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  • bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine  (36)
  • thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology  (32)
  • Chemistry
  • Life and Medical Sciences
  • IntechOpen  (89)
  • 2020-2024  (89)
  • 1950-1954
  • 1945-1949
  • 2023  (89)
Collection
Keywords
Publisher
Language
Years
  • 2020-2024  (89)
  • 1950-1954
  • 1945-1949
Year
  • 1
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    Novel Pathogenesis and Treatments for Cardiovascular Disease (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-09-05
    Description: This book provides a comprehensive overview of cardiovascular diseases (CVDs) and associated conditions. It is organized into three sections on “Cardiovascular Pathophysiology”, “Cardiovascular Diagnostics”, and “Cardiovascular Treatments”. Chapters address such topics as the role of obesity in CVD, cardiotoxicity, cardio-oncology, CVD in different disease states, modalities for detecting CVD, interventional strategies to prevent or treat CVD, and much more.
    Keywords: cancer ; covid-19 ; obesity ; diabetes ; hypertension ; atherosclerosis ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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  • 2
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    Mineralogy (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Mineralogy includes thirteen chapters that discuss the methodology of specific mineralogical methods, the composition of minerals from different igneous rocks, and the composition of minerals from different sedimentary rocks.It contains detailed mineralogical studies from Africa, Asia, and Europe. Chapters present different scientific mineralogical methods and detailed descriptions of minerals from different magmatic and sedimentary rocks.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNV Chemistry of minerals, crystals and gems
    Language: English
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  • 3
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    Benzimidazole (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Benzimidazole is a comprehensive survey of the known and new methods of benzimidazole synthesis, the spectral and theoretical aspects of existing benzimidazole derivatives, and the anticancer properties of a new class of benzimidazole derivatives. This book examines aspects and newer mechanisms of benzimidazoles containing heterocyclic moiety. Chapters report on anticancer properties of benzimidazole derivatives, novel methods of synthesis of benzimidazoles, versatile nature of the benzimidazoles, spectral and theoretical studies of benzimidazole derivatives, and medicinal importance and pharmacological aspects of benzimidazole derivatives.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 4
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    Recent Updates on Multiple Myeloma (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book provides a comprehensive overview of multiple myeloma. It is organized into three sections with chapters addressing topics such as diagnosis, risk stratification, and management of multiple myeloma; treatment of multiple myeloma at diagnosis and at relapse; management of disease complications; and stem cell therapies, including autologous and allogeneic hematopoietic stem cell transplantation with a focus on autologous grafting using non-cryopreserved stem cells and performance of stem cell transplantation in outpatient settings.
    Keywords: cryopreservation ; chemotherapy ; quality of life ; hematopoietic stem cell transplantation ; monoclonal antibodies ; adverse effects ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 5
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    Topics in Heart Failure Management (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: This textbook represents a short update on original aspects of heart failure. It covers topics of heart failure management such as prevention, drug monitoring after heart transplant, and the critical care approach. There are also chapters on less common facets of this syndrome such as prevalence and features in a specific African region and the complexity of telemedicine in heart failure. In summary, it will be a valid adjunct to more exhaustive textbooks already available.
    Keywords: artificial intelligence, diabetes mellitus, heart transplantation, telemedicine, critical care, chronic disease ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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  • 6
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    Green Chemistry (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Green Chemistry - New Perspectives is at the frontiers of this continuously evolving interdisciplinary science, and publishes research that attempts to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The book covers all aspects of green chemistry, including chemical synthesis, nano synthesis, eco-friendly processes, biomass, extraction techniques, environmental remediation, and energy, making it a unique reference resource. This will continue to encourage scientists around the world to develop novel synthetic methods or improve the existing ones to circumvent some of the problems and favours all aspects of green chemistry. This book is intended for academia, professionals, scientists, as well as graduate and undergraduate students without any geographical limitations.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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  • 7
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    Heart Transplantation (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: One of the most challenging scientific steps of the modern era has been the ability to replace, functionally or anatomically, the failing heart, and in December 2017 we celebrated the 50th anniversary of the world's first human heart transplant. Despite a long and troubled hystory, heart transplantation has dramatically expanded over time, and is currently the "gold standard" solution in terms of treatment of refractory end-stage heart failure. Thanks to the contributions by well-known experts in the field, the goal of this book is to provide a framework for successful transplant program development and management. The text reflects the global collective efforts of those who have dedicated countless energy to achieving a better understanding of the details that will ultimately yield better outcomes in terms of teamwork.
    Keywords: congenital heart disease, lvad, mechanical circulatory support, rituximab, epidemiology, heart failure ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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  • 8
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    Cancer Management and Therapy (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: There are many different types of cancer. Some are very common; others are rare. Having some similar features, each cancer has its own characteristics and symptoms, which vary according to the type of cancer and where it is in the body. The treatment selected may be influenced by the patient's age, concurrent health problems, life expectancy, characteristics of the individual's cancer, the patient's goals of treatment, and the bias of the treating physician. In preparing this book, we have considered and reflected on the concept of the recent advances in cancer management and therapy as well as molecular applications in cancer therapy. The readers can find detailed information about the treatment and management of specific cancers in these book chapters.
    Keywords: breast cancer, immunotherapy, apoptosis, colorectal cancer, lung cancer, targeted therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 9
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    Primary Intracranial Tumors (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book covers specific chapters with fundamental and current concepts about the main primary intracranial tumors, aimed at general neurosurgeons, neurologists, oncologists, radiotherapists, and residents. They are everyday situations from the subspecialist routine that can become challenging for professionals outside referenced centers or working alone.
    Keywords: glioblastoma, magnetic resonance imaging, gliomas, immunotherapy, biomarker, chemotherapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 10
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    Free Radicals and Diseases (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: The current volume entitled, "Free Radicals and Diseases" integrates knowledge in free radical-associated diseases from the basic level to the advanced level, and from the bench side to bed side. The chapters in this book provide an extensive overview of the topic, including free radical formations and clinical interventions.
    Keywords: Oncology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 11
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    Current Perspectives on Cardiomyopathies (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: Advances in the understanding of cardiomyopathies and the growth of cardiology have paralleled one another. Over the years, many classification methods have been developed for cardiomyopathies based on aetiology, structural models and the functional approach. The new concepts and events that have occurred in cardiology generally and in cardiomyopathies specifically are sufficient changes to justify this book. Developments in cardiomyopathies have advanced at a rapid rate, largely because of the progress that has been made in instrumental analysis and the integration of clinical cardiology with other fields of basic research. The material in this book encompasses and blends the knowledge recently acquired in genetics, pathology and physiology with the practical matters of diagnosis and treatment.
    Keywords: heart failure, cardiomyopathy, coronary artery disease, echocardiography, sudden cardiac death, myocardial infarction ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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  • 12
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    Challenges in Pancreatic Cancer (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Pancreatic cancer is one of the most lethal solid organ tumors with a poor five-year survival rate despite current oncological advances. The early and proper diagnosis of pancreatic cancer is of great importance for the improvement of the overall prognosis. This book provides an overview of the current challenges and states of pancreatic cancer and pancreatic neuroendocrine tumors, including information on diagnostic tools, treatment strategies, and mechanisms of pancreatic cancer therapy resistance.
