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  • 1
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    Electronic Resource
    Springer
    Meteorology and atmospheric physics 44 (1990), S. 167-194 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary Low-frequency modes of the monsoon are examined in the context of their radiation balance and diagnosed for the 13-month period between May 1979 and May 1980 using Earth radiation budget and cloud measurements taken by experiments carried on board the Nimbus-7 satellite. Simultaneous observations of the albedo, longwave radiation, absorbed shortwave radiation, and net radiation at the top of the atmosphere (TOA), and the total cloud fraction and cloud-top temperature are considered. The use of broad-band radiation budget measurements permits a description of the observed longwave, shortwave, and net radiative energy exchange by the low-frequency modes. When wavenumber one fields are considered, the entire morphology of the 1979 summer monsoon (pre-onset, onset, break, re-intensification, and withdrawal) can be fully explained in terms of an eastward propagating mode. Ridge passages occurred over the Arabian Sea and India in June prior to onset, during the July break, and during the retreat of the monsoon. Trough passages occurred prior to the onset during a period of increased tropical cyclone activity, at the time of the onset, and immediately following the break. These low-frequency waves can be unambiguously tracked around the world over extended time periods. The latitudinal structure of the waves indicated that a thermally direct Hadley Cell perturbation propagated eastward with the oscillation. These cells were evident from extratropical extensions of the oscillation, each about 180° of longitude out-of-phase with the tropical oscillation. Because the absorbed shortwave and emitted longwave radrative components are in phase and of nearly identical amplitudes, the net radiative effect of the low-frequency mode is small in general. However, in certain latitudinal belts, the passage of the waves induced perturbations in the net radiation. Because longwave cloud-radiative forcing acts in the same direction as latent heat release, it is able to contribute to the diabatic energetics maintaining the structure and propagation of the eastward propagating 30- to 60-day waves. Between trough and ridge, the TOA longwave flux varies in a coherent manner by on the order of 50 to 60 Wm−2.
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  • 2
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    Meteorology and atmospheric physics 44 (1990), S. 153-165 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary The interannual variability of the monthly mean upper layer thickness for the central Arabian Sea (5°N-15° N and 60° E-70° E) from a numerical model of the Indian Ocean during the period 1954–1976 is investigated in relation to Indian monsoon rainfall variability. The variability in the surface structure of the Somali Current in the western Arabian Sea is also briefly discussed. It is found that these fields show a great deal of interannual variability that is correlated with variability in Indian monsoon rainfall. Model upper layer thickness (H) is taken as a surrogate variable for thermocline depth, which is assumed to be correlated with sea surface temperature. In general, during the period 1967 to 1974, which is a period of lower than normal monsoon rainfall, the upper ocean warm water sphere is thicker (deeper thermocline which implies warmer surface water); in contrast, during the period 1954–1966, which is a period of higher than normal monsoon rainfall, the upper warm water sphere is thinner (shallower thermocline which implies cooler surface water). The filtered time series of uppper layer thickness indieates the presence of a quasi-biennial oscillation (QBO) during the wet monsoon period, but this QBO signal is conspicuously absent during the dry monsoon period. Since model H primarily responds to wind stress curl, the interannual variability of the stress curl is investigated by means of an empirical orthogonal function (EOF) analysis. The first three EOF modes represent more than 72% of the curl variance. The spatial patterns for these modes exhibit many elements of central Arabian Sea climatology. Features observed include the annual variation in the intensity of the summer monsoon ridge in the Arabian Sea and the annual zonal oscillation of the ridge during pre- and post-monsoon seasons. The time coefficients for the first EOF amplitude indicate the presence of a QBO during the wet monsoon period only, as seen in the ocean upper layer thickness. The variability in the model upper layer thickness is a passive response to variability in the wind field, or more specifically to variability in the Findlater Jet. When the winds are stronger, they drive stronger currents in the ocean and have stronger curl fields associated with them, driving stronger Ekman pumping. They transport more moisture from the southern hemisphere toward the Indian subcontinent, and they also drive a greater evaporative heat flux beneath the Findlater Jet in the Arabian Sea. It has been suggested that variability in the heat content of the Arabian Sea drives variability in Indian monsoon rainfall. The results of this study suggest that the opposite is true, that the northern Arabian Sea responds passively to variability in the monsoon system.
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  • 3
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary The role of organized tropical storms and typhoons within the West Pacific-Indian Ocean dipole of low frequency activity is examined with the aid of INSAT satellite observations. Two Asian summer monsoon seasons-1984 and 1987-are analyzed in conjunction with a satellite derived convective index. The former year was noted as an above average Indian monsoon; the latter year as an extreme Indian monsoon failure. The analysis demonstrates that the dipole region is actually an organized collection of seven smaller scale high amplitude, low frequency centers which blur together to form the semblance of a dipole which had been originally identified in 2.5° resolution outgoing Longwave Radiation (OLR) data derived from NOAA satellite measurements. The centers are basically situated over oceanic regions in the eastern and western sectors of the dipole, although, an isolated high amplitude center is also found over central Tibet. Of considerable interest is that the locations of the seven centers, whereas not equivalent, are very similar for both the 1984 and 1987 seasonsinar. The analysis indicates that there are coherent phase relationships between the eastern sector of the dipole and the western sector, but that it is not a simple dipole-like process. Rather, the four high amplitude centers, within the western sector, all fall within a longitudinal channel in which the well known, northward propagating behavior of Monsoon convection anomalies serves to modulate the east-west phase lag along the meridional channel. The result is that the western paelfic phase lags the equatorial Indian Ocean center whereas it generally phase leads the more northern centers within the Arabian Sea and Bay of Bengal. In the two years studied here, there is little evidence of east-west propagation of anomalies between he two centers. The contribution of organized tropical storms and cyclones to the amplitude and phase characteristics of the high amplitude centers is irregular but important, particularly in the eastern sector of the dipole, where up to 50% of the variance can be explained by organized storms. It is also shown that the influence of storms on the phase propagation characteristics of convective anomalies is irregular but significant.
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  • 4
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    Meteorology and atmospheric physics 44 (1990), S. 219-250 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary In this paper we have studied the low frequency variability of the sensible and latent heat flux over the Indian monsoon area. We have used an atmospheric energy budget (vertical integrated heat sources and moisture sinks), as well as the similarity theory in order to compute the surface fluxes on a darly basis. Mainly, the three following data sets were used: the First GARP Global Experiment analyzed data, the TIROS-N outgoing longwave radiation data and the Monsoon Experiment precipitation data. Our three main findings are the following. First, the variability of the temperature and the specific humidity at the surface is more important over the land than over the sea on the intraseasonal time scale (30% over land, but 20% over sea). For the wind an energy peak appears clearly around 30–40 days. The surface fluxes show an uneven variance percentage field (10% to 40%); the energy peaks stretch from 10 to 40 days. Second, the wind has a significant influence on the surface fluxes, except at some locations exclusively over the land areas. Of the temperature and the specific humidity, the temperature is the one which influences the fluxes the most. (This influence may be very strong over land.) The specific humidity may have a significant influence, over the land and sea, at the same time. Thus, one cannot neglect the influence of temperature and specific humidity over land on the intraseasonal time scale. Third, we have found a close relation between the propagation of low frequency waves and the propagation of surface flux patterns. This may suggest a feedback mechanism which relates surface processes to the northward propagation of these waves over India.
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  • 5
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    Meteorology and atmospheric physics 44 (1990), S. 265-279 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary Using a General Circulation Model developed at FSU (FSUGCM), the role of the diabatic heating on the 30–60-day oscillation is investigated. To concentrate on the radiation and the moist convection processes, an aqua planet model is employed in this paper. We have obtained a 40-day oscillation with relatively lower frequency than other GCMs without strong heating in the lower troposphere. Unlike some GCMs and simple models, the convective area does not move eastward along with the oscillation. Adiabatic cooling due to the upward motion is mostly compensated by diabatic heating. This implies that Kelvin CISK theory might not explain our 40-day oscillation. We have also examined the impact of radiative heating on the low frequency oscillation. When we reduce the radiative cooling rate, our 40-day mode does not appear and a Kelvin CISK mode appears with a faster phase speed. The impact of the different convection schemes is also investigated. With an enhanced convection scheme, zonal wave number two with a 40-day period is generated.
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  • 6
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    Meteorology and atmospheric physics 44 (1990), S. 281-292 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary The present paper discusses the build-up, the air mass transformation and the propagation of the Siberian high as well as its relations to the development of cold surges in East Asia. It has been found that (1) the genesis and development of the Siberian high result from the combined effects of the mass convergence at middle and upper-level and the radiative cooling; (2) the apparent transformation of the Siberian high over land is observed in winter, which is caused by the upward sensible heat and latent heat flux from the underlying surface; (3) the Siberian high and its attendant cold air outbreaks usually undergo a marked low-frequency, southward propagation with the period of 10–20 days; (4) activity of cold surge over the East China Sea and the South China Sea is closely related to the intensity of the Siberian high. The active cold surge occurs when the Siberian high is usually strong.
