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  • 101
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    Avoided object Another matter (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 917-917 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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    URL: http://dx.doi.org/10.1038/40027
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  • 102
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    Palaeontology Deep roots for the Neanderthals (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 917-918 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Since their bones were first discovered in the last century, the inventory of Neanderthals from Europe has grown substantially. These people are known from caves and rock shelters of the Late Pleistocene (130,000 years ago), and their anatomy has been described in detail. Older fossils that seem to ...
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    URL: http://dx.doi.org/10.1038/40024
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  • 103
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    Cassini mission blasts off for Saturn (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 769-769 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] washington... Cassini, the most ambitious and expensive planetary expedition ever mounted, began its long trip to Saturn from Cape Canaveral, Florida, on 15 October (left). The spacecraft, which is costing the US, European and Italian space agencies $3.3 billion to build, ...
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  • 104
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    Speciation in the open ocean (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 803-804 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Species inhabiting the open oceans generally occupy broad distribution ranges, extending from parts of ocean basins to entire oceans. Such oceanic species are accepted as monospecific because of their tendency to be dispersed across great distances by ocean currents. Indeed, there are few known ...
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  • 105
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    Gabo's geometry (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 919-919 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ... Intuition of the resonances between natural and human structures is as old as the oldest surviving writings on architecture — even older if we take into account Aristotle's fascination with nature's ‘constructivists’, such as the cell-building bee and geometrically ...
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  • 106
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    Mixed blessings for middle-aged mothers (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 922-922 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Perls et al. in Scientific Correspondence present intriguing data suggesting that bearing children in middle age may be a harbinger for extreme longevity. We have reanalysed another study, which does not lead to the same conclusion. Perls et al. report a significant fourfold excess of ...
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    URL: http://dx.doi.org/10.1038/40042
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  • 107
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    Mixed blessings for middle-aged mothers (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 922-922 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] There are several explanations for the evolution of human longevity and senescence, a recent example being the suggestion by Perls et al. of a relationship between longevity in women and the age at which they bore children. Perls et al. showed that women surviving to at least age 100 were four ...
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  • 108
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    Mixed blessings for middle-aged mothers (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 922-922 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In relation to the question of whether ‘middle-aged’ mothers live longer, raised recently in Scientific Correspondence, there are of course many factors that influence longevity. Menopause is not only a reflection of ovarian ageing: it could primarily be a result of hypothalamic ...
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  • 109
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    Thermal contraction (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 923-924 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The Scientific Correspondence by Roy and Agrawal commenting on a News and Views article by Robert Cahn states that their work had not been acknowledged by Cahn or by us. Cahn's article emphasized negative thermal expansion, but the three reviews mentioned by Roy and Agrawal are about low ...
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  • 110
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    Signs of the times (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 135-136 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...My personal collection of comet memorabilia contains broadsheets, or flyers, issued for the appearances of comets Kohoutek and Halley around Christmas 1973 and in March 1986 respectively, and comet Shoemaker-Levy 9's impact with Jupiter in July 1994. The Kohoutek broadsheet asks “What ...
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    URL: http://dx.doi.org/10.1038/36498
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  • 111
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    Chemist as catalyst (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 134-135 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ... Justus von Liebig (1803-73) was one of the most intriguing figures in the history of chemistry, and his personality and career provide ample material for exploring many themes in the history of science. Appointed to a little-known university, he transformed chemistry teaching and created the ...
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  • 112
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    Getting down to business (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 136-136 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ‘Consulting’ is famously identified with someone who steals your watch to tell you the time and, in this era of ‘downsizing’, has become almost synonymous with ‘unemployed’. An exception to both calumnies is the technical consultant, especially the scientist. ...
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  • 113
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    Corrections (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 136-136 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] • Some incorrect star ratings were awarded to The Colours of Lifeby Lionel R. Milgrom in the review in Nature 389, 687; 1997. They should have been “excellent” for range and style, “good” for depth, accuracy and ...
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  • 114
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    Impaired mast cell-dependent natural immunity in complement C3-deficient mice (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 172-175 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The complement system is widely regarded as essential for normal inflammation, not least because of its ability to activate mast cells. However, recent studies have called into question the importance of complement in several examples of mast cell-dependent inflammatory responses. To ...
