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  • United States  (110)
  • Base Sequence
  • Cell & Developmental Biology
  • Engineering
  • SPACE SCIENCES
  • American Association for the Advancement of Science (AAAS)  (135)
  • Santa Barbara, CA
  • 1975-1979  (135)
Collection
Keywords
Publisher
Years
Year
  • 1
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    New strength in the diet-disease link? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Nov 9;206(4419):666-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493971" target="_blank"〉PubMed〈/a〉
    Keywords: Diet/*adverse effects ; Disease/*etiology ; Humans ; Legislation as Topic ; National Institutes of Health (U.S.) ; Nutritional Physiological Phenomena ; Peer Review ; Preventive Medicine/methods ; Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    NIH deals gingerly with diet-disease link (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1175-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451563" target="_blank"〉PubMed〈/a〉
    Keywords: Diabetes Mellitus/etiology ; Diet/*adverse effects ; Disease/*etiology ; *National Institutes of Health (U.S.) ; Neoplasms/etiology ; *Nutritional Physiological Phenomena ; Preventive Medicine ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Approval sought for nerve gas pilot plant (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Dec 7;206(4423):1164, 1166.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/504999" target="_blank"〉PubMed〈/a〉
    Keywords: *Chemical Warfare Agents ; Containment of Biohazards ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Dispute over cancer risk quantification (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Mar 30;203(4387):1324-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/106470" target="_blank"〉PubMed〈/a〉
    Keywords: Benzene/*toxicity ; *Carcinogens ; Cost-Benefit Analysis ; Environmental Exposure ; Government Agencies ; Legislation, Drug ; Risk ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Regulation of gene expression: possible role of repetitive sequences (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: Large contrasts are observed between the messenger RNA populations of different tissues and of embryos at different stages of development. Nevertheless, coding sequences for genes not expressed in a cell appear to be present in its nuclear RNA. Though many nuclear RNA transcripts of single copy DNA sequences are held in common between tissues, an additional set, probably consisting of non-message sequences, is not shared. Nuclear RNA also contains transcripts of repetitive DNA sequences. Certain repeat families are represented at high levels in the nuclear RNA of particular tissues and much lower levels in others. It is surprising that both complements of most repeat sequences are present in nuclear RNA. These observations lead to model for regulation of gene expression in which the formation of repetitive RNA-RNA duplexes controls the production of messenger RNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Davidson, E H -- Britten, R J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1052-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451548" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cell Nucleus/physiology ; DNA/*genetics ; Genes ; *Genes, Regulator ; Hydrogen Bonding ; Mammals/embryology ; Models, Biological ; Polyribosomes/metabolism ; *RNA, Heterogeneous Nuclear/genetics ; RNA, Messenger/genetics ; Sea Urchins/embryology ; *Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Viroids: structure and function (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-31
    Description: Viroids are nucleic acid species of relatively low molecular weight and unique structure that cause several important diseases of cultivated plants. Similar nucleic acid species may be responsible for certain diseases of animals and humans. Viroids are the smallest known agents of infectious disease. Unlike viral nucleic acids, viroids are not encapsidated. Despite their small size, viroids replicate autonomously in cells of susceptible plant species. Known viroids are single-stranded, covalently closed circular, as well as linear, RNA molecules with extensive regions of intramolecular complementarity; they exist in their native state as highly base-paired rods.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Diener, T O -- New York, N.Y. -- Science. 1979 Aug 31;205(4409):859-66.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472709" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; DNA, Viral/genetics ; Molecular Weight ; Nucleic Acid Conformation ; Plant Viruses/*genetics/isolation & purification/ultrastructure ; RNA, Viral/*genetics ; Templates, Genetic ; Virus Replication
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Headache for Bristol-Myers (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1979 Nov 2;206(4418):540-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493959" target="_blank"〉PubMed〈/a〉
    Keywords: Advertising as Topic/standards ; Analgesics/*standards ; Aspirin/*standards ; Drug Industry/*standards ; Jurisprudence ; Nonprescription Drugs/*standards ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Basic research in the United States (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Handler, P -- New York, N.Y. -- Science. 1979 May 4;204(4392):474-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432651" target="_blank"〉PubMed〈/a〉
