also be caused by a medical condition. The book contains chapters regarding different aspects of the study of restricted growth that are divided into three broad sections. Section I: Defining Restricted Growth, Section II: Genetics and Diagnosis of Restricted Growth, and Section III: Signaling Pathways and Molecular Mechanisms of Restricted Growth. The book presents comprehensive reviews of each topic written by experts in the field. It will be the most valuable tool for physicians and life science researchers and students. We hope that the book will motivate discussion and research in this important health problem, setting the path for better therapeutic approaches.
    Keywords: growth hormone, metabolism, cartilage, tumor suppressor, genetic testing, chondrocyte ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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    Publication Date: 2024-04-11
    Description: Aluminium alloys are among the most interesting materials being adopted for weight reduction and recycling benefits. The increasing importance of aluminium alloys over the years is due to their widespread use and applications in automotive, aerospace, food handling, building, heat exchange, and electrical transmission industries. Their high strength/weight ratio makes aluminium alloys useful for applications where simultaneous high strength and lightness are needed.This book provides a comprehensive review of the design and development of innovative aluminium alloys and composites. Chapters discuss manufacturing processes and applications and are heavily illustrated to make the concepts clear.
    Keywords: Industrial chemistry & manufacturing technologies ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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    Publication Date: 2024-03-31
    Description: Population genetics is a theoretical field of biology that studies allelic and genetic frequencies in living organisms, thus allowing us to infer what evolutionary processes are acting on individuals over generations and predict the adaptive consequences of these changes in the gene pool. Knowing the structure and genetic diversity of populations is essential for a proper understanding of the evolution, speciation processes, and dynamics of living beings. This knowledge is extremely useful for some practical applications, such as species management and conservation strategies, vector and pathogen monitoring and control, plant and animal breeding, and genetic improvement. This book includes carefully selected works in population genetics reviewed by geneticists.
    Keywords: Pre-clinical medicine: basic sciences ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-04-11
    Description: Classical magnesium alloys are a combination of aluminium, magnesium, manganese and zinc. Magnesium combined with lithium forms ultralight alloys that have many uses. Since it is a reasonable material, it offers great possibilities and is constantly tested at various angles of applications and properties. Magnesium, previously used for military purposes, seems to fit perfectly to the requirements of the currently prevailing technology. Low density with appropriate mechanical properties (strength, high operating temperature), good foundry properties (high castability and low shrinkage), vibration damping ability and cost-effectiveness of recycling seem to be an ideal response to market needs. All things considered, magnesium alloys are the perfect material used in various industries starting from the automotive industry, through sport, electronics up to the space industry and defence. This book is written by experts in various areas of magnesium science and technology. It gives a general idea of modern advancements in theory and practical purposes of magnesium alloys. The book reports fundamental aspects of corrosion types and details about magnesium alloys designed to work in elevated temperatures and superplastic behaviour. Fundamentals, broad experience, theory as well as complex technological aspects make this work helpful for engineers and scientists from all over the world.
    Keywords: microstructure, corrosion, mechanical properties, biomaterials, hydrogen, polarization ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-11
    Description: Titanium dioxide is currently being used in many industrial products. It provides unique photocatalytic properties for water splitting and purification, bacterial inactivation, and organics degradation. It has also been widely used as the photoanode for dye-sensitized solar cells and coatings for self-cleaning surfaces, biomedical implants, and nanomedicine. This book covers various aspects of titanium dioxide nanomaterials including their unique one-dimensional, two-dimensional, mesoporous, and hierarchical nanostructures and their synthetic methods such as sol-gel, hydrothermal, anodic oxidation, and electrophoretic deposition, as well as its key applications in environmental and energy sectors. Through these 24 chapters written by experts from the international scientific community, readers will have access to a comprehensive overview of the recent research and development findings on the titanium dioxide nanomaterials.
