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  • Nature Publishing Group  (4.717)
  • ELSEVIER SCIENCE BV
  • 2020-2023
  • 2020-2020
  • 2005-2009  (4.718)
  • 2006  (4.718)
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  • 1
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    Effect of cold storage upon eggs of the calaniod copepod Acartia tonsa (Dana) and their offspring (2006)
    ELSEVIER SCIENCE BV
    In:  EPIC3Aquaculture, ELSEVIER SCIENCE BV, 254(1-4), pp. 714-729, ISSN: 0044-8486
    Details
    Publikationsdatum: 2015-06-25
    Beschreibung: For most fish species raised in marine aquaculture, the use of live feeds cannot be replaced by formulated diets. Artemia nauplii and rotifers are still the most commonly used live feeds. A good alternative lies in the use of copepods which could lead to the cultivation of new fish species. Cold stored subitaneous eggs from the continuously cultured calanoid copepod Acartia tonsa were used to investigate the effect of storage upon the viability of the eggs, the development of the copepod community originating from the cold stored eggs. Finally a 3 days snapshot of the egg production of the first generation of females was followed. This was done in order to develop a database usable within copepod dependent hatcheries. The viability of cold stored A. tonsa eggs remained high (〉 70% hatching rate) for 11 months of storage. Generally, the period of storage was observed to decrease the viability (hatching rate) of the eggs and no hatching was observed after twenty months of cold storage. Hatched populations of copepods experienced increased mortality rate with longer storage of the eggs from which they originated. This mortality ranged from 0.035 to 0.13 d− 1 for non-stored (fresh) and 12 months stored eggs, respectively. However, all copepod communities originating from fresh to 12 months stored eggs reached adulthood. Additionally, the egg production from the stored generation was apparently normal and the viability of their eggs was not statistically different when compared to productions from non-stored communities. Contents of total fatty acids decreased during the storage period. Contents of free amino acids were not statistically different for eggs cold stored up to 12 months, but had decreased severely by 20 months. In conclusion, we consider it safe to store the eggs for up to one year at 2–3 °C during which the eggs retain their viability and biochemical composition. Cold storage of calanoid copepod eggs is relevant for aquaculture as inoculum for culturing live food.
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: Article , peerRev
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  • 2
    Digitale Medien
    Digitale Medien
    News In Brief (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1048-1049 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] 200% ethanol boost from Oz sugar University of Queensland (UQ), Australia, molecular geneticist Robert Birch got more than he bargained for when he introduced a bacterial gene into sugarcane to convert sucrose into its high-value isomer, isomaltulose. In fact, the gene encoding sucrose isomerase, ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-1048
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  • 3
    Digitale Medien
    Digitale Medien
    Profile of a bacterial tumor killer (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1484-1485 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Common bacteria, engineered to safely seek out and kill tumors, may well be the next generation of cancer therapeutics. In this issue, Bettegowda et al. report the genome sequence of one such bacterium, Clostridium novyi-NT, which has been engineered to be non-toxic by deleting the major systemic ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1206-1484
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  • 4
    Digitale Medien
    Digitale Medien
    Anti-infective antibodies: finding the path forward (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1491-1493 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] This June, Basel-based Novartis Pharmaceuticals made a first reconnoiter into antimicrobial antibodies in its quest to find new weapons to fight infections. It paid $569 million to acquire NeuTec Pharmaceuticals of Manchester, UK, and its two late-stage products, both antibody fragments ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1206-1491
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  • 5
    Digitale Medien
    Digitale Medien
    Prospects for plant-derived antibacterials (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1504-1507 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The scarcity of disease in wild plants indicates that the success of plant defense mechanisms in combating pathogen infection rivals that of mammalian immune systems. Although there are some interesting parallels between plant and animal defense strategies—for instance, both groups sacrifice ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1206-1504
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  • 6
    Digitale Medien
    Digitale Medien
    Moving goalposts—regulatory oversight of antibacterial drugs (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1515-1519 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The US Food and Drug Administration (FDA) has recently rejected new antibiotics for common infections citing the requirement that the drugs intended to treat non-serious infections prove superior to placebo rather than active controls. With the introduction of more stringent statistical criteria, ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1206-1515
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  • 7
    Digitale Medien
    Digitale Medien
    The business of developing antibacterials (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1521-1528 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] For developers of antibacterial products, this century began very much on the wrong foot. The number of pharmaceutical companies chasing antibiotics continued to drop, few genuinely new antibiotics reached the clinic and investors remained lukewarm toward startups in this sector. But, despite ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1206-1521
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  • 8
    Digitale Medien
    Digitale Medien
    What is a support vector machine? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1565-1567 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] A support vector machine (SVM) is a computer algorithm that learns by example to assign labels to objects. For instance, an SVM can learn to recognize fraudulent credit card activity by examining hundreds or thousands of fraudulent and nonfraudulent credit card activity reports. Alternatively, an ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1206-1565
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  • 9
    Digitale Medien
    Digitale Medien
    The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1573-1580 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Bacteriolytic anti-cancer therapies employ attenuated bacterial strains that selectively proliferate within tumors. Clostridium novyi-NT spores represent one of the most promising of these agents, as they generate potent anti-tumor effects in experimental animals. We have determined the 2.55-Mb ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1256
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  • 10
    Digitale Medien
    Digitale Medien