    Keywords: Astronomy/history ; Biology/history ; Chemistry/history ; Environment ; Government Agencies/history ; History, 20th Century ; Physics/history ; *Research Support as Topic ; Science/*history ; Social Sciences/history ; United States ; Universities/history/manpower
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    Environmental health research (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hiatt, H H -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1361.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505011" target="_blank"〉PubMed〈/a〉
    Keywords: *Environmental Health ; Research ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Total synthesis of a gene (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-16
    Description: The method developed for the total synthesis of a given DNA containing biologically specific sequences consists of the following. The DNA in the double-stranded form is carefully divided into short single-stranded segments with suitable overlaps in the complementary strands. All the segments are chemically synthesized starting with protected nucleosides and mononucleotides. The 5'-OH ends of the appropriate oligonucleotides are then phosphorylated with the use of [y-32P]ATP and polynucleotide kinase. A few to several neighboring oligonucleotides are then allowed to form bihelical complexes in aqueous solution, and the latter are joined end to end by polynucleotide ligase to form covalently linked duplexes. Subsequent heat-to-tail joining of the short duplexes leads to the total DNA. The methods are described for the construction of a biologically functional suppressor transfer RNA gene. The total work involved (i) the synthesis of a 126-nucleotide-long bihelical DNA corresponding to a known precursor to the tyrosine suppressor transfer RNA, (ii) the sequencing of the promoter region and the distal region adjoining the C-C-A end, which contained a signal for the processing of the RNA transcript, (iii) total synthesis of the 207 base-pair-long DNA, which included the control elements, as well as the Eco R1 restriction endonuclease specific sequences at the two ends, and (iv) full characterization by transcription in vitro and amber suppressor activity in vivo of the synthetic gene.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Khorana, H G -- New York, N.Y. -- Science. 1979 Feb 16;203(4381):614-25.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/366749" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; DNA, Recombinant ; DNA-Directed RNA Polymerases/metabolism ; Escherichia coli/genetics ; *Genes ; Genes, Regulator ; Hydrogen Bonding ; Nucleic Acid Conformation ; Oligodeoxyribonucleotides/*chemical synthesis ; Oligonucleotides/*chemical synthesis ; RNA, Transfer/*genetics ; Suppression, Genetic ; Transcription, Genetic ; Tyrosine
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 11
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    Laboratory animal feed (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Knapka, J J -- New York, N.Y. -- Science. 1979 Jun 29;204(4400):1367.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/582217" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed/*analysis ; Animals ; Animals, Laboratory ; Hot Temperature ; National Institutes of Health (U.S.) ; Nitrosamines/analysis ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 12
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    Large drug firms fight generic substitution (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1054-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/493991" target="_blank"〉PubMed〈/a〉
    Keywords: Costs and Cost Analysis ; Drug Industry/*economics ; Legislation, Drug ; *Therapeutic Equivalency ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 13
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    The phenformin ban: is the drug an imminent hazard? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1094-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424735" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Lactates/blood ; Legislation, Drug ; Phenformin/adverse effects/*standards ; United States ; United States Dept. of Health and Human Services ; United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 14
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    New drugs and the brain (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):774-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/379998" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; France ; History, 20th Century ; Humans ; Mice ; Psychotropic Drugs/*history/metabolism/therapeutic use ; Rats ; Schizophrenia/drug therapy ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 15
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    Controversy over study of diabetes drugs continues for nearly a decade (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1979 Mar 9;203(4384):986-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/370980" target="_blank"〉PubMed〈/a〉
    Keywords: Cardiovascular Diseases/chemically induced ; Clinical Trials as Topic ; Diabetes Mellitus/*drug therapy ; Drug Information Services ; History, 20th Century ; Humans ; Hypoglycemic Agents/adverse effects/history/*standards ; Jurisprudence ; Legislation, Drug/*history ; Phenformin/adverse effects ; Research Design/standards ; Tolbutamide/adverse effects ; United States ; United States Food and Drug Administration/history
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 16
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    Panel urges wide use of antiviral drug (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1979 Nov 30;206(4422):1058-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/386515" target="_blank"〉PubMed〈/a〉