    Keywords: nanoparticles, composites, tio2, water treatment, solar cells, surface treatment ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-04-11
    Description: Metamaterials have become one of the most important emerging technologies in the scientific community due to its unusual electromagnetic properties. Consequently, during the last years, a huge deal of efforts has been concentrated in order to design functional components and devices based on metamaterials for many potential applications. The main objective of this book is to present in-depth analysis of the theory, properties, and realizations of novel devices that could be integrated within modern and future communication systems. The book contains 11 chapters written by acknowledged experts, researchers, academics, and microwave engineers, providing comprehensive information and covering a wide range of topics on several aspects of microwaves and optics, including polarization conversion, asymmetric transmission, transmission lines, filters, plasmonic lenses, tunable metamaterials, light manipulation, absorbers, and antennas, among others. This book is suitable for scholars from large scientific domain and therefore given to engineers, scientists, graduates, and other interested professionals as a reference on these artificial materials of tomorrow.
    Keywords: fractal, ferrite, antennas, metasurfaces, orbital angular momentum, ultra-wideband ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    Publication Date: 2024-03-31
    Description: DNA is the most important biomolecule ever discovered. Indeed, this molecule bears genetic information from one generation to another. In this regard, DNA bases have a key role in transferring genetic information and data safely. However, there are cellular, genetic, and environmental factors that may damage the different parts of DNA molecules. These damages may result in mutations and cell death. As such, several DNA repair mechanisms have evolved. Over three sections, this book examines many of these mechanisms.
    Keywords: cancer, dna repair, dna damage, genome instability, drug resistance, neurodegenerative diseases ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-03-31
    Description: The discovery of noncoding RNAs (ncRNAs) is changed our understanding of genome, transcriptome, and interactions with proteome in a cell. Since the discovery of the first microRNA (miRNA) called lin-4 on Caenorhabditis elegans in 1993, our understanding of gene expression has deepened. Further miRNA discoveries have led to the investigation of new ncRNA families and their function, biogenesis, and interactions with other types of molecules. Recent developments in bioinformatics, public databases, sequencing technologies, and biochemical techniques have increased our understanding of the biogenesis, function, and interactions of ncRNAs. This book provides an overview of current ncRNA research dealing with human diseases and cancer and plant miRNAs.
    Keywords: Pre-clinical medicine: basic sciences ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-04-05
    Description: Cyclodextrins (CDs) have attracted great interest from the research community as well as industries in an array of sectors because of their unique structural features. This book provides a comprehensive overview of CDs, beginning with their historical background. Chapters address such topics as the structure and physiochemical properties of CDs, advancements in the field, and potential applications of these materials in fields such as drug delivery and sensing. This book reveals new frontiers in the CD world and is a useful resource for organic, analytical, and supramolecular chemists as well as scientists engaged in biological and material sciences.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
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    Publication Date: 2024-04-05
    Description: The book presents a comprehensive overview of sorption, which is a multi-parametric separation process. It is extensively used in the removal of various pollutants from the tertiary stage of wastewater treatment, from leachates, etc. It discusses fundamental points of the technique as well as kinetic theories and isotherms. It also examines the synthesis and characterizations of all studied adsorbent materials to find their paths of sorption. Finally, it highlights the importance of having a cost-estimation plan for the synthesis of sorbent materials as well as predictions for their reusability.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRX Surface chemistry and adsorption
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    Publication Date: 2024-03-31
    Description: Genetic diversity is one of the measures of biodiversity and has consequences in biological variation. It is crucial to understand the evolutionary and adaptative processes in all living species. This book is an interdisciplinary and integrated work that will contribute to the knowledge of academics from different areas of biological sciences. This collection of scientific papers was chosen and analyzed to offer readers a broad and integrated view of the importance of genetic diversity in the evolution and adaptation of living beings, as well as practical applications of the information needed to analyze this diversity in different organisms. This book was edited by geneticist researchers and provides academics with up-to-date and quality information on the subject.
    Keywords: molecular markers, covid-19, genetics, food security, sars-cov-2, malaria ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
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    Publication Date: 2024-04-11
    Description: Rare Earth Elements - Emerging Advances, Technology Utilization, and Resource Procurement illustrates the global interest in rare earth elements. The section on “Emerging Advances and Technology” presents research on the usage of rare earth elements in emerging technologies involving medicine, digital technology, mineral processing, and chemistry. The section on “Utilization and Resource Procurement” focuses on the global issues of pollution because of rare earth mining. The research presented underlies the rapid development of emerging technologies that require rare earth elements and the social issues that arise because of these technologies.
