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  • Artikel  (2.643)
  • American Association for the Advancement of Science (AAAS)  (1.930)
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  • 1
    Digitale Medien
    Digitale Medien
    A WEAK HUMAN MLR LOCUS MAPPING AT THE RIGHT OF A CROSSING-OVER BETWEEN HLA-D, Bf AND GLO (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: An unexpected MLR reaction has been observed between three HLA-identical sibs; it consists of a bidirectional positive MLR between identical female twins and a sister. No argument for a lymphoid mosaic could be found, although twins were frequent in the family; similary no HLA-A/B or HLA-B/D recombinant could be demonstrated.The MLR, although weak, was highly reproducible. PLTs could be raised between the sibs, without an apparent segregation in this family nor in five other families, but such PLTs discriminated well between the positive and negative controls. In the absence of any proof that such a weak MLR locus could be on another chromosome than chromosome 6, two lines of argument are indirect evidences that such a locus could be indeed on chromosome 6: one of the sibs differs from the two others for two markers outside HLA-D-DR-Bf: glyoxalate (GLO) and red blood group P.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00667.x
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  • 2
    Digitale Medien
    Digitale Medien
    Persistent infections in salmonid fish cells with infectious pancreatic necrosis virus (IPNV) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Two cell lines that are persistently infected with IPN virus have been established. Viral persistence in the cultures was demonstrated by the detection of infectious virus (102-105,5 TCID/ml50) in the culture fluids, by specific immunofluorescence, and by their resistance to superinfection by homologous virus. The growth, rate of these cells was indistinguishable from normal, uninfected cells. Virus stocks harvested from persistently infected cultures contained a greater proportion of defective, interfering particles than those from lytically infected cells which suggests that these particles may be responsible for the maintenance of these carrier cultures.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00034.x
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  • 3
    Digitale Medien
    Digitale Medien
    Electron microscopy of an ulcerative dermal necrosis (UDN)-like salmon disease in Finland (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. An ulcerative dermal necrosis-like salmon disease appeared in Laukaa Central Fish Culture Station in Middle-Finland in autumn 1976 showing lesions in different sites on diseased landlocked salmon Salmo salar L., sea trout Salmo trutta trutta L. and brown trout Salmo trutta lacustris L. Lesions from the diseased landlocked salmon were studied by transmission and scanning electron microscopy.Both aquatic bacteria and fungi grew in abundance in the lesions, changing the fine structure of the epidermis.In all of the lesions studied virus-like particles 30–33 nm in diameter were found. The relationship of these particles to the disease is still unresolved.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00041.x
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  • 4
    Digitale Medien
    Digitale Medien
    Changes in the spleen of the channel catfish Ictalurus punetatus Rafinesque indueed by infection with Aeromonas hydrophila (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. A virulent, 2,3-butanediol positive culture of Aeromonas hydrophila, subspecies hydrophila, was fed or injected intraperitoneally into channel catfish. The positive infection and tissue involvement were monitored by the 2,3-butanediol test with tissue homogenate enriched with a buffered nutrient broth containing dextrose. The results revealed that the fish infected orally showed very little or no spleen involvement. Fish infected intraperitoneally, however, showed spleen involvement in a very short time, accompanied by the rapid onset of an acute systemic infection.Light and electron microscope studies of the spleen revealed that the pathogenic bacteria were mainly located within the reticular sheath of the ellipsoids and only sparsely in the surrounding regions, and that intense phagocytic activity of macro-phages had taken place in the ellipsoids. It was also observed that the phagocytized bacteria divide extracellularly, and probably intracellularly, resulting in the destruction of the endothelial and reticular cells of the ellipsoids. This finding substantiates the cytolytic and fibrolytic capacities of A. hydrophila for destroying host defence systems and may contribute to its invasive powers. Other cytological changes in cells in spleen after infection are described, and the resistance of A. hydrophila to intracellular enzymatic digestion by the macrophages is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00023.x
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  • 5
    Digitale Medien
    Digitale Medien
    Bacterial meningitis in farmed rainbow trout Salmo gairdneri Richardson affected with chronic pancreatic necrosis (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Chronic mortalities associated with meningeal and pancreatic lesions are described, from two trout farms in Scotland. Histopathological and microbiological studies suggested that bacterial infection with strains of Pseudomonas fluorescens of low pathogenicity was developing in fish already affected by the lesions of chronic infectious pancreatic necrosis virus infection (IPN). Antibiotic therapy reduced losses temporarily; eradication of the virus resulted in complete elimination of the condition.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00016.x
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  • 6
    Digitale Medien
    Digitale Medien
    Effect of host spawning on Echinorhynchus salmonis Müller, 1784 (Acanthocephala: Echinorhynchidae) maturation and localization (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00021.x
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  • 7
    Digitale Medien
    Digitale Medien
    Host-specific pathogenicity of strains of Vibrio anguillarum isolated from rainbow trout Salmo gairdneri Richardson and saithe Pollachius virens (L.) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Vibrio anguillarum strains isolated from diseased rainbow trout were found to be pathogenic to salmonids and probably to a very low extent to saithe. Strains isolated from saithe were pathogenic to saithe and non-pathogenic to salmonids.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00004.x
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  • 8
    Digitale Medien
    Digitale Medien
    Studies on Herpesvirus scophthalmi infection of turbot Scophthalmus maximus (L.) ultrastructural observations (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Recent heavy mortalities amongst O+ group turbot at a fish farm were found to be associated with a herpes-type viral infection of the epithelia of the skin and gills. The morphology of the virus is described with ultrastructural observations on its morphogenesis and release from infected cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00033.x
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  • 9
    Digitale Medien
    Digitale Medien
    Proliferative kidney disease in rainbow trout Salmo gairdneri Richardson (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Two entirely separate outbreaks of PKD are described in an attempt to properly define the condition and enable it to be differentiated from other diseases of a similar nature. Losses of up to 75% of fingerling rainbow trout were recorded in one outbreak, illustrating the potentially serious nature of the disease. Although the kidneys showed the most obvious pathological changes, other organs were also affected. The host response was granulomatous in type, the foci of each cellular reaction being 5-20 μm eosinophilic cells considered to be parasitic. The cytoplasm of these cells contained numerous electron dense bodies some with a tail, but each with an electron lucent bar always orientated at right angles to the plasmalemma whenever they were near it. The most obvious cytoplasmic inclusion of these ‘parasites’ were other cells numbering up to five or six, each with its own nucleus and nucleolus, but devoid of any of the small electron dense bodies. The significance of either of these inclusions is unknown.A limited differential diagnosis is given, and the argument presented that the condition PKD is the result of infection by a parasite, possibly an amoeba, in combination with poor quality water.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00008.x
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  • 10
    Digitale Medien
    Digitale Medien
    The effect of temperature on agglutination activity of coho salmon Oncorhynchus kisutch (Walbaum) antiserum (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. The effects of temperature on the activity of antisera from coho salmon (oncorhynchus kisutch) and from rabbit were compared. Agglutination activity of salmon anti-Aeromonas salmonicida serum declined following incubation at 55°C whereas rabbit antiserum lost agglutination activity after incubation at 65°C.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00011.x
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  • 11
    Digitale Medien
    Digitale Medien
    Infectious pancreatic necrosis virus of salmonids: biological and antigenic features of a pathogenic strain and of a non-pathogenic variant selected in RTG-2 cells (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. A non-pathogenic cell culture adapted variant was obtained from a normally pathogenic strain of IPN virus (Sp type) after several passages in RTG-2 cells. This cell culture modified (CCA) strain was compared with the original wild (W) strain in various tests. Cross neutralization tests showed no obvious antigenic difference between the two. However the CCA strain was neutralized by a 1:5000 dilution of normal trout serum whereas the W strain was not. In RTG-2 cells, CCA strain gave both large and small plaques, whereas the W strain gave only small ones. Both virus strains were heat sensitive and labile to cyclic freezing and thawing. The CCA virus was more stable in storage at 4°C under different pH conditions and its growth in RTG-2 cells was more rapid. The rt (supraoptimal temperature at which viral yield is depressed by 90%) appeared to be 19-20°C for the CCA strain and 18-19°C for the W strain. Pre-treatment of RTG-2 cells with ultraviolet inactivated CCA virus could inhibit growth of W virus, but had no effect on replication of homologous virus.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00035.x
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  • 12
    Digitale Medien
    Digitale Medien
    Book reviews (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Book reviewed in this articles: Textbook of Fish Diseases for Veterinarians and Biologists, 3rd edn. By Erwin Amlacher. Marine Ecology and Fisheries. By D.H. Cushing Eel Capture, Culture, Processing and Marketing. By David M. Forrest. Eel Capture, Culture, Processing and Marketing. By David M. Forrest.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00013.x
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  • 13
    Digitale Medien
    Digitale Medien
    Studies on Herpesvirus scophthalmi infection of turbot Scophthalmus maximus (L.): Histopathological observations (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. The histological features of the disease caused by infection of turbot by Herpesvirus scophthalmi are described. Infection of epidermal cells of skin and gill resulted in the formation of giant cells showing a variety of nuclear and cytoplasmic changes associated with the replication of the virus. The effects of the condition together with possible control measures are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00027.x
