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  • PANGAEA  (17.516)
  • Annual Reviews
  • Periodicals Archive Online (PAO)
  • 2000-2004  (18.609)
  • 1980-1984
  • 1935-1939
  • 2004  (18.609)
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  • 2000-2004  (18.609)
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  • 1
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    PANGAEA
    In:  EPIC3Limnol. Oceanogr., 49(2)329., Bremerhaven, PANGAEA, 322
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 2
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    PANGAEA
    In:  EPIC3Geochemical Journal, Vol. 38, pp., Bremerhaven, PANGAEA, pp. 613-621
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 3
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    PANGAEA
    In:  EPIC3Institut für Hydrobiologie und Fischereiwissenschaft, Universität Hamburg., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 4
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    PANGAEA
    In:  EPIC3Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
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  • 5
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    PANGAEA
    In:  EPIC3Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/zip
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  • 6
    Publikationsdatum: 2015-01-06
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 7
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    PANGAEA
    In:  EPIC3GHOST project., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 8
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    PANGAEA
    In:  EPIC3GHOST project., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 9
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    PANGAEA
    In:  EPIC3GHOST project., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 10
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/zip
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  • 11
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    PANGAEA
    In:  EPIC3Mem. National Institute of Polar Research, Special Issue, Bremerhaven, PANGAEA, 58, pp. 196-202
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 12
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    PANGAEA
    In:  EPIC3IRIS 2004 field campaign., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-16
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 13
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    PANGAEA
    In:  EPIC3GreenICE Deliverable D11, Bremerhaven, PANGAEA, 24 p.
    Publikationsdatum: 2019-07-16
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 14
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    PANGAEA
    In:  EPIC3RV LANCE 15/2004 cruise, Bremerhaven, PANGAEA, 21 p.
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 15
    Publikationsdatum: 2019-07-16
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 16
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    PANGAEA
    In:  EPIC3Diplomarbeit der Philosophisch-naturwissenschaftlichen Fakultät (Geographisches Institut) der Universität Bern., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 17
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 18
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    PANGAEA
    In:  EPIC3Research, European Commission, Thematic Programme: Environment and Sustainable Development, Bremerhaven, PANGAEA, 99 p.
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 19
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    PANGAEA
    In:  EPIC3Leibniz Institute of Marine Sciences, Christian-Albrechts-University, Kiel, Bremerhaven, PANGAEA, 50 p.
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 20
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 21
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    PANGAEA
    In:  EPIC3Instituto del Mar del Perú IMARPE., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
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  • 22
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    PANGAEA
    In:  EPIC3Cruise on R/V Lance, Bremerhaven, PANGAEA, 22 p.
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 23
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    PANGAEA
    In:  EPIC3Schmitt, Carolin; Kottmeier, Christoph; Wassermann, Stefanie; Drinkwater, Mark (2004): Atlas of Antarctic sea ice drift, Universität Karlsruhe, European Space Agency, WCRP International Programme for Antarctic Buoys, Forschungszentrum Karlsruhe. The work, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 24
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    PANGAEA
    In:  EPIC3Augustin, Laurent; Barbante, Carlo; Barnes, Piers R F; Barnola, Jean-Marc; Bigler, Matthias; Castellano, Emiliano; Cattani, Olivier; Chappellaz, Jérôme A; Dahl-Jensen, Dorthe; Delmonte, Barbara; Dreyfus, Gabrielle; Durand, Gael; Falourd, Sonia; Fischer, H, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 25
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    PANGAEA
    In:  EPIC3Augustin, Laurent; Barbante, Carlo; Barnes, Piers R F; Barnola, Jean-Marc; Bigler, Matthias; Castellano, Emiliano; Cattani, Olivier; Chappellaz, Jérôme A; Dahl-Jensen, Dorthe; Delmonte, Barbara; Dreyfus, Gabrielle; Durand, Gael; Falourd, Sonia; Fischer, H, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 26
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    PANGAEA
    In:  EPIC3Cruise Report MD139 - ASSEMBLAGE-1, Research, European Commission, Thematic Programme: Environment and Sustainable Development., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 27
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    PANGAEA
    In:  EPIC3Cruise Report MD139 - ASSEMBLAGE-1, Research, European Commission, Thematic Programme: Environment and Sustainable Development., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 28
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    PANGAEA
    In:  EPIC3Cruise Report MD139 - ASSEMBLAGE-1, Research, European Commission, Thematic Programme: Environment and Sustainable Development., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 29
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    PANGAEA
    In:  EPIC3Lambrecht, Anja; Kipfstuhl, Josef; Wilhelms, Frank; Miller, Heinz (2004): Visual stratigraphy of the EDML ice core with a linescanner., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 30
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 31
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 32
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 33
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 34
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 35
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 36
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 37
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 38
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    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 39
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    PANGAEA
    In:  EPIC3Universidad Nacional Agraria La Molina., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 40
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    PANGAEA
    In:  EPIC3Forschungsschiff / Research Vessel METEOR : Äquatorial- und Süd-Atlantik / Equatorial and South Atlantic ; Reise Nr. 62 / Cruise No. 62 ; 24.06.2004 30.12.2004 ; Fahrtabschnitte METEOR Reise Nr. 62, Bremerhaven, PANGAEA, 4 p.