    Keywords: Amantadine/history/*therapeutic use ; History, 20th Century ; Humans ; Influenza A virus ; Influenza, Human/prevention & control/*therapy ; National Institutes of Health (U.S.) ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 17
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    NAS study on radiation takes the middle road (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1979 May 18;204(4394):711, 713-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441736" target="_blank"〉PubMed〈/a〉
    Keywords: Congenital Abnormalities/etiology ; Dose-Response Relationship, Radiation ; Humans ; Maximum Allowable Concentration ; Neoplasms, Radiation-Induced/etiology ; Radiation Injuries/*etiology ; Risk ; Societies, Scientific ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 18
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    DNA organization of Methanobacterium thermoautotrophicum (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: The organism Methanobacterium thermoautotrophicum, an archaebacterium, is envolutionarily very distant from both traditional prokaryotes and eukaryotes. Its genome (DNA) has physical characteristics typical of most prokaryotes except that it is quite small (about 10(9) daltons, less than half the size of the genome of Escherichia coli) and contains a significant amount (6 percent) DNA which renatures extremely rapidly.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mitchell, R M -- Loeblich, L A -- Klotz, L C -- Loeblich, A R 3rd -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1082-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/377486" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Biological Evolution ; DNA, Bacterial/*genetics ; Escherichia coli/genetics ; Euryarchaeota/classification/*genetics ; Nucleic Acid Renaturation
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 19
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    NCI bioassays (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shubik, P -- Clayson, D B -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):746, 748.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462187" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Carcinogens ; *Drug Evaluation, Preclinical ; *National Institutes of Health (U.S.) ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 20
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    NCI bioassays yield a trail of blunders (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1287-92.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451534" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biological Assay/methods ; *Carcinogens ; Legislation as Topic ; Mice ; *National Institutes of Health (U.S.) ; Research Design/standards ; Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 21
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    Government-university relations (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-15
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pings, C J -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1158.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451562" target="_blank"〉PubMed〈/a〉
    Keywords: Government Agencies ; *Research Support as Topic ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 22
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    Structure of the constant and 3' untranslated regions of the murine gamma 2b heavy chain messenger RNA (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-14
    Description: The complete coding sequence for the constant region of the mouse gamma 2b immunoglobulin heavy chain and the 3' untranslated region has been determined. The coding portion of the sequence is 1008 nucleotides long (amino acid residues 114 to 449), and the 3' noncoding region contains 102 nucleotides preceeding the polyadenylate. An extra carboxyl-terminal lysine residue which had not been observed in the gamma 2b or other gamma subclass protein sequences occurs in the nucleotide sequence and is probably processed posttranslationally. A 17-nucleotide sequence occurs with slight variation twice in CH1 and once in CH2 domains in the same relative location but with different translational phase. This sequence may be the site of crossover in a gamma 2b . gamma 2a heavy chain variant, an indication of possible recombinational activity of some kind.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tucker, P W -- Marcu, K B -- Slightom, J L -- Blattner, F R -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1299-303.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/117548" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Biological Evolution ; Codon ; DNA, Recombinant ; Immunoglobulin Constant Regions/*genetics ; Immunoglobulin Heavy Chains/*genetics ; Immunoglobulin gamma-Chains/*genetics ; Immunoglobulins/*genetics ; Mice ; *Protein Biosynthesis ; RNA, Messenger/*genetics
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    Surgeon general seeks physicians' help in DES alert (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1979 Jan 12;203(4376):159.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758685" target="_blank"〉PubMed〈/a〉
    Keywords: Diethylstilbestrol/*adverse effects ; Drug Information Services ; Female ; Government Agencies ; Humans ; Mesonephroma/*chemically induced ; United States ; Vaginal Neoplasms/*chemically induced