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  • 14
    Digitale Medien
    Digitale Medien
    Febrile responses of goldfish Carassius auratus (L.)to Aeromonas hydrophila and to Escherichia coli endotoxin (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00031.x
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  • 15
    Digitale Medien
    Digitale Medien
    Frequency and distribution patterns of Saprolegnia infection in wild and hatchery-reared brown trout Salmo trutta L. and char Salvelinus alpinus (L.) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Fungal infection of sexually mature brown trout and char was associated with a particular type of Saprolegnia exhibiting a low degree of homothallic sexuality. Hatchery-reared brown trout were more severely infected (in terms of the % area of the body covered with the fungus) than were wild fish. The fins of hatchery-reared fish were particularly prone to Saprolegnia infection regardless of sex. In wild brown trout, a sexual difference in the pattern of infection was demonstrated. The flanks of the male fish appeared to be more prone to infection when compared with the female and there was a greater susceptibility of the caudal and ventral fin of the female when compared with the male. Evidence is presented which suggests that the incidence of infection in mature male salmonid fish prior to spawning is significantly greater than in the females. This difference may not be apparent in spent fish after spawning. These findings are discussed in relation to the background concentration of fungal spores in the water, the behavioural characteristics of spawning fish and differences in epidermal structure.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00006.x
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  • 16
    Digitale Medien
    Digitale Medien
    Nifurpirinol (Furanace; P-7138) related lesions on channel catfish Ictalurus punctatus (Rafinesque) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Skin lesions developed on channel catfish, Ictalurus punctatus, exposed to 0-5 mg/1 Furanace for 4 or 14 days. Lesions developed 3 days after the 4-day exposure and on the eleventh day of the 14-day exposure. The lesions continued to develop after the fish were moved to untreated water. The lesions which began as dull areas of skin, sometimes resulted in erosion of skin and muscle which exposed the vertebrae. Bacteria were not isolated from the lesions except those with severely eroded muscle. The gills possessed lesions characteristic of a response to a toxic chemical agent.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00010.x
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  • 17
    Digitale Medien
    Digitale Medien
    Exophiala salmonis infection in Atlantic salmon Salmo salar L. (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Infection of Atlantic salmon, Salmo salar L., in seawater with Exophiala salmonis is described. Histological effects consisted principally of granuloma formation, especially in the posterior kidney and spread appeared to occur both by extension and by the liaematogenous route. The nature of the outbreak suggested that the original infection occurred via contaminated food.A comparison is made between this condition and systemic mycoses in other species.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00040.x
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  • 18
    Digitale Medien
    Digitale Medien
    Book Reviews (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Book reviewed in this articles: Microbiological Methods, 4th edn. By C. H. Collins and P. M. Lyne. Ecological Aspects of Parasitology. Edited by C.R. Kennedy. Developments in Aquaculture and Fisheries Science, Volume I. Farming Marine Organisms low in the Food chain. By P. Korringa. Ikhtiopatologiya (Ichthyopathology). By O.N. Bauer, V.A. Musselius, V.M. Nikolaeva and Yu. A. Strelkov. Methods for the Diagnosis of Fish Diseases. By Z. Lucky.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00044.x
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  • 19
    Digitale Medien
    Digitale Medien
    Uptake and multiplication of spring viraemia of carp virus in carp, Cyprinus carpio L. (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00029.x
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  • 20
    Digitale Medien
    Digitale Medien
    Book Reviews (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Book reviewed in this articles: Animal Microbiology, Volume 1. By A. Buxton and G. R. Fraser. Disease of Marine Aquarium Fishes. By Mark P. Dulin All about Marine Aquarium Fish Diseases. By C. Heinz-Hehmann Reichenbach-Klinke. The Eel. By F. W. Tesch. Textbook of Fish Culture, Breeding and Cultivation of Fish., 2nd edn. By M. Huet. Parasite Invasion. Symposia of the British Society for Parasitology, Volume 15. Edited by Angela E. R. Taylor and R. Muller. Fluorescent Protein Tracing, 4th edition. Edited by R. Q. Nairn. Organization of Nematodes. Edited by N. A. Croll. Biochemistry of Parasitic Protozoa. By W. E. Gutteeidge and G. H. Coombs. Marine Helminths and Human Health. By H. H. Williams and Ablene Jones. Anthelmintic Control of Parasites in Fish. Helminths in Fish in Bulgaria, Hungary, Rumania and Yugoslavia. Technical Hematology, 2nd edn. By A. Simmons
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00032.x
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  • 21
    Digitale Medien
    Digitale Medien
    Algal infections of fish tissue: a recent record and review (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Algal infections on five carp are described and related to the known literature concerning algal-fish associations.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00018.x
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  • 22
    Digitale Medien
    Digitale Medien
    Infection by an Ichthyophonus–like fungus in the deep-sea scabbard fish Aphanopus carbo (LOWQ) (Trichiuridae) in the North East Atlantic (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00020.x
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  • 23
    Digitale Medien
    Digitale Medien
    Haemogregavina sachai n.sp. from cultured turbot Scophthabnus maximus (L.) in Scotland (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. A new species of pathogenic haemogregarine is described from farmed turbot (Scophthalmus maximus L.) as Hamogregarina sachai and its life cycle is demonstrated in its final host. An intralexicocytic schizogony followed by an intraerythrocytic schizogony was observed. This appears to be only the second time that a complete life cycle in the vertebrate host has been described for a marine fish haemogregarine.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00037.x
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  • 24
    Digitale Medien
    Digitale Medien
    Fine structure of the peritrichous ectocommensal Zoothamnium sp. with emphasis on its mode of attachment to penaeid shrimp (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. The colonial peritrich Zoottiamnium sp. is a common ectocommensal of shrimp. Heavy branchial infestations of this protozoan can cause mass mortalities of commercially important penaeid species in shrimp culture. In an effort to better understand the morphology of these organisms, the ciliates and their attachment to gills and pereiopods of Penaeus aztecus and P. setiferus were examined by transmission and scanning electron microscopy. Each zooid contains peristomial rows of cilia, numerous food vacuoles, a large macronucleus, one or more contractile vacuoles, freeribosomes, abundant mitochondria, and rough endoplasmic reticulum. The contractile spasmonehie is surrounded by striated tubules that appear to develop from scopular cilia. The pellicular surface is crenated and has numerous pores. The base of the ciliate's stalk forms a circular disc that fuses with the epicuticle but does not penetrate the underlying cuticle or epithelium. Intertwining microfibrils and osmiophilic particles in the stalk accumulate along the base and merge with the cuticular surface coat. This mode of attachment inflicts no damage to the host tissue and elicits no appreciable pathological response. The shrimp apparently suffocate when dense colonies reduce the respiratory surface area.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00036.x
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  • 25
    Digitale Medien
    Digitale Medien
    A new myxosporidan, Dicauda atherinodi n.g., n. sp. of the minnow, Notropis atherinoides Rafinesque (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Dicauda atherinoidi n.g., n. sp. (Protozoa: Myxosporida) was found in feral minnows, Notropis atherinoides (Cyprinidae), from western Lake Erie (Sterling State Park), Michigan, and the lower Mohawk and Hudson Rivers, New York. Dicauda, closely related to Myxobolus, differs from it in having two, occasionally three or more, rigid tail-like possibly mucoid appendages attached to the sutural ridge. The cysts are subdermal and most abundant on the head. Histological damage is not striking.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00038.x
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  • 26
    Digitale Medien
    Digitale Medien
    Costiasis of Atlantic salmon, Salmo salar L. smelts in seawater (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00043.x
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  • 27
    Digitale Medien
    Digitale Medien
    Humoral antibody production by New Zealand eels, against the intestinal trematode Telogaster opisthorchis Macfarlane, 1945 (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. It was shown by agar-gel diffusion and passive haemagglutination that serum from the New Zealand eel Anguilla australis schmidtii Phillips and gut mucus from Anguilla dieffenbachii Gray contained precipitating antibody against antigen prepared from the intestinal trematode Telogaster opisthorchis MacFarlane, 1945. The estimated molecular weight determined by gel-filtration on Sephadex G-200 was 670,000 daltons. The 2-mercaptoethanol sensitivity of this antibody suggested it was a macroglobulin analagous to γ M.Eel sera also contained naturally occurring agglutinins and lysins against sheep RBC's. Agglutinins had an approximate molecular weight of 142,000, were sensitive to 2-mercaptoethanol and occurred more frequently among larger eels. It was suggested that the appearance of agglutinins was an immunological phenomenon and that these antibodies were directed against the ABO system.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00042.x
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  • 28
    Digitale Medien
    Digitale Medien
    Studies on the epizootiology of Myxobolus insidiosus Wyatt and Pratt, 1963 (Protozoa: Myxosporida) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Myxobolus insidiosus from the striated musculature of chinook salmon, Oncorhynchus tshawytscha (Walbaum), was studied in disease free and naturally contaminated waters. Infection could not be induced in susceptible fish in a disease free water supply by any means triad. Experiments in naturally contaminated waters provided data on minimum and other exposure times. Studies were also carried out on the effect of water temperature, different substrates and flow rates, time of year and size of fish on infection. The rainbow trout, Salmo gairdneri Richardson, was also checked for infection and not found with this disease in naturally contaminated waters. Transovarian infection was ruled out.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00025.x
