ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences  (234)
  • GEOPHYSICS
  • Inorganic Chemistry
  • thema EDItEUR::N History and Archaeology::NH History
  • MDPI - Multidisciplinary Digital Publishing Institute  (290)
  • 2020-2024  (290)
  • 1910-1914
  • 2021  (290)
Collection
Language
Years
  • 2020-2024  (290)
  • 1910-1914
Year
  • 1
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Keywords: QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: Scale up and implementation of new point-of-care (POC) diagnostics is a global health priority to enable the adoption of new evidence-based POC diagnostics and to replicate and extend the reach of POC diagnostics. Global private and public sector agencies have significantly increased their investment in the development of POC diagnostics to meet the unmet needs of patients in resource-limited settings, particularly disease burdened settings with limited access to laboratory infrastructure. However, previous research has demonstrated that the availability of health technologies in these settings does not always guarantee patient-centered outcomes. The applicability, effectiveness and sustainability of diagnostic technologies is affected by the involvement of all stakeholders during planning and implementation, which must be relevant to each specific context and sensitive to local culture. Factors such as infrastructure, resources, values and characteristics of participants can influence the implementation, scalability and sustainability of health interventions such as POC diagnostics. This book, “Implementation and Scale up of Point of Care (POC) Diagnostics in Resource-Limited Settings”, presents literature reviews and primary research studies focusing on the implementation and scale up of POC diagnostics in resource-limited settings.
    Keywords: point-of-care-ultrasound ; ultrasound ; implementation ; point of care ultrasound ; augmented reality ; telemedicine ; spatial accessibility ; blood group ; rhesus type ; point-of-care testing ; maternal healthcare ; Upper East Region ; Ghana ; point-of-care ultrasound ; medical education ; syphilis ; maternal mortality ; interrupted time series ; segmented regression analysis ; point-of-care CD4+ t testing ; qualitative survey ; acceptability ; patients ; healthcare providers ; primary healthcare clinics ; HIV self-testing ; scale-up ; key stakeholder ; quality HIV point-of-care-diagnostics ; nominal group technique ; stakeholder engagement ; self-testing ; novel coronavirus disease-19 ; blockchain ; artificial intelligence ; geographical access ; glucose-6-phosphate dioxygenase deficiency ; antenatal care ; upper east region ; schistosomiasis ; barriers to diagnostics ; access to healthcare ; end-user perspectives ; neglected tropical diseases ; Nigeria ; case management ; electronic health information system ; diagnosis ; treatment ; point-of-care ; low and middle income countries ; point-of-care diagnostics ; healthcare services ; COVID-19 era ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: Neural control of human motor output and how it is modified by alterations in physical activity levels is complex and multidimensional. The use of various experimental designs has vastly increased our knowledge of how the nervous system integrates descending, segmental, and ascending information to produce motor outputs, yet there is still much to learn. A more complete picture of the neurophysiology underlying the control of human motor outputs may prove useful in guiding rehabilitation programs aimed at reducing motor impairments following disease or injury. The purpose of this Special Issue is to collect original articles that explore neural excitability in various states. Studies examining neural excitability on a moment-to-moment basis (acute) or following prolonged periods of exercise or skill training and disuse (chronic) are encouraged. Original research studies using various experimental measures (e.g., transcranial magnetic stimulation, transmastoid electrical stimulation, single motor unit recordings, electroencephalography, and measures of spinal reflexes) in various states (e.g., fatigued, non-fatigued, and resting) during different types of motor outputs (tonic or dynamic) are encouraged. Experimental studies and literature reviews are welcome.
    Keywords: thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Recombinant viruses expressing reporter fluorescent or bioluminescent proteins are an excellent option to evaluate the dynamics of viral infection progression in both cultured cells and/or validated animal models of viral infection. Reporter proteins are valid surrogates for direct detection of infected cells in vitro and in vivo, without the use of secondary methodologies to identify infected cells. By eliminating the need of secondary labeling, tractable replicating-competent, reporter-expressing viruses provide an ideal approach to monitor viral infections in real time, representing a significant advance in the study of the biology of viruses, to evaluate vaccination approaches, and to identify new therapeutics against viral infections using high-throughput screening settings. In this Special Issue “Replication-Competent Reporter-Expressing Viruses” we review replication-competent, reporter-expressing viruses belonging to different families, methods of characterization, and applications to facilitate the study of in vitro and in vivo viral infections. We also seek to discuss disadvantages and limitations associated with these reporter-expressing viruses. Finally, we provide rational future perspectives and additional avenues for the development, characterization, and applications of recombinant, reporter-expressing, competent viruses.
    Keywords: QH301-705.5 ; luminescence ; virus rescue approaches ; fluorescence ; Recombinant viruses ; plasmid-based reverse genetics ; reporter genes ; replicating-competent reporter-expressing viruses ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Several epidemiological studies have demonstrated that oxidative stress is associated with a number of health disorders, including cardiovascular malfunction, certain types of cancer, diabetes mellitus, many other auto-immune diseases, and even ageing. The body possesses multiple mechanisms to counteract oxidative stress, which employ antioxidant compounds that are either naturally generated in situ (endogenous antioxidants) or externally supplied through food (exogenous antioxidants). These antioxidants are able to counteract oxidative stress, thanks to their ability to neutralize excess free radicals and protect the cellular lipids, proteins, and DNA from molecular damage. Exogenous antioxidants from the diet are of increasing interest because of their beneficial role in maintaining good health and in preventing chronic diseases. Indeed, a diet rich in dietary antioxidants, especially from fruits and vegetables, has been correlated with a successful prevention and lower incidence of several degenerative pathologies, including obesity, diabetes, cardiovascular diseases, and cancer. This Special Issue of Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature, examining the role of diets rich in antioxidant compounds in the prevention of chronic diseases and the characteristics of the antioxidants included in such diets.
    Keywords: QH301-705.5 ; antioxidants ; chronic diseases ; dietary supplementation ; human health ; prevention ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/png
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Diet and nutrition are key tools in promoting health and reducing the comorbidities of chronic diseases. There are thousands of biomolecules in fruits, vegetables, wild and medicinal plants, other land and marine organisms, which can exert functional and health-promoting effects through bioactivity beyond nutrition. From the enormous amount of knowledge generated from different natural bioactive ingredients present in foods, we are aiming to bring together experts working in different fields of food, nutrition, and health, in order to work on this Special Issue, with a comprehensive collection of papers to gain insight into the most promising bioactive compounds in different foods, to improve the preservation of bioactivity during the food processing chain, and to provide scientific evidence of the efficacy of key bioactives in foods in preventing disease and improving health and wellbeing.
    Keywords: QH301-705.5 ; TX341-641 ; Health ; Bioactives ; Nutrition and Metabolism ; Nutrients ; Bioavailability ; Food ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: The overall focus, scope, and purpose of this Special Issue on outdoor adventure is to provide the current and anticipated future trends, offer innovative ideas for new programs, support decision making for managers to move plans and intentions into action, inspire pioneering staff training and leadership development, incite policy reviews and revisions, promote resource (re)allocation where needed, and stimulate culture shifts among outdoor leaders and managers. Furthermore, this Special Issue is situated within the existing literature by depicting major trends in the field, exploring organizational issues and successes, identifying gaps between research and practice, and formulating solutions to some of the field’s most pressing challenges. Of particular interest were manuscripts reporting the following: • Adventure education across diverse cultures; • Innovative partnerships for experiential education outdoors; • Land management agencies working with adventure education programs; • Leadership and/or management issues and challenges; • Programming advances, participation trends; • Recruitment and retention of diverse staff, workforce enhancement; • Social groups/identity and outdoor spaces (e.g., people of color and outdoor adventure; women in the outdoors—where have we been, where are we going?; LGBTQ trends and future directions; youth and outdoor adventure); • Socioeconomic factors and solutions; • Technology influences and adventure education; • Working with schools/school districts and being in sync with curriculum needs, supporting transportation challenges, etc.
    Keywords: outdoor adventure education ; social justice ; inclusive praxis ; Outward Bound ; policy ; purposes ; practice ; barriers ; outdoor learning ; outdoor and adventure education ; international perspectives ; comparative ; experiential learning ; transformative learning ; equity ; pedagogy ; whiteness ; gender ; critical theory ; outdoor education ; outdoor skills ; partnership ; outdoor programs ; outdoor education in urban areas ; outdoor recreation ; female empowerment ; single-gender ; adolescent programming ; adolescent girls ; outdoor camp ; girls’ camp ; youth development ; treasure hunt ; mobile learning ; geocaching ; smartphone ; educational app ; Lesvos island ; secondary education students ; undergraduate students ; nature-based programs ; ecological framework ; COVID-19 impact ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JN Education
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 8
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 9
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Keywords: QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 10
    Publication Date: 2024-04-05
    Description: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 11
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
    Keywords: QH301-705.5 ; Q1-390 ; glutamic acid ; n/a ; direct mass spectrometry ; neurodegeneration ; 6-OHDA ; targeted mass spectrometry ; mitochondrial dysfunction ; myo-inositol ; metabolomics ; bile acids ; subacute mild traumatic brain injury ; age-related macular degeneration ; metabolic pathways ; energy metabolism ; midbrain ; Alzheimer’s disease ; biomarkers ; 1H NMR ; Parkinson’s disease dementia ; GC-MS ; pathogenesis ; tricarboxylic acid cycle ; micro-dialysis ; 13C-labeled succinate ; metabolism ; lipidomics ; dementia with Lewy bodies ; fatty acid ; prodromal Parkinson’s disease ; malonate ; cerebral ischemia ; mass spectrometry ; retinal pigment epithelium ; excitotoxicity ; endothelin-1 ; reperfusion ; C. elegans ; Streptomyces venezuelae ; ?-synuclein aggregates ; natural product ; fatty acid metabolism ; imaging mass spectrometry ; LC-MS ; drusen ; cerebral palsy ; plasma ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 12
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
    Keywords: QH301-705.5 ; SF1-1100 ; Q1-390 ; n/a ; muscle texture ; fractal analysis ; fish welfare ; Danio rerio ; motivation ; histopathology ; elevated phosphate concentrations ; sharks ; welfare ; African catfish (Clarias gariepinus) ; feed efficiency ; fighting ability ; aggressive interaction ; social rank ; boldness ; ethology ; fisheries management ; physiological response ; FishEthoBase ; welfare scores ; welfare criteria ; stress ; pain ; stereotypical behaviour ; Scyliorhinus canicula ; animal behavior ; welfare enhancement ; social communication ; nociception ; negative and positive affect ; aggression ; fertilisation success ; risk analysis ; aquaculture ; hematology ; Amyloodinium ocellatum ; framework ; structural complexity ; territorial ; growth ; positive welfare ; social stress ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 13
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The re-use of industrial food residues is essential in the general framework of rational waste handling and recycling, which aims at the minimizing environmental impact of food production and producing functional food ingredients. Agri-food processing waste has long been considered a valuable biomass with a significant polyphenol load and profile. Polyphenols, aside from being powerful antioxidants that confer inherent stability to a variety of foods, may possess versatile bioactivities including anti-inflammatory and chemopreventive properties. The valorization of agri-food waste as a prominent source of polyphenols stems from the enormous amount of food-related material discharged worldwide and the emerging eco-friendly technologies that allow high recovery, recycling, and sustainable use of these materials. This book addresses the concept of recovering natural polyphenolic antioxidants from waste biomass generated by agri-food and related industrial processes and presents state-of-the-art applications with prospect in the food, cosmetic, and pharmaceutical industries.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; valorization ; ultrasound assisted extraction ; microwave assisted extraction ; Box–Behnken design ; HPLC-DAD-q-TOF-MS ; Dioscorea batatas ; green oleo-extraction ; grape marc ; quantitative analysis ; natural antioxidants and flavors ; antioxidant ; infrared-assisted extraction ; anti-ageing ; anthocyanins ; liquid chromatography-mass spectrometry ; Chinese yam ; functional food ; extraction ; olive mill wastewater ; adsorbents ; relative solubility simulation ; HPLC-fluorometric detector (FLD)–MS ; saffron ; antioxidants ; food-grade solvents ; Mango ; zero-waste biorefinery ; response surface methodology ; ophthalmic hydrogel ; olive leaves ; sonotrode ultrasonic-assisted extraction ; vegetable oils and derivatives ; anti-inflammatory ; skin whitening ; phenolics ; Brewers’ spent grains ; proanthocyanidins ; brewer’s spent grain ; anti-inflammatory and antioxidant activity ; antimicrobial activity ; by-products ; antiplatelet activity ; phenanthrenes ; wine lees ; bioactive compounds ; deep eutectic solvents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 14
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Mycotoxins are secondary metabolites produced by molds. Although the primary role of these toxins is thought to be related to the colonisation of the environment by the fungi—mycotoxins are able to kill other micro-organisms (antimicrobial effect) and/or plant cells (mycotoxin-producing fungi being necrophagic)—the exposure of animals and humans to mycotoxins through the consumption of mycotoxin-contaminated food and feeds leads to diseases and death. Among the different mycotoxins described (more than 350 mycotoxins have been identified), deoxynivalenol (DON or vomitoxin) produced by Fusarium species has attracted the most attention due to its prevalence and toxicity. DON is part of a family of mycotoxins called trichothecenes that are small sesquiterpenoids with an epoxide group at positions 12–13 allowing their binding to ribosomes causing the so-called ribosome stress response, characterized by the activation of various protein kinases that lead to alterations in gene expression and cellular toxicity in animals, humans and plants. Here, we compiled very recent findings regarding DON and its derivatives: i) their prevalence in human food; ii) the estimation of the exposure of humans to them using biological markers; iii) their roles during plant–fungi interaction; iv) the alteration caused by them in animals and humans, particularly at low doses that are close to those observed in farm animals and human consumers; v) possible strategies to decrease their presence in food and feeds. Overall, this book will give the reader a clear and global view on this important mycotoxin produced by Fusarium species which is responsible for huge economic loss and health issues.
    Keywords: QH301-705.5 ; cell entry ; deoxynivalenol ; DON derivative ; cell effect ; trichothecene ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 15
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Fire regimes (occurrence, cycle, severity, size, etc.) are key factors in many forest ecosystems, as they are often critical drivers of forest composition, dynamics, and ecosystem processes. Fire regimes vary in space and time according to climatic, physical and biological factors. A better understanding of the interacting factors controlling fire regimes may contribute to improving fire and forest management and their future projection in the context of global change. Knowledge of how fire regimes affect natural landscapes is also used in forestry as a template to manage the forest for wood production. This approach, keeping biodiversity and ecological processes associated with natural fire regimes, may also help in maintaining forest productivity and resilience in the face of climate change. This Special Issue aims to synthesize current understanding of factors affecting fire regime characteristics, to present recent research on fire regimes and their effects on forest ecosystems, and to illustrate how this knowledge could be translated into forest or fire management strategies in the context of global change.
    Keywords: QH301-705.5 ; Fire regime ; Natural disturbances ; Wildfire ; Global change ; Forest management ; Forest ecosystems ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 16
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Concerns have been raised with respect to the state of high-altitude and high-latitude treelines, as they are anticipated to undergo considerable modifications due to global changes, and especially due to climate warming. As high-elevation treelines are temperature-limited vegetation boundaries, they are considered to be sensitive to climate warming. As a consequence, in this future, warmer environment, an upward migration of treelines is expected because low air and root-zone temperatures constrain their regeneration and growth. Despite the ubiquity of climate warming, treeline advancement is not a worldwide phenomenon: some treelines have been advancing rapidly, others have responded sluggishly or have remained stable. This variation in responses is attributed to the potential interaction of a continuum of site-related factors that may lead to the occurrence of locally conditioned temperature patterns. Competition amongst species and below-ground resources have been suggested as additional factors explaining the variability in the movement of treelines. This Special Issue (book) is dedicated to the discussion of treeline responses to changing environmental conditions in different areas around the globe.
    Keywords: QH301-705.5 ; QK1-989 ; Q1-390 ; n/a ; tree seedling recruitment ; shrubline ; light quality ; higher altitude ; precipitation ; experimental rain exclusion ; Pinus cembra ; Changbai Mountain ; treeline dynamics ; fungal ecology ; thermal continentality ; tree regeneration ; elevational transect ; monitoring ; conifer shrub ; plant water availability ; permafrost ; foehn winds ; treeline ; Holocene ; nitrogen cycling ; carotenoids ; timberline ; 15N natural abundance ; spectrometer ; basal area increment ; palynology ; xylem embolism ; diversity ; elevational treeline ; European Alps ; temperature ; tree line ; winter stress ; photosynthetic pigments ; Pinus sibirica ; westerly winds ; relative air humidity ; ecosystem manipulation ; Larix decidua ; microsite ; polar treeline ; Central Austrian Alps ; Switzerland ; multi-stemmed growth form ; conifers ; forest edge ; history of treeline research ; soil drought ; dendroclimatology ; knowledge engineering ; Rocky Mountains ; apical control ; cloud ; postglacial ; alpine timberline ; space-for-time substitution ; climate change ; expert elicitation ; shoot elongation ; pit aspiration ; climate warming ; climate zone ; alpine treeline ; refilling ; Abies sibirica ; growth trend ; western Montana ; light quantity ; Picea abies ; Mediterranean climate ; forest climatology ; altitude ; environmental stress ; sub-Antarctic ; Erman’s birch ; photoinhibition ; tocopherol ; elevational gradients ; NDVI ; long-term trends ; sap flow ; peat ; tree seedlings ; Southern Ocean ; chlorophyll ; non-structural carbohydrates (NSCs) ; drought ; upward advance ; remote sensing data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 17
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Forests cover 30% of the Earth’s land area, or nearly four billion hectares. Enhancing the benefits and ecosystem services of forests has been increasingly recognized as an essential part of nature-based solutions for solving many emerging global environmental problems today. A core science supporting forest management is understanding the interactions of forests, water, and people. These interactions have become increasingly complex under climate change and its associated impacts, such as the increases in the intensity and frequency of drought and floods, increasing population and deforestation, and a rise in global demands for multiple ecosystem services including clean water supply and carbon sequestration. Forest watershed managers have recognized that water management is an essential component of forest management. Global environmental change is posing more challenges for managing forests and water toward sustainable development. New science on forest and water is critically needed across the globe. The International Forests and Water Conference 2018, Valdivia, Chile (http://forestsandwater2018.cl/), a joint effort of the 5th IUFRO International Conference on Forests and Water in a Changing Environment and the Second Latin American Conference on Forests and Water provided a unique forum to examine forest and water issues in Latin America under a global context. This book represents a collection of some of the peer-reviewed papers presented at the conference that were published in a Special Issue of Forests.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; social capital ; Cambodia ; forest and water policy ; land use and land cover change ; shrubland ; “Forests to Faucets” ; precipitation gradient ; forest ecosystem management ; afforestation ; connectivity ; land use change ; forest operations ; Chile ; catchment management ; forest plantation ; climate change ; compound wildfire-water risk ; native forest ; hydrology ; wetland ; streamside native buffer ; sustainability ; participatory monitoring ; hydrological modeling ; timber harvesting ; water quality ; native forests ; source water protection ; global change ; forest hydrology ; community drinking-water ; SDGs ; drinking-water security ; Oregon ; forest ; aquatic-riparian ecosystems ; NDC ; heat: moisture index ; watershed management ; load ; Rhyacotriton ; ecohydrology ; nutrient concentrations ; multi-criteria analysis ; Loess Plateau ; dissolved organic matter ; US Pacific Northwest ; soil moisture ; agricultural lands ; water management ; water provision ; water supply ; forests ; post-fire hydrology ; grassland ; forest plantations ; restoration strategy ; riparian buffer zones ; Mekong ; riparian vegetation ; density management harvest ; SWAT model ; forest watersheds ; water governance ; Nenjiang River ; forestry ; ecosystem services ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 18
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.
    Keywords: QH301-705.5 ; Q1-390 ; thermodynamic modeling ; molecular dynamics simulation ; poorly soluble drugs ; amorphous solid dispersions ; dissolution enhancement ; crystallization tendency ; continuous processing ; stability ; milling ; granulation ; thermal analysis ; amorphous ; ball milling ; pharmaceutical glass ; dissolution ; rebamipide ; poloxamer ; classification ; polyelectrolytes ; amorphisation ; self-assembly ; dissolution rate ; miscibility ; bioavailability ; solubility ; evaporation ; mesoporous ; polyelectrolyte excipient matrix ; polymer ; bicaludamide ; phase diagram ; Weibull dissolution model ; spectroscopic techniques ; anticancer drugs ; manufacturing methods ; nucleation ; molecular complex ; nanoaggregates ; enrofloxacin ; accelerated stability test ; solubility enhancement ; amorphous solid dispersion ; tadalafil ; process development ; amorphous polymeric salt ; Wood’s apparatus ; hot melt extrusion ; solid dispersions ; intrinsic dissolution rate ; solid dispersion ; interaction ; crystallization ; spray drying ; characterization ; ciprofloxacin ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 19
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Rivers have been intensively degraded due to increasing anthropogenic impacts from a growing population in a continuously developing world. Accordingly, most rivers suffer from pressures as a result of increasing dam and weir construction, habitat degradation, flow regulation, water pollution/abstraction, and the spread of invasive species. Science-based knowledge regarding solutions to counteract the effects of river degradation, and melding principles of aquatic ecology and engineering hydraulics, is thus urgently needed to guide present and future river restoration actions. This Special Issue gathers a coherent set of studies from different geographic contexts, on fundamental and applied research regarding the integration of ecohydraulics in river restoration, ranging from field studies to laboratory experiments that can be applied to real-world challenges. It contains 13 original papers covering ecohydraulic issues such as river restoration technologies, sustainable hydropower, fish passage designs and operational criteria, and habitat modeling. All papers were reviewed by international experts in ecology, hydraulics, aquatic biology, engineering, geomorphology, and hydrology. The papers herein well represent the wide applicability of ecohydraulics in river restoration and serve as a basis to improve current knowledge and management and to reduce arguments between different interests and opinions.
    Keywords: QH301-705.5 ; Q1-390 ; Fish passage and migration ; Prioritization of river connectivity for sustainable fisheries ; Sustainable hydropower ; Spawning grounds ; Invasive species management ; Environmental flows ; Habitat modeling ; Dam/weir retrofitting and removal ; Riparian and aquatic vegetation dynamics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 20
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level.
    Keywords: QH301-705.5 ; genome stability ; Trisomies ; microtubule dynamics ; Checkpoints ; Inheritance ; Cell division ; centrosome ; Down Syndrome ; Cell motility ; Cell regulation ; chromosome segregation ; Microtubules ; Cell cycle ; kinetochore ; Cytoskeleton ; Cell reproduction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 21
    Publication Date: 2024-04-05
    Description: Ranaviruses and other viruses within the family Iridoviridae, infect a wide range of ecologically and commercially important ectothermic vertebrates, i.e., bony fish, amphibians, and reptiles, and invertebrates, including agricultural and medical pests and cultured shrimp and crayfish, and are responsible for considerable morbidity and mortality. Understanding the impact of these various agents on diverse host species requires the combined efforts of ecologists, veterinarians, pathologists, comparative immunologists and molecular virologists. Unfortunately, investigators involved in these studies often work in discipline-specific silos that preclude interaction with others whose insights and approaches are required to comprehensively address problems related to ranavirus/iridovirus disease. Our intent here is to breakdown these silos and provide a forum where diverse researchers with a common interest in ranavirus/iridovirus biology can profitably interact. As a colleague once quipped, “Three people make a genius.” We are hoping to do something along those lines by presenting a collection of research articles dealing with issues of anti-viral immunity, identification of a potentially novel viral genus exemplified by erythrocytic necrosis virus, viral inhibition of innate immunity, identification of novel hosts for lymphocystivirus and invertebrate iridoviruses, and modelling studies of ranavirus transmission. Collectively these and others will exemplify the breadth of ongoing studies focused on this virus family.
    Keywords: QH301-705.5 ; Q1-390 ; risk assessment ; n/a ; CQIV ; mathematical models ; amphibian ; iridovirus ; ISDL ; Exopalaemon carinicauda ; viral load ; virus isolation ; European chub ; outbreak ; Unconventional T cell ; early detection ; susceptible species ; viral immune evasion ; DNA virus ; Rana grylio virus ; antibody ; intracellular localization ; Rana grylio virus (RGV) ; British Columbia ; Iridoviridae ; Andrias davidianus ranavirus ; viral infection ; susceptible-infected (SI) models ; yeast two-hybrid (Y2H) ; prevalence ; host-pathogen interactions ; Pacific herring ; Procambarus clarkii ; Bayesian inference ; eDNA ; amphibians ; Artemia spp. ; ranavirosis ; cross-species transmission ; FV3 ; SHIV ; Gryllus bimaculatus ; Pacific salmon ; NF-?B ; cricket ; IIV-6 ; virus binding ; erythrocytic necrosis virus (ENV) ; envelope protein ; iridovirus core proteins ; emerging infection ; host ; Ranavirus ; white head ; Rana temporaria ; Imd ; biosecurity ; antiviral immunity ; Decapodiridovirus ; endemic disease ; Macrobrachium rosenbergii ; co-immunoprecipitation (Co-IP) ; Common frog ; aquatic animals ; virus surveillance ; immunomodulators ; frog virus 3 ; ELISA ; DIV1 ; megalocytivirus ; Lymphocystis disease virus ; bearded dragon ; susceptibility ; protein interaction ; Pogona vitticeps ; viral erythrocytic necrosis (VEN) ; histopathology ; epidemiology ; native-fish conservation ; viral transmission ; Sparus aurata ; immunohistochemistry ; lizard ; disease dynamics ; immunofluorescence ; transmission modelling ; Macrobrachium nipponense ; interferon ; nonclassical MHC ; heparan sulfate ; ranavirus ; Mexico ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 22
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: This book provides a first-of-its-kind review and analysis of benefit sharing frameworks between extractive industries and Indigenous and local communities in different parts of the Arctic. The authors describe a wealth of case studies in order to examine predominant practices, policies, arrangements, mechanisms and impact assessment methodologies. They also discuss possible ways to improve and advance existing benefit sharing regimes, in order to attain fair and equitable benefit sharing and support sustainable development. Among the topics covered in the book are corporate social responsibility and social license to operate, principles and methodologies of determining compensation, legal and informal frameworks of benefit sharing, community response to extractive activities, and global-to-local linkages that shape benefit sharing processes. The book will be of interest to academics, industry experts, legal specialists, policymakers, community members concerned with industrial activities, and anyone interested in sustainable development in the Arctic.
    Keywords: thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 23
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Afforestation/reforestation (or forestation) has been implemented worldwide as an effective measure towards sustainable ecosystem services and addresses global environmental problems such as climate change. The conversion of grasslands, croplands, shrublands, or bare lands to forests can dramatically alter forest water, energy, and carbon cycles and, thus, ecosystem services (e.g., carbon sequestration, soil erosion control, and water quality improvement). Large-scale afforestation/reforestation is typically driven by policies and, in turn, can also have substantial socioeconomic impacts. To enable success, forestation endeavors require novel approaches that involve a series of complex processes and interdisciplinary sciences. For example, exotic or fast-growing tree species are often used to improve soil conditions of degraded lands or maximize productivity, and it often takes a long time to understand and quantify the consequences of such practices at watershed or regional scales. Maintaining the sustainability of man-made forests is becoming increasingly challenging under a changing environment and disturbance regime changes such as wildland fires, urbanization, drought, air pollution, climate change, and socioeconomic change. Therefore, this Special Issue focuses on case studies of the drivers, dynamics, and impacts of afforestation/reforestation at regional, national, or global scales. These new studies provide an update on the scientific advances related to forestation. This information is urgently needed by land managers and policy makers to better manage forest resources in today’s rapidly changing environments.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; simulation modeling ; shear strength ; stand structure ; vegetation restoration ; surface runoff ; soil and water conservation function ; soil enzymes ; riverbank ; evapotranspiration ; human activity ; afforestation ; Artemisia ordosica ; forest cover ; precipitation variation ; soil bioengineering ; base flow ; Poyang Lake Basin ; in situ calibration ; quantification ; chlorophyll fluorescence ; photoprotection ; remote sensing ; root distribution ; ecosystem model ; CASA ; afforestation ecosystem ; phenophase ; vegetation cover change ; soil characteristics ; Robinia pseudoacacia L. and Pinus tabulaeformis Carr. mixed plantations ; composted pine bark ; water-energy balance ; sediment load ; soil respiration ; energy partitioning ; soil microbial biomass ; transpiration ; net primary productivity ; spatio-temporal scales ; seedling quality ; peat moss ; fresh pine sawdust ; understory plants ; ring-porous trees ; different climatic conditions ; dye tests ; structural equation model ; Loess Plateau ; evapotranspiration (ET) ; Pinus engelmannii Carr. ; empirical statistics ; heat dissipation probes ; MODIS ; slope change ratio of cumulative quantities (SCRCQ) ; soil water balance ; LAI ; climate fluctuation ; BTOPMC model ; living brush mattress ; vegetation greening ; streamflow ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 24
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: The use of social media in public health education/promotion has been increasing due, in part, to its ability to remove physical access and geographical barriers for users. Specifically, social media provides an outlet to increase and promote translational health communication strategies and the effective dissemination of health information and data in ways that allow users to not only utilize, but also to create and share pertinent health information. Although social media applications in public health and health promotion have yielded success in terms of generating support structures and networks for effective health behavior change, there are challenges and complications associated with use of social media that also need to be addressed (e.g., managing misinformation, ensuring compliance with privacy protection regulations). This Special Issue aims to explore social media as a translational health promotion tool by bridging principles of health education and health communication. Broadly, this Special Issue is seeking original submissions that examine: (1) the method with which social media users access, negotiate, and create health information that is both actionable and impactful for diverse audiences; (2) strategies for overcoming challenges to using social media in health promotion; and (3) best practices for designing, implementing, and/or evaluating social media campaigns and forums in public health. Special interest will be given to innovative submissions that expand and build upon traditional health education approaches with health communication theories and models. Other manuscript types of interest include relevant position papers, brief reports, and commentaries.
    Keywords: social media-based health management systems ; theory of planned behavior ; openness to new experience ; sustained health engagement ; physical literacy ; activity ; social media ; online resource ; Internet ; HONcode ; YouTube ; COPD ; Facebook ; online community ; self-management ; social support ; healthy consumption ; purchase intention ; trust ; emotional support ; expectation confirmation ; privacy concern ; consumer health informatics ; natural language processing (NLP) ; online support groups ; autism ; micro-video ; Provincial Health Committee ; healthcare ; Tik Tok ; China ; online social support ; social identity ; communication theory of identity ; rural health ; chronic obstructive pulmonary disease ; excessive drinking ; Twitter ; natural language processing ; American Communities Project ; health education ; health promotion ; ethics ; wearable technology ; drive for thinness ; health-oriented websites ; neuroticism ; web content internalization ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 25
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually partitioned into three distinct regions, known as classes I, II, and III, which, to varying extents, can be found conserved in nonmammalian jawed vertebrates, such as bony fish, amphibians, and bird lineages. The MHC gene region is characterized particularly by the expression of class I and class II glycoproteins that bind peptides derived from intracellular or extracellular antigens to circulating T-cells. While this expressed antigenic specificity remains the predominant interest with respect to MHC function and polymorphism in a population, a broader concept has emerged that examines the MHC as a multifunctional polymorphic controller that facilitates and regulates genome diversity with a much greater array of functions and effects than just MHC-restricted antigen recognition. This volume of 19 reprints presented by various experts and collected from the Special Issue of Cells on “MHC in Health and Disease” covers a broad range of topics on the genomic diversity of the MHC regulatory system in various vertebrate species, including MHC class I, II, and III genes; innate and adaptive immunity; neurology; transplantation; haplotypes; infectious and autoimmune diseases; fecundity; conservation; allelic lineages; and evolution. Taken together, these articles demonstrate the immense complexity and diversity of the MHC structure and function within and between different vertebrate species.
    Keywords: QH301-705.5 ; Q1-390 ; HCP5 ; n/a ; camels ; MHC ; STK19 ; major histocompatibility complex ; human papillomavirus (HPV) ; T-cell receptor ; T1DGC ; bottleneck ; micro-mini-pigs ; life history ; computational analysis ; hepatocellular carcinoma ; phase ; Bactrian camel ; NSDK ; melanoma ; antigen ; autoimmune disease ; RD ; selection ; disease resistance ; autoimmunity ; ancestral haplotype ; Ski complex ; DXO ; high-throughput sequencing ; conservation genetics ; SVA ; lncRNA ; ankylosing spondylitis ; MHC genes ; viral peptides ; competing endogenous RNA (ceRNA) ; astrogliosis ; birds ; long-fragment super haplotype ; SNP ; RLR ; HLA polymorphism ; 5??3? RNA decay ; expression ; 3??5? mRNA turnover ; orthology ; long-read sequencing ; disease association ; dromedary ; polyomavirus ; MHC-II-associated sperm-egg recognition ; experimental medicine ; single nucleotide polymorphism (SNP) ; fish ; SKIV2L ; production trait ; molecular dynamics simulation ; Macaca fascicularis ; human endogenous retrovirus (HERV) ; concerted evolution ; polymorphism ; Old World camels ; MHC polymorphism ; protocol ; nonclassical ; gene duplication ; microglial reaction ; human leukocyte antigen-E ; SKI2W ; quantitative trait loci (QTL) studies ; antiviral immunity ; human immunodeficiency virus (HIV) ; founder effect ; giant panda ; domain movements ; BK virus ; promoter-proximal transcriptional pause ; type 1 diabetes (T1D) ; RP1 ; miR1236 ; KIR ; synaptic covering ; swine leukocyte antigen ; cynomolgus macaque ; HLA ; kidney transplantation ; ?2m knockout mice ; DOM3Z ; interferon ? ; ethnic populations in China ; ecology ; KIR–HLA pairs ; exosomes ; major histocompatibility complex (MHC) ; MHC-I-based mother-fetus recognition ; RNA quality control ; autoimmune diseases ; NELF-E ; haplotype ; genetic drift ; evolution ; nonhuman primate models ; HLA-B27 ; PNS/CNS interface ; risk genes ; pedigree ; MHC-I- and MHC-II-dependent inter-individual recognition ; regulation ; crested ibis ; reproductive performance ; nephropathy ; cancer ; nuclear kinase ; trichohepatoenteric syndrome ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 26
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; biorefinery ; polyphenols ; dynamic simulation ; Fucus distichus subsp. evanescens ; seaweeds ; phytochemicals ; Bifurcaria bifurcata ; Fucus vesiculosus ; kidney ; complex polysaccharides ; identification ; secondary metabolites ; phlorotannin ; cholinesterases ; eckol ; skin aging ; clinical trials ; dieckol ; fucoxanthin ; age-related macular degeneration ; photo-protection ; phytol ; Alzheimer’s disease ; fucosterol ; bone health ; nutraceutical ; papillomavirus ; red seaweed ; extraction ; osteoporosis ; fucoidan ; marine algae ; chemo-preventive agent ; ischemia-reperfusion injury ; hyperpigmentation ; bone metabolism ; bioactives ; macroalgae ; beta-secretase ; laurinterol ; prebiotics ; dietary fibre ; NMR spectroscopy ; health effects ; bromophenols ; beta-amyloid aggregation ; kahalalide F ; Padina pavonica ; carotenoids ; insulin glycation ; skincare ; mushroom tyrosinase ; polyunsaturated fatty acids ; fatty acid ; in vivo studies ; apoptosis ; algae ; biological activities ; Symphyocladia latiuscula ; Fucus serratus ; mass spectrometry ; Laminaria digitata ; high-speed counter-current chromatography ; isolation and purification ; K14HPV16 ; amyloid-? aggregation ; VEGF ; melanin ; Laurencia ; seaweed ; organotypic culture ; Saccharina latissima ; ex vivo ; genotoxicity assay ; gut microbiota ; phlorotannins ; eckmaxol ; high value applications ; Ecklonia maxima ; B16F10 ; neuroprotection ; linear diterpenes ; antitumoral ; Ecklonia cava ; cancer ; breast cancer explants ; osteosarcoma ; oxidative stress ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 27
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Carboxylic acids are truly central compounds in cellular metabolism. Carbon dioxide is captured from the atmosphere through formation of carboxylic groups and is also released, in part, by decarboxylation reactions. The reactivity of the carboxylic group with amino- or hydroxyl-groups enables the formation of peptide and ester bonds. The functionality of the carboxylic group is also of huge importance in our industrial world for a wide range of applications. The loosely bound hydrogen provides weak acid functionality, much desired for food industry applications in preservatives and flavour compounds. Citric acid is one of our oldest industrial fermentation products. The presence of two carboxylic groups, or a combination of one carboxylic group and another functional group, make the compounds interesting building blocks for polymer production. A number of carboxylic acids, including, e.g., lactic, succinic, 3-hydroxypropionic and itaconic acids, have been identified and recognized as suitable platform chemicals for a foreseen growing carbohydrate based economy. Economic margins are, however, tight when competing with petroleum based production, and production strains, fermentation technology and—not least—downstream processing, all need to be improved to enable viable commercial production. This Special issue will cover current developments within this exciting field. Topics will include: Fermentation physiology of natural carboxylic acid producers; screening and isolation of novel producers; metabolic engineering for improving intrinsic carboxylic acid production; metabolic engineering for expanding product range to non-endogenous carboxylic acids; production from lignocellulosic derived sugars or by-product streams; downstream processing for recovery of carboxylic acids; bioprocess design—including continuous processes and integration. All production organisms—fungi, yeasts, bacteria—are welcome.
    Keywords: QH301-705.5 ; bioprocess design ; downstream processing ; metabolic engineering ; strain evolution ; fermentation physiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 28
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Beer is a beverage with more than 8000 years of history, and the process of brewing has not changed much over the centuries. However, important technical advances have allowed us to produce beer in a more sophisticated and efficient way. The proliferation of specialty hop varieties has been behind the popularity of craft beers seen in the past few years around the world. Craft brewers interpret historic beer with unique styles. Craft beers are undergoing an unprecedented period of growth, and more than 150 beer styles are currently recognized. This Special Issue, Brewing and Craft Beer, comprises nine different works by researchers from five continents (North America, South America, Europe, Africa, and Oceania). This Special Issue reflects thus a broad perspective on the most important questions that concern the researchers in different parts of the world.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; polyphenols ; n/a ; nutrient ; audible sound ; wet milling ; brewing technology ; robotics ; fast-screening ; lactose ; image analysis ; bottle refermentation ; beer aging ; sensory attributes ; brewing ; automation ; bitterness ; stout beer ; beer ; craft beer ; foamability ; Safrari ; adjuncts ; fermentation rate ; barley milling ; preference ; germ ; beer wort ; machine learning ; carbonation ; quality ; FAN ; granulometry ; sensory evaluation ; coffee ; beer acceptability ; computer vision ; fermentation ; economic contribution analysis ; short-chain fatty acids ; local value chain ; AEDA ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 29
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: Higher education has been considered both an ‘engine’ for innovation and a ‘catalyst’ for sustainability development; the integration of both the innovation engine and sustainability catalyst roles are discussed in a recently published Special Issue on the theme of Higher Education in Innovation Ecosystems in the journal Sustainability. Based on 16 articles contributing to the Special Issue from various perspectives, the Special Issue editors have developed an overarching framework about the relationships between higher education and innovation ecosystems. In the framework, we re-define the concept of innovation ecosystem and identify emerging roles of universities in developing sustainable innovation ecosystems. Re-conceptualization of innovation ecosystems In the editorial of the Special Issue, innovation ecosystem is defined as: co-innovation networks in which actors from organizations concerned with the functions of knowledge production, wealth creation, and norm control interact with each other in forming co-evolution and interdependent relations (both direct or indirect) in cross-geographical contexts and through which new ideas and approaches from various internal and external sources are integrated into a platform to generate shared values for the sustainable transformation of society. Compared with most commonly cited definitions of innovation ecosystem, our definition highlights three new aspects of interactions in co-innovation networks: cross-sectoral, transnational, and indirect, drawing insights from the literature including innovation, geography, and biology studies. The roles of universities in innovation ecosystems The emerging roles of universities in innovation ecosystems are as follows: (1) The role of universities is changing from being a central player in technology transfer to being an anchor in knowledge exchange; (2) universities are assuming a new role in trust-building between actors in innovation ecosystems; and (3) universities are not merely an entrepreneurial universities but are also institutional entrepreneur in the innovation ecosystem. The three emerging roles all indicate that universities are becoming the catalysts for sustainable development in innovation ecosystems. Knowledge exchange is crucial for sustainability; trust is the foundation of the sustainable networks; social entrepreneurship is indispensable for sustainable social change. Evidence in wider contexts A total of 44 authors from 10 countries contributed to the discussions on the changing roles of higher education in innovation ecosystems from varying perspectives. They also report transformations within higher education and universities’ responses to both external and internal transformations. When addressing these issues, the studies provide both theoretical and methodological contributions to the research on higher education in innovation ecosystems. The 16 articles can be generally placed into four categories: (1) new demands for universities arising from the transformation in society toward innovation ecosystems, (2) transformations within higher education responding to emerging societal demands, (3) dynamics of the interaction of university with other innovation actors in a transnational context, and (4) academic and student mobility for higher education innovation. Calling for a new research agenda While societal changes demand broader roles of universities, they also call for and leads to substantial changes within the internal fabric of the university. The innovations in both society and the universities necessitate a renewed understanding of higher education in society, which has become a new research agenda in studies on innovation in higher education. We hope our Special Issue will inspire and encourage more scholars to join the research field.
    Keywords: transnational industry cooperation ; transnational university cooperation ; transnational innovation ecosystem ; EU–China ; science, technology and innovation cooperation ; transdisciplinary approach ; artificial intelligence ; machine learning ; Higher Education ; University ; Entrepreneurial competences ; Employability ; Theory of Planned Behaviour (TPB) ; Open Innovation ; business creation ; technology transfer ; innovation ; innovation ecosystem ; entrepreneurship education ; science and technology ; sustainability ; higher education ; educational innovation ; Mexico ; academic mobility ; knowledge transfer ; higher education innovation ; institutional environment ; postgraduate education ; education level ; discipline background ; graduation institution ; R&amp ; D investment ; triple helix ; synergy mechanism ; national system of innovation ; China ; Belt and Road Initiative ; developmental model of intercultural sensitivity ; general model of instructional communication ; instructional beliefs model ; intercultural communication competence model ; green GDP ; environment ; sustainable development ; global innovation systems ; Chinese research university ; faculty income ; academic labor market ; ordinary labor market ; joint R&amp ; D institute ; institutional logics ; China’s innovation system ; China’s transnational Triple Helix linkages ; problem-solving ; critical reflection ; knowledge integration ; social learning ; systemic thinking ; entrepreneurial university ; entrepreneurship ; influencing factors ; sustainable universities ; corporate sustainability ; tensions ; integrative framework ; Finnish universities ; higher education system ; social entrepreneurship ; entrepreneurial universities ; business model innovation ; socialist economies ; Cuba ; knowledge brokers ; knowledge intensive policies ; smart specialisation ; innovation ecosystems ; global talent ; social integration ; economic integration ; Chinese student ; Finland ; university ; third mission ; knowledge-based society ; global innovation networks ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JN Education
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 30
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron–sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; regeneration ; posttranslational modification ; H2O2 ; chilling stress ; thioredoxin reductase ; X-ray crystallography ; photosynthesis ; Chlamydomonas reinhardtii ; protein ; monodehydroascorbate reductase ; methionine sulfoxide ; cysteine reactivity ; symbiosis ; plant ; MALDI-TOF mass spectrometry ; thioredoxins ; redox homeostasis ; methionine sulfoxide reductases ; redox ; redox signalling ; chloroplast ; protein-protein recognition ; cyanobacteria ; specificity ; wheat ; methanoarchaea ; stress ; redox regulation ; dough rheology ; methionine sulfoxide reductase ; electrostatic surface ; Calvin cycle ; ALAD ; metazoan ; Arabidopsis thaliana ; baking ; cold temperature ; macromolecular crystallography ; protein oxidation ; function ; methionine oxidation ; development ; iron–sulfur cluster ; tetrapyrrole biosynthesis ; legume plant ; glutathionylation ; Calvin-Benson cycle ; adult stem cells ; carbon fixation ; plastidial ; methionine ; redox active site ; ROS ; water stress ; NADPH ; repair ; physiological function ; signaling ; thioredoxin ; antioxidants ; glutathione ; glutaredoxin ; flavin ; Isocitrate dehydrogenase ; thiol redox network ; ageing ; disulfide ; mitochondria ; chlorophyll ; proteomic ; cysteine alkylation ; ferredoxin-thioredoxin reductase ; SAXS ; regulation ; oxidized protein repair ; ascorbate ; redox control ; nitrosylation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 31
    Publication Date: 2024-04-05
    Description: Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; high-fat high-carbohydrate diet ; toxicity ; oxysterol ; n/a ; squalene cyclase ; sterol content ; sterolomics ; Polystichum ; Smith-Lemli-Opitz syndrome ; antifungals ; alkaloid ; cycloartenol synthase ; degeneration ; phytosterol ; Rhizopus arrhizus ; fibroblasts ; pod-blast ; fern ; cholesterol ; cytotoxic activity ; N-methylpiperidine. reductive deamination ; genetic disease ; isoprenoid ; steroid ; atherosclerosis ; granatane ; antioxidant ; wound healing ; development ; enzyme-assisted derivatization ; maturity ; terpene ; keratinocytes ; C4-demethylation complex (C4DMC) ; ?-sitosterol ; mesocarp ; sterol biosynthesis ; mechanism-based inactivators ; Mucorales ; gas chromatography-mass spectrometry (GC-MS) ; Girard reagent ; ROS ; sterol pattern ; N-methylcadaverine ; ?-tocopherol ; electrospray ionization-mass spectrometry ; human African trypanosomiasis ; HUVECs ; lipidomics ; campesterol ; triterpene ; oxyphytosterol ; leishmania ; Chagas disease ; LOX-1 ; sterol C24-methyltransferase ; antifungal effectivity ; ergosterol biosynthesis ; hormone ; glucose homeostasis ; retina ; solanaceae ; cholestanoic acid ; algal sterols ; cell migration ; withanolides ; insulin resistance ; Zingiber officinale ; posaconazole ; synthesis ; pre-diabetes ; pharmacognosy ; sterol ; 4-methylsterol ; oleanolic acid ; antiparasitic drugs ; lupeol ; oilseed ; aurelianolides ; divalent metal co-factor ligation ; bile alcohol ; phytosterols ; azoles ; infectious disease ; gingerols ; UV-radiation ; oil bodies ; ZnO ; sterol 14?-demethylase ; stigmasterol ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 32
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: In 2011, carbohydrates provided 63% of the dietary energy intake to the world’s population. Historically, carbohydrate-rich diets have been associated with good health and longevity but there has been a move away from traditional carbohydrate-rich diets, with refined carbohydrate taking much criticism for contributing to non-communicable disease. The aim of this Special Issue is to discuss the appropriate use of environmentally sustainable carbohydrate-rich foods in the modern diet in developing and developed countries in the context of prevention and treatment of non-communicable disease.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; satiety ; preload ; carbohydrate ; observational study ; body weight ; chronic disease risk ; postprandial ; isomaltulose ; qualitative ; glycaemic glucose equivalents ; mixed meal ; glycaemia ; obesity ; kiwifruit ; knowledge ; carbohydrates ; sugars ; timing ; sucrose ; CVD ; nutrition ; glycemia ; prebiotics ; intestinal biota ; glycemic response ; fibre ; T2DM ; low-carbohydrate diet ; ethnicity ; rice consumption ; activity ; fruit ; exercise ; discussion groups ; potato ; resistant starch ; pasta ; type 2 diabetes mellitus ; glycemic index ; vitamin C ; carbohydrate exchanges ; fructose ; glycemic load ; Japanese diet ; rice ; type 2 diabetes ; glycaemic response ; dietary pattern ; insulinaemia ; diabetes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 33
    Publication Date: 2024-04-05
    Description: Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of “selfishness”, based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these “silent” chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems.
    Keywords: QH301-705.5 ; Q1-390 ; parent-of-origin effects ; fluorescent in situ hybridization ; coverage ratio analysis ; n/a ; ribosomal DNA ; reactivation ; cytogenetics ; epigenetics ; heterochromatin ; interphase nucleus ; whole genome resequencing ; transmission ; grasshoppers ; genome instability ; dot-like (micro) Bs ; ?s ; B chromosome ; supernumerary elements ; transcription of heterochromatin ; maternal X chromosome ; supernumerary chromosome ; population analysis ; supernumerary ; repeat clusters ; extra chromosomes ; genes ; tandem repeats ; B morphotypes ; repetitive DNA ; repetitive elements ; DNA copy number variation ; chromosome polymorphism ; satellite DNA ; mammals ; maize B chromosome ; additional chromosomes ; inactivation ; drive ; B chromosomes ; FISH (fluorescence in situ hybridisation) ; organelle DNA ; Orthoptera ; origin ; supernumerary chromosomes ; karyotype evolution ; GISH (genomic in situ hybridisation) ; DNA composition ; de novo centromere formation ; genomics ; paternal X chromosome ; euchromatin degradation ; supernumerary chromosomal segments (SCS) evolution ; centromere ; sSMC ; Prospero autumnale complex ; next-generation sequencing ; Drosophila ; host/parasite interaction ; Apodemus peninsulae ; genome evolution ; evolution ; teleost ; chromosome evolution ; microdissected DNA probes ; controlling element ; mobile element ; RNA-Seq ; karyotypes ; karyotypic characteristics ; RepeatExplorer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 34
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Several epidemiological studies have demonstrated that oxidative stress is associated with a number of health disorders, including cardiovascular malfunction, certain types of cancer, diabetes mellitus, many other auto-immune diseases, and even ageing. The body possesses multiple mechanisms to counteract oxidative stress, which employ antioxidant compounds that are either naturally generated in situ (endogenous antioxidants) or externally supplied through food (exogenous antioxidants). These antioxidants are able to counteract oxidative stress, thanks to their ability to neutralize excess free radicals and protect the cellular lipids, proteins, and DNA from molecular damage. Exogenous antioxidants from the diet are of increasing interest because of their beneficial role in maintaining good health and in preventing chronic diseases. Indeed, a diet rich in dietary antioxidants, especially from fruits and vegetables, has been correlated with a successful prevention and lower incidence of several degenerative pathologies, including obesity, diabetes, cardiovascular diseases, and cancer. This Special Issue of Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature, examining the role of diets rich in antioxidant compounds in the prevention of chronic diseases and the characteristics of the antioxidants included in such diets.
    Keywords: QH301-705.5 ; antioxidants ; chronic diseases ; dietary supplementation ; human health ; prevention ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/png
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 35
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Recent special issues in various journals have focused on “urban ecosystem services”. There is also an increasing amount of studies on “urban ecology”, “urban tree management”, “arboriculture”, “urban biodiversity”, and “ecosystem services” from wildland forests. This Special Issue aims to fill a void and focus on the socio-ecological diversity and the economic value of the ecosystem services from urban and peri-urban forests. Urban and peri-urban forests are tree dominated ecosystems in and near human settlements, while ecosystem services are the direct economic, social, and environmental benefits provided by their structural components and ecological functions.
    Keywords: QH301-705.5 ; GE1-350 ; Perceptions and attitudes ; Climate change ; Socio-ecological systems ; Ecosystem service tradeoffs ; Non-market valuation ; Urban forest structure and biodiversity ; Management and planning ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 36
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-02
    Description: Sustainability is an urgent developmental task for our society and is attracting increasing attention. Therefore, higher education institutions (HEIs) are also called upon to deal theoretically, conceptually, methodically, critically, and reflectively with the associated challenges and the processes and conditions of transformation in order to contribute to sustainable development. How can complex organisations such as HEIs succeed in initiating and maintaining the process of sustainable development within their own institutions and make it a permanent responsibility? How can as many protagonists as possible be persuaded to get involved in sustainable development? This book deals with the promotion of sustainable university development and provides an overview of how universities can be organised sustainably and how sustainable development can be implemented in their various functional areas. In the sense of a “whole-institution approach”, which encompasses entire HEIs, the focus is not only on the core areas of teaching (higher education for sustainable development) and research (sustainability in research) but, also, on the operational management of HEIs. In addition, this book focuses on sustainability governance and transfer for sustainable development at HEIs as cross-disciplinary issues.
    Keywords: higher education institutions ; implementation ; organisational factors ; sustainable development ; interpretative structural modelling (ISM) ; higher education institutions (HEIs) ; cross-sector collaboration ; multi-professional collaboration ; transdisciplinary research ; narrative analysis ; sensemaking ; whole institution approach ; organizational networks ; constant comparative analysis ; athletic departments ; higher education ; sustainability ; loose coupling ; shared governance ; United States ; intellectual capital ; performance ; quality of life ; sustainability assessment ; environmental management performance ; German-speaking countries ; survey ; whole-institution approach ; competencies ; knowledge ; values ; case study ; discourse analysis ; environment ; Global South ; Sustainable Development Goals ; universities’ transformation ; sustainability assessment tool ; sustainability governance ; systems theory ; governance equalizer ; politics ; profession ; organization ; public ; organizational culture ; Germany ; sustainability in science ; transformative science ; grammar of responsibility ; ethics of knowledge ; universities as echo chambers of society ; catalytic science ; universities ; organizational change ; higher education for sustainable development (HESD) ; sustainability transitions ; SD ; alliances ; university ; transfer ; practitioner–university partnership ; societal impact ; education for sustainable development ; higher education development ; sustainable university development ; systemic development ; inter-organizational networks ; worldviews ; societal transformation ; systemic transformation ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JN Education
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 37
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Outbreaks of crown-of-thorns starfish (Acanthaster spp.) are a major contributor to ongoing coral loss on reefs throughout the Indo-Pacific, thereby jeopardizing productivity and biodiversity of these important marine ecosystems. Controlling outbreak populations of Acanthaster spp. is considered one of the most promising strategies to halt or reverse widespread declines in live coral cover. Effective management of crown-of-thorns starfish is, however, conditional on improved understanding of their biology and ecology. While crown-of-thorns starfish are arguably the most extensively studied of any single coral reef species, there remain considerable gaps in our knowledge of their basic biology and ecology. This edited monograph presents the latest research and significant advances in understanding and managing outbreaks of crown-of-thorns starfish.
    Keywords: QH301-705.5 ; Coral reefs ; Habitat loss ; Disturbance ; Ecology ; Management ; Acanthaster spp. ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 38
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Alternative treatment modes for antibiotic-resistant bacterial pathogens have become a public health priority. Bacteriophages are bacterial viruses that infect and lyse bacterial cells. Since bacteriophages are frequently bacterial host species-specific and can often also infect antibiotic-resistant bacterial cells, they could represent ideal antimicrobials for fighting the antibiotic resistance crisis. The medical use of bacteriophages has become known as phage therapy. It is widely used in Russia, where phage cocktails are sold in pharmacies as an over-the-counter drug. However, no phage product has been registered for medical purposes outside of the former Soviet Union. The current Special Issue of Viruses contains a collection of papers from opinion leaders in the field who explore hurdles to the introduction of phage therapy in western countries. The articles cover diverse topics ranging from patent to regulatory issues, the targeting of suitable bacterial infections, and the selection and characterization of safe and efficient phage cocktails. Phage resistance is discussed, and gaps in our knowledge of phage–bacterium interactions in the mammalian body are revealed, while other articles explore the use of phages in food production and processing.
    Keywords: QH301-705.5 ; QR1-502 ; Q1-390 ; alginate ; abortive infection ; n/a ; bacterial resistance ; bacteriophages ; ATMP ; MALDI-MS ; adaptation ; Bacteriophage ; horizontal gene transfer ; adaptive immunity ; co-evolution ; Listeria ivanovii ; personalised medicines ; pH stability ; phage-human host interaction ; vB_SauM-fRuSau02 ; antimicrobial resistance ; phagodisinfection ; biofilm ; capsule depolymerase ; animal model ; phage cocktails ; Enterococcus ; cases report ; zoonosis ; resistance ; magistral formula ; experimental therapy ; Belgium ; phage therapy ; E. faecalis ; nontraditional antibacterial ; industrial phage application ; Democratic Republic of the Congo ; OrthoMCL ; Germany ; high-throughput sequencing ; antimicrobial ; infection ; antibiotic therapy ; Kayvirus ; phages ; Twortlikevirus ; bacterial disease ; human host ; Pseudomonas aeruginosa ; phage ; multidrug-resistant bacteria ; bacterial infection ; Salmonella Typhi ; rhamnopolysaccharide ; compassionate use ; crop production ; compounding pharmacy ; antimicrobial resistance (AMR) ; best practices ; bacteriophage efficacy ; phage sensitivity ; antibiotic-resistance ; antibiotic ; lysins ; PTMP ; Escherichia coli ; typhoid fever ; patent landscape ; phage preparation ; innate immunity ; anti-phage antibodies ; immunology ; Staphylococcus aureus ; global health ; clinical trial ; adsorption ; Brussels ; phage-resistance ; Galleria mellonella ; science communication ; history of science ; virus–host interactions ; foodborne illness ; prophage ; resistance management ; biofilms ; IND ; immunomodulation ; frequency of resistance ; capsule ; gastrointestinal tract ; phage-host interactions ; disinfection ; production ; bacteriophage therapy ; bacteriophage ; Staphylococcus ; magistral preparation ; extended-spectrum beta lactamases (ESBL) ; Viral proteins ; antibiotic resistance ; genomics ; phage biocontrol ; therapy ; target selection ; viral genomes ; evolution ; pharmaceutical paradigm shift ; personalized medicine ; pharmaceutical legislation ; food safety ; regulation ; virulence ; developing countries ; infectious disease ; regulatory framework ; sustainable agriculture ; Klebsiella pneumoniae ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 39
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [Estrogen receptors (ERs) are typical members of the superfamily of nuclear receptors that mainly function as ligand-inducible transcription factors that bind chromatin, as homodimers, at specific response elements. A tight reciprocal coupling between rapid ‘non-genomic’ and ‘genomic’ ER actions may also occur in many physiological processes. ERs have long been evaluated for their roles in controlling the expression of genes involved in vital cellular processes such as proliferation, apoptosis, and differentiation. Therefore, given the various and pleiotropic functions of ERs, the dysregulation of their pathways contributes to several diseases such as the hormone-dependent breast; endometrial and ovarian cancers; and neurodegenerative diseases, cardiovascular diseases, and osteoporosis. In this printed edition of the Special Issue, “Molecular Pathways of Estrogen Receptor Action”, promising results on understanding the mechanisms underlying ER-mediated effects in various pathophysiological processes are represented, covering different roles of ER pathways in the tumorigenesis, the resistance to endocrine therapy, the dynamics of 3D genome organization, and cross-talk with other signaling pathways. This Special Issue also provides insight into the emerging roles of estrogen-signaling pathways in lung cancer, the tumor microenvironment, and the immune system.]
    Keywords: QH301-705.5 ; Estrogens and estrogen receptors ; Cell signaling ; Physiopathology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 40
    Publication Date: 2024-04-05
    Description: While international efforts in the development of short rotation woody crops (SRWCs) have historically focused on the production of biomass for bioenergy, biofuels, and bioproducts, research and deployment over the past decade has expanded to include broader objectives of achieving multiple ecosystem services. In particular, silvicultural prescriptions developed for SRWCs have been refined to include woody crop production systems for environmental benefits such as carbon sequestration, water quality and quantity, and soil health. In addition, current systems have been expanded beyond traditional fiber production to other environmental technologies that incorporate SRWCs as vital components for phytotechnologies, urban afforestation, ecological restoration, and mine reclamation. In this Special Issue of the journal Forests, we explore the broad range of current research dedicated to our topic: International Short Rotation Woody Crop Production Systems for Ecosystem Services and Phytotechnologies
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; rhizospheric soil ; allocation ; acidic soil ; abandoned farmland ; carbon sequestration ; bioenergy ; mycorrhizal fungi ; leaf area index ; foliar nutrient and metal concentration ; aboveground biomass ; inoculation ; stocking level ; site reclamation ; willow ; Salix ; spacing trial ; agricultural field experiment ; Populus ; Populus canadensis ; species variation ; ecosystem services ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 41
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: Disasters such as earthquakes, cyclones, floods, heat waves, nuclear accidents, and large scale pollution incidents take lives and cause exceptionally large health problems. The majority of large-scale disasters affect the most vulnerable populations, which are often comprised of people of extreme ages, in remote living areas, with endemic poverty, and with low literacy. Health-related emergency disaster risk management (Health-EDRM) [1] refers to the systematic analysis and management of health risks surrounding emergencies and disasters; it plays an important role in reducing hazards and vulnerability along with extending preparedness, response, and recovery measures. This concept encompasses risk analyses and interventions, such as accessible early warning systems, timely deployment of relief workers, and the provision of suitable drugs and medical equipment, to decrease the impact of disaster on people before, during, and after disaster events. Disaster risk profiling and interventions can be at the personal/household, community, and system/political levels; they can be targeted at specific health risks including respiratory issues caused by indoor burning, re-emergence of infectious disease due to low vaccination coverage, and gastrointestinal problems resulting from unregulated waste management. Unfortunately, there has been a major gap in the scientific literature regarding Health-EDRM. The aim of this Special Issue of IJERPH was to present papers describing/reporting the latest disaster and health risk analyses, as well as interventions for health-related disaster risk management, in an effort to address this gap and facilitate major global policies and initiatives for disaster risk reduction.
    Keywords: thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 42
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: 'The Future of Catholic Theological Ethics' undertakes a search for new ways of making Catholic theological ethics relevant. It engages with a ground-breaking publication 'Reframing Catholic Theological Ethics' (Oxford University Press, 2016) by Joseph Selling, Emeritus Professor of Moral Theology, Catholic University Leuven. Selling opens the volume with a summary of the approach he developed in the above work. The papers presented here cover several major themes that, traditionally, Catholic theological ethics have considered but, according to the authors of the papers, need revisiting. Amongst these themes are: conscience, virtue, natural law, authority, ecumenism, the human person and the theology of theological ethics. The writers represent a variety of approaches, geographical locations and while most of them are Roman Catholic, there is an imbedded ecumenism and interreligious and inter-cultural slant in several discussions. The authors agree that Catholic theological ethics, in order to be relevant, it needs to become more context-sensitive, ecumenical, practice-based, experience-oriented, continuously discerning, pedagogically wide-ranging and theologically articulate. It must be unceasingly willing to review and renew its method as well as revisit its key concepts. It must neither dismiss its long tradition nor stick to its single interpretation.
    Keywords: H1-99 ; HIV/AIDS ; global South ; global North ; conscience ; love ethics ; social ethics ; method of moral theology ; virtues ; Catholic ethics ; virtue ethics ; Thomas Aquinas ; normativity ; Duns Scotus ; Karl Barth ; Pope Francis ; ecumenism ; teleology ; sexual ethics ; contextualisation ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
    Format: image/png
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 43
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The majority of carbon stored in the soils of the world is stored in forests. The refractory nature of some portions of forest soil organic matter also provides the slow, gradual release of organic nitrogen and phosphorus to sustain long term forest productivity. Contemporary and future disturbances, such as climatic warming, deforestation, short rotation sylviculture, the invasion of exotic species, and fire, all place strains on the integrity of this homeostatic system of C, N, and P cycling. On the other hand, the CO2 fertilization effect may partially offset losses of soil organic matter, but many have questioned the ability of N and P stocks to sustain the CO2 fertilization effect.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; polyphenols ; aluminum accumulator ; near natural forest management ; chloroform fumigation extraction ; soil structure ; soil enzymes ; manure pelleting ; microbial biomass ; Oxisol ; biolability ; soil nutrients ; second production cycle ; PLFA ; pyrolysis ; Eucalyptus sp. ; Cunninghamia lanceolata plantation ; carbon ; the Three Gorges Reservoir ; revegetation ; carbon distribution index ; climate change ; seasons ; annual increment average ; topography ; humic substances ; litter N ; soil fertility ; climate zone ; nutrient cycling ; Daxing’an Mountains ; carbon mineralization ; nitrification ; 31P nuclear magnetic resonance spectroscopy (31P NMR) ; organic matter ; throughfall ; forest soil ; dissolved organic carbon (DOC) ; P species ; stoichiometric homeostasis ; dissolved organic matter (DOM) ; soil organic matter fraction ; variable-charge soils ; ammonium ; nitrate ; soil degradation ; soil P fractions ; seasonal trends ; ammonia-oxidizing bacteria ; nitrogen dynamics ; net primary productivity ; soil microbial communities ; beech forests ; soil pH ; wood volume ; temperature ; northern temperate ; multilevel models ; Pinus massoniana plantation ; ammonia-oxidizing archaea ; P stock ; stand density ; P resorption efficiency ; forest types ; soil greenhouse gas flux ; enzyme activities ; soil N ; alpine forest ; moisture gradient ; climate ; climatic factors ; soil available phosphorus ; microbial activity ; soil available nitrogen ; leaf N:P ratio ; stemflow ; Chamaecyparis forest ; charcoal ; gross nitrogen transformations ; principal component analyses ; information review ; manuring ; stand age ; tree-DOM ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 44
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The emergence of marine and freshwater toxins in geographical areas where they have never been reported before is a concern due to the considerable impact on (sea)food contamination, and consequently, on public health. Several groups of marine biotoxins, in particular tetrodotoxins, ciguatoxins, and palytoxins, are included among the relevant marine biotoxins that have recently emerged in several coastal areas. A similar situation has been observed in freshwater, where cyanobacterial toxins, such as microcystins, could end up in unexpected areas such as the estuaries where shellfish are cultivated. Climate change and the increased availability of nutrients have been considered as the key factors in the expansion of all of these toxins into new areas; however, this could also be due to more intense biological invasions, more sensitive analytical methods, or perhaps even an increased scientific interest in these natural contaminations. The incidences of human intoxications due to the consumption of seafood contaminated with these toxins have made their study an important task to accomplish in order to protect human health. This Special Issue has a focus on a wide variety of emerging biotoxin classes and techniques to identify and quantify them.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; C-CTX-1 ; non-targeted analysis ; ciguatera fish poisoning ; suspects screening ; neurodegeneration ; adaptation ; LC-HRMS ; paralytic shellfish toxins ; LC-MS/MS ; animal toxins ; identification ; method characterization ; caribbean ciguatoxins ; oral toxicity ; water flea ; quorum sensing ; eutrophication ; beta-methyl-amino-l-alanine ; dynamics simulation ; thermal water ; spent medium ; Microcystis ; Gambierdiscus ; gambierdiscus ; whole genome sequencing ; palytoxin ; conotoxin ; ovatoxins ; cyanobacterial toxin ; BMAA ; Ciguatera fish poisoning ; Rastrineobola argentea ; calcium-activated K+ ion channel ; toxicity equivalence factor ; NMR spectroscopy ; N2a ; PPIA ; marine biotoxins ; Daphnia magna ; ELISA ; disulfide-rich peptide ; food chain ; ShK-like peptide ; voltage-gated K+ ion channel ; targeted analysis ; Chinese yellow catfish ; marine ; macaronesia ; neuroblastoma bioassay ; marine toxins ; acute toxicity ; algal–bacterial relationship ; mass spectrometry ; tetrodotoxins ; saxitoxin ; toxicology ; cationization ; seafood safety ; evolution ; cyanotoxins ; toxin genes ; zoantharian ; spatial variability ; dopaminergic neurons ; tetrodotoxin ; bivalve mollusks ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 45
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Tea, made from the leaves of the Camellia senenisis plant, is the second most consumed beverage worldwide after water. Accumulating evidence from cellular, animal, epidemiological and clinical studies have linked tea consumption to various health benefits, such as chemoprevention of cancers, chronic inflammation, heart and liver diseases, diabetes, neurodegenerative diseases, etc. Although such health benefits have not been consistently observed in some intervention trials, positive results from clinical trials have provided direct evidence supporting the cancer-protective effect of green tea. In addition, numerous mechanisms of action have been suggested to contribute to tea’s disease-preventive effects. Furthermore, effects of the processing and storage of tea, as well as additives on tea’s properties have been investigated.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; cell cycle arrest and apoptosis ; neuroblastoma ; salivary ?-amylase activity ; cancer apoptosis ; yaupon holly ; bioaccessibility ; fracture ; p53 ; tea ; Liubao tea ; BE(2)-C ; matrix metalloproteinase-1 (MMP-1) ; catechin ; renal stone ; oxalate ; protein expression ; 67LR ; Alzheimer’s disease ; EGCG ; nutraceutical ; diseases ; anti-oxidant ; heme oxygenase-1 ; polyphenol ; anxiety ; matcha ; ERCC1/XPF ; neuro-sphere ; tea consumption ; theanine ; Rosmarinic acid ; yerba mate ; hypercalciuria ; gene expression ; microbiota ; cohort study ; histone deacetylase 2 (HDAC2) ; guayusa ; nuclear factor erythroid 2-related factor 2 (Nrf2) ; DNA repair ; mRNA expression ; caffeine ; chemoprevention ; cisplatin ; 6-OH-11-O-hydroxyphenanthrene ; adrenal hypertrophy ; hepatic damage ; anti-photoaging ; cell death ; green tea ; kudingcha ; suberoylanilide hydroxamic acid (SAHA) ; epigallocatechin gallate (EGCG) ; stress-reduction ; calcium oxalate monohydrate ; Camellia sinensis ; chemoresistance ; tea polyphenols ; green tea polyphenols ; green tea catechins ; N-MYC ; cancer ; epigallocatechin-gallate (EGCG) ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 46
    Publication Date: 2024-04-05
    Description: Integrative omics of plants in response to stress conditions play more crucial roles in the post-genomic era. High-quality genomic data provide more deeper understanding of how plants to survive under environmental stresses. This book is focused on concluding the recent progress in the Protein and Proteome Atlas in plants under different stresses. It covers various aspects of plant protein ranging from agricultural proteomics, structure and function of proteins, and approaches for protein identification and quantification.
    Keywords: QH301-705.5 ; QK1-989 ; Q1-390 ; phosphoproteomics ; GLU1 ; somatic embryogenesis ; CHA-SQ-1 ; nitrogen fertilizer ; chilling stress ; differentially abundant proteins ; ATP synthase ; photosynthetic parameters ; photosynthesis ; constitutive splicing ; phosphorylation ; Jatropha curcas ; plants under stress ; postharvest freshness ; Alternanthera philoxeroides ; rubber latex ; Millettia pinnata ; molecular and biochemical basis ; filling kernel ; drought stress ; comparative proteomic analysis ; domain ; micro-exons ; phylogeny ; phos-tagTM ; E. angustifolia ; root cell elongation ; ABA ; pollen abortion ; lncRNA ; transcriptome ; radish ; redox homeostasis ; Nelumbo nucifera ; sugar beet ; shotgun proteomics ; proteomes ; high-temperature stress ; post-genomics era ; model plant ; salt tolerance ; miRNA ; wheat ; physiological response ; stress ; visual proteome map ; transcriptional dynamics ; leaf ; maize ; Dunaliella salina ; phosphatidylinositol ; S-adenosylmethionine decarboxylase ; Gossypium hirsutum ; flavonoid biosynthesis ; phosphatase ; wood vinegar ; heat shock proteins ; silicate limitation ; purine metabolism ; natural rubber biosynthesis ; ancient genes ; cotton ; rubber grass ; abiotic stress ; heat stress ; maturation ; low-temperature stress ; molecular basis ; transcriptome sequencing ; ROS scavenging ; widely targeted metabolomics ; transdifferentiation ; seed development ; alternative splicing ; cultivars ; inositol ; salt stress ; chlorophyll fluorescence parameters ; proteome ; carbon fixation ; AGPase ; transcript-metabolite network ; molecular mechanisms ; Triticum aestivum L. ; Zea mays L. ; ROS ; label-free quantification ; woody oilseed plants ; heat-sensitive spinach variety ; MIPS ; quantitative proteomics ; regulated mechanism ; two-dimensional gel electrophoresis ; potassium ; glutathione ; Salinity stress ; integrated omics ; diatom ; ATP synthase CF1 alpha subunit (chloroplast) ; root ; proteome atlas ; brittle-2 ; mass spectrometry ; genomics ; Taraxacum kok-saghyz ; cytomorphology ; proteomics ; arbuscular mycorrhizal fungi ; signaling pathway ; proteomic ; loss-of-function mutant ; rice ; seedling ; wucai ; leaf sheath ; root and shoot ; antioxidant enzyme ; exon-intron structure diversity ; isobaric tags for relative and absolute quantitation ; regulation and metabolism ; concerted network ; drought ; heat response ; VIGS ; iTRAQ ; nitrogen use efficiency (NUE) ; stem ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 47
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Special Issue “Extractable and Non-Extractable Antioxidants” gives an updated view on antioxidants—both in their extractable and non-extractable form—in the different food groups, their products thereof, and food preparations as well as byproducts and biomass waste. The potential beneficial properties of these compounds and nutraceutical formulations are described in the various studies covered in this Special Issue.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; biorefinery ; polyphenols ; polymerization ; n/a ; black teas ; nutrient ; ultrasound assisted extraction ; cyclodextrin ; HPLC-ESI/MS ; legumes ; degradation ; LC-ESI-Q-TOF-MS ; antioxidant activity ; forest residues ; multivariate analysis ; bio-based ; chemometrics ; extractable polyphenols ; extractable compounds ; pre-column HPLC method ; Cagnulari marc ; antioxidant capacity ; flour ; total polyphenol content (TPC) ; digestibility ; ferric reducing antioxidant power (FRAP) ; natural antioxidants ; dietary assessment. ; eggplant ; antioxidant ; botanicals ; anthocyanins ; trans-cinnamaldehyde ; anti-inflammation ; cereals ; functional ingredient ; food composition database ; agglomerative hierarchical clustering ; circular economy ; fermentation ; Aloysia triphylla ; Naviglio Extractor® ; flavonols glycosides ; self-inclusion ; phenolic contents ; grape seed ; integrated food research ; antioxidants ; dedicated databases ; phenolic compounds ; non-extractable compounds ; value-added by-products ; phenolic acids ; dietary supplements ; berries jam ; phenolics ; inclusion complex ; sour cherry ; Pleurotus ostreatus ; catechins ; proanthocyanidins ; Chinese mistletoes ; nuclear magnetic spectroscopy ; nitric oxide scavengers ; quercitrin ; endothelial cell ; polyphenolic compounds ; Italian popular recipes ; green extraction ; non-extractable polyphenols ; classic extraction ; study approach ; daidzein ; ?-cyclodextrin ; Camellia sinensis ; antioxidant properties ; digestive enzyme ; extractable ; bioactive compounds ; principal component analysis ; non-extractable ; oxidative stress ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 48
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: This Special Issue of Genealogy explores the topic of “Intergenerational Trauma and Healing”. Authors examine the ways in which traumas (individual or group, and affecting humans and non-humans) that occurred in past generations reverberate into the present and how individuals, communities, and nations respond to and address those traumas. Authors also explore contemporary traumas, how they reflect ancestral traumas, and how they are being addressed through drawing on both contemporary and ancestral healing approaches. The articles define trauma broadly, including removal from homelands, ecocide, genocide, sexual or gendered violence, institutionalized and direct racism, incarceration, and exploitation, and across a wide range of spatial (home to nation) and temporal (intergenerational/ancestral and contemporary) scales. Articles also approach healing in an expansive mode, including specific individual healing practices, community-based initiatives, class-action lawsuits, group-wide reparations, health interventions, cultural approaches, and transformative legal or policy decisions. Contributing scholars for this issue are from across disciplines (including ethnic studies, genetics, political science, law, environmental policy, public health, humanities, etc.). They consider trauma and its ramifications alongside diverse mechanisms of healing and/or rearticulating self, community, and nation.
    Keywords: Holocaust ; survivors ; second generation ; transgenerational transmission ; trauma ; Grossman ; Armenian ; genocide ; 1915 ; human rights violation ; Christianity ; law enforcement violence ; living with trauma ; impunity ; collective trauma ; dreams ; psychoanalysis ; literature ; Zabuzhko ; transgenerationally transmitted trauma ; indigenous wisdom ; disrupted attachment ; cultural restoration ; well-being ; survivance ; sobrevivencia ; healing ; struggle ; mothers ; movements ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 49
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The book ""Quality and Production of Forage"" is intended to keep readers updatedon the developments occurring in this field. As it is apparent that livestockanimals are important throughout the world because of the meat, milk and eggthey produce, knowledge about the forages available to animals must also beconsidered for increased production, quality and efficiency. This book providesinformation that readers will find considerably invaluable about forage feeds, suchas grass, legumes, and straw. The book is composed of ten papers, focusing on awide range of research activities and topics that feature the following concepts offorage: the effect of conservation method on forage protein value; Microbial thecomposition and mycotoxin content in forage; genetic diversity of forages; timelysowing to maximize yield for both grain and biomass; ensiling treatments onforage quality; the qualitative characteristics of different accessions of new foragespecies; forage policy influencing feed costs; feeding forage on animal health;high-protein tropical forages as alternative sources for poultry; impact of foragesin poultry diet and significance of forages in sustainable poultry productionsystems. This book will be an invaluable reference for students and professionalsin agricultural science and grassland and animal husbandry researches.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; annual clover ; corn ; plant height ; forage production ; feed costs ; wilting ; population density ; Moringa oleifera ; alfalfa ; livestock ; digestibility ; hay ; sowing date ; biomass production ; clover ; tropical forages ; sustainability ; alternative protein ; plant ; animal ; dry matter ; genetic diversity ; chicken ; zearalenone ; production system ; forage ; energy balance ; grain yield ; nutritional composition ; deoxynivalenol ; grass ; silage ; policy ; path analysis ; poultry ; in vitro organic matter digestibility ; nitrogen ; nitrogen balance ; beneficial use ; lucerne ; forage yield ; anti-nutritional factors ; N fixation ; fungi ; planting ; markers ; crude protein ; epiphytic microflora ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 50
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: • The aim of this Special Issue is to examine the current major topics concerning the use of social media and big data in sustainable tourism practices and to encourage interdisciplinary discussion among researchers regarding these issues. • This Special Issue covers all relevant areas of the debate, including 15 selected papers based on the following core ideas: smart tourism and big data, social media in the tourism industry, and online reviews and tourist behaviors. • This Special Issue discusses wide-ranging topics and research questions with regard to the smart tourism city, the impact of social media, online reviews, and tourist behaviors, and it represents a call to action for scholars to engage with broader social issues.
    Keywords: shared short-term rental ; sustainable tourism ; online reviews ; purchase decisions ; social networks ; social media ; Twitter ; tourism ; volunteered geographic information ; OpenStreetMap ; nighttime light remote sensing ; social media usage characteristics ; Big Five personality traits ; personality characteristics ; social characteristics ; information characteristics ; e-WOM ; trust ; brand equity ; brand awareness ; brand image ; topic modeling ; latent Dirichlet allocation ; tourism 4.0 ; online travel agency ; online review ; text analytics ; improve customer satisfaction ; inductive approach ; dimensions of interest ; era of big data ; cultural consensus ; cultural consonance ; online hotel reviews ; trustworthiness ; technology acceptance model ; Generation Y ; overtourism ; organization-public relationship ; place-visitor relationship ; crowdfunding ; consumption value ; inner innovativeness ; perceived risk ; the intention to visit festival ; oblique photography ; mobile applications ; musicals ; city branding ; SNSs ; orientation ; smart tourism city ; smart tourism ; smart city ; sustainable development ; COVID-19 ; tourist destinations ; destination image ; stakeholders ; rural tourism ; social networking service ; theory of planned behavior ; social media use ; graffiti ; text mining ; social network analysis ; travel reality variety program ; viewing motivation ; viewing satisfaction ; presence ; attitude toward tourism destination ; spatial variance ; multiscale GWR ; sharing economy ; Airbnb ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 51
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Iron is an essential element for almost all organisms, a cofactor playing a crucial role in a number of vital functions, including oxygen transport, DNA synthesis, and respiration. However, its ability to exchange electrons renders excess iron potentially toxic, since it is capable of catalyzing the formation of highly poisonous free radicals. As a consequence, iron homeostasis is tightly controlled by sophisticated mechanisms that have been partially elucidated. Because of its biological importance, numerous disorders have been recently linked to the deregulation of iron homeostasis, which include not only the typical disorders of iron overload and deficiency but also cancer and neurodegenerative diseases. This leads iron metabolism to become an interesting therapeutic target for novel pharmacological treatments against these diseases. Several therapies are currently under development for hematological disorders, while other are being considered for different pathologies. The therapeutic targeting under study includes the hepcidin/ferroportin axis for the regulation of systemic iron homeostasis, complex cytosolic machineries for the regulation of the intracellular iron status and its association with oxidative damage, and reagents exploiting proteins of iron metabolism such as ferritin and transferrin receptor. A promising potential target is a recently described form of programmed cell death named ferroptosis, in which the role of iron is essential but not completely clarified. This Special Issue has the aim to summarize the state-of-the-art, and the latest findings published in the iron field, as well as to elucidate future directions.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; developmental ; Anemia of chronic disease ; neurodegeneration ; supplementation ; MHC ; iron chelation therapy ; osteoblast ; serum biomarker ; FeSO4 ; haptoglobin ; prevention ; brain development ; pituitary ; trauma ; hepcidin ; Alzheimer’s disease ; chaotropes ; social behavior ; Africa ; macrophage ; anemia of inflammation ; Tfr2 ; chelation ; cardiomyocyte ; IV iron therapy ; Oxidative stress ; treatment ; chronic kidney disease ; iron homeostasis ; oxygen sensing ; iron chelators ; age-related macular degeneration (AMD) ; pharmaceutical targets ; non-transferrin-bound iron (NTBI) ; iron dextran ; pulmonary arterial hypertension ; labile iron ; low and middle income countries ; ferroportin ; gut microbiota ; reducibility ; non-HFE ; oxidative stress ; antitumor compound ; senescence ; electron transfer ; nanotechnology ; iron deficiency ; neonatal period ; heme oxygenase ; hypoxia ; Anemia ; NCOA4 ; patient blood management ; microbiome ; anemia ; iron mobilization ; iron release ; phlebotomy ; peritoneal dialysis ; Friedreich Ataxia ; ferritin ; CD8+ T cells ; M cells ; neurodegenerative disease ; NaFeEDTA ; vascular calcification ; cinnamic acid derivatives ; oral iron salts ; lipid ; acute lung injury ; Iron-sulfur ; Interleukin-6 ; neurodegeneration with brain iron accumulation ; macrophages ; erythroblastic islands ; cystic fibrosis ; neuroimmune responses ; flavin nucleotide ; hemopexin ; Iron chelators ; nutrient iron ; developing countries ; hereditary hypoferritinemia ; iron ; cancer ; Indonesia ; n/a ; Hfe ; HFE ; chronic heart failure ; iron supplementation ; intestinal inflammation ; TNF ; chelators ; hemolysis ; children ; pulmonary arterial smooth muscle cells ; cytokines ; didox ; intravenous iron ; T lymphocytes ; colorectal cancer ; infants ; liver ; ferritinophagy ; hereditary hyperferritinemia ; SCFA ; rheumatoid arthritis ; membrane interactions ; Sucrosomial® iron ; lung ; Kupffer cell ; iron chelation ; erythrophagocytosis ; acute kidney injury ; neurophysiology ; iron transporters ; iron absorption ; infection ; ferroptosis ; fluorescent iron chelator ; neonatal ; SNC ; immunity ; mycobacteria ; non-haem iron ; natural history ; 3-hydroxy-4-pyridinone ; haem ; inflammation ; bone homeostasis ; cardiovascular disease ; heme ; heme homeostasis ; protein binding ; brain ; iron deficiency anemia ; Fe2+-chelating activity ; bioengineering ; Mek/Erk ; Bmp/Smad ; iron delivery ; genetic hemochromatosis ; osteoclast ; histidine ; rhodamine ; COPD ; hemorrhage ; antibacterial activity ; bacteria ; SLC40A1 ; transferrin receptor ; drug delivery ; nanocage ; soybean seed ferritin ; pig ; iron metabolism ; kidney ; innate immunity ; cataracts syndrome ; erythropoiesis ; obesity ; mucosal immunity ; iron overload ; fluorophore ; binding ability ; inflammatory bowel disease (IBD) ; osteoporosis ; biomarker ; bioavailability ; adverse event profile ; metabolism ; iron-carbohydrate complex ; kinetics ; flavonoids ; iron regulatory proteins ; lung infection ; non transferrin bound iron ; central nurse macrophage ; iron processing ; malaria ; neurodegenerative diseases ; multifunctional iron chelators ; retina ; neuroinflammation ; anti-hepcidin therapy ; lung diseases ; anaemia ; RRM2 ; cognition ; mitochondria ; therapy ; NBIA ; red pulp macrophage ; efficacy ; hemochromatosis ; tolerability ; oral iron therapy ; growth ; venesections ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 52
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Targeted therapy has developed significantly in the last one and half decades, prescribing specific medications for treatment of particular diseases, such as cancer, diabetes, and heart disease. One of the most exciting recent developments in targeted therapies was the isolation of disease-specific molecules from natural resources, such as animal venoms and plant metabolites/toxins, for use as templates for new drug motif designs. In addition, the study of venom proteins/peptides and toxins naturally targeted mammalian receptors and demonstrated high specificity and selectivity towards defined ion channels of cell membranes. Research has also focsed intensely on receptors. The focus of this Special Issue of Toxins addressed the most recent advances using animal venoms, such as frog secretions, bee/ant venoms and plant/fungi toxins, as medicinal therapy. Recent advances in venom/toxin/immunotoxins for targeted cancer therapy and immunotherapy, along with using novel disease-specific venom-based protein/peptide/toxin and currently available FDA-approved drugs for combinationtreatments will be discussed. Finally, we included an overview of select promising toad/snake venom-based peptides/toxins potentially able to address the forthcoming challenges in this field. Both research and review articles proposing novelties or overviews, respectively, were published in this Special Issue after rigorous evaluation and revision by expert peer reviewers.
    Keywords: QH301-705.5 ; Q1-390 ; cane toad ; n/a ; B cell non-Hodgkin lymphoma ; Malaysian cobras ; complement system ; decay accelerating factor ; neuroblastoma ; atopic dermatitis ; complement dependent cytotoxicity ; antioxidant enzymes ; bacterial adhesion ; cancer therapy ; N. kaouthia ; anuran skin secretion ; frog ; Apis mellifera syriaca ; solid phase extraction ; bee venom phospholipase A2 (bvPLA2) ; disintegrin ; toad toxins ; immunotoxins ; ribosome-inactivating proteins ; antimicrobial peptide (AMP) ; drug design ; Moxetumomab pasudotox ; snake venom ; antiviral activity ; in vitro effects ; bombesin-related peptide ; oxidative stress biomarkers ; half-life ; blood vessel formation ; target therapy ; 2 ; MYCN ; indolealkylamines ; Huachansu ; membrane attack complex ; bouganin ; bee venom ; SEM ; anticancer activity ; antimicrobial peptide ; house dust mite extract (DFE) ; mannose receptor ; O. hannah ; bicarinalin ; gastric cells ; melittin ; LC-ESI-MS ; dermaseptin ; smooth muscle ; apoptosis ; anticancer ; N. sumatrana ; Helicobacter pylori ; inflammation ; immunotherapy ; atopic dermatitis (AD) ; immunotoxin ; mantle cell lymphoma ; clearance ; mass spectrometry ; Bougainvillea ; rRNA N-glycosylase activity ; fungal toxin ; skin inflammation ; targeted therapy ; 4-dinitrochlorobenzene (DNCB) ; Bee venom ; VEGF ; Chansu ; bufadienolides ; obsessive–compulsive disorder (OCD) ; BLF1 ; antimicrobial activity ; orellanine ; VB6-845 ; acute lymphoblastic leukemia ; ribosome-inactivating protein ; CD206 ; molecular cloning ; cancer ; CD22 ; eIF4A ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 53
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This textbook is dedicated to the study of genetic factors contributing to autism and includes a collection of original research and review articles related to this topic. Autism spectrum disorders (ASD) include a collection of neurodevelopmental disorders characterized by three recognized behavioral domains involving difficulties in communication, social interaction and repetitive behavior. ASD affects 1 to 2 percent of children and is on the increase worldwide. Significant genetic contributions and mechanisms underlie the causation of ASD. Advances in genetic technology and better awareness have led to a diagnosis of 50 to 70 percent of individuals with ASD primarily due to chromosomal abnormalities, submicroscopic deletions or duplications now identified with high-resolution microarray analysis, next-generation DNA (exome) sequencing of gene variants or mutations, recognized single gene disorders or metabolic disturbances. Through discovery by searching genomic databases and peer-reviewed research articles, nearly 800 genes have been identified to contribute to ASD. Highlights in the field of autism research, discovery and identification of genetic components with characterization will be addressed. Furthermore, reviews of current understanding of the causes and diagnostic approaches for ASD and related syndromes will be presented along with discussion of psychiatric/behavior comorbidities and related features, environmental risk factors, parental attitudes and treatment.
    Keywords: QH301-705.5 ; genetic ; treatment ; genes ; biomarkers ; copy number variants and mutations ; genetic factors ; next generation DNA exome sequencing and functional analysis ; autism and autism spectrum disorders ; causation and etiology ; reviews ; neurodevelopment and physiology testing ; syndromes ; environmental risk factors ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 54
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Special Issue to provide a forum for contemporary studies of the genetics, genomics and phenomics of productivity traits in forage and bioenergy grasses, along with the application of such data to breeding practices and cultivar development.
    Keywords: QH301-705.5 ; forage grass ; biomass ; protein content ; lignocellulosic content ; persistence ; seasonal yield ; soluble carbohydrates ; bioenergy grass ; herbage digestibility ; biofermentation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 55
    Publication Date: 2024-04-05
    Description: Intensive agriculture has generally resulted in higher productivity, but also in a trend towards decreasing levels of agro-biodiversity, which represents a key point in ensuring the adaptability and resilience of agro-ecosystems in the global challenge to produce more and better food in a sustainable way. The biodiversity of vegetable crops includes genetic diversity—both as species diversity (interspecific diversity) and as a diversity of genes within a species (intraspecific diversity) with regard to the vegetable varieties grown—and the diversity of agro-ecosystems (agro-biodiversity). The purpose of this Special Issue is to publish high-quality research papers addressing recent progress and perspectives on different aspects related to the biodiversity of vegetable crops. Original, high-quality contributions that have not yet been published, or that are not currently under review by other journals have been sought. The papers in this Special Issue cover a broad range of aspects and report recent research results regarding agro-biodiversity, which continues to be of significant relevance for both genetic and agricultural applications. All contributions are of significant relevance and could stimulate further research in this area.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; polyphenols ; landraces ; artichoke ; wild edible plants ; microsatellite marker ; mountain agriculture ; HPLC analyses ; Posidonia oceanica (L.) Delile ; apulian landraces ; traditional crops ; genetic reserve ; landrace ; meristem-tip culture ; databases ; long storage time ; Tanzania ; cultivated vegetables ; crop wild relative ; history ; safeguarding ; nutrition ; conservation ; Crithmum maritimum L. ; Italy ; crop population ; Tiggiano carrot ; germplasm ; local varieties ; in situ conservation ; homegardens ; thermotherapy ; genetic resources ; Solanum lycopersicum L. ; plant genetic resources ; recovery ; vegetables ; sanitation ; agriculture ; ecology ; domestication ; heavy metal ; ecotype ; cropping patterns ; virus-sanitation ; agrobiodiversity ; ecotypes ; Apium graveolens ; genetic distance ; genetic variability ; plant genetic resources populations ; food safety ; neglected and underutilized species ; heirloom ; geographical origin area ; seed bank ; climate change adaptation ; bioactive compounds ; genetic differentiation ; growing substrate ; characterization ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 56
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Biomass can be converted to energy, biofuels, and bioproducts via thermochemical conversion processes, such as combustion, pyrolysis, and gasification. Combustion technology is most widely applied on an industrial scale. However, biomass gasification and pyrolysis processes are still in the research and development stage. The major products from these processes are syngas, bio-oil, and char (called also biochar for agronomic application). Among these products, biomass chars have received increasing attention for different applications, such as gasification, co-combustion, catalysts or adsorbents precursors, soil amendment, carbon fuel cells, and supercapacitors. This Special Issue provides an overview of biomass char production methods (pyrolysis, hydrothermal carbonization, etc.), characterization techniques (e.g., scanning electronic microscopy, X-ray fluorescence, nitrogen adsorption, Raman spectroscopy, nuclear magnetic resonance spectroscopy, X-ray photoelectron spectroscopy, and temperature programmed desorption and mass spectrometry), their properties, and their suitable recovery processes.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; n/a ; Boudouard reaction in gasification ; Chinese reed ; underground coal gasification ; food waste ; kinetic models ; fixed bed combustor ; reactor modelling ; AAEMs ; anaerobic digestion ; grape marc ; adsorption isotherms ; Texaco pilot plant ; biomass valorization ; food waste compost ; CH4 adsorption ; gaseous emissions ; polycyclic aromatic hydrocarbon (PAH) ; waste wood ; coconut shells ; kinetic model ; char oxidation ; low-rank coal char ; nutrients ; characteristic time analysis ; kinetic parameters ; ash from biomass ; combustion parameters ; biomass ; thermal characteristics ; biocrude ; reaction kinetics ; sludge cake ; gasification ; pellets ; characterization ; ash layer ; energy recovery efficiency ; internal diffusion resistance ; FT-IR ; giant miscanthus ; pyrolysis ; olive mill solid wastes (OMSWs) ; food-waste biochar ; melting phenomenon ; chemisorption ; steam gasification ; NaCl template ; biomass production ; textural characterization ; desalination ; ash fusion temperature (AFT) ; thermogravimetric analysis ; combustion ; chemical speciation ; sawdust ; NaCl ; effective diffusion coefficient ; kinetics ; breakthrough curves ; biochar engineering ; biochar ; amino acid ; high heating value (HHV) ; salty food waste ; ELECTRE III ; interferences ; multicriteria model ; pyrrole ; interactions ; biogas purification ; fertilisation ; NOx ; pyrolysis conditions ; steam ; partial combustion reaction in gasification ; CO2 adsorption ; poultry slaughterhouse ; hydrothermal carbonization (HTC) ; calorific value ; oxygen enrichment ; porosity ; nitrogen ; hydrothermal carbonization ; thermogravimetric analysis (TGA) ; MTDATA ; activated carbon ; active site ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 57
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Hardwood-dominated temperate forests (mostly in Eastern North America, Europe, North East Asia) provide valuable renewable timber and numerous ecosystem services. Many of these forests have been subjected to harvesting or conversion to agriculture, sometimes over centuries, that have greatly reduced their former extent and diversity. Natural regeneration following harvesting or during post-agricultural succession has often failed to restore these forests adequately. Past harvesting practices and the valuable timber of some species have led to a reduction in their abundance. The loss of apex predators has caused herbivore populations to increase and exert intense browsing pressure on hardwood regeneration, often preventing it. Particularly important are fruit, nut and acorn bearing species, because of their vital role in forest food webs and biodiversity. Restoring hardwood species to natural forests in which they were formerly more abundant will require a number of forest management actions (e.g., resistant hybrids, deer exclosures/protectors, enrichment planting, underplanting, etc.). Similarly, reforesting areas that were once natural forests will also require new silvicultural knowledge. Global warming trends will intensify the need for interventions to maintain the diversity and function of temperate hardwood forests, as well as for increase hardwood reforestation.
    Keywords: QH301-705.5 ; QH540-549.5 ; Q1-390 ; Fagaceae species ; soil disturbance ; non-timber forest products ; precision restoration ; protected landscape area ; tree selection ; cultural diversity ; Quercus rubra ; hardwood restoration ; enrichment planting ; sub-tropical hardwoods ; agroforestry ; herbicide effects ; biological diversity ; competition ; Juglans nigra L. ; understorey ; invasive plants ; wildfire ; forest restoration ; Quercus macrocarpa ; riparian forest restoration ; vegetation management ; assisted migration ; sugar maple ; deer browsing ; species composition ; tolerance ; phosphorus ; growth efficiency index ; floristic quality index ; shelterwood ; Carya cordiformis (Wangenh.) K. Koch ; monitoring ; indicators ; seed predation ; Bioclimatic niche ; non-parametric correlation ; unmanaged forest ; Native Americans ; abandoned agricultural field ; native mixed forests ; tree vigor ; forest diversity ; predation ; weed control ; nitrate ; facilitation ; inventory ; hardwoods ; Mexican tree species ; yellow birch ; tree plantation ; seedling establishment ; deer abundance ; avian guilds ; Pinus strobus L. ; Central Hardwood Forest region ; Pinus strobus ; Durango ; MaxEnt ; Juglans nigra ; oak regeneration ; forest regeneration ; Quercus rubra L. ; deer herbivory ; ecosystem services ; tree shelter ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 58
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: This book provides research and commentary on pharmacy technicians. It demonstrates how the re-design of pharmacy workflow to incorporate more responsibilities for technicians will free up pharmacist time to provide direct patient care. It also highlights that doing so can be accomplished without compromising—and often even improving upon—patient safety. The book also sheds light on employer needs and on new paradigms in pharmacy technician certification, education, and training. However, it also demonstrates the need for improvements in this area, as well as improvements in pharmacy technician quality of work life, advancement opportunities, and wages. Taken together, the papers in this book demonstrate how the results of recent studies help pave the road for the continued evolution of pharmacy care and the optimal deployment of pharmacy workforce personnel.
    Keywords: thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 59
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Currently, in the cosmetic industry, there is an increasing interest in natural extracts, particularly plant extracts. The inclusion of antioxidants in topical formulations may contribute to minimize skin oxidative stress, which has been associated with aging. Many herbal agents used in cosmetics have been selected by a process of ‘trial and error’ and, thus, are used on the basis of experience rather than of experimental investigation. Nevertheless, there is now a growing scientific evidence that plants possess a vast and complex arsenal of active ingredients able not only to calm or smooth but also to actively restore, heal, and protect the human skin. In addition, plant extracts may contain compounds with antimicrobial or other beneficial properties, influencing the formulation of natural and non-chemical cosmetic products. The public trend towards natural and sustainable products is ongoing. Although the term “plant extract” inherently purports their beneficial and benign properties, these products could have adverse reactions in individuals. Therefore, it is essential to ensure quality and safety of these extracts in cosmetic products before embarking on the more arduous task of ensuring efficacy.
    Keywords: QH301-705.5 ; Cosmetic ; In vivo ; Plant extract ; Antioxidant ; In vitro ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/png
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 60
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This book is a printed edition of the Special Issue Fertilizer Application on Crop Yield that was published in Agronomy
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; organic N ; ammonia ; NPK amendments ; corn–soybean rotation ; soil acidity ; phosphorous ; maize yield response to K ; biofertilizer ; agroforestry system ; Copper ; organic farming ; soil nitrogen pools ; net returns ; mineral N ; grain quality ; fertilizer management ; nutrient expert for maize ; sustainability ; organic nutrients ; conservation agriculture ; agronomic response ; S fertilization ; global food demand ; Zea mays L. ; N fertilizer ; nitrogen recovery efficiency ; Bacillus pumilus ; Orychophragmus violaceus L. ; soil erosion ; soil health ; saline tract ; soil K supply ; soil N mineralization ; soil biota ; potassium ; production system ; nitrate reductase activity ; site-specific K management ; Value Cost Ratio ; durum wheat ; conventional farming ; nitrate ; soil organic matter ; grain yield ; integrated nutrient management ; K use efficiency ; rice-wheat system ; forage legume ; nitrogen physiological recovery ; NADH ; chemical fertilizers ; evergreen agriculture ; green manure ; N fertilization ; yield ; NADH-dehydrogenase ; wheat ; site-specific nutrient management ; hybrid rice ; NUE ; balanced use of fertilizers ; growth promotion ; calcium ; humid Mediterranean climate ; Complex I ; rice ; maize ; Zinc ; potentially mineralizable N ; Agrotain® urea ; economics ; nitrate assimilation ; management ; nitrogen uptake ; wheat yields ; nitrogen use efficiency (NUE) ; soil N supply ; maize crop manager ; long-term productivity ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 61
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The sensory properties of foods are the most important reason people eat the foods they eat. What those properties are and how we best measure those properties are critical to understanding food and eating behavior. Appearance, flavor, texture, and even the sounds of food can impart a desire to eat or cause us to dismiss the food as unappetizing, stale, or even inappropriate from a cultural standpoint. This Special Issue focuses on how sensory properties are measured, the specific sensory properties of various foods, and consumer behavior related to which properties might be most important in certain situations and how consumers use sensory attributes to make decisions about what they will eat. This Special Issue contains both research papers and review articles.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; mayonnaise ; Choquet integral ; multi-attribute time-intensity (MATI) data ; foods ; fuzzy measure ; specialty food ; monosodium glutamate (MSG) ; food label ; plant breeding ; consumer test ; perception ; multi-criteria decision-making ; interaction indices ; multicollinearity ; unique food products ; sensory thresholds ; natural ; quality control ; Shapley value ; processing ; thermosensing ; willingness to pay ; esophageal cancer ; cross-cultural affective test ; carryover effects ; Prunus dulcis ; hot beverages ; sensory acceptability ; mixed models ; chicken soup ; sensory bias ; product development ; temperature ; methodological study ; relative importance of attributes to liking ; product improvement ; nonlinear models ; consumer ; lexicon ; descriptive sensory analysis ; emulsification ; ingredient ; hydroSOStainable products ; temporal drivers of liking (TDOL) ; texture ; MSG substitutes ; functional data analysis ; food ; ethnic food ; descriptive analysis ; LMG statistic ; shelf life ; sensory evaluation ; sensory ; coffee ; fruit chews ; descriptive ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 62
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Food fermentation is one of the most ancient processes of food production that has historically been used to extend food shelf life and to enhance its organoleptic properties. However, several studies have demonstrated that fermentation is also able to increase the nutritional value and/or digestibility of food. Firstly, microorganisms are able to produce huge amounts of secondary metabolites with excellent health benefits and preservative properties (i.e., antimicrobial activity). Secondarily, fermented foods contain living organisms that contribute to the modulation of the host physiological balance, which constitutes an opportunity to enrich the diet with new bioactive molecules. Indeed, some microorganisms can increase the levels of numerous bioactive compounds (e.g., vitamins, antioxidant compounds, peptides, etc.). Moreover, recent advances in fermentation have focused on food by-products; in fact, they are a source of potentially bioactive compounds that, after fermentation, could be used as ingredients for nutraceuticals and functional food formulations. Because of that, understanding the benefits of food fermentation is a growing field of research in nutrition and food science. This book aims to present the current knowledge and research trends concerning the use of fermentation technologies as sustainable and GRAS processes for food and nutraceutical production.
    Keywords: QH301-705.5 ; QR1-502 ; Q1-390 ; chemical refining ; Lactic acid bacteria ; grapevine ; sourdough ; vegetable oil ; platelet-activating factor ; biogenic amines ; aglycones ; food fermentation ; food by-products ; beer ; Blakeslea trispora ; ?-aminobutyric acid (GABA) ; fish oil ; ?-glucosidase ; Thunnus thynnus ; lycopene ; histidine decarboxylase (hdc) gene ; fermentation ; wine ; ?-aminobutyric acid GABA ; thrombin ; isoflavones ; polar lipids ; phenolic compounds ; lactobacilli ; fatty acid profile ; antithrombotic ; UHPLC/ESI-QTRAP ; orange powder ; tyrosine decarboxylase (tdc) gene ; Sparus aurata ; amaranth flour ; soybean extract ; Penicillium citrinum ; indoleamines ; cardiovascular disease ; brewer’s spent grain ; Pecorino di Farindola ; liquid chromatography ; by-products ; lactic acid bacteria ; grains ; bioactive peptides ; Dicentrarhus labrax ; fungi ; raw milk ewe’s cheese ; ?-aminobutyric acid ; bioactive compounds ; hops ; volatile components ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 63
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Over the past decades, researchers have gathered data demonstrating that vitamin D and its metabolites possess activities far beyond the classic regulation of calcium–phosphate homeostasis. It is now well established that vitamin D is essential for the proper functioning of the musculoskeletal, cardiovascular, nervous, and immune systems. Furthermore, vitamin D and its analogs were shown to regulate proliferation and differentiation of keratinocyte, immune cells, and numerous cancer-derived cells, both in vivo and in vitro. On the other hand, population base studies have provided evidence that global vitamin D deficiency is correlated with the occurrence and aggravation of symptoms of skeletal, cardiovascular autoimmune, and skin disease; infections; metabolic and cognitive disorders; multiple types of cancers; as well as overall mortality. This Special Issue of International Journal of Molecular Sciences, entitled “Vitamin D and Human Health”, summarizes recent advances in our understanding of pleiotropic activity of vitamin D with a focus on its protective role against cancer, hypertension, viral infections, and neurological diseases, as well as its impact on the immune system and mitochondria. Furthermore, eight research papers provide new insight into vitamin D research and highlight new directions and targets in the prevention and treatment of human diseases.
    Keywords: QH301-705.5 ; Vitamin D ; supplementation ; extra-skeletal effects ; analogs of vitamin D ; therapy and prevention ; vitamin D deficiency ; vitamin D activity and metabolism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 64
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: It is now recognized that workplace aspects (scheduling, shift work, physically demanding work, chemical exposure) not only increase the risk of injury and illness, but also impact health behaviors (smoking, physical activity) and health outcomes (sleep disorders and fatigue, obesity, musculoskeletal disorders). In turn, ill health and chronic conditions can affect performance at work, increasing risk for injury, absenteeism, and reduced productivity. In the past few decades, programs that expand the traditional focus of occupational safety and health to consider nontraditional work-related sources of health and well-being have been shown to be more effective than programs that separately address these issues. This Total Worker Health approach has been recognized by the National Institute for Occupational Safety and Health (NIOSH) as a method for protecting the safety and health of workers, while also advancing the overall well-being of these workers by addressing work conditions. This compendium presents work from an international collection of scholars exploring the relationship between workplace factors and worker safety, health, and well-being. It provides guidance for improving the organization and design of work environments, innovative strategies for promoting worker well-being, and novel methods for exposing underlying occupational causes of chronic disease.
    Keywords: workplace bullying ; quality of life ; occupational health ; work-to-family conflict ; Korean workplaces ; organizational intervention ; health promotion ; injury prevention ; musculoskeletal ; ergonomics ; mixed-methods study ; construction industry ; safety management ; health risk behaviors ; workplace safety ; safety leadership ; health promoting leadership ; safety programs ; health protection ; leadership ; qualitative study ; Perceived Occupational Health (POH) ; Job Demands-Control-Social Support (JD-R) model ; professional accountants ; work organization ; dirty work ; moral leadership ; taint normalization ; management consulting ; burnout ; psychometric properties ; nursing ; workforce demographics ; home care workers ; workplace ; occupational ; safety ; health ; well-being ; dissemination ; cognitive demands ; employee well-being ; working conditions ; job satisfaction ; wellbeing ; wellbeing misalignment ; Millennials ; work stress ; productivity ; impairment cost ; stress management ; employee characteristics ; workplace health promotion ; health and safety ; cardiovascular disease ; work environment ; social capital ; trust ; Total Worker Health® ; health behaviors ; job stress ; occupational safety and health ; worker well-being ; turnover ; employment duration ; occupational injury ; manufacturing ; newly-hired workers ; occupational wellbeing ; performance ; happy-productive worker ; total worker health ; breastfeeding ; industry ; workplace accommodations ; work culture ; work policy ; occupational health surveillance ; young workers ; training ; MTurk ; likeability ; behavior change ; Total Worker Health ; participatory methods ; program implementation ; organizational readiness ; process evaluation ; logic model ; workplace health management ; occupational health and safety ; company reintegration management ; return to work ; cross-sectional survey ; Germany ; adolescent ; hypertension ; blood pressure ; Hispanic ; work ; farmworker ; integration ; participatory workplace program ; process fidelity ; program impact ; sustainability ; workplace health ; wellness ; governance ; planning ; barriers ; survey ; ACA ; precarious work ; action learning ; technical assistance ; community-university partnership ; policy, systems, and environmental (PSE) change ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 65
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Wearable electronics and embedded computing systems have been receiving a great deal of interest over the last two decades in research and commercial fields, with a special focus on biomedical applications. The key benefits introduced by these systems include their small size, lightweight, low-power consumption, and, of course, wearability. Major human-centered applications are related to medicine, enabling outpatient care and enhancing the quality of life for chronic disease patients, maybe preventing unnecessary hospitalization. These technological devices can indeed be cost effective and provide doctors with more accurate and reliable data. Exemplary engineering input has focused on developing innovative sensing platforms, adaptable to different environments and user needs, smart textile technology, miniaturized electronics and sensors, energy harvesting, wireless body area networks, and so on. This has provided the possibility of gathering information on several activities, such as during daily activities or sleep, during specific tasks, at home, in the lab, and in the clinic, in the form of physiological signals. This book includes cutting-edge research articles, as well as reviews describing and assessing wearable devices, or proposing novel wearable sensors, computational efficient algorithms for physiological signal processing through embedded computing, collection of environmental/behavioral/psychological data, data fusion, detection and quantification of symptoms, decision support for medical doctors, and communication between patient and doctor.
    Keywords: QH301-705.5 ; RC31-1245 ; QA1-939 ; electronics ; human-computer interaction ; haptics ; signal processing ; Wearable systems ; monitoring ; biomedical sensors ; biomedical signal ; physiological data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 66
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Dual specificity phosphatases (DUSPs) constitute a heterogeneous group of protein tyrosine phosphatases with the ability to dephosphorylate Ser/Thr and Tyr residues from proteins, as well as from other non-proteinaceous substrates including signaling lipids. DUSPs include, among others, MAP kinase (MAPK) phosphatases (MKPs) and small-size atypical DUSPs. MKPs are enzymes specialized in regulating the activity and subcellular location of MAPKs, whereas the function of small-size atypical DUSPs seems to be more diverse. DUSPs have emerged as key players in the regulation of cell growth, differentiation, stress response, and apoptosis. DUSPs regulate essential physiological processes, including immunity, neurobiology and metabolic homeostasis, and have been implicated in tumorigenesis, pathological inflammation and metabolic disorders. Accordingly, alterations in the expression or function of MKPs and small-size atypical DUSPs have consequences essential to human disease, making these enzymes potential biological markers and therapeutic targets. This Special Issue covers recent advances in the molecular mechanisms and biological functions of MKPs and small-size atypical DUSPs, and their relevance in human disease.
    Keywords: QH301-705.5 ; Q1-390 ; hematopoietic cells ; DEPArray ; n/a ; neuroblastoma ; liver steatosis ; MAPK phosphatase ; DUSP-4 ; granule neurons ; neuronal differentiation ; DUSP10 ; cytokines ; MAPKs ; single cell analysis ; macrophage ; asthma ; E. coli infection ; MAPK ; Cpp1 ; nucleotide receptors ; atypical DUSP ; RSV ; Pmp1 ; cannabinoids ; astrocytes ; sepsis ; influenza ; signaling ; triple-negative breast cancer (TNBC) ; differentiation ; HDAC6 (histone deacetylase isoform 6) ; atypical dual-specificity phosphatases ; microtubules ; respiratory viruses ; MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) ; dual-specificity phosphatase ; Msg5 ; TLR signaling ; mitogen-activated protein kinase ; fungal MKPs ; macrophages ; MAP Kinase Phosphatase-2 ; inflammation ; Sdp1 ; circulating tumor cells (CTCs) ; MAP kinases ; MAP kinase phosphatases ; P2X7 ; proliferation ; BDNF ; P2Y13 ; T cell ; hypertriglyceridemia ; integrated omics analysis ; post-translational modification ; rhinovirus ; protein stability ; ubiquitination ; dual-specificity phosphatases ; Mkp-1 ; cancer ; brain metastasis ; HER2 ; COPD ; pseudophosphatase ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 67
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Precision Medicine, understood as “the emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person” is currently one of the most talked about themes in biomedicine and great efforts are being made internationally to turn this concept into a reality. As the concept of Precision Medicine spreads, so too does that of “Precision Nutrition”, which would have to take individual variability into account when recommending personalized diets. Although huge progress has been made over recent years in research into the genotype in inter-individual responses to diet, proving that this heterogeneity does indeed exist, we still do not have top level scientific evidence to make the eagerly-awaited personalized dietary recommendations, either from the prevention or treatment of different diseases point of view. It is, therefore, essential to gather more information from studies which, from the nutrigenetic point of view, analyze gene–diet interactions in the different intermediate and final phenotypes of diseases. The ideal situation would be to have results available from randomized and controlled clinical trials. Results on gene–diet interactions obtained from large cohorts, and other types of studies with replication in independent samples, are also of great importance. Similarly, if nutrigenetic findings are accompanied by more mechanistic evidence, integrating other omics, this would be of particular interest. Lastly, another topic of interest is to share strategies for implementing genome-based nutritional interventions. Therefore, this Special Issue of Nutrients, “Nutrigenetics”, will focus on providing evidence of the inter-individual genetic effects of diet in determining diseases phenotypes. We are looking forward to receiving many submissions from outstanding experts on these topics. Experimental papers, meta-analyses, up-to-date review articles, and commentaries are all welcome.
    Keywords: QH301-705.5 ; Nutritional Genomics ; Precision Nutrition ; Nutrigenetics ; Gene–Diet Interactions ; Nutrigenomics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/png
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 68
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This Special Issue of International Journal of Molecular Sciences (IJMS) is dedicated to the mechanisms mediated at the molecular and cellular levels in response to adverse genomic perturbations and DNA replication stress. The relevant proteins and processes play paramount roles in nucleic acid transactions to maintain genomic stability and cellular homeostasis. A total of 18 articles are presented which encompass a broad range of highly relevant topics in genome biology. These include replication fork dynamics, DNA repair processes, DNA damage signaling and cell cycle control, cancer biology, epigenetics, cellular senescence, neurodegeneration, and aging. As Guest Editor for this IJMS Special Issue, I am very pleased to offer this collection of riveting articles centered on the theme of DNA replication stress. The blend of articles builds upon a theme that DNA damage has profound consequences for genomic stability and cellular homeostasis that affect tissue function, disease, cancer, and aging at multiple levels and through unique mechanisms. I thank the authors for their excellent contributions, which provide new insight into this fascinating and highly relevant area of genome biology.