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    It could have been worse for R & D in Carter's "austerity" budget (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉New York, N.Y. -- Science. 1979 Feb 2;203(4379):416-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760199" target="_blank"〉PubMed〈/a〉
    Keywords: Government ; Research Support as Topic/*economics ; United States
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    Canine Babesia new to North America (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-29
    Description: A domestic dog residing in New England suffered a fatal febrile illness caused by a Babesia infection. The morphology of these intraerythrocytic protozoa and the range of hosts that could be infected experimentally suggested that the parasite was B. gibsoni. Although this tick-bourne disease is enzootic in wild and domestic Canidae in Africa and Asia, it appears to be new to the Americas.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Anderson, J F -- Magnarelli, L A -- Donner, C S -- Spielman, A -- Piesman, J -- New York, N.Y. -- Science. 1979 Jun 29;204(4400):1431-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451574" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Arthropod Vectors ; Babesia/classification/cytology ; Babesiosis/epidemiology/*parasitology/transmission ; Cricetinae ; Dog Diseases/*parasitology ; Dogs ; Erythrocytes/parasitology ; Mice ; United States
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    Jump in funding feeds research on nutrition (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1060-1, 1063-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451549" target="_blank"〉PubMed〈/a〉
    Keywords: *Diet ; Disease ; Government Agencies ; Humans ; Legislation as Topic ; *Nutritional Physiological Phenomena ; Research Support as Topic ; United States ; United States Dept. of Health and Human Services
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    Yearly report on carcinogens could be a potent weapon in the war on cancer (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):525-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760203" target="_blank"〉PubMed〈/a〉
    Keywords: *Carcinogens ; Dose-Response Relationship, Drug ; Government Agencies ; Humans ; Legislation, Drug ; Neoplasms/*prevention & control ; United States
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    Radioactive waste policy is in disarray (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Oct 19;206(4416):312-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482940" target="_blank"〉PubMed〈/a〉
    Keywords: Government Agencies ; Legislation as Topic ; *Radioactive Waste ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 29
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    beta-Galactosidase and selective neutrality (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-09
    Description: Three hypotheses to explain the amino acid composition of proteins are inconsistent (P congruent to 10(-9) with the experimental data for beta-galactosidase from Escherichia coli. The exceptional length of this protein, 1021 residues, permits rigorous tests of these hypotheses without complication from statistical artifacts. Either this protein is not at compositional equilibrium, which is unlikely from knowledge about other proteins, or the evolution of this protein and its coding gene have not been selectively neutral. However, the composition of approximately 60 percent of the molecule is consistent with either a selectively neutral or nonneutral evolutionary process.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holmquist, R -- New York, N.Y. -- Science. 1979 Mar 9;203(4384):1012-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/106468" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Amino Acids/analysis ; Base Sequence ; Biological Evolution ; Escherichia coli/enzymology ; Galactosidases/*genetics ; Genes ; Genetic Code ; *Selection, Genetic ; beta-Galactosidase/analysis/*genetics
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    Public policy and health manpower (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Fordham, C C 3rd -- New York, N.Y. -- Science. 1979 May 4;204(4392):459.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432650" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Medical ; Physicians/*supply & distribution ; *Public Policy ; United States ; United States Dept. of Health and Human Services
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    Toxic waste disposal a growing problem (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Maugh, T H 2nd -- New York, N.Y. -- Science. 1979 May 25;204(4395):819-23.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441738" target="_blank"〉PubMed〈/a〉
    Keywords: Economics ; Environmental Pollutants/*adverse effects ; Government ; Jurisprudence ; Legislation as Topic ; *Refuse Disposal ; *Sewage ; United States ; *Waste Disposal, Fluid
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    Restriction endonucleases, simian virus 40, and the new genetics (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nathans, D -- New York, N.Y. -- Science. 1979 Nov 23;206(4421):903-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/228393" target="_blank"〉PubMed〈/a〉
    Keywords: Antigens, Viral/genetics ; Base Sequence ; Chromosome Mapping ; DNA Replication ; DNA Restriction Enzymes/*metabolism ; DNA, Viral/genetics ; Genes ; Genes, Regulator ; Genetics/*trends ; Nobel Prize ; Simian virus 40/*genetics ; Virus Replication