    Keywords: immunotherapy, tumor microenvironment, irreversible electroporation, therapy, computer-assisted surgery ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 13
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    Analytical Liquid Chromatography (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book consists of several selected chapters on important subjects in modern high-performance liquid chromatography (HPLC) and ultra-performance liquid chromatography (UPLC). The content addresses aspects related to both improvements in the mainstream HPLC/UPLC technology and utilization, as well as developments of exploratory new materials and equipment. The book presents useful details about the presented subjects as well as describes new applications and/or relevant case studies for each subject. It is addressed to a large audience of analytical chemists involved in separation science. Each chapter is authored by scientists with considerable field and academic experience.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
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  • 14
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    Cardiovascular Risk Factors in Pathology (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: This book provides a broad overview of the molecular mechanisms associated with relevant and significant cardiovascular conditions that continue to plague humanity. It also discusses potential and promising therapeutic avenues targeted at addressing these conditions. The overarching goal of this multifaceted work is to entice future and current members of the scientific community to direct their endeavors towards improving our current knowledge of cardiovascular disease conditions and curb their impact on our everyday lives.
    Keywords: inflammation, oxidative stress, heart failure, autophagy, atherosclerosis, metabolism ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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  • 15
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    Cervical Cancer (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book entitled Cervical Cancer - Screening, Treatment and Prevention Universal Protocols for Ultimate Control is the fourth successful endeavor of the Editor with InTech publisher. The four books serve as four pillars in cervical cancer control, globally. This book is unique and sensational. Public health "topics" are assuming a status of "phenomenon," through deliberations and research. Screening is riddled with global limitations of availability, affordability, acceptability, and accessibility. The treatment of precancers has questionable efficiency. Prevention is costly with the inclusion of HPV vaccine. This book helps to find the solutions. The authors, editor, and InTech publisher wish the readers a pleasant and purposeful reading. This book is a "readers' feast," "receivers' choice," and "respondents' delight." Enjoy and treasure the international facts and flavors.
    Keywords: human papillomavirus, biomarker, microbiome, carcinogenesis, radiation, genetic variation ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 16
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    Recent Advances in Chemical Kinetics (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Recent Advances in Chemical Kinetics provides a comprehensive overview of several types of chemical reactions. It includes six chapters that discuss solvent catalysis, customized flow reactors, p-conjugation in kinetics, kinetics of autoxidation, molecular chameleon for cations and anions, and internal clocks of atoms.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
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  • 17
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    Oncogenes and Carcinogenesis (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis.
    Keywords: breast cancer, colorectal cancer, lung cancer, mirna, dna repair, arsenic ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 18
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    Cardiomyopathy (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: Cardiomyopathies are diseases of the heart muscle with diverse etiologies ranging from myocarditis to gene mutations. They are classified according to morphology and function, and then further categorized based on whether they are familial or non-familial and based on specific etiologies. This book examines the various cardiomyopathies, including arrhythmogenic cardiomyopathy, hypertrophic cardiomyopathy, and dilated cardiomyopathy, as well as their genetic basis.
    Keywords: heart failure, genetics, sudden cardiac death, hypertrophic cardiomyopathy, arrhythmias, dilated cardiomyopathy ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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  • 19
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    Pheochromocytoma, Paraganglioma and Neuroblastoma (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Pheochromocytoma, paraganglioma and neuroblastoma are the most common neural crest-derived tumors in adults and children, respectively. These neoplasms are associated with significant morbidity and mortality. Some international studies currently underway are researching and evaluating the presence of any similarities and differences between these tumors. Hopefully, future results will reveal several potential novel genes and pathways that might have major roles in the pathogenesis and progression of these neoplasms. This book discusses epidemiology, genetics, and treatment of these malignancies.
    Keywords: chemotherapy, metastasis, mirna, dna methylation, epigenetic, laparoscopic surgery ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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  • 20
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    Coronary Artery Bypass Grafting (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-02-15
    Description: The book “Coronary Artery Bypass Grafting” is an excellent update for health care professionals, taking care of patients who are suffering from severe coronary artery disease. The 8 chapters in this book were written by experts in their topics. The first section describes the perioperative management. The second section describes the details of various surgical techniques. The last section discusses the superiority of CABG vs PCI. I believe this book will suffice the interests of our readers.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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  • 21
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    Cancer Bioinformatics (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book discusses the application of bioinformatics in cancer disease management. It covers general aspects of cancer as a disease but also as a success story in the translation of omics data in clinical settings. It provides an overview of the specific applications of bioinformatics tools in cancer epidemiology, prevention, and screening and in the identification of novel genetic and molecular biomarkers involved in cancer development. This is accomplished through the inclusion of numerous examples of the use of bioinformatics in precision oncology.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 22
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    Glioblastoma (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Glioblastoma (GBM) is a common and aggressive brain cancer with features of necrosis and endothelial proliferation in the histopathologic examination. Its presentation and management depend on tumor location, size, grade, and underlying histopathological characteristics. GBM tumors have clinical features of increased intracranial pressure, focal neurological deficits, or seizures (generalized or partial) with rapid progression. This book discusses GBM and its diagnosis, treatment, and management.
    Keywords: immunotherapy ; chemotherapy ; glioma ; genetics ; biomarker ; elderly ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 23
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    Angiography (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: Atherosclerotic cardiovascular disease is still the most common cause of death among adults. Its prevalence is increasing in developing countries and despite all advances in both diagnostic tools and treatment modalities, it is still very common in the developed world. Obesity, diabetes mellitus, hypercholesterolemia, and overuse of dietary salt play a pivotal role in increased cardiovascular morbidity and mortality worldwide. Current clinical efforts are mainly focused on the diagnosis and treatment of myocardial infarction. In this book we provide epidemiological data on myocardial infarction and atherosclerotic cardiovascular disease, current diagnostic biochemical tests, and management strategies. A specific patient group, children, experiencing myocardial infarction is also addressed. Current advancements in the management of myocardial infarction have decreased the morbidity and mortality from atherosclerotic cardiovascular disease and especially myocardial infarction; however, further progress can be achieved by the prevention of atherosclerotic processes by focusing on the early stages of the disease.
    Keywords: atherosclerosis, manufacturing, kidney transplantation, bifurcation, renal, digital image processing ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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  • 24
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    Hepatocellular Carcinoma (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated, imaging methods being considered as sufficient diagnostic tools. Molecular characterization remains desirable, since chemotherapeutic agents still have limited applicability. In light of recent diagnostic advancements and novel therapeutic solutions, it is our belief that a comprehensive update on recent paradigm shifts and interesting upcoming developments is highly needed.
    Keywords: cancer, targeted therapy, obesity, immunotherapy, metabolism, microrna ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 25
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    Redox Chemistry (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Redox reactions are involved in biochemistry, energy, corrosion, and much more. In both biology and electrochemistry, the redox reaction is complex and varied. For example, redox shuttles in supercapacitors show aspects of molecular electrochemistry applied to electrode porosity. In pseudocapacitors, the formalism associated with their electrochemical response requires investigation and formalism. Similarly, the simple definition of redox potential opens fundamental questions about its measurement in solutions without supporting salts. This book illustrates the variety of redox reactions in its examination of the importance of redox molecules in the development of new electrical energy storage devices.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRH Electrochemistry and magnetochemistry
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  • 26
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    Endothelial Dysfunction (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-09-05
    Description: The endothelium is a “fluid” and an ever-evolving biological component of the cardiovascular system. It plays important roles in regulating immunology, inflammation, and angiogenesis, among other functions. This book provides a comprehensive review of the endothelium, with a focus on novel aspects of endothelial dysfunction and its treatment.