    Blue fluorescent proteins with enhanced brightness and photostability from a structurally targeted library (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1569-1571 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The utility of blue fluorescent protein (BFP) has been limited by its low quantum yield and rapid photobleaching. A library targeting residues neighboring the chromophore yielded a variant with enhanced quantum yield (0.55 versus 0.34), reduced pH sensitivity and a 40-fold increase in ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1264
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  • 11
    Digitale Medien
    Digitale Medien
    Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1551-1557 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Short cationic amphiphilic peptides with antimicrobial and/or immunomodulatory activities are present in virtually every life form, as an important component of (innate) immune defenses. These host-defense peptides provide a template for two separate classes of antimicrobial drugs. Direct-acting ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1267
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  • 12
    Digitale Medien
    Digitale Medien
    The art of mismanagement (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1300-1300 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Is it possible that ImClone didn't do its homework on Erbitux's ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1106-1300a
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  • 13
    Digitale Medien
    Digitale Medien
    Merck wipes Serono off Swiss biotech map (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1303-1303 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] On the average report card a test score of three out of five would usually draw the comment 'could do better'. The admonishment to try harder was also given by some observers to Darmstadt-based Merck KGaA's surprise €10.6- ($13.2)-billion acquisition of Serono on September 21. Although ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1106-1303
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  • 14
    Digitale Medien
    Digitale Medien
    The protection racket (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1081-1081 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Biotech stocks can be white-knuckle volatile, but there is a way you can profit from, or insure against, such rapid and dramatic price changes. Through put and call options, you may not only make more profits, but also buy and sell 'protection' for your investments (with no need for 'knuckle' ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0906-1081
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  • 15
    Digitale Medien
    Digitale Medien
    Recent patent applications in tissue engineering (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1095-1095 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Recent patent applications in tissue engineering ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0906-1095
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  • 16
    Digitale Medien
    Digitale Medien
    Evidence and anecdotes: an analysis of human gene patenting controversies (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1091-1094 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Gene patenting has attracted intense scrutiny for decades, raising a host of ethical, legal and economic concerns. Much of the policy debate has focused on seemingly quantifiable and practical concerns about the effect of patents on access to useful technologies in the contexts of both research and ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0906-1091
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  • 17
    Digitale Medien
    Digitale Medien
    Lack of correct data format and comparability limits future integrative microarray research (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1322-1323 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: One of the challenges for the future is how to integrate all the DNA microarray data that have been generated and deposited in public databases. We have studied data from two data repositories and identified that only 38% meet necessary quality and data format standards. Our results ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1106-1322
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  • 18
    Digitale Medien
    Digitale Medien
    Artificial sperm and epigenetic reprogramming (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1097-1098 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Of the many differentiated cell types that have been derived in vitro from mouse embryonic stem (ES) cells, among the most intriguing are cells resembling male and female gametes. Such ES cell–derived germ cells have been shown to undergo meiosis to form haploid gametes that can support early ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0906-1097
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  • 19
    Digitale Medien
    Digitale Medien
    Trust, patents and public perceptions: the governance of controversial biotechnology research (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1352-1354 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The increasingly commercial nature of biomedical research is, rightly or not, a reality of the contemporary research environment. The percentage of biomedical research supported by industry continues to grow, and many public funding agencies now encourage industry partnerships. Although links with ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1106-1352
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  • 20
    Digitale Medien
    Digitale Medien
    Engineering the essence of plants (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1359-1361 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Plant-derived 'essential oils' such as terpenoids are widely used in the fragrance and flavor industries. In this issue, Chappell and colleagues describe an approach for engineering plants that produce elevated levels of commercially relevant terpenoids. They co-express both an enzyme that supplies ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1106-1359
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  • 21
    Digitale Medien
    Digitale Medien
    Connecting genes, drugs and diseases (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1365-1366 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The rallying cry of early 21st century biomedical science is that new combinations of genomic, proteomic and bioinformatic research will provide deeper insights into disease mechanisms, novel markers for diagnostics and new molecular targets for therapeutic intervention. DNA and protein microarrays ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1106-1365
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  • 22
    Digitale Medien
    Digitale Medien
    Are we stuck in the standards? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1374-1376 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Trying to make some sense of it all, But I can see that it makes no sense at all, Is it cool to go to sleep on the floor, 'Cause I don't think that I can take anymore Clowns to the left of me, jokers to the right, Here I am, stuck in the middle with you. Joe Egan and Gerry Rafferty There are ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1106-1374
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  • 23
    Digitale Medien
    Digitale Medien
    Corrigendum: Can science resolve the ethical impasse in stem cell research? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1448-1448 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Nat. Biotechnol. 24, 397–400 (2006); published online 29 March 2006; corrected after print 8 November 2006. In the version of this article initially published, on page 399, column 2, paragraph 4, the authors wrongly credited the idea for using cells from nonviable human embryos as an ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1106-1448c