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    Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-19
    Description: The nucleotide sequence of a cloned rabbit chromosomal DNA segment of 1620 nucleotides length which contains a beta-globin gene is presented. The coding regions are separated into three blocks by two intervening sequences of 126 and 573 base pairs, respectively. The rabbit sequence was compared with a homologous mouse sequence. The segments flanking the rabbit gene, as well as the coding regions, the 5' noncoding and part of the 3' noncoding messenger RNA sequences are similar to those of the mouse gene; the homologous introns, despite identical location, are distinctly dissimilar except for the junction regions. Homologous introns may be derived from common ancestral introns by large insertions and deletions rather than be multiple point mutations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van Ooyen, A -- van den Berg, J -- Mantei, N -- Weissmann, C -- New York, N.Y. -- Science. 1979 Oct 19;206(4416):337-44.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482942" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Biological Evolution ; Codon ; DNA, Recombinant ; Genetic Linkage ; Globins/*genetics ; Mice/*genetics ; Rabbits/*genetics
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    Sequence of the cloned gene for the constant region of murine gamma 2b immunoglobulin heavy chain (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-14
    Description: The complete nucleotide sequence of the gamma 2b constant region gene cloned from BALB/c liver DNA is reported. The sequence of approximately 1870 base pairs includes the 5' flanking, 3' untranslated, and 3' flanking regions and three introns. The C gamma 2b coding region is divided by these introns into four segments corresponding to the homology domains and hinge region of the protein. The introns separating the hinge from the CH2 domain and the CH2 from the CH3 domain are small (106 and 119 base pairs). A larger intervening sequence of 314 base pairs separates the CH1 and hinge regions. The stretch of DNA comprising this large intron plus the hinge shows a strong homology with the other CH domains.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tucker, P W -- Marcu, K B -- Newell, N -- Richards, J -- Blattner, F R -- New York, N.Y. -- Science. 1979 Dec 14;206(4424):1303-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/117549" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Biological Evolution ; DNA, Recombinant ; *Genes ; Immunoglobulin Constant Regions/*genetics ; Immunoglobulin Heavy Chains/*genetics ; Immunoglobulin gamma-Chains/*genetics ; Immunoglobulins/*genetics ; Liver ; Mice ; Mice, Inbred BALB C ; Nucleic Acid Precursors/genetics ; RNA, Messenger/genetics ; Transcription, Genetic
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    NCI bioassay program (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-24
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Upton, A C -- New York, N.Y. -- Science. 1979 Aug 24;205(4408):746.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/462186" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Carcinogens ; *Drug Evaluation, Preclinical ; *National Institutes of Health (U.S.) ; United States
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    BK virus DNA: complete nucleotide sequence of a human tumor virus (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-26
    Description: The complete DNA sequence of the human papovavirus BK is presented. From the 4963 base-pair sequence of BK virus (MM strain), the amino acid sequence of at least five proteins can be deduced: a T antigen and a t antigen, which share amino terminal peptides; proteins VP2 and VP3, which share 232 amino acids; and protein VP1, whose coding sequence overlaps those for VP2 and VP3 by 113 nucleotides but is read in a different frame. The gene loci and the arrangement of genes are strikingly similar in BK virus and simian virus 40 (SV40). The sequence of the deduced proteins in BK virus shares 73 percent amino acid homology with those in SV40, whereas the DNA sequence of the two viruses shares 70 percent homology, suggesting close evolutionary relationship. However, the repeated DNA sequences in the noncoding regions of these viruses are different.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yang, R C -- Wu, R -- New York, N.Y. -- Science. 1979 Oct 26;206(4417):456-62.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/228391" target="_blank"〉PubMed〈/a〉
    Keywords: Antigens, Viral/genetics ; BK Virus/*genetics ; Base Sequence ; Codon ; DNA, Viral/*genetics ; Genes ; Genes, Regulator ; Polyomavirus/*genetics ; Simian virus 40/genetics ; Viral Proteins/genetics
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    Evolutionary relatedness of viper and primate endogenous retroviruses (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: A retrovirus previously isolated from a tumored Russell's viper is shown by molecular hybridization to be an endogenous virus of this reptilian species. Radio-immunologic techniques revealed that the viper retrovirus is immunologically and, hence, evolutionarily related to endogenous type D retorviruses of Old World primates. These findings extend the number of vertebrate classes possessing endogenous retroviruses and suggest that type D retroviruses may even be more widely distributed in nature than type C retroviruses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Andersen, P R -- Barbacid, M -- Tronick, S R -- Clark, H F -- Aaronson, S A -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):318-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/219480" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigens, Viral/analysis ; Base Sequence ; *Biological Evolution ; *Genes, Viral ; Nucleic Acid Hybridization ; Primates/*microbiology ; Retroviridae/*genetics/immunology ; Snakes/genetics/*microbiology ; Viral Proteins/immunology