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  • 29
    Digitale Medien
    Digitale Medien
    The frequency distribution of tetracotyles of Apatemon gracilis pellucidus (Yamaguti, 1933) in stickleback Culaea inconstans (Kirtland) populations of homogeneous age and size structure (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. The frequency distribution of tetracotyles of Apatemon gracilis pellucidus in natural populations of brook sticklebacks Culaea inconstans homogeneous for age and size were fitted to negative binomial curves. Values of k were unusually high while the degree of overdispersion was correspondingly low. It is suggested that these properties of the distributions are a function of the homogeneity of the host population.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00028.x
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  • 30
    Digitale Medien
    Digitale Medien
    Ecological observations on the commercial sand crab, Portunus pelagicus (L.), and its parasite, Sacculina granifera Boschma, 1973 (Cirripedia: Rhizocephala) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Sacculina granifera was found in 12% of commercial sandcrabs, Portunus pelagicus, in Moreton Bay irrespective of sex. Although male and female crabs were randomly distributed about Moreton Bay, egg bearing females were most common at the seaward station. This and the distribution of epizoic barnacles on gills and carapace suggest the sexes school separately. The increased prevalence of barnacles on the carapace of infected crabs indicates Sacculina inhibits moulting. The distribution of interna infections in small crabs towards south and west and externa infections in large crabs in the easterly, seaward stations suggests Sacculina preferentially attacks young crabs as they move inshore and then induces crabs to behave like ‘berried’ (i.e. egg bearing) females by moving seaward as they grow. Morphologically female crabs are little changed by Sacculina, but the males show considerable modification which is reflected most accurately in the shortening of the chelar propodus to proportions similar to normal females. Infected crabs are sterile and internally the hepatopancreas becomes green rather than tan. Parasitized crabs were seen to groom their externae as ‘berried’ females groom their egg masses.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00014.x
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  • 31
    Digitale Medien
    Digitale Medien
    Foreword (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00001.x
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  • 32
    Digitale Medien
    Digitale Medien
    BOOK REVIEWS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Book reviewed in this articles: Introduction to Medical Laboratory Technology. By F. J. Baker and R. E. Silverton. The Dermatology of Fishes, a Bibliography. By J. P. Hatton, R.J. Roberts and A. M. Bullock. Principles of Pathobiology. By M. F. La Via and R. B. Hill. Haematology—Principles and Procedures. By B. A. Brown. Fish and River Pollution. By J. R. Erichsen Jones. Diseases of Fish. By C. van Duijn.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00022.x
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  • 33
    Digitale Medien
    Digitale Medien
    Saprolegnias of salmonid fish in Windermere: a critical analysis (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Fungal cultures attributed to the Saprolegnia parasitica-diclina complex isolated from diseased salmonids, diseased coarse fish and natural water samples, are compared critically. The two species concept is not sustained and only S. diclina Humphrey is conserved. This results in a more flexible framework for comparing isolates within this species and three groups are distinguished here, based on growth characteristics and length/breadth (L/B) ratio of the oogonium. Oospore size is also considered in this connection. In Windermere (English Lake District) only Saprolegnia diclina Type 1 (L/B ratio ≥2≥13%) occurs as a parasite on salmonid fish. Only S. diclina Type 2 (L/B ratio ≥2 ≤12%) occurs as a parasite on perch Perca fluviatilis L. Saprolegnia diclina Type 3 (L/B ratio ≥2≤10%) is purely saprophytic. An attempt is made to fit S. parasitica-diclina isolates from natural water samples into this scheme so that the potential infectivity for a particular kind of fish could be assessed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00005.x
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  • 34
    Digitale Medien
    Digitale Medien
    Studies on the pathogenesis of streptococcal infection in cultured yellowtails Seriola spp.: the fate of Streptococcus sp. bacteria after inoculation (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. The causative agent of streptococcal infection of yellowtails has been isolated but no information is presently available with respect to the mechanism of infection. The present study deals with the growth of the bacteria in the fish body at various periods after either per-oral or per-cutaneous challenge with Streptococcus sp. YT-3 strain at different passage levels. After percutaneous challenge with bacteria of high virulence, the kidneys retained the bacteria with the relatively high count of 107 cells per gram of tissue while in other organs, although high concentrations of 105-106 cells were detected in 10 min, this was followed by a progressive decrease up to 24 h post-inoculation with a subsequent rapid increase during the later stages of the disease process. The highest rate of growth was obtained in the intestine, where 107 cells were detected at 72 h after inoculation. After oral challenge, the bacteria were detected at high levels from organs and blood within 10 min but they were completely removed from all organs except the intestine within 24 h.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00009.x
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  • 35
    Digitale Medien
    Digitale Medien
    On differences in skin tumours of Pacific and Atlantic Flatfish (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Pacific flatfish from North American and Japanese coastal waters regularly manifest skin tumours. Those are generally papillomas, which develop from primary inflammatory nodules (vascularized nodules) on fish of a few months's age. Inside the epidermal part of the tumour slightly dedifferentiated malpighian cells change to rounded enlarged cells showing evidence of considerable degeneration (vacuolization and destruction of the cell organelles). These ‘X-cells’, which compose the major part of the mature tumour, always remain characteristically separated from the surface, from the basal lamina, and from each other, by non-enlarged ‘enyelope cells’.Oval, similarly degenerate cells also occur in the tumour stroma, especially in the nodule-like pre-papillomatous stages and here they originate apparently from fibroblasts.In the Atlantic, on the other hand, skin papillomas and other neoplastic skin growths occur relatively infrequently. The skin papillomas of Atlantic flatfish are considerably less complex. They belong to the relatively simple type which predominates in fishes in general–hyperplastic epidermal papillae which are supported and natured by branched folds of the dermal tissue (stroma).Considering the close relationship between the Pacific and Atlantic flatfishes, the distinctive structure of the skin tumours of Pacific fish is considered to be due probably to the influence of a specific virus.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00002.x
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  • 36
    Digitale Medien
    Digitale Medien
    Enteric redmouth bacterium: comparison of isolates from different geographic areas (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Characteristics of 18 strains of Yersinia ruckeri the causative agent of enteric redmouth disease, from a variety of hosts and a wide geographic range were compared. Except for variations in colonial morphology and in citrate, sorbitol, and trehalose reactions, the strains were morphologically and biochemically homogeneous. Sixteen strains reacted with antiserum against the first serotype reported, and one strain reacted with antiserum against a more recently reported serotype. One strain represented a third serotype. Evidence presented indicated that extension of the geographic range may not be entirely a result of the transport of carrier fish.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00039.x
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  • 37
    Digitale Medien
    Digitale Medien
    The histopathology of Stephanochasmus baccatus Nicoll, 1907 in the digestive gland of Buccinum undatum (L.) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Samples of Buccinum undatum (L.), a marine carnivorous prosobranch, from the Loch Ewe area of the West Coast of Scotland were found to be infected with the larval stages of Stephanochasmus baccatus Nicoll, 1907. The digestive glands of infected and uninfected molluscs were examined histologically and the pathogenesis of the larval stages in the digestive gland are described. Two types of lesion were found to occur. In Type I lesions degenerative changes were confined to individual tubules and neighbouring tubules remained unaffected. The Type I lesion was the typical response to the presence of the parasite in the digestive gland. The Type II lesion was less common and was associated with very heavy infections in the early part of the molluscan cycle of infection. In these molluscs large areas of the digestive gland were destroyed, and there was a marked cellular infiltrate of putatively inflammatory cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00024.x
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  • 38
    Digitale Medien
    Digitale Medien
    Mass mortality among minnows Phoxinus phoxinus (L.) in Lake Tveitevatn, Norway, due to an aberrant strain of Aeromonas salmonicida (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Mass morality in minnows Phoxinus phoxinus (L) was investigated in the Vinje water system, southern-central Norway. The main clinical feature was the development of extensive haemorrhagic skin lesions from which was isolated a non-pigmented, fish-pathogenic strain of Aeromonas salmonicida.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00026.x
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  • 39
    Digitale Medien
    Digitale Medien
    Infectious pancreatic necrosis: isolation of virus from eyed eggs of rainbow trout Salmo gairdneri Richardson (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00030.x
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  • 40
    Digitale Medien
    Digitale Medien
    Intestinal lesions in grasscarp Ctenopharyngodon idella (Valenciennes) infected with Balantidium ctenopharyngodonis Chen. (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. The protozoan Balantidium ctenopharyngodonis is a: common intestinal commensal of two-summer and older grasscarp, hut it may occasionally become pathogenic under the influence of certain predisposing factors. Outbreaks of enteritis complicated by excess multiplication of balantidia occurred among the two-summer and three-summer grasscarp stock in two pond farms during the autumn and winter. Fishes in the terminal stage of disease showed hyperaemia and inflammation of the mucosa over the entire gut. In the posterior 10–12 cm of the gut a dense creamy exudate coated the mucosa. Large numbers of balantidia were found in the exudate and between the mucosal folds there were excoriations, the size of a pin-head, obviously caused by the parasites. Histological examination revealed a loss of superficial epithelium and ulcerations in the grooves between folds.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00015.x