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  • 7
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    Meteorology and atmospheric physics 44 (1990), S. 251-263 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Summary The Indian summer monsoon, one of the earth's most vigorous and energetic seasonally occurring weather events, influences the global atmospheric circulation. Its onset, duration, and intensity are governed by large- and meso-scale geophysical processes, such as surface solar heating and air-sea interactions. In this paper, using innovative combinations of satellite sensor data, we investigate some of these fundamental processes which are closely tied to clouds and control the monsoon system's evolution. The study, which focuses on the monsoon period of June, 1979, examines the low-frequency variability of clouds and their effects on air-sea processes through an analysis of the complex influence clouds play on the surface heat and water budgets. First, the effects of clouds on both the solar and longwave components of the surface radiation budget are assessed using a cloud radiative forcing parameter. While the effects of clouds on the long-wave irradiance act in a manner opposite to their effects on the shortwave irradiance, only a partial compensation is found to take place and the net effect results in a maximum cloud forcing of 60 Wm−2 in the southwestern Arabian Sea. Second, employing satellite-derived precipitation and evaporation estimates, the paper analyzes the net surface fresh water budget variability around the monsoon onset. This budget is important in that fresh water affects the upper ocean density distribution and, consequently, the thermohaline circulation. Two regions are found to dominate the analysis: the western Arabian Sea, where evaporation is dominant by more than 10 mm day−1, and the eastern Arabian Sea, where precipitation is dominant by more than 10 mm day−1. Thus, a strong zonal gradient of fresh water at the surface is established during the monsoon. The last topic investigated is the intraseasonal variability of convection as analyzed using a cloud parameter indicative of deep convection. Cloud oscillations of 30–50 days, associated with the different phases of the monsoon, are found to propagate northward in the eastern Indian Ocean and eastward in the Bay of Bengal. Our analysis not only supports the hypothesis that the 30–50-day oscillation is driven by deep convection but also, and more importantly, suggests that the ocean thermal forcing is modulated by 30–50-day oscillations through cloud-induced surface radiative forcing. Although the results presented are limited in scope and preliminary because of the diffculty in quantifying the accuracy of the parameters examined, they do demonstrate: 1) the role of clouds in modulating the surface heat and water budgets, 2) the advantage of using combinations of multi-sensor and multi-platform satellite observations to quantify interrelated surface heat/water budget processes, and 3) the potential to examine the intraseasonal variability of air-sea interaction processes associated with the monsoon, even though these processes are not directly measurable from space.
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  • 8
    ISSN: 1435-604X
    Keywords: Photodynamic therapy ; Superficial bladder tumours ; Dosimetry ; Isotropic light sensors ; Photosensitizers ; Wavelength of irradiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The use of photodynamic therapy (PDT) for the treatment of superficial tumours on the bladder wall is described. Details are given on the laser, methods of delivering light into the bladder, suitable commercial dosimetry systems and instrumentation suitable for making light measurements on the bladder wall during therapy. New alternative photosensitizers are discussed in some detail. Some early clinical results are presented and the current problems with this type of therapy are highlighted.
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  • 9
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    Lasers in medical science 5 (1990), S. 43-49 
    ISSN: 1435-604X
    Keywords: Copper vapour laser ; Argon ion laser ; Port wine stains ; Telangiectasia ; Spider naevi ; Questionnaire
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract A questionnaire was sent to 242 patients who had undergone treatment with yellow light (578 nm) from a copper vapour laser for a port wine stain (PWS), for facial telangiectasia (FT), or for a spider naevus (SN). The questionnaire covered the social implications of the lesion, the physical appearance of the lesion after treatment and the patient's judgement of how the treatment has affected them. Replies were received from 73% of the patients. The replies revealed that 83% PWS, 74% FT, and 81% SN patients felt there had been an improvement in their appearance compared with 2.5% PWS, 14% FT, and 7.5% SN patients who felt that their appearance had changed for the worse. The overall impression of the treatment was also very positive, especially with PWS patients, 91% would recommend the treatment to others, 84% would have the treatment again and 60% indicated their feelings regarding their overall treatment and the effect it had on their lives was very good.
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  • 10
    ISSN: 1435-604X
    Keywords: Biliary calculi ; Laser lithotripsy ; Pulsed 504 nm dye laser ; Salivary calculi ; Urinary calculi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Biliary, urinary and salivary stones were fragmented in vitro with a flashlamp-pumped dye laser operating at 504 nm. A clinical fragmentation criterion was formulated; fragmentation was continued until all fragments had passed through a sieve with holes of 1.5×1.5 mm2. The number of shots of 50 mJ necessary for total fragmentation appeared to be proportional to the stone mass. The three types of stones showed statistically significant differences in the number of shots per unit mass, necessary for fragmentation. On biliary calculi we investigated the influence of the energy per laser pulse. For pulse energies of 32 mJ and larger, the energy necessary for fragmentation appeared to be proportional to the initial stone mass, but did not depend on the energy per pulse.
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  • 11
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    Lasers in medical science 5 (1990), S. 121-128 
    ISSN: 1435-604X
    Keywords: Hyperthermia ; Tissue optics ; Thermal properties ; Lasers ; Cancer therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The rationale of hyperthermic treatment of tumours is based on the phenomenon that several tumours have a reduced tolerance for exposure to temperatures in the region 42–47 °C for 20–30 min. Hyperthermia may also be used as an adjunct to other modalities such as chemotherapy, conventional radiation therapy or photodynamic therapy. Methods for introducing hyperthermia include electromagnetic radiation in the radiofrequency and microwave region as well as ultrasonic waves. The use of lasers emitting within the visible and near infrared part of the spectrum has the potential to initiate a local elevation of the temperature. The extension of the heated region will depend on optical wavelength, tissue composition and blood perfusion. Typical linear dimensions of the 42–47 °C temperature region will range from 2–3 mm and up to about 10 mm. Superficial tumours may be heated by direct irradiation whereas deeper lying tumours or lesions of large extent may require light delivered by one or several inserted optical fibres. Laser-induced hyperthermia may be of particular relevance in the treatment of retinal or choroidal tumours. Visible and near infrared radiation can be transmitted through the cornea, the lens and the vitreous with negligible loss. The absorption in the tumour is, however, significantly larger and the main part of the optical power will be absorbed within 0.5–5 mm into the neoplastic tissue. This paper emphasizes a discussion of the basic principles.
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  • 12
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    Lasers in medical science 5 (1990), S. 137-141 
    ISSN: 1435-604X
    Keywords: Retinal epiblastic tumours ; Uveal tumours ; Photocoagulation therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Two kinds of tumours are of particular importance in ophthalmology: the retinal epiblastic tumours, like the retinoblastoma and uveal tumours, like the uveal melanoma and the metastatic tumours. The photocoagulation therapy is sometimes used as a first treatment or as the only treatment, and this kind of therapy is useful according to our experience to complete conservative tumour therapy with radioactivity or cytostatic chemistry. A review of literature is done and we present several clinical examples from our own experience in the Lisbon Institute of ophthalmology and in the University Eye Clinic, Santa Maria Hospital, Lisbon.
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  • 13
    ISSN: 1435-604X
    Keywords: Bladder tumour ; Diagnosis ; Fluorescence ; Photodynamic therapy ; Photosensitization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Most methods of modern laser tumour therapy are physically based on the conversion of light to heat. Recently tumours have also been treated using ionizing processes for tissue ablation. Photodynamic laser therapy (PDT), however, involves light-induced non-thermal biochemical processes and the use of a photosensitizer. Several drugs are known to be stored selectively in tumours after systemic application. This transient marking can be used for diagnostic and therapeutic procedures. The marker most commonly used is dihaematoporphyrin ether/ester (DHE) intravenously injected at doses of 0.2–3.0 mg/kg bodyweight for diagnosis and therapy, respectively. The corresponding clearance intervals after injection of DHE range from 3–48 h to 25–75 h. Detection of photosensitized tumours might offer great advantages. The highly sensitive two-wavelength laser excitation method with computerized fluorescence imaging recently has been transferred to the hospital for clinical tests. Photoinduced production of singlet oxygen is claimed to be the initial process which leads to later tumour destruction and therapy. PDT has been applied to 20 patients suffering from superficial tumours (TIS GII–III) recurred after application of other treatments. The results after PDT were evaluated by three-monthly check-ups (endoscopy, cytology, bladder mapping, renal ultrasonography) as well as by computed tomography (CT) examination at 8–13 month intervals. In six patients treated by PDT no tumour recurrence has been found over the whole observation period of up to 5 years. Four patients have remained free of tumour (12 and 14 months) after repeated transurethral resection (TUR) and Nd-YAG laser therapy following PDT. Due to an initial application of insufficient irradiation four patients required a second PDT. In one patient a circumscribed dysplasia appeared at the left ostium 26 months following PDT and was treated successfully by means of thermal Nd-YAG laser irradiation following TUR. In six patients slight mucosal atypia persisted for a period of at least 2.5 years. One cystectomy had to be performed because of bladder shrinkage. The dissected bladder, however, was free of tumour. These preliminary results suggest that PDT is justified in patients who are in a worst-case situation with cystectomy recommended in case of recurrent superficial TIS bladder carcinoma and indicate the future potential of photodynamic therapy of tumours. Homogeneous irradiation of the area to be treated and a reliable light dosimetry are prerequisites for an effective tumour therapy. Standard instruments for a routine application do not exist, but are under development.
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  • 14
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    Lasers in medical science 5 (1990), S. 213-215 
    ISSN: 1435-604X
    Keywords: Gynaecological tumours ; Endometriosis ; Haematoporphyrin derivative
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
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  • 15
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    Lasers in medical science 5 (1990), S. 217-221 
    ISSN: 1435-604X
    Keywords: Oesophageal cancer ; Nd-YAG laser ; Endoscopic treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Over a 10 year period, 149 non-surgical patients were treated for palliation of an oesophageal cancer. One hundred and twenty-nine patients had an advanced cancer; 20 had a small cancer. The initial success rate was 81% and the complications rate was 3.1% for advanced cancers. Average duration of improvement after initial improvement was 138 days. Location was the only factor affecting the initial results in advanced cancers. Improvement duration was affected by the reason for treatment and an association of treatments during follow up. A complete local destruction of the small cancers was obtained in 18 patients. Three patients had a local recurrence during follow up.
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  • 16
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    Lasers in medical science 5 (1990), S. 253-269 
    ISSN: 1435-604X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Laser applications are developing rapidly in medicine. Virtually every specialty of surgery, and a number of medical specialties, are using the laser for several conditions, and the number of conditions treated seems to grow every day. This fact is of concern to policy-makers in a time of limited resources for health care. Increasingly, health policy decisions are guided by costeffectiveness studies of medical applications. This paper reviews evidence of cost-effectiveness for a number of relatively mature laser applications. In general, although available studies are suggestive of benefit, effectiveness has been demonstrated for relatively few laser applications. Little reliable cost information has been developed, although out-patient therapy and shortened length of stay in hospital seem to be demonstrated for several conditions.