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  • 115
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    The data day (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 926-926 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Did you know that in 1994 an okapi at Copenhagen Zoo died of an overdose of Wagner? So says Raymond L. Francis, who reports that the delicate animal preferred death to listening to local singers rehearsing Tannhaüser. It thus showed greater discrimination than Francis, who, as the report ...
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  • 116
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    Sun, sea and life (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 808-808 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ... “Terrestrial plants are so much part of the human experience that aquatic photosynthetic organisms are often overlooked,” say the authors. It may be added that the great diversity of pigment composition and physiological properties among aquatic photosynthetic organisms, together ...
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    URL: http://dx.doi.org/10.1038/39794
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  • 117
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    Polymerized colloidal crystal hydrogel films as intelligent chemical sensing materials (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 829-832 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Chemical sensors respond to the presence of a specific analyte in a variety of ways. One of the most convenient is a change in optical properties, and in particular a visually perceptible colour change. Here we report the preparation of a material that changes colour in response to a chemical ...
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  • 118
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    Launch of Lunar Prospector delayed (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 772-772 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] washingtonThe launch of a low-budget US spacecraft mission to map the chemical composition and gravitational field of the Moon and search for evidence of ice has been delayed for the second time. The $63-million Lunar Prospector will now leave Earth no earlier than 5 January, ...
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    URL: http://dx.doi.org/10.1038/39683
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  • 119
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    Diversity project ‘does not merit federal funding’ (1997)
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    Nature 389 (1997), S. 774-774 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] washingtonThe proposed international Human Genome Diversity Project (HGDP) is not yet sufficiently feasible or well-defined to merit support from US government agencies, according to a study by the National Academy of Sciences. The study, by a panel chaired by Jack Schull of ...
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  • 120
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    erratum Axel Kahn (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 776-776 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Contrary to the headline on a news item in last week's Nature (see Nature 389, 656; 1997), the medical geneticist Axel Kahn is not leaving the Cochin Institute of Molecular Genetics in Paris when he takes up his new position as deputy scientific director ...
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  • 121
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    Neuroscience mardi gras (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 889-889 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Neuronavigation system From Laser Lines A system that will enable surgeons to improve the accuracy and safety of complex operations Near-infrared cameras show surgeons the exact positions of surgical ...
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    URL: http://dx.doi.org/10.1038/39938
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  • 122
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    Canada ‘still has a long way to go’ in effective control of acid rain (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 6-6 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] montreal... Large areas of North America will have to cut sulphur dioxide emissions by an additional three-quarters if they are to control acid rain — a problem many believed to be a thing of the past. A report published last month by the Acidifying Emissions Task Group, ...
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  • 123
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    Space science projects may be grounded (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 8-8 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] munichLeading European space scientists warned last week that Horizons 2000, the long-term science programme of the European Space Agency (ESA), could disintegrate unless a cap on its budget imposed by European governments two years ago is lifted in 1999. The warning has come ...
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  • 124
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    Severe chemical ozone loss in the Arctic during the winter of 1995–96 (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 709-712 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Severe stratospheric ozone depletion is the result of perturbations of chlorine chemistry owing to the presence of polar stratospheric clouds (PSCs) during periods of limited exchange of air between the polar vortex and midlatitudes and partial exposure of the vortex to sunlight. These ...
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  • 125
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    Severe neuropathies in mice with targeted mutations in the ErbB3 receptor (1997)
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    Nature 389 (1997), S. 725-730 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Neuregulins and their specific receptors, members of the ErbB family of tyrosine kinases, have been implicated in the control of growth and development of Schwann cells, specialized cells that wrap around nerve axons to provide electrical insulation. Here we use gene targeting to generate mice ...
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  • 126
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    Chaperoning extended life (1997)
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    Nature 390 (1997), S. 30-30 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The capacity to moderate internal and external stress is arguably the central function regulating senescence in whole-animal ageing. During ageing, molecular chaperones such as heat-shock proteins are thought to combat stress-related senescent dysfunction. In transgenic Drosophila melanogaster, ...
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  • 127
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    A bluffer's guide (1997)
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    Nature 390 (1997), S. 35-36 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In 1847, the aged Dr Routh, president of Magdalen and one of the foremost scholars of his day, was asked what precept he could offer to guide and sustain a young man embarking on a life of learning. After long thought, his face brightened and he spoke thus: “I think, sir, since you care for ...
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  • 128
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    Inner visions (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 41-41 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ... How do we come into being? Few questions are as fundamental, or as appealing to the imagination, as this one. The process by which we are shaped into existence is a phenomenon at once commonplace and portentous. Millions are conceived and millions born every day, following an unvarying plan. ...