    Keywords: sensors ; luminescence ; lanthanides ; molecular dynamics ; leaching ; environmental impact ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: The very short genomes of mitochondria summarize the complexity of molecular biology and its interactions with cellular and whole organism biology. Studies of mitogenomes contribute to the understanding of molecular biology and evolution, and to health management. Despite or even due to their small sizes, mitogenomes continue to surprise us. Studies of mitogenomes reveal the details of molecular organization and its evolution under constraints for miniaturization.
    Keywords: oxidative stress, cancer, aging, cancer therapy, nervous system, hydrogen bond ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 90
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book edition is intended to provide a concise summary for select topics in DNA repair, a field that is ever-expanding in complexity and biologic significance. The topics reviewed ranged from fundamental mechanisms of DNA repair to the interface between DNA repair and a spectrum on cellular process to the clinical relevance of DNA repair in oncologic paradigms. The information in this text should provide a foundation from which one can explore the various topics in depth. The book serve as a supplementary text in seminar courses with focus on DNA repair as well as a general reference for scholars with an interest in DNA repair.
    Keywords: Medical genetics ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 91
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book provides a concise yet comprehensive source of current information on Down syndrome. It focuses on exciting areas of research on chromosome editing, neurogenomics and diseases associated with Down syndrome. Research workers, scientists, medical graduates and physicians will find this book as an excellent source for consultation and references. Key features of this book are chromosome engineering in Down syndrome, mental retardation and cognitive disability, prenatal diagnosis and diseases associated with Down syndrome. Although aimed primarily for research workers on Down syndrome, we hope that the appeal of this book will extend beyond the narrow confines of academic interest and be exciting to wider audience, especially parents, relatives and health care providers who work with infants and children with Down syndrome.
    Keywords: data mining, ultrasound, mental health, screening, crispr/cas9, congenital heart disease ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 92
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: The large potential of RNA sequencing and other "omics" techniques has contributed to the production of a huge amount of data pursuing to answer many different questions that surround the science's great unknowns. This book presents an overview about powerful and cost-efficient methods for a comprehensive analysis of RNA-Seq data, introducing and revising advanced concepts in data analysis using the most current algorithms. A holistic view about the entire context where transcriptome is inserted is also discussed here encompassing biological areas with remarkable technological advances in the study of systems biology, from microorganisms to precision medicine.
    Keywords: gene expression, transcriptome, epigenetics, genomics, proteomics, microrna ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 93
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Antibody Engineering comprises in vitro selection and modification of human antibodies including humanization of mouse antibodies for therapy, diagnosis, and research. This book comprises an overview about the generation of antibody diversity and essential techniques in antibody engineering: construction of immune, naive and synthetic libraries, all available in vitro display methods, humanization by chain shuffling, affinity maturation techniques, de novo synthesis of antibody genes, colony assays for library screening, construction of scFvs from hybridomas, and purification of monoclonal antibodies by exclusion chromatography. In addition, other topics that are discussed in this book are application and mechanism of single domain antibodies, structural diversity of antibodies, immune-mediated skin reactions induced by TNF-alpha recombinant antibodies, and bioinformatic approaches to select pathogen-derived peptide sequences for antibody targets.
    Keywords: phage display, bioinformatics, screening, infectious diseases, e. coli, pseudomonas aeruginosa ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 94
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book examines the fundamentals of molecular cloning and molecular cloning applications in various areas. Chapters address such topics as tools and methodologies of molecular cloning, molecular cloning for medicine, food and feed, the environment, and the future of molecular cloning.
    Keywords: gene therapy, clinical trials, dna, genome editing, microfluidic, crispr/cas ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 95
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Carotenoids are natural and versatile secondary metabolites, most of them showing colours that vary from yellow to red. They are widespread among living beings where they are involved in many biological roles reporting beneficial actions. To date, more than 750 carotenoids have been described in nature. Humans cannot synthesize carotenoids de novo, thus they are mainly obtained through diet. In fact, carotenoids are consistently found in tissues or biological fluids where they play a beneficial decreasing the risk of developing some diseases.During the last half-century, significant advances in carotenoids research have been made. This book highlights new perspectives and applications of carotenoids including characterization and isolation of new compounds (including rare carotenoids), their production at a mid-large scale (involving new innovative approaches), and uses of carotenoids in different biotechnological fields like food science, biomedicine, and cosmetics.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 96
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Infrared Spectroscopy - Perspectives and Applications is a compendium of contributions from experts in the field of infrared (IR) spectroscopy. This assembly of investigations and reviews provides a comprehensive overview of the fundamentals as well as the groundbreaking applications in the field. Chapters discuss IR spectroscopy applications in the food and biomedicine sectors and for measuring transport through polymer membranes, characterizing lignocellulosic biomasses, detecting adulterants, and characterizing enamel surface advancements. This book is an invaluable resource and reference for students, researchers, and other interested readers.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry::PNFS Spectrum analysis, spectrochemistry, mass spectrometry
    Language: English
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  • 97
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: In general, metallic alloys are the interdisciplinary subject or even an area that cover physics, chemistry, material science, metallurgy, crystallography, etc. This book is devoted to the metallic alloys. The primary goal is to provide coverage of advanced topics and trends of R&D of metallic alloys. The chapters of this book are contributed by the respected and well-known researchers which have presented results of their up-to-date metallic alloys technologies. The book consists of two blocks filled with 10 chapters which provide the results of scientific studies in many aspects of the metallic alloys including the studies of amorphous and nanoalloys, modeling of disordered metallic alloys, superconducting alloys, differential speed rolling of alloys, meta-magnetic Heusler alloys, etc. The book is of interest to both fundamental research and practicing scientists and will prove invaluable to all chemical and metallurgical engineers in process industries, as well as to students and engineers in industry and laboratories. We hope that readers will find this book interesting and helpful for the work and studies. If so, this could be the best pleasure and reward for us.
    Keywords: wear, thermal stability, extrusion, metallic glasses, phase transformation, cast iron ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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  • 98
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: p53 is a protein that plays an important role in the regulation of cell division and thereby offers protection to the cell against malignant transformation. This is the most well-studied and most appreciated role of p53, due to which the protein is famously known as the “guardian of the genome.” It is the most studied protein in all forms of cancer research, with much of this research investigating p53’s role in tumor suppression. However, research has also shown that p53 plays a role in a wide range of other cellular functions, like serving as a biomarker for environmental pollution. Even as a tumor suppressor and transcription factor, many aspects of p53 function are still obscure, and research in the field is continually attempting to shed light on these functions. This book examines and discusses the myriad roles of p53 and different aspects of its functions. Chapters examine p53 in cancer prevention, DNA repair, gene regulation, and more.
    Keywords: Pre-clinical medicine: basic sciences ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 99
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Oligonucleotide-based diagnostics and therapeutics are attracting attention from the scientific community. In recent years, the range of applications for oligonucleotides has broadened in innovative and creative directions, such as disease diagnostics, cancer prognosis and more. It played an important role during the COVID pandemic in rapid PCR testing as well as modified mRNA-based life-saving vaccines. Various modifications of natural nucleotide bases have been evaluated for several theranostic applications. The development of nucleotide and oligonucleotide therapeutics has been growing in importance over the past few decades. This book examines new developments in oligonucleotide-based research and provides a comprehensive overview of the state of the art in this exciting discipline.
    Keywords: machine learning ; microrna ; dna damage ; protein ; phagocytosis ; random forest ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 100
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-11
    Description: There are only a few discoveries and new technologies in materials science that have the potential to dramatically alter and revolutionize our material world. Discovery of two-dimensional (2D) materials, the thinnest form of materials to ever occur in nature, is one of them. After isolation of graphene from graphite in 2004, a whole other class of atomically thin materials, dominated by surface effects and showing completely unexpected and extraordinary properties, has been created. This book provides a comprehensive view and state-of-the-art knowledge about 2D materials such as graphene, hexagonal boron nitride (h-BN), transition metal dichalcogenides (TMD) and so on. It consists of 11 chapters contributed by a team of experts in this exciting field and provides latest synthesis techniques of 2D materials, characterization and their potential applications in energy conservation, electronics, optoelectronics and biotechnology.
    Keywords: graphene, thermal conductivity, 2d materials, mechanical properties, graphene oxide, thin films ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDP Other manufacturing technologies::TDPM Metals technology / metallurgy
    Language: English
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