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  • 17
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    Lasers in medical science 5 (1990), S. 289-292 
    ISSN: 1435-604X
    Keywords: Cancer ; Laser ; Chromophores ; Photodynamic therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Chromophores in tissue are of considerable interest for the tissue interactions with lasers in the visible light range. The natural chromophores in man are essentially melanin and red cell haemoglobin. With the development of Photodynamic Therapy (PDT) in the treatment of human cancer, the new technology of exogenous chromophores was developed and continues to expand both in laser medicine and laser surgery. This technology relates specific chromophores to specific wavelengths for the destruction of tumours and has been very effective for PDT in those instances where there is accessibility to the tumour mass by the laser beam. The problems today are concerned with how to mark these malignant foci deep in the tissue, how to detect them, and how to direct selected laser beams to the marked carcinomatous tissue. In laser medicine, the field is expanding especially for tissue and laboratory diagnostics.
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  • 18
    ISSN: 1435-604X
    Keywords: Photodynamic therapy ; PDT ; Fluorescence ; Haematoporphyrin derivative ; HPD ; Diagnosis ; Murine tumour ; Laser ; Pharmacodynamic ; Pharmacokinetic ; Regrowth delay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Eight commercially available HPD-photosensitizers intended for photodynamic therapy were tested in a murine tumour model with regard to their therapeutic efficacy. The regrowth delay of the fibrosarcoma SSK-2 on the mouse C3H, Neuherberg-line, was determined 3, 24, 48 and 72 h after injection of the drugs (dose: 9 mg kg−1 body weight). The corresponding pharmacodynamics, as measured by regrowth delay, were approximated by an exponential function and the characterizing coefficients derived. These coefficients served to quantify the photodynamic properties of the drugs. The pharmacodynamics of five substances were compared with those obtained fluorometrically. The latter showed shorter decay constants than the therapy-correlated substances which indicates different metabolic behaviour of the therapeutic and diagnostically useful fluorescent components of haematoporphyrin-derived photosensitizers.
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  • 19
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    Lasers in medical science 5 (1990), S. 337-337 
    ISSN: 1435-604X
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  • 20
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    Lasers in medical science 5 (1990), S. 381-386 
    ISSN: 1435-604X
    Keywords: HeNe laser irradiation ; Biostimulation ; Wound healing ; Capillary regeneration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Laser light of low energy is discussed to have an accelerating effect on wound healing. The aim of the present study was to proof whether HeNe laser irradiations have a positive effect on regeneration of capillaries. For this purpose aluminium chambers were implanted in the dorsal skin flap of Syrian hamsters. After coagulation of blood vessels by means of an argon laser the tissue was irradiated daily with the low energy light of a HeNe laser. Regeneration of capillaries was studied by means of intravital microscopy. The results of the study revealed a positive effect of low dose HeNe laser irradiation on the regeneration of capillaries at day 5 after the coagulation. The measurable part of the capillaries was about 27% higher for the irradiated animals compared to controls.
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  • 21
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    Lasers in medical science 5 (1990), S. 411-413 
    ISSN: 1435-604X
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  • 22
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    Polymer bulletin 23 (1990), S. 35-42 
    ISSN: 1436-2449
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary Active centers have been studied in the polymerization of propylene using highly active Mg(OEt)2/Benzoyl chloride/TiCl4 catalysts activated with AlEt3. The method for the measurement of active centers is based on the inhibiting effect of CO on polymerization. The activity of the present catalysts, which is higher than that of TiCl3 or MgCl2-supported catalyst, is mainly due to the higher concentration of active centers by one order of magnitude. In order to investigate the stability of active centers during polymerization the number of active centers are compared at various polymerization times.
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  • 23
    ISSN: 1436-2449
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary The influence of the total monomer concentration on the radical reactivity ratio r1 of butyl methacrylate (BMA) (M1)-ω-(p-vinylbenzyl ether) macromonomer of poly(2,6-dimethyl-1,4-phenylene oxide) (PPO-VBE) (M2) monomer pair was investigated. For two different molecular weights of the PPO-VBE macromonomer ( $$\bar M_n = 14,000$$ , $${{\bar M_w } \mathord{\left/ {\vphantom {{\bar M_w } {\bar M_n }}} \right. \kern-\nulldelimiterspace} {\bar M_n }} = 1.25$$ and $$\bar M_n = 5,300$$ $${{\bar M_w } \mathord{\left/ {\vphantom {{\bar M_w } {\bar M_n }}} \right. \kern-\nulldelimiterspace} {\bar M_n }} = 1.26$$ ), the determined reactivity ratio r1 decreases with the increase of the macromonomer concentration. Therefore, the reactivity of the macromonomer, 1/r1, follows the opposite trend. This dependence is due to micelles formation during copolymerization. This microsegregation process partitionates the comonomer concentrations between the bulk of solvent and around the growing chain and therefore, the experimental r1 is actually a product of the true reactivity ratio r1 0 and a partition coefficient k.
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  • 24
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    Polymer bulletin 23 (1990), S. 7-12 
    ISSN: 1436-2449
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary The 2,2 bis(4-ethynylphenyl)hexafluoropropane is prepared via an original synthesis's process using a substitution of 2,2 bis(4-triflatephenyl) hexafluoropropane by trimethylsilyl acetylene. In this process ZnO is used to remove the triflate anion formed during the reaction. This diacetylenic compound melts at 37–38°C, exhibits an onset of polymerization at 120°C. After thermal treatment at 250°C, the obtained network shows a softening point at 300°C. This network remains stable in air up to 435°C.
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    Polymer bulletin 23 (1990), S. 89-94 
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    Notes: Summary The DC conductivity of two networks — a poly(N,N-diethylacrylamide) network (N1) and a network prepared by the copolymerization of N,N-diethylacrylamide with 3 mol.% of sodium methacrylate (N2) — in deionized water in the temperature range 10–55°C was measured. While in the low-temperature range (expanded gel state) the volt-ampere (V-A) behaviour of both networks shows a semiconductive character (conductivity increases with increasing temperature), in the high-temperature range (collapsed gel state) the conductivity of the network N1 rapidly decreases with increasing temperature (metallic character). The presence of charges on the chain raises the conductivity and shifts the temperature of the change in conductivity to higher values. In the collapse region of the ionized network N2 anomalies were observed on the V-A characteristics.
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    Notes: Summary Packed column SFC has been found suitable for the rapid and detailed analysis of the isotactic and syndiotactic oligomers of MMA, when the temperature gradient technique was applied and the modifier was employed. Oligomer components from trimer to 20-mer separated completely. The heptamer fraction collected three times by SFC gave the 1H NMR spectrum of satisfactorily high S/N ratio; the spectrum agreed well with that of the standard sample. Separation by tacticity as well as by molecular weight was observed for the SFC of a mixture of the isotactic and syndiotactic oligomers. The isotactic oligomers had longer retention time than the syndiotactic oligomers of the corresponding degree of polymerization.
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    Polymer bulletin 23 (1990), S. 177-184 
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    Notes: Summary 1,4-Bis[2-(4′,4″-diheptyloxyphenyl)ethynyl]benzene and 1,4-bis[2-(3′,3″-dimethyl-4′,4″-diheptyloxyphenyl)ethynyl]benzene were synthesized by a one pot phase transfer Pd(O)/Cu(I) catalyzed three step coupling of 1,4-diiodobenzene with 2-methyl-3-butyn-2-ol and the appropriate aryl halide. Both compounds display mesomorphic behavior similar to that of the analogous 1,2-(4,4′-dialkoxyaryl)acetylenes, except that the temperature window of each phase is stabilized, such that an enantiotropic mesophase is even observed in the derivative containing a methyl branch in the mesogen. Both compounds form mesomorphic EDA complexes with p-chloranil as electron acceptor, and display a depression of the nematic-isotropic transition temperature.
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    Notes: Summary The reaction of trimethylsilyl iodide (TMSI) with 1,3-dioxolane (DXL) leads to the formation of 1-trimethylsiloxy-4-iodo-3-oxabutane. In combination with tetrabutyl ammonium triflate this compound can be used as an initiator for the polymerization of vinyl ethers. According to a living polymerization mechanism, the polymers are characterized by controlled molecular weights and narrow molecular weight distributions. The trimethylsiloxy head group originating from the initiation reaction is easily transformed into a primary hydroxyl function by hydrolysis.
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    Polymer bulletin 23 (1990), S. 525-527 
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    Notes: Abstract Some three years ago in a preliminary report from this laboratory we have proposed that the polymerization of isobutylene (IB) by the γ-tolyl-γ-valerolactone/BCl3 initiating system in CH3Cl or CH2Cl2 diluents at-30°C proceeds in a living manner by an unusual ring expansion mechanism and produces macrocyclic polyisobutylenes (PIBs) [1]. Extensive follow-up research confirmed the living nature of the polymerization, however, has failed to confirm the results of a key preliminary experiment upon which the proposition of macrocyclic polymer structure was based. Thus the results of a comparative hydrolysis/GPC experiment carried out with a relatively low molecular weight (Mn=5,400) PIB at -30°C under a blanket of N2 which gave a lower apparent molecular weight after hydrolysis than the original sample before hhydrolysis, could not be confirmed with higher molecular weight samples, i.e., with Mn=12,000, 17,000 and 30,000. As a consequence we wish to retract our earlier claim in regard to the synthesis of macrocyclic PIBs by certain lactone/BCl3 initiating systems but maintain that these polymerizations proceed in a living manner and yield asymmetric telechelic PIBs, e.g.,α-chloro-ε-carboxyl-PIBs [2].