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 41
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 42
    Publikationsdatum: 2018-08-10
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 43
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 44
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 45
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 46
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    PANGAEA
    In:  EPIC3Unpublished Cruise report, Research Institute for Exploitation of the Sea (IFREMER), Brest, France, Bremerhaven, PANGAEA, pp. 1-7
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 47
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    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 48
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    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 49
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    PANGAEA
    In:  EPIC3Albrecht-von-Haller-Institut für Pflanzenwissenschaften, Universität Göttingen, Germany, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 50
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    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 51
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    PANGAEA
    In:  EPIC3AREX2004 cruise of the R.V. Oceania, Bremerhaven, PANGAEA, 13 p.
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 52
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 53
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 54
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 55
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
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  • 56
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    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
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  • 57
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 58
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 59
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 60
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3Alfred Wegener Institute for Polar and Marine Research, Bremerhaven, Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 61
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 62
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 63
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 64
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremehaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 65
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 66
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 67
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3FIELAX Gesellschaft für wissenschaftliche Datenverarbeitung mbH, Bremerhaven., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 68
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    Unbekannt
    PANGAEA
    In:  EPIC3Acta Palaeobotanica, Bremerhaven, PANGAEA, 44(2), pp. 195-215
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 69
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 70
    facet.materialart.
    Unbekannt
    PANGAEA
    In:  EPIC3GHOST project., Bremerhaven, PANGAEA
    Publikationsdatum: 2019-07-17
    Repository-Name: EPIC Alfred Wegener Institut
    Materialart: PANGAEA Documentation , notRev
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 71
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biophysics and Biomolecular Structure 33 (2004), S. 387-413 
    ISSN: 1056-8700
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Physik
    Notizen: Residual dipolar couplings (RDCs) have recently emerged as a new tool in nuclear magnetic resonance (NMR) with which to study macromolecular structure and function in a solution environment. RDCs are complementary to the more conventional use of NOEs to provide structural information. While NOEs are local-distance restraints, RDCs provide long-range orientational information. RDCs are now widely utilized in structure calculations. Increasingly, they are being used in novel applications to address complex issues in structural biology such as the accurate determination of the global structure of oligonucleotides and the relative orientation of protein domains. This review briefly describes the theory and methods for obtaining RDCs and then describes the range of biological applications where RDCs have been used.
    Materialart: Digitale Medien
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  • 72
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biophysics and Biomolecular Structure 33 (2004), S. 269-295 
    ISSN: 1056-8700
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Physik
    Notizen: Views of how cell membranes are organized are presently changing. The lipid bilayer that constitutes these membranes is no longer understood to be a homogeneous fluid. Instead, lipid assemblies, termed rafts, have been introduced to provide fluid platforms that segregate membrane components and dynamically compartmentalize membranes. These assemblies are thought to be composed mainly of sphingolipids and cholesterol in the outer leaflet, somehow connected to domains of unknown composition in the inner leaflet. Specific classes of proteins are associated with the rafts. This review critically analyzes what is known of phase behavior and liquid-liquid immiscibility in model systems and compares these data with what is known of domain formation in cell membranes.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 73
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 20 (2004), S. 593-618 
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: During brain development, neurons migrate great distances from proliferative zones to generate the cortical gray matter. A series of studies has identified genes that are critical for migration and targeting of neurons to specific brain regions. These genes encode three basic groups of proteins and produce three distinct phenotypes. The first group encodes cytoskeletal molecules and produces graded and dosage-dependent effects, with a significant amount of functional redundancy. This group also appears to play important roles during the initiation and ongoing progression of neuronal movement. The second group encodes signaling molecules for which homozygous mutations lead to an inverted cortex. In addition, this group is responsible for movement of neurons through anatomic boundaries to specific cortical layers. The third group encodes enzymatic regulators of glycosylation and appears to delineate where neuronal migration will arrest. There is significant cross-talk among these different groups of molecules, suggesting possible points of pathway convergence.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 74
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 20 (2004), S. 725-757 
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: The principles underlying regeneration in planarians have been explored for over 100 years through surgical manipulations and cellular observations. Planarian regeneration involves the generation of new tissue at the wound site via cell proliferation (blastema formation), and the remodeling of pre-existing tissues to restore symmetry and proportion (morphallaxis). Because blastemas do not replace all tissues following most types of injuries, both blastema formation and morphallaxis are needed for complete regeneration. Here we discuss a proliferative cell population, the neoblasts, that is central to the regenerative capacities of planarians. Neoblasts may be a totipotent stem-cell population capable of generating essentially every cell type in the adult animal, including themselves. The population properties of the neoblasts and their descendants still await careful elucidation. We identify the types of structures produced by blastemas on a variety of wound surfaces, the principles guiding the reorganization of pre-existing tissues, and the manner in which scale and cell number proportions between body regions are restored during regeneration.