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  • 129
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    O brave new world that has Prozac in't! (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 390 (1997), S. 44-44 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ... Two subtitles maketh a reviewer's job easier. And should one miss the quasi-eighteenth-century prolixity of the title page, the opening lines also summarize the argument: “The premise of this book is that we are unhappier compared with 1950⃛ that people who are unhappy tend to have ...
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  • 130
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    The capsaicin receptor: a heat-activated ion channel in the pain pathway (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 816-824 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Capsaicin, the main pungent ingredient in ‘hot’ chilli peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. We have used an expression cloning strategy based on calcium influx ...
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  • 131
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    Ambient acoustic imaging in helioseismology (1997)
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    Nature 389 (1997), S. 825-827 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The increasing availability of high spatial resolution data of velocity and intensity variations on the Sun has stimulated the development of helioseismological techniques that probe the solar interior in localized regions. The techniques developed so far have yielded information on physical ...
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  • 132
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    Prolonged stratospheric ozone loss in the 1995–96 Arctic winter (1997)
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    Nature 389 (1997), S. 835-838 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] It is well established that extensive depletion of ozone, initiated by heterogenous reactions on polar stratospheric clouds (PSCs) can occur in both the Arctic and Antarctic lower stratosphere. Moreover, it has been shown that ozone loss rates in the Arctic region in recent years reached values ...
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    DNA fingerprinting from single cells (1997)
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    Nature 389 (1997), S. 555-556 
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    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Van Oorschot and Jones reported in Scientific Correspondence that short tandem repeat (STR) profiles (DNA fingerprints) can be obtained from cells left on pens, car keys, and so on. Although this technique is a dramatic breakthrough with important implications for forensic science, there are ...
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    Inquiry investigates ‘hiding’ of unspent funds (1997)
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    Nature 389 (1997), S. 897-897 
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    Notes: [Auszug] tokyoFive research-related faculties and four research institutes at Kyoto University are under investigation for allegedly ‘hiding’ unspent research funds. Such funds should have been returned to the government at the end of the fiscal year. The Ministry of ...
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    New in paperback (1997)
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    Nature 389 (1997), S. 560-560 
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    Induced long-range order in crosslinked ‘one-dimensional’ stacks of fluid monolayers (1997)
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    Nature 389 (1997), S. 576-579 
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    Notes: [Auszug] Ordinary crystals are characterized by long-range translational order in all three dimensions. In lower-dimensional systems, in contrast, translational order is destroyed through the ‘Landau–Peierls instability’ — displacements from periodic ordering due to thermal ...
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    Convergent total synthesis of a tumour-associated mucin motif (1997)
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    Nature 389 (1997), S. 587-591 
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    Notes: [Auszug] Synthetic glycoconjugates that mimic cell-surface tumour antigens (glycolipids or glycoproteins with unusual carbohydrate structural motifs) have been shown to trigger humoral responses in murine and human immune systems. This raises the exciting possibility of inducing active immunity with ...
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    Brazil to sequence ‘first plant pathogen’ (1997)
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    Nature 389 (1997), S. 654-654 
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    Notes: [Auszug] são pauloThe creation of a network of laboratories in São Paulo state, Brazil, to sequence the complete genome of a microorganism was announced last week by the Foundation for the Support of Research of the State of São Paulo (FAPESP), the state funding ...
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    Telomerase Cancer and the knockout mouse (1997)
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    Nature 389 (1997), S. 551-552 
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    Notes: [Auszug] Telomeres are specialized structures at the ends of linear chromosomes. They usually consist of tandem arrays of a short DNA sequence (TTAGGG in vertebrates) and associated proteins, and they are thought to have at least two essential functions. First, they stop natural chromosome ends behaving as ...
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    Systemic signalling in gene silencing (1997)
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    Nature 389 (1997), S. 553-553 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Gene silencing in plants is a genetic control mechanism implicated in virus resistance,, genome maintenance and developmental control. We describe here our recent discovery that there is a systemic signal that can mediate gene silencing. From the gene-specificity of the systemic silencing, we ...
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    The lateral line can mediate rheotaxis in fish (1997)
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    Nature 389 (1997), S. 960-963 
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    Notes: [Auszug] Rheotaxis is a behavioural orientation to water currents. It has been demonstrated physiologically that some lateral-line receptors are particularly well suited to provide information on water currents, but their contribution to rheotaxis has been largely overlooked. The accepted view is that ...