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  • 41
    Digitale Medien
    Digitale Medien
    Histopathology of furunculosis in brown trout Salmo trutta L. (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. A histopathological description is given of 2 naturally-occurring outbreaks of furunculosis in brown trout, one sub-acute, the other chronic. The splenic ellipsoids were destroyed to a greater or lesser extent thereby leading to a collapse of vascular integrity of the organ. In chronically affected fish however, a proliferation of stromal cells including reticular sheath cells was additionally noted. Cardiac involvement was the most prominent feature of the chronically affected fish. The marked degree of destruction left little doubt that cardiac efficiency was very severely impaired.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00017.x
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  • 42
    Digitale Medien
    Digitale Medien
    Ultrastructural study of epitheliocystis organisms from gill epithelium of the fish Sparus aurata (L.) and Liza ramada (Risso) and their relation to the host cell (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Ultrastructural study of epitheliocystis organisms from gills of Sparus aurata (L.) and Liza ramada (Risso) revealed in each fish a new form of the organism which differed from epitheliocystis organisms previously described. In their size range, the presence of a plasma membrane, a trilaminated cell wall and a central nucleoid, these organisms resembled chlamydial organisms (PLT). However they differed from them in the following respects: in both species several morphological forms were recognized; hyphae or mycelium-like forms and individual units, not comparable to any of the successive units described for Chlamydia organisms. Both organisms were contained within an inclusion in the host cell, but in epitlieliocysts from S. aM7-ata apparently intracytoplasmic forms were also observed. Ultrastructural studies of the cytoplasmic wall of the epitheliocystis inclusion in S. aurata suggest that the epitheliocystis cyst remains contained in a single unruptured hypertrophied cell, while in i. ramada the final cyst is formed through the coalescence of several epithelial cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00019.x
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  • 43
    Digitale Medien
    Digitale Medien
    Cytological studies on a new species of rickettsia found in association with a phage in the digestive gland of the marine bivalve mollusc, Tellina tenuis (da Costa) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. The secretory cells of the digestive glands of up to 75% of Tellina tenuis from sheltered sandy beaches on the Scottish coast contained intracytoplasmic inclusion bodies consisting of microcolonies of a rickettsia-like organism. The development and morphology of these parasitic bacteria and the cytopathic effect on the host cells are described. These features closely resemble those of the genus Coxiella of the family Rickettsiaceae. It was possible to culture the organism in embryonated hens' eggs. Scattered particles and paracrystalline arrays of a virus were seen in association with the bacteria. This is believed to be the first description of a phage from a rickettsia.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00003.x
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  • 44
    Digitale Medien
    Digitale Medien
    Tissue reaction of the three-spined stickleback Gasterosteus aculeatus L. to infection with Glugea anomala (Moniez, 1887) (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Abstract. Studies on an experimental infection of the stickleback (Gasterosteus aculeatus L.) with the microsporidian Glugea anomala conducted until day 126 post infection confirmed that xenoparasitic formations typical of the intracellular development of this microsporidian were responsible for a marked tissue reaction in the host. After a single oral infection, xenoparasitic formations developed in the subepithelial connective tissue of the glandular part of the stomach. The course of xenoma development was asynchronous. Up to the ‘cyst’ stage (xenomas filled with mature spores), their growth and development caused a pressure atrophy in the surrounding tissue. Later, the response to the presence of the xenoparasitic formation was the development of a granulomatous inflammatory reaction. Locally, the host responded to the infection by phagocytosis of mature spores by locally derived macrophages. In massive infections, changes occurred in the subepithelial connective tissue of the glandular part of the stomach (often the complete disappearance of tubular glands), which may result in a permanent influence on the function of this organ.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00007.x
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  • 45
    Digitale Medien
    Digitale Medien
    Evidence for an oncovirus in swimbladder fibrosarcoma of Atlantic salmon Salmo salar L. (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 1 (1978), S. 0 
    Details
    ISSN: 1365-2761
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2761.1978.tb00012.x
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  • 46
    Digitale Medien
    Digitale Medien
    Archimedes' Neusis-Constructions in Spiral Lines (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00453.x
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  • 47
    Digitale Medien
    Digitale Medien
    A Note on Bartholin and the Problem of Debeaune (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00454.x
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  • 48
    Digitale Medien
    Digitale Medien
    Newton's Extremal Second Law (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00455.x
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  • 49
    Digitale Medien
    Digitale Medien
    Reviews (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Notizen: Reviews in this articles:Dieter Schuh, Untersuchungen zur Geschichte der tibetischen Kalenderrechnung.A. L. Donovan, Philosophical Chemistry in the Scottish Enlightenment.Carlo Paoloni, Storia del Metano. Die Werke von Jakob Bernoulli, Band 3 (bearbeitet von B. L. van der Waerden).
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00457.x
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  • 50
    Digitale Medien
    Digitale Medien
    Books Received (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00458.x
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  • 51
    Digitale Medien
    Digitale Medien
    René-Just Haüys Konzeption vom individuellen integrierenden Molekül, ihre Widerlegung, und seine Ansichten über kristallbildende Kräfte (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00456.x
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  • 52
    Digitale Medien
    Digitale Medien
    Le petit traité d'Isaac Argyre sur la ratine carrée (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00221.x
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  • 53
    Digitale Medien
    Digitale Medien
    Interpolation Schemes in Dastūr al-Munajjūn (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00222.x
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  • 54
    Digitale Medien
    Digitale Medien
    Electric Displacement and the Development of Optics after Maxwell (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00223.x
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  • 55
    Digitale Medien
    Digitale Medien
    Reviews (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Notizen: Neugebauer, O., A History of Ancient Mathematical Astronomy Diocles. On Burning Mirrors, ed. G. J. ToomerPaul Kunitzsch (Hrsg.). Ibn as-Salah. Zur Kritik der Koordinatenüberlieferung im Sternkatalog des Almagest.Millburn, John R., Benjamin Martin. Author, Instrument-Maker and “Country Showman”.W. H. Brock (ed.), Armstrong and the Teaching of Science 1880–1930.Yehuda Elkana (ed.), The Interaction Between Science & Philosophy, Atlantic Highlands N.J.Nicholas H. Steneck (ed.), Science and Society: Past, Present and Future.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00224.x
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  • 56
    Digitale Medien
    Digitale Medien
    Reprints and New Editions (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Centaurus 22 (1978), S. 0 
    Details
    ISSN: 1600-0498
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin , Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1600-0498.1978.tb00225.x
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  • 57
    Digitale Medien
    Digitale Medien
    IMMUNOGLOBULIN EVOLUTION: CHEMICAL STUDY OF CLAWED TOAD (XENOPUS LAEVIS) HEAVY AND LIGHT CHAINS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: NH2, terminal amino acid sequence determinations of clawed toad (Xenopus laevis) immunoglobulins indicate that approximately 30% of the heavy chains and less than 5% of the light chains have unblocked NH2 termini. The major amino acid sequence of the X. laevis 7S immunoglobulin heavy chains is the same as that of the 19S immunoglobulin heavy chains. Thus in the synthesis of the heavy chains, the VH genes coding for unblocked heavy chains can associate with CH genes of both the 19S and 7S classes. This association is particularly important in amphibians because, in contrast to mammals and birds, the majority of amphibian antibody-producing cells synthesize both 19S and 7S immunoglobulins and do not participate in the ‘genetic switch’ characteristic of lymphocyte differentiation in higher organisms. In X. laevis, the major amino acid sequence at the first twenty-four positions of the unblocked heavy chains shows approximately 54% difference from the prototype amino acid sequence of the mammalian VHIII subgroup. Thus, the VHIII gene(s) must have started to appear after the evolutionary divergence of the common ancestor of mammals and birds from the amphibian line. The amino acid composition of the X. laevis 7S immunoglobulin heavy chains differs from that of its 19S immunoglobulins as well as those of human IgG and IgA. These data support the concepts (a) that amphibian 7S and 19S immunoglobins belong to distinct classes and (b) that amphibian 7S immunoglobulin does not resemble mammalian IgG or IgA.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00665.x
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  • 58
    Digitale Medien
    Digitale Medien
    FAILURE TO FIND H-2-ASSOCIATED SUSCEPTIBILITY TO LCM DISEASE (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Nine strains of mice bearing five distinct H-2 genotypes were inoculated intracerebrally with LCMV. There was no association found between particular K or D allotypes and susceptibility to acute LCM disease.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00668.x
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  • 59
    Digitale Medien
    Digitale Medien
    RED BLOOD CELL ALLOANTIGENIC SYSTEMS IN THE RAT (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: A new alloantigenic system on red blood cells, Ag-S, is described: the Ag-S1 allele is present in the SHR strain, and all other strains tested possess the allelic Ag-S2 specificity. The Ag-C system, which was previously described using xenogeneic antisera, was shown to be an alloantigenic system. The appropriate strain combinations are needed to elicit detectable antibodies, and the variability of the antigenic strength of this system can lead to problems in histocompatibility (Ag-B, H-1) typing. The Ag-D system was explored using both allogeneic and xenogeneic antisera. All three red cell systems are not linked to each other and are not linked to Ag-B (H-1). They are not isoantigenic systems, at least in the classical sense, since a variety of normal rat sera did not contain agglutinating antibodies to these antigens. Antibodies raised in various strain combinations are haemagglutinating but are not cytotoxic. The three antigenic systems serve as useful markers in delineating strains and substrains, and a variety of inbred strains of animals were typed using these reagents.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00666.x
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  • 60
    Digitale Medien
    Digitale Medien
    THE EFFECT OF FOSTERING NUDE MICE WITH ALLOGENEIC MOTHERS ON SUBSEQUENT MORTALITY (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Mortality in nude mice fostered by allogeneic mothers was studied. The data failed to support the hypothesis that mortality was due to graft versus host disease resulting from the passage of immunocomponent cells to the young in the mothers' milk. It was apparent that there were significant differences in the ability of mothers of different strains to rear nude mice.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00670.x
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  • 61
    Digitale Medien
    Digitale Medien
    IMMUNOLOGICAL PROPERTIES OF THE HUMAN ALCOHOL DEHYDROGENASE (ADH) ISOZYMES (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Rabbit immune sera, raised against purified horse alcohol dehydrogenase (ADH) and against human β1β1 ADH isozyme, were found to react specifically against the enzyme. The antisera reacted against one or more common antigenic determinants of the ADH from primates and other mammals, indicating that common structures have been preserved in ADH over a long evolutionary period. The antisera did not react against Drosophila and yeast ADH.The human ADH isozymes coded by the three loci ADH1, ADH2 and ADH3, and the allelic variants, were immunologically indistinguishable. In contrast, the ‘anodal' form of human ADH showed no reaction with the immune sera, suggesting a separate evolutionary origin of this molecule. Results from the single radial diffusion test indicated that the high enzymatic activity of ‘atypical' human ADH was not associated with high concentrations of the enzyme protein.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00657.x
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  • 62
    Digitale Medien
    Digitale Medien
    IMMUNOPATHOGENICITY AND ONCOGENICITY OF MURINE LEUKAEMIA VIRUS: IV. ANTINUCLEAR ANTIBODY RESPONSE AND TUMOUR INDUCTION IN B10.A. RECOMBINANT MICE (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: The levels of murine leukaemia virus (MuLV) proteins p30 and gp70, antinuclear antibody (ANA), anti-soluble nuclear protein, anti-single-stranded DNA, anti-double-stranded DNA and anti-histone antibodies were measured in B10.A and B10.A recombinant mice neonatally infected with MuLV-Scripps (Lerner et al., 1972). The incidence and latency of lymphoma and the incidence of glomerulonephritis were also determined. The mice studied could be divided into high-responder and low-responder groups. Most of the high ANA antibody could be attributed to anti-histone antibody. High response was associated with the H-2b haplotype and recombinant strains on the B10 background which were identical at the I-A subregion derived from the H-2b parental stock. In contrast, low ANA response was associated with the I-A subregion derived from the H-2k haplotype. In all groups of virus-inoculated animals, most animals developed serum elevations of p30 and gp70 and at least 72% of the inoculated animals developed lymphomas. High serum p30 levels correlated inversely with latency and directly with gp70 values. From 4 to 28% of the animals in each virus-inoculated group had histological evidence of glomerulonephritis, although no clear genetic basis could be ascribed to the incidence of glomerulonephritis, serum p30 or gp70 levels, or latency of lymphoma development.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00669.x
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  • 63
    Digitale Medien
    Digitale Medien
    ORIGINAL H-2d AND FOREIGN H - 2k - LIKE ANTIGENS ARE INDEPENDENT ENTITIES ON A CHEMICALLY INDUCED SARCOMA (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: We have previously shown that a methylcholanthrene-induced sarcoma of BALB/c strain (C-1) expressed, in addition to its original H-2d antigens, foreign H-2k-like determinants. In the present study the relationship between H-2d and H-2k-like antigens was examined by in vitro and in vivo assays. Cultured tumour cells were exposed in the cold to either a monospecific (D-23, D-25, D-1) or polyspecific (BALB/c anti-C3Hf) alloantiserum directed to H-2k specificities and then used to absorb the cytotoxic activity of either monospecific (D-31) or a polyspecific (C3Hf anti-BALB/c) alloantisera to H-2d antigens (blocking test). The opposite was also done, i.e. tumour cells were coated with anti-H-2d sera and used to absorb the cytotoxicity of anti-H-2k sera. No reciprocal interference was found between the two H-2-different antigens in the absorption of related alloantisera. Suspensions of irradiated C-1 tumour cells were exposed in vitro to either anti-H-2d or anti-H-2k antisera and then used to immunize either syngeneic BALB/c or allogeneic C3Hf mice. The coating of immunizing neoplastic cells with BALB/c anti-C3Hf serum prevented anti-C3Hf (anti-H-2k) antibody production in BALB/c mice without affecting anti-BALB/c (anti-H-2d) antibody development in C3Hf animals; coating of H-2d antigens on tumour cells strongly reduced anti-BALB/c but not anti-C3Hf antibody production. Both in vitro and in vivo experiments indicated that foreign H-2k-like determinants are physically separated from the wild H-2d antigens on the C-1 sarcoma cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00658.x
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  • 64
    Digitale Medien
    Digitale Medien
    DETECTION AND CROSS-REACTION OF H-Y ANTIGEN BY HAEMAGGLUTINATION (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Haemagglutination has been developed for the detection of H-Y antigen and antibodies by using mouse and rat red blood cells (RBC). The method is simple, specific and sensitive. With this method, the H-Y antigen was demonstrated on the surface of RBC from mouse, rat, hamster, rabbit, cat, chicken, trout and man, as a cross-reactive surface component. RBC of the quail and the cat differed from the other species in their ability to absorb the H-Y antibodies, indicating unknown differences in the H-Y antigen of these species. The female trout was found to carry the H-Y antigen and thus is assumed to be the heterogametic sex of this species. Trout serum contains factor(s) with a potential for agglutinating mouse and rat RBC. Female mice (C57B1/6J) and rats (DA) were immunized with various male tissues according to different schedules. All H-Y antisera contained autoantibodies when tested by haemagglutination. The problems involving the detection of H-Y antigen and the effect of autoimmunity in H-Y antiserum are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00659.x
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  • 65
    Digitale Medien
    Digitale Medien
    GENETIC ANALYSIS OF THE MIXED LYMPHOCYTE REACTION IN H-1 SEROLOGICALLY IDENTICAL INBRED RATS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: H-1d and H-11 serologically identical combinations of inbred rat strains were studied, in which there was a strong mixed lymphocyte reaction (MLR). The H-1d identical combination was formed with the Maudsley reactive (MR) and BD IX strains, in which there was bidirectional stimulation. The LAD differences in the combination BD IX and MR were shown in experiments using back-crosses derived from two different sources, BD IX x LEW and MR x LEW.The H-11 identical combination was the F344 (Fisher) and LEW (Lewis) strains; here the MLR was unidirectional—LEW stimulating F344. Two other H-11 serologically identical strains, AS and HCS, also stimulated F344 lymphocytes. Genetic segregation analyses using back-crosses showed linkage with H-1 in both instances. The LADs of AS, HCS and LEW appeared to be the same.These experiments show that the rat LADs so far detectable using these strains are all encoded by genes linked to the major histocompatibility system of the rat, despite serological identity. In addition to disassociation of the major histocompatibility system antigens detected by serological means and those defined by MLC testing, there was also disassociation of transplantation antigens as shown in the BD IX x MR model.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00661.x
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  • 66
    Digitale Medien
    Digitale Medien
    EVIDENCE FOR A POSSIBLE MAJOR HISTOCOMPATIBILITY COMPLEX (BLA) IN CATTLE (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Lymphocytotoxic sera have been produced in forty-seven cattle following skin grafting or lymphocyte immunization between dam-offspring pairs. From these sera seventy antilymphocyte reagents have been produced. Seven of the sera were operationally monospecific without absorption, thirty-seven others were made operationally monospecific and twenty-six partially purified by absorption with lymphocytes. Thirty-five of these sera were used in France and an additional thirty-five were used in Scotland.The inheritance of the antigenic factors detected by these sera has been studied in 480 cattle families and the evidence is consistent with the hypothesis that at least seventeen of the factors are inherited in a simple Mendelian fashion. Fourteen of these factors show evidence of linkage with at least one other factor and are likely to be controlled by a limited number of closely linked loci. It is suggested that these loci should be identified as the BLA region.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00662.x
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  • 67
    Digitale Medien
    Digitale Medien
    GENETICS OF SUSCEPTIBILITY TO EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS STUDIED IN THREE RAT STRAINS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: A genetic analysis has been performed on susceptibility to experimental autoimmune encephalomyelitis using three strains of rats: one susceptible strain (Lewis) and two nearly resistant strains (Fischer and PVG). The (LEW x F)F1 hybrid is highly susceptible, the (LEW x PVG)F1 hybrid nearly resistant. Backcross analysis demonstrates that susceptibility cannot be solely explained by a gene linked to the AgB complex, especially not in the Lewis-PVG combinations. A hypothesis is presented where susceptibility is regulated by a susceptibility gene linked to the AgB complex and a resistance gene which is not linked to that complex.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00663.x
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  • 68
    Digitale Medien
    Digitale Medien
    MEMBRANE ANTIGENS RECOGNIZED BY HETEROANTISERA AGAINST MOUSE TUMOURS, TESTED IN CELL LINES OF DIFFERENT H - 2 HAPLOTYPES (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: The pattern of reactivity of two heteroantisera against mouse tumour cells (rabbit anti-Meth A sarcoma: RAMA; and rabbit anti-RBL-5 leukaemia: RAR-5) has been studied in various cell lines of different H-2 haplotypes in complement-dependent cytotoxicity tests using a microadioassay.RAMA was cytotoxic not only for Meth A (H-2d) but also for MCG4, P815Y, LSTRA, YC8 (H-2d), L929, TLC5, Gardner (H-2k), RBL-5 and TLX/9 (H-2b). RAR-5 similarly killed RBL-5, as expected, as well as Meth A, P815Y, MCG4, SL2, YC8, LSTRA (H-2d), L929 (H-2k), TLX/9, MBL2, Gil IV, EL4 (H-2b) and YAC (H-2a).The cross-cytotoxicity RAMA-RBL-5 and RAR-5-Meth A was abolished when RAMA or RAR-5 were absorbed with allogeneic tissues from C57B1/6, BALB/c, CBA/H, C57B1/10 (B10), B10.BR, B10.D2, but not with rat lymphoid cells. A species-specific antigen present in these strains of mice thus appeared to be responsible for this cytotoxicity.The direct killing obtained with RAMA on Meth A and RAR-5 on RBL-5 was not absorbed by: (a) allogeneic cells of C57B1/6, CBA/H, AKR, B10, B10.BR, B10.D2 for RAMA, and CBA/H, BALB/c, B10, B10.BR, B10.D2 for RAR-5; or (b) syngeneic normal lymphoid cells (BALB/c and C57B1/6 respectively).This suggests the presence of a heteroantibody in the sera recognizing structures at the tumour cell surface that are absent in normal lymphoid cells—a tumour-specific antigen (TSA).Finally, the TSA of Meth A (recognized by BALB/c-absorbed RAMA) did not cross-react with eight mouse cell lines of different aetiology and origin: MCG4, P815Y, Gardner, TLC5, L929, TLX/9, LSTRA and RBL-5. However, the TSA of RBL-5 (recognized by C57B1/6 absorbed RAR-5) reacted not only with RBL-5 but also with tumour cells induced by viruses antigenically related to Rauscher, belonging to the group FMR Gi. It reacted also with EL4, a tumour cell line not virus induced, and weakly with SL2, a spontaneous tumour cell line. It did not react with TLX/9 (X-ray induced) or Meth A (chemically induced).From these results it is concluded that heteroantisera against mouse tumour cells recognize at least species-specific antigens and tumour-specific antigens.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00660.x
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  • 69
    Digitale Medien
    Digitale Medien
    Editorial Note (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00664.x
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  • 70
    Digitale Medien
    Digitale Medien
    INHERITED ‘MOSAICISM’ WITHIN THE ABO BLOOD GROUP SYSTEM (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: A family with examples of the rare condition known as ‘inherited mosaicism affecting the ABO blood groups’ has been studied. In this family there were five examples of Bmos:O mosaicism. Blood group gene-specified transferase estimations were studied in this condition for the first time. In ‘affected' members, levels of B gene-specified transferease were low, and amounted to only 7-10% of the activity of a normal control. It is proposed that Bmos is correctly classified as a new form of weak B.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00649.x
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  • 71
    Digitale Medien
    Digitale Medien
    α-N-ACETYL-d-GALACTOSAMIYL- AND α-d-GALACTOSYLTRANSFERASE ACTIVITIES IN SERA OF CIS AB BLOOD GROUP INDIVIDUALS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Thirteen cis AB persons from five families were examined for serum glycosyltransferase activities associated with the biosynthesis of A and B blood group characters. Their transferases were generally homogeneous within one family, except for A2/cis AB genotypes, whose A enzyme level was similar to the A2 normal sera, but they varied from one family to another. These activities differed quantitatively and qualitatively from A, B and AB normal sera. Studies of A transferase showed variations in the pH-dependent curve, the effect of cofactors and the capacity of conversion of O red cells into A-active cells. Moreover, A and B transferases behaved differently with respect to their relative levels than did AB heterozygous normal sera. The results were discussed and it was suggested that a mutation of a single enzyme transferring both galactose and N-acetyl-galactosamine could explain these properties.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00650.x
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  • 72
    Digitale Medien
    Digitale Medien
    THE EFFECT OF ENZYMES ON THE BLOOD FACTORS ASSOCIATED WITH THE FV SYSTEM OF BOVINE ERYTHROCYTES (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Treatment of cattle red cells (CRC) with proteases and neuraminidase revealed at least one trypsin- or pronase-sensitive type and a protese-resistant type of sialoglycoprotein.The antigen F itself and the antigen IM in the F/F and F/V type of CRC were associated with the protease-resistant glycoprotein. Moreover, they were demonstrable in the agglutination test, but only after treatment with proteases. The antigen V, allelic to F, was, however, associated with a pronase-sensitive protein and the antigen IM in the V/V type of CRC with a trypsin- or pronasesensitive glycoprotein. The antigen N′ was inactivated by chymotrypsin or pronase, irrespective of whether it was transmitted with the F or with the V.While the antigens IM, N′ and the antigen reacting with rabbit serum, in addition to the antigen F in the F/F type of CRC, showed no or only very weak (titre 1:2) reactions, these same antigens, in addition to the antigen V in the V/V type of CRC, all showed high titres (1: 32 to 1: 128) in the anti-globulin test.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00651.x
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  • 73
    Digitale Medien
    Digitale Medien
    PRIMING POTENCY OF THE PRODUCTS OF INDIVIDUAL REGIONS OF THE H-2 COMPLEX AND THEIR ROLE IN THE RESTIMULATION IN SECONDARY MLC (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Genetic analysis of the determinants causing an early proliferation in MLC after priming with allogeneic cells in vivo was performed. The active determinants were localized in the I-A subregion of the H-2 complex by using appropriate recombinant mouse strains.Upon priming with antigens coded by the whole H-2 complex, the lymphocytes gave a strong MLC response only to the priming stimulator cells and cells sharing the I-A subregion determinants of the latter. The response to third party stimulator cells and cells not sharing I-A subregion determinants was low.Upon priming with various H-2 region products, only lymphocytes primed against I-A subregion products gave an early proliferative MLC response to the priming stimulator cells, whereas lymphocytes primed against other H-2 region products gave none.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00652.x
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  • 74
    Digitale Medien
    Digitale Medien
    ABSENCE OF VARIATION IN HUMAN C5 (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00656.x
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  • 75
    Digitale Medien
    Digitale Medien
    HISTOCOMPATIBILITY DIFFERENCE BETWEEN C3HfeB/HeN AND C3H/HeN MICE: TUMOUR INDUCED IN C3HfeB/HeN MICE EXPRESSES C3H/HeN-ASSOCIATED ALLOANTIGEN (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: A transplacentally induced lung tumour of C3HfeB/HeN mouse origin expresses, as a tumour-associated antigen, a normal tissue component of strain A mice. The genetic locus coding for this alloantigen has been shown to be linked to the H-2 major histocompatibility complex. In the present study we demonstrate that this antigen is also expressed on normal tissues of C3H/HeN mice. Skin grafts exchanged between C3HfeB/HeN and C3H/HeN mice are reciprocally rejected at approximately 3 weeks after grafting. C3HfeB/HeN mice were derived from C3H/HeN mice in 1945. These strains have apparently deviated since then in their genetic regulation of the expression of the MHC-linked genetic locus. The finding of the C3H/HeN-associated antigen on a C3HfeB/HeN mouse-derived lung tumour indicates that this deviation is reversible.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00653.x
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  • 76
    Digitale Medien
    Digitale Medien
    IMMUNOCHEMICAL INVESTIGATIONS ON WATER FROG EGGS: COMPARATIVE STUDIES ON RANA RIDIBUNDA, RANA LESSONAE AND THEIR HYBRID RANA ESCULENTA (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Eggs of Rana ridibunda, Rana lessonae and their hybrid Rana esculenta were examined for their immunochemical properties. The reaction spectra obtained confirm the hybrid origin of Rana esculenta.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00655.x
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  • 77
    Digitale Medien
    Digitale Medien
    COMPARISON OF THE HAPLOTYPES OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE RAT (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Two haplotypes which posed difficult problems in serological identification, those of the HW and MNR/N strains, were studied. The HW strain was originally described as a unique haplotype (H-1h), but breeding difficulties precluded its detailed serological analysis. The red blood cells of the HW strain agglutinate weakly and cross-react with antisera to the Ag-B8 group. Anti-HW antisera cross-react strongly with LEW, ACI and WKA, but absorption with these strains did not produce an adequate typing serum. By judicious selection of recipients, however, an appropriate typing reagent could be made; a particularly useful one was (BUF × MR)F1 anti-HW absorbed with WKA red blood cells. The HW haplotype segregated appropriately in a (DA × HW)F2 population. The HW strain is a low responder to poly (Glu52Lys33Tyr15). The H-1h haplotype of this strain was designated Ag-B12.The MNR/N strain had not previously been studied serologically, although its MLR type had been defined as H-1c (MLR-5). Antisera to MNR/N crossreacted strongly with the H-1a, b, d, f haplotypes, but MNR/N red blood cells agglutinated only weakly with many antisera. An operationally monospecific reagent antiserum to the MNR/N haplotype could not be made. The uniquencess of the MNR/N haplotype was shown by F1 tests with LEW.1A, LEW.1D and LEW.1F, by various serological analyses, including production of antisera against MNR/N and in the MR strain; by segregation studies with (LEW × LEW.1D)N5 and (DA × DA.MNR)N4 segregating back-cross populations, and by grafting skin from (DA × DA.MNR)N4 homozygous and heterozygous animals to DA recipients. The MNR/N strain is a high-responder to poly (Glu52Lys33Tyr15). The MNR/N haplotype of this strain was designated Ag-B13 (H-1m). The data led to the working hypothesis that the MNR/N strain may be a recombination between the A region of H-1d and the B region of H-1c. In addition, the H-1d private specificity at the A region was probably lost by a deletion mutation which left the main complex of public specificities intact.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00654.x
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  • 78
    Digitale Medien
    Digitale Medien
    IMMUNOGLOBULIN ALLOTYPES IN AFRICAN POPULATIONS: I. Gm-Am HAPLOTYPES IN A NIGERIAN POPULATION (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00639.x
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  • 79
    Digitale Medien
    Digitale Medien
    INHERITED STRUCTURAL VARIATION AND LINKAGE RELATIONSHIPS OF C7 (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Three structural forms of C7 have been distinguished by isoelectric focusing. They are the products of three co-dominantly expressed alleles at an autosomal locus. The C7 locus is close to that for C6, but is not close to the HLA complex.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00641.x
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  • 80
    Digitale Medien
    Digitale Medien
