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  • Other Sources  (14)
  • Spiegel-Verlag Rudolf Augstein GmbH & Co. KG  (10)
  • American Meteorological Society
  • Springer Nature
  • Taylor & Francis
  • 2020-2023  (10)
  • 2020-2022  (4)
  • 1890-1899
  • 2020  (14)
  • 2020  (14)
  • 1
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    Marine bacteria as source of antimicrobial compounds (2020)
    Taylor & Francis
    In:  Critical Reviews in Biotechnology . pp. 1-14.
    Details
    Publication Date: 2021-01-08
    Description: The marine environment encompasses a huge biological diversity and can be considered as an underexplored location for prospecting bioactive molecules. In this review, the current state of art about antimicrobial molecules from marine bacteria has been summarized considering the main phylum and sources evolved in a marine environment. Considering the last two decades, we have found as most studied group of bacteria producers of substances with antimicrobial activity is the Firmicutes phylum, in particular strains of the Bacillus genus. The reason for that can be attributed to the difficult cultivation of typical Actinobacteria from a marine sediment, whose members are the major producers of antimicrobial substances in land environments. However, a reversed trend has been observed in recent years with an increasing number of reports settling on Actinobacteria. Great diversity of chemical structures have been identified, such as fijimicyns and lynamicyns from Actinomycetes and macrolactins produced by Bacillus.
    Type: Article , PeerReviewed
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  • 2
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    Metabolomic tools used in marine natural product drug discovery (2020)
    Taylor & Francis
    In:  Expert Opinion on Drug Discovery, 15 (4). pp. 499-522.
    Details
    Publication Date: 2021-01-08
    Description: Introduction: The marine environment is a very promising resource for natural product research, with many of these reaching the market as new drugs, especially in the field of cancer therapy as well as the drug discovery pipeline for new antimicrobials. Exploitation for bioactive marine compounds with unique structures and novel bioactivity such as the isoquinoline alkaloid; trabectedin, the polyether macrolide; halichondrin B, and the peptide; dolastatin 10, requires the use of analytical techniques, which can generate unbiased, quantitative, and qualitative data to benefit the biodiscovery process. Metabolomics has shown to bridge this understanding and facilitate the development of new potential drugs from marine sources and particularly their microbial symbionts. Areas covered: In this review, articles on applied secondary metabolomics ranging from 1990–2018 as well as to the last quarter of 2019 were probed to investigate the impact of metabolomics on drug discovery for new antibiotics and cancer treatment. Expert opinion: The current literature review highlighted the effectiveness of metabolomics in the study of targeting biologically active secondary metabolites from marine sources for optimized discovery of potential new natural products to be made accessible to a R&D pipeline.
    Type: Article , PeerReviewed
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  • 3
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    Trans-European Suture Zone (2020)
    Springer Nature
    In:  In: Encyclopedia of Solid Earth Geophysics. , ed. by Gupta, H. Encyclopedia of Earth Sciences Series . Springer Nature, Cham, Switzerland, , 11 pp. ISBN 978-3-030-10475-7
    Details
    Publication Date: 2021-02-10
    Description: The Trans-European Suture Zone (TESZ) is the transition zone from the Precambrian East European Craton in the north and east to the younger Phanerozoic mobile belts to the south and west. It is the most prominent lithospheric tectonic feature of Europe. The term Trans-European Suture Zone was only adapted around year 2000 during the Pan-European EUROPROBE program of the European Science Foundation. Until then, parts of the zone were termed Teisseyre-Tornquist Zone, Sorgenfrei-Tornquist Zone, Trans-European Fault, and Tornquist Fan.
    Type: Book chapter , NonPeerReviewed
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  • 4
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    Chemosystematic evaluation of Amazonian freshwater sponges (2020)
    Taylor & Francis
    In:  Natural Product Research . pp. 1-5.
    Details
    Publication Date: 2021-01-08
    Description: Freshwater sponges can be considered a promising new source of bioactive compounds for the pharmaceutical industry; however, the research on their chemical composition is still in the incipient stage. We evaluated the most endemic Amazonian freshwater sponge species from the Drulia and Metania genera by untargeted metabolomic approaches, based on UHPCL-HRMS, in order to identify chemical markers and explore the diversity of specialized metabolites. The use of untargeted approaches allowed us to observe subsets of metabolites that enabled the characterization of, not only each genus, but also, of each species. Freshwater sponge species presented themselves as rich sources of fatty acids and sterols, which were putatively identified. These metabolites were suggested as chemical markers for further targeted metabolomic studies.
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  • 5
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    Was der Eisverlust in der Arktis für uns bedeutet (2020)
    Spiegel-Verlag Rudolf Augstein GmbH & Co. KG
    In:  SPIEGEL Online : Wissenschaft
    Details
    Publication Date: 2022-03-21
    Description: In der Arktis hat der Juli Hitzerekorde, ausufernde Brände und massiven Eisschwund gebracht. Die Folgen kommen auch bei uns in Deutschland an.
    Type: info:eu-repo/semantics/other
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  • 6
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    Bei diesen Fragen ist was faul (2020)
    Spiegel-Verlag Rudolf Augstein GmbH & Co. KG
    In:  SPIEGEL Online : Wissenschaft
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    Publication Date: 2022-03-21
    Description: Am Freitag starten Klimawandelleugner eine neue Offensive - sie schicken 16 unschuldig anmutende Fragen an Bundestagsabgeordnete. Bei genauem Blick entpuppt sich die Schrift als pure Propaganda.
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  • 7
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    "Biden ist ein echter Neuanfang" [Interview] (2020)
    Spiegel-Verlag Rudolf Augstein GmbH & Co. KG
    In:  SPIEGEL Online: Wirtschaft
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    Publication Date: 2022-03-21
    Description: Vor wenigen Tagen traten die USA aus dem Pariser Klimaabkommen aus – das könnte jetzt revidiert werden. Was Umweltökonom Ottmar Edenhofer sonst noch vom neuen Präsidenten erwartet.
    Language: German
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  • 8
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    Warum der Meeresspiegel immer schneller steigt (2020)
    Spiegel-Verlag Rudolf Augstein GmbH & Co. KG
    In:  SPIEGEL Online : Wissenschaft
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    Publication Date: 2022-03-21
    Description: Der Meeresspiegel steigt. Und nicht nur das: Er steigt immer schneller. Wie stark der Klimawandel diesen Effekt treibt, ist inzwischen weitgehend entschlüsselt – auch dank moderner Satellitentechnik.
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  • 9
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    Warum jetzt sogar Wälder den Klimawandel anheizen könnten (2020)
    Spiegel-Verlag Rudolf Augstein GmbH & Co. KG
    In:  SPIEGEL Online : Wissenschaft
    Details
    Publication Date: 2022-03-21
    Description: Nicht alles CO2, das wir in die Luft pusten, bleibt dort. Ozeane und Wälder schlucken mehr als die Hälfte davon. Das hilft uns - aber wie lange noch?
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  • 10
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    Woher die gewaltige Energie des Klimawandels stammt (2020)
    Spiegel-Verlag Rudolf Augstein GmbH & Co. KG
    In:  SPIEGEL Online : Wissenschaft
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    Publication Date: 2022-03-21
    Description: In jedem Liter eingeatmeter Luft stecken 3.432.000.000.000.000.000 CO2-Moleküle fossiler Brennstoffe. Gesundheitsschädlich ist das zwar nicht - aber man muss es wissen, um den Klimawandel zu verstehen.
    Type: info:eu-repo/semantics/other
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