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    Seismologists claim quake data being ‘mis-read’ as bomb test (1997)
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    Nature 389 (1997), S. 425-425 
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    Notes: [Auszug] washington... Publicly accessible data clearly show that a seismic event in northern Russia, which has been interpreted as a possible secret nuclear weapons test, was in fact a small earthquake, according to prominent US seismologists. But they are angry that their assessment ...
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    Origin of rubber-like behaviour in metal alloys (1997)
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    Nature 389 (1997), S. 579-582 
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    Notes: [Auszug] Since 1932 it has been known that a number of ordered alloys show an unusual kind of deformation behaviour. These alloys (including Au–Cd, Au–Cu–Zn, Cu–Zn–Al, Cu–Al–Ni), after being aged for some time in a martensitic state (the low-symmetry phase of a ...
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    How the brain learns to see objects and faces in an impoverished context (1997)
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    Nature 389 (1997), S. 596-599 
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    Notes: [Auszug] A degraded image of an object or face, which appearsmeaningless when seen for the first time, is easily recognizableafter viewing an undegraded version of the same image. The neural mechanisms by whichthis form of rapid perceptual learning facilitates perception are notwell understood. ...
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    An epithelial serine protease activates the amiloride-sensitive sodium channel (1997)
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    Nature 389 (1997), S. 607-610 
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    Notes: [Auszug] Sodium balance, and ultimately blood pressure and extracellular fluid volume, is maintained by precise regulation of the activity of the epithelial sodium channel (ENaC). In a Xenopus kidney epithelial cell line (A6), exposure of the apical membrane to theprotease inhibitor aprotinin reduces ...
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    Smad6 inhibits signalling by the TGF-β superfamily (1997)
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    Nature 389 (1997), S. 622-626 
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    Notes: [Auszug] SMAD proteins have been identified as signalling mediators of the TGF-β superfamily, which is involved in a range of biological activities including cell growth, morphogenesis, development and immune responses,. Smad1, Smad2, Smad3 and Smad5 are ligand-specific: Smad1 and Smad5 transduce ...
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    Tools for biomedical research labs (1997)
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    Nature 389 (1997), S. 644-646 
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    Notes: [Auszug] LabCD From Gamera Bioscience While this product still has to undergo beta testing during the next year, the concept is interesting enough for a preview of what should be available in 1999 Based on disposable ...
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    Mitotic chromatin regulates phosphorylation of Stathmin/Op18 (1997)
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    Nature 389 (1997), S. 640-643 
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    Notes: [Auszug] Meiotic and mitotic spindles are required for the even segregation of duplicated chromosomes to the two daughter cells. The mechanism of spindle assembly is not fully understood, but two have been proposed that are not mutually exclusive. The ‘search and capture’ model suggests ...
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    Not the last word on the BSE crisis (1997)
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    Nature 389 (1997), S. 423-423 
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    Notes: [Auszug] If politics was an exact science, then the two papers published in this week's issue on the relationship between bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans might be read as the final chapter — if not the postscript — in an unhappy saga ...
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    US dispute over live AIDS vaccine trials (1997)
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    Nature 389 (1997), S. 426-426 
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    Notes: [Auszug] washingtonThe leaders of a group of 50 volunteers who argue that the time is ripe for human trials of an AIDS vaccine containing live HIV claim that the US National Institutes of Health (NIH) are dragging its feet over support for such work. But NIH leaders and other leading ...
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    Serrate2 is disrupted in the mouse limb-development mutant syndactylism (1997)
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    Nature 389 (1997), S. 722-725 
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    Notes: [Auszug] The mouse syndactylism ( sm ) mutation impairs some of the earliest aspects of limb development and leads to subsequent abnormalities in digit formation. In sm homozygotes, the apical ectodermal ridge (AER) is hyperplastic by embryonic day 10.5, leading to abnormal dorsoventral thickening of ...
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    Sex on the brain (1997)
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    Nature 389 (1997), S. 801-801 
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    Notes: [Auszug] Reports of morphological differences between the brains of humans with different sexual orientation or gender identity have furthered speculation that such behaviours may result from hormonal or genetic influences on the developing brain. However, the causal chain may be reversed; sexual ...