    Materialart: Digitale Medien
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  • 75
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 20 (2004), S. 481-504 
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: Plant membrane trafficking shares many features with other eukaryotic organisms, including the machinery for vesicle formation and fusion. However, the plant endomembrane system lacks an ER-Golgi intermediate compartment, has numerous Golgi stacks and several types of vacuoles, and forms a transient compartment during cell division. ER-Golgi trafficking involves bulk flow and efficient recycling of H/KDEL-bearing proteins. Sorting in the Golgi stacks separates bulk flow to the plasma membrane from receptor-mediated trafficking to the lytic vacuole. Cargo for the protein storage vacuole is delivered from the endoplasmic reticulum (ER), cis-Golgi, and trans-Golgi. Endocytosis includes recycling of plasma membrane proteins from early endosomes. Late endosomes appear identical with the multivesiculate prevacuolar compartment that lies on the Golgi-vacuole trafficking pathway. In dividing cells, homotypic fusion of Golgi-derived vesicles forms the cell plate, which expands laterally by targeted vesicle fusion at its margin, eventually fusing with the plasma membrane.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 76
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 20 (2004), S. 285-308 
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: We review the current status of research in dorsal-ventral (D-V) patterning in vertebrates. Emphasis is placed on recent work on Xenopus, which provides a paradigm for vertebrate development based on a rich heritage of experimental embryology. D-V patterning starts much earlier than previously thought, under the influence of a dorsal nuclear -Catenin signal. At mid-blastula two signaling centers are present on the dorsal side: The prospective neuroectoderm expresses bone morphogenetic protein (BMP) antagonists, and the future dorsal endoderm secretes Nodal-related mesoderm-inducing factors. When dorsal mesoderm is formed at gastrula, a cocktail of growth factor antagonists is secreted by the Spemann organizer and further patterns the embryo. A ventral gastrula signaling center opposes the actions of the dorsal organizer, and another set of secreted antagonists is produced ventrally under the control of BMP4. The early dorsal -Catenin signal inhibits BMP expression at the transcriptional level and promotes expression of secreted BMP antagonists in the prospective central nervous system (CNS). In the absence of mesoderm, expression of Chordin and Noggin in ectoderm is required for anterior CNS formation. FGF (fibroblast growth factor) and IGF (insulin-like growth factor) signals are also potent neural inducers. Neural induction by anti-BMPs such as Chordin requires mitogen-activated protein kinase (MAPK) activation mediated by FGF and IGF. These multiple signals can be integrated at the level of Smad1. Phosphorylation by BMP receptor stimulates Smad1 transcriptional activity, whereas phosphorylation by MAPK has the opposite effect. Neural tissue is formed only at very low levels of activity of BMP-transducing Smads, which require the combination of both low BMP levels and high MAPK signals. Many of the molecular players that regulate D-V patterning via regulation of BMP signaling have been conserved between Drosophila and the vertebrates.
    Materialart: Digitale Medien
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  • 77
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 20 (2004), S. 455-480 
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: Macrophages are essential modulators of lipid metabolism and the innate immune system. Lipid and inflammatory pathways induced in activated macrophages are central to the pathogenesis of human diseases including atherosclerosis. Recent work has shown that expression of genes involved in lipid uptake and cholesterol efflux in macrophages is controlled by peroxisome proliferator-activated receptors (PPARs) and liver X receptors (LXRs). Other studies have implicated these same receptors in the modulation of macrophage inflammatory gene expression. Together, these observations position PPARs and LXRs at the crossroads of lipid metabolism and inflammation and suggest that these receptors may serve to integrate these pathways in the control of macrophage gene expression. In this review, we summarize recent work that has advanced our understanding of the roles of PPARs and LXRs in macrophage biology and discuss the implication of these results for cardiovascular physiology and disease.