    X CHROMOSOME COMPLEMENT AND SERUM LEVELS OF IgM IN MAN AND MOUSE (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: The levels of IgM were measured in sera from mice with different chromosome complements, including 39, XO mice and phenotypically male mice bearing the sex-reversed gene (Sxr) (XX,Sxr/+ and XY,Sxr/+).The mean values of IgM were found to be higher in normal female mice than in the males belonging to two different strains. This is in agreement with the higher mean serum levels of IgM observed in two groups of sera from normal human females and males.However, while we could confirm that the mean level of IgM was lower in 45, XO women than in normal females and comparable to the mean value of normal males, the same effect was not seen in 39, XO mice. In fact, the mean concentration of serum IgM in 39, XO mice was similar to that in normal females. Furthermore, it was observed that the mean values of serum IgM in the two groups of sex-reversed male mice (XX,Sxr/+ and XY,Sxr/+) were also not statistically different from those in normal males.Thus the role that the number of X chromosomes plays in the control of the serum levels of IgM is different in man and the mouse, in agreement with the observed different phenotypic manifestations, and in particular with the hormonal situations existing in X chromosome abnormalities in these two species.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00640.x
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  • 81
    Digitale Medien
    Digitale Medien
    HLA ANTIGENS AS POSSIBLE MARKERS OF HETEROGENEITY IN SCHIZOPHRENIA (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: The distribution of HLA-A-, -B- and -C-locus antigens was tested in 200 male patients with final diagnosis of schizophrenia. A significant increase of HLA-A28 and HLA-Cw4 antigens and haplotype A10-B18 was found. Indications were obtained for the increase of HLA-Al in hebephrenic patients.It was presumed that the increase of Cw4 represents the common denominator of the diverse findings on paranoid schizophrenia. The increase of Cw4 indicates that the paranoid schizophrenia disease susceptibility locus is either the C locus itself or another closely linked locus (or loci). This would stress the importance of the HLA ‘central' regions for HLA and disease associations.A hypothesis is presented which points to the possibility that HLA antigens could be genetic markers of three ethiopathogenetic subgroups of schizophrenia. The possible tests of this hypothesis are also suggested.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00642.x
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  • 82
    Digitale Medien
    Digitale Medien
    SLB, A NEW ALLOANTIGENIC SYSTEM OF THE PIG (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: An alloantigen segregating in the double back-cross families, distinct from serologically determinable transplantation antigens controlled by the major histocompatibility complex (SLA), was detected in pigs by the complementdependent lymphocytotoxic technique. The system was designated SLB and its product (antigen SLB-Al) was demonstrated in all lymphocytes from the lymph nodes, thymus and peripheral blood, but not in the erythrocytes. Back-cross matings supplied evidence of the dominant heredity of SLB-Al. Detection of further SLB antigens was unsuccessful, so that only two alleles (SLB-Al and SLB-A-) could be determined in families. Double back-cross families revealed a close linkage between the SLB locus and the L blood group locus. Maximum lod score values were calculated in recombination fraction θ= 0.10.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00643.x
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  • 83
    Digitale Medien
    Digitale Medien
    PLACENTAL AND FOETAL WEIGHT IN THE NUDE MOUSE (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Placental and foetal weight and litter size were studied on the 18th day of pregnancy in the athymic nude mouse. Placental weight and litter size were unaffected by the absence of a thymus. Foetal weight was reduced, probably as a result of the health status of such animals.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00645.x
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  • 84
    Digitale Medien
    Digitale Medien
    ASYMMETRY IN THE SEROLOGICAL RESPONSE AND MIXED LYMPHOCYTE REACTIONS BETWEEN C57B1/6 AND THE CONGENIC MUTANT C57B1/6. CH-2ba [H(Z1)] (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Asymmetry in the relationship between the H-2K mutant strain C57B1/6. CH-2ba (H-2ba) and the wild-type congenic C57B1/6 has been demonstrated both in MLR and serologically by haemagglutination. MLR between these strains, when B6 was the responder, was as strong as that toward allogeneic stimulator cells: H-2ba was regularly less responsive toward B6. Responses in both directions were increased, in terms of augmented proliferative responses, by prior immunization. In this context the MLR resembles that towards minor H-locus antigens rather than those controlled by the H-2 locus. Immunization of (H-2ba× BALB/c)F1 hybrids with B6 lymphoid cells induced the production of a haemagglutinating antibody not directed toward any known H-2 specificity. The B6 haemagglutinogen, termed He, was present on B6 lymphoid as well as red blood cells. Segregation studies of F2 and back-cross progeny of (H-2ba x BALB/c)F1 hybrids suggest that the response to He is controlled by two Ir genes, one of which is linked to H-2.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00644.x
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  • 85
    Digitale Medien
    Digitale Medien
    Reply (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00648.x
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  • 86
    Digitale Medien
    Digitale Medien
    Letter to the Editor (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00647.x
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  • 87
    Digitale Medien
    Digitale Medien
    PARTIAL PURIFICATION AND CHARACTERIZATION OF THE INHERITED H1 1 AND R 67 ANTIGENS OF RABBIT SERUM HIGH DENSITY LIPOPROTEIN (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Purification and characterization of the Hl 1 antigen revealed a polypeptide with molecular weight of 20,000 by gel filtration. The peptide contained 20% neutral sugar and 4.5% neuraminic acid. Amino acid analysis as well as the Nterminal sequence for thirteen amino acid residues and three C-terminal amino acids were determined. Difference index analysis gave an indication that the H1 1 polypeptide is unique.Purification of R 67 antigen did not give a pure polypeptide in sufficient amount to do chemical analysis. A crude fraction of R 67 antigen had three bands on SDS-PAGE, all with R67 antigenic activity. The crude fraction contained 10% neutral sugar and 3.5% neuraminic acid. No N- or C-terminal amino acids could be determined for the crude fraction of R 67 antigen.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00633.x
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  • 88
    Digitale Medien
    Digitale Medien
    TEMPERATURE STRESS AND IMMUNITY IN MICE: EFFECTS OF ENVIRONEMTAL TEMPERATURE ON THE ANTIBODY RESPONSE TO HUMAN IMMUNOGLOBULIN OF MICE, DIFFERING IN AGE AND STRAIN (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Physiological responses at different ambient temperatures and temperature-dependent changes in immune responsiveness are polymorphic. At 4d̀C, the antigen elimination from the bodies of SJL and C57B1/6 mice is accelerated. In SJL, but not in C57B1/6 mice, the half-life of antigen elimination decreased between the ages of 3 and 11 weeks. Parental mice and their F1 hybrids showed a fall in rectal temperature, which was greatest in young animals. Hypothermia was greater in C57B1/6 than in SJL and F1 hybrids; in 3 week old C57B1/6 it resulted in high mortality. The response to aggregated human immunoglobulin (HGG) was evaluated by (a) the number of animals with detectable antibody, (b) the minimal dose of antigen eliciting detectable antibody, and (c) the mean titre of haemagglutinating antibody. SJL mice were more responsive than C57B1/6 mice. Low antibody formation in the secondary response was dominant, i.e. the amount of antibody produced by (SJL × C57B1/6)F1 mice was the same as that produced by the parental C57B1/6 strain. In a primary response, the quantity of antibody varied with the age of the immunized animal; 18 week old mice responded to lower minimal doses of antigen and produced more haemagglutinating antibody than 3 week old animals.After a second injection with HGG, SJL but not C57B1/6 mice produced more antibody when kept at 14d̀C rather than at 22d̀C or 30d̀C, and produced the lowest antibody titres when kept at 4d̀C. The relation between ambient temperature and the response of the SJL mice was dominant over that of the C57B1/6 strain.Primary differed from secondary responsiveness in that neither strain produced significantly lower titres when ambient temperature fell to 4d̀C; only 18 week old SJL mice responded with a marginal decrease in peak antibody production.The described polymorphism may affect both the individual capacity to cope with low temperatures and the evolutionary adaptation of a species to climatic extremes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00646.x
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  • 89
    Digitale Medien
    Digitale Medien
    STUDY OF THE α-N-ACETYLGALACTOSAMINYLTRANSFERASE IN SERA AND RED CELL MEMBRANES OF HUMAN A SUBGROUPS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: The product of the A blood group gene in the erythrocyte membrane and serum from ‘weak A’ variants was investigated using low and high molecular weight acceptors and compared with common A1 and A2 blood samples. A reduced enzyme activity was detected, but only in some of the A variants, namely the A3 (eight out of eleven), Am or Ay samples. Other sera from A3 (three out of eleven), Ax, Aend or Ael individuals were apparently devoid of enzyme activity.A kinetic study by temperature inactivation of A blood group sera also showed that A enzymes are more labile than B enzymes from BI or BII sera. Moreover, in one case (A3 sample Del.), a very fast inactivation of the A enzyme was observed, suggesting the occurrence of a variant enzyme qualitatively different from the others so far studied.The erythrocyte membrane preparations from all A variants contained no detectable A enzyme activity except for the A1 and A2 samples, the former being three to five times more active than the latter. The B enzyme activities from four samples of B RBC tested were comparatively stronger than the A enzyme activity of A1 RBC.The results were discussed and it was suggested that the synthesis and/or the secretion of the A enzyme in the organism is not uniform from one tissue to another, but could depend on which of the ‘weak A’ alleles or modifier genes is involved.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00635.x
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  • 90
    Digitale Medien
    Digitale Medien
    THE cis AB PHENOTYPE IN THREE GENERATIONS OF ONE FAMILY: SEROLOGICAL, ENZYMATIC AND CYTOGENETIC STUDIES (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: The blood from three individuals belonging to consecutive generations of one family were characterized as cis AB on the basis of (a) the serological behaviour of the B antigen on their red cells, (b) the presence of weak anti-B in their sera and (c) family studies, which unequivocally demonstrated the genotype AB: O for two of the individuals with atypical AB groups.The serological behaviour of the A antigen on the red cells was intermediated between that of normal A1 and A2 cell. The B antigen gave weak and variable reactions with naturally occurring antibodies. Treatment of the cis AB red cells with an α-galactosyltransferase in the serum from an A1B individual rendered them agglutinable by the normal range of anti-B sera, demonstrating that the red cells do not lack precursors for the formation of normal B-active structures.The cis AB sera all contained relatively strong α-N-acetylgalactosaminyl-transferases which had pH optima of 6.0, characteristic of A1 gene-specified enzymes. The affinity of the enzymes for UDP-galactose, as measured by the apparent Ki, appeared to be greater than that of the A transferases in normal A1 and A1B sera. The B-gene transferases in the cis AB sera were very weak and were more readily inhibited by UDP-N-acetylgalactosamine than were the α-galactosyltransferases in normal B and AB sera. Both the A- and B-transferase activities in the cis AB sera are, therefore, in some ways different from the corresponding enzyme activities in the sera of normal A, B or AB donors.Cytogenetic study of blood lymphocytes from all three individuals showed normal karyotypes. Specifically, the terminal bands of the long arms of the No. 9 chromosomes, to which the ABO:Np-1: AK-1 linkage group has been assigned, displayed G bands similar to those in cells from other (normal) individuals examined simultaneously.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00634.x
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  • 91
    Digitale Medien
    Digitale Medien
    STUDIES ON THE MEMBRANE GLYCOPROTEIN DEFECT OF En (a-) ERYTHROCYTES (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Sodium dodecylsulphate polyacrylamide gel electrophoretic methods and quantitative analyses of the N-terminal amino acids were applied to the sialoglycoprotein mixture and glycoprotein fractions from normal erythrocyte membranes, as well as preparations from red cells of individuals belonging to the English and Finnish En(a-) families. The data confirm the observation by alternative methods that SS cells exhibit a higher Ss glycoprotein content than ss erythrocytes. The results of end-group analyses suggest that the N-terminal amino acids serine and leucine represent the structures differentiating the MN and the ‘M’ and ‘N’ antigens on the MN and Ss glycoproteins respectively. Data from peptide sequence analyses confirm that the glycine/glutamic acid polymorphism at the fifth position of the MN glycoprotein's peptide chain is closely or absolutely linked with the serine/leucine polymorphism at its N-terminal position. As normal (EnaEna) red cells exhibiting ‘M’ antigenic properties have not been detected, the hypothesis is proposed that the Ss glycoprotein of English En(a-) erythrocytes possesses an MN-Ss hybrid polypeptide chain analogous to those of the δ-β Lepore haemoglobins.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00636.x
    Standort Signatur Erwartet Verfügbarkeit
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  • 92
    Digitale Medien
    Digitale Medien
    MEASLES ANTIBODIES AND HLA (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Blood samples were collected from healthy twin pairs of the same sex, living in the same households and attending the same schools. The occurrence of HLA antigens and seven red cell antigens was determined. The serum titres of antibodies against three different components of measles virus were measured by haemagglutination inhibition, by haemolysis inhibition and by nucleocapsid complement fixation tests. The variability of titres within twin pairs was significantly greater among seventy dizygotic twins than among seventy monozygotic twins, suggesting an influence of genetic factors on the measles antibody response. However, no evidence for a genetic linkage between HLA loci and the loci involved in the antibody response was apparent, since the variability of antibody titres among eighteen dizygotic pairs with common HLA haplotypes was about similar to that among twenty-three pairs with different haplotypes. A possible association between antibody titres and HLA-A3 and B7 antigens was also analysed in the present material. The comparisons were made between groups of single individuals in the twin pairs. The presence or absence of HLA-A3 antigen did not significantly influence the mean titres of groups. However, in two out of six comparisons, the mean antibody titre was significantly higher in the group of individuals who had HLA-B7.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00637.x
    Standort Signatur Erwartet Verfügbarkeit
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  • 93
    Digitale Medien
    Digitale Medien
    PRESENCE OF SLA AND Ia-LIKE ANTIGEN ON BOAR SPERMATOZOA (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Several parameters for serological tests on boar spermatozoa were studied, and a reliable technique was developed and employed. Using SLA (the MHC system in pig) genotyped boars, and specific reagents, SLA and Ia-like antigens were demonstrated on the sperm using both the cytotoxic and the absorption test. No SLA activity was detected in the seminal fluid.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00638.x
    Standort Signatur Erwartet Verfügbarkeit
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  • 94
    Digitale Medien
    Digitale Medien
    A CAUCASOID PEDIGREE DEMONSTRATING THE TRANSMISSION OF A Gm1, 2, 17; 5, 13, 14 HAPLOTYPE (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Data illustrating the inheritance of a Gm1, 2, 17; 5, 13, 14 haplotype in a Caucasian family are presented. The mother and two children are heterozygous for this unusual haplotype. The possible origin of the haplotype is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00624.x
    Standort Signatur Erwartet Verfügbarkeit
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  • 95
    Digitale Medien
    Digitale Medien
    THE DISTRIBUTION OF THE INHERITED Hl 1 AND R 67 ANTIGENS ON RABBIT SERUM HIGH DENSITY LIPOPROTEIN (HDL) PARTICLES (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Qualitative and quantitative analysis of the distribution of Hl 1 antigen and R 67 antigen on high density lipoprotein (HDL) particles were conducted on six rabbit sera. The Hl 1 antigen showed non-identity with A-I-containing HDL particles, and antiserum to Hl 1 did not remove A-I-containing HDL particles. The R 67 antigen showed partial identity with A-I-containing HDL particles. Antiserum to R 67 antigen removed 30–40% of A-I-containing HDL particles from the sera of animals which were heterozygous for R 67, and 65% of the A-I-containing HDL particles from the serum of one R 67 homozygous animal.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00626.x
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  • 96
    Digitale Medien
    Digitale Medien
    PURIFICATION AND PARTIAL CHARACTERIZATION OF THE apoA-I OF RABBIT HIGH DENSITY LIPOPROTEIN (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Purfication of apoA-I from rabbit high density lipoproteins (HDL) gave one single band in sodium dodecylsulphate-polyacrylamide disc electrophoresis and reacted only with antiserum to apoA-I. The molecular weight was about 25000. The amino acid composition of rabbit apoA-I gave a difference index of 7.4 compared to human apoA-I and of 6.5 compared to dog apoA-I. Of the three carboxy terminal amino acid residues the rabbit protein has one in common with the dog.The amino acid sequence of twenty-nine amino terminal residues showed 62% homology with the human protein; a minimum of thirteen base changes were required in the DNA sequences that encoded these two proteins. When the same sequence was compared with dog apoA-I, it was found that ten base changes would be sufficient to account for the differences between the proteins.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00625.x
    Standort Signatur Erwartet Verfügbarkeit
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  • 97
    Digitale Medien
    Digitale Medien
    EVIDENCE THAT BLOOD GROUP A ANTIGEN ON LYMPHOCYTES IS DERIVED FROM THE PLASMA (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Serum from group O volunteers, who had been injected with porcine A blood group substance, was used in lymphocytotoxicity tests. Positive reactions were obtained only with lymphocytes of group A secretors; the strongest reactors were Le(a-b-). The same group O sera reacted with group O lymphocytes which had been exposed to a glycosphingolipid fraction prepared from the plasma of A, Le(a-b-) secretors. These reactions were specifically inhibited by A substance. It is suggested that, unlike the A antigen on red cells, the A antigen detected in lymphocytotoxicity tests is entirely derived from the plasma.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00627.x
    Standort Signatur Erwartet Verfügbarkeit
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  • 98
    Digitale Medien
    Digitale Medien
    COMPLEMENT FIXATION ANTIBODIES TO GLYCOSPHINGOLIPIDS IN SERA OF RARE BLOOD GROUP p AND Pk PHENOTYPES (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Blood group P antigen and Pk antigen were recently identified as glycosphingolipid globoside, GalNAc(β, 1→3)Gal(α, 1→4)Gas(β, 1→4)Glc(β, 1→1)ceramide, and trihexosylceramide, Gal(α, 1→4)Gal(β, 1→4)Gld(β, 1→1)ceramide, respectively (Naiki & Marcus, 1974). The presence of antibodies to both antigens in the sera from rare p donors and antibodies to P antigen in the serum from a rare Pk donor were first demonstrated by the complement fixation test with the optimal antigen preparations containing each purified glycolipid, lecithin and cholesterol. In the serum from a p donor, most of antibody population of anti-P was IgM and was cross-reacted to Forssman glycolipid, GalNAc(α, 1→3)GalNAc(β, 1→3)Gal(α, 1→4)Gal(β, 1→4)Glc(β, 1→1) ceramide, but the rest of the anti-P antibodies and most of anti-Pk antibodies were IgG and had marked specificities for globoside and trihexosylceramide, respectively.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00628.x
    Standort Signatur Erwartet Verfügbarkeit
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  • 99
    Digitale Medien
    Digitale Medien
    INTERCELLULAR ADHESIVENESS OF H-2 IDENTICAL AND H-2 DISPARATE CELLS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Using a 2 times 2 design, the collection rates of cells from radioactively labelled single-cell suspensions on cell-coated collecting surfaces were tested for a possible H-2 effect on intercellular adhesiveness. By a statistical procedure, the undesirable variability in the suspension and/or in the collecting surface could be eliminated, and the H-2 specific net effect estimated. In this way it was possible to detect (even on the background of a large non-specific variability) significant reductions of the allogeneic collection rates (i.e. between cells which differed only in their H-2 haplotypes) as compared to the syngeneic standards. It is concluded that cells of a given H-2 haplotype have preferential adhesiveness to syngeneic cells.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00629.x
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  • 100
    Digitale Medien
    Digitale Medien
    INFLUENCE OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE PIG (SLA) ON SERUM HAEMOLYTIC COMPLEMENT LEVELS (1978)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 5 (1978), S. 0 
    Details
    ISSN: 1744-313X
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Biologie , Medizin
    Notizen: Sera from fourty-six non-congenic adult pigs from one inter-related herd were tested for their haemolytic serum complement levels. A comparison of these data with the major histocompatibility complex (SLA) genotypes of these animals resulted in the demonstration of highly significant differences in lytic activity between sera obtained from animals of two distinct SLA haplotypes. These data showed a high correlation between the SLA complex and the level of haemolytic activity.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1744-313X.1978.tb00631.x
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