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    Extraterrestrial handedness (1997)
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    Nature 389 (1997), S. 804-804 
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    Notes: [Auszug] M. H. Engel and S. A. Macko tentatively ascribe the enantiomeric excess of L-amino acids in extraterrestrial sources to the circular polarization of synchrotron radiation, from a neutron star, incident on the interstellar molecular cloud from which the Solar System formed (see also the ...
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    Body language (1997)
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    Nature 389 (1997), S. 806-806 
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    Dangerous liaisons (1997)
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    Nature 389 (1997), S. 807-808 
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    Notes: [Auszug] This is the third novel in a series of what the chemist Carl Djerassi calls “science-infiction” in which everything mentioned could or does exist. “Most of my characters, fictional as well as real, are scientists,” he says. “By exposing their lives, I try to make ...
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    Nobel panel rewards prion theory after years of heated debate (1997)
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    Nature 389 (1997), S. 529-529 
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    Notes: [Auszug] london... The 1997 Nobel Prize in Physiology and Medicine was awarded this week to Stanley Prusiner of the University of California, San Francisco, for his contributions towards the identification of the infectious agent that causes transmissible spongiform encephalopathies ...
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    Surveyor maps desert valleys of Mars (1997)
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    Nature 389 (1997), S. 530-530 
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    Notes: [Auszug] london... Preliminary images sent back by the orbiting Mars Global Surveyor show a desert-like terrain pock-marked with craters. The mapped region (above) is called Nirgal Vallis, which is one of a number of canyons known as valley networks. The origin of these valleys is the ...
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    Plagiarism claims turn spotlight on US Navy's misconduct policy (1997)
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    Nature 389 (1997), S. 532-532 
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    Notes: [Auszug] san diegoA psychologist alleged to have plagiarized at least three books has been picked to head the research office at a major US Navy facility. The appointment raises questions about how the Navy deals with cases of scientific misconduct. Dennis L. Reeves, who is 46, was ...
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    The exocytotic event in chromaffin cells revealed by patch amperometry (1997)
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    Nature 389 (1997), S. 509-512 
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    Notes: [Auszug] In mast cells and granulocytes, exocytosis starts with the formation of a fusion pore,,. It has been suggested that neurotransmitters may be released through such a narrow pore without full fusion,. However, owing to the small size of the secretory vesicles containing neurotransmitter, the ...
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    Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours (1997)
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    Nature 389 (1997), S. 876-881 
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    Notes: [Auszug] Sporadic basal cell carcinoma (BCC) is the most common type of malignant cancer in fair-skinned adults. Familial BCCs and a fraction of sporadic BCCs have lost the function of Patched (Ptc), a Sonic hedgehog (Shh) receptor that acts negatively on this signalling pathway. Overexpression of Shh ...
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    Trust and the bioethics industry (1997)
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    Nature 389 (1997), S. 647-647 
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    Notes: [Auszug] There has been something both reassuring and disturbing about the conviction with which the leaders of virtually every advanced industrialized nation have taken a strong public stance against the cloning of human beings, reflected most recently in last weekend's statement from the summit meeting of ...
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    US energy official departs with a ‘get real’ warning (1997)
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    Nature 389 (1997), S. 650-650 
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    Notes: [Auszug] washington... The senior official responsible for environment, health and safety at the US Department of Energy leaves Washington this week with a warning for scientists: engage with the communities you live in, or face oblivion. Tara O'Toole, a physician who has spent four ...
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    Russia warned: act now or regret it later (1997)
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    Nature 389 (1997), S. 659-659 
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    Notes: [Auszug] If the Russian government fails to introduce legislation on genetic engineering soon, “in two or three years it will be too late — the state will not be able to control the safety of newly produced food and medicines”. That was the warning given last month by Rem Petrov, the ...
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    Creationist appeal told that Ark claims ‘were scientific’ (1997)
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    Nature 389 (1997), S. 323-323 
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    Notes: [Auszug] sydneyA Sydney court was told last week that public lectures by Bible church elder Allen Roberts on his claims that he had found evidence for the existence of Noah's Ark in Turkey were scientific, not religious, in character, and should be judged as such. David Bennett QC was ...
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    UK takes pride in ‘principled pragmatism’ (1997)
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    Nature 389 (1997), S. 663-663 
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    Notes: [Auszug] Early last year, the British government announced that it had decided not to follow the advice of a committee of the House of Commons to set up a panel to monitor the social impact of human genetics research, arguing that this would create unnecessary bureaucracy (see Nature ...
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    Artificial enzymes The importance of being selective (1997)
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    Nature 389 (1997), S. 329-330 
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    Notes: [Auszug] Hydroxylating enzymes introduce one or more O-H groups into organic compounds and are involved in many biological processes. But how do they work? And how might these systems be redesigned to practical ends? Bioorganic chemists address these questions by using synthetic molecular systems. A ...
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    Particle physics Panning for gold at the K stream (1997)
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    Nature 389 (1997), S. 671-673 
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    Notes: [Auszug] In 1947, while studying cloud-chamber pictures of cosmic-ray showers, Rochester and Butler found two pictures, among 50 exposures, that seemed to represent the decay of two unstable particles. The tracks were quite different from anything seen before, and were not anticipated by any theory. The ...
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    Alzheimer's disease The ins and outs of amyloid- β (1997)
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    Nature 389 (1997), S. 677-678 
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    Notes: [Auszug] The devastating consequences of Alzheimer's disease — marked by extracellular senile plaques with fibrils of amyloid-β peptide (Aβ) and intraneuronal tangles of polymerized tau protein — are experienced by more and more elderly people in the Western world. The latest step ...
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    Allosteric proteins Cuddling up to channel activation (1997)
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    Nature 389 (1997), S. 328-329 
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    Notes: [Auszug] Proteins are intelligent beings. They have evolved to operate in the metabolic maelstrom of a turbulent cellular environment. Transcription factors must know when to switch genes on or off, and the cellular levels of specific ‘signalling’ molecules — lactose, retinoic acid, ...
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    At a glance (1997)
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    Nature 389 (1997), S. 687-687 
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    Notes: [Auszug] Isotopic methods today crop up in every branch of modern Earth sciences and can elucidate countless processes that have shaped the Earth throughout its history, as well as making possible the dating of geological events. Here is a conscientious attempt to summarize the general principles of ...
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    A single-electron transistor made from a cadmium selenide nanocrystal (1997)
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    Nature 389 (1997), S. 699-701 
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    Notes: [Auszug] The techniques of colloidal chemistry permit the routine creation of semiconductor nanocrystals, whose dimensions are much smaller than those that can be realized using lithographic techniques. The sizes of such nanocrystals can be varied systematically to study quantum size effects or to make ...
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    A synthetic peptide ligase (1997)
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    Nature 389 (1997), S. 706-709 
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    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The preparation of synthetic molecules showing the remarkable efficiencies characteristic of natural biopolymer catalysts remains a formidable challenge for chemical biology. Although significant advances have been made in the understanding of protein structure and function, the de novo ...
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    Radical alterations in the roles of homeobox genes during echinoderm evolution (1997)
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    Nature 389 (1997), S. 718-721 
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    Notes: [Auszug] Echinoderms possess one of the most highly derived body architectures of all metazoan phyla, with radial symmetry, a calcitic endoskeleton, and a water vascular system,. How these dramatic morphological changes evolved has been the subject of extensive speculation and debate, but remains ...
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    Neuronal position in the developing brain is regulated by mouse disabled-1 (1997)
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    Nature 389 (1997), S. 733-737 
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    Notes: [Auszug] During mammalian brain development, immature neurons migrate radially from the neuroectoderm to defined locations, giving rise to characteristic cell layers,. Here we show that targeted disruption of the mouse disabled1 ( mdab1 ) gene disturbs neuronal layering in the cerebral cortex, ...
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    ‘Policy vacuum’ worry as Australian minister quits (1997)
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    Nature 389 (1997), S. 427-427 
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    Notes: [Auszug] adelaide... Australia's Coalition government, led by prime minister John Howard of the Liberal party, has been plunged into crisis following the forced resignation last Friday (26 September) of Peter McGauran, Minister for Science and Technology, in the wake of the departure of ...
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    ‘Government should decide on disposal site’ (1997)
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    Nature 389 (1997), S. 428-428 
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    Notes: [Auszug] londonNirex, Britain's nuclear waste disposal agency, has made clear that it does not want responsibility for choosing a new waste-disposal site — even if the government decides that it should retain its independence. According to John Holmes, Nirex's director of ...