    Materialart: Digitale Medien
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  • 78
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 20 (2004), S. 87-123 
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: The endoplasmic reticulum (ER) and the Golgi comprise the first two steps in protein secretion. Vesicular carriers mediate a continuous flux of proteins and lipids between these compartments, reflecting the transport of newly synthesized proteins out of the ER and the retrieval of escaped ER residents and vesicle machinery. Anterograde and retrograde transport is mediated by distinct sets of cytosolic coat proteins, the COPII and COPI coats, respectively, which act on the membrane to capture cargo proteins into nascent vesicles. We review the mechanisms that govern coat recruitment to the membrane, cargo capture into a transport vesicle, and accurate delivery to the target organelle.
    Materialart: Digitale Medien
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  • 79
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 20 (2004), S. 427-453 
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: The one-cell Caenorhabditis elegans embryo divides asymmetrically into a larger and smaller blastomere, each with a different fate. How does such asymmetry arise? The sperm-supplied centrosome establishes an axis of polarity in the embryo that is transduced into the establishment of anterior and posterior cortical domains. These cortical domains define the polarity of the embryo, acting upstream of the PAR proteins. The PAR proteins, in turn, determine the subsequent segregation of fate determinants and the plane of cell division. We address how cortical asymmetry could be established, relying on data from C. elegans and other polarized cells, as well as from applicable models. We discuss how cortical polarity influences spindle position to accomplish an asymmetric division, presenting the current models of spindle orientation and anaphase spindle displacement. We focus on asymmetric cell division as a function of the actin and microtubule cytoskeletons, emphasizing the cell biology of polarity.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 80
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 20 (2004), S. 695-723 
    ISSN: 1081-0706
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie , Medizin
    Notizen: The study of the epithelium of the adult mammalian intestine touches upon many modern aspects of biology. The epithelium is in a constant dialogue with the underlying mesenchyme to control stem cell activity, proliferation in transit-amplifying compartments, lineage commitment, terminal differentiation and, ultimately, cell death. There are spatially distinct compartments dedicated to each of these events. The Wnt, TGF-beta, BMP, Notch, and Par polarity pathways are the major players in homeostatic control of the adult epithelium. Several hereditary cancer syndromes deregulate these same signaling cascades through mutational (in)activation. Moreover, these mutations often also occur in sporadic tumors. Thus symmetry exists between the roles that these signaling pathways play in physiology and in cancer of the intestine. This is particularly evident for the Wnt/APC pathway, for which the mammalian intestine has become one of the most-studied paradigms. Here, we integrate recent knowledge of the molecular inner workings of the prototype signaling cascades with their specific roles in intestinal epithelial homeostasis and in neoplastic transformation of the epithelium.
    Materialart: Digitale Medien
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  • 81
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Materials Research 34 (2004), S. 83-122 
    ISSN: 1531-7331
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Maschinenbau
    Notizen: Semiconductor nanowires and nanotubes exhibit novel electronic and optical properties owing to their unique structural one-dimensionality and possible quantum confinement effects in two dimensions. With a broad selection of compositions and band structures, these one-dimensional semiconductor nanostructures are considered to be the critical components in a wide range of potential nanoscale device applications. To fully exploit these one-dimensional nanostructures, current research has focused on rational synthetic control of one-dimensional nanoscale building blocks, novel properties characterization and device fabrication based on nanowire building blocks, and integration of nanowire elements into complex functional architectures. Significant progress has been made in a few short years. This review highlights the recent advances in the field, using work from this laboratory for illustration. The understanding of general nanocrystal growth mechanisms serves as the foundation for the rational synthesis of semiconductor heterostructures in one dimension. Availability of these high-quality semiconductor nanostructures allows systematic structural-property correlation investigations, particularly of a size- and dimensionality-controlled nature. Novel properties including nanowire microcavity lasing, phonon transport, interfacial stability and chemical sensing are surveyed.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 82
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Materials Research 34 (2004), S. 1-40 
    ISSN: 1531-7331
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Maschinenbau
    Notizen: Highly strained semiconductors grow epitaxially on mismatched substrates in the Stranski-Krastanow growth mode, wherein islands are formed after a few monolayers of layer-by-layer growth. Elastic relaxation on the facet edges, renormalization of the surface energy of the facets, and interaction between neighboring islands via the substrate are the driving forces for self-organized growth. The dimensions of the defect-free islands are of the order lambaB, the de Broglie wavelength, and provide three-dimensional quantum confinement of carriers. Self-organized In(Ga)As/GaAs quantum dots, or quantum boxes, are grown by molecular beam expitaxy (MBE) or metal-organic vapor phase epitaxy (MOVPE) on GaAs, InP, and other substrates and are being incorporated in microelectronic and opto-electronic devices. The use of strain to produce self-organized quantum dots has now become a well-accepted approach and is widely used in III-V semiconductors and other material systems. Much progress has been made in the area of growth, where focus has been on size control, and on optical characterization, where the goal has been the application to lasers and detectors. The unique carrier dynamics in the dots, characterized by femtosecond pump-probe spectroscopy, has led to novel device applications. This article reviews the growth and electronic properties of InGaAs quantum dots and the characteristics of interband and intersublevel lasers and detectors and modulation devices.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 83
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Materials Research 34 (2004), S. 123-150 
    ISSN: 1531-7331
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Maschinenbau
    Notizen: Carbon nanotubes functionalized with biological molecules (such as protein peptides and nucleic acids) show great potential for application in bioengineering and nanotechnology. Fundamental understanding, description, and regulation of such bio-nano-systems will ultimately lead to a new generation of integrated systems that combine unique properties of the carbon nanotube (CNT) with biological recognition capabilities. In this review, we describe recent advances in understanding the interactions between deoxyribonucleic acids (DNA) and CNT, as well as relevant simulation techniques. We also review progress in simulating DNA noncovalent interactions with CNTs in an aqueous environment. Molecular dynamics simulations indicate that DNA molecules may be encapsulated inside or wrap around CNT owing to van der Waals attraction between DNA and CNT. We focus on the dynamics and energetics of DNA encapsulation inside nanotubes and discuss the mechanism of encapsulation and the effects of nanotube size, nanotube end-group, DNA base sequence, solvent temperature and pressure on the encapsulation process. Finally, we discuss the likely impact of DNA encapsulation on bioengineering and nanotechnology, as well as other potential applications.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 84
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Materials Research 34 (2004), S. 279-314 
    ISSN: 1531-7331
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Maschinenbau
    Notizen: Modeling and simulation are becoming increasingly accepted components of materials research. In this review we discuss application of modeling and simulation in the developing field of biomaterials. To restrict the discussion somewhat, we focus primarily on the structure and properties of biomaterials and do not discuss biochemical or biomedical applications. We start with a discussion of how atomistic-level simulation can be used to study molecules and collections of molecules. We then focus on mesoscale simulations of structure and properties, followed by a brief review of continuum-scale approaches. We end with some thoughts on the future of modeling and simulation in biomaterials applications.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 85
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 35 (2004), S. 557-581 
    ISSN: 1543-592X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: We review the evidence of regime shifts in terrestrial and aquatic environments in relation to resilience of complex adaptive ecosystems and the functional roles of biological diversity in this context. The evidence reveals that the likelihood of regime shifts may increase when humans reduce resilience by such actions as removing response diversity, removing whole functional groups of species, or removing whole trophic levels; impacting on ecosystems via emissions of waste and pollutants and climate change; and altering the magnitude, frequency, and duration of disturbance regimes. The combined and often synergistic effects of those pressures can make ecosystems more vulnerable to changes that previously could be absorbed. As a consequence, ecosystems may suddenly shift from desired to less desired states in their capacity to generate ecosystem services. Active adaptive management and governance of resilience will be required to sustain desired ecosystem states and transform degraded ecosystems into fundamentally new and more desirable configurations.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 86
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 35 (2004), S. 285-322 
    ISSN: 1543-592X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Studies of plant and animal assemblages from both the terrestrial and the marine fossil records reveal persistence for extensive periods of geological time, sometimes millions of years. Persistence does not require lack of change or the absence of variation from one occurrence of the assemblage to the next in geological time. It does, however, imply that assemblage composition is bounded and that variation occurs within those bounds. The principal cause for these patterns appears to be species-, and perhaps clade-level, environmental fidelity that results in long-term tracking of physical conditions. Other factors that influence persistent recurrence of assemblages are historical, biogeographic effects, the "law of large numbers," niche differentiation, and biotic interactions. Much research needs to be done in this area, and greater uniformity is needed in the approaches to studying the problem. However, great potential also exists for enhanced interaction between paleoecology and neoecology in understanding spatiotemporal complexity of ecological dynamics.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 87
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 35 (2004), S. 523-556 
    ISSN: 1543-592X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: The evolutionary succession of marine photoautotrophs began with the origin of photosynthesis in the Archean Eon, perhaps as early as 3.8 billion years ago. Since that time, Earth's atmosphere, continents, and oceans have undergone substantial cyclic and secular physical, chemical, and biological changes that selected for different phytoplankton taxa. Early in the history of eukaryotic algae, between 1.6 and 1.2 billion years ago, an evolutionary schism gave rise to "green" (chlorophyll b-containing) and "red" (chlorophyll c-containing) plastid groups. Members of the "green" plastid line were important constituents of Neoproterozoic and Paleozoic oceans, and, ultimately, one green clade colonized land. By the mid-Mesozoic, the green line had become ecologically less important in the oceans. In its place, three groups of chlorophyll c-containing eukaryotes, the dinoflagellates, coccolithophorids, and diatoms, began evolutionary trajectories that have culminated in ecological dominance in the contemporary oceans. Breakup of the supercontinent Pangea, continental shelf flooding, and changes in ocean redox chemistry may all have contributed to this evolutionary transition. At the same time, the evolution of these modern eukaryotic taxa has influenced both the structure of marine food webs and global biogeochemical cycles.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 88
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 35 (2004), S. 199-227 
    ISSN: 1543-592X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Species are routinely used as fundamental units of analysis in biogeography, ecology, macroevolution, and conservation biology. A large literature focuses on defining species conceptually, but until recently little attention has been given to the issue of empirically delimiting species. Researchers confronted with the task of delimiting species in nature are often unsure which method(s) is (are) most appropriate for their system and data type collected. Here, we review twelve of these methods organized into two general categories of tree- and nontree-based approaches. We also summarize the relevant biological properties of species amenable to empirical evaluation, the classes of data required, and some of the strengths and limitations of each method. We conclude that all methods will sometimes fail to delimit species boundaries properly or will give conflicting results, and that virtually all methods require researchers to make qualitative judgments. These facts, coupled with the fuzzy nature of species boundaries, require an eclectic approach to delimiting species and caution against the reliance on any single data set or method when delimiting species. No one definition has as yet satisfied all naturalists; yet every naturalist knows vaguely what he means when he speaks of a species. Darwin (1859/1964)
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  • 89
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    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 35 (2004), S. 175-197 
    ISSN: 1543-592X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Mutualisms occur when interactions between species produce reciprocal benefits. However, the outcome of these interactions frequently shifts from positive, to neutral, to negative, depending on the environmental and community context, and indirect effects commonly produce unexpected mutualisms that have community-wide consequences. The dynamic, and context dependent, nature of mutualisms can transform consumers, competitors, and parasites into mutualists, even while they consume, compete with, or parasitize their partner species. These dynamic, and often diffuse, mutualisms strongly affect community organization and ecosystem processes, but the historic focus on pairwise interactions decoupled from their more complex community context has obscured their importance. In aquatic systems, mutualisms commonly support ecosystem-defining foundation species, underlie energy and nutrient dynamics within and between ecosystems, and provide mechanisms by which species can rapidly adjust to ecological variance. Mutualism is as important as competition, predation, and physical disturbance in determining community structure, and its impact needs to be adequately incorporated into community theory.
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  • 90
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 35 (2004), S. 467-490 
    ISSN: 1543-592X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Spatial synchrony refers to coincident changes in the abundance or other time-varying characteristics of geographically disjunct populations. This phenomenon has been documented in the dynamics of species representing a variety of taxa and ecological roles. Synchrony may arise from three primary mechanisms:(a) dispersal among populations, reducing the size of relatively large populations and increasing relatively small ones; (b) congruent dependence of population dynamics on a synchronous exogenous random factor such as temperature or rainfall, a phenomenon known as the "Moran effect"; and (c) trophic interactions with populations of other species that are themselves spatially synchronous or mobile. Identification of the causes of synchrony is often difficult. In addition to intraspecific synchrony, there are many examples of synchrony among populations of different species, the causes of which are similarly complex and difficult to identify. Furthermore, some populations may exhibit complex spatial dynamics such as spiral waves and chaos. Statistical tests based on phase coherence and/or time-lagged spatial correlation are required to characterize these more complex patterns of spatial dynamics fully.
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  • 91
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 35 (2004), S. 435-466 
    ISSN: 1543-592X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Ecologists and evolutionary biologists are broadly interested in how the interactions among organisms influence their abundance, distribution, phenotypes, and genotypic composition. Recently, we have seen a growing appreciation of how multispecies interactions can act synergistically or antagonistically to alter the ecological and evolutionary outcomes of interactions in ways that differ fundamentally from outcomes predicted by pairwise interactions. Here, we review the evidence for criteria identified to detect community-based, diffuse coevolution. These criteria include (a) the presence of genetic correlations between traits involved in multiple interactions, (b) interactions with one species that alter the likelihood or intensity of interactions with other species, and (c) nonadditive combined effects of multiple interactors. In addition, we review the evidence that multispecies interactions have demographic consequences for populations, as well as evolutionary consequences. Finally, we explore the experimental and analytical techniques, and their limitations, used in the study of multispecies interactions. Throughout, we discuss areas in particular need of future research.
