ALBERT

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Hyperspectral systems that image drill core can capture detail mineralogical information at the millimeter scale and thus have the potential to enable investigators to characterize shale composition and heterogeneity, complementing the direct chemical and x-ray diffraction analysis of core samples and guiding detailed sampling. This method provides insight into petrophysical and geomechanical properties because these properties are significantly correlated to rock composition. We tested this approach on a continuous long core from the shale sequence of the Horn River Group in the Horn River Basin, British Columbia, sampled at a spacing of 1 m (40 in.) and analyzed for geochemical composition. These data enable the calibration of spectral imagery to rock composition and specifically predict total organic carbon (TOC) and the abundance of SiO〈sub〉2〈/sub〉, Al〈sub〉2〈/sub〉O〈sub〉3〈/sub〉, K〈sub〉2〈/sub〉O, and CaO. We then imaged nine samples from the Woodford Shale from the Permian Basin, Texas, for a blind test to assess the predictive models. The models were then used to predict TOC and geochemical data over detailed imagery of 300 m (984 ft) of Horn River Group shale core and portray their spatial variability downhole as images and profiles. In its simplest form, hyperspectral imagery can be enhanced to highlight fabric in shale core that otherwise is difficult to visualize because of low brightness. In addition, we show that spectral imagery of shale can also be processed to either convey mineralogical (quartz, clay, and carbonate) or geochemical information. The resulting views can readily be used to guide the selection of samples and may provide tools for scaling reservoir properties from individual plugs to reservoir volumes.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Considerable attention has been directed to the Devonian Horn River Formation in western Canada with respect to geochemical evaluation of gas-generation and storage potential. Because organic geochemical analyses are not always useful for characterizing the type and amount of original organic matter, we surmise the original kerogen type and original hydrogen index (HIo) and subsequently estimate a reliable original total organic carbon (TOCo) based on a combination of inorganic and organic geochemical data. Productivity (SiO〈sub〉2〈/sub〉 and Ba) and terrestrial input (Al〈sub〉2〈/sub〉O〈sub〉3〈/sub〉, Hf, Nb, and Zr) proxies are used to estimate original kerogen types, which suggest that the Evie and Muskwa Members formed under conditions of high productivity and minor terrestrial input. These members also formed under reducing conditions, as indicated by the redox proxies (Mo, U, and Th/U). Under such conditions, primarily type II kerogen was preserved.By considering the fraction of biogenic silica, the estimated HIo values (400–500 mg hydrocarbon/g total organic carbon [TOC]) for the middle Otter Park Member are lower than that for Evie and Muskwa Members and higher than the upper and lower Otter Park Member. The stronger correlation between TOCo and trace elements suggests that HIo is useful for reconstructing the coherent variation in TOCo. Based on the original kerogen type and TOCo, the gas-generation and storage potentials of the Evie, middle Otter Park, and Muskwa Members are higher than those of other members. The source-rock potential is excellent for the Evie Member with an approximately 75% difference between TOCo and measured present-day TOC.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The global Precambrian–Cambrian system includes an important series of hydrocarbon-bearing strata. However, because rocks of this age are typically deeply buried, few petroleum exploration breakthroughs have been made, and the presence of source rocks remains somewhat controversial. Recently, commercial condensate and gas were discovered from the deep (∼6900 m [∼22,600 ft]) Zhongshen 1C (ZS1C) exploratory well drilled in the Tazhong uplift of the Tarim Basin, China, leading to renewed interest in the development of Cambrian source rocks in the basin. On the basis of outcrop reconnaissance and sample testing from around the Tarim Basin, we show that a set of high-quality source rocks were developed within the lower Cambrian Yuertusi Formation (Є〈sub〉1〈/sub〉y), at the base of the lower Cambrian. These rocks are black shales and typically have a total organic carbon content between 2% and 6% but extending as high as 17% in selected regions. This marine sequence is 10–15 m (33–49 ft) thick in some outcrops along the margins of the basin. Seismic data indicate that these high-quality source rocks may cover an area as large as 260,000 km〈sup〉2〈/sup〉 (100,000 mi〈sup〉2〈/sup〉). Their main organic parent material was benthic multicellular algae. On the basis of high-temperature thermal simulations conducted on these source rocks, we show that the gas composition and carbon isotopes from the ZS1C well are similar to the products generated at a thermal evolution stage corresponding to a vitrinite reflectance of between 2.2% and 2.5%. Late-stage natural gas accumulated within these rocks over time. The δ〈sup〉34〈/sup〉S correlation of organic sulfur compounds in the condensate with Cambrian sulfates provides further evidence for a Є〈sub〉1〈/sub〉y source rock origin of the ZS1C condensate and gas. The Cambrian dolomites in association with a salt seal exhibit favorable geological conditions for large-scale hydrocarbon accumulation. A new set of deep exploration strata can, therefore, be developed, guiding future deep Cambrian hydrocarbon exploration in the Tarim Basin.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The effects of reservoir heterogeneity on the development of submarine channel fields are still poorly understood because of lack of direct evidence for fluid flow. This study uses integrated well logs and three-dimensional seismic data from the Niger Delta Basin to characterize the previously undocumented spatial distribution of shale units and permeability contrasts within a submarine channel system. Combining these data with four-dimensional (4-D) seismic data facilitates the exploration of the controls of reservoir heterogeneity on fluid flow during development. The results show that the studied submarine channel system consists of multiple vertically stacked channel complex sets (CCSs) from CCS1 (oldest) to CCS5 (youngest), which are separated from each other by continuous shale barriers. The CCS2–CCS4, which are located in the stratigraphic middle of the channel system, are the main development layers because of their higher permeabilities and lower permeability contrasts. The 4-D seismic responses validate that the presence of shale barriers between vertically adjacent CCSs can hinder the flow of fluids between CCSs. Fluid flow between vertically adjacent CCSs barely occurs except in localized erosional locations where the sand fills of different CCSs are vertically connected. Each CCS consists of multiple individual channels, which can be separated by inclined shale baffles if they laterally migrate in one direction. As the 4-D seismic responses demonstrate, such inclined shale baffles can hinder fluid flow between adjacent individual channels and help to form multiple narrow flow paths in map view. The absence of inclined shale baffles also produces prominent permeability contrasts within each CCS, which are characterized by relatively high–permeability zones that are parallel to the channel axis. Comparison of this permeability distribution and the 4-D seismic responses shows that injected water preferentially sweeps along relatively high–permeability zones, which can help to form single wide flow paths with higher sweep efficiency or single narrow flow paths with lower sweep efficiency.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Source-to-sink analyses show that northern Gulf of Mexico (GOM) Wilcox Group siliciclastic deep-water systems are linked to transport of sediments from the Laramide tectonic belt into the deep basin. Less is known, however, about southern GOM sedimentation. New drilling and discoveries in the Mexican deep water have generated considerable interest since the opening of Mexico to international exploration. To investigate Paleogene deposition in Mexico’s offshore areas, a three-phased approach was employed: (1) seismic mapping of deep-water depocenters, (2) regional stratigraphic analysis of potential basin entry points, and (3) prediction of submarine-fan dimensions using empirical scaling relationships. Isochore and structural mapping of the Wilcox depocenters used available well and seismic data. Potential basin entry points were identified by evaluation of Wilcox fluvial–deltaic systems and tectonic elements. Empirical scaling relationships previously established between fluvial and deep-water segments provide first-order predictions of submarine-fan dimensions.Paleogene Wilcox source-to-sink systems of the greater GOM basin change north to south as a function of varied tectonics and sedimentary accommodation. The United States sector was a passive margin: continental-scale drainage systems fed a broad, gently dipping shelf. By contrast, the southern GOM basin was a tectonically active margin: smaller-scale fluvial systems sourced from the Hidalgoan uplands flowed directly into foreland basins located on the slope. Results presented here indicate that several systems rimming the southern GOM were able to effectively transfer sediment from the mountain belt into the basin. Regional observations and semiquantitative predictions of fan dimensions provide a context for future detailed work based on new well and seismic information.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Sequence stratigraphy based on wire-line logs, cores, and outcrops is entering its fourth decade of mainstream usage in industry and academia. The technique has proved to be an invaluable tool for improving stratigraphic analyses in both clastic and carbonate settings. Here we present a simple quantitative technique to support sequence stratigraphic interpretations in clastic shallow marine systems. The technique uses two pieces of data that are readily available from every subsurface field or outcrop study: (1) parasequence thickness (T) and (2) parasequence sandstone fraction (SF). The key assumptions are that parasequence thickness can be used as a proxy for accommodation at the time of deposition and parasequence sandstone fraction can be used as a proxy for sediment supply. This means that quantitative proxies for rates of accommodation development and sediment supply can be acquired from wire-line logs, cores, and outcrop data. Vertical trends in parasequence thickness divided by sandstone fraction (T/SF) approximate trends expected in systems tracts for changes in ratios of rate of accommodation development to rate of sediment supply. The technique, termed “TSF analysis,” can also be applied at lower-order sequence and composite sequence scales. It provides a quantitative and objective methodology for determining rank and order of sequence stratigraphic surfaces and units. Absolute T/SF values can be used to determine shoreline, stacked shoreline, and shelf-margin trajectories. Four case studies are presented, which demonstrate the robustness of the technique across a range of different data sets. Implications and potential future applications of TSF analyses are discussed.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The Eagle Ford Formation has attracted considerable industry attention as a self-sourced unconventional shale reservoir. The productive interval in the Eagle Ford Formation is the transgressive systems tract, which contains parasequences whose lithologic content varies upward with increasing proportions of limestones. Optimum success in both exploration and production depends on the adequate characterization of fracture systems as a function of lithology. The outcrops present along US Highway 90 in Val Verde and Terrell Counties, Texas, provide considerable insight into the regional natural fracture system of the Eagle Ford Formation. Fracture-orientation analysis reveals two sets of conjugate hybrid shear fractures and two sets of regional fractures. Abutting relationships suggest that hybrid shear fractures formed first, followed by the thoroughgoing northeast-striking fracture set, and finally by a northwest-striking set, which tends to be confined to individual mechanical units. The orientation of these fractures suggests that they formed during post-Laramide stress relaxation and progressive exhumation. Spacing-frequency distribution analysis of the fracture population reveals a mature hypersaturated fracture system that likely formed at depth by overburden load and/or fluid pressure near maximum burial. Our results indicate that the Eagle Ford Formation displays a well-developed fracture network regionally distributed in the Val Verde Basin, and likely present in the productive Eagle Ford play. These observations provide evidence for pathways and vertical connectivity for potential fluid pathways throughout the Eagle Ford Formation.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉We document a novel approach to balanced three-dimensional structural restoration based on an adaptation of the GeoChron model. Conventionally, the GeoChron model defines a transformation of a geological model to a flattened space (U-V-T), with paleogeographic coordinates defined by the horizontal axes (U-V) and geologic time on the vertical axis (T). In our new balanced structural restoration scheme, the complete stratigraphy is restored using a transformation constrained only by the datum horizon. Scaling the vertical “T” axis to depth in a manner that preserves volume or layer thickness results in a geometric restoration that approximately minimizes strain globally. This restoration provides a geometrically plausible representation of the geologic structure at the time when the datum horizon was deposited. Restoration is independent of mechanical rock properties and is thus most applicable to regions in which mechanical rock properties are approximately homogeneous. Restoration kinematics may be constrained by growth strata if present.We validate the method with kinematic forward models and a laboratory sandbox model and apply it to two natural examples to demonstrate its capabilities for model validation and palinspastic restoration.We identify four criteria for assessing the validity of a structural model using the results of restoration: (1) anomalous fault throw, (2) timing of fault activity, (3) fault compliance, and (4) restoration strain. Analysis of the sandbox results and limitations of volume conservation derived from uncertainties in compaction states suggest accuracy of the method to be in the 5%–20% range.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The pore structure of shale has a significant effect on hydrocarbon migration and the long-term gas supply of shale gas wells. The present study investigates the spontaneous imbibition characteristics to evaluate the pore connectivity and wettability of marine Longmaxi shale samples from the southeastern Chongqing area and continental Yanchang shale samples from the Ordos Basin. The pore-size distribution obtained from N〈sub〉2〈/sub〉 adsorption and mercury intrusion porosimetry, field emission–scanning electron microscopy, and focused ion beam–scanning electron microscopy photos are used to interpret the imbibition behaviors. Our results show that the difference in dominant pore type between marine and continental samples, which is dominated by thermal maturity, controls on their imbibition behaviors as well as their wettability. Organic matter (OM) pores within Yanchang samples are poorly developed because of their low thermal maturity, and a large amount of water-wet inorganic pores are preserved in these samples because of relatively weak compaction. Oil-wet OM pores are well developed in Longmaxi samples with higher thermal maturity, and inorganic pores have been largely eliminated because of strong compaction. The low pore connectivity to water for both the Longmaxi and Yanchang samples is indicated by the low water imbibition slopes. Furthermore, the more oil-wet property of the Longmaxi samples and more water-wet characteristics of the Yanchang samples are obtained by comparing the directional water/oil imbibition slopes. In addition, the positive meaning of quartz in the protection of pore spaces is found in both the Longmaxi and the Yanchang samples used in this study.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Multiple natural gas fields have been discovered in the Baiyun depression and the adjoining Panyu lower uplift in the Pearl River Mouth Basin, northern South China Sea. The natural gases are associated with condensate and are characterized by relatively heavy carbon isotopes, with methane and ethane δ〈sup〉13〈/sup〉C values ranging from –44.2‰ to –33.6‰ and –30.0‰ to –25.4‰, respectively. Nearly all methane and ethane are derived from oil-prone type II kerogen in the Wenchang Formation source rock, whereas the heavy hydrocarbon gases (propane, butanes, and pentanes) are derived from both the Wenchang and Enping (type III kerogen) Formations, based on an integrated comparison of carbon isotopic compositions of the natural gases, typical type I/II and type III kerogen-derived gases, and the Enping and Wenchang kerogens. The gases from the eastern parts of the Baiyun depression and the Panyu lower uplift mainly originate from secondary oil cracking and primary kerogen cracking, respectively. The gases from the northern slope of the Baiyun depression are a mixture of oil-cracking and kerogen-cracking gases. Both oil-cracking and kerogen-cracking gases were mainly generated from the Wenchang Formation source rock in the maturity range of 1.5%–2.5% vitrinite reflectance, with a corresponding present-day depth range of 5400–6500 m (17,700–21,300 ft). The apparent contribution of the Wenchang Formation to the discovered gas accumulations demonstrates that it is the most important source rock in the area, instead of the Enping Formation. The search for more gas derived from oil cracking will be the next natural gas exploration direction in the Baiyun depression.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The northern Appalachian Basin depocenter of Pennsylvania represents one of the most economically important hydrocarbon-producing areas in the United States, yet the thermal conditions that promoted hydrocarbon formation within the basin are only marginally constrained. The prolific coal, oil, and natural gas fields of Pennsylvania are the direct result of thermal maturation of once deeply buried organic-rich sediment. Understanding how, why, and where thermal maturation occurred in the Appalachian Basin requires high-quality heat flow and thermal conductivity measurements, as well as paleotemperature estimates and basin modeling. To improve the understanding of heat flow, we present, to our knowledge, the first direct measurements of (1) thermal conductivity on Devonian core samples and (2) equilibrium temperature versus depth logs for the northern Appalachian Basin depocenter. Results from three well sites demonstrate that heat flow is conductive and nearly uniform, averaging 34 ± 2.5 mW/m〈sup〉2〈/sup〉, with an average thermal gradient of 29 ± 4°C/km. The new heat-flow measurements are significantly lower (30%–50% less) than previously published estimates that used nonequilibrium bottomhole temperature values and empirically derived thermal conductivity estimates. Our analysis indicates that previous studies correctly estimated the regional thermal gradient using bottomhole temperatures but overestimated heat flow in this region by as much as 50% because of inaccurate extrapolation of thermal conductivity. The results highlight the importance of directly measuring thermal conductivity to accurately quantify heat flow in deep sedimentary basins. Ultimately, additional paleotemperature data are necessary to improve our understanding of Appalachian Basin thermal evolution.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Shale samples of the Marcellus Shale from a well drilled in northeastern Pennsylvania were used to study diagenetic effects on the mineral and organic matter and their impact on petrophysical response. We analyzed an interval of high gamma ray and anomalously low electrical resistivity from a high thermal maturity (mean maximum vitrinite reflectance 〉 4%) part of the shale‐gas play. A suite of microanalytical techniques was used to study features of the shale down to the nanoscale and assess the level of thermal alteration of the mineral and organic phases.The samples are organic rich, with total organic carbon contents of 3–7 wt. %; the vast majority of the organic matter was identified as highly porous pyrobitumen. Matrix porosity is also present, especially within the clay aggregates and at the interface between rigid clasts and clay minerals.Mineral- and organic-based thermal maturity indices suggest that during burial the sediment had been exposed to temperatures as high as 285°C (545°F). Under these conditions, the residual, migrated organic matter assumed a partially crystalline habit as confirmed by the identification of turbostratic structures via electron microscopy imaging. Experimental dielectric measurements on organic matter–rich samples confirm that the anomalous electrical properties observed in the wire-line logs can be ascribed to the presence of an electrically conductive interconnected network of partially graphitized organic matter. The preservation of porosity suggests that this organic network can contribute not only to the electrical properties but also to the gas flow properties within the Marcellus Shale.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Understanding natural fracture networks in the subsurface is highly challenging, as direct one-dimensional borehole data are unable to reflect their spatial complexity, and three-dimensional seismic data are limited in spatial resolution to resolve individual meter-scale fractures.Here, we present a prototype workflow for automated fracture detection along horizontal scan lines using terrestrial light detection and ranging (t-LIDAR). Data are derived from a kilometer-scale Pennsylvanian (locally upper Carboniferous) reservoir outcrop analog in the Lower Saxony Basin, northwestern Germany. The workflow allows the t-LIDAR data to be integrated into conventional reservoir-modeling software for characterizing natural fracture networks with regard to orientation and spatial distribution. The analysis outlines the lateral reorientation of fractures from a west–southwest/east–northeast strike, near a normal fault with approximately 600 m (∼1970 ft) displacement, toward an east–west strike away from the fault. Fracture corridors, 10–20 m (33–66 ft) wide, are present in unfaulted rocks with an average fracture density of 3.4–3.9 m〈sup〉−1〈/sup〉 (11.2–12.8 ft〈sup〉−1〈/sup〉). A reservoir-scale digital outcrop model was constructed as a basis for data integration. The fracture detection and analysis serve as input for a stochastically modeled discrete fracture network, demonstrating the transferability of the derived data into standard hydrocarbon exploration-and-production-industry approaches.The presented t-LIDAR workflow provides a powerful tool for quantitative spatial analysis of outcrop analogs, in terms of natural fracture network characterization, and enriches classical outcrop investigation techniques. This study may contribute to a better application of outcrop analog data to naturally fractured reservoirs in the subsurface, reducing uncertainties in the characterization of this reservoir type at depth.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Using cores, well logs, and other borehole data, the results of this study show that the shallow-water lacustrine delta has its own unique depositional characteristics of the third member of Oligocene Dongying Formation (Ed〈sub〉3〈/sub〉) in the Baxian sag, Bohai Bay Basin, eastern China. During the Ed〈sub〉3〈/sub〉 stage, the rift–thermal basin subsidence transition stage, the paleoslope was divided into multilevel slopes by faults along the Wen’an slope with slope angles from approximately 0.19° to 2.02°. The paleogeographic conditions, low-discharge channel, and low accommodation controlled the sedimentary characteristics. The distributions of the shallow-water delta system were controlled by multilevel flexure slopes. The delta plain was distributed on the first- and second-level slope belts, and the delta front was distributed on the third-level slope belt. The high-sinuosity fluvial channel of the delta plain was the dominant facies in the whole shallow-water delta. Most sand was deposited in these channels along the second-level slope belt. Therefore, not enough sand was present to be transported into the lake (shallow water) to form mouth bars in the delta front. Therefore, mouth bars of the shallow-water delta front were few, and the sand beds were thin. Additionally, no more sand was available to be supplied right along to deep lake, the lacustrine basin was small, and there was insufficient accommodation and sand to develop a subaqueous fan in the delta front.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Three-dimensional reservoir modeling is an important aspect to determine the heterogeneity of organic-rich shale reservoirs, an area of study that continues to be explored and refined. A large proportion of data acquired from horizontal wells causes issues in the structural and property modeling for shale reservoirs. Since horizontal wells are designed to drill into a specific, narrow zone, their horizontal section tends to parallel or nearly parallel formation surfaces. As a result, formation surfaces have a much more complex spatial location relationship with horizontal wellbores than with vertical wellbores. The existing algorithms are not good at addressing this issue during structural modeling. The major problem of using horizontal well data in property modeling is the biased data set because their horizontal section tends to stay within a narrow zone. The property distribution feature estimated from this biased data set, as a significant, default input of geostatistical simulation algorithms, causes the constructed property models to deviate away from the real case in the subsurface. A method to infer more formation tops in pseudovertical wells according to a series of assumptions was developed to provide more constraint points for structural modeling within the areas of the horizontal well section. To use the biased database from horizontal wells, distribution function and trend model methods were developed for continuous property modeling, and percentage and probability trend models were developed for discrete property modeling. The Longmaxi–Wufeng shale in the Fuling gas field of Sichuan Basin was used as an example to express and verify these methods.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉An integrated approach to detect new areas of potential interest associated with stratigraphic traps in mature basins is presented. The study was carried out in the Middle Magdalena Valley basin, Colombia. The workflow integrates outcrop and subsurface interpretations of facies, activity of faults, and distribution of depocenters and paleocurrents and makes use of them to construct a three-dimensional exploration-scale geocellular facies model of the basin. The outcrop and well log sedimentological analysis distinguished facies associations of alluvial fan, overbank, floodplain, and channel fill, the last one constituting the reservoir rock. The seismic analysis showed that tectonic activity was coeval with the deposition of the productive units in the basin and that the activity ended earlier (before the middle Miocene) along the western margin than along the eastern margin. Paleogeographic reconstructions depict transverse and longitudinal fluvial systems, alluvial fans adjacent to the active basin margins, and floodplain facies dominating the structural highs and the southwestern depositional limit. These reconstructions provided statistical data (lateral variograms) to construct the model. The exploration-scale facies model depicts the complete structure of the basin in three dimensions and the gross distribution of the reservoir and seal rocks. The predictive capability of the model was evaluated positively, and the model was employed to detect zones of high channel fill facies probability that form bodies that are isolated or that terminate upward in pinchouts or are truncated by a fault. Our approach can prove helpful in improving general exploration workflows in similar settings.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Knowledge of in situ stress distribution is fundamental for coalbed methane production; however, it is poorly understood in the eastern Yunnan region, South China. In this study, the horizontal maximum (〈span〉S〈/span〉〈sub〉〈span〉Hmax〈/span〉〈/sub〉) and minimum (〈span〉S〈/span〉〈sub〉〈span〉hmin〈/span〉〈/sub〉) principal stress and vertical stress (〈span〉S〈/span〉〈sub〉〈span〉v〈/span〉〈/sub〉) were systematically analyzed for the first time. The results indicated that the magnitudes of 〈span〉S〈/span〉〈sub〉〈span〉Hmax〈/span〉〈/sub〉, 〈span〉S〈/span〉〈sub〉〈span〉hmin〈/span〉〈/sub〉, and 〈span〉S〈/span〉〈sub〉〈span〉v〈/span〉〈/sub〉 showed positive correlations with burial depth. In general, three types of in situ stress fields were determined: (1) 〈span〉S〈/span〉〈sub〉〈span〉Hmax〈/span〉〈/sub〉 〉 〈span〉S〈/span〉〈sub〉〈span〉v〈/span〉〈/sub〉 〉 〈span〉S〈/span〉〈sub〉〈span〉hmin〈/span〉〈/sub〉 in shallow layers with burial depths less than approximately 600 m (∼1970 ft) below ground level (bgl), indicating a dominant strike-slip faulting stress regime; (2) in medium layers approximately 600–800 m (∼1970–2625 ft) bgl, the in situ stress state followed multiple relationships, suggesting that the in situ stress regime was transformed; and (3) 〈span〉S〈/span〉〈sub〉〈span〉v〈/span〉〈/sub〉 〉 〈span〉S〈/span〉〈sub〉〈span〉Hmax〈/span〉〈/sub〉 〉〈span〉S〈/span〉〈sub〉〈span〉hmin〈/span〉〈/sub〉 in deep layers with burial depths greater than approximately 800 m (∼2625 ft) bgl, indicating a dominant normal faulting stress regime. Coal permeabilities obtained from injection–falloff well tests showed that they were widely distributed, and no obvious relationships were found between coal permeability and effective in situ stress magnitude. In the study area, the development and orientation of previously generated natural fractures combined with the present-day in situ stress distribution controlled the permeability in coal reservoirs. Differential stress and presence of natural fractures significantly affected the geometry and pattern of hydraulic fractures. In addition, in the eastern Yunnan region, locations with relatively deep depths in vertical wells and approximately west–northwest/east–southeast-trending horizontal wells suffered high potential of borehole instability because of the high differential stress.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉In carbonate rock reservoirs, spatial distribution models and elastic properties are complex because of diagenetic processes and mineralogical composition, which together directly interfere with variations in pore shape and interconnectivity. The main objective of this paper is to propose a workflow to aid in three-dimensional quantitative carbonate reservoir characterization of the Quissamã Formation (Macaé Group) in the Pampo field of the Campos Basin, offshore Brazil. Model-based seismic inversion, sequential Gaussian simulation with cokriging for porosity modeling, and truncated Gaussian simulation with trend for facies modeling were used to characterize the carbonate reservoirs. Our results show that the carbonate platform is located between the upper Aptian and lower Albian seismic surfaces. Interpretation of a new surface, called the intra-Albian, was possible via acoustic-impedance (AI) analysis. Our workflow facilitated identification of low AI, high porosity, and best facies areas in structural highs where the most productive wells have been drilled. Facies modeling suggests that intercalation of facies with high and low porosities is connected to shallowing-upward cycles. Finally, several debris facies with low AI and high porosities were identified in an area that could be targeted for new exploration.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Thick marine shales occur in the Wufeng Formation and Longmaxi Formation of Sanquan Town of the Nanchuan District, Chongqing Municipality, which is located on the southeast margin of the Sichuan Basin. However, few details of the characteristics of the Wufeng–Longmaxi shales in this area have been reported. In this study, a well approximately 100 m (∼328 ft) deep was drilled. A high-quality shale (total organic carbon [TOC] 〉2.0 wt. %, clay 〈40%) interval that was approximately 24 m (∼79 ft) thick with an average TOC value of 3.0 wt. % mainly occurs in the Ordovician Wufeng Formation (Katian and Hirnantian) and base of the Silurian Longmaxi Formation (Rhuddanian). Shales with higher TOC values commonly have a higher porosity and specific surface area. Tectonic movements may also have been very important factors that influenced the petrophysical properties of the shales. For example, a detachment layer that resulted from complex tectonic movements is extensive in the Wufeng Formation. The cracks and microcracks in the detachment layer can result in good pore connectivity. Consequently, the detachment layer can be an effective migration pathway. The Longmaxi–Wufeng shales of Sanquan Town are also compared with those of the famous Jiaoye 1 well in the Jiaoshiba shale gas field in the eastern Sichuan Basin. Although the shales in Sanquan Town have considerable shale gas generation potential, the shale gas resource potential in Sanquan Town is probably poor because the escape of shale gas may be accelerated by the detachment layer in destroyed anticlines and synclines.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The ability to accurately predict the probability of fluid migration from depth through existing wells based on known well properties, such as age and depth, would be enormously helpful in understanding how migration pathways develop and the identification of potential migration without extensive field tests. The presence of fluid pathways is an important environmental issue because such pathways allow gas, either naturally occurring methane or sequestered CO〈sub〉2〈/sub〉, to move into the atmosphere. In this paper, we explore the ability of various predictive models to forecast gas migration at existing wells in Alberta, Canada, based upon the characteristics of existing deep wells. Alberta was selected as a case study because of the availability of data in an area that has required wells to be tested for pathway development after rig release since 1995. Wells that do not demonstrate pathway development require no further testing until the well is abandoned. We show that accurately predicting fluid migration requires detailed information on well construction, production, and fluid properties, and even then, the models considered in this study misclassify a large number of wells. This suggests other factors may contribute to pathway formation. Of the models investigated, random forests provide the best results on this data set, correctly identifying 78% of the wells used.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉This study aims to decipher the groundwater status of the parts of Tigray area, Ethiopia using an integrated methodology of remote sensing and geographic information systems (GIS). Digitized vector maps of the study area, that is, geology, land use and/or cover, and drainage, were generated and converted to raster data. The theme weight and class weights were assigned to the raster maps of the respective parameters. Weight age to the layers was assigned using an analytical hierarchy process and further overlay analysis was carried out in the ArcGIS environment to decipher the groundwater resources of the study area.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The present contribution aims for a characterization of microstructure and pore-space distribution of upper Visean Rudov beds, considered the main source rock for conventional oil deposits in the Ukrainian Dneiper–Donets Basin and a prospect for unconventional hydrocarbon production in recent years. Broad ion beam–scanning electron microscopy (SEM) mapping revealed a remarkably heterogeneous microstructure controlled by diagenetic precipitates (Fe/Mg carbonates, albite). Formation of these precipitates is likely triggered by organic matter decomposition and represents an important influencing factor for overall porosity and permeability. Furthermore, shale diagenesis also influences mechanical properties, as suggested by nanoindentation tests. The SEM-visible organic matter porosity is restricted to solid bitumen; although pores less than 2–3 nm in vitrinites of overmature samples are indicated by focused ion beam–SEM results, they cannot be resolved clearly by this method. Pore generation in solid bitumen that likely formed in situ in primary amorphous organic matter already starts at the early oil window in samples from the basinal oil-prone organofacies, whereas most porous solid bitumen at peak oil maturity was interpreted as relicts of primary oil migration, representing an earlier oil phase that predominantly accumulated in quartz-rich layers and became nanoporous during secondary cracking. In the terrestrially dominated transitional to marginal organofacies, pore generation in pyrobitumen resulting from gas generation occurs significantly later and is less intense. Formation of authigenic clay and carbonate minerals within pyrobitumen is likely related to organic acids formed during bitumen decomposition and implies the presence of an aqueous phase even in pores that are apparently filled exclusively with solid bitumen.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The Ahdeb oil field is located in the Mesopotamian Basin of central Iraq within a northwest–southeast-trending anticline. Seven oil-bearing layers exist in the eastern area in the field, but there is only one oil-bearing layer in the western area. This study reveals that the reservoir filling process resulted from the difference in the elements in the petroleum system, the oil generation and migration process, and the formation of the structural trap. Most oils in the field, with pristane/phytane 〈 1 and a high relative abundance of hopanes exceeding C〈sub〉30〈/sub〉, were generated from the Upper Jurassic–Lower Cretaceous Chia Gara Formation, whereas some oils were generated from the Lower Cretaceous Ratawi and Zubair Formations. The mid-Upper Cretaceous reservoirs in the field are composed of lime grainstones, packstones, and wackestones.The main oil accumulation occurred during the Maastrichtian, coinciding with peak oil generation from the Chia Gara Formation with a 50% transformation ratio from organic matter to oil. The reservoirs of the eastern structural trap in the field were filled with large amounts of medium to heavy oils. After the formation of two structural traps in the western area in the mid-Miocene, oils pre-existing in the second layer of the Khasib Formation in the east began migrating toward the structural traps in the west during the late Miocene, as verified by relatively higher 1-/4-methylcarbazole and 1,8-/2,7-dimethycarbazole ratios of oils in the west than that in the east and residual solid bitumen in the east. The strike-slip fault might also have restricted oil or gas migration during the Miocene, limiting oil accumulation in the west.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The success of hydraulic fracturing and increasing use of basin-modeling packages drive the need to understand the effects of hydrocarbon (HC) generation on the mechanical properties of source rocks. A better understanding of relationships among geological, geochemical, and geomechanical parameters can potentially reduce the uncertainties associated with conventional and unconventional prospect evaluation.We present a simulation of microcrack growth based on a three-dimensional source-rock system. Upon thermal maturation, the kerogen transforms into lighter products, most of which are HCs. The generated products exert excessive pore pressure to the system resulting from the effect of volume expansion; this pressure is released through the expansion of pore space and formation of microcracks. Using linear elasticity and linear elastic fracture mechanics, our model calculates microcrack sizes (surface areas, lengths, apertures, and volumes) and the amount of overpressure throughout the maturation process. We validated this model with experimental data from 〈a href="https://pubs.geoscienceworld.org/aapgbull#b20"〉Kobchenko et al. (2011)〈/a〉, and performed sensitivity analysis for both laboratory and geological settings. Much larger microcracks are generated in laboratory settings compared to the subsurface because of the lack of overburden, resulting in secondary porosity over 100 times larger than the original organic porosity and crack lengths obtaining millimeter scale. In contrast, microcracks are much smaller in geological settings because of the presence of significant overburden and stiffer rock frames: the crack apertures are in the submicron regime with a crack length ranging from 100 to 300 μm. The formation of microcracks connects isolated microscale HC pockets, providing pathways for primary migration.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Studies of lacustrine carbonate rocks in continental rifts have received huge interest in recent years because of their great economic value in the South Atlantic. However, most existing facies and tectonosedimentary models for carbonate platforms are based on marine carbonate systems, whereas models for nonmarine systems are scarce. The main aim of this paper is to establish such models and to further our understanding of the hydrocarbon-bearing late synrift Lower Cretaceous carbonate successions of the Campos Basin, Brazil. This paper is based on a proximal to distal industrial data set of three-dimensional (3-D) seismic, cores, and well logs from the Coqueiros Formation (Coquina), southern Campos Basin. The dominant carbonate facies in the Coqueiros Formation are mollusk-rich grainstones, rudstones, and floatstones, which form the main reservoir facies. The 3-D seismic interpretations show an oblique extensional rift system, characterized by a series of grabens, half grabens, accommodation zones, and horsts oriented northeast–southwest to north–northeast-south–southwest. Three tectonic domains are recognized based on structural style, stretching factors, and subsidence rates as well as facies and different types of lacustrine carbonate platforms. Proximal rift margin areas are characterized by a series of half grabens with footwall and hanging-wall dip slopes of shallow lacustrine carbonates and fluviodeltaic mixed carbonate and siliciclastic deposits in marginal, hanging-wall basins. Central areas are carbonate rich with platforms established over horst blocks surrounded by deeper-water carbonate facies. Distal areas have the highest amount of stretching and subsidence and accumulate the thickest carbonate successions over a template of buried horsts and grabens. The entire carbonate succession underlies a thick layer of Aptian salt, which forms the seal to this prolific hydrocarbon system.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The uppermost Middle Triassic Leikoupo Formation in the western Sichuan Basin of China has recently been shown to host as much as 5.3 tcf (1.5 × 10〈sup〉12〈/sup〉 m〈sup〉3〈/sup〉) of natural gas resources. The reservoir rocks, composed mainly of microbially derived dolomudstone (e.g., thrombolites and stromatolites), are characterized by low porosity (〈8%) and permeability (〈0.001 to 10 md). The limestone is commonly tight and not of reservoir quality because of abundant meteoric calcite cementation, whereas the dolostone has various types of pores dominated by solution-enlarged pores and vugs, microbial framework pores, and micropores. Breccias are well developed in places, probably because of dissolution of underlying evaporites (e.g., anhydrite) by an influx of low-salinity fluids (e.g., freshwater and seawater) during an early burial stage. Early dolomitization created micropores in the dolomudstone, and subsequent diagenetic events were dominated by calcite, dolomite, quartz cementation, pyrite replacement, compaction, fracturing, and development of stylolites. Localized hydrothermal activity has been evidenced by high homogenization temperatures (∼160°C–200°C) obtained from fluid inclusions in fracture-filling cements. Bacterial sulfate reduction probably resulted in H〈sub〉2〈/sub〉S generation, pyrite precipitation, and solution-enlarged pore and vug formation, whereas part of the current H〈sub〉2〈/sub〉S in these reservoirs may have been sourced from thermochemical sulfate reduction or an underlying formation (e.g., the Feixiangguan Formation). Development of microfractures and associated micropores was probably the final diagenetic event, which improved pore interconnectivity. This study confirms the effect of diagenesis on the development of a microbial dolomudstone reservoir, which may be applicable to other similar microbial carbonate reservoirs elsewhere, for example, Middle Triassic sections of the Tethys region and offshore Brazil.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Clinoforms, the basic large-scale architectural form within which sediments are stored and eventually fed down depositional dip in clastic wedges, exist in many shapes and sizes. Understanding how they form, evolve, and degrade is critical to understanding how transport mechanisms affect the shelf margin and sediment partitioning and distribution, and their implications on the presence of a working petroleum system. The Neogene stratigraphic succession of the Taranaki Basin in New Zealand contains clinoform packages that display a variety of architectures well imaged on seismic data. Quantitative characterization of this interval was performed to unravel the processes by which clinoforms evolve under the influence of tectonic- and isostatic-driven subsidence, sea-level change, and sediment supply fluctuations. Nine different clinoform packages were identified on the basis of changes in their seismic stratigraphic characteristics. Two-dimensional stratigraphic forward modeling was used to conduct a sensitivity analysis and determine the relative importance of different geologic controls on their genesis. Our results show that during the early to late Pliocene, clinoform architectures were influenced by the opening of a back-arc rifting structure in the Taranaki Basin (northern graben), which controlled sediment redistribution and partitioning. At the same time, a drop in global sea level allowed sediment bypass to distal parts of the basin. During the late Pliocene, changes in the Australian–Pacific subduction zone forced rapid uplifting of the Southern Alps, generating a significant increase in sediment supply. Model simulations suggest that clinoform architectures during the late Pliocene were controlled by this increase in sediment supply and associated loading.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉A detailed, rock-based investigation of three Upper Cretaceous Eagle Ford Group cores situated behind, at, and downdip of the Lower Cretaceous Stuart City paleoreef-shelf margin in south Texas was conducted to understand stratigraphic, sedimentological, and geochemical relationships across this buried shelf margin. An understanding of how the Eagle Ford Group lithofacies vary across the paleoreef-shelf margin is currently lacking. We therefore examined a dip section of three cores across the antecedent shelf margin and delineated seven Eagle Ford lithofacies: (1) massive argillaceous mudstone, (2) massive to laminated foraminiferal lime wackestone, (3) radiolarian and foraminiferal dolomitic to lime packstone, (4) massive to bioturbated skeletal lime wackestone, (5) laminated foraminiferal lime packstone, (6) laminated inoceramid and foraminiferal lime grainstone, and (7) massive to bioturbated claystone. A basinward decrease in calcite from 60% to 48% is accompanied by an increase in clay minerals from 12% to 20%. The low-relief raised rim of the older, buried Stuart City paleoshelf margin may have acted as a barrier, dividing the Eagle Ford Group into two sedimentological systems: (1) a restricted drowned shelf to the north, and (2) an open-marine basinal setting to the south. The lower to upper Cenomanian Eagle Ford strata on the drowned shelf are cyclic and enriched in molybdenum, suggesting anoxic to euxinic water masses. The anoxic, open-marine, basinward strata are less cyclical and have a lower molybdenum (compared with the drowned shelf) content. Ash beds and gravity-flow deposits are rare south of the margin. A depositional model was constructed of the lower and upper Eagle Ford formations.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Predicting the lateral distribution of petroleum play elements (reservoirs, source rocks, and seals) requires basic understanding of regional basin evolution and depositional history. In remote areas where little data are available or where the basins have undergone episodes of tectonic deformation, this understanding relies on integrated analysis of the plate tectonic framework and the resulting paleogeography. The Arctic has experienced several episodes of tectonic deformation, which fundamentally changed the basin configuration and patterns of sediment routing. Here, we present a set of paleogeographic maps highlighting these changes during the Triassic–Paleogene. In the Triassic, the Arctic was characterized by a central restricted basin, which predominantly received clastic input from the Polar Urals and Arctic Canada. The Alaskan and Siberian passive margins received clastics from continent-scale drainage systems extending into the North American craton and the central Asian fold belt, respectively. In the Jurassic, the region was dominated by rifting as the central Arctic landmass rifted away from Laurentia. In the Early Cretaceous, the northern margin of the Barents Sea underwent regional uplift resulting in new provenance areas shedding sediments southward. Compression along the Pacific margin formed continuous topography and high sediment input to the Canada Basin during the Late Cretaceous. Regression in the Canada Basin continued in the Paleogene when major rift–tip deltas formed. This overview of Arctic paleogeography demonstrates the complexity of this overall data-poor area and shows the need for integrated, regional models to understand sediment routing and stratigraphic development in such areas.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉The purpose of this study is to deconstruct the relationship between the Leaf River anticline and the preglacial bedrock paleotopography at the eastern terminus of the Plum River Fault Zone in Ogle County, Illinois, using a geostatistical approach. The contour maps derived from the elevation models provided detailed depictions of the ancient bedrock landscape and subsurface structure in the study area. The Leaf River anticline is interpreted to be a component of hanging-wall anticline at the terminus of the Plum River Fault Zone. The topographic high created by the anticline controlled local drainage and led to the development of the Leaf River paleovalley prior to the Pleistocene. The catastrophic failure of an ice damn during the Illinois glacial episode carved a glacial spillway into the north flank of the Leaf River anticline that interfaced with a tributary of the Leaf River paleovalley. This rerouted the preglacial drainage network and permanently diverted the ancient Rock River to its modern-day position. Ultimately, the subsurface geometry of the Leaf River anticline and its relationship to the local bedrock paleotopography were revealed by the elevation models. The position and development of the Leaf River paleovalley and glacial spillway interpreted in this study aligned with the regional interpretations for the evolution of the ancient bedrock landscape established in prior works. However, this study revealed that the Leaf River anticline and, by association, the terminus of the Plum River Fault Zone extend farther east into the region than indicated by prior works.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉In the last decade, production of shale gas has tremendously increased, and the need for local pre-exploitation baseline data on dissolved natural gas in aquifers has been stressed. This study investigated the origin of hydrocarbons naturally present in shallow aquifers of the Saint-Édouard area (Québec, eastern Canada), where the underlying Utica Shale is known to contain important gas resources that have not yet been exploited. Groundwater and shallow bedrock gas samples were collected and analyzed for isotopic composition of alkanes (δ〈sup〉13〈/sup〉C and δ〈sup〉2〈/sup〉H〈sub〉C1–C3〈/sub〉), dissolved inorganic carbon (δ〈sup〉13〈/sup〉C〈sub〉DIC〈/sub〉), and radiocarbon in methane and DIC (〈sup〉14〈/sup〉C〈sub〉DIC〈/sub〉, 〈sup〉14〈/sup〉C〈sub〉CH4〈/sub〉). This multi-isotope approach proved enlightening, and results revealed that (1) most of the methane in the region is of microbial origin; (2) partial contribution of thermogenic gas occurs in 15% of the wells; (3) processes such as late-stage methanogenesis and methane oxidation are responsible for ambiguous methane isotopic compositions; and (4) both microbial and thermogenic gas originate from the shallow bedrock aquifer, with the exception of one sample likely coming from deeper units. The thick succession of shales overlying the Utica Shale thus appears to act as an effective migration barrier for the shallow aquifers. However, evidence of upward migration of old brines near major fault zones indicates that these may serve as a preferential migration pathway over a certain depth but most likely no more than approximately 200–500 m (∼650–1640 ft). The geochemical framework presented here will hopefully be useful in other research projects, especially when conventional indicators of natural gas origin provide ambiguous results.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉Urbanization modifies the natural water cycle. In this study, a weighted-rating multicriteria analysis was adopted to quantify the runoff index and to assess the impact of urbanization on the water cycle. The considered parameters are (1) slope, (2) permeability of soil, and (3) rainfall. Using the land use map, a runoff risk map was established. The approach was applied to Manouba catchment. The main results revealed that between 2004 and 2014, the area with a high runoff index increased from 32% to 39%. The runoff risk increased; in 2004, the high class covered 18% of the watershed area. This value became 30% in 2014. Results demonstrate that urbanization affects hydrological processes. This method is appropriate in other similar watersheds to estimate the runoff index.〈/span〉

Beschreibung: 〈span〉〈div〉ABSTRACT〈/div〉To better understand controls on the origin and evolution of brackish groundwater, the hydrogeochemistry of brackish groundwaters was studied within the Triassic Dockum Group across the Midland Basin in Texas. The suitability of Dockum Aquifer water for use in hydraulic fracturing fluid was examined because the area overlies the largest and most productive tight oil province in the United States. Groundwater generally flows southward and eastward across the basin. Transmissivities indicate that water yield from the Dockum Aquifer is mixed. Higher salinity (up to ∼100 g/L), group I water is found mainly in the center and western parts of the basin; chemistry of these meteoric waters is controlled by water–rock interaction with salinity increasing along its flow path via dissolution of halite and anhydrite, followed by salinity-enhanced carbonate dissolution and/or cation release from clays. Along the down-gradient basin margins, lower salinity (〈7.5 g/L), group II waters of various ion compositions are more commonly found. Group II waters are also meteoric but from local recharge including downward flow from the Edwards–Trinity or other aquifers. Despite having lower salinity, the water in the down-gradient southern and eastern margins of the basin can exceed acceptable SO〈sub〉4〈/sub〉 limits for cross-linked gel fluids. Generally, the majority of the water in the basin is suitable for use with slick-water hydraulic fracturing. Findings from this research provide important information on the complex controls on the chemistry of brackish groundwater and their potential beneficial uses in the oil and gas industry.〈/span〉

Beschreibung: This article examines the social and environmental costs of living in the mineral age, wherein contemporary global livelihoods depend almost completely on the extraction of mineral resources. Owing to the logic of extractivism—the rapid and widespread removal of resources for exchange in global capitalist markets—both developed and developing countries are inextricably entangled in pursuing resource extraction as a means of sustaining current lifestyles as well as a key mechanism for promoting socioeconomic development. The past 15 years has seen a massive expansion of mineral resource extraction as many developing countries liberalized their mining sectors, allowing foreign capital and mining companies onto the lands of peasant farmers and indigenous people. This mining expansion has also facilitated the rise of artisanal and small-scale mining (ASM). Transformations in livelihoods and corporate practices as well as the environmental impacts and social conflicts wrought by mining are the central foci of this article.

Beschreibung: This article is positioned at the intersection of linguistic, medical, and psychological anthropology and reviews scholarship on the communicative processes that constitute moral/ethical care. Varying notions of care have become a leitmotif in efforts to include the analysis of agency and creativity in discussions of the lived experience of marginalization. Understandings of care have in common an emphasis on relationality and activity: Communicative activities of care both constitute and are made relevant by morally/ethically framed relationships with others and oneself. Embodied communication is central in both care activities and the constitution of moral/ethical care. From a phenomenological standpoint, communicative activities of care are simultaneously social action and embodied experience. This article reviews three key themes: ( a) the embodied linguistic constitution of care, ( b) the performance of care, and ( c) exclusion from care. Together, these themes reveal common moral/ethical–aesthetic processes that are shared across diverse social and cultural contexts.

Beschreibung: Crop foraging or crop raiding concerns wildlife foraging and farmers’ reactions and responses to it. To understand crop foraging and its value to wildlife or its implications for humans requires a cross-disciplinary approach that considers the behavior and ecology of wild animals engaging in this behavior; the types and levels of competition for resources between people and wildlife; people's perceptions of and attitudes toward wildlife, including animals that forage on crops; and discourse about animals and their behaviors and how these discourses can be used for expressing dissent and distress about other social conflicts. So, to understand and respond to conflicts about crop damage, we need to look beyond what people lose, i.e., crop loss and economic equivalence, and focus more on what people say about wildlife and why they say it.

Beschreibung: Null hypothesis significance testing (NHST) is the most common statistical framework used by scientists, including archaeologists. Owing to increasing dissatisfaction, however, Bayesian inference has become an alternative to these methods. In this article, we review the application of Bayesian statistics to archaeology. We begin with a simple example to demonstrate the differences in applying NHST and Bayesian inference to an archaeological problem. Next, we formally define NHST and Bayesian inference, provide a brief historical overview of their development, and discuss the advantages and limitations of each method. A review of Bayesian inference and archaeology follows, highlighting the applications of Bayesian methods to chronological, bioarchaeological, zooarchaeological, ceramic, lithic, and spatial analyses. We close by considering the future applications of Bayesian statistics to archaeological research.

Beschreibung: Anthropologists have sustained a varied and active engagement with ethics throughout the field's history. In light of this long-standing engagement, what marks the distinctiveness of the current ethical turn? To think in Foucauldian terms, ethics/morality now looms large precisely because it has been problematized. Although there has been a recent outpouring of work on ethics, and a widely shared concern to move beyond overly collectivist accounts, much is nascent. Debates and schools of thought are still emerging. In this review article, we explore several resonate streams of disquiet or inspiration within the discipline that have generated new lines of inquiry. These include ( a) emerging debates and confusion around the use of basic terms such as “ethics” and “morality” and their role in debates over ordinary ethics, ( b) articulations of an anthropological virtue ethics (and the Foucault effect), ( c) increasingly sophisticated treatments of moral experience informed by philosophical phenomenology, and ( d) reinvigorated considerations of the political as connected to ethical life.

Beschreibung: This article examines anthropological approaches to fiction reading. It asks why the field of literary anthropology remains largely disinvested of ethnographic work on literary cultures and how that field might approach the study of literature and reading ethnographically. The issue of the creative agency of fiction readers is explored in the context of what it means to ask anthropological questions of literature, which includes the challenge of speaking back to dominant approaches grounded in forms of critical analysis. Finally, the article looks to recent work in the anthropology of Christianity on Bible reading and engagements with biblical characters to open up new questions about the relationship between fiction reading and temporal regimes.

Beschreibung: The practice of human biology requires the negotiation of a range of ethical issues, including the politics of race and indigeneity, the appropriate use of research materials, and the relationship between researchers and those people from whose bodies they seek to gain knowledge. Grounding my discussion in a history of the field, I discuss key ethical turning points that have shaped the present. These include the field's complex historical relationship to race and colonialism and the implications this relationship has for research, including the needs and desires of Indigenous peoples. This review demonstrates that human biology has been a crucible for many of the most complex ethical issues facing anthropology and allied practices of biomedicine and life science. Its future success as a field is inextricable from its practitioners’ ability to adapt in ways that foster the trust and engagement of those humans whose bodies constitute the basis for their knowledge making.

Beschreibung: This article offers insight into the meanings of the unprecedented political potential of humor in the early twenty-first century by discussing three parodic forms of contemporary political humor: carnivalesque politics, parodic reworkings of political discourses, and political protests and satirical activism. Revealing how political parody both produces ambiguity and hinges on it, the article proposes a shift in attention from its effects and capacity to promote or hinder a political change, and from the domination versus resistance binary, toward ambivalent political subjectivities that unfold in the production and consumption of political parody. The ambiguity of political parody, its reflexivity, and its capacity to build or reconfigure affective communities are workings of political humor that enable individuals to embrace their own involvement and vulnerability and the ambiguous and unpredictable moral consequences of their complex positioning as an authentic and potentially productive form of engaging with political reality.

Beschreibung: Starting from a recent flash of reflexive illumination experienced as a member of a dissertation committee, this act of (re-)constructive retrospection recalls the principal forces, experiences, and individuals that shaped my career as a linguistic anthropologist and turned my interests toward poetics, performance, language ideology, and remediation. Retracing my steps—sometimes halting, sometimes headlong—along the winding path that I have followed makes clear the degree to which my career has depended on the generous and energizing influence of my mentors, teachers, and colleagues, but also on the frustrating roadblocks placed in my way by less generous and understanding figures that led me to turn toward what proved to be far more productive directions. This reflexive process has also made clearer to me than ever before how strongly my career has been affected by the shifting conditions imposed by the political economy of higher education as I made my way in academe.

Beschreibung: Since its enactment over five decades ago, the National Historic Preservation Act (NHPA) and the organizations, policies, and regulations implementing it have strongly influenced how archaeology is conducted in the United States. The NHPA created a national network of archaeologists in government agencies. This network reviews the possible impact on important archaeological resources of tens of thousands of public projects planned each year. These reviews often include investigations, of which there have been millions. The archaeological profession has shifted from one oriented mainly on academic research and teaching to one focused on field investigations, planning, resource management, public outreach, and resource protection, bundled under the term cultural resource management (CRM). Since 1966, growth has produced good outcomes as well as some troubling developments. Current and new challenges include avoiding lock-step, overly bureaucratic procedures and finding the financial, professional, and technical resources, as well as political support, to build on the achievements so far.

Beschreibung: Recent years have witnessed burgeoning interest in interspecies relations and multispecies ethnography. This review explores what such perspectives bring to long-standing anthropological attention to agrarian worlds. Considering why so much recent scholarship only minimally engages with longer disciplinary traditions found within ecological and environmental anthropology and ethnobotany, the review examines continuities and discontinuities across these different modes of attending to interspecies relationships. From here, it explores how contemporary scholarship renews anthropological attention to questions of domestication, relatedness, agency, and personhood and how it charts new ground by engaging theories of biopolitics, biocapital, biosemiotics, and plant ontologies. While noting that recent work has distinctive theoretical preoccupations, the review concludes by suggesting that fruitful possibilities lie in working with, and across, established and emergent anthropologies of the agrarian.

Beschreibung: Conservation genetics is a branch of conservation biology that uses molecular data to assist in the conservation and management of imperiled populations, subspecies, and species. In this review, I examine conservation action plans (CAPs)—instrumental documents designed to influence conservation policy—for selected primate species. I use the information contained in CAPs as a means to guide this review. The primary genetics-based topics that are mentioned in CAPs are genetic connectivity, inbreeding, and subspecies/species delimitation. I discuss these topics as well as historical demographic inference and hybridization using examples from wild primate species to illustrate the myriad ways in which genetics can assist in conservation efforts. I also discuss some recent technological advances such as genomic capture techniques and the potential to do molecular work in remote locations.

Beschreibung: Ethics has abandoned its niche status to become a shared concern across archaeology. The appraisal of the sociopolitical context of archaeological practice since the 1980s has forced the discipline to take issue with the expanding array of ethical questions raised by work with living people. Thus, the original foci on the archaeological record, conservation, and scientific standards, which are behind most deontological codes, have been largely transcended and even challenged. In this line, this review emphasizes philosophical and political aspects over practical ones and examines some pressing ethical concerns that are related to archaeology's greater involvement with contemporary communities, political controversies, and social demands; discussion includes ethical responses to the indigenous critique, the benefits and risks of applied archaeology, the responsibilities of archaeologists in conflict and postconflict situations, vernacular digging and collecting practices, development-led archaeology, heritage, and the ethics of things.

Beschreibung: Microfluidics has proven to be a key tool in quantitative biological research. The C. elegans research community in particular has developed a variety of microfluidic platforms to investigate sensory systems, development, aging, and physiology of the nematode. Critical for the growth of this field, however, has been the implementation of concurrent advanced microscopy, hardware, and software technologies that enable the discovery of novel biology. In this review, we highlight recent innovations in microfluidic platforms used for assaying C. elegans and discuss the novel technological approaches and analytic strategies required for these systems. We conclude that platforms that provide analytical frameworks for assaying specific biological mechanisms and those that take full advantage of integrated technologies to extract high-value quantitative information from worm assays are most likely to move the field forward.

Beschreibung: Biosensors represent biomimetic analytical tools for addressing increasing needs in medical diagnosis, environmental monitoring, security, and biodefense. Nevertheless, widespread real-world applications of biosensors remain challenging due to limitations of performance, including sensitivity, specificity, speed, and reproducibility. In this review, we present a DNA nanotechnology-enabled interfacial engineering approach for improving the performance of biosensors. We first introduce the main challenges of the biosensing interfaces, especially under the context of controlling the DNA interfacial assembly. We then summarize recent progress in DNA nanotechnology and efforts to harness DNA nanostructures to engineer various biological interfaces, with a particular focus on the use of framework nucleic acids. We also discuss the implementation of biosensors to detect physiologically relevant nucleic acids, proteins, small molecules, ions, and other biomarkers. This review highlights promising applications of DNA nanotechnology in interfacial engineering for biosensors and related areas.

Beschreibung: Incorporating functionality to atomic force microscopy (AFM) to obtain physical and chemical information has always been a strong focus in AFM research. Modifying AFM probes with specific molecules permits accessibility of chemical information via specific reactions and interactions. Fundamental understanding of molecular processes at the solid/liquid interface with high spatial resolution is essential to many emerging research areas. Nanoscale electrochemical imaging has emerged as a complementary technique to advanced AFM techniques, providing information on electrochemical interfacial processes. While this review presents a brief introduction to advanced AFM imaging modes, such as multiparametric AFM and topography recognition imaging, the main focus herein is on electrochemical imaging via hybrid AFM-scanning electrochemical microscopy. Recent applications and the challenges associated with such nanoelectrochemical imaging strategies are presented.

Beschreibung: The creation of a pharmacokinetic (PK) curve, which follows the plasma concentration of an administered drug as a function of time, is a critical aspect of the drug development process and includes such information as the drug's bioavailability, clearance, and elimination half-life. Prior to a drug of interest gaining clearance for use in human clinical trials, research is performed during the preclinical stages to establish drug safety and dosing metrics from data obtained from the PK studies. Both in vivo animal models and in vitro platforms have limitations in predicting human reaction to a drug due to differences in species and associated simplifications, respectively. As a result, in silico experiments using computer simulation have been implemented to accurately predict PK parameters in human studies. This review assesses these three approaches (in vitro, in vivo, and in silico) when establishing PK parameters and evaluates the potential for in silico studies to be the future gold standard of PK preclinical studies.

Beschreibung: In this review, we summarize recent advances in nanoscale electrochemistry, including the use of nanoparticles, carbon nanomaterials, and nanowires. Exciting developments are reported for nanoscale redox cycling devices, which can chemically amplify signal readout. We also discuss promising high-frequency techniques such as nanocapacitive CMOS sensor arrays or heterodyning. In addition, we review electrochemical microreactors for use in (drug) synthesis, biocatalysis, water treatment, or to electrochemically degrade urea for use in a portable artificial kidney. Electrochemical microreactors are also used in combination with mass spectrometry, e.g., to study the mimicry of drug metabolism or to allow electrochemical protein digestion. The review concludes with an outlook on future perspectives in both nanoscale electrochemical sensing and electrochemical microreactors. For sensors, we see a future in wearables and the Internet of Things. In microreactors, a future goal is to monitor the electrochemical conversions more precisely or ultimately in situ by combining other spectroscopic techniques.

Beschreibung: In this review, I explore some of the lines of inquiry that have emerged in anthropology and closely related disciplines around the theme of drugs and gender. The critical research on drugs over the past few decades has tended to focus on how prohibition policies are racialized, which has been important for revealing the injustice and racism found in drug policies and in commonsense notions about drugs and drug use. Drawing from intersectional theorists who have long argued that racial categories are never experienced or imposed as singular identities separate from gender, language, class, and sexuality, I argue in this article that the literature on gender and drugs has struggled with two main interrelated problems: determining ( a) how to understand gender and race together and ( b) how to theorize gender in relation to power when these two factors are often conflated with each other in both popular discourse and theoretical dispositions about the war on drugs.