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    Polymer bulletin 23 (1990), S. 555-562 
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    Notes: Summary The experimental results obtained by scanning tunneling microscopy (STM) studies of different carbon fibres are presented and discussed. The comparative analysis of the STM images at scales from hundreds of nanometers down to atomic scale reveals the differences of surface features for carbon fibres processed from different precursors, polyacrylonitrile fibres and pitch. The high temperature treatment of carbon fibres — the so-called graphitization process — as used to improve the stress modulus induces drastically increased ordering phenomena at the atomic level. Structural information obtained by STM on the surface of the fibres as well as in their cross sectional areas is discussed in comparison with known results of diffraction studies. STM appears to be the new powerfull technique for the detailed structural studies of surfaces of carbon fibres. The perspectives of these studies are under discussion.
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    Polymer bulletin 23 (1990), S. 295-298 
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    Notes: Summary Poly (2-vinylpyridinium dichromate) oxidizes different alcohols to their corresponding carbonyl compounds more efficiently than poly (4-vinylpyridinium dichromate). Syndiotactic form of the 2-isomer is the most efficient.
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    Notes: Summary Segmented polyether urethane (SEU) and urethaneurea (SEUU) were synthesized using ABA type triblock copolymer as a prepolymer, where A stands for poly(oxyethylene) and B stands for poly(oxytetramethylene). Lithium perchlorate was dissolved in SEU or SEUU to prepare LiC104 complexes (SEU/LiC104 and SEUU/LiC104) in film form. The highest conductivities observed here were 5.13x10-6 S cm-1 at 30°C and 3.34x10-5 S cm-1 at 50°C for LiC104/SEUU (oxyethylene-units content, 31 mol%). The ionic conductivity of these complexes was found to show the Arrhenius type temperature dependency. The effect of lithium perchlorate dissolution on the morphology of SEU and SEUU were also discussed.
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    Polymer bulletin 23 (1990), S. 353-359 
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    Notes: Summary The high-speed spinning technique has been applied to very elastic solutions of ultra-high molecular weight polyethylene in paraffin oil in an attempt to produce a strong fiber in a one-step process. At a winding speed of 4000 m/min a fiber was produced with a tensile strength of 2.3 GPa, a Young's modulus of 46 GPa and a elongation at break of 6.5%. This fiber could not be hot drawn anymore. At a winding speed of only 1 m/min the same solution yielded after spinning and hot drawing a fiber with a tensile strength of 7.2 GPa.
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    Polymer bulletin 24 (1990), S. 31-38 
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    Notes: Summary Reactions between a diepoxide and a diisocyanate can lead to copolymers having isocyanurate and oxazolidone rings in their chemical structure. Using Differential Scanning Calorimetry (DSC) and Fourier Transform Infrared Spectroscopy (FTIR), we have studied the influence of catalysts such as an imidazole or a blocked isocyanate on the polymer formation. We have identified the nature of the exotherms observed in DSC experiments with the aid of FTIR spectroscopy and observed the influence of the molar ratio of the functional groups and the amount of catalyst. We have compared the influence of these catalysts with results obtained previously with a tertiary amine.
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    Notes: Summary This paper describes a novel mechanism for the depolymerization of poly(2,6-dimethyl-1,4-phenylene oxide). This radical-anion mechanism is responsible for liquid (organic solvent)-liquid (aqueous inorganic base) phase transfer catalyzed depolymerization of poly(2,6-dimethyl-1,4-phenylene oxide). This depolymerization occurs through the addition of an aryloxy radical to the terminal phenolate anion of the polymer. The particular example discussed in this paper refers to the depolymerization of poly(2,6-dimethyl-1,4-phenylene oxide) in the presence of either 2,4,6-trimethylphenol or 4-tert-butyl-2,6-dimethylphenol. The similarities and differences between the phase transfer catalyzed polymerization of 4-bromo-2,6-dimethylphenol in the presence of 2,4,6-trimethylphenol and 4-tert-butyl-2,6-dimethylphenol and the phase transfer catalyzed depolymerization of poly(2,6-dimethyl-1,4-phenylene oxide) in the presence of the same two phenols are discussed.
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    Polymer bulletin 24 (1990), S. 93-100 
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    Notes: Summary Poly(ethylene terephthalate) PETP has been modified with a difunctional alcohol and acid in the molar relation 1:1. By dielectric relaxation measurements could be shown that the modification increases the segmental mobility (α-process). The local mobility (β-process) increases at smaller and decreases at higher concentrations of the modificators. A separation of the α-relaxation from the common relaxation process α+β could be observed with decreasing temperature.
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    Polymer bulletin 24 (1990), S. 123-128 
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    Notes: Summary The slow neutron transmission technique is used to measure the friction coefficient f of gel macromolecules moving against a solvent. It is shown that in the range of concentrations C=3–30%, f of gelatin gels is linearly dependent on C. The values of the monomer friction coefficient of gelatin and the friction coefficient at infinite dilution are determined. It is demonstrated that the friction coefficient of polyacrylamide gels varies as the viscosity of a solvent in a wide temperature range, however at temperatures below ∼25°C the deviation from proportionality is observed.
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    Polymer bulletin 24 (1990), S. 135-141 
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    Notes: Summary The polymerization of phenylacetylene induced by ultraviolet laser (266 and 355 nm) irradiation of W(CO)6 and W(CO)6-TiCl4 in CCl4 solvent was investigated. The weight-average molecular weights of the polymers reach 105. The infrared spectra indicate that the polymers have a trans-rich conjugated double bond structure. The influence of laser energy, laser wavelength and irradiation time on the polymerization was examined. Experimental data show that laser energy and wavelength are the most effective factors.
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    Polymer bulletin 23 (1990), S. 513-518 
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    Notes: Summary The characterization of polymer system by means of interaction reaction between the catalyst components of a Ziegler-Natta stereospecific system formed by TiCl3 and AlEt3 in heptane was carried out. The experimental results show that the formation and decay of the active centers are interdependent. The interaction of the catalyst components, which causes a destruction of the solid phase, influences the rate of polymerization.
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    Notes: Summary Glassy liquid crystalline poly(p-hydroxy-benzoic acid-co-ethylene terephthalate) is after rapid cooling from temperatures above Tg in a non-equilibrium state and exhibits physical ageing. It is shown that enthalpy and volume decrease with increasing annealing time. At the same undercooling, with respect to middle temperature of the major glass transition (Tgl), the rate of the equilibration process is significantly slower in the studied polymer than in an ordinary glassy amorphous polymer. The presence of a constraining ETP-rich phase exhibiting a 25 K higher glass temperature than Tgl may be the cause for this retarded enthalpy relaxation.
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    Polymer bulletin 23 (1990), S. 111-118 
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    Notes: Summary For the temperature dependence of linear crystal growth rate, the activation energy for the molecular transport could be expressed in terms of the equation of either WLF or Arrhenius. On the basis of the Arrhenius expression, the corresponding state of the crystal growth rate was formulated theoretically as $${{\ln ({G \mathord{\left/ {\vphantom {G {G_{max} }}} \right. \kern-\nulldelimiterspace} {G_{max} }})} \mathord{\left/ {\vphantom {{\ln ({G \mathord{\left/ {\vphantom {G {G_{max} }}} \right. \kern-\nulldelimiterspace} {G_{max} }})} {\ln ({{G_{max} } \mathord{\left/ {\vphantom {{G_{max} } {G_o }}} \right. \kern-\nulldelimiterspace} {G_o }})}}} \right. \kern-\nulldelimiterspace} {\ln ({{G_{max} } \mathord{\left/ {\vphantom {{G_{max} } {G_o }}} \right. \kern-\nulldelimiterspace} {G_o }})}} = {{(T_{cmax} - T)^2 } \mathord{\left/ {\vphantom {{(T_{cmax} - T)^2 } {T(T_m - T)}}} \right. \kern-\nulldelimiterspace} {T(T_m - T)}}.$$
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    Polymer bulletin 23 (1990), S. 141-148 
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    Notes: Summary Interpenetrating polymer networks (IPN's) of polyurethane and polystyrene were synthesized by simultaneous polymerization. The effect of compositional variation and the presence of a common solvent in the reaction medium on the rate of polymerization, the onset of phase separation, and the morphology of product were investigated. 1,4-Dioxane was selected as a common solvent by the swelling experiment. The rate of network formation in the early stage of polymerization process increased with increasing the polyurethane composition. When 1,4-dioxane was present in the reaction medium, the extent of reaction of both components at the onset of phase separation was higher than that of IPN's by bulk preparation. The morphology of final product was influenced by the extent of reaction at the onset of phase separation. The density, glass transition behavior, and thermal stability were also studied.
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    Polymer bulletin 23 (1990), S. 171-175 
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    Notes: Summary Copolymers of N-phenylmaleimide and ethyleneimine were synthesized in acetonitrile in the absence of initiator. The copolymers are insoluble in solvents such as DMF, CHCl3, DMSO, CH3OH, H2O. The copolymer composition as determined by elemental analyses depends on the initial monomer ratio. The thermal stability of copolymers was studied.
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    Polymer bulletin 24 (1990), S. 39-43 
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    Notes: Abstract High molecular weight poly(tert. butyl acrylate) s have been synthesized anionically using a technique derived from that of Teyssié et al. It was established that under proper conditions the sites remained living, allowing proper control of the molecular weight and yielding samples with narrow molecular weight distributions.
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    Polymer bulletin 24 (1990), S. 17-22 
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    Notes: Summary Poly (N-butyl-3,6-carbazolediyl) was synthesized by electrochemcial reduction of the NiBr2, 2,2′bipyridine/3,6 dibromo N-butylcarbazole system in N,N dimethylacetamide. The favorable interactions between solvent and butyl groups lead to the solubilization of the electroactive polymer in organic medium and allowed the determination of macromolecular and structural features by means of classical methods. From 13C NMR investigations it was concluded to a Π conjugation centered on the nitrogen atom of the carbazolic structure.