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  • 92
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 35 (2004), S. 375-403 
    ISSN: 1543-592X
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Floral evolution has often been associated with differences in pollination syndromes. Recently, this conceptual structure has been criticized on the grounds that flowers attract a broader spectrum of visitors than one might expect based on their syndromes and that flowers often diverge without excluding one type of pollinator in favor of another. Despite these criticisms, we show that pollination syndromes provide great utility in understanding the mechanisms of floral diversification. Our conclusions are based on the importance of organizing pollinators into functional groups according to presumed similarities in the selection pressures they exert. Furthermore, functional groups vary widely in their effectiveness as pollinators for particular plant species. Thus, although a plant may be visited by several functional groups, the relative selective pressures they exert will likely be very different. We discuss various methods of documenting selection on floral traits. Our review of the literature indicates overwhelming evidence that functional groups exert different selection pressures on floral traits. We also discuss the gaps in our knowledge of the mechanisms that underlie the evolution of pollination syndromes. In particular, we need more information about the relative importance of specific traits in pollination shifts, about what selective factors favor shifts between functional groups, about whether selection acts on traits independently or in combination, and about the role of history in pollination-syndrome evolution.
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  • 93
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Astronomy and Astrophysics 42 (2004), S. 211-273 
    ISSN: 0066-4146
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Physik
    Notizen: Turbulence affects the structure and motions of nearly all temperature and density regimes in the interstellar gas. This two-part review summarizes the observations, theory, and simulations of interstellar turbulence and their implications for many fields of astrophysics. The first part begins with diagnostics for turbulence that have been applied to the cool interstellar medium and highlights their main results. The energy sources for interstellar turbulence are then summarized along with numerical estimates for their power input. Supernovae and superbubbles dominate the total power, but many other sources spanning a large range of scales, from swing-amplified gravitational instabilities to cosmic ray streaming, all contribute in some way. Turbulence theory is considered in detail, including the basic fluid equations, solenoidal and compressible modes, global inviscid quadratic invariants, scaling arguments for the power spectrum, phenomenological models for the scaling of higher-order structure functions, the direction and locality of energy transfer and cascade, velocity probability distributions, and turbulent pressure. We emphasize expected differences between incompressible and compressible turbulence. Theories of magnetic turbulence on scales smaller than the collision mean free path are included, as are theories of magnetohydrodynamic turbulence and their various proposals for power spectra. Numerical simulations of interstellar turbulence are reviewed. Models have reproduced the basic features of the observed scaling relations, predicted fast decay rates for supersonic MHD turbulence, and derived probability distribution functions for density. Thermal instabilities and thermal phases have a new interpretation in a supersonically turbulent medium. Large-scale models with various combinations of self-gravity, magnetic fields, supernovae, and star formation are beginning to resemble the observed interstellar medium in morphology and statistical properties. The role of self-gravity in turbulent gas evolution is clarified, leading to new paradigms for the formation of star clusters, the stellar mass function, the origin of stellar rotation and binary stars, and the effects of magnetic fields. The review ends with a reflection on the progress that has been made in our understanding of the interstellar medium and offers a list of outstanding problems.
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  • 94
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Astronomy and Astrophysics 42 (2004), S. 169-210 
    ISSN: 0066-4146
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Physik
    Notizen: Observation of cooling neutron stars can potentially provide information about the states of matter at supernuclear densities. We review physical properties important for cooling such as neutrino emission processes and superfluidity in the stellar interior, surface envelopes of light elements owing to accretion of matter, and strong surface magnetic fields. The neutrino processes include the modified Urca process and the direct Urca process for nucleons and exotic states of matter, such as a pion condensate, kaon condensate, or quark matter. The dependence of theoretical cooling curves on physical input and observations of thermal radiation from isolated neutron stars are described. The comparison of observation and theory leads to a unified interpretation in terms of three characteristic types of neutron stars: high-mass stars, which cool primarily by some version of the direct Urca process; low-mass stars, which cool via slower processes; and medium-mass stars, which have an intermediate behavior. The related problem of thermal states of transiently accreting neutron stars with deep crustal burning of accreted matter is discussed in connection with observations of soft X-ray transients. Observations imply that some stars cool more rapidly than can be explained on the basis of nonsuperfluid neutron star models cooling via the modified Urca process, whereas other star cool less rapidly. We describe possible theoretical models that are consistent with observations.
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  • 95
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Astronomy and Astrophysics 42 (2004), S. 79-118 
    ISSN: 0066-4146
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Physik
    Notizen: We review recent theoretical results on the formation of the first stars in the universe, and emphasize related open questions. In particular, we discuss the initial conditions for Population III star formation, as given by variants of the cold dark matter cosmology. Numerical simulations have investigated the collapse and the fragmentation of metal-free gas, showing that the first stars were predominantly very massive. The exact determination of the stellar masses, and the precise form of the primordial initial mass function, is still hampered by our limited understanding of the accretion physics and the protostellar feedback effects. We address the importance of heavy elements in bringing about the transition from an early star formation mode dominated by massive stars to the familiar mode dominated by low-mass stars at later times. We show how complementary observations, both at high redshifts and in our local cosmic neighborhood, can be utilized to probe the first epoch of star formation.
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  • 96
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Astronomy and Astrophysics 42 (2004), S. 685-721 
    ISSN: 0066-4146
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Physik
    Notizen: Until the late 1990s the rich Hyades and the sparse UMa clusters were the only coeval, comoving concentrations of stars known within 60 pc of Earth. Both are hundreds of millions of years old. Then beginning in the late 1990s the TW Hydrae Association, the Tucana/Horologium Association, the beta Pictoris Moving Group, and the AB Doradus Moving Group were identified within ~60 pc of Earth, and the eta Chamaeleontis cluster was found at 97 pc. These young groups (ages 8-50 Myr), along with other nearby, young stars, will enable imaging and spectroscopic studies of the origin and early evolution of planetary systems.
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  • 97
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Astronomy and Astrophysics 42 (2004), S. 317-364 
    ISSN: 0066-4146
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Physik
    Notizen: GRS 1915+105-the first stellar-scale, highly relativistic jet source identified-is a key system for our understanding of the disc-jet coupling in accreting black hole systems. Comprehending the coupling between inflow and outflow in this source not only is important for X-ray binary systems but has a broader relevance for studies of active galactic nuclei and gamma-ray bursts. In this paper, we present a detailed review of the observational properties of the system, as established in the decade since its discovery. We attempt to place it in context by a detailed comparison with other sources, and construct a simple model for the disc-jet coupling, which may be more widely applicable to accreting black hole systems.
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  • 98
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 38 (2004), S. 203-232 
    ISSN: 0066-4197
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Completion of the cell cycle requires the temporal and spatial coordination of chromosome segregation with mitotic spindle disassembly and cytokinesis. In budding yeast, the protein phosphatase Cdc14 is a key regulator of these late mitotic events. Here, we review the functions of Cdc14 and how this phosphatase is regulated to accomplish the coupling of mitotic processes. We also discuss the function and regulation of Cdc14 in other eukaryotes, emphasizing conserved features.
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  • 99
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    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 38 (2004), S. 771-791 
    ISSN: 0066-4197
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Recent advances in DNA-sequencing technologies have made available an enormous resource of data for the study of bacterial genomes. The broad sample of complete genomes currently available allows us to look at variation in the gross features and characteristics of genomes while the detail of the sequences reveal some of the mechanisms by which these genomes evolve. This review aims to describe bacterial genome structures according to current knowledge and proposed hypotheses. We also describe examples where mechanisms of genome evolution have acted in the adaptation of bacterial species to particular niches.
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  • 100
    Digitale Medien
    Digitale Medien
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Genetics 38 (2004), S. 749-770 
    ISSN: 0066-4197
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Biologie
    Notizen: Ribosomal RNA transcription is the rate-limiting step in ribosome synthesis in bacteria and has been investigated intensely for over half a century. Multiple mechanisms ensure that rRNA synthesis rates are appropriate for the cell's particular growth condition. Recently, important advances have been made in our understanding of rRNA transcription initiation in Escherichia coli. These include (a) a model at the atomic level of the network of protein-DNA and protein-protein interactions that recruit RNA polymerase to rRNA promoters, accounting for their extraordinary strength; (b) discovery of the nonredundant roles of two small molecule effectors, ppGpp and the initiating NTP, in regulation of rRNA transcription initiation; and (c) identification of a new component of the transcription machinery, DksA, that is absolutely required for regulation of rRNA promoter activity. Together, these advances provide clues important for our molecular understanding not only of rRNA transcription, but also of transcription in general.
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