    Keywords: QH301-705.5 ; Q1-390 ; Werner Syndrome ; n/a ; A549 cells ; epigenetic ; neurodegeneration ; Genome integrity ; adaptation ; cellular senescence ; genome instability ; Werner Syndrome Protein ; lipofuscin ; cell cycle checkpoints ; exonuclease 1 ; template-switching ; energy metabolism ; mutation frequency ; DNA replication ; fork regression ; motor neuron disease ; Microsatellites ; Alzheimer’s disease ; chromatin remodeler ; repair of DNA damage ; AP site analogue ; mutagens ; replication timing ; Thermococcus eurythermalis ; nucleolar stress ; gene expression ; mutations spectra ; origin firing ; Fanconi Anemia ; superfamily 2 ATPase ; DNA translocation ; DNA repair ; SSB signaling ; homologous recombination ; common fragile sites ; 8-chloro-adenosine ; replication ; genome stability ; mutagenicity ; fork reversal ; multiple sclerosis ; non-B DNA ; protein stability ; heterogeneity ; ubiquitin ; SenTraGorTM (GL13) ; replication restart ; EdU ; ?-arrestin ; NER ; aging ; SSB end resection ; oxidative stress ; ATR ; dormant origins ; R loops ; DNA damage response ; Difficult-to-Replicate Sequences ; DNA double-strand repair ; endonuclease IV ; ALS ; double strand break repair ; premature aging ; replication stress ; EXO1 ; POL? ; translesion synthesis ; strand displacements ; G2-arrest ; DNA replication pattern ; SSB repair ; genome integrity ; G protein-coupled receptor kinase interacting protein 2 (GIT2) ; MMR ; replicative stress ; senolytics ; spacer ; interactome ; ATR-Chk1 DDR pathway ; C9orf72 ; replication fork restart ; translesion DNA synthesis ; DNA damage ; mismatch repair ; DNA replication stress ; DNA helicase ; Polymerase kappa ; DNA fiber assay ; H1299 cells ; TLS ; APE2 ; ageing ; cell death ; chromosome ; TopBP1 ; barley ; clock proteins ; post-translational modification ; 8-oxoG ; S phase ; ataxia telangiectasia mutated (ATM) ; G protein-coupled receptor (GPCR) ; Polymerase eta ; cancer ; G protein-coupled receptor kinase (GRK) ; helicase ; genomic instability ; Parkinson’s disease ; nucleotide excision repair ; SupF ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 69
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Tissue engineering and regenerative medicine is a rapidly evolving research field which effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular populations using several tissue engineering approaches, such as the decellularization method. Indeed, the decellularization method aims to develop a cell-free biologic scaffold while keeping the extracellular matrix (ECM) intact. Furthermore, biologic scaffolds have been investigated for their in vitro potential for whole organ development. Currently, clinical products composed of decellularized matrices, such as pericardium, urinary bladder, small intestine, heart valves, nerve conduits, trachea, and vessels, are being evaluated for use in human clinical trials. Tissue engineering strategies require the interaction of biologic scaffolds with cellular populations. Among them, stem cells are characterized by unlimited cell division, self-renewal, and differentiation potential, distinguishing themselves as a frontline source for the repopulation of decellularized matrices and scaffolds. Under this scheme, stem cells can be isolated from patients, expanded under good manufacturing practices (GMPs), used for the repopulation of biologic scaffolds and, finally, returned to the patient. The interaction between scaffolds and stem cells is thought to be crucial for their infiltration, adhesion, and differentiation into specific cell types. In addition, biomedical devices such as bioreactors contribute to the uniform repopulation of scaffolds. Until now, remarkable efforts have been made by the scientific society in order to establish the proper repopulation conditions of decellularized matrices and scaffolds. However, parameters such as stem cell number, in vitro cultivation conditions, and specific growth media composition need further evaluation. The ultimate goal is the development of “artificial” tissues similar to native ones, which is achieved by properly combining stem cells and biologic scaffolds and thus bringing them one step closer to personalized medicine. The original research articles and comprehensive reviews in this Special Issue deal with the use of stem cells and biologic scaffolds that utilize state-of-the-art tissue engineering and regenerative medicine approaches.
    Keywords: QH301-705.5 ; Q1-390 ; nerve conduit ; tissue engineering ; regenerative medicine ; mixed lymphocyte reaction ; histological images ; future scaffold engineering ; multiparameter ; 3DPVS ; MSCs ; Wnt signaling ; Mesenchymal Stromal Cells ; factorial design ; novel scaffold ; Wharton’s Jelly tissue ; stem cells ; umbilical arteries ; SDS ; platelet rich plasma ; TGF? signaling ; traditional scaffold ; pluripotency and commitment ; tissue engineered construct ; HLA-G ; CHAPS ; platelets ; proteomic analysis ; vibrating nature of universe. ; VS55 ; cell culture ; FGF signaling ; evolution of scaffold ; dynamicity and dimensionality ; fibrin gel ; scaffold classification ; decellularization ; vitrification ; seven-folder logics ; IIEF-5 questionnaire ; TGF-?1 ; erectile dysfunction ; human induced pluripotent stem cells ; iPSCs ; scaffolds ; Barret’s esophagus ; nerve regeneration ; long term storage ; laws of system evolution ; scaffold categorization ; platelet lysate ; 3D scaffold ; esophagus ; language of relativity ; cord blood units ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 70
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging zoonotic coronavirus. First identified in 2012, MERS-CoV has caused over 2460 infections and a fatality rate of about 35% in humans. Similar to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV likely originated from bats; however, different from SARS-CoV, which potentially utilized palm civets as its intermediate hosts, MERS-CoV likely transmits to humans through dromedary camels. Animal models, such as humanized mice and nonhuman primates, have been developed for studying MERS-CoV infection. Currently, there are no vaccines and therapeutics approved for the prevention and treatment of MERS-CoV infection, although a number of them have been developed preclinically or tested clinically. This book covers one editorial and 16 articles (including seven review articles and nine original research papers) written by researchers working in the field of MERS-CoV. It describes the following three main aspects: (1) MERS-CoV epidemiology, transmission, and pathogenesis; (2) current progress on MERS-CoV animal models, vaccines, and therapeutics; and (3) challenges and future prospects for MERS-CoV research. Overall, this book will help researchers in the MERS-CoV field to further advance their work on the virus. It also has important implications for other coronaviruses as well as viruses outside the coronavirus family with pandemic potentials.
    Keywords: QH301-705.5 ; Q1-390 ; cell–cell fusion ; hDPP4 ; n/a ; therapeutics ; animal models ; HCoV-229E ; Drivers ; camels ; rabbits ; SARS-CoV ; MERS-CoV ; MVA vaccine ; transmission ; RBD ; MERS-CoV nucleocapsid protein ; complement ; animal model ; pseudotyped virus ; combination ; MERS-coronavirus ; peptide ; mouse model ; spike protein ; receptor-binding domain ; prevention and treatment ; coronaviruses ; coronavirus spike glycoprotein ; therapeutic antibodies ; vaccine platforms ; mutation ; severe acute respiratory syndrome coronavirus ; pathogenesis ; fusion inhibitor ; Coronavirus ; murine CD8+ T cell epitope ; lipidomics ; authentic virus ; correlates of immunity ; vaccines ; neutralizing monoclonal antibodies ; Middle East respiratory syndrome coronavirus ; small-molecule inhibitor ; Middle East Respiratory Syndrome Virus ; DPP4 ; pyroptosis ; cross-neutralization ; inflammation ; Qatar ; spike proteins ; One Health ; HKU4 ; nanobodies ; mechanism of action ; neutralizing antibody ; host factors ; UHPLC–MS ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 71
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Renal cancer is a health problem of major concern worldwide. Although tyrosine kinase inhibitors and immune check-point blockade treatments, alone or in combination, are giving promising results, failures are quite frequent due to intratumor heterogeneity and to the acquisition of drug resistance. The spectrum of renal cell carcinoma subtypes is wide. Up to 70–80% of renal tumors are clear cell renal cell carcinomas, a clinically aggressive tumor subtype linked to VHL gene inactivation. Next in frequency, the papillary renal cell carcinoma category encompasses an intricate puzzle of classic and newly described entities with poorly defined limits, some of them pending definite clarification. Likewise, the chromophobe–oncocytoma duality, the so-called hybrid tumors and oncocytic neoplasms, remain to be well profiled. Finally, a growing list of very uncommon renal tumors linked to specific molecular signatures fulfill the current portrait of renal cell neoplasia. This Special Issue of Cancers regards RCC from very different perspectives, from the intimate basic mechanisms governing this disease to the clinical practice principles of their diagnoses and treatments. The interested reader will have the opportunity to contact with some of the most recent findings and will be updated with excellent reviews.
    Keywords: QH301-705.5 ; Q1-390 ; N-glycomapping ; n/a ; SMAD proteins ; patient survival ; pro-IL-1? ; survival prediction ; inflammation markers ; tumor migration ; prognostic factors ; practical approach ; circular RNAs in a clinico-genomic predictive model ; glycomarkers ; review ; nephrectomy ; uric acid ; VEGF inhibitors ; metabolic reprogramming ; collecting duct carcinoma ; curcumin ; metabolome profiling ; identification of circular RNAs ; IL-2 ; experimental validation of circular RNA ; Raf/MEK/ERK ; HOT ; PI3K/Akt/mTOR ; pentose phosphate pathway ; kidney cancer ; LOT ; mutation ; RCC ; polybromo-1 ; pale cell ; MMP-9 ; gene expression ; recurrence free survival ; chromosomal loss ; IL-1? ; chronic kidney disease ; glutathione transferase omega 2 ; label-free ; glutathione transferase omega 1 ; emerging entity ; copy number alteration ; FOXO3 ; predictive role ; tumor slice culture ; tyrosine kinase inhibitors ; PPP ; ESC ; CDKN1A expression ; metastasis ; PD-L1 ; diagnostic and prognostic markers ; EVI1 ; copy number loss ; RNA sequencing ; NK cells ; glutathione metabolism ; clear cell renal cell carcinoma ; renal cell cancer ; proliferation ; eosinophilic variant ; Xp11 translocation renal cell carcinoma ; prognosis ; invasion ; immune infiltration ; IL4R? ; FISH ; 11) translocation renal cell carcinoma ; tumor microenvironment ; metabolome ; hyperosmolality ; toxicity ; ALK ; drug sensitivity ; t(6 ; copy number analysis ; urine ; genetic association ; polymorphism ; solute carrier proteins ; kidney ; metastatic ccRCC ; molecular genetic features ; recurrence-free survival ; chromophobe renal cell carcinoma ; unclassified renal tumor ; overall survival ; mTOR inhibitors ; mTOR ; JAK2 ; von Hippel–Lindau ; miR-155-5p ; glycoproteomics ; PBRM1 ; miR-133b ; survival ; TFE3 ; TFEB ; oncocytic renal tumor ; immune checkpoint inhibitors ; biomarker ; MMP10 ; TCGA ; ghrelin ; EMT like ; checkpoint inhibitors ; MiT family translocation renal cell carcinoma ; gene signature ; sarcomatoid ; transforming growth factor beta ; clear cell Renal Cell Carcinoma ; tumor adhesion ; renal cancer ; unclassified renal cell carcinoma ; Papillary renal cell carcinoma (pRCC) ; miR-146a-5p ; renal cell ; everolimus ; integrins ; cytoreductive nephrectomy ; immunotherapy ; predictive factors ; immunohistochemistry ; MTA2 ; IL13R?1 ; targeted therapy ; intratumour heterogeneity ; aurora A ; TCA cycle ; AMP-activated protein kinases ; cancer-specific survival ; programmed death-ligand 1 ; efficacy ; renal cell carcinoma ; anaplastic lymphoma kinase rearrangement ; TFEB-amplified renal cell carcinoma ; statins ; cancer immunotherapy ; microRNA ; new entity ; proteome profiling ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 72
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Salt stress is one of the most damaging abiotic stresses because most crop plants are susceptible to salinity to different degrees. According to the FAO, about 800 million Has of land are affected by salinity worldwide. Unfortunately, this situation will worsen in the context of climate change, where there will be an overall increase in temperature and a decrease in average annual rainfall worldwide. This Special Issue presents different research works and reviews on the response of plants to salinity, focused from different points of view: physiological, biochemical, and molecular levels. Although an important part of the studies on the response to salinity have been carried out with Arabidopsis plants, the use of other species with agronomic interest is also notable, including woody plants. Most of the conducted studies in this Special Issue were focused on the identification and characterization of candidate genes for salt tolerance in higher plants. This identification would provide valuable information about the molecular and genetic mechanisms involved in the salt tolerance response, and it also supplies important resources to breeding programs for salt tolerance in plants.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; soluble nutrients ; transcription factor ; n/a ; CDPK ; salicylic acid ; antioxidant enzymes ; light saturation point ; phytohormone ; ion homeostasis ; antioxidant systems ; photosynthesis ; Chlamydomonas reinhardtii ; high salinity ; nitric oxide ; poplars (Populus) ; root activity ; abiotic stresses ; transcriptional activator ; germination ; ABA ; transcriptome ; mandelonitrile ; redox homeostasis ; association mapping. ; redox signalling ; osmotic stress ; flax ; strigolactones ; salt tolerance ; nucleolin ; CaDHN5 ; photosystem ; EST-SSR ; NMT ; Sapium sebiferum ; Gossypium arboretum ; SOS ; Brassica napus ; SnRK2 ; HKT1 ; grapevine ; transcription factors ; cucumber ; underpinnings of salt stress responses ; abiotic stress ; Arabidopsis thaliana ; RNA-seq ; halophytes ; single nucleotide polymorphisms ; dehydrin ; J8-1 plum line ; chlorophyll fluorescence ; natural variation ; hydrogen peroxide ; salt stress ; lipid peroxidation ; ROS detoxification ; ROP ; molecular mechanisms ; cell membrane injury ; booting stage ; ascorbate cycle ; banana (Musa acuminata L.) ; iTRAQ quantification ; ROS ; Na+ ; Capsicum annuum L. ; bZIP transcription factors ; multiple bioactive constituents ; NaCl stress ; physiological changes ; VOZ ; transcriptional regulation ; genome-wide identification ; Apocyni Veneti Folium ; impairment of photosynthesis ; salt-stress ; Oryza sativa ; reactive oxygen species ; lipid accumulation ; polyamines ; multivariate statistical analysis ; DEUs ; salinity ; TGase ; Salt stress ; Prunus domestica ; proteomics ; Arabidopsis ; RNA binding protein ; rice ; glycophytes ; SsMAX2 ; drought ; genome-wide association study ; transcriptome analysis ; signal pathway ; melatonin ; MaROP5g ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 73
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Mathematical and computational modeling approaches in biological and medical research are experiencing rapid growth globally. This Special Issue Book intends to scratch the surface of this exciting phenomenon. The subject areas covered involve general mathematical methods and their applications in biology and medicine, with an emphasis on work related to mathematical and computational modeling of the complex dynamics observed in biological and medical research. Fourteen rigorously reviewed papers were included in this Special Issue. These papers cover several timely topics relating to classical population biology, fundamental biology, and modern medicine. While the authors of these papers dealt with very different modeling questions, they were all motivated by specific applications in biology and medicine and employed innovative mathematical and computational methods to study the complex dynamics of their models. We hope that these papers detail case studies that will inspire many additional mathematical modeling efforts in biology and medicine
    Keywords: QH301-705.5 ; Q1-390 ; predator-prey model ; n/a ; uncertainty quantification ; identification of DNA-binding proteins ; chemostat ; numerical characterization ; differential equations ; uniform persistence ; spotting ; 2-combination ; wildfire ; chronic myeloid leukemia ; combination therapy ; liquid-solid-porous media seepage coupling ; dynamic model ; obesity ; epidermis ; articular cartilage ; androgen deprivation therapy ; quorum sensing ; mechano-electrochemical model ; bifurcations ; bacterial competition ; global stability ; cartilage degeneration ; flocculation ; dynamical system ; transport equations ; bootstrapping ; stationary distribution ; algae growth models ; hemodynamic model ; delay ; Raphidocelis subcapitata ; cartilage loading ; Daphnia magna ; cell-based vector ; switched harvest ; hepatitis B ; rich dynamics ; spotting distribution ; asymptotic theory ; tyrosine kinase inhibitors ; phylogenetic analysis ; immune response ; microcirculation load ; graphical representation ; intraguild predation ; numerical simulation ; bacterial inflammation ; data fitting ; immunomodulatory therapies ; drug therapy ; delay differential equations (DDE) ; global asymptotic stability ; model comparison tests ; optimal control ; generalized pseudo amino acid composition ; random perturbations ; limit cycle ; prostate cancer ; mathematical model ; mathematical modeling ; persistence ; equilibrium points ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 74
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The year 2019 has been prolific in terms of new evidence regarding the effects of coffee and caffeine consumption on diverse aspects of human functioning. This book collects 20 high-quality manuscripts published in Nutrients that include original investigation or systematic review studies of the effects of caffeine intake on human performance and health. The diversity of the articles published in this Special Issue highlights the extent of the effects of coffee and caffeine on human functioning, while underpinning the positive nature of most of these effects. This book will help with understanding why the natural sources of caffeine are so widely present in the nutrition behaviors of modern society.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; NAT ; n/a ; supplementation ; EEG–EMG coherence ; muscle function ; tea ; fatigue ; ergogenic ; adrenal gland ; skeletal muscle ; xanthine oxidase ; placebo ; CMJ ; efficiency ; colorectal cancer ; rat ; pregnancy ; coffee/caffeine ; Wingate ; 1RM test ; supplement ; actigraphy ; athletic ; systematic review and meta-analysis ; women ; consumption motives ; resistance training ; cancer prevention ; sport supplement ; exercise ; DOMS ; placebo effect ; sprint performance ; power ; behavior ; belief ; health ; perceptions ; exercise performance ; ergogenic aid ; electromyography ; ergogenic effect ; corticosterone ; metabolome ; mood state ; muscle contraction ; strength ; energy drink ; repetition ; responders ; perception ; anaerobic ; CYP450 ; puberty ; energy drinks ; isokinetic testing ; individual responses ; phenotyping ; nutrition ; time under tension ; menstrual cycle ; exercise training ; RPE ; ergogenic substances ; upper limb ; elite athlete ; recovery ; speed ; epidemiology ; caffeine ; sex-difference ; bench press ; pharmacokinetics ; sport performance ; ergogenic aids ; expectancy ; consumer ; football ; newborn ; velocity ; metabolites ; performance ; coffee ; prospective studies ; resistance exercise ; sport ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 75
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Nowadays, one of the main objectives of the fruit and vegetable industry is to develop innovative novel products with high quality, safety, and optimal nutritional characteristics in order to respond, with efficiency, to increasing consumer expectations. Various unconventional technologies (e.g., pulsed electric field, pulsed light, ultrasound, high pressure, and microwave drying) have emerged and enable the processing of fruits and vegetables in a way that increases their stability while preserving their thermolabile nutrients, flavour, texture, and overall quality. Some of these technologies can also be used for waste and byproduct valorisation. The application of fast noninvasive methods for process control is of great importance for the fruit and vegetable industry. The following Special Issue “Safety, Quality, and Processing of Fruits and Vegetables” consists of 11 papers which represent a high-value contribution to the existing knowledge on safety aspects, quality evaluation, and emerging processing technologies for fruits and vegetables.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; blanching ; valorization ; dielectric spectroscopy ; antioxidant activity ; postharvest physiology ; eco-extraction ; thermal properties ; cranberries ; safety ; healthy food ; reducing sugar ; pulsed electric field ; dehydration ; high voltage electrical discharge ; fluence ; sonication ; raspberry ; permittivity ; unconventional processing ; pectin methyl esterase ; isotherms ; extraction ; sucrose ; sustainability ; mango juice ; quality ; lycopene ; hot air drying ; waste reduction ; birefringence ; processing ; thermo-sonication ; green solvents ; sustainable production ; emerging technologies ; reduced pressure ; color ; fruit ; ultra-high pressure ; phenolic compounds ; pulsed electric fields ; tomato ; vegetable ; chip processing ; vegetables ; olive leaves extracts ; red beet ; enzyme susceptibility ; cold storage ; potato ; potato starch ; freeze-drying ; pulsed light ; reconditioning ; candying ; non-thermal treatment ; convective drying ; color change ; texture ; physicochemical property ; gallic acid ; high pressure ; bioactive compounds ; microscopy ; shrinkage ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 76
    Publication Date: 2024-04-05
    Description: ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. This special issue of the International Journal of Molecular Sciences contains a collection of articles by colleagues of Antonius (Ton) Gerardus Rolink (19/04/1953-06/08/2017) and honors Ton’s life and profound knowledge of and huge contribution to science. Ton participated in an FP7 Marie Curie Initial Training Network called DECIDE, and partners have submitted articles for this Special Issue. Scientists outside this network have also submitted articles. The articles examine various aspects of how the hematopoietic stem-cell gives rise to the different types of blood and immune cells. These include decision-making by the hematopoietic stem cell and the importance of controlling events within cells and the niches the cell resides in. New insights into these processes at the basic scientific level have given rise to an emerging new model for the development of blood cells. In turn, changes to our understanding of this process have led to new and exciting propositions regarding what goes wrong during the early stages of the development of leukemia.
    Keywords: QH301-705.5 ; RC254-282 ; stem cells ; cell differentiation ; leukaemia ; haematopoiesis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 77
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: In recent years, the advances and abilities of computer software have substantially increased the number of scientific publications that seek to introduce new probabilistic modelling frameworks, including continuous and discrete approaches, and univariate and multivariate models. Many of these theoretical and applied statistical works are related to distributions that try to break the symmetry of the normal distribution and other similar symmetric models, mainly using Azzalini's scheme. This strategy uses a symmetric distribution as a baseline case, then an extra parameter is added to the parent model to control the skewness of the new family of probability distributions. The most widespread and popular model is the one based on the normal distribution that produces the skewed normal distribution. In this Special Issue on symmetric and asymmetric distributions, works related to this topic are presented, as well as theoretical and applied proposals that have connections with and implications for this topic. Immediate applications of this line of work include different scenarios such as economics, environmental sciences, biometrics, engineering, health, etc. This Special Issue comprises nine works that follow this methodology derived using a simple process while retaining the rigor that the subject deserves. Readers of this Issue will surely find future lines of work that will enable them to achieve fruitful research results.
    Keywords: positive and negative skewness ; ordering ; fitting distributions ; Epsilon-skew-Normal ; Epsilon-skew-Cauchy ; bivariate densities ; generalized Cauchy distributions ; asymmetric bimodal distribution ; bimodal ; maximum likelihood ; slashed half-normal distribution ; kurtosis ; likelihood ; EM algorithm ; flexible skew-normal distribution ; skew Birnbaum–Saunders distribution ; bimodality ; maximum likelihood estimation ; Fisher information matrix ; maximum likelihood estimates ; type I and II censoring ; skewness coefficient ; Weibull censored data ; truncation ; half-normal distribution ; probabilistic distribution class ; normal distribution ; identifiability ; moments ; power-normal distribution ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 78
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Inequity starts before birth and is programmed in part by nutritional exposures. If these exposures occur around the time of conception, during pregnancy, and/or in infancy or childhood (all critical periods of development) they may alter a child’s health trajectory and impact risk for impaired cognition and learning, and cardiometabolic, immune, and neuropsychiatric diseases and disorders. This Special Issue on “Early Life Nutrition and Future Health” has the following aims: 1) understand the origins of offspring health inequities from an early nutritional perspective; 2) uncover new insights into the environmental, biological, and social mechanisms that underpin these health outcomes in offspring; and 3) present novel targets and approaches to optimise health trajectories and prevent chronic diseases and disorders in later life and across generations. The research projects included herein highlight novel mechanistic, epidemiologic, and intervention studies that target key windows where nutrition has the greatest influence on future health (preconception, prenatal, and postnatal periods) and that explore vulnerable populations and animal models of early life nutritional programming.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; gut-brain ; life-course epidemiology ; milk composition ; postnatal calcium homeostasis ; fruit juices ; phospholipids ; infant ; abdominal obesity ; postpartum ; L-cell ; programming ; gut health ; development ; sugars ; pregnancy ; gangliosides ; non-communicable disease ; prebiotic ; dietary reference intakes (DRIs) ; adulthood ; adult bone health ; malnutrition ; supplements ; nutrition ; dietary fibre ; gut barrier ; child ; microbiota ; folic acid supplementation ; Healthy Eating Index ; human milk ; nutrient-sensing signal ; fetal ; epidemiology ; developmental origins of health and disease (DOHaD) ; dietary intake ; pH ; energy intake ; human milk oligosaccharides ; undernutrition ; short-chain fatty acid (SCFA) ; LC–MS ; eating behavior ; gut microbiota ; reprogramming ; social inequalities ; diet quality ; reduced litter size ; sphingomyelin ; oxidative stress ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 79
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: This volume explores the intersections of religion, power, and resistance in a fast-changing world. The authors herein seek to disrupt the sociology of religion’s dominant paradigms, especially its overemphasis in Europe and the United States, as well as its preference for official religions as opposed to diverse worldviews in all of their manifestations from around the world: Africa, Asia, Australia, Europe, the Middle East, and North and South America. The papers in this volume explore ways of decentering the Global North and of decolonizing the sociology of religion’s core concepts. They explore strategies used by newer and popular forms of religion to challenge existing power structures. Moreover, they examine the intersectionalities that privilege some people’s religious lives and disprivilege others. They show how religion, spirituality, and non-religion are much more complex than the dominant paradigms have led us to believe. This volume seeks to generate robust discussion and critical reflection on new ideas for a divided world, thus contributing to the advancement of the discipline of religious sociology.
    Keywords: sociology of religion ; post-colonial ; reflexivity ; epistemology ; race ; religion ; violence ; South Africa ; decoloniality ; Chinese religion ; secularization ; Xunzi ; Durkheim ; identity ; African Pentecostalism ; integration ; transnationalism ; diaspora ; religious diversity ; religions ; law ; media ; education ; religious strength ; sex ; gender ; Canada ; religion and migration ; intersectionality ; popular religions ; multiple modernities ; lived religion ; power ; resistance ; social theory ; holistic spirituality ; Ghana’s New Churches ; ideology ; dominant ideology ; alternative ideology ; political power ; social constructionism ; Islamism ; Islam ; Shi’ism ; spiritualism ; rituals ; Iran ; non-religion ; atheism ; persecution ; policy ; diversity ; young people ; spirituality ; complexity ; hybridity ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 80
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Nutrients is planning a Special Issue focusing on beverages and ingestive behavior. This Special Issue will focus on research related to all aspects of beverage consumption and post-ingestive consequences. There continues to be much controversy surrounding the influence of beverage choice on health outcomes. Research investigating the impact of beverage choice has on human health and post-ingestive consequences continue to grow. We know from the growing body of literature that beverage choice has a substantial impact on metabolism, food reinforcement and eating behaviors.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; toddlers ; yogurt ; satiety ; ad libitum buffet ; Balearic Islands ; gastric emptying ; epigenetics ; nutrition education ; mothers ; Repertory Grid Technique ; children ; (conjugated) plant sterols ; lipoprotein-oxidation ; beta-casein ; obesity ; whey protein ; beverages ; Laddering Technique ; casein ; intention ; fermented-beverage ; preschoolers ; water consumption ; planned behavior ; health claims ; parents ; total water intake ; non-nutritive sweeteners ; adults ; total energy intake ; visual food cues ; health promotion ; self-determination ; endothelial-function ; anti-carcinogenic ; anti-aging ; cardiovascular-risk-factors ; sweet taste ; sugar sweetened beverages ; cows’ milk ; cholesterol-lowering ; anti-inflammatory ; sugar-sweetened beverages ; overweight ; gain- and loss-framed messages ; in vitro digestion ; gamma-scintigraphy ; electroencephalography ; beverage consumption ; type 1 diabetes ; social cognitive theory ; ergosterol ; parenting practices ; qualitative methods ; cholesterol-efflux ; coronary heart disease ; HDL-antioxidant-capacity ; Australia ; NOD mice ; sport ; food intake ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 81
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Networks of coordinated interactions among biological entities govern a myriad of biological functions that span a wide range of both length and time scales—from ecosystems to individual cells and from years to milliseconds. For these networks, the concept “the whole is greater than the sum of its parts” applies as a norm rather than an exception. Meanwhile, continued advances in molecular biology and high-throughput technology have enabled a broad and systematic interrogation of whole-cell networks, allowing the investigation of biological processes and functions at unprecedented breadth and resolution—even down to the single-cell level. The explosion of biological data, especially molecular-level intracellular data, necessitates new paradigms for unraveling the complexity of biological networks and for understanding how biological functions emerge from such networks. These paradigms introduce new challenges related to the analysis of networks in which quantitative approaches such as machine learning and mathematical modeling play an indispensable role. The Special Issue on “Biological Networks” showcases advances in the development and application of in silico network modeling and analysis of biological systems.
    Keywords: QH301-705.5 ; TA1-2040 ; RC109-216 ; Pathway crosstalk ; Alzheimer’s disease ; Bioenergy crops ; Model identification ; Metabolic networks ; Host–pathogen interactions ; Single cell ; Parameter sensitivity ; Tuberculosis ; Multivariate statistical analysis ; Systems biology ; Biological networks ; Mathematical modeling ; Lignin biosynthesis ; Design of experiments ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 82
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Yeasts are truly fascinating microorganisms. Due to their diverse and dynamic activities, they have been used for the production of many interesting products, such as beer, wine, bread, biofuels, and biopharmaceuticals. Saccharomyces cerevisiae (brewers’ or bakers’ yeast) is the yeast species that is surely the most exploited by humans. Saccharomyces is a top-choice organism for industrial applications, although its use for producing beer dates back to at least the 6th millennium BC. Bakers’ yeast has been a cornerstone of modern biotechnology, enabling the development of efficient production processes. Today, diverse yeast species are explored for industrial applications. This Special Issue “Yeast Biotechnology 2.0” is a continuation of the first Special Issue, “Yeast Biotechnology” (https://www.mdpi.com/books/pdfview/book/324). It compiles the current state-of-the-art of research and technology in the area of “yeast biotechnology” and highlights prominent current research directions in the fields of yeast synthetic biology and strain engineering, new developments in efficient biomolecule production, fermented beverages (beer, wine, and honey fermentation), and yeast nanobiotechnology.]
    Keywords: QH301-705.5 ; TP248.13-248.65 ; bioethanol production ; mead ; nanobiotechnology ; fermentation-derived products ; flavor ; citric acid production ; enzyme production ; non-Saccharomyces yeasts ; fermented beverages ; bioreactors ; Saccharomyces cerevisiae ; wine ; beer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 83
    Publication Date: 2024-04-05
    Description: The role of soils for achieving the Sustainable Development Goals is multifarious. Soils are the essential basis for food and biomass provision in support of food security (SDG 2) and energy security (SDG 7). Soil carbon sequestration is paramount for climate action (SDG 13). Soil-mediated water purification and retention, nutrient and matter cycling, and soils habitat functions are essential for maintaining ecosystem services and biodiversity (SDG 15). Healthy soils perform well in all these functions simultaneously. However, the globally increasing demand for food, fiber, and bio-based products poses massive challenges to soil health. Minimizing trade-offs between biomass production and soil health requires systemic approaches to assessment and governance of sustainable soil management in agriculture and food systems. It provides interdisciplinary insights into key questions: What are the impacts of agricultural management practices on sustainability targets in specific geophysical and socio-economic contexts? What are the opportunities and risks of future trends such as climate change, digitalization, and emerging technologies for soil management and soil health? How can institutions and governance instruments be improved to enable decision makers to take action on sustainable soil management? The book was initiated in the frame of the National German research program ‘BonaRes—Soil as a sustainable resource for the bioeconomy’, and it is meant to trigger interdisciplinary thinking.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; land management ; risk assessment ; carob ; N leaching ; Syria ; earthworms ; subsoil ; desertification ; alfalfa ; yield potential ; tenant ; dynamic programming ; soil policy ; monitoring ; resource scarcity ; soil management ; crop–livestock interactions ; German Constitutional Law ; gross income ; Germany ; spatially explicit ; creation ethics ; bayesian network ; agricultural practices ; conventional farming ; soil ; soil degradation ; combination of modern and indigenous knowledge ; Costa Rica ; yield ; soils ; rent price ; fertilization ; sustainability assessment ; societal acceptance ; property rights ; justifying soil protection ; subsoil loosening ; behavioural studies ; governance ; agricultural policy ; water infiltration ; sealing ; soil protection ; soil framework directive ; rent proportion ; soil remediation ; so-called organic fertilizer ; soil compaction ; nutrient composition ; phosphorus ; resource use efficiency ; soil pressures ; soil threats ; Europe ; soil functions ; literature review ; sustainability ; conservation agriculture ; institutions ; environmental zones ; soil health ; landowner ; soil governance ; zero tillage ; coffee by-products ; production ; arid oasis ; Laudato si’ ; soil food web ; land ; compaction ; farmer motivations ; agricultural innovation ; crop rotation modelling ; Driver-Pressure-State-Impact-Response sustainability framework ; contamination ; sustainable soil management ; agricultural yields ; Nicaragua ; sustainable agriculture ; ecosystem services ; legal comparison ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 84
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This book presents cross-discipline studies covering aspects ranging from animal science to social/consumer sciences and psychology, with the aim to collect and disseminate information promoting the continuous enhancement of animal welfare by improving stakeholders’ perception of animal welfare. Although animal welfare is about how the animals perceive the surrounding environment, the actual welfare of the animals is dependent on how the stakeholders perceive and weigh animal welfare. The stakeholders can, either directly (i.e., through stock-people interaction with the animals) or indirectly (e.g., when retailers and consumers are willing to pay more for high welfare animal-based products), affect the way animals are kept and handled.
    Keywords: QH301-705.5 ; SF1-1100 ; Q1-390 ; education ; animal welfare ; young adult ; welfare ; stunning ; human health ; perception ; slaughter ; pig ; pigs ; children ; livestock ; laying hen ; racehorse welfare ; qualitative research ; free elicitation narrative interviews ; knowledge ; fear ; milk production ; ethical concerns ; food safety concerns ; agreement ; stakeholder perception ; castration ; sheep farmers ; farmer perception ; animal ethics ; goat ; benefit ; horse ; dairy buffalo ; animal attitudes ; turkey ; farm animal welfare (FAW) ; animal ; survey ; Animal welfare ; husbandry practices ; willingness to pay ; donkey ; avoidance distance ; training ; stockperson behaviour ; stockpeople attitudes ; farm animal welfare ; farm animals ; veterinary students ; broiler ; text mining ; religious slaughter ; profit ; consumer ; sheep ; egg farm ; Halal meat ; pain ; employee relations ; standards of care ; animal behavior ; consumer demand ; albumen corticosterone ; aggression ; technology ; transport ; test-retest reliability ; desensitization ; producer perspective ; economics ; pain perception ; Asia ; horse–human relationship ; lambs ; veterinary student ; human-animal relationship ; information ; citizen perception ; immunocastration ; perceived consumer effectiveness ; staff shortages ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 85
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Spruce budworm (Choristoneura fumiferana (Clem.)) outbreaks are a dominant natural disturbance in the forests of Canada and northeastern USA. Widespread, severe defoliation by this native insect results in large-scale mortality and growth reductions of spruce (Picea sp.) and balsam fir (Abies balsamea (L.) Mill.) forests, and largely determines future age–class structure and productivity. The last major spruce budworm outbreak defoliated over 58 million hectares in the 1970s–1980s, and caused 32–43 million m3/year of timber volume losses from 1978 to 1987, in Canada. Management to deal with spruce budworm outbreaks has emphasized forest protection, spraying registered insecticides to prevent defoliation and keep trees alive. Other tactics can include salvage harvesting, altering harvest schedules to remove the most susceptible stands, or reducing future susceptibility by planting or thinning. Chemical insecticides are no longer used, and protection strategies use biological insecticides Bacillus thuringiensis (B.t.) or tebufenozide, a specific insect growth regulator. Over the last five years, a $30 million research project has tested another possible management tactic, termed an ‘early intervention strategy’, aimed at area-wide management of spruce budworm populations. This includes intensive monitoring to detect ‘hot spots’ of rising budworm populations before defoliation occurs, targeted insecticide treatment to prevent spread, and detailed research into target and non-target insect effects. The objective of this Special Issue is to compile the most recent research on protection strategies against spruce budworm. A series of papers will describe results and prospects for the use of an early intervention strategy in spruce budworm and other insect management.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; pheromone mating disruption ; spruce budworm ; insecticide application ; multi-spectral remote sensing ; simulation ; apparent fecundity ; Choristoneura fumiferana (Clemens) ; Pinaceae ; Choristoneura fumiferana ; circadian rhythm ; forest protection ; early intervention strategy ; insect population management ; moth ; survival ; Phialocephala scopiformis ; moths ; optimized treatment design ; spatial-temporal patterns ; monitoring ; modelling ; science communication ; decision support system ; population control ; area-wide management ; tortricidae ; insect susceptibility ; egg recruitment ; annual defoliation ; treatment threshold ; Maine ; dispersal ; growth rate ; forest pests ; Choristoneura fumiferana (Clem.) ; mixed effect models ; intertree variance ; endophytic fungi ; Acadian region ; insecticides ; defoliation ; Abies balsamea ; Picea glauca ; immigration ; defoliation prediction ; early intervention ; Quebec ; phenology ; aerobiology ; economic losses ; spatial autocorrelation ; foliage protection ; computable general equilibrium model ; economic and ecological cost: benefit analyses ; hardwood content ; plant tolerance ; Lepidoptera ; migration ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 86
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: There is general agreement within the fields of food, nutrition, and medical sciences that an individual’s diet and lifestyle can substantially predispose one to, or protect against osteoporosis, low bone mass, and numerous other age-related bone diseases. Dietary bioactives, found diversity in a variety of foods from fruits to vegetables, herbs and spices, essential oils and beverages, have the potential to influence bone health. The NIH Office of Dietary Supplements has defined dietary bioactives as “compounds that are constituents in foods and dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status.” These compounds are generally thought to be safe in food at normal consumption levels (e.g., polyphenols in plant foods). Dietary bioactives are currently being assessed for their properties beyond antioxidant capacity, including anti-inflammatory actions. Some compounds or classes of compounds have been reported to enhance bone formation and inhibit bone resorption through their actions on cell signaling pathways that influence osteoblast and osteoclast differentiation. Emerging scientific evidence is available, including observational studies and small clinical interventions that suggest consumption of certain dietary bioactives may have beneficial effects on bone health. Animal models have the unique advantage of feeding controlled diets for extended periods of time to assess long-term changes in bone. While bone mineral density (BMD) is the gold standard for assessing fracture risk, other factors such as bone structure, including trabecular thickness and separation, influence bone strength. Bone turnover rate is also predictive of fracture. Future research is needed to determine the types and quantities of dietary bioactives that are most effective and at what dose, as well as the mechanisms involved in modulating cellular events, in order to set precedence for larger clinical trials.
    Keywords: QH301-705.5 ; bioactives ; dietary ; bone ; osteoporosis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/png
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 87
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The purpose of this Special Issue is to provide a thorough and up-to-date presentation of research investigating the impact of coffee and/or caffeine intake on various health outcomes. Areas of interest include, but are not limited to, the following topics: Human clinical trials of coffee or caffeine use in relation to disease or intermediate phenotypes. Epidemiological studies of habitual coffee or caffeine intake in relation to human health, among the general public, as well as, among special populations (i.e., children, pregnant women, diabetics, cancer patients, hypertensives, etc.). Mechanisms of action of nutrients and other bioactive components of coffee/caffeine. Studies integrating genetic or physiological markers of coffee/caffeine intake to investigations of coffee and health.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; coronary artery disease ; n/a ; lipids ; NADH dehydrogenase ; tea ; tinnitus ; safety ; transcriptomics ; ergogenic ; guidelines ; myocardial perfusion ; placebo ; Caffeine ; risk factors ; lysophosphatidylcholine ; pregnancy ; assisted reproduction techniques ; population ; adenosine ; liver fibrosis ; coffee consumption ; cognitive ; causation ; supplement ; mate ; adult ; gene expression ; wine ; lipidomics ; chocolate ; exercise ; protection ; Suicide ; dipyridamole ; regadenoson ; live birth ; hearing ; pharmacological ergogenic aid ; behavior ; cardiovascular disease ; gene-diet interaction ; whole-blood ; sex ; health ; systematic review ; causality ; genetic epidemiology ; implantation ; pharmacogenomics ; cognitions ; ergogenic aid ; time trial performance ; CYP1A2 ; aging ; phenolic ; country ; caffeine intake ; serum chloride levels ; polymorphism ; responders ; intoxication ; trial ; epidemiological methods ; bias ; adenosine receptor ; longevity ; did not respond ; energy drinks ; biomarkers ; individual responses ; Mendelian Randomization ; public policy ; anxiety ; the Norwegian Women and Cancer Cohort (NOWAC) ; ADORA2A ; clinical pregnancy ; caffeine metabolism ; caffeine intoxication ; cohort study ; mood ; mRNA ; alcohol consumption ; epidemiology ; caffeine ; expectancy ; accidental death ; European Prospective Investigation into Cancer and Nutrition ; cognition ; consumption ; HIV-HCV co-infection ; cytochrome P450 ; chlorogenic acids ; soda ; 24-h dietary recall ; coffee ; depression ; sport ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 88
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The aim of this Special Issue is to review, understand, and evaluate new and exciting opportunities from the field on regenerative medicine, biomaterials, and stem cell research for the bioengineering of human liver grafts that can be applied for transplantation and personalized treatment of end-stage liver disease.The development of culture conditions for long-term expansion of LGR5+ intestinal stem cells as crypt-villus structures demonstrated the feasibility of deriving complex, organ-like structures in vitro from primary adult tissues, including the liver. Moreover, human pluripotent stem cells (hPSCs) can be applied to generate functionally maturated liver and bile duct epithelial cells.In this Special Issue, we welcome reviews and original papers focussing on hepatic cell sources, including adult hepatic stem cells, organoids, fetal and induced pluripotent stem cells, and primary cells (i.e., hepatocytes, cholangiocytes, and endothelial cells) and how these cells can be applied in tissue engineering strategies to generate implantable and personalized liver grafts. Potential topics include, but are not limited to, the following: liver tissue engineering, liver regeneration, graft repair, liver stem cells and organoids, bio-scaffolds, and 3D printing.We invite you to contribute original research papers, as well as comprehensive reviews, aligned with these themes, to advance and improve the actual state-of-the-art in liver bioengineering and providing new opportunities for the imminent medical problem of organ and tissue shortage for transplantation.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; tissue engineering ; regenerative medicine ; liver tissue bioengineering ; additive manufacturing ; copper toxicosis ; hepatobiliary stent ; reconditioning ; medical device ; liver regeneration ; Wilson Disease ; stem cells ; preclinical large animal model ; liver ; stem cell transplantation ; liver bioreactors ; personalized medicine ; direct printing ; hydrogel ; 3D structuring ; oxygen persufflation ; end-stage liver diseases ; 3D printing ; liver transplantation ; bioengineered organ ; randomized controlled trail ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 89
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Starting from a kinase of interest, AMP-activated protein kinase (AMPK) has gone far beyond an average biomolecule. Being expressed in all mammalian cell types and probably having a counterpart in every eukaryotic cell, AMPK has attracted interest in virtually all areas of biological research. Structural and biophysical insights have greatly contributed to a molecular understanding of this kinase. From good old protein biochemistry to modern approaches, such as systems biology and advanced microscopy, all disciplines have provided important information. Thus, multiple links to cellular events and subcellular localizations have been established. Moreover, the crucial involvement of AMPK in human health and disease has been evidenced. AMPK accordingly has moved from an interesting enzyme to a pharmacological target. However, despite our extensive current knowledge about AMPK, the growing community is busier than ever. This book provides a snapshot of recent and current AMPK research with an emphasis on work providing molecular insight, including but not limited to novel physiological and pathological functions, or regulatory mechanisms. Up-to-date reviews and research articles are included.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; HDACs ; transcription ; epigenetics ; spermatozoa ; par complex ; A769662 ; MDCK ; skeletal muscle ; AID ; phosphorylation ; energy metabolism ; monocytes ; autophagy ; CML ; liver ; hindlimb suspension ; pregnancy ; preeclampsia ; gestational diabetes mellitus ; CaMKK2 ; assisted reproduction techniques ; nutrient-sensing signals ; sonic hedgehog ; protein acetylation ; glycogen storage disease ; AMPK ; adenosine monophosphate-activated protein kinase ; AICAR ; indirect calorimetry ; IL-1? ; MyHC I(?) ; HDAC4/5 ; endothelial cells ; infection ; hepatocyte ; p70S6K ; lipid metabolism ; host defense ; exercise ; kidney disease ; heat shock protein ; ?RIM ; mycobacteria ; activation loop ; developmental origins of health and disease (DOHaD) ; CREB ; TAK1 ; metabolic-inflammation ; phenylephrine ; AMP-activated protein kinase (AMPK) ; KATs ; 2-methoxyestradiol ; DNA methylation ; NLRP3 ; pump ; ?-linker ; steatosis ; AMPK kinase ; stress ; endothelial nitric-oxide synthase ; vasodilation ; adherent junctions ; epithelial cells ; glycogen ; Akt ; synaptic activation ; cellular energy sensing ; glucose uptake ; transporter ; co-expression ; atrophy ; nutrigenomics ; motility ; vasoconstriction ; fatty acid oxidation ; oxidative stress ; AS160 ; membrane ; histone modification ; sirtuin 1 (SIRT1) ; chromatin remodeling ; insulin signalling ; dietary fatty acids ; ULK ; CMML ; adaptive thermogenesis ; mTOR ; MDS ; mechanical unloading ; AML ; endothelial function ; medulloblastoma ; PKA ; adipose tissue ; NAD〈sup〉+〈/sup〉 ; membranes ; nutrition ; ZO-1 ; TBC1D4 ; adipocyte ; soluble Adenylyl cyclase ; metabolism ; renin-angiotensin system ; energy utilization ; proteasome ; differentiation ; signaling ; peroxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?) ; hypertrophy ; AMP-activated protein kinase ; metabolic disease ; LKB1 ; soleus muscle ; macrophages ; Immediate early genes ; CBS ; beiging ; motor endplate remodeling ; ionomycin ; nectin-afadin ; tight junctions ; resveratrol ; protein kinase B ; regrowth ; mitochondria ; protein synthesis ; energy deficiency ; catechol-〈i〉O〈/i〉-methyltransferase ; fiber-type ; microarrays ; carrier ; acetyl-CoA ; hypertension ; 3T3-L1 ; hypothalamus ; food intake ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: image/jpeg
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 90
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications.
    Keywords: QH301-705.5 ; Q1-390 ; cotranscriptional folding ; n/a ; RNA ; conditionally activated ; i-motif DNA ; spinal cord tumor ; fluorescence ; dynamic ; stability ; functional RNA ; ribozyme ; biological media ; RNA aptamers ; gene therapy ; biosensors ; viral vector ; ganciclovir ; RNA self-assembly ; RNA nanoparticle ; gene delivery ; riboswitch ; non-viral gene delivery ; NANPs ; silver nanoclusters ; small-angle neutron scattering ; contrast variation ; aptamers ; RNA logic ; fluorogenic RNA ; glioblastoma multiforme ; RNA interference ; nucleic acid nanoparticles ; immunostimulation ; aggregation ; small-angle X-ray scattering ; non-viral vector ; light-up aptamer ; nucleic acid therapeutic ; live-cell imaging ; DNA nanotechnology ; nucleic acid computing ; nanopores ; structural characterization ; siRNA ; suicide gene therapy ; nucleic acid nanoparticle ; cytosine rich sequences ; RNA nanotechnology ; logic gates ; serum ; conditional activation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 91
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: This Special Issue will deal with pathophysiological as well as the phenomenological signs of insomnia. For example, Is ‘hyperarousal’ outdated? What is the difference between acute and chronic insomnia? What sleep disorders are linked to traumatic brain injuries? How is social facial recognition impacted by insomnia? What factors are linked to socioeconomic factors and alcohol consumption in the face of insomnia? We aim to set forward new thinking about insomnia research, including unchartered territories needing to be explored. Reviews, meta-analyses, and new experimental research are welcome in this Issue.
    Keywords: thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 92
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Alzheimer’s disease (AD) is an age-related neurological disease that affects tens of millions of people, in addition to their carers. Hallmark features of AD include plaques composed of amyloid beta, as well as neurofibrillary tangles of tau protein. However, despite more than a century of study, the cause of Alzheimer’s disease remains unresolved. The roles of amyloid beta and tau are being questioned and other causes of AD are now under consideration. The contributions of researchers, model organisms, and various hypotheses will be examined in this Special Issue.
    Keywords: QH301-705.5 ; Q1-390 ; HOTAIR ; neurosciences ; sleep disturbance ; positron emission tomography (PET) ; vitamin B complex ; neurodegeneration ; Tau ; miR-15/107 ; default-mode network ; complement receptor 1 ; neuronal differentiation ; epigenetics ; brain glucose metabolism ; oligomerization ; genetic risk ; A?O receptors ; prion ; ryanodine receptor ; type 3 diabetes ; complement ; cognitive behavioral therapy for insomnia ; cognitive function ; epigenome-wide association study ; Alzheimer’s disease ; calcium signaling ; ?-secretase ; tau ; Prolyl isomerases ; NEAT1 ; complement C3b/C4b receptor ; proteostasis ; amyloid beta ; yeast ; slow-wave sleep ; amyloid ? ; nutrition ; 4 ; protein aggregation ; apolipoprotein E ; dementia ; MALAT1 ; inositol 1 ; lncRNAs ; molecular biology ; methylenetetrahydrofolate reductase MTHFR gene ; 5-trisphosphate receptor ; CR1 density ; miR-34c ; aggregation ; heat shock protein ; dendritic spine ; S-adenosylmethionine ; beta amyloid ; ion channel ; inflammation ; sleep fragmentation ; cystathionine-?-lyase CTH gene ; DNA methylation ; heat shock response ; microglia ; drug target discovery ; amyloid-? oligomer ; therapy ; CR1 length polymorphism ; methylome ; APOE gene ; ubiquitin ; magnetic resonance imaging (MRI) ; neuronal degeneration ; type 2 diabetes ; Pin1 ; mild cognitive impairment ; dairy products ; endoplasmic reticulum ; oxidative stress ; Hispanics ; CDK5R1 ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 93
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: Many things have been said and written on the skeletal and non-skeletal effects of vitamin D, but the largest recent interventional studies are generally negative. How should we thus position ourselves in 2020? Should we say “stop” or “not yet”? Indeed, the aging of the population, as well as new challenges and discoveries, is still triggering interest in this old molecule. In this Special Edition of Nutrients, we invited top experts to give their opinion on this important debate. We also encouraged scientists to submit their latest research on nutritional requirements in the general population and in high-risk groups, as well as treatment strategies, epidemiology, analytical updates and new devices for vitamin D measurement and the effect of vitamin D on bone and extra-skeletal health. As readers will see, this Special Issue reinforces the high prevalence of vitamin deficiency and insufficiency in the general population and supports the safety of this low-cost molecule, revealing new perspectives regarding the extra-skeletal effects of vitamin D.
    Keywords: vitamin D ; obesity ; weight–loss ; body composition ; 25(OH)vitamin D ; biomarkers ; dietary survey ; public health ; EU Menu ; Slovenia ; Europe ; ageing ; older persons ; sensible sun exposure ; cutaneous synthesis ; vitamin D3 ; natural sunlight ; serum 25(OH)D ; autoimmune hepatitis ; primary biliary cholangitis ; health-related quality of life ; mental well-being ; breastmilk ; infant ; mother ; plasma ; vitamin D metabolites ; 3-Epi25(OH)D3 ; 25-hvdroxyvitamin ; vitamin D treatment ; idiopathic hypercalciuria ; urolithiasis ; children ; bone density ; head and neck cancer ; racial disparities ; chemoprevention ; UVB ; microRNA ; proteomic profiling ; vitamin D status ; disability ; very old adults ; vulvovaginal atrophy ; VVA ; vaginal maturation index ; VMI ; vaginal health ; ergocalciferol ; vitamin D supplement ; sunlight exposure ; barriers ; indoor workers ; female ; focus group discussion ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 94
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Iron is an essential element for almost all organisms, a cofactor playing a crucial role in a number of vital functions, including oxygen transport, DNA synthesis, and respiration. However, its ability to exchange electrons renders excess iron potentially toxic, since it is capable of catalyzing the formation of highly poisonous free radicals. As a consequence, iron homeostasis is tightly controlled by sophisticated mechanisms that have been partially elucidated. Because of its biological importance, numerous disorders have been recently linked to the deregulation of iron homeostasis, which include not only the typical disorders of iron overload and deficiency but also cancer and neurodegenerative diseases. This leads iron metabolism to become an interesting therapeutic target for novel pharmacological treatments against these diseases. Several therapies are currently under development for hematological disorders, while other are being considered for different pathologies. The therapeutic targeting under study includes the hepcidin/ferroportin axis for the regulation of systemic iron homeostasis, complex cytosolic machineries for the regulation of the intracellular iron status and its association with oxidative damage, and reagents exploiting proteins of iron metabolism such as ferritin and transferrin receptor. A promising potential target is a recently described form of programmed cell death named ferroptosis, in which the role of iron is essential but not completely clarified. This Special Issue has the aim to summarize the state-of-the-art, and the latest findings published in the iron field, as well as to elucidate future directions.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; developmental ; Anemia of chronic disease ; neurodegeneration ; supplementation ; MHC ; iron chelation therapy ; osteoblast ; serum biomarker ; FeSO4 ; haptoglobin ; prevention ; brain development ; pituitary ; trauma ; hepcidin ; Alzheimer’s disease ; chaotropes ; social behavior ; Africa ; macrophage ; anemia of inflammation ; Tfr2 ; chelation ; cardiomyocyte ; IV iron therapy ; Oxidative stress ; treatment ; chronic kidney disease ; iron homeostasis ; oxygen sensing ; iron chelators ; age-related macular degeneration (AMD) ; pharmaceutical targets ; non-transferrin-bound iron (NTBI) ; iron dextran ; pulmonary arterial hypertension ; labile iron ; low and middle income countries ; ferroportin ; gut microbiota ; reducibility ; non-HFE ; oxidative stress ; antitumor compound ; senescence ; electron transfer ; nanotechnology ; iron deficiency ; neonatal period ; heme oxygenase ; hypoxia ; Anemia ; NCOA4 ; patient blood management ; microbiome ; anemia ; iron mobilization ; iron release ; phlebotomy ; peritoneal dialysis ; Friedreich Ataxia ; ferritin ; CD8+ T cells ; M cells ; neurodegenerative disease ; NaFeEDTA ; vascular calcification ; cinnamic acid derivatives ; oral iron salts ; lipid ; acute lung injury ; Iron-sulfur ; Interleukin-6 ; neurodegeneration with brain iron accumulation ; macrophages ; erythroblastic islands ; cystic fibrosis ; neuroimmune responses ; flavin nucleotide ; hemopexin ; Iron chelators ; nutrient iron ; developing countries ; hereditary hypoferritinemia ; iron ; cancer ; Indonesia ; n/a ; Hfe ; HFE ; chronic heart failure ; iron supplementation ; intestinal inflammation ; TNF ; chelators ; hemolysis ; children ; pulmonary arterial smooth muscle cells ; cytokines ; didox ; intravenous iron ; T lymphocytes ; colorectal cancer ; infants ; liver ; ferritinophagy ; hereditary hyperferritinemia ; SCFA ; rheumatoid arthritis ; membrane interactions ; Sucrosomial® iron ; lung ; Kupffer cell ; iron chelation ; erythrophagocytosis ; acute kidney injury ; neurophysiology ; iron transporters ; iron absorption ; infection ; ferroptosis ; fluorescent iron chelator ; neonatal ; SNC ; immunity ; mycobacteria ; non-haem iron ; natural history ; 3-hydroxy-4-pyridinone ; haem ; inflammation ; bone homeostasis ; cardiovascular disease ; heme ; heme homeostasis ; protein binding ; brain ; iron deficiency anemia ; Fe2+-chelating activity ; bioengineering ; Mek/Erk ; Bmp/Smad ; iron delivery ; genetic hemochromatosis ; osteoclast ; histidine ; rhodamine ; COPD ; hemorrhage ; antibacterial activity ; bacteria ; SLC40A1 ; transferrin receptor ; drug delivery ; nanocage ; soybean seed ferritin ; pig ; iron metabolism ; kidney ; innate immunity ; cataracts syndrome ; erythropoiesis ; obesity ; mucosal immunity ; iron overload ; fluorophore ; binding ability ; inflammatory bowel disease (IBD) ; osteoporosis ; biomarker ; bioavailability ; adverse event profile ; metabolism ; iron-carbohydrate complex ; kinetics ; flavonoids ; iron regulatory proteins ; lung infection ; non transferrin bound iron ; central nurse macrophage ; iron processing ; malaria ; neurodegenerative diseases ; multifunctional iron chelators ; retina ; neuroinflammation ; anti-hepcidin therapy ; lung diseases ; anaemia ; RRM2 ; cognition ; mitochondria ; therapy ; NBIA ; red pulp macrophage ; efficacy ; hemochromatosis ; tolerability ; oral iron therapy ; growth ; venesections ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 95
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Discovered in plants at the turn of the century, microRNAs (miRNAs) have been found to be fundamental to many aspects of plant biology. These small (20–24 nt) regulatory RNAs are derived via processing from longer imperfect double-stranded RNAs. They are then incorporated into silencing complexes, which they guide to (m)RNAs of high sequence complementarity, resulting in gene silencing outcomes, either via RNA degradation and/or translational inhibition. Some miRNAs are ancient, being present in all species of land plants and controlling fundamental processes such as phase change, organ polarity, flowering, and leaf and root development. However, there are many more miRNAs that are much less conserved and with less understood functions. This Special Issue contains seven research papers that span from understanding the function of a single miRNA family to examining how the miRNA profiles alter during abiotic stress or nutrient deficiency. The possibility of circular RNAs in plants acting as miRNA decoys to inhibit miRNA function is investigated, as was the hierarchical roles of miRNA biogenesis factors in the maintenance of phosphate homeostasis. Three reviews cover the potential of miRNAs for agronomic improvement of maize, the role of miRNA-triggered secondary small RNAs in plants, and the potential function of an ancient plant miRNA.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; microRNAs ; abiotic stress ; Arabidopsis thaliana ; heat stress ; photosynthesis ; maize (Zea mays L.) ; immunoprecipitation ; tapetum ; resurrection plants ; plastocyanin ; dehydration ; Tripogon loliiformis ; secondary siRNA ; RT-qPCR ; putrescine ; DRB2 ; phosphate (PO4) stress ; argonaute ; development ; miR399-directed PHO2 expression regulation ; circRNA ; Solanum lycopersicum ; copper deficiency ; salt stress ; DOUBLE-STRANDED RNA BINDING (DRB) proteins DRB1 ; P5CS ; proline ; phasiRNA ; drought stress ; agronomic traits ; Colorado potato beetle ; Cu-microRNA ; plant ; miR171 ; STTM ; aleurone ; PHOSPHATE2 (PHO2) ; vegetative growth ; nutrient availability ; miRNAs ; non-coding RNA ; pollen ; tomato ; flowering ; crop improvement ; callose ; miRNA target gene expression ; circular RNAs ; miRNA ; programmed cell death ; DRB4 ; microRNA (miRNA) ; target mimicry ; MYB transcription factors ; post-transcriptional gene silencing ; desiccation ; miR399 ; miR159 ; copper protein ; drought ; microRNAs (miRNAs) ; microRNA ; GAMYB ; tasiRNA ; phosphorous (P) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 96
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The prevalence of diabetes is on the increase in the UK and worldwide, partly due to changes in lifestyle which predispose individuals to overweight and obesity. It is estimated that about 90% of the currently diagnosed adults have type 2 diabetes, and based on the World Health Organisation (WHO) report, about 422 million adults were living with diabetes in 2014 compared with 108 million in 1980; this condition caused about 1.5 million deaths in 2012. In the United States of America, it is estimated that about 30.3 million adults are living with diabetes, with a further 1.5 million new diabetes cases diagnosed every year, representing an increasing prevalence of this condition. Diabetes represents a major public health challenge, despite advances in technology and the pharmaceutical industry. These problems may be in the form of acute or long-term complications. Therefore, in order to attenuate the problems of diabetes, management strategies usually include lifestyle changes such as increased physical activity and dietary interventions. Studies which evaluate the role of nutrition in the management of type 2 diabetes often involve human and animal models as these approaches enable us to have a broader and more in-depth understanding of the condition. In some cases, diabetes may co-exist with other conditions, such as stroke, and these may present unique challenges with regard to nutritional interventions. This Special Issue aims to evaluate the risk factors associated with type 2 diabetes and the role of the diet in the management of people with this condition. This evidence is drawn from both human and animal studies.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; low-carbohydrate ; lipids ; carbohydrate restricted diet ; aldosterone ; high fat diet ; interleukin-6 ; rosemary extract ; Hedychium coronarium ; isomaltulose ; low carbohydrate diet ; folk medicine ; free fatty acids (FFA) ; high-density lipoprotein cholesterol ; mushroom ; protein and fat counting ; incretins ; fish oil ; almond ; Japanese ; vitamin D deficiency ; low energy diet ; AMPK ; women ; glycaemic index ; T2DM ; zinc status ; ginseng ; longitudinal analysis ; dietary management approaches ; glucose monitoring ; gut microbiome ; nutritional supplement ; carbohydrate counting ; gestational diabetes ; type 2 diabetes mellitus ; very-low-calorie ; inflammatory parameters ; vitamin D ; subjective appetite ; randomised controlled trial ; total body lean ; insulin secretion ; systematic review ; lactic acid bacteria ; food ; type 2 diabetes ; fish ; zinc intake ; glycaemic control ; diabetes ; dairy products ; glycated haemoglobin ; short chain fatty acids ; glycated hemoglobin A ; glycemic control ; vegetable oil ; standard formula ; cardiovascular risk factors ; DASH ; insulin dosage ; appendicular fat ; body composition ; total body fat ; micronutrients ; 25-OH-D ; obesity ; diabetes reversal ; enteral nutrition ; PUFA ; body mass index ; metabolic syndrome ; lifestyle management ; nutrition ; streptozotocin ; nuts ; enteral tube feeding ; lipid profile ; macronutrients ; triglyceride ; tempeh ; cohort study ; diabetes specific formula ; polyunsaturated fatty acids ; diabetes mellitus ; calcium intake ; hyperglycemia ; epidemiology ; trace elements ; dietary intake ; muscle ; appendicular lean ; peanut ; insulin resistance ; sucromalt ; pancreatectomy ; energy restricted diet ; glycemic index ; type 1 diabetes ; fasting blood glucose ; bariatric surgery ; prediabetes ; aronia ; meta-analysis ; chronic conditions ; diabetes management ; dietary pattern ; diet quality ; lipid parameters ; feces ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 97
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: Worldwide, liver fibrosis is a major cause of morbidity and mortality and is associated with a high medical and economic burden. It is the common consequence of chronic liver injury due to various etiologies. During fibrogenesis, there is a progressive substitution of the liver parenchyma by scar tissue. Recent advances in the understanding of the history of liver fibrosis have shown that the pathogenesis is driven by different cell types and a large variety of soluble mediators. At present, scientists working in this field aim to increase basic knowledge, improve diagnostics, and try to translate experimental findings into new treatment modalities. This book includes 12 selected contributions from the Special Issue “Cellular and Molecular Mechanisms Underlying the Pathogenesis of Hepatic Fibrosis” that was published in Cells. These articles summarize current perspectives and findings in hepatic fibrosis research showing how scientists try to use basic scientific research to create new therapies and diagnostics.
    Keywords: thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 98
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The high demand and depletion of petroleum reserves and the associated impact on the environment, together with volatility in the energy market price over the past three decades, have led to tremendous efforts in bio-based research activities, especially in biofuels and biochemicals. Most people associate petroleum with gasoline, however, approximately 6000 petroleum-derived products are available on the market today. Ironically, these petroleum-derived products have not elicited a high level of interest among the populace and media due, in part, to little awareness of the origins of these important products. Given the finite nature of petroleum, it is critical to devote substantial amounts of energy and resources on the development of renewable chemicals, as is currently done for fuels. Theoretically, the bioproduction of gasoline-like fuels and the 6000 petroleum-derived products are within the realm of possibility since our aquatic and terrestrial ecosystems contain abundant and diverse microorganisms capable of catalyzing unlimited numbers of reactions. Moreover, the fields of synthetic biology and metabolic engineering have evolved to the point that a wide range of microorganisms can be enticed or manipulated to catalyze foreign, or improve indigenous, biosynthetic reactions. To increase the concentration of products of interest and to ensure consistent productivity and yield, compatible fermentation processes must be used. Greater agricultural and chemical production during the past three decades, due in part to population increase and industrialization, has generated increasing levels of waste, which must be treated prior to discharge into waterways or wastewater treatment plants. Thus, in addition to the need to understand the physiology and metabolism of microbial catalysts of biotechnological significance, development of cost-effective fermentation strategies to produce biofuels and chemicals of interests while generating minimal waste, or better yet, converting waste into value-added products, is crucial. In this Special Issue, we invite authors to submit original research and review articles that increase our understanding of fermentation technology vis-à-vis production of liquid biofuels and biochemicals, and fermentation strategies that alleviate product toxicity to the fermenting microorganism while enhancing productivity. Further, original research articles and reviews focused on anaerobic digestion, production of gaseous biofuels, fermentation optimization using modelling and simulations, metabolic engineering, or development of tailor-made fermentation processes are welcome.
    Keywords: QH301-705.5 ; lactic acid ; butanediol ; Clostridium pasteurianum ; Escherichia coli ; furfural ; phenolic compounds ; Clostridium beijerinckii ; co-culture ; ethanol ; simultaneous saccharification and fermentation (SSF) ; co-fermentation ; redox ; butanol ; butyric acid ; propanediol ; Miscanthus giganteus ; microalgae ; mixed sugars fermentation ; transcriptomics ; switchgrass ; anaerobic digestion ; cofactors ; Clostridium acetobutylicum ; process integration ; biogas ; techno-economics of production ; hydroxymethyl furfural (HMF) ; glycerol ; isopropanol ; synthetic biology ; biotransformation ; corn stover ; lignocellulose derived microbial inhibitory compounds (LDMICs) ; succinic acid ; bioreactors ; metabolic engineering ; syngas fermentation ; lignocellulose ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 99
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Dietary fiber has long been recognized for its role in digestive function. However, currently there is scientific debate about definitions (descriptive and analytical), optimal intake, and essentiality in the human diet. Dietary fiber is a key substrate for bacterial metabolism in the colon, which makes research on dietary fiber an important issue that complements current interest in the gut microbiota. Dietary fiber is also important for prevention and management of cardiovascular disease, diabetes, obesity, and other chronic diseases. This Special Issue will highlight recent research on dietary fiber content in foods and function in human health, ranging from digestive function to chronic disease prevention and management.
    Keywords: QH301-705.5 ; Definition ; Dietary fiber ; Fermentation ; Prebiotic ; Glucose control ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 100
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-01
    Description: The structure, uniformity, stability, and functions of virus-like particles (VLPs) have encouraged scientists to utilize them as a unique tool in various applications in biomedical fields. Their interaction with the innate immune system is of major importance for the adaptive immune response they induce. The innate immune cells and molecules recognize and interact with VLPs on the basis of two major characteristics: size and surface geometry. VLP-based vaccines against hepatitis B, human papilloma, malaria, and hepatitis E have been developed and are available in many countries around the world. Given the inherent immunogenicity of VLPs, they render themselves ideal for the development of new vaccines against infectious diseases as well as noncommunicable diseases, such as chronic inflammation or cancer. This Special Issue is designed to provide an up-to-date view of the latest progress in the development of VLP-based prophylactic and therapeutic vaccines and technologies for their generation.
    Keywords: virus-like particle ; influenza A(H1N1)pdm09 ; vaccination ; pregnant women ; antibody titers ; norovirus ; VLP ; vaccine ; genotype ; pre-existing immunity ; cross-reactivity ; blocking antibodies ; original antigenic sin (OAS) ; HPVs ; vaccines ; virus-like particles (VLPs) ; minor capsid protein (L2) ; HCMV ; cytomegalovirus ; nanoparticle ; immune response ; Sudan virus ; mice ; horse ; purified IgG ; long-lived plasma cells ; antibodies ; multivalency ; virus-like particles ; antigenic analysis ; epitope characterization ; hepatitis E vaccine ; serological evaluation ; virion-like epitopes ; well-characterized vaccines ; hepatitis B virus ; surface (envelope) antigen ; sub-viral particle ; capsid ; antigen display ; platform ; viral quantification ; NTA ; flow virometry ; SRFM ; cryo-TEM ; SEM ; plant virus ; virus-like ; vaccine platform ; epitope ; antigen ; cat allergy ; Fel d 1 ; HypoCat™ ; IL-13 ; interleukin-13 ; Tfh cells ; cancer ; immunotherapy ; H7N9 ; pandemic influenza A ; avian flu ; IAV ; VLP vaccine ; n/a ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues
    Language: English
    Format: application/octet-stream
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...