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  • 24
    Digitale Medien
    Digitale Medien
    Compact, universal DNA microarrays to comprehensively determine transcription-factor binding site specificities (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1429-1435 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Transcription factors (TFs) interact with specific DNA regulatory sequences to control gene expression throughout myriad cellular processes. However, the DNA binding specificities of only a small fraction of TFs are sufficiently characterized to predict the sequences that they can and cannot bind. ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1246
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  • 25
    Digitale Medien
    Digitale Medien
    Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell–derived hepatocytes (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1412-1419 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Severe acute liver failure, even when transient, must be treated by transplantation and lifelong immune suppression. Treatment could be improved by bioartificial liver (BAL) support, but this approach is hindered by a shortage of human hepatocytes. To generate an alternative source of cells for BAL ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1257
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  • 26
    Digitale Medien
    Digitale Medien
    Vaccine manufacturing: challenges and solutions (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1377-1383 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The recent influenza vaccine shortages have provided a timely reminder of the tenuous nature of the world's vaccine supply and the potential for manufacturing issues to severely disrupt vital access to important vaccines. The application of new technologies to the discovery, assessment, development ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1261
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  • 27
    Digitale Medien
    Digitale Medien
    Making the most of microarrays (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1039-1039 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] No technology embodies the rise of 'omic' science more than the DNA microarray. First reduced to practice in the early 1990s, it has since undergone numerous iterations, adaptations and refinements to achieve its present status as the platform of choice for massively parallel gene expression ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-S1
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  • 28
    Digitale Medien
    Digitale Medien
    Brazil next biotech trailblazer in Latin America? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1184-1184 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] One year on from the enforcement of Brazil's innovation law, the first national innovation law in Latin America, it has already earned praise from the country's scientific community, especially from that part dealing with applied research in industry and agriculture, with an emphasis on biotech. ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-1184
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  • 29
    Digitale Medien
    Digitale Medien
    Profile: Michael Fernandez (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1188-1188 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] When Michael Fernandez took over as director of the Pew Initiative on Food and Biotechnology (PIFB) in September 2005, his former boss bequeathed to him a lava lamp for his desk. Oddly enough, the lamp had been the prize for a Halloween costume that parodied Fernandez' image as a dapper science ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-1188
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  • 30
    Digitale Medien
    Digitale Medien
    Reactions to Eprex's adverse reactions (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1199-1200 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: In their letter of correspondence “Eprex-associated pure red cell aplasia and leachates” in the June issue (Nat. Biotechnol. 24, 613–614, 2006), Schellekens & Jiskoot discuss what they consider to be flaws in Johnson & Johnson's (J&J; New Brunswick, NJ, ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-1199
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  • 31
    Digitale Medien
    Digitale Medien
    Biotech buybacks—good or bad? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1207-1207 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] When a biotech company succeeds, it can find more cash in the bank than needed for research and development. It may decide to buy back, or repurchase, its own shares. A buyback is neither good nor bad by definition, but may be smart, dumb or bordering on fraudulent. To make you a savvier, more ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-1207
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  • 32
    Digitale Medien
    Digitale Medien
    The art of gene function prediction (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1474-1475 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: Determining the functions of genes and proteins is a central problem in biology, fundamental to understanding the molecular and biochemical processes that sustain health or cause disease, to identifying and validating new drug targets and to developing reliable diagnostics. Recent ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1206-1474
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  • 33
    Digitale Medien
    Digitale Medien
    Putting proteins on the map (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1223-1224 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The emergence of systems biology has led to a demand for quantitative, comprehensive data on all aspects of biological phenomena. Some aspects, such as RNA expression and protein structure, have received much attention, while others, such as protein location, have lagged behind. In this issue, ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-1223
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  • 34
    Digitale Medien
    Digitale Medien
    Deciphering bioplastic production (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1227-1229 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The shift toward sustainable production systems has focused attention on bioplastics, which can be produced by many microorganisms from renewable raw materials. Polyhydroxyalkanoates (PHAs) are natural polyesters synthesized in the form of discrete intracellular granules in abundances that can ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-1227
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  • 35
    Digitale Medien
    Digitale Medien
    Wastewater genomics (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1229-1230 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Wastewater treatment around the world relies largely on microbial ecosystems, yet little is known about the organisms involved. This 'black box' system mediates aerobic and anaerobic processes that diminish high phosphate loads in wastewaters, a process known as enhanced biological phosphate ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-1229
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  • 36
    Digitale Medien
    Digitale Medien