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    Risk and responsibility (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bazelon, D L -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):277-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451598" target="_blank"〉PubMed〈/a〉
    Keywords: Decision Making ; Government Agencies ; Jurisprudence ; *Legislation as Topic ; Legislation, Drug ; Power Plants ; *Probability ; Public Opinion ; *Risk ; *Science ; United States
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    Cancer and industrial chemical production (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Davis, D L -- Magee, B H -- New York, N.Y. -- Science. 1979 Dec 21;206(4425):1356, 1358.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/505010" target="_blank"〉PubMed〈/a〉
    Keywords: Environmental Exposure ; Humans ; *Industry ; Neoplasms/*chemically induced/epidemiology ; United States
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  • 40
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    Phenformin ban (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Finkel, M J -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):242.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432643" target="_blank"〉PubMed〈/a〉
    Keywords: Humans ; Phenformin/adverse effects/*standards ; United States ; United States Food and Drug Administration
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    Peer review comes to ADAMHA (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1979 May 11;204(4393):601-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/219482" target="_blank"〉PubMed〈/a〉
    Keywords: *Peer Review ; Research Support as Topic ; United States ; *United States Substance Abuse and Mental Health Services Administration
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  • 42
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    Nuclear transcripts of mouse heavy chain immunoglobulin genes contain only the expressed class of C-region sequences (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: In plasmacytoma cells producing IgG, IgA, or IgM immunoglobulin heavy chains, the large precursors of the heavy chain messenger RNA's contain nucleotide sequences that specify only the expressed class of constant region. This indicates that the switch from one class of heavy chain to another during B cell ontogeny does not occur by altered processing of a complex gene transcript.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marcu, K B -- Schibler, U -- Perry, R P -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1087-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/109919" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cell Line ; Cell Nucleus/metabolism ; Immunoglobulin Constant Regions/*genetics ; Immunoglobulin Heavy Chains/*genetics ; Immunoglobulins/*genetics ; Mice ; Myeloma Proteins/*genetics ; Neoplasms, Experimental/immunology ; Nucleic Acid Precursors/genetics ; Plasmacytoma/immunology ; Poly A/metabolism ; RNA, Heterogeneous Nuclear/genetics ; *Transcription, Genetic
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    Scientists quit antibiotics panel at CAST (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1979 Feb 23;203(4382):732-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/581708" target="_blank"〉PubMed〈/a〉
    Keywords: Animal Feed/*standards ; Anti-Bacterial Agents/*standards ; Economics ; Microbiology ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 44
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    Lasker award stirs controversy (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1979 Jan 26;203(4378):341.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/216074" target="_blank"〉PubMed〈/a〉
    Keywords: *Awards and Prizes ; National Institutes of Health (U.S.) ; *Receptors, Opioid ; *Research ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 45
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    Air is once again rent by drug lag claims (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):283.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451599" target="_blank"〉PubMed〈/a〉
    Keywords: *Drug Evaluation ; Legislation, Drug ; Time Factors ; United States ; *United States Food and Drug Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 46
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    Toxic substances: EPA and OSHA are reluctant regulators (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):28-32.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758675" target="_blank"〉PubMed〈/a〉
    Keywords: Cadmium/standards/toxicity ; Carcinogens/standards ; *Environmental Health ; *Government Agencies ; Humans ; Occupational Medicine/*standards ; Pesticides/toxicity ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 47
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    Study finds sleeping pills overprescribed (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):287-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/219479" target="_blank"〉PubMed〈/a〉
    Keywords: Barbiturates/adverse effects/pharmacology ; Benzodiazepines/adverse effects/metