ISSN:
1420-9071
Schlagwort(e):
Polygodial
;
warburganal
;
antifungal activity
;
Candida albicans
;
Saccharomyces cerevisiae
;
Pityrosporum ovale
;
enhancing effect
;
antioxidants
;
vitamin C
;
BHA
;
anethole
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Abstract The antifungal activity of two drimane sesquiterpene dialdehydes, polygodial (1) and warburganal (2), alone and in combination with several other substances, was examined against three fungi,Candida albicans, Saccharomyces cerevisiae andPityrosporum ovale employing a broth dilution method. Anethole significantly synergized the activity of the two sesquiterpenoids againstC. albicans andS. cerevisiae however, it had only an, additive effect againstP. ovale. By contrast, two antioxidants, ascorbic acid (vitamin C) and BHA (butylated hydroxyanisole), noticeably enhanced the activity of the sesquiterpenoids againstP. ovale, but had no, effect againstC. albicans andS. cerevisiae.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01948015
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