    Corrigendum: ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1033-1033 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Nat. Biotechnol. 24, 841–847 (2006); published online 25 June 2006; corrected after print 25 July 2006 In the print version of this article and the version initially published online, the last sentence of the URLs section in Methods, p.846, reads, “Sequence information regarding the ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-1033a
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  • 37
    Digitale Medien
    Digitale Medien
    Corrigendum: Design of a genome-wide siRNA library using an artificial neural network (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1033-1033 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Nat. Biotechnol. 23, 995–1001 (2005), published online 17 July 2005; corrected after print 25 July 2006 In the Methods section, p. 1,000, col. 2, paragraph 2, the text beginning: “The whole plate was discarded if for any time point...” and ending, “The final data set ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-1033e
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  • 38
    Digitale Medien
    Digitale Medien
    Corrigendum: Dual selection enhances the signaling specificity of a variant of the quorum-sensing transcriptional activator LuxR (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1033-1033 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Nat. Biotechnol. 24, 708–712 (2006); published online 21 May 2006; corrected after print 25 July 2006 In the Methods section, p.711, “Library construction and selection,” line 11 of the print version of this article and the version initially published online, the plates used for ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-1033c
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  • 39
    Digitale Medien
    Digitale Medien
    Inference in Bayesian networks (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 51-53 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] How does one model a simple cell-signaling pathway? Consider a simple example consisting of a stimulant, an extracellular signal, an inhibitor of the signal, a G protein–coupled receptor, a G protein and the cellular response. The stimulant induces production of the extracellular signal in ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0106-51
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  • 40
    Digitale Medien
    Digitale Medien
    Engineering and characterization of a superfolder green fluorescent protein (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 79-88 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Existing variants of green fluorescent protein (GFP) often misfold when expressed as fusions with other proteins. We have generated a robustly folded version of GFP, called 'superfolder' GFP, that folds well even when fused to poorly folded polypeptides. Compared to 'folding reporter' GFP, a ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1172
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  • 41
    Digitale Medien
    Digitale Medien
    Extracellular accumulation of recombinant proteins fused to the carrier protein YebF in Escherichia coli (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 100-104 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Bacterial protein secretion is important in the life cycles of most bacteria, in which it contributes to the formation of pili and flagella and makes available extracellular enzymes to digest polymers for nutritional purposes and toxins to kill host cells in infections of humans, animals and ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1174
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  • 42
    Digitale Medien
    Digitale Medien
    Transgenic crops expressing Bacillus thuringiensis toxins and biological control (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 63-71 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The area devoted to growing transgenic plants expressing insecticidal Cry proteins derived from Bacillus thuringiensis (Bt) is increasing worldwide. A major concern with the adoption of Bt crops is their potential impact on nontarget organisms including biological control organisms. Regulatory ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1180
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  • 43
    Digitale Medien
    Digitale Medien
    Tysabri back on market (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 874-874 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The return of the multiple sclerosis (MS) drug Tysabri (natalizumab) to the US market, sanctioned by the US Food and Drug Administration (FDA) on June 5, and its first-time approval in the EU, announced on June 29, was welcomed by investors. The move should also eventually lead to a clearer ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-874
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  • 44
    Digitale Medien
    Digitale Medien
    Alfimeprase to succeed Genentech's alteplase? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 875-876 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Nuvelo is forging ahead with phase 3 trials on its blood-clot buster enzyme alfimeprase, with results expected early next year. The recombinant enzyme attracted the attention of Bayer Healthcare, which earlier this year signed a $385-million deal for alfimeprase's non-US rights—an ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-875
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  • 45
    Digitale Medien
    Digitale Medien
    Diagnostics investors think positive (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 884-884 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Diagnostics companies have had record fundraising on the public markets over the past few years. Venture capital also expanded last year, raising more than double than in previous years, with $113 million the average quarterly amount raised over the past year compared with only $47 ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-884
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  • 46
    Digitale Medien
    Digitale Medien
    Looking for solid ground along the Critical Path (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 885-887 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Even as the science supporting innovation in drug and device development moves forward, the US agency charged with evaluating the products of that science remains embroiled in battles over resources and even its proper mandate. Indeed, the Food and Drug Administration (FDA, Rockville, MD, USA), ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-885
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  • 47
    Digitale Medien
    Digitale Medien
    Genetic profiteering (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 888-890 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Once the province of clinical genetics units in hospitals and clinics, genetic tests have become a commodity. With the click of a mouse, you can order up tests to find out whether you are a carrier of the cystic fibrosis (CF) gene, prone to cardiovascular disease or a member of an ancient tribe. ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-888
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  • 48
    Digitale Medien
    Digitale Medien
    Automated phosphorylation site mapping (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 1226-1227 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Mass spectrometry (MS) allows the localization of phosphorylated amino acid residues in proteins. Precise annotation of phosphorylation sites is not trivial, however, because of the inherent complexity of most phosphopeptide mass spectra. In this issue, Beausoleil et al. report computational ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1006-1226
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  • 49
    Digitale Medien