Beschreibung: Language has long been at the center of kinship studies, where there has been a tendency to see the role of language in terms of nomenclature for labeling preexisting relations. Linguistic anthropologists have turned to the constitutive role of language in the formation of kin relations. People enact kin relations through behaviors that include, but are not limited to, the linguistic. Rather than static grids of terminology, linguistic anthropology finds its empirical object in the reflexive practices of speakers as they construct, reformulate, transform, and sometimes undercut cultural norms for being kin. Taking kinship behaviors that include language to be in dialectical relation to kinship structures, I review recent work that exemplifies linguistic anthropology's pragmatic approach to kinship, from the richness and diversity of kin relations to the possibility of the lack of kin relations as such.

Beschreibung: This review examines precarity through two foci. First, I focus on related terms of the lumpenproletariat and informal economy, each of which have left their mark on the notion of precarity as a bounded historical condition, and its related notion of the precariat, a sociological category of those who find themselves subject to intermittent casual forms of labor. I explore the ways in which these terms offer pictures of politics and the state that are inherited by the term precarity, understood as the predicament of those who live at the juncture of unstable contract labor and a loss of state provisioning. I then turn to the second pole of precarity to chart a tension between asserting a common condition of ontological precarity and the impulse to describe the various ways in which vulnerability appears within forms of life.

Beschreibung: In South America, as elsewhere, development projects have to go through environmental permitting, a component of which is the archaeological assessment of the areas to be impacted. Because such an assessment is paid for by the development companies seeking such a permit, it has come to be known as contract archaeology. Given the accelerated pace of development projects in the region, it is not surprising that contract archaeology has grown exponentially. The academic literature dealing with it and related fields has also witnessed a rapid growth, which this article seeks to review. In doing so, it discusses the literature that accepts and promotes contract archaeology ( a) as a part of environmental permitting; ( b) as the primary stimulus responsible for widening the job market, whose structure has transformed disciplinary practice to a large extent; and ( c) in terms of its relationship with the archaeological record and with heritage education. This article also reviews a growing literature, both supportive and critical, that assesses contract archaeology.

Beschreibung: Sex-biased power structures are common in human and nonhuman primate societies. “Female dominance” is a term applied to a wide range of female-biased power structures. However, the full extent of this variation remains obscure because an adequate vocabulary of power has not been adopted consistently. Female power occurs throughout primates and other animals, even in male-dominant societies, but the legacy of patriarchy persists in primatologists’ use of language and implicit assumptions about intersexual power. While explanations for the occurrence of female power can be accommodated within existing ethological theory, many hypotheses seeking to explain the evolution of female power are narrowly focused on particular taxa. Theories about primate social evolution would benefit from a synthesis of the disparate literature on power, increased emphasis on intersexual social relationships, and comparative studies that include the full behavioral diversity of primates and other mammals.

Beschreibung: Looting and spoliation of archaeological sites represent a known crisis in many parts of the world, and it is widely acknowledged that despite what we know about the scale of site destruction, the reality is worse. Available evidence suggests that the scale and severity of looting are increasing. Legal and ethical remedies exist but have not proven adequate to reduce the impact of looting and antiquities trafficking. This reflects, in part, inadequate resources and uneven enforcement, and also the pressures of rising prices for antiquities, growing market demand, severe economic depression, and lawlessness, particularly in conflict zones. But it also reflects expanding ideological causes for site destruction by others, as well as competing epistemologies and deontological expectations within the discipline itself challenging the site preservation imperative in archaeology. More than ten years ago, a previous review of these topics found the response inadequate; a decade later, matters are worse.

Beschreibung: Field primatologists have ethical responsibilities that extend beyond study subjects to the local human communities living near primate populations and their surrounding ecosystems. In this review, we explore the history of ethical discussions within anthropological primatology and examine the best practices for an ethically engaged primatology that should be followed and role-modeled by primatologists. An increasing number of primates are showing reduced population sizes and are in imminent danger of extinction; thus, we need to carefully consider the ethics of intervening to ensure the survival of remaining populations, the impact of anthropogenic factors (e.g., climate change), and whether long-term field research results in conservation outcomes that consider local human communities. Because best practices change over time as theoretical frameworks and methodological tools advance and scientific goals change, field primatologists must continually reflect on what constitutes ethical practice and consider how research influences the overlapping dimensions of fieldwork: primates, people, and ecosystems.

Beschreibung: The archaeology of the Nazi era is a relatively new field of research. This review addresses motivations and ethical circumstances of such research, as well as the complex relations between archaeological evidence and a variety of other sources, including documents, oral history, and photography. Archaeologists work with two fundamentally different conceptualizations: an objectivist one concerned with recording material remains, for which scale is a prominent issue, and interpretive approaches based on the evocative power of things, in which different degrees of victims’ anonymity play a core role. Other issues involve questions about the possibility of any coherent synthesis of this period. Investigations into the Nazi past also invariably include commemorative politics whose complex development is outlined. An engagement with this time of extremes has wider consequences, posing the question of the role of suffering and desolation in human history as a whole.

Beschreibung: Environmental stress on primate populations can take many forms. Abiotic factors, such as temperature and precipitation, may directly influence the behavior of primates owing to physiological demands of thermoregulation or through indirect influences on vegetation that primates rely on for food. These effects can also scale up to the macro scale, impacting primate distributions and evolution. Primates also encounter stress during interactions within and between species (i.e., biotic interactions). For example, selective pressure from male-perpetrated infanticide can drive the development of female counterstrategies and can impact life-history traits. Predation on primates can modify group size, ranging behavior, and habitat use. Finally, humans have influenced primate populations for millennia. More recently, hunting, habitat disturbance, disease, and climate change have increased in frequency and severity with detrimental impacts on primate populations worldwide. These effects and recent evidence from camera traps emphasize the importance of maintaining protected areas for conserving primate populations.

Beschreibung: This article reviews recent ethnographies of war that shed light on interconnected states of security at home, international military interventions, and hybrid or rhizomic warfare doctrines. I suggest the notion of hybrid peace to explore global implications of these ethnographic perspectives and to ask what it means to inhabit spaces that are constituted by such hybrid warfare. I argue for the usefulness of Schmitt's “nomos of the earth” and his theory of the partisan to conceptualize this condition and bring together different approaches to warfare.

Beschreibung: This article provides an overview of recent scholarship on the language of evangelism and missionization within the anthropology of Christianity. Attention to Christian evangelism and forms of circulation was minimized as scholars worked to distinguish the study of Christianity from the study of colonialism, often treating missionaries and missionization as a prologue to a more central analysis of transformation organized through local people and local cultural change. However, issues of circulation are at the heart of many Christian experiences, especially for those within evangelical, Pentecostal, and charismatic worlds. This research is discussed here in terms of Christian cultures of circulation specifically and of models of communicative circulation more generally. Framing the language of evangelism in terms of circulation allows for the integrated discussion of a wide range of related issues, including work on translation, missionary training practices, and material formations of evangelism.

Beschreibung: The article investigates how consumerism is perceived as an unremarkable part of quotidian existence, as a patriotic duty at various moments, as an indicator of social class, and as a means of semiotic self-fashioning. In consumerism, the tension between the sumptuary restraint on conspicuous consumption, which characterized the early Protestant ethic, and the dependence of capitalism itself on boundless commodity circulation, emerges again and again. I investigate how certain forms of consumerism, relating to excess and improper storage, are reclassified in medical terms. I also investigate modes of strategic consumerism, which try to bridge the gap between producer and consumer, and how certain forms of performative labor are themselves consumed. I close with a few reflections on sites for future study: shopping as a form of underrecognized labor, and an auto-ethnographic turn for academics, inspecting the reach of consumerism into academic practices and universities themselves.

Beschreibung: Since the year 2000, artists have increasingly employed tools, methods, and aesthetics associated with scientific practice to produce forms of art that assert themselves as kinds of experimental and empirical knowledge production parallel to and in critical dialogue with science. Anthropologists, intrigued by the work of art in the age of its technoscientific affiliation, have taken notice. This article discusses bio art, eco art, and surveillance art that have gathered, or might yet reward, anthropological attention, particularly as it might operate as an allied form of cultural critique. We focus on art that takes oceans as its concern, tuning to anthropological interests in translocal connection, climate change, and the politics of the extraterritorial. We end with a call for decolonizing art–science and for an anti-colonial aesthetics of oceanic worlds.

Beschreibung: Beginning some 10,000 years ago, humans began a dramatic alteration in living conditions relating especially to the shift in lifeway from foraging to farming. In addition to the initiation of and increasing focus on the production and consumption of domesticated plant carbohydrates, this revolutionary transformation in diet occasioned a decline in mobility and an increased size and agglomeration of populations in semipermanent or permanent settlements. These changes in life conditions presented an opportunity for increased transmission of pathogenic microbes from host to host, such as those that cause major health threats affecting most of the 7.5 billion members of our species today. This article discusses the bioarchaeology of infectious disease, focusing on tuberculosis, treponematosis, dental caries, and periodontitis, all of which continue to contribute to high levels of morbidity and mortality among the world's populations today.

Beschreibung: We interrogate the many ways that language and food intersect. Food and its uses provide setting and structure for language, just as language and its uses constrain and inform food activities. We illuminate where and how food and language co-occur and how they are dynamically co-constitutive, foregrounding the potential for food-and-language scholarship to contribute to understandings of political economic processes and structures. We organize our review around the mutual production, consumption, and circulation of food and language. We show that the richness of scholarship about consumption (especially around the family meal) has not been matched by research concerning the production of food and language, whereas the co-constituting circulation of food and language contributes to new meanings and values for both. More research is needed to clarify the surging attention to food, which may be motivated by the complex global food system and the speed and ease of mediatization and circulation of food images and ideologies.

Beschreibung: Bringing together ethnographic approaches to childhood, linguistic anthropology, and relational–feminist perspectives on care, this review focuses on the role of children as interactional brokers of care, a role that has been underappreciated. Building from the premise that, through language, children perform a fundamental form of other-oriented care—that of mediating another person's ability to express themselves—this review explores the material, political, moral, and affective dimensions of children's interactional care work. Attention to the interactional–relational aspects of children's caregiving shows the extent to which children are involved in facilitating the circulation of care and enabling community care networks, and it opens up new possibilities for how we conceptualize care: It illuminates the processes through which care practices are organized, negotiated, and enacted at the intersection of the local and the global; it reveals care as a reciprocal, distributed interactional achievement; and it helps us transcend dichotomies that have characterized scholarly thinking about care.

Beschreibung: This review surveys the past 30 years of the anthropology of corporate animal agribusiness, analyzing how various themes embedded in the words of the article's title—industrial, meat, and production—have been taken up by ethnographers of confinement farms and mechanized slaughterhouses. In so doing, it describes how the literature finds the animal life-and-death cycle underlying modern meat to be a hybrid and uneven mixture of industrialisms both old and emerging, at once violent and caring, far-reaching yet incomplete. The review further examines the numerous and distinct ways that scholars have suggested that industrial meat production is an exceptional kind of industrialism: one that requires analytics, ethics, forms of critique, and modes of attention that differ from those developed by studies of other sites of manufacturing.

Beschreibung: One of the most persistent debates in anthropology and related disciplines has been over the relative weight of aggression and competition versus nonaggression and cooperation as drivers of human behavioral evolution. The literature on hunting and gathering societies—past and present—has played a prominent role in these debates. This review compares recent literature from both sides of the argument and evaluates how accurately various authors use or misuse the ethnographic and archaeological research on hunters and gatherers. Whereas some theories provide a very poor fit with the hunter-gatherer evidence, others build their arguments around a much fuller range of the available data. The latter make a convincing case for models of human evolution that place at their center cooperative breeding and child-rearing, as well as management of conflict, flexible land tenure, and balanced gender relations.

Beschreibung: The anthropology of policing draws from a range of intellectual traditions to generate new understandings of the police as an institution and policing as a social practice. This article reviews recent anthropological work on police, situating it in longer-term disciplinary concerns. I begin with the connection between policing and personhood, exploring how the subject–object dynamics of police domination are related to anthropological conceptions of kinship, law, and social control. I then turn to the contribution that anthropological ethnography makes to a critical theory of the relationship between sovereignty, violence, and police power. I conclude by reflecting on the situation of scholarship in our current political environment, suggesting that the anthropological turn to policing is animated, in part, by hope for a better understanding of the nature of moral agency under difficult conditions.

Beschreibung: The performance, field utility, and low cost of lateral flow assays (LFAs) have driven a tremendous shift in global health care practices by enabling diagnostic testing in previously unserved settings. This success has motivated the continued improvement of LFAs through increasingly sophisticated materials and reagents. However, our mechanistic understanding of the underlying processes that drive the informed design of these systems has not received commensurate attention. Here, we review the principles underpinning LFAs and the historical evolution of theory to predict their performance. As this theory is integrated into computational models and becomes testable, the criteria for quantifying performance and validating predictive power are critical. The integration of computational design with LFA development offers a promising and coherent framework to choose from an increasing number of novel materials, techniques, and reagents to deliver the low-cost, high-fidelity assays of the future.

Beschreibung: Mass spectrometry is the science and technology of ions. As such, it is concerned with generating ions, measuring their properties, following their reactions, isolating them, and using them to build and transform materials. Instrumentation is an essential element of these activities, and analytical applications are one driving force. Work from the Aston Laboratories at Purdue University's Department of Chemistry is described here, with an emphasis on accelerated reactions of ions in solution and small-scale synthesis; ion/surface collision processes, including surface-induced dissociation (SID) and ion soft landing; and applications to tissue imaging. Our special interest in chirality and the chemistry behind the origins of life is also featured together with the exciting area of tissue diagnostics.

Beschreibung: Enzymes catalyze a variety of biochemical reactions in the body and, in conjunction with transporters and receptors, control virtually all physiological processes. There is great value in measuring enzyme activity ex vivo and in vivo. Spatial and temporal differences or changes in enzyme activity can be related to a variety of natural and pathological processes. Several analytical approaches have been developed to meet this need. They can be classified broadly as methods either based on artificial substrates, with the goal of creating images of diseased tissue, or based on natural substrates, with the goal of understanding natural processes. This review covers a selection of these methods, including optical, magnetic resonance, mass spectrometry, and physical sampling approaches, with a focus on creative chemistry and method development that make ex vivo and in vivo measurements of enzyme activity possible.

Beschreibung: Verbatim—word for word—is assumed to be a text that faithfully captures and represents a discursive event that took place in time and space, which would otherwise be ephemeral and unrepeatable. In modern societies, verbatim stands in for durable indexicality and materializes the social epistemology of evidence, accountability, and authenticity. Today's ubiquitous presence of recording technologies amplifies the conviction that the production of verbatim as in the conversion, for example, from speech to writing is unmediated and transparently mechanical. Far from being unremarkable, however, the seemingly unmotivated commensurability between original and copy is an ideological function of social reproduction and institutional power. Building on both classic and contemporary linguistic anthropological and sociolinguistic studies of verbatim texts, this review suggests how ethnographically situated studies of verbatim in its production and process open up cogent historical and political analysis of social institutions and relations and of subject formation through the labor of inscription.

Beschreibung: Mobile health technologies offer great promise for reducing healthcare costs and improving patient care. Wearable and implantable technologies are contributing to a transformation in the mobile health era in terms of improving healthcare and health outcomes and providing real-time guidance on improved health management and tracking. In this article, we review the biomedical applications of wearable and implantable medical devices and sensors, ranging from monitoring to prevention of diseases, as well as the materials used in the fabrication of these devices and the standards for wireless medical devices and mobile applications. We conclude by discussing some of the technical challenges in wearable and implantable technology and possible solutions for overcoming these difficulties.

Beschreibung: Medical errors are a major concern in clinical practice, suggesting the need for advanced surgical aids for preoperative planning and rehearsal. Conventionally, CT and MRI scans, as well as 3D visualization techniques, have been utilized as the primary tools for surgical planning. While effective, it would be useful if additional aids could be developed and utilized in particularly complex procedures involving unusual anatomical abnormalities that could benefit from tangible objects providing spatial sense, anatomical accuracy, and tactile feedback. Recent advancements in 3D printing technologies have facilitated the creation of patient-specific organ models with the purpose of providing an effective solution for preoperative planning, rehearsal, and spatiotemporal mapping. Here, we review the state-of-the-art in 3D printed, patient-specific organ models with an emphasis on 3D printing material systems, integrated functionalities, and their corresponding surgical applications and implications. Prior limitations, current progress, and future perspectives in this important area are also broadly discussed.

Beschreibung: Gas cluster ion beams (GCIBs) provide new opportunities for bioimaging and molecular depth profiling with secondary ion mass spectrometry (SIMS). These beams, consisting of clusters containing thousands of particles, initiate desorption of target molecules with high yield and minimal fragmentation. This review emphasizes the unique opportunities for implementing these sources, especially for bioimaging applications. Theoretical aspects of the cluster ion/solid interaction are developed to maximize conditions for successful mass spectrometry. In addition, the history of how GCIBs have become practical laboratory tools is reviewed. Special emphasis is placed on the versatility of these sources, as size, kinetic energy, and chemical composition can be varied easily to maximize lateral resolution, hopefully to less than 1 micron, and to maximize ionization efficiency. Recent examples of bioimaging applications are also presented.

Beschreibung: The sensitivity of nuclear magnetic resonance (NMR) spectroscopy to the local atomic-scale environment offers great potential for the characterization of a diverse range of solid materials. Despite offering more information than its solution-state counterpart, solid-state NMR has not yet achieved a similar level of recognition, owing to the anisotropic interactions that broaden the spectral lines and hinder the extraction of structural information. Here, we describe the methods available to improve the resolution of solid-state NMR spectra and the continuing research in this area. We also highlight areas of exciting new and future development, including recent interest in combining experiment with theoretical calculations, the rise of a range of polarization transfer techniques that provide significant sensitivity enhancements, and the progress of in situ measurements. We demonstrate the detailed information available when studying dynamic and disordered solids and discuss the future applications of solid-state NMR spectroscopy across the chemical sciences.

Beschreibung: Owing to its extreme sensitivity and easy execution, surface-enhanced Raman spectroscopy (SERS) now finds application for a wide variety of problems requiring sensitive and targeted analyte detection. This widespread application has prompted a proliferation of different SERS-based sensors, suggesting the need for a framework to classify existing methods and guide the development of new techniques. After a brief discussion of the general SERS modalities, we classify SERS-based sensors according the origin of the signal. Three major categories emerge from this analysis: surface-affinity strategy, SERS-tag strategy, and probe-mediated strategy. For each case, we describe the mechanism of action, give selected examples, and point out general misconceptions to aid the construction of new devices. We hope this review serves as a useful tutorial guide and helps readers to better classify and design practical and effective SERS-based sensors.

Beschreibung: Measurements of the intracellular state of mammalian cells often require probes or molecules to breach the tightly regulated cell membrane. Mammalian cells have been shown to grow well on vertical nanoscale structures in vitro, going out of their way to reach and tightly wrap the structures. A great deal of research has taken advantage of this interaction to bring probes close to the interface or deliver molecules with increased efficiency or ease. In turn, techniques have been developed to characterize this interface. Here, we endeavor to survey this research with an emphasis on the interface as driven by cellular mechanisms.

Beschreibung: Single-molecule force spectroscopy (SMFS) has been widely applied to study the mechanical unfolding and folding of transmembrane proteins. Here, we review the recent progress in characterizing bacterial and human transmembrane β-barrel proteins by SMFS. First, we describe the mechanical unfolding of transmembrane β-barrels, which follows a general mechanism dictated by the sequential unfolding and extraction of individual β-strands and β-hairpins from membranes. Upon force relaxation, the unfolded polypeptide can insert stepwise into the membrane as single β-strands or β-hairpins to fold as the native β-barrel. The refolding can be followed at a high spatial and temporal resolution, showing that small β-barrels are able to fold without assistance, whereas large and complex β-barrels require chaperone cofactors. Applied in the dynamic mode, SMFS can quantify the kinetic and mechanical properties of single β-hairpins and reveal complementary insight into the membrane protein structure and function relationship. We further outline the challenges that SMFS experiments must overcome for a comprehensive understanding of the folding and function of transmembrane β-barrel proteins.