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    Notes: Abstract The initiating ability of tetramethylene zwitterions formed from cyclobutane adducts of donor olefins with TCNE was investigated. Polar solvents increased the ability of vinyl ether-TCNE cyclobutane adducts to initiate the cationic polymerization of N-vinylcarbazole. The concept of charge separation in the tetramethylene zwitterions was also investigated.
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    Notes: Summary This paper describes the phase transfer catalyzed depolymerization of poly(2,6-dimethyl-1,4-phenylene (xide) performed in the presence of either 2,4,6-trimethylphenol or 4-tert-butyl-2,6-dimethylphenol. The structure of the resulting polymers is compared to that of the corresponding polymers obtained by the phase transfer catalyzed polymerization of 4-bromo-2,6-dimethylphenol in the presence of either 2,4,6-trimethylphenol or 4-tert-butyl-2,6-dimethylphenol. Polymers obtained by depolymerization display a bimodal molecular weight distribution while those obtained by polymerization a monomodal molecular weight distribution. The polymers obtained by direct polymerization present structural units derived from some side reactions. These side reactions do not occur during the depolymerization process.
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    Notes: Summary The polyelectrolyte complex (PEC) between chitosan and carboxymethyl cellulose was studied. Turbidimetric measurements revealed that the amount of stoichiometric PEC increased gradually as the solution of one polyelectrolyte was added to the other; the turbidity of the solution reached a maximum for the stoichiometric ratio of the reacting polyelectrolytes in the mixture. At pH 4,0 the composition of the complex is very near to equimolarity. IR spectra and thermal analysis of the PEC exhibited significant differences from those of the 1:1 mixture of the starting polyelectrolytes.
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    Polymer bulletin 24 (1990), S. 151-156 
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    Notes: Abstract At 28° the spontaneous reactions of methylvinylidene cyanide (MVCN) with p-methoxystyrene, p-trimethylsiloxystyrene, styrene, isobutyl vinyl ether, ethyl vinyl ether and trimethylsilyl vinyl ether yielded alternating copolymers of potential interest as new piezoelectric materials. MVCN copolymerized with vinyl acetate in low yield using radical initiator and ZnCl2. Attempted homopolymerizations of MVCN with various initiators gave only low molecular weight oligomers, particularly trimers.
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    Polymer bulletin 24 (1990), S. 165-172 
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    Notes: Summary tert-Alkyl chlorides of the structure R-C(CH3)2Cl, where R-methyl, ethyl, tert-butyl, and neo-pentyl, were reacted with a stoichiometric quantity of acetyl sulfate at room temperature in methylene chloride diluent. Reaction conversion was monitored as a function of time using 1H NMR; structure of the sulfonated products was characterized using 1H and 13C NMR. Reactivity toward sulfonation increased with increasing size of the R group. In all cases the structure of the products was the same as would be expected from sulfonation of the olefin which results from dehydrochlorination of the tert-chloride. The observed behavior was consistent with a mechanism involving dehydrochlorination followed by addition of SO3 to yield a zwitterionic intermediate. Depending upon structure, the zwitterion may either eliminate a proton to form one or more isomeric β,γ-unsaturated sulfonic acids, or it may rearrange to form a five-membered γ-sultone. This chemistry, which is particularly useful in the synthesis of ionomers, represents a direct route to alkyl sulfonic acids when the alkyl halide is the natural starting point in the synthesis.
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    Polymer bulletin 23 (1990), S. 367-371 
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    Notes: Summary The synthesis procedure of Chen and Liu (1) was used to prepare a polyester surfactant from dimethyl 5-sulfoisophthalate, sodium salt, polyoxyethylene (MW 200) and phthalic anhydride by a two step esterification process. The surfactant has the unique structural features of multiple ionic groups and polyoxyethylene chains for hydrophilicity and aromatic ester linkages for hydrophobicity. The polyester surfactant exhibited a CMC of 0.25% (w/v) and a surface tension lowering of 23 dynes/cm. The use of the surfactant as stabilizer for the emulsion polymerization of styrene produced some unusual results. While the rate of polymerization was independent of surfactant concentration, the number of particles increased as N ∝ [S]0.91. The molecular weight of polystyrene produced was low and found not to be a function of surfactant concentration. The structural features of the surfactant suggest that a depletion stabilization mechanism might be operative in this system.
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    Polymer bulletin 23 (1990), S. 389-395 
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    Notes: Summary Poly(ethyl methacrylate-b-deuterated methyl methacrylate), poly(styrene-b-methyl methacrylate), and poly(styrene-b-dimethylsiloxane)diblock copolymers have been characterized by means of size exclusion chromatography (GPC) apparatus fitted with four detectors in series, viz continuous viscometer, UV spectrophotometer, low angle light scattering photometer, and differential refractometer. The continuous measurements of the scattered light intensity, the limiting viscosity number, the concentration, and the chemical composition permits complete determination of the molecular characteristics of block copolymers.
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    Notes: Summary Stable nitroxide radical probes are attached to styrene-divinylbenzene gel type resins through spacer arms, the length of which being 1 to 7 methylene groups. Results of electron spin resonance analysis which allows to estimate the local viscosity are discussed. Mobility of the nitroxide probes generally increases with the number of CH2 groups, the effect being compared to a decrease of cross-linking density.
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    Polymer bulletin 23 (1990), S. 447-454 
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    Notes: Summary A linear IR dichroism experiment has been devised using a FTIR instrument in combination with a photoelastic modulator. Based on the Mueller-Stokes calculus, a method to directly obtain the absorbance spectra Av parallel and Av perpendicular from the modulated interferogram is developped, which allows the sensitive evaluation of the dichroic ratio. The photoelastic modulator, in combination with a FTIR instrument, offers high sensitivity, high speed, excellent signal to noise ratio and a broad spectral range from 3300 to 850 cm-1. First experimental results obstained from SBS block copolymer are reported.
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    Notes: Summary The ability of concentrated nitric acid (65% HNO3) to initiate reactions of polymerization when in contact with acrylic and methacrylic acids and esters at room temperature in the absence of other reagents has been studied in this laboratory. In a previous paper, we presented the results when the reaction was applied to methacrylic monomers. This work reports data obtained with methyl and ethyl acrylates; high molecular weight ester-acid copolymers were produced. The nature of the products and the course of the reaction are discussed.
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    Polymer bulletin 23 (1990), S. 529-533 
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    Notes: Summary The effect of the spatial localization of a network chain by surrounding chains is incorporated into the chain probability distribution function and the network free energy is then calculated using the statistical mechanical formalism for constrained systems. In addition to a term having the classical ‘Gaussian’ form, the resulting expression contains another term which depends on both the cross-link density of the network and the plateau modulus of the uncross-linked melt.
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  • 57
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    Notes: Summary Several PMMA samples prepared in toluene with anionic initiators such as t-C4H9MgBr, n-C4H9MgCl, 1,1-diphenylhexyllithium, t-C4H9Li and t-C4H9Li(n−C4H9)3Al complex were analyzed by the on-line GPC/NMR method using a 500 MHz 1H NMR spectrometer as a real-time detector of GPC. The molecular method for a short time (≤60 min per sample) with a small amount of the sample (≈1 mg). The plots of intensities of the α-methyl proton resonances due to mm- and rr-triads against elution time showed the variation of tacticity with molecular weight of the PMMA. On the basis of the results, the natures of active species in the polymerizations were discussed.
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    Polymer bulletin 23 (1990), S. 577-581 
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    Notes: Summary The polymerization of maleic anhydride and 1,3-propylene glycol was carried out using p-toluenesulphonic acid as catalyst. The resulting material has been characterized by ir and H1nmr spectroscopy, end group analysis and gel permeation chromatography. The percentage isomerization of maleate to fumarate has been correlated with the extension of polycondensation and the steric hindrance between the condensed functional groups.
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    Polymer bulletin 23 (1990), S. 605-608 
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    Notes: Summary 129Xe NMR of xenon adsorbed in a solid EPDM rubber shows the presence of at least four distinct regions in the amorphous phase of this polymer. Changes in the relative amounts of these environments are observed upon crosslinking indicating that changes in the amorphous phase structure of the polymer have occurred.129Xe NMR provides a direct probe of the formation of a more condensed amorphous phase of the polymer matrix due to the crosslinking reaction.
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  • 60
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    Notes: Summary Three tetrathiolate (tetrathiafulvalenetetrathiolate, ethylenetetrathiolate, and butadienetetrathiolate) nickel polymers are prepared. The polymers contain mixed valence Ni ions and are ESR active based on low-spin d8 Ni (III) species. Magnetic susceptibility measurement in the range of 30–60 K suggests and antiferromagnetic interaction between the Ni ions in the polymers. Below 30K a weak ferromagnetic interaction is observed. Chemically oxidized polymers are ESR inactive, while electrical conductivity is greatly enhanced.
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    Polymer bulletin 24 (1990), S. 507-512 
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    Notes: Summary Copolymerization of tetrahydrofuran and propylene oxide catalyzed by modified H2SO4.SO3 system has been studied. Sodium perchloride was used to replace perchloric acid as co-catalyst. The copolymerization rate was obviously accelerated when using the new H2SO4.SO3−NAClO4 catalyst system. The reaction became less sensitive to the moisture.
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    Polymer bulletin 24 (1990), S. 533-538 
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    Notes: Summary A sorbent was prepared with branched polyethylenimine fixed on bead cellulose without chemical reaction. The “jack-in-the-box” effect was used by means of which a part of the originally adsorbed PEI remains, after treatment with strong acid, almost irreversibly fixed to cellulose. The sorbent contains 1.4–3.0 mmol N/g of dry matter and is able to bind some double-charged cations from acid solutions, both from buffered media (pH 2–4) and from hydrochloric acid (1–4 M).