    Digitale Medien
    Should we make a fuss? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 899-899 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: In their commentary in the December issue (Nat. Biotechnol. 23, 1479–1480, 2005) Jon Beckwith and Franklin Huang chastise T. H. Morgan for his failure to make a fuss about eugenics in 1915. That year, he gave the Vanuxem Lectures at Princeton University, which were published ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-899a
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  • 50
    Digitale Medien
    Digitale Medien
    Should we make a fuss? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 899-900 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: An endorsement of ethical responsibility in science is difficult to oppose. The challenge, however, often is to ascertain what constitutes an ethical or wise course of action. In their commentary, Beckwith and Huang allude specifically to a “stirring of the scientific ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-899b
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  • 51
    Digitale Medien
    Digitale Medien
    Export signals (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 900-901 
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    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: The letter by Katariina Majander et al. in last year's April issue (Nat. Biotechnol. 23, 475–481, 2005) described the use of a modified flagellar type III secretion system (TTSS) to secrete heterologous polypeptides into the growth medium of Escherichia coli. N-terminal ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-900
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  • 52
    Digitale Medien
    Digitale Medien
    Reply to Export signals (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 901-902 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Katariina Majander et al. respond In contrast to the comments of Gál et al., the aim of our paper was not to address the nature of the secretion signal motif per se but to evaluate the biotechnological potential of the secretion system. We did, however, briefly discuss the three proposed ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-901
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  • 53
    Digitale Medien
    Digitale Medien
    What brown cannot do for you (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 914-916 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Chromogenic stains have been a mainstay as readouts for immunodiagnostics. 'Brown' staining—also known as diaminobenzidine (DAB) chromogenic staining or immunoperoxidase staining—was adopted very early in anatomic pathology and rapidly became the standard for immunohistochemistry in ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-914
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  • 54
    Digitale Medien
    Digitale Medien
    Protein annotation by EBIMed (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 902-903 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: PubMed is the key retrieval engine for Medline abstracts, and its host, the US National Library of Medicine (NLM; Bethesda, Maryland), provides efficient query interfaces. The result of queries is a list of abstracts, in which the most recent documents appear at the top. If the list ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-902
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  • 55
    Digitale Medien
    Digitale Medien
    Cancer biomarkers: a systems approach (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 905-908 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Biomarkers measured in a variety of patient samples, including blood, tissue, urine and cerebrospinal fluid, are used in a diverse array of clinical settings. Although many successful biomarkers have been developed to date, advances in genetics and proteomics promise to usher in a new era of ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-905
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  • 56
    Digitale Medien
    Digitale Medien
    A regulatory perspective on in vitro diagnostics (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 927-929 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] In vitro diagnostics (IVDs) has been an area of considerable innovation over the past decade, transforming the practice of medicine in the process. In the area of cardiovascular care alone, new markers for early cardiac injury and for heart failure have fundamentally changed the way doctors manage ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-927
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  • 57
    Digitale Medien
    Digitale Medien
    Any diamonds in the diagnostic coal? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 930-930 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Although you might have been led to believe there is a 'clear vision' for the molecular diagnostics revolution, in reality the investing picture is much murkier. Revenues haven't produced much profit or free cash flow (and are unlikely to do so anytime soon). And rather than stand-alone diagnostics ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0806-930
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  • 58
    Digitale Medien
    Digitale Medien
    Fishing for cancer models (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 45-46 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Fish have been used as models in cancer research for almost a century because of the strikingly similar histopathological features of fish and human tumors. Despite this agreement, however, very little is known about the correspondence of the molecular mechanisms that drive tumorigenesis in these ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0106-45
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  • 59
    Digitale Medien
    Digitale Medien
    Protein biomarker discovery and validation: the long and uncertain path to clinical utility (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 971-983 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Better biomarkers are urgently needed to improve diagnosis, guide molecularly targeted therapy and monitor activity and therapeutic response across a wide spectrum of disease. Proteomics methods based on mass spectrometry hold special promise for the discovery of novel biomarkers that might form ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1235
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  • 60
    Digitale Medien
    Digitale Medien
    Bioethanol needs biotech now (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 725-725 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The last time biofuels figured prominently on the editorial pages of this journal was July 1996. Back then, we were struck by how many biofuel projects appeared to be “solutions in search of a problem.” Ten years later, a problem has been found. Biofuels, in particular ethanol, are ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-725
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  • 61
    Digitale Medien
    Digitale Medien
    Interest heats up in gastrointestinal space (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 727-728 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] A flurry of investment activity during the first months of 2006 is evidence that some investors are waking up to the untapped market potential of a range of widely occurring gastrointestinal (GI) conditions that are as yet not well served. Companies, however, face difficult challenges because of ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-727
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  • 62
    Digitale Medien
    Digitale Medien
    Irrational exuberance? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 726-726 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] While biotech researchers are stepping up to increase the efficiency and reduce the environmental impact of ethanol production, investors are also doing their bit to get biofuel off the launch pad. No less than Bill Gates, entrepreneur Richard Branson, venture capital guru Vinod Khosla and ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-726
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  • 63
    Digitale Medien
    Digitale Medien
    Pipeline cherrypicking deal yields lucrative return (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 729-729 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Exelixis just presented phase 1 clinical trial data for three new kinase inhibitors at the 2006 American Society of Clinical Oncology annual meeting held in Atlanta, Georgia June 2–3. The compounds are included in a licensing and development deal with GlaxoSmithKline (GSK) that gives the ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-729
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  • 64
    Digitale Medien
    Digitale Medien
    Merck moves into biotech (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 730-730 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] In May, Merck, one of the oldest and stodgiest pharmaceutical companies, entered the biotech arena by announcing its plans to purchase two protein manufacturing firms: GlycoFi for $400 million and Abmaxis for $80 million. Now that even the most traditional pharmaceutical companies are ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-730
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  • 65
    Digitale Medien
    Digitale Medien
    Profile: Elliot Entis (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 735-735 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Anyone who has spent time with Elliot Entis, CEO and cofounder of Aqua Bounty Technologies (ABT), has heard him say that he subscribes to the “pinball theory of life.” That is, when the right people and the right ideas are bouncing around together, the combination eventually results in ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-735
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  • 66
    Digitale Medien
    Digitale Medien
    Ecological risk assessment for Bt crops (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 749-751 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: In their Perspective on commercialized Bacillus thuringiensis (Bt) toxin transgenic crops and biological control in the January issue (Nat. Biotechnol. 24, 63–71, 2006), Jörg Romeis et al. draws some conclusions that do not fully and accurately represent the published ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-749
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  • 67
    Digitale Medien
    Digitale Medien
    Reply to Ecological risk assessment for Bt crops (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 751-753 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Jörg Romeis, Michael Meissle and Franz Bigler respond: Our Perspective compiled available peer-reviewed literature addressing the impact on biological control organisms of transgenic crops that express Cry proteins derived from Bacillus thuringiensis (Bt). The published results were discussed ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-751
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  • 68
    Digitale Medien
    Digitale Medien
    Bonkers about biofuels (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 755-760 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Are biofuels an idea whose time has come? Biotech industry boosters, environmental groups, farmers, automobile manufacturers and even some oil companies say that fuel made from plants, organic waste products and various other forms of biomass is now a feasible proposition. There are even ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-755
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  • 69
    Digitale Medien
    Digitale Medien
    Do cisgenic plants warrant less stringent oversight? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 753-753 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] To the editor: While the debate continues on the appropriate level of regulatory oversight for transgenic plants, we believe there are strong reasons for legislators to differentiate cisgenic from transgenic plants. A cisgenic plant is a crop plant that has been genetically modified with one or ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-753
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  • 70
    Digitale Medien
    Digitale Medien
    Implementing biofuels on a global scale (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 761-764 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The recent establishment of the Regional Greenhouse Gas Initiative, a carbon cap-and-trade strategy to help curb global warming by nine states in the northeast United States, is significant not only because it sharply contrasts with US federal policy but also because it sends a message, rather than ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-761
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  • 71
    Digitale Medien
    Digitale Medien
    Investing in green and white biotech (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 765-767 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Plants use the energy of sunlight to fix atmospheric CO2 into a vast biomass, yet we currently use only a small proportion of this fixed carbon for fuel, fiber and building materials. At least three major factors—rapidly increasing atmospheric CO2 levels, dwindling fossil fuel reserves and ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-765
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  • 72
    Digitale Medien
    Digitale Medien
    The return of the biotech scorecard (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 768-768 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Just like you should go for a health checkup every year, you should also periodically check the vital signs of your investments. There are essentially three steps in checking your stock picks and comparing them with passive investments that mimic the well-known market averages. The first is to ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-768
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  • 73
    Digitale Medien
    Digitale Medien
    Biopharmaceutical benchmarks 2006 (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 769-776 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The past three years have been interesting times for the biopharmaceutical industry. The first biosimilar product—Omnitrope (recombinant human growth hormone (rhGH); Sandoz, Holzkirchen, Germany) for treating growth hormone deficiencies—was approved in both the United States and Europe; ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-769
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  • 74
    Digitale Medien
    Digitale Medien
    Can biofuels finally take center stage? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 777-784 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Biodiesel and ethanol, despite their surging popularity as transportation fuels, barely put a dent in our use of oil. But that could change. The biggest well in biofuels has yet to be tapped—lignocellulose, the woody part of the plant and a potentially abundant source of energy. ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-777
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  • 75
    Digitale Medien
    Digitale Medien
    Recent patent applications in microarrays (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 787-787 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Recent patent applications in microarrays ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-787
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  • 76
    Digitale Medien
    Digitale Medien
    The CREATE Act: increasing costs associated with the biotech industry? (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 785-786 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Academics and governmental agencies express concern that the explosive growth in biotech patenting might hamper successful innovation, technology transfer and commercialization of biotechnological advances for society's use. The prospect of a 'patent thicket' or 'anti-commons' is especially serious ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-785
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  • 77
    Digitale Medien
    Digitale Medien
    New 'omics tools for fission yeast (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 789-790 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Techniques commonly used with fission and budding yeasts, such as genetic analysis and the endogenous tagging of proteins, are often the envy of people working with higher eukaryotes. In this issue, Yoshida and colleagues at the RIKEN Institute in Japan present a long-awaited report on an ORFeome ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-789
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  • 78
    Digitale Medien
    Digitale Medien
    Putting immunoinformatics to the test (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 791-792 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Although invasive pathogens may express thousands of proteins containing millions of potential epitopes, only a small subset of these sequences actually stimulates immunity. Indeed, accurate prediction of epitopes is akin to finding a needle in a haystack. In this issue, Moutaftsi et al. ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-791
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  • 79
    Digitale Medien
    Digitale Medien
    Phage display extends its reach (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 793-794 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] In phage display, a protein of interest is incorporated into the coat of a filamentous bacteriophage of Escherichia coli by genetically fusing it with one of several phage coat proteins. However, because the phage coat is assembled in the periplasm, phage display has been limited to the subset of ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-793
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  • 80
    Digitale Medien
    Digitale Medien
    Drugging the PI3 kinome (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 794-796 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Protein kinases have proved their mettle as drug targets in oncology. The strategy of “drugging the cancer kinome” has led to trastuzumab (Herceptin), targeted to ERBB2/HER2; imatinib (Gleevec), targeted to BRC-ABL, KIT and PDFGR; and gefitinib/erlotinib (Iressa/Tarceva), targeted to ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-794
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  • 81
    Digitale Medien
    Digitale Medien
    RNAi in moderation (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 796-797 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The enthusiasm surrounding RNA interference (RNAi) as a new therapeutic modality has been tempered by a growing awareness of its potential to cause unwanted side effects. RNAi has been found variously to induce 'off-target' gene silencing, to trigger an interferon response leading to global ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-796
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  • 82
    Digitale Medien
    Digitale Medien
    Research Highlights (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 799-799 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Siliconized spider silk What do you get if you cross a cobweb with plankton? The answer is probably something similar to what Kaplan and colleagues have obtained through genetic engineering: hard, crystal-like threads that could be useful in the design and engineering of biomaterials for bone ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0706-799
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  • 83
    Digitale Medien
    Digitale Medien
    Signal sequences directing cotranslational translocation expand the range of proteins amenable to phage display (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 823-831 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Even proteins that fold well in bacteria are frequently displayed poorly on filamentous phages. Low protein presentation on phage might be caused by premature cytoplasmic folding, leading to inefficient translocation into the periplasm. As translocation is an intermediate step in phage assembly, we ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1218
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  • 84
    Digitale Medien
    Digitale Medien
    A consensus epitope prediction approach identifies the breadth of murine T CD8+ -cell responses to vaccinia virus (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 817-819 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The value of predictive algorithms for identifying CD8+ T (TCD8+)-cell epitopes has not been adequately tested experimentally. Here we demonstrate that conventional bioinformatic methods predict the vast majority of TCD8+-cell epitopes derived from vaccinia virus WR strain (VACV-WR) in the H-2b ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1215
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  • 85
    Digitale Medien
    Digitale Medien
    Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 848-851 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Although optical absorption is strongly associated with the physiological status of biological tissue, existing high-resolution optical imaging modalities, including confocal microscopy, two-photon microscopy and optical coherence tomography, do not sense optical absorption directly. ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1220
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  • 86
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    Digitale Medien
    Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 856-863 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Conventional anti-inflammatory strategies induce multiple side effects, highlighting the need for novel targeted therapies. Here we show that knockdown of the basic-region leucine zipper protein, c-Jun, by a catalytic DNA molecule, Dz13, suppresses vascular permeability and transendothelial ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt1225
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  • 87
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    Digitale Medien
    The death spiral (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 594-594 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Every year, Nature Biotechnology publishes a financial survey of the public biotech sector (); this year, for the first time, we also analyze the financial health of that other uncharted universe, private biotech firms (). Throughout biotech's history, few have questioned the wisdom of using the ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-594
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  • 88
    Digitale Medien
    Digitale Medien
    Monoclonals expand into neural disorders (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 595-596 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] In April, Pfizer bought a Genentech spinoff, Rinat Neuroscience, for “close to $500 million dollars,” according to one source. What drew Pfizer's interest to Rinat was its pipeline, in particular, two of its most advanced drugs. Both are monoclonal antibodies that Pfizer hopes to ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-595
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  • 89
    Digitale Medien
    Digitale Medien
    First in class stimulates natural killer cells (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 597-597 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The first ever clinical trial of a therapeutic that binds to natural killer (NK) cell receptors is slated to take place before the year end. Its goal is to harness directly the therapeutic potential of NK cells in the treatment of a wide range of immune-related conditions, including cancers, ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-597
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  • 90
    Digitale Medien
    Digitale Medien
    Reverse mergers attract top-tier biotechs in sluggish IPO market (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 598-599 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Now that valuations and market performance have plummeted, many biotech companies have little chance at an initial public offering (IPO). Some therefore turn to the old trick of doing a reverse merger, as an attractive financing option. Essentially the acquisition of a public company shell by a ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-598
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  • 91
    Digitale Medien
    Digitale Medien
    Private biotech 2004—the numbers (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 635-641 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Around 85% of all healthcare and healthcare-related biotech companies are privately owned, and yet relatively little is known about most of them. This is partly because privately owned companies contribute proportionally little to the overall statistics of the sector: they account for less than 50% ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-635
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  • 92
    Digitale Medien
    Digitale Medien
    Insights into US public biotech sector using patenting trends (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 643-651 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Over the past two decades, biotech firms have played an increasingly important role in the research and development of drugs, technologies and tools. In recent years, a lot of attention has been paid to the role of universities in fostering innovation and technology transfer in biotech in the post ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-643
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  • 93
    Digitale Medien
    Digitale Medien
    Recent patent applications relating to peptide therapeutics (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 656-656 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Recent patent applications relating to peptide therapeutics ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-656
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  • 94
    Digitale Medien
    Digitale Medien
    The patentability of human embryonic stem cells in Europe (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 653-655 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The United States Patent and Trademark Office (USPTO) has, to date, granted 41 patents that claim human embryonic stem (hES) cells in their title and front pages. These include patents on culture methods, differentiated cells derived from hES cells and even hES cells per se. By contrast, the ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-653
    Standort Signatur Erwartet Verfügbarkeit
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  • 95
    Digitale Medien
    Digitale Medien
    Single-cell genomics (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 657-658 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Relatively few bacterial species observed in nature have been grown in pure culture. For the vast majority of bacteria, genome sequencing has been prevented by the inability to obtain cloned populations using standard microbiological techniques. As a result, bacterial genomicists have become ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-657
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  • 96
    Digitale Medien
    Digitale Medien
    RISC control for gene therapy (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 661-662 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] One of the difficulties facing gene therapy is the risk of an immune response against newly introduced transgenes. Although partial success in abrogating such immune responses has been achieved, additional strategies to limit the risk of host-mediated immune rejection will likely be essential. In a ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-661
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  • 97
    Digitale Medien
    Digitale Medien
    The germ of pluripotency (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 663-664 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Robust and reproducible methods for deriving adult pluripotent stem cells would have an immense impact on regenerative medicine. Such cells would circumvent the ethical and technical problems associated with embryonic stem (ES) cells, and the possibility of autologous transplantation would avoid ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-663
    Standort Signatur Erwartet Verfügbarkeit
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  • 98
    Digitale Medien
    Digitale Medien
    Research highlights (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 665-665 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Silence is golden A recent paper in Science describes a new addition to the toolbox of techniques for knocking down gene expression in cultured cells. Mirkin and colleagues study the utility of gold nanoparticles decorated with antisense oligos for silencing a reporter gene in mouse endothelial ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-665
    Standort Signatur Erwartet Verfügbarkeit
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  • 99
    Digitale Medien
    Digitale Medien
    Tools for kinetic modeling of biochemical networks (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 667-672 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] The number of software packages for kinetic modeling of biochemical networks continues to grow. Although most packages share a common core of functionality, the specific capabilities and user interfaces of different packages mean that choosing the best package for a given task is not trivial. We ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-667
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  • 100
    Digitale Medien
    Digitale Medien
    Erratum: Gene prioritization through genomic data fusion (2006)
    [s.l.] : Nature Publishing Group
    Nature biotechnology 24 (2006), S. 719-719 
    Details
    ISSN: 1546-1696
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: [Auszug] Nat. Biotechnol. 24, 537–544 (2006) In the print version of this article and the version originally published online, reference 5 was mistakenly included on page 537, column 2, lines 3, 10 and reference 1 on line 17, and the line “Ouzounis8 and the Prospectr scores from Euan ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/nbt0606-719d
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