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  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 38 (1997), S. 342-347 
    ISSN: 0021-9304
    Keywords: phosphorus ; ion implantation ; silica glass ; radiotherapy ; chemical durability ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A chemically durable glass containing a large amount of phosphorus is useful for in situ irradiation of cancers. It can be activated to be a β emitter (half-life of 14.3 days) by neutron bombardment. Microspheres of the activated glass injected into the tumors can irradiate the tumors directly with β rays without irradiating neighboring normal tissues. In the present study a P+ ion was implanted into a pure silica glass in a plate form at 100 keV in order to find the fundamental conditions for obtaining such a glass. Little phosphorus was present in the surface region, at least to a depth of 2.4 nm for doses of 5 × 1016 and 1 × 1017 cm-2, whereas an appreciable amount of it was distributed on the glass surface and a part of it was oxidized for doses above 5 × 1017 cm-2. The glasses implanted with doses of 5 × 1016 and 1 × 1017 cm-2 hardly released the P and Si into water at 95 °C, even after 7 days, whereas the glasses implanted with doses above 5 × 1017 cm-2 released appreciable amounts of these elements. Implantation energies of 20 and 50 keV (even at doses of 5 × 1016 and 1 × 1017 cm-2, respectively), formed oxidized phosphorus on the glass surfaces and gave appreciable releases of the P and Si into the hot water. This indicates that a chemically durable glass containing a larger amount of phosphorus could be obtained if a P+ ion is implanted at higher energies to localize in a deeper region of the glass surface. © 1997 John Wiley & Sons, Inc. J Biomed Mater Res (Appl Biomater) 38: 342-347, 1997
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-2983
    Keywords: Zinc ; copper ; manganese ; iron ; lead ; cadmium ; nickel ; phosphorus ; limestone ; fertilizer ; sewage sludge compost
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Medicine
    Notes: Abstract Previous research has demonstrated that many urban soils are enriched in Pb, Cd and Zn. Culture of vegetable crops in these soils could allow transfer of potentially toxic metals to foods. ‘Tanya’ lettuce (Lactuca sativa L.) was grown in pots of five urban garden soils and one control agricultural soil to assess the effect of urban-soil metal enrichment, and the effect of soil amendments, on heavy metal uptake by garden vegetables. The amendments included NPK fertilizer, limestone, Ca(H2PO4)2, and two rates of limed sewage sludge compost. Soil Cd ranged from 0.08 to 9.6 mg kg−1; soil Zn from 38 to 3490 mg kg−1; and soil Pb from 12 to 5210 mg kg−1. Lettuce yield on the urban garden soils was as great as or greater than that on the control soil. Lettuce Cd, Zn and Pb concentrations increased from 0.65, 23, and 2.2 mg kg−1 dry matter in the control soil to as high as 3.53, 422 and 37.0 mg kg−1 on the metal-rich urban garden soils. Adding limestone or limed sewage sludge compost raised soil pH and significantly reduced lettuce Cd and Zn, while phosphate fertilizer lowered soil pH and had little effect on Zn but increased Cd concentration in lettuce. Urban garden soils caused a significant increase in lettuce leaf Pb concentration, especially on the highest Pb soil. Adding NPK fertilizer, phosphate, or sludge compost to two high Pb soils lowered lettuce Pb concentration, but adding limestone generally did not. On normally fertilized soils, Pb uptake by lettuce was not exceptionally high until soil Pb substantially exceeded 500 mg kg−1. Comparing garden vegetables and soil as potential sources of Pb risk to children, it is clear that the risk is greater through ingestion of soil or dust than through ingestion of garden vegetables grown on the soil. Urban dwellers should obtain soil metal analyses before selecting garden locations to reduce Pb risk to their children.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Magnetic resonance materials in physics, biology and medicine 1 (1993), S. 65-76 
    ISSN: 1352-8661
    Keywords: nuclear magnetic resonance spectroscopy ; phosphorus ; brain ; curve fitting ; NMR1™
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics
    Notes: Abstract A procedure is presented for the computerized automated curve fitting ofin vivo 31P NMR data. This procedure was implemented in the form of three C shell scripts (Appendix) which automatically execute commands from the commercial software program, NMR1™. The accuracy and limitations of curve fitting was tested using simulated data designed to representin vivo 31P NMR spectra obtained from brain. For isolated peaks, the predicted areas for 140 test spectra were in good agreement with the noise free or ‘true’ values, with variations on the order of that expected for the calculated S/N of the simulated peaks. However, when the S/N was less than 2:1, predicted areas were systemically overestimated; this error was traced to a bias for linewidth overestimates. For peaks that overlap, a second systematic error was noted in predicted areas for adjacent peaks, where one peak area was overestimated and the other was underestimated. Furthermore, these systematic errors show partial inverse co-linearity with each other, increasing in proportion to the extent of peak overlap. The curve fitting procedure and tests described here provide guidelines and cautions to investigators who endeavour to use computerized procedures for the analysis ofin vivo NMR spectroscopic data using NMR1 or other software programs.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of experimental biology and medicine 101 (1986), S. 135-138 
    ISSN: 1573-8221
    Keywords: phosphorus ; oral mucosa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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