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  • 63
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    Notes: Summary The M/G ratio, i. e., number-ratio of D-mannuronate (M) to L-gluronate (G), and diad (MM, GG, MG, etc.) and triad (MMM, MMG, MGM, etc.) frequencies were determined with 100 MHz 13C-NMR spectra for two alginate samples, M-rich and G-rich samples. The M/G ratios obtained were in accord with those determined from chemical analysis on hydrolyzed products fairly well. Molecular chain dimensions in solution were investigated by viscosity method for five alkali-metal alginates carrying Li, Na, K, Rb and Cs, and the results were discussed based on ion radius and electronegativity of alkali-metals. Finally, ion-exchange characteristics of these alginates by Ca++ ion were interpreted with M/G ratio and electronegativity.
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    Notes: Abstract Poly (ethylene oxide) (PEO) samples, obtained using diphenylzinc-water as initiator, have been used to determine some characteristics of this polymer. The unperturbed dimensions of PEO have been obtained by the application of various theoretical treatments to viscometry measurements carried out in a good solvent. The following relationship between intrinsic viscosity and weight average molecular weight has been obtained [ŋ]/dL.g•1 = 3.99x10•4M0.69 W.
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    Polymer bulletin 24 (1990), S. 607-612 
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    Notes: Summary The nitroso labeling method (1) has been used to demonstrate its possibilities for the characterization of irradiated polyethylene (LDPE) with respect to its crosslinkings and oxygen functionalities. ESR spectra of nitroso labeled LDPE consist of the superposition of the signals resulting from three different radicals. It has been shown that a relative estimation of the ketone content is possible in irradiated LDPE samples even at low concentrations thus giving a sensitive method for this functional group in polyethylene.
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    Polymer bulletin 24 (1990), S. 633-640 
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    Notes: Summary We study the formation of reversible gels induced by addition of borax in aqueous poly(vinylalcohol). Under suitable conditions, sol, gel or demixed phase is observed. We present a qualitative interpretation of the the number of inter-polymer complexes which is governed by the complexation equilibrium.
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    Polymer bulletin 24 (1990), S. 671-671 
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    Polymer bulletin 24 (1990), S. 305-308 
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    Notes: Summary A criterion (°) for testing stereoblock and heterotactic polymers is developed. The criterion takes values between 1 and-1, a value of 1 is indicative of a pure stereoblock polymer and a value of-1 indicates a pure heterotactic polymer. The criterion (°) is compared with persistence ratio (ρ) and average stereochemical sequence length. The importance of δ as an aid in the synthesis of stereoblock polymers is discussed.
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    Polymer bulletin 24 (1990), S. 333-340 
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    Notes: Summary The A-B diblock copolymers with comb shape structure were prepared from styrene (St) and either methacrylate of poly(ethyleneglycol) monomethyl ether (MPEGM) or methacrylate of poly(ethyleneglycol) (HPEGM). The surface chemical analysis of the polymer at air-solid interface by means of X-ray photoelectron spectroscopy (XPS) revealed the enrichment of MPEGM for MPEGM/St and St for HPEGM/St diblock copolymers, which indicated that the end group of the side chain determined surface composition. Dynamic contact angle measurements revealed that the migration of hydrophilic poly(ethyleneglycol) at solid-water interface occurred upon immersing the film specimen in water.
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  • 70
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    Notes: Summary The structure analysis of two conductive polymer systems-poly-4-vinylpyridine and poly(butadiene-b-4-vinylpyridine) with 7,7′,8,8′-tetracyanoquinodimethane (TCNQ)-was done by X-ray diffraction, scanning tunneling microscopy (STM) and FTIR. The charge transfer complex formed between the pyridine group and the known electron acceptor, TCNQ, is supposed to be the conductive element in these systems. In order to understand the structure of this complex, a model compound, the complex of 4-ethylpyridine (4EP) with TCNQ, 4EP/TCNQ2, was studied by the mentioned methods. It appears that there are two crystalline modifications of the model compound with different type of stacks of the TCNQ molecules. In polymer systems only one type of the complex is dominant as revealed by joint analysis of X-ray diffraction diagrams, STM and FTIR data. In the STM image of the polymer surface one can distinguish that molecular stacks with periodicities of 4.1 Å in a row are separated (12.5Å) from each other. Such organization is similiar to the one observed in conductive charge transfer complexes such as tetrathiofulvalene (TTF) with TCNQ. The ordered molecular domains are scattered on the polymer surface and take part in the formation of the conductive network.
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    Polymer bulletin 24 (1990), S. 385-389 
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    Notes: Summary Copolymers of 5-vinyl-1, 3-benzodioxole (VBD) with n-butyl acrylate and methyl methacrylate were synthesized. The copolymers were synthesized according to a designed experiment methodology and reactivity ratios were estimated using a nonlinear least squares error-in-variables procedure. The values of r1 and r2 obtained show that VBD is slightly less reactive than styrene in similar copolymerization reactions.
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    Polymer bulletin 24 (1990), S. 413-419 
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    Notes: Abstract The mesomorphic properties of 4,4′-diisocyanatoazobenzene were investigated by polarizing microscopy and DSC. It shows a nematic phase when thoroughly purified by distillation. The nematic range, however, is smaller than that of other liquid crystalline diisocyanates like 4,4′diisocyanatophenyl benzoate. A number of binary hard segment type polyurethanes was made with several diols as chain extenders and in addition ternary copolyruethanes containing two different mesogenic diisocyanates. They are crystalline materials with poor solubility. The melt temperatures of these polyurethanes are higher than those of the corresponding polymers with 4,4′-diisocyanatophenyl benzoate. Liquid crystalline behaviour could not be observed in any of the polymers probably because of the high melting transitions and relatively lower izotropization temperatures which result from the higher rigidity and symmetry of the azobenzene structure.
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    Polymer bulletin 24 (1990), S. 445-450 
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    Keywords: Poly(oxymethylene) ; Poly(ether-ether-ketone) ; DSC ; Kinetics ; Melt temperature ; Crystallization
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    Notes: Summary The influence of the melt temperature (T1) on the crystallization kinetics and the morphology of two semicrystalline polymers: poly(oxymethylene): T m 0 =198° C and poly(ether-ether-ketone) T m 0 =380° C) was investigated using thermal analysis and optical microscopy. For different melt temperatures (T1), isothermal and nonisothermal crystallizations were analysed using the AVRAMI and OZAWA models. Using different analyses, for both polymers we observed a spherulitic growth with the following influence of the melt temperature on the number of spherulites: -T1〈T m 0 produces many small spherulites -T1〉T m 0 gives rise to few large spherulites
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    Polymer bulletin 24 (1990), S. 459-466 
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    Notes: Abstract N-tert-Butylmaleimide (tBMI) polymerized readily in the presence of a radical initiator in spite of its bulky N-substituent to give a high molecular weight and less-flexible poly(substituted methylene). From kinetic investigation for the polymerization of tBMI with 2,2′-azobisisobutyronitrile (AIBN) in benzene, it was revealed that the rate of polymerization (R p) was expressed as R p=k [AIBN]0.51[tBMI]1.4, and the overall activation energy was 99.6 kJ/mol. The high polymerization of tBMI was assumed to result from the decrease in the rate of bimolecular termination between rigid polymer radicals bearing a bulky substituent. The flexibility of the polymer chain was examined by the viscometric and light scattering methods, and the effect on the polymerization reactivity was discussed.
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    Polymer bulletin 24 (1990), S. 513-519 
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    Notes: Summary Living cationic polymerization of isobutul vinyl ether (IBVE), initiated by1-iodo-1-(2-methyl propyloxy)-ethane (1) and tetraalkylammonium perchlorate yields polymers of well defined molar masses and end groups. The controlled introduction of end groups was confirmed by a model reaction and was then applied to introduce and azo initiator function. The resulting polymeric initiator was used for the synthesis of a blockcopolymer.
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    Polymer bulletin 24 (1990), S. 539-543 
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    Notes: Summary Free radical linear polymerization with instantaneous initiation was simulated on the simple cubic lattice. The monomer conversion, polydispersity index and average degree of polymerization were predicted by using the percolation model which was based on computer-simulated self-avoiding walks on the lattice. The adjusting parameters such as reactivity, termination modes, coordination number of given lattice were introduced.
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    Notes: Summary Two ethynyl end-capped ethers 2,2 Bis [ethynyl-4-phenylsulfonyl-4-phenoxy-4-phenyl] propane and 2,2 Bis [ethynyl-4-phenylcarbonyl-4-phenoxy-4-phenyl] propane have been prepared by a three steps synthesis each. They exhibit melting point followed by the thermal polymerisation of the ethynyl groups in the 200–250°C range. Curing lead to thermoset materials where Tg are respectively of 240°C and not detectable.
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  • 78
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    Keywords: Haematoporphyrin derivative ; Secondary cataract ; Phaco-Ersatz ; Endocapsular surgery ; Time-resolved fluorescence microscopy
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    Topics: Medicine , Physics , Technology
    Notes: Abstract The most common and visually significant complication of both extracapsular and endocapsular cataract extractions is the formation of a secondary cataract because of the proliferation of retained lens epithelial cells. The intraocular distribution of Photofrin II uptake after endocapsular lensectomy and lavage has been quantified to evaluate the feasibility of photodynamic therapy to prevent proliferation. Intraocular distribution was determined by measuring the fluorescence decay curves in sections of eyes using a microspectrofluorometer with high spatial and temporal resolution. An equal affinity for lens epithelium, corneal endothelium, iris and ciliary body was noted. No significant uptake in the retina was detected. Evaluation of photodynamic therapy to prevent lens epithelial proliferation will require specific localization of the drug to lens epithelium.
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    Lasers in medical science 5 (1990), S. 61-64 
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    Keywords: Vulvar intraepithelial neoplasia ; CO2 laser ; Laser evaporation
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    Topics: Medicine , Physics , Technology
    Notes: Abstract From 1982 to 1987, 18 consecutive patients with vulvar intraepithelial neoplasia were treated with CO2 laser vaporization. Prior genital tract malignancy or premalignancy was seen in 72% of the patients. The area around the commisura posterior was involved in 94% of the cases, and the disease showed multifocal localization in 56%. Of the patients 56% were disease-free after a single laser treatment; after three treatments 95% were disease-free. The mean follow up was 28 months (range 3–66); the recurrences occurred after 6–51 months, and all of them were macroscopically detectable. Colposcopy was important, whereas cytology had no importance in diagnosing the recurrences. There were no cases of progression to invasive carcinoma. The treatment was well tolerated, there were few complications and no permanent sequelae. CO2 laser vaporization of vulvar intraepithelial neoplasia represents an improvement, as long as the patients are followed up closely and informed that more than one treatment may be necessary.
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    Lasers in medical science 5 (1990), S. 71-75 
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    Keywords: Laser ; Near-infrared ; Extinction coefficient ; Scattering ; Transmission ; Tissue sample
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    Topics: Medicine , Physics , Technology
    Notes: Abstract The transmission of various tissue samples was measured between 1064 and 2000 nm. From these experiments, extinction coefficients were found to vary between 5 and 110 cm−1. In this spectral range, all the investigated tissues except fat showed two water absorption peaks centred at 1450 and 1950 nm. We have observed a greater extinction coefficient in brain than in other tissues which we have attributed to differences in scattering properties.
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    Lasers in medical science 5 (1990), S. 89-89 
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    Lasers in medical science 5 (1990), S. 115-120 
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    Keywords: Photodynamic therapy ; Photosensitization ; Pharmacokinetics ; Photofrin II ; Phthalocyanines ; Liposomes ; Lipoproteins
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    Topics: Medicine , Physics , Technology
    Notes: Abstract The scope and potential of the photodynamic therapy of tumors can be enhanced through an adequate control of the factors which improve the selectivity of tumour targeting by the systemically injected photosensitizer and increase the efficiency of photosensitized tumour damage. Promising results are obtained by using hydrophobic photosensitizers which can be specifically transported and released to the tumour by serum lipoproteins, especially low-density lipoproteins. The photosensitizer molecule should possess those structural features which induce a high probability of photoactivation by 700–800 nm light, as well as a high yield of long-lived triplet state. The use of liposome-delivered Zn-phthalocyanine as a second generation phototherapeutic agent for tumours is proposed.
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    Lasers in medical science 5 (1990), S. 171-180 
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    Notes: Abstract This article deals with the different methods used for safe laser resection. The first decision confronting the endoscopist is whether to use the flexible fibrescope under local anaesthesia or the rigid open tube under general anaesthesia. In the first section of this article we will discuss these two techniques. The second section deals with the resection technique and describes the main principles of laser resection, which are for the most part the same for both the rigid and flexible systems, but, as we explain in the second part of this section, we feel in terms of efficiency, safety and patient comfort the rigid system is by far the most appropriate instrument for laser surgery.
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    Lasers in medical science 5 (1990), S. 81-84 
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    Lasers in medical science 5 (1990), S. 87-87 
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    Lasers in medical science 5 (1990), S. 99-106 
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    Keywords: Photosensitization ; Singlet oxygen ; Porphyrins ; Phorbides ; Purpurins ; Phthalocyanines ; Naphthalocyanines
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    Topics: Medicine , Physics , Technology
    Notes: Abstract Tetrapyrroles obtain very good photophysical properties to be potent photosensitizers. They have long triplet lifetimes and high quantum yields. The singlet oxygen quantum yields are high too, because of the low energy gap between the triplet states of the most tetrapyrroles and molecular oxygen. A large variety of tetrapyrroles with different absorbance in the red and near infrared region of the spectrum and different hydrophobic properties (which are not discussed in this paper) are synthetisized and tested. A lot of them were shown to be effective sensitizers in vivo. Because of their photophysical properties, their selective accumulation and their relative biological harmfulness it could be proposed that some of these sensitizers may become important for clinical PDT.
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    Lasers in medical science 5 (1990), S. 107-113 
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    Keywords: Photodynamic therapy ; Light delivery ; Light dosimetry ; Tissue optics ; Scattering ; Absorption ; Diffusor ; Dosimetry probe
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    Topics: Medicine , Physics , Technology
    Notes: Abstract Photodynamic therapy (PDT) has attracted attention because it was considered to be a selective form of cancer treatment causing minimal damage to normal tissues. This is not exactly true, because the ratio between the photosensitizer concentrations in tumour and surrounding normal tissues is not always much more than one. Nevertheless, tumour destruction by PDT with relatively little damage to normal tissue is possible in many cases. This requires sophisticated light delivery and/or light dosimetry techniques. In this respect the limited penetration of light into biological tissues can sometimes be useful. In this paper a qualitative and sometimes quantitative discussion is given of the physical phenomena determining the energy fluence in a biological tissue. Most important is light scattering, the contribution of which depends on the geometrical conditions. Finite beam surface irradiation, irradiation of hollow organs (bladder) and interstitial irradiation are discussed separately. The emphasis is on light ‘dose’ and light dose distribution. It is emphasized that PDT dosimetry in general is complicated by photosensitizer distribution (which is usually not known), by photobleaching of the sensitizer, by possible effects of hyperthermia, and by changes in optical properties during and as a result of PDT.
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    Lasers in medical science 5 (1990), S. 185-193 
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    Keywords: Breast ; Lung ; Liver ; Rectum ; Anal tumour ablation ; Nd-YAG laser ; CO2 laser
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Conclusions More surgeons are becoming interested in laser surgery, but, in laser tumour ablation the real improvement in open surgery can only be provided by: 1. The use of the right parameters and lasers in every discipline. The recent outcome of combined CO2 and Nd-YAG delivery in the same beam (Combolaser, Lasermatic OY), and the velocity to obtain a suitable blend of the two energies, in relation with the nature of the irradiated tissues, will give to the surgeon new opportunities in laser surgery. 2. Significant results in the reduction of local recurrences, using a reproducible technique of wound sterilization by laser hyperthermia. Multicentre studies should be undertaken to answer this important question. 3. A better and earlier detection of small or microtumours with new imaging techniques, allowing for a total destruction by immunophototherapy and/or new photosensitizers, progresses in which intra-abdominal or intra-thoracic applications may found a new deal.
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  • 89
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    Lasers in medical science 5 (1990), S. 181-183 
    ISSN: 1435-604X
    Keywords: Photodynamic therapy ; Haematoporphyrin derivative ; Lung cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The main purpose of cancer therapy is to treat malignant tissue with the least damage to normal surrounding structures. Photodynamic therapy (PDT) seems to be able to fulfil this simple but fundamental premise. The mechanism of action of the photosensitizer—light system can be summarized in two main points. Chiefly, it seems to be a photodynamic process, with energy transfer from the light to the photosensitizer and from it to the oxygen molecules. Oxygen is excited and becomes singlet oxygen, which is extremely reactive and very noxious for tissues in which it develops. Secondly, a thermal mechanism related to light absorption and consequent temperature rise also seems to be involved in malignant necrosis by PDT. Thirteen males were submitted to endoscopic PDT. A total of 15 treatments were given: 2 patients were submitted to 2 sessions of PDT. Forty-eight hours after HPD administration (72 h in a few cases), the lesions were exposed to a 630 nm light from an argon-dye laser system. The total estimated energy dose delivered to the tumour surface was 90–150 J/cm2 in 11 cases. All cases treated responded well and total disappearance was obtained. Median follow-up was 9.5 months (1–20 months) and the estimated energy delivered from 90–600 J/cm2. No major complications were reported.
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  • 90
    ISSN: 1435-604X
    Keywords: Haematoporphyrin derivative ; Photodetection ; Photodynamic therapy ; ‘Early’ squamous cell carcinoma ; Pharynx ; Oesophagus ; Bronchi ; Fluoro-endoscope ; Cationic dyes ; Monoclonal antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The efficacy of photodynamic therapy (PDT) alone was evaluated on 41 ‘early’ squamous cell carcinomas of the pharynx (10), oesophagus (15) and tracheo-bronchial tree (16). All lesions but two were synchronous second primaries in ENT-patients suffering from a more extensive cancer, governing the overall oncological prognosis. Photofrin I (3 mg/kg) or Photofrin II (2 mg/kg) were injected 72 h prior to the red light irradiation, supplied by an argon pumped dye laser. A diffusing cylinder was used to obtain a homogeneous light distribution at the tumour site (60 J to 150 J/cm2). In the oesophagus and bronchi, the results are good for cancers staged in situ or microinvasive at endoscopy (two recurrencies for 23 lesions treated). For more advanced cancers (submucosal in the oesophagus or invading the bronchial cartilage), the results are less satisfactory (three recurrencies for eight lesions treated). In the pharynx where light dosimetry is more difficult, the rate of recurrencies is higher (3/10 lesions treated). In the bronchi (one case) and oesophagus (one case), the longest disease-free survival is now 5 years. The irradiation of a non-cancerous zone of normal buccal mucosa on 25 patients having received HPD showed necrosis in all cases with light doses as low as 50mW/cm2 for 20 min (60 J cm−2), even with Photofrin II. We encountered six complications (three cicatricial stenosis, two fistulae, one severe sunburn), most of them resulting from the lack of selectivity of HPD. According to these experiments, PDT is efficient at destroying early squamous cell carcinomas in the pharynx, oesophagus and bronchi, but the tumour selectivity of HPD is poor in the digestive tract lined with squamous cell epithelium. The only hope for the future lies in the synthesis of a more selective and more stable photosensitizer. This discussion reviews possible directions of research for the development of new dyes (cationic dyes, dyes attached to monoclonal antibodies, etc), for PDT and hyperthermia, for photodetection of early cancers using a fluoro-endoscope, and finally, for tumour depth profiling in hollow organs using lasers of different wavelengths.
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  • 91
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    Lasers in medical science 5 (1990), S. 241-244 
    ISSN: 1435-604X
    Keywords: CO2 laser ; Nd-YAG laser ; Endoscopic laser ; Stereotaxic laser surgery ; Intracranial tumours ; Intraorbital tumours ; Intraspinal tumours
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The early 1970s saw the birth of microscopic neurosurgery and the late 1970s the birth of laser neurosurgery. For more than 10 years now, laser radiations have been used during neurosurgical procedures: mostly for tumoral removal concerning essentially benign lesions. The reference laser has been and still is the CO2 laser, which has a limited penetration into CNS tissues. Until recently the Nd-YAG laser was used with its normal spectral transition, 1.064 μm. Because of its important diffusion in the CNS, it cannot be widely used except for shrinking large vascularized tumours such as meningiomas. The technological evolution has brought the laser specialists—physicists, medical doctors and surgeons—new concepts and new wavelengths which will progressively broaden laser applications and surgical procedures towards greater effectiveness, security and simplification. Holmium-YAG (2.1 μm), Erbium-YAG (2.9 μm) or long Nd-YAG wavelengths (1.44 or 1.32 μm) have been studied by different teams. The 1.32 μm Nd-YAG transition has been clinically used for about 2 years by a few neurosurgical teams (Beck in Munich, Roux in Paris, and more recently Lombard and Fasano in Torino, Ascher in Gratz). Laser radiations can be useful essentially during the removal of benign tumours, mostly if they are well vascularized and placed near functional structures such as the brain stem, the cranial nerves, the spinal cord: the CO2 laser is most efficient for vaporization; 1.06 Nd-YAG is effective for coagulation; 1.32 Nd-YAG provides very satisfactory photoevaporation effects if used with a superpulsed emission, and/or with a focusing handpiece, it also has good haemostatic properties with a c.w. output. The development of new optic fibre conducted wavelengths appears to be a possible answer to new requisites which should lead to the development of endoscopic neurosurgery (intraventricular tumours, discal herniations) and sterotaxic laser surgery (deep-seated intra-cerebral lesions).
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  • 92
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    Lasers in medical science 5 (1990), S. 277-280 
    ISSN: 1435-604X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract This report summarizes the results of a questionnaire which was sent to medical physicists in the United Kingdom in order to determine the extent of their involvement with lasers. Over 75% of the Health Service Areas were accounted for in the replies received. Fifty out of the 63 respondents function as Laser Protection Advisers with responsibility for advising on the control of laser hazards. Medical physicists are involved in the maintenance of approximately 40% of hospital class 4 lasers. Replies indicate assistance with the provision of new therapeutic applications but very little with respect to the use of lasers in diagnostic procedures. Medical physicists participate in other areas, such as advising on laser purchase and lecturing (29 and 26 positive replies, respectively).
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  • 93
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    Lasers in medical science 5 (1990), S. 303-308 
    ISSN: 1435-604X
    Keywords: Laser-induced autofluorescence spectra ; Cancerous ; Atherosclerotic and normal tissues ; Optical fibre
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Autofluorescence spectra in the visible range induced by an argon laser at 476 nm have been measured in vitro from cancerous, atherosclerotic and normal human and animal tissues. The main difference between diseased and normal tissues is seen as changes in the fluorescence around 540 nm and 576 nm in normal tissue. An extended investigation on fluorescence spectra of rat arteries and absorption spectra of human blood samples showed that the spectral difference of diseased tissues is due to reduction of haemoglobin concentration in cancerous and atherosclerotic tissue. The measurements performed using optical fibres showed the possibility of realizing a real-time, local spectral diagnostic for use in laser surgical procedures on atherosclerotic and cancerous lesions in vivo.
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  • 94
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    Lasers in medical science 5 (1990), S. 323-325 
    ISSN: 1435-604X
    Keywords: Nd-YAG laser ; Sapphire tips ; Stomach seromyotomy ; Chronic duodenal ulcers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract A new technique for performing a lesser-curve superficial myotomy of the stomach for the treatment of chronic duodenal ulceration has been proposed, using Nd-YAG laser energy delivered to the target via sapphire tips. A total of 12 patients have been operated on with only one haemorrhagic complication.
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  • 95
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    Lasers in medical science 5 (1990), S. 331-332 
    ISSN: 1435-604X
    Source: Springer Online Journal Archives 1860-2000
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  • 96
    ISSN: 1435-604X
    Keywords: Haematoporphyrin derivative ; Singlet oxygen ; Photodynamic therapy ; Dosimetry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Description / Table of Contents: Résumé La photochimiothérapie est un nouveau traitement des cancers débutants. Alors que des essais cliniques de phase 1–2 sont entrepris, les indications pour ce type de traitement demeurent rares, principalement du fait d'une dosimétrie approximative de la captation de l'hématoporphyrine dérivée par les tissus cancéreux humains. La fluorescence émise par l'HPD peut Être utilisée in-vivo pour un diagnostique ‘topographique’ de la répartition de l'HPD, mais aussi le dosage quantitatif des espèces fluorescentes présentes dans le mélange HPD. Le dosage de l'oxygène singulet, généré lors de la réaction photochimique, est nettement plus difficile à réaliser mais a été proposé pour le dosage in-vivo des formes porphyriniques ‘actives’ présentes dans le milieu. Les applications cliniques de telles mesures représentent une condition essentielle pour le developpement de la photochimiothérapie car à côté des possibilités de diagnotiques offertes par l'analyse de la répartition intratumorale de l'HPD, un dosage précis permettrait d'optimiser le moment du traitement, arbitrairement fixé aujourd'hui à 72 heures.
    Notes: Abstract Photodynamic therapy is a new treatment for early carcinomas. Although undergoing phase 1/2 clinical assays, clinical indications for this therapy remain rare mainly because of the approximate dosimetry of HPD uptake by tumour tissues in human beings. In this review we present the potential interest and limits of both direct fluorescence detection or dosimetry of HPD and in vivo measurements of singlet oxygen, produced during photodynamic therapy. Clinical applications of such measurements should represent one of the main conditions for the future development of photodynamic therapy.
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  • 97
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    Lasers in medical science 5 (1990), S. 281-287 
    ISSN: 1435-604X
    Keywords: Laser ; Anastomosis ; Aneurysm ; Microsurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Laser assisted microvascular anastomosis (LAMA) was performed on rat femoral arteries anddd veins using a milliwatt CO2 laser. The histological appearance of the anastomoses was assessed immediately after the procedure and at regular intervals up to seven months. There was extensive thermal-induced transmural necrosis. The weld at the anastomosis was shown to comprise of fibrin, which later organized into fibrous tissue. Re-endothelialization occurred earlier in veins, and the endothelial nature of the surface cells was confirmed by factor VIII-related antigen positivity by the avidin-biotin peroxidase complex technique. Healing was complete by 9 weeks, but the vessel was not reconstituted to its normal appearance. At the site of the anastomosis 20% of the vessels had false aneurysms.
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  • 98
    ISSN: 1435-1528
    Keywords: Doi-Edwards theory ; reptation ; viscoelastic behavior ; polybutadiene ; molecular weight distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Abstract Linear viscoelastic behavior of narrow molecular weight distribution 1,4 polybutadiene samples $$(\bar M_w /\bar M_n \sim 1.2)$$ with molecular weights between 42500 and 779000 has been correlated with molecular structure using a simple modification of the Doi-Edwards theory of reptation. The entire GPC curve is required for the calculations of viscoelastic behavior. The plateau modulus obtained from the experimental data is comparable to literature values, while the equilibrium compliance (which is indicative of polydispersity) is greater than values reported in the literature for nearly monodisperse polybutadienes. Reasonable agreement between theory and experiment is obtained over the entire molecular weight range. The agreement between theory and experiment using the GPC curve is better than that obtained by assuming the polymer to be monodisperse or by using the Doi fluctuation model. The model appears to break down for a more polydisperse sample $$(\bar M_w /\bar M_n = 1.7)$$ . This study indicates that it may be possible to use the Doi-Edwards theory to explain the viscoelastic behavior of narrow MWD polybutadienes without introducing any new concepts into the theory (fluctuations, constraints release, etc.).
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  • 99
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    Rheologica acta 29 (1990), S. 174-174 
    ISSN: 1435-1528
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
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  • 100
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    Rheologica acta 29 (1990), S. 163-169 
    ISSN: 1435-1528
    Keywords: Bingham ; yieldstress ; differentialviscosity ; falling-ball experiments
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Abstract An experiment is described to determine the two Bingham material constants (yield stressτ f and differential viscosity $$\hat \eta $$ ) of viscoplastic fluids. The principle of the experiment is based on the falling-ball technique, where the stationary velocities of balls with different diameters and densities are measured. The required theory to calculate the Bingham material constants is illustrated. Experimental results of aqueous Carbopol 941-solutions are reported. These are listed in dependence of concentration in tables and diagrams.
    Notes: Zusammenfassung Es wird ein Versuchsaufbau beschrieben, der es ermöglicht, die beiden Binghamschen Stoffparameter (Fließspannungτ f und differentielle Viskosität $$\hat \eta $$ ) einer viskoplastischen Flüssigkeit zu bestimmen. Der Versuch basiert auf dem Kugelfallprinzip, bei dem in einem Zylinder die stationäre Sinkgeschwindigkeit von Kugeln im Schwerefeld gemessen werden. Neben der Geschwindigkeit gehen das spezifische Gewicht der Flüssigkeit sowie die Geometrie und das spezifische Gewicht verschieden großer Kugeln in die Berechnung der Stoffparameter ein. Die zugehörige Theorie wird kurz erläutert. Im experimentellen Teil werden wäßrige Carbopol 941-Lösungen untersucht. Die Ergebnisse sind in Abhängigkeit der Konzentration tabellarisch angegeben und graphisch dargestellt.
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