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    Academy focuses on bringing laser into use (1997)
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    Nature 389 (1997), S. 430-430 
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    Notes: [Auszug] pragueThe iodide laser was sold to the Czech Academy of Sciences last spring by the Max Planck Institute for Quantum Optics in Garching, near Munich, for a token cost of DM1 (US$0.56). It was one of a series of Asterix lasers developed in Garching and optimized for laser and ...
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    Cloning and bioethical thinking (1997)
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    Nature 389 (1997), S. 433-433 
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    Notes: [Auszug] SirAxel Kahn reminds us, rightly, that Kant's famous principle states: “Respect for human dignity requires that an individual is never used⃛ exclusively as a means”, and suggests that I have ignored the crucial use of the term ‘exclusively’ ...
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    European centres for disease control (1997)
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    Nature 389 (1997), S. 433-433 
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    Notes: [Auszug] SirThe US Centers for Disease Control (CDC), in Atlanta, Georgia, are a federal organization with two missions: disease control and research. Its size (several thousand people) and centralized concept make it a powerful tool for addressing the challenge of emerging and ...
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    Human BSE (1997)
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    Nature 389 (1997), S. 437-438 
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    Notes: [Auszug] On 20 March 1996 the UK government announced that a distinct variant of Creutzfeldt-Jakob disease (vCJD) had occurred in ten people in the United Kingdom over the previous 14 months. Like CJD, the variant form results in brain damage and death; but it is pathologically and ...
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    Evolutionary biology Pelvic problems for mammals (1997)
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    Nature 389 (1997), S. 440-441 
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    Notes: [Auszug] Living mammals can be subdivided into the monotremes (which lay eggs), the marsupials (which nurture their young in a pouch) and the placentals (in which the young stay in the uterus until a comparatively late stage of development). Traditionally, the epipubis or so-called ‘marsupial ...
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    100 and 50 years ago (1997)
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    Nature 389 (1997), S. 444-444 
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    Notes: [Auszug] 100 years ago It is much to be regretted that the splendid male Giraffe, presented to the Queen by the Chief Bethoen, of Bechuanaland, died so soon after reaching this country. It was placed on board the s.s. Roslin Castle ⃛ and left Cape Town on September 1. The ...
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    Porous silica via colloidal crystallization (1997)
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    Nature 389 (1997), S. 447-448 
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    Notes: [Auszug] Microstructured porous silicas have potential applications in catalysis, separations, coatings, microelectronics and electro-optics, but methods for producing materials with uniform submicrometre pores have not been available. We have now developed a method in which modified colloidal crystals ...
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    Return of the repressed (1997)
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    Nature 389 (1997), S. 451-452 
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    Notes: [Auszug] ... Scepticism has a long history of dethroning disciplines that try to monopolize truth. It knocked religion from its pedestal, and then went on to undo philosophy. Now its chief target is science. These two books are the latest in a long line of onslaughts on the claimed integrity and truth of ...
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    ‘Surprising success’ of the Montreal Protocol (1997)
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    Nature 389 (1997), S. 219-219 
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    Notes: [Auszug] montrealOne of the first scientists to have pointed out in the mid-1970s the potential threat to the atmosphere of CFCs said last week that he had been both surprised and impressed by the success of the Montreal Protocol in restricting their emissions. “It was ...
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    C. P. Snow's ‘two cultures’ thesis was just ‘declinist whinging’ (1997)
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    Nature 389 (1997), S. 221-221 
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    Notes: [Auszug] leeds, englandClaims by the late British novelist C. P. Snow that a ‘two cultures’ gap separates those who have studied the humanities from those who have studied the sciences came under spirited attack last week from a historian of science for misrepresenting the ...
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    Cheques and balances (1997)
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    Nature 389 (1997), S. 224-224 
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    Notes: [Auszug] SirHermann Bondi rightly remarks that there must be an optimum balance or ratio (albeit subject-dependent) between the expenditure on scientists and that on their equipment, and points out that the current ratio is too high because of the widespread obsolescence of equipment ...
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    Apoptosis Clues in the p53 murder mystery (1997)
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    Nature 389 (1997), S. 237-238 
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    Notes: [Auszug] The paper by Polyak et al. on page 300 of this issue is a bold step towards understanding why expression of the oncosuppressor protein p53 leads to cell death. The issue is important because p53 forms part of a ‘fast-track’ connection between nuclear DNA damage and the complex ...
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    Reptile relationships turn turtle⃛ (1997)
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    Nature 389 (1997), S. 245-245 
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    Notes: [Auszug] Turtles are so anatomically bizarre that their affinities with other reptiles remain contentious. Wilkinson et al. showed how even the extensive morphological information amassed by Rieppel and deBraga provides only weak support for their view that turtles are advanced diapsid reptiles, rather ...
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    Daughters against dpp modulates dpp organizing activity in Drosophila wing development (1997)
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    Nature 389 (1997), S. 627-631 
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    Notes: [Auszug] The family of TGF-β signalling molecules play inductive roles in various developmental contexts. One member of this family, Drosophila Decapentaplegic (Dpp) serves as a morphogen that patterns both the embryo, and adult,. We have now isolated a gene, Daughters against dpp ( Dad), whose ...
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    Direct stimulation of Bruton's tyrosine kinase by G q -protein α-subunit (1997)
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    Nature 389 (1997), S. 296-299 
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    Notes: [Auszug] Heterotrimeric guanine-nucleotide-binding regulatory proteins (G proteins) transduce signals from a wide variety of cell-surface receptors to generate physiological responses. Protein-tyrosine kinases are another group of critical cellular signal transducers and their malfunction often leads to ...
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    Solvents Molecular trees for green chemistry (1997)
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    Nature 389 (1997), S. 333-334 
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    Notes: [Auszug] Because carbon dioxide is nontoxic, nonflammable, abundant and cheap, it ought to be every scientist's and engineer's favourite solvent for extractions, separations and reactions. Unfortunately, even at dense liquid or supercritical conditions, its ability to dissolve polymeric, ionic or highly ...
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    Santa Fe centre seeks second wind (1997)
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    Nature 389 (1997), S. 106-107 
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    Notes: [Auszug] santa fe... The Santa Fe Institute (SFI) in New Mexico was set up to escape from US funding restrictions, turf wars, internal division and isolation from the outside world. Those were among the factors that drove a small cadre of talented physicists from the Los Alamos National ...
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    Bidder for Brookhaven centre bails out (1997)
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    Nature 389 (1997), S. 110-111 
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    Notes: [Auszug] washington... One of two consortia bidding to manage the troubled Brookhaven National Laboratory on Long Island, New York, withdrew its bid this week, leaving the Department of Energy (DoE) struggling to convince Congress that the contract will still be properly contested. The ...
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    Western research assessment meets Asian cultures (1997)
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    Nature 389 (1997), S. 113-117 
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    Notes: [Auszug] The emerging economies of the Pacific Rim of Asia are applying research assessment to boost the quantity and quality of their research, while Japan is just awakening to the need for such processes. But cultural obstacles have led to diverse approaches across the region.... Around the ...
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    Self-organization of microtubules and motors (1997)
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    Nature 389 (1997), S. 305-308 
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    Notes: [Auszug] Cellular structures are established and maintained through a dynamic interplay between assembly and regulatory processes. Self-organization of molecular components provides a variety of possible spatial structures: the regulatory machinery chooses the most appropriate to express a given ...
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    Accidents prompt Los Alamos closure (1997)
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    Nature 389 (1997), S. 105-105 
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    Notes: [Auszug] san franciscoThe US Los Alamos National Laboratory in New Mexico is to shut down a nuclear weapons research facility for six months following a spate of accidents. A $175-million refurbishment will be carried out during the shutdown. The Chemistry and Metallurgy Research ...
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    Gene therapist accused of fraud to seek redress in German court (1997)
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    Nature 389 (1997), S. 105-105 
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    Notes: [Auszug] munich ... Germany's most notable case of alleged scientific fraud took a new turn last week with the announcement that one of the two accused scientists intends to sue investigators in the case for DM10 million (US$5.6 million), in compensation for damage to his career. ...
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    Respite for NASA's troubled data system (1997)
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    Nature 389 (1997), S. 108-108 
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    Notes: [Auszug] washington... The US National Aeronautics and Space Administration (NASA) was this week optimistic that its troubled computer system for handling vast amounts of data from a planned constellation of Earth-observation satellites will be up and running for the scheduled launch of ...
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    Earth scientists count the cost of loss of Lewis demo satellite (1997)
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    Nature 389 (1997), S. 108-108 
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    Notes: [Auszug] washingtonHope is fading that US ground controllers will be able to regain control of the $71-million Lewis demonstration satellite before it re-enters the Earth's atmosphere around mid-September. The satellite, which is testing the feasibility of hyperspectral imagery of ...
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