    Keywords: inflammation ; cardiovascular diseases ; nitric oxide ; polyphenols ; precision medicine ; vegf ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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  • 27
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    Blood Pressure (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: Since the discovery of blood pressure by Stephen Hales in 1733, scientific interest in blood pressure regulation, particularly in hypertensive population, has not lost its popularity. The importance of the interactive effects of blood pressure shifts in different clinical conditions is well understood. We know many contributing factors regulate the pressure of the blood within the arteries. However, crucial blood pressure control and the exact mechanisms involved are still under debate. The present book aims to cover blood pressure from its measurement to various factors of its control with valuable contributions from different authors, in the light of contemporary data, from bench to bed.
    Keywords: hypertension, pathophysiology, oxidative stress, pregnancy, drug resistance, echocardiography ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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  • 28
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    Phase Equilibria With Supercritical Carbon Dioxide (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: We are living in a critical time, both for humanity and the planet, which has led us to look for more sustainable formulas to interact with the environment. One of the important changes in the design and operation of chemical processes is the search for environmentally friendly technologies. Supercritical carbon dioxide has been revealed as a promising environmentally friendly solvent that is energy efficient, selective and capable of reducing waste, making it a promising alternative to conventional organic solvents. However, reliable and versatile mathematical models of phase equilibrium thermodynamics are needed for the use of supercritical carbon dioxide in process design and viability studies. This book reviews experimental procedures for obtaining high-pressure phase equilibria data and describes the phase diagrams of binary mixtures and some thermodynamic models capable of determining the conditions of phase equilibria at high pressures. These concepts are applied to the components of the transesterification reaction of rac-2-pentanol with a vinyl ester, which is important in the pharmaceutical industry because (S)-2-pentanol can be obtained as a reaction product. This product is a key intermediate in the synthesis of drugs against Alzheimer’s disease.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry
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  • 29
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    Tumor Metastasis (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Metastasis is the major cause of cancer-related death. It is a multistep process. The mechanism underlying metastasis is complicated and poorly understood. Recent advances in tumor metastasis research have led to improved diagnosis and clinical management of cancer. However, new strategies on metastasis treatment are urgently needed, especially the novel biomarkers discovery and targeted therapy. This book is designed to present the most recent advances in tumor metastasis.
    Keywords: cancer, breast cancer, drug delivery, exosomes, extracellular matrix, ovarian cancer ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 30
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    Melanoma (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Melanoma is an aggressive type of cancer for which treatment has dramatically evolved during the last 15 years, improving response and survival figures. This book, written by a diverse panel of experts, presents a description of the most relevant aspects of the epidemiology, diagnosis, local treatment, prognostic biomarkers and treatment for advanced disease, including the most recent research on novel molecules that are either approved or are undergoing clinical development. It includes insights on such challenging topics as when immunotherapy should be started in BRAF mutant patients, or which is the most appropriate treatment algorithm in those cases, as well as how to handle difficult and poor-prognosis melanoma cases, such as patients with brain metastases or patients with the uveal disease.
    Keywords: immunotherapy ; targeted therapy ; histopathology ; cancer ; radiotherapy ; immune checkpoint inhibitors ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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  • 31
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    Human Skin Cancers (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.
    Keywords: biomarkers, immunotherapy, chemotherapy, melanoma, targeted therapy, squamous cell carcinoma ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Liver Cancer (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a number of putative therapeutic targets, including signal transduction pathways, metabolic and epigenetic alterations in tumor cells, the tumor microenvironment, the gut microbiome, and functions of immune effector cells. Given the multi-step nature of most cancers, including HCC, future drug development will most likely require combination therapies that will simultaneously target multiple steps in hepatocarcinogenesis.
    Keywords: hepatocellular carcinoma ; liver cirrhosis ; inflammation ; biomarkers ; immunotherapy ; gene expression ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Advances in Precision Medicine Oncology (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin’s drug resistance and critical side effects.
    Keywords: immunotherapy, doxorubicin, cancer immunotherapy, cancer, optimization, nanoparticles ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Cardiotoxicity (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.
    Keywords: oxidative stress, mitochondria, doxorubicin, anthracycline, inflammation, biomarkers ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Covalent Organic Frameworks (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: In recent decades, artificial porous structures have attracted increasing enthusiasm from researchers inspired by the fascinating molecular pores in nature and their unique biological functions. Although substantial achievements in porous materials have been realized, the construction of topologically designed pores is still challenging. Recently, the emergence of covalent organic frameworks (COFs), which are constructed based on organic and polymer chemistry, has made it possible to design artificial pores with controlled pore size, topology and interface properties. COFs are crystalline porous materials constructed by the precise reticulation of organic building blocks via dynamic covalent bonds. Distinct from non-covalent interactions which tend to produce isostructures, covalent bonds enable accurate pore design owing to their predetermined reaction pathways. In addition, the appropriate polycondensation of organic building units enables the formation of extended two-dimensional (2D) and three-dimensional (3D) polymer architectures with periodically ordered skeletons and well-defined pores. With their large surface area, tailorable structures, and tunable chemistry, COFs are regarded as potentially superior candidates for various applications including catalysis, energy storage and conversion, mass transport and biotechnology. This book examines the historic achievement of COFs, providing clear and comprehensive guidance for researchers on their structural design, synthetic protocols and functional exploration.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
    Language: English
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    Fluoride (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Fluoride covers a continuum of topics that are frequently studied in the broad area of fluoride (F) research. It provides an overview of the primary sources of environmental fluoride in typical high-fluoride environments and demonstrates the transitions and transformations that emerge and culminate in hydro-geochemical interactions that result in fluoride-fouling of large portions of the world’s water and agricultural resources. This way, the book pinpoints the connection between F enrichment of water sources and the prevalence of endemic fluorosis in certain areas of the world. In order to contribute to a better understanding of the global fluoride problem, new fluoride detection and quantification technologies are proposed with an in-depth analysis of emerging trends in the use of portable user-friendly devices in point-of-use measurements of water fluoride. This has been presented against the backdrop of a robust overview of traditional fluoride quantification methodologies that are still in wide application among the scientific communities. In addressing fluoride toxicities, which are not limited to dental and skeletal dilapidations, the authors have explored the role of natural antioxidants in ameliorating physiological fluoride-induced noxious effects in mammalian systems. Nonetheless, since community dependence on high-fluoride water due to a lack of alternative clean water sources remains to be the principal pathway of human fluoride over-exposure, a review chapter on F mitigation techniques applied all over the world is incorporated aiming at providing a succinct overview of water defluoridation techniques and strategies being used to combat the impacts of human F overexposure around the globe. Since every cloud has a silvery lining, the possibility of using ammonium fluorides as a novel reagent in mineral processing has been considered convenient industrial fluorinating agents, which present the possibility of complete regeneration that is not afforded by the reagents presently used in decomposing silicon component of the ores.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
    Language: English
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    Recent Developments in Myelodysplastic Syndromes (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book deals with the rapid progress in the area of myelodysplastic syndromes (MDS). MDS are a group of age-associated heterogeneous malignant bone marrow stem cell disorders. MDS are characterized by ineffective hematopoiesis, which leads to refractory cytopenias and to clonal instability. Patients with MDS have myeloid dysplasia, intramedullary apoptosis and an increased risk of transformation to acute myeloid leukemia (AML). The use of next generation sequencing has allowed for the identification of molecular mutations in several genes in about 90% of MDS patients. Several mutations will likely be incorporated into future prognostic scoring systems for MDS. About 50% of MDS cases are characterized by the presence of cytogenetic abnormalities. The correct morphological and cytogenetic analysis interpretation plays an important role in diagnosis and prognosis of these disorders. Cell death and an inflammatory gene signature are associated with MDS. Better understanding of the genetic and molecular mechanisms of MDS pathogenesis provides an opportunity for new treatment strategies to be developed. Promising novel therapies targeting pathophysiological mechanisms of MDS are being studied but the drugs currently used in MDS therapy remain limited. The only curative therapy for MDS is allogeneic hematopoietic stem cell transplantation. Recent advances in strategies to minimize transplant-related toxicity make this treatment possible for more MDS patients who are sufficiently fit.
    Keywords: cytokines, pathogenesis, micrornas, dendritic cells, behçet’s disease, vasculitis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Update on Multiple Myeloma (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book is a comprehensive overview of the recent developments in the clinical and research fields of multiple myeloma. It is divided into three main sections that cover a wide range of topics, including: epidemiology and pathogenesis of the disease, genetic targets and pathways, resistance to novel therapies, angiogenesis and anti-angiogenesis, hematopoietic stem cell transplantation, role of radiology and radiotherapy in myeloma, infectious complications, and management of multiple myeloma in resource-poor countries.
    Keywords: hematopoietic stem cell transplantation, monoclonal antibodies, novel therapies, epidemiology, risk factors, angiogenesis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Exploring Chemistry with Pyridine Derivatives (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book discusses the chemistry and applications of pyridine derivatives. The library of pyridine derivatives is growing steadily with numerous synthetic analogues already described and the identification of new, naturally occurring pyridine-based compounds. The book includes ten chapters organized into two parts. The first part focuses on the numerous types of reactions that arise from pyridine derivatives. The second part examines the pharmaceutical applications of pyridine derivatives as well as their usefulness as sensors for metal cations and extracting agents for platinum group metals.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
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    Dosimetry (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The book discusses multiple issues associated with modern dosimetry in physics and treatment planning and how investigators from diverse world centers and institutions approach problem-solving in these important areas. It examines topics including pretreatment validation and factors affecting reference dosimetry. It also addresses unique issues affecting pediatric populations as well as the modern role of thermoluminescence validation. Several chapters discuss intensity modulation, including defining modern problems associated with both treatment planning and the definition of tumor and normal tissue contours. Furthermore, the book examines the role of imaging as both a vehicle to define tumor targets and normal tissue as well as a tool for dose validation.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRL Nuclear chemistry, photochemistry and radiation
    Language: English
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    Advances in Soft Tissue Tumors (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: This book aims to foster collaboration between world-class bench scientists and clinicians in the fields of oncology, surgery, and pathology as they come together to highlight the complexity and diversity of soft tissue tumors as well as recent advances in their diagnosis and clinical management.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Novel Implications of Exosomes in Diagnosis and Treatment of Cancer and Infectious Diseases (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: The aim of this book is to provide an overview of the importance of exosomes in the biomedical field, which involves in novel implications of exosomes in diagnosis and treatment of cancer and infectious diseases. The book would definitely be an ideal source of scientific information of exosomes to researchers and scientists involved in biomedicine, biology, and other areas involving cancer and infectious diseases.
    Keywords: biomarkers, extracellular vesicles, pathogenesis, multiple myeloma, liquid biopsy, endothelial cells ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Pericarditis (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-09-05
    Description: This book is not about clear cases of acute and chronic pericarditis, but about unresolved issues not covered by current clinical guidelines that frequently create unexpected difficulties in the management of the disease in routine clinical practice. Here we discuss different kinds of diagnostic management from conventional echocardiography to advanced visualization procedures, such as magnetic resonance imaging and biopsy procedures, with the aim of clearly elucidating novel approaches to establishing the presence of the disease, predicting its natural course and determining its management. Although pericarditis of unknown etiology is frequently encountered in clinical practice, specific serological markers and culture tests are not regarded as final decision tools to thoroughly establish plausible causes of the disease in patients without clear backgrounds, signs and symptoms of heart failure, and concomitant conditions. In this respect, endocardial and pericardial biopsy, combined visualization procedures, such as contrast-enhanced magnetic resonance imaging with 3D-computer tomography modeling of cardiac function, are the next steps in contemporary management. The surgical approach, along with clear descriptions of patients’ enrollment and predicted outcomes, are also described in this book.
    Keywords: covid-19 ; inflammation ; heart failure ; surgery ; infection ; tuberculosis ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Cholesterol (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: "What is this cholesterol?" In this book entitled "Cholesterol- Good, Bad, and the Heart" now you got the answers given by the experts in the field. Moreover, you can explore more by reading the references/citations given in the articles of each chapter. It is still an emerging field and lot more is being discovered. You will be amazed how much knowledge is already there in this book on cholesterol. You will realize that cholesterol is an essential and extremely important building block of cell membranes and thus serves vital functions in the body. I believe this book will be incredibly powerful and useful in teaching to give new perspectives on cholesterol.
    Keywords: cardiovascular disease, hypertension, atherosclerosis, cytoskeleton, skeletal muscle, actin ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Lung Cancer (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Lung cancer continues to be the leading cause of cancer mortality worldwide among both men and women. Recent advances in prevention, screening and management in the past decade have led to significant improvements in survival and quality of life. Local treatments like minimally invasive surgery, radiotherapy, and image-guided ablation have contributed to improving the effectiveness and tolerability of potentially curative treatments in early-stage, locally advanced, and oligometastatic/oligoprogressive disease. Chemotherapy, targeted therapy, immunotherapy, and palliative local therapy options have expanded rapidly, with new regimens showing improved outcomes even for those with widely metastatic disease. This book comprehensively reviews the evidence that has driven personalized medicine, based on a variety of multidisciplinary perspectives by international lung cancer experts.
    Keywords: minimally invasive surgery, robotic surgery, immunotherapy, radiotherapy, mirna, liquid biopsy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Desalination (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The book comprises 14 chapters covering all the issues related to water desalination. These chapters emphasize the relationship between problems encountered with the use of feed water, the processes developed to address them, the operation of the required plants and solutions actually implemented. This compendium will assist designers, engineers and investigators to select the process and plant configuration that are most appropriate for the particular feed water to be used, for the geographic region considered, as well as for the characteristics required of the treated water produced. This survey offers a comprehensive, hierarchical and logical assessment of the entire desalination industry. It starts with the worldwide scarcity of water and energy, continues with the thermal - and membrane-based processes and, finally, presents the design and operation of large and small desalination plants. As such, it covers all the scientific, technological and economical aspects of this critical industry, not disregarding its environmental and social points of view. One of InTech's books has received widespread praise across a number of key publications. Desalination, Trends and Technologies (Ed. Schorr, M. 2011) has been reviewed in Corrosion Engineering, Science & Technology – the official magazine for the Institute of Materials, Minerals & Mining, and Taylor & Francis's Desalination Publications. Praised for its “multi-faceted content [which] contributes to enrich it,” and described as “an essential companion...[that] enables the reader to gain a deeper understanding of the desalination industry,” this book is testament to the quality improvements we have been striving towards over the last twelve months.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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    Cancer Metastasis (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: Cancer mortality and morbidity are primarily brought on by metastasis. The ability of neoplastic cells to spread and colonize distant tissues is their most dangerous trait. Most malignancies are curable when they are detected early and have not spread outside of the original tissue. However, cancer is frequently incurable when tumor cells have created colonies elsewhere. Thus, the book content This book provides comprehensive information on cancer metastasis, along with references to specific cancer cases. The topics discussed include invasion by perturbation of cell-cell and cell-matrix adhesion, matrix degradation, motility, intravasation, extravasation, metastatic colonization, metastasis and angiogenesis. Molecular mechanisms, the metastatic process, and palliative bone metastasis therapy are also considered.
    Keywords: breast cancer ; immunotherapy ; epigenetics ; lung cancer ; extracellular vesicles ; targeted therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Lung Cancer (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Among the deadliest type of cancers, lung cancer faces several challenges in diagnosis and treatment: late diagnosis and misdiagnosis, inadequate tumor sampling, and resistance development to current therapies, among others. Together with advances in the understanding of molecular features, factors, and mechanisms involved in initiation and tumor progression, important improvements have occurred in diagnostics and therapeutics in the shape of advances in molecular genotyping, procedures for sampling, new potential, and less invasive sources of samples for the diagnosis and development of new targeted therapies. The aim of this book is to provide an exciting read on strategies in the diagnosis and therapy of lung cancer.
    Keywords: immunotherapy, biomarker, metabolomics, epigenetic, cancer stem cells, methylation ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Advanced Gas Chromatography (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Progress in agricultural, biomedical and industrial applications' is a compilation of recent advances and developments in gas chromatography and its applications. The chapters cover various aspects of applications ranging from basic biological, biomedical applications to industrial applications. Book chapters analyze new developments in chromatographic columns, microextraction techniques, derivatisation techniques and pyrolysis techniques. The book also includes several aspects of basic chromatography techniques and is suitable for both young and advanced chromatographers. It includes some new developments in chromatography such as multidimensional chromatography, inverse chromatography and some discussions on two-dimensional chromatography. The topics covered include analysis of volatiles, toxicants, indoor air, petroleum hydrocarbons, organometallic compounds and natural products. The chapters were written by experts from various fields and clearly assisted by simple diagrams and tables. This book is highly recommended for chemists as well as non-chemists working in gas chromatography.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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    Electrocatalysis and Electrocatalysts for a Cleaner Environment (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: This book discusses electrocatalysis and electrocatalysts for energy, water electrolysis, water treatment, CO2 conversion, and green chemistry. It reviews various electrocatalysts and their properties and electrochemical performances. The first section of the book covers topics in direct alcohol fuel cells including Pt-based electrocatalysts as non-carbon electrode support materials and the development of electrocatalysts for direct methanol fuel cells. The second section of the book covers various topics in electrocatalysis and electrocatalysts for a cleaner environment, including electrocatalysts for the conversion of CO2 to valuable products and SYNGAS, electrocatalysts for water electrolysis, and much more.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRH Electrochemistry and magnetochemistry
    Language: English
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    Advances in Extra-corporeal Perfusion Therapies (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: Extracorporeal membrane oxygenation (ECMO) has evolved into an exciting and valuable tool to assist in the management of patients experiencing cardiogenic shock, severe acute respiratory failure, or often a combination of both. While outcomes remain less than ideal, they continue to improve with team experience, better patient selection, and a growing understanding of the nuances of managing patients who require mechanical circulatory support. Patients requiring ECMO are often extremely sick and have complex problems - initiating therapy before the development of end-organ damage is critical. Without doubt, teamwork, guidelines, and protocols are cornerstone concepts for clinical and program success - all topics that are emphasized in this text. The goals of this text are to further outline topics that help address some of the key challenges providers face when considering and applying extracorporeal support therapies to the evolving spectrum of acutely ill patients.
    Keywords: heart failure, ecmo, cardiogenic shock, extracorporeal membrane oxygenation, mechanical circulatory support, sepsis ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Aortic Stenosis (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: As the most common cardiac valve disease, aortic stenosis is frequently encountered by healthcare providers in clinical practice. It may be suspected from a cardiac murmur found at a routine clinical exam, signs on ECG, heart failure, or an episode of syncope or arrhythmia. Echocardiography as well as other imaging tools provide information about the degree of severity of the stenosis. Nevertheless, careful judgement of potential symptoms is crucial. When it comes to treatment, a catheter-based approach has emerged as the preferred option in many cases, even though open-chest surgery is still standard treatment. Regardless of treatment modality, a multidisciplinary team is needed to provide optimal management of patients with aortic stenosis. This book provides all the necessary information on aortic stenosis, including etiology, diagnosis, treatment, and follow-up.
    Keywords: epidemiology, surgery, genetics, echocardiography, hemodynamics, dog ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Surfactants and Detergents (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Surfactants are ubiquitous and have applications in diverse areas, including food, cosmetics, detergents, lubricants, enhanced oil recovery (EOR), and targeted drug delivery systems. Their wide diversity of applications owes to their unique structure, namely, a hydrophilic and a hydrophobic group present in the same molecule. Although most surfactants used industrially are synthetic, there is a growing need for natural surfactants, as the latter is obtainable from renewable sources and are less toxic and highly biodegradable in contrast to their synthetic counterparts. This book is a compilation of interesting articles by various experts that cover various applications of both synthetic and natural surfactants.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRC Colloid chemistry
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    Advances in Chemical Sensors (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: The chemical sensor plays an essential role in the fields of environmental conservation and monitoring, disaster and disease prevention, and industrial analysis. A typical chemical sensor is a device that transforms chemical information in a selective and reversible way, ranging from the concentration of a specific sample component to total composition analysis, into an analytically useful signal. Much research work has been performed to achieve a chemical sensor with such excellent qualities as quick response, low cost, small size, superior sensitivity, good reversibility and selectivity, and excellent detection limit. This book introduces the latest advances on chemical sensors. It consists of 15 chapters composed by the researchers active in the field of chemical sensors, and is divided into 5 sections according to the classification following the principles of signal transducer. This collection of up-to-date information and the latest research progress on chemical sensor will provide valuable references and learning materials for all those working in the field of chemical sensors.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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    Advanced Concepts in Endocarditis (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: The concept of endocarditis has evolved significantly over the years. While initially associated with patients with advanced co-morbidities, such as renal failure and chronic immunosuppression, endocarditis now spans many diverse disciplines. As such, the importance of advanced diagnostic imagining tools, a better understanding of the pathophysiology of not only the infectious (and non-infectious) disease process but also of cardiac structural abnormalities, and the growing literature on management cannot be underemphasized. This book broadens our collective understanding of the spectrum of diagnostic and therapeutic challenges that all areas of medicine must appreciate when faced with the challenging clinical problem of endocarditis.
    Keywords: heart failure, echocardiography, cancer, infection, hypertension, biofilm ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Atrial Fibrillation (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-02-15
    Description: Atrial Fibrillation - Diagnosis and Management in the 21st Century provides the most up-to-date information about the most common cardiac arrhythmia in humans, atrial fibrillation. In this rapidly developing field of medicine, the book helps to answer the question, “Which treatment should I choose for which patient?” The book also discusses new drugs, applications and interventions in the field. The 12 chapters are written from a variety of viewpoints by authors who use solid, scientific and contemporary approaches to practical questions.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Cardiac Diseases and Interventions in 21st Century (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: What should a book on cardiac diseases tell us about? We are not cardiologists in most instances, nor ordinary patients preparing to be catheterized. This book tries to explain to the average medical reader about the causes, diagnostic advances, and therapeutic opportunities in the context of cardiac diseases in the modern era. The topics covered in this project will enlighten research pathways while rendering clinicians practical solutions to everyday problems in recognition and management of these entities. In brief, students, nurses, paramedical personnel, researchers, junior doctors, and experienced practitioners will benefit from this book when translating theory into practice.
    Keywords: cardiopulmonary resuscitation, obesity, diabetes, simulation, risk factors, cardiac resynchronization therapy ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Distillation Processes (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Distillation is an important separation technique that has been used for many centuries to exploit the volatility differences between components in a mixture. The distillation process has many variations and applications. This book includes two sections on desalination and reactive distillation. It discusses desalination in the processes of solar and membrane distillation, with a focus on the reduction of energy costs to obtain potable water. It also discusses reactive distillation, which can be used in some cases to reduce the power duty in the separation process by using the reaction heat directly in the separation. The book includes cases of mathematical modeling, simulation, and optimization of the distillation process.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry
    Language: English
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    Esophageal Cancer and Beyond (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: Human life relies on two basic supplies from nature: oxygen and food. Oxygen can be utilized directly, but food has to go through a process of digestion to become usable nutrients. The esophagus represents the beginning of this long journey. Because of its critical location, esophageal cancer is one of the deadliest malignancies in the world, and furthermore its incidence has been rising steadily year after year while other cancers are declining. It is predicted that by the year 2035 the esophageal cancer population will increase by 77.4% and become one of top global concerns. This book covers many aspects of esophageal cancer, through which we hope to raise the awareness of professionals as well as non-professionals about this disease.
    Keywords: immunotherapy, regenerative medicine, tumor microenvironment, gerd, laryngectomy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Heart Valve Surgery (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-09-05
    Description: This year marks the 70th anniversary of the first artificial heart valve, which was implanted in 1952 by Charles Hufnagel to treat a 30-year-old woman with severe aortic regurgitation in an era when the concept of direct valve repair or replacement did not exist. It is remarkable how far we have come since then in terms of managing heart valve disease, not only in terms of advances in surgical techniques or choice of prostheses for different valve pathology but also in terms of transcatheter therapy and minimally invasive surgical approaches. This book reviews important and major milestones in managing different valve pathologies with a focus on aortic and tricuspid valve diseases.
    Keywords: aortic valve ; minimally invasive surgery ; endocarditis ; mitral valve ; tricuspid valve ; left ventricular hypertrophy ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Hypertension (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-02-15
    Description: This book, “Hypertension - An Update”, covers diverse topics, such as an overview of mechanisms, MRI as a diagnostic tool, the role of stem cells in elucidating molecular mechanisms and tools for hypertension research and therapeutics. It also covers epidemiology and the role of Vitamin D in hypertension. These varied subjects will be of keen interest to clinicians and research scientists.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Peripheral T-cell Lymphomas (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: In this book the reader will find a collection of chapters written by different research teams describing different aspects of peripheral T-cell lymphoma pathobiology, classification, and treatment. This work is mainly addressed to researchers already working in this area, but it is also accessible to anyone with a scientific background who desires to have an updated overview of the recent progress in this domain. It will also be valuable to scientists and physicians who have become newly involved in this field. Each chapter is self-contained and can be read independently of the others. This book intends to provide highlights of the current research as well as the current gold standards for diagnosis and treatment of these diseases, showing the recent advances in the personalized approach to T-cell derived lymphomas.
    Keywords: epigenetics, genomics, targeted therapy, precision medicine, transcriptomics, tyrosine kinase inhibitors ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Cardiomyopathies (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Cardiomyopathies are the most featured cardiac pathologies in the twenty-first century, that threaten public health and burden healthcare budgets. This book is composed of the main topics on pathophysiology, general forms and specific types of cardiomyopathies and it also introduces new research in the field. Specific forms with or without genetic inheritance are discussed separately to attract the readers' attention on these topics. Well-known medical follow-up strategies occur ineffective at the end-stage heart failure, however, new surgical approaches can be an alternative for these patients to get a chance at the last crossroad and to improve their life quality and survival and also to gain or prolong time until possible heart transplantation.
    Keywords: heart failure, cardiomyopathy, sudden cardiac death, hypertrophic cardiomyopathy, dilated cardiomyopathy, inflammation ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Colorectal Cancer (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: Colorectal cancer is the third most common cancer diagnosed in both men and women worldwide. This book examines state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. It emphasizes the importance of a multidisciplinary approach involving multiple specialties, including surgery, gastroenterology, radiology, biology, oncology, radiotherapy, nuclear medicine, and physiotherapy.
    Keywords: colon cancer, immunotherapy, mri, targeted therapy, mortality, imaging ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Aortic Stenosis (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-02-15
    Description: Aortic stenosis is one of the most common and serious valvular diseases in the elderly. Its prevalence increases with age and treatment is always surgical. This book provides a comprehensive overview of aortic stenosis diagnosis and treatment. Chapters address such topics as the use of computer tomography in assessing aortic stenosis, role of frozen allografts in aortic valve surgery, transcatheter aortic valve implantation (TAVI), the Ross procedure, and more.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Congenital Heart Defects (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-02-15
    Description: Over the last 50 years, there have been remarkable developments in the diagnosis and treatment of congenital heart defects. This book addresses some of these developments, including the role of echocardiography in improving the prognosis of fetal heart defects, benefits of new echo techniques, cardiac screening of participants in sports, management of premature babies with patent ductus arteriosus, and advantages of stenting the right ventricular outflow tract. It also discusses several types of heart defects, including ventricular septal defect, atrioventricular septal defect, hypoplastic left heart syndrome, and Ebstein’s anomaly of the tricuspid valve. Finally, the book discusses the treatment of congenital aortic valve disease and issues related to managing congenital heart disease in developing countries.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Cardiac Pacing and Monitoring (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Different artificial tools, such as heart-pacing devices, wearable and implantable monitors, engineered heart valves and stents, and many other cardiac devices, are in use in medical practice. Recent developments in the methods of cardiac pacing along with appropriate selection of equipment are the purpose of this book. Implantable heart rate management devices and wearable cardiac monitors are discussed. Indications for using specific types of cardiac pacemakers, cardiac resynchronization therapy devices, and implantable cardioverter defibrillators (ICDs) are of interest and their contraindications are considered. Special attention is paid to using leadless devices. The subcutaneous ICD obviates the need for transvenous leads and leadless pacemakers are entirely implantable into the right ventricle. Finally, applications of user-friendly wearable devices for the detection of atrial arrhythmia are debated.
    Keywords: sudden cardiac death, heart failure, stroke, atrial fibrillation, arrhythmia, cardiac resynchronization therapy ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Advances in the Molecular Understanding of Colorectal Cancer (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: An understanding of the molecular pathogenesis of colorectal cancer by researchers and clinicians is essential to facilitate progress in improving patient outcomes in this common cancer that still carries a poor prognosis if not identified early. This book covers the major areas of importance in the field, incorporating new knowledge that has arisen due to the advancement of molecular techniques and the ability to correlate molecular changes with clinical behaviour of tumours. Each chapter is a summary written by experts, concisely summarising current data as well as highlighting potential areas for advancement. Appreciating the differences between tumours on a molecular level is the key to developing and delivering precision medicine, and nowhere is this more critically required than in the field of colorectal cancer.
    Keywords: epigenetics, biomarker, mass spectrometry, proteomics, dna methylation, personalized medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Interventional Treatment for Structural Heart Disease (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Interventional Treatment for Structural Heart Disease is an excellent resource for healthcare professionals treating patients suffering from severe coronary artery disease and valvular disease. It includes six chapters over two sections covering such topics as percutaneous coronary intervention and transcatheter valve replacement for aortic, mitral, and tricuspid valves.
    Keywords: percutaneous coronary intervention, diabetes mellitus, coronary artery bypass grafting, acute coronary syndrome, tricuspid valve ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Neoplasm (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: Neoplasm refers to an abnormal tissue growth that arises as a consequence of rapid cell proliferation and continues to grow abnormally even after terminating the stimuli that had instigated the change. It lacks partial or complete functional coordination with that of the normal tissues. Neoplasms are classified depending on the degree and type of tissues involved. Carcinogenesis is a multistep process where a plethora of endogenous and exogenous factors turns out genetic and epigenetic modifications, which collectively amend some critical cellular pathways controlling the proliferation, apoptosis, and differentiation. The cells having aberrant modifications are transformed into malignant ones of which the clonal expansion results in the development of cancer. This book provides the reader with a comprehensive overview of various cancer types along with their molecular mechanisms of initiation and progression. It also describes the current knowledge about the state-of-the-art measures being employed in cancer diagnosis and therapeutics. Particular attention is paid to make this book equally useful for students, practitioners, and expert scientists.
    Keywords: cancer, biomarkers, immunotherapy, surgery, chemotherapy, metabolism ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Congenital Heart Disease (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Congenital Heart Disease is a general term for a range of birth defects that affect the normal workings of the heart. It is one of the most common types of birth defect occurring in 1% of live births and affects up to 9 in every 1,000 babies born in the United Kingdom. It was estimated that 34.3 million people had a congenital heart abnormality in 2013. Abnormalities can arise in 3-5% of off spring in cases of de novo family history. Congenital heart disease was responsible for 223,000 deaths in 2010. This short volume details the common birth defects affecting the structure and functioning of the heart concentrating on the genetic basis and epidemiology, as well as risk factors, diagnostic modalities and treatment options.
    Keywords: surgery, percutaneous intervention, cardiopulmonary bypass, interleukin, stenting, indomethacin ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Advanced Concepts in Endocarditis (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Endocarditis is a disease process that involves an infection of the heart, cardiac structures, or implantable cardiac support devices and can be a difficult clinical problem. As patients get older and have more comorbidities, their risks for infection increase. In addition, the growing problem of intravenous substance abuse has led to a considerable increase in these patients developing endocarditis. Advances in medical technology have facilitated diagnosis and management, particularly with greater emphasis on early surgical intervention. Nevertheless, success requires a team approach and individualization of care in the setting of very complex medical, surgical, and ethical problems. The goal of this book is to illustrate some of the evolving challenges and controversies in managing these very complex and often extremely sick patients.
    Keywords: echocardiography, infective endocarditis, risk factors, ethics, addiction, congenital heart disease ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Atherosclerosis (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Atherosclerosis is a subject of enormous contention for cardiologists and in general for all medical doctors. With this publication we have given you a concise "state-of-the-art" look at the world of atheroma. Many other elements could be included and so it is only a brief analysis of "today" (the preventive medicine era) and "tomorrow" (transforming the cure medicine era into the care medicine era) but also remembering "yesterday" (the ex-cathedra medicine era). Let's hope our arteries are free from atherosclerotic events: have a good read!
    Keywords: autophagy, cholesterol, ischemic heart disease, inflammation, dementia, macrophages ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Head and Neck Cancer (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: This book includes useful and recent information to the readers regarding the following topics: Signs and symptoms and etiology and risk factors of head and neck cancer, Epidemiology and the role of microRNAs in nasopharyngeal carcinoma and oral carcinogenesis, History, classifications, and managements of salivary gland cancer, Considerations, classifications, and managements of thyroid gland cancer, Updates in the diagnosis and management of medullary thyroid carcinoma, Interventional techniques used for the relief of head and neck cancer pain, Oral side effects of head and neck irradiation, Health-related quality of life in maxillectomy patients rehabilitated with obturator prostheses
    Keywords: epidemiology, biomarker, chemotherapy, radiotherapy, micrornas, carcinoma ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Protein Kinases (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: For the past two decades, the protein kinase family has been an intense area of research for developing anticancer drugs. Despite tremendous advancements in kinase drug expansion, many kinases are still unexplored. As such, this book includes research and review articles from experts that focus on protein kinase signalling pathways as a molecular drug target. Chapters include illustrations and cover such topics as the mechanism of action and anticancer activity of protein kinase inhibitors on various cancer types. They also discuss new opportunities, challenges, and future perspectives in the field.
    Keywords: toxicity, targeted therapy, drug resistance, clustering, inhibitor, cancer therapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
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    Cyclodextrins (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Cyclodextrins (CDs) have attracted great interest from the research community as well as industries in an array of sectors because of their unique structural features. This book provides a comprehensive overview of CDs, beginning with their historical background. Chapters address such topics as the structure and physiochemical properties of CDs, advancements in the field, and potential applications of these materials in fields such as drug delivery and sensing. This book reveals new frontiers in the CD world and is a useful resource for organic, analytical, and supramolecular chemists as well as scientists engaged in biological and material sciences.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry::PNNP Polymer chemistry
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    Cardiac Diseases (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: This is the latest book in a series of cardiovascular-related texts from IntechOpen Publishing. The present volume considers general aspects of cardiac disease and is divided into three distinct sections covering cardiac risk, cardiorenal pathology, and novel interventional surgical techniques. The chapters offer insight into the current state of the art with respect to the risks of developing cardiovascular diseases, maintenance of patent vascular access in patients with the cardiorenal syndrome, and a plethora of novel interventional technologies all aimed at salvaging damaged tissue and improving prognosis and reducing mortality. This volume of 18 chapters is intended for general medical and biomedical students at both undergraduate and postgraduate level. It also offers insightful updates on recent advances in the understanding of the pathophysiology of cardiac diseases and the new techniques added to the medical armamentarium to improve the outcomes and prevent mortality and would be of interest to those working in academia and healthcare science.
    Keywords: inflammation, cardiovascular disease, stroke, heart disease, acute myocardial infarction, reperfusion injury ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Structural Insufficiency Anomalies in Cardiac Valves (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Heart valves are the basic functional structure of the heart to obtain, sustain, and maintain blood circulations in the body without energy loss, allowing blood regurgitation or obstructing blood flow. There are two basic designs of heart valves: actively protected via subvalvular apparatus (atrioventricular valves) and passively strengthened (ventriculoarterial valves). The embryologic and morphologic development of heart valves is the key stage to continue normofunctional structure and physiological behavior. Fetal anomalies, embryologic defects, or non-development pathologies may damage the structure of heart valves and cause functional deterioration at different grades. In this book, we have focused on specific pathologies, which require special knowledge and treatment modalities.
    Keywords: heart failure, biomechanics, biochemistry, preeclampsia, cardiac resynchronization therapy, aortic stenosis ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Sorption (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: The book presents a comprehensive overview of sorption, which is a multi-parametric separation process. It is extensively used in the removal of various pollutants from the tertiary stage of wastewater treatment, from leachates, etc. It discusses fundamental points of the technique as well as kinetic theories and isotherms. It also examines the synthesis and characterizations of all studied adsorbent materials to find their paths of sorption. Finally, it highlights the importance of having a cost-estimation plan for the synthesis of sorbent materials as well as predictions for their reusability.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNR Physical chemistry::PNRX Surface chemistry and adsorption
    Language: English
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    Cardiac Rhythm Management (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-02-15
    Description: Many methods, techniques, and tools have been developed and successfully applied to stabilize and control heart rate. Modern implantable devices (pacemakers, defibrillators, tools for continuous monitoring and resynchronization therapy) and treatment methods, including minimally invasive surgery (ablation, implantation), have been developed for managing cardiac rhythm and avoiding heart failure. In addition to electrical pacing, ablation is an effective minimally invasive surgical method for reducing and blocking arrhythmic phenomena, both as an independent treatment method or in conjunction with pacing therapy. This book discusses modern cardiac rhythm management methods and devices as well as some important medical aspects of their use.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Endothelial Dysfunction (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations.
    Keywords: inflammation, oxidative stress, biomarkers, pregnancy, atherosclerosis, angiogenesis ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Human Papillomavirus (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-03-31
    Description: This book is a feast of knowledge, yet a balanced diet of healthy foods. There are high values of rich essential nutrients from top-quality medical research. But they are made easily digestible and absorbable, even by health care providers and planners, working in resource-limited settings, in all parts of the world, through social implications and community applications. All the chapters are value-added master pieces. The book would serve both as a scientific reference guide and a practical work manual. The authors, editor, and Intech publishers, together, are pleased to provide the readers a precious blend of scientific excellence and social relevance, for health empowerment, globally. We wish the readers great success, savoring science and sociology together.
    Keywords: cervical cancer, hpv, cancer, epidemiology, vaccine, colorectal cancer ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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    Myocardial Infarction (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Atherosclerotic cardiovascular disease is still the most common cause of death among adults. Its prevalence is increasing in developing countries and despite all advances in both diagnostic tools and treatment modalities, it is still very common in the developed world. Obesity, diabetes mellitus, hypercholesterolemia and overuse of dietary salt play a pivotal role in increased cardiovascular morbidity and mortality worldwide. Current clinical efforts are mainly focused on the diagnosis and treatment of myocardial infarction. In this book, we provide epidemiological data on myocardial infarction and atherosclerotic cardiovascular disease, current diagnostic biochemical tests and management strategies. A specific patient group, children, experiencing myocardial infarction are also addressed. Current advances in the management of myocardial infarction have decreased the morbidity and mortality from atherosclerotic cardiovascular disease and especially myocardial infarction; however, more can be achieved by the prevention of atherosclerotic processes via focusing on the early stages of the disease.
    Keywords: epidemiology, risk factors, coronary artery disease, cardiac arrest, shock, acute myocardial infarction ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Peripheral Arterial Disease (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2023-12-01
    Description: "Peripheral Arterial Disease - A Practical Approach" is an honest effort to provide a clinically relevant approach to the management plan in patients presenting with peripheral vascular symptoms. We have summarized the most pertinent practical aspects of peripheral vascular disease, their clinical implications, diagnostic testing, therapeutic interventions and innovations. We hope this book serves as a reference for basic and advanced peripheral vascular care.
    Keywords: atherosclerosis, extracranial, epigenetics, genetics, stroke, stenting ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Management of Dyslipidemia (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-12-01
    Description: Dyslipidemia is a major risk factor for cardiovascular events, cardiovascular mortality, and all-cause mortality. The earlier in life dyslipidemia is treated, the better the prognosis. The current book is an excellent one on dyslipidemia written by experts on this topic. This book includes 12 chapters including 5 on lipids, 4 on hypercholesterolemia in children, and 3 on the treatment of dyslipidemia. This book should be read by all health care professionals taking care of patients, including pediatricians since atherosclerotic cardiovascular disease begins in childhood.
    Keywords: cardiovascular disease, statins, familial hypercholesterolemia, covid-19, diabetes, atherosclerosis ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
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    Carotenoids (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2024-04-05
    Description: Carotenoids are natural and versatile secondary metabolites, most of them showing colours that vary from yellow to red. They are widespread among living beings where they are involved in many biological roles reporting beneficial actions. To date, more than 750 carotenoids have been described in nature. Humans cannot synthesize carotenoids de novo, thus they are mainly obtained through diet. In fact, carotenoids are consistently found in tissues or biological fluids where they play a beneficial decreasing the risk of developing some diseases.During the last half-century, significant advances in carotenoids research have been made. This book highlights new perspectives and applications of carotenoids including characterization and isolation of new compounds (including rare carotenoids), their production at a mid-large scale (involving new innovative approaches), and uses of carotenoids in different biotechnological fields like food science, biomedicine, and cosmetics.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistry
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    Heart Transplantation (2023)
    IntechOpen | IntechOpen
    Details
    Publication Date: 2023-02-15
    Description: Since the first heart transplantation was performed by Dr. Christiaan Barnard in South Africa in 1967, there has been steady progress in terms of recipient selection, donor selection and management, surgical technique, preoperative management, immunosuppression, mechanical circulatory support during waiting for heart transplantation, especially in the last two decades. This book presents recent information in the field of heart transplantation. It includes thirteen chapters that address such topics as novel immunosuppression therapy and the role of transplant pharmacists, donor management and intervention for primary graft failure, mechanical circulatory, diagnostic modalities for cardiac allograft vasculopathy, surgical techniques, pediatric heart transplantation, and gene therapy. We hope that readers will find this book a useful resource because of its summarization of relevant details and issues that will facilitate the acquisition of emerging new information in each area of heart transplantation.
    Keywords: Clinical & internal medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJD Cardiovascular medicine
    Language: English
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    Infrared Spectroscopy (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Infrared Spectroscopy - Perspectives and Applications is a compendium of contributions from experts in the field of infrared (IR) spectroscopy. This assembly of investigations and reviews provides a comprehensive overview of the fundamentals as well as the groundbreaking applications in the field. Chapters discuss IR spectroscopy applications in the food and biomedicine sectors and for measuring transport through polymer membranes, characterizing lignocellulosic biomasses, detecting adulterants, and characterizing enamel surface advancements. This book is an invaluable resource and reference for students, researchers, and other interested readers.
    Keywords: Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry::PNFS Spectrum analysis, spectrochemistry, mass spectrometry
    Language: English
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    Human Skin Cancer, Potential Biomarkers and Therapeutic Targets (2023)
    IntechOpen | IntechOpen
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    Publication Date: 2024-03-31
    Description: Skin cancers, basal and squamous cell carcinomas, malignant melanomas, and Merkel cell carcinomas, constitute arguably the most common and increasingly prevalent human neoplasms. Here we discuss the epigenetic changes in DNA and chromatin, which are increasingly associated with melanoma. Several chapters focus on the posttranscriptional modification of the proteins at the melanocyte cell surface, their role in tumorigenesis, and their potential as therapeutic targets. Specifically, extracellular modifications of integrins, glycosylation of cell surface proteins, and changes of cadherins are presented. In a very interesting approach, a potential to target the mitochondria of melanoma cells is investigated. In conclusion, this volume presents various aspects of human skin cancers, components of the large worldwide effort to combat and eradicate this growing health concern.
    Keywords: melanoma, glycosylation, epigenetics, metastasis, cytotoxicity, migration ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology
    Language: English
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