Publikationsdatum:
1982-12-24
Beschreibung:
Monoclonal antibodies subcutaneously injected into mice track to regional lymph nodes and specifically label target cells there. The lymphatic route of administration can be expected to provide much higher sensitivity, higher target-to-background ratio, faster localization, and lower toxicity than the intravenous route when the aim is to diagnose or treat tumor metastases or lymphoma in the lymph nodes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Weinstein, J N -- Parker, R J -- Keenan, A M -- Dower, S K -- Morse, H C 3rd -- Sieber, S M -- New York, N.Y. -- Science. 1982 Dec 24;218(4579):1334-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7146917" target="_blank"〉PubMed〈/a〉
Schlagwort(e):
Animals
;
*Antibodies, Monoclonal/administration & dosage
;
Injections, Subcutaneous
;
Lymph Nodes/*cytology
;
Major Histocompatibility Complex
;
Methods
;
Mice
;
Mice, Inbred C57BL
;
Neoplasm Metastasis/*diagnosis
Print ISSN:
0036-8075
Digitale ISSN:
1095-9203
Thema:
Biologie
,
Chemie und Pharmazie
,
Informatik
,
Medizin
,
Allgemeine Naturwissenschaft
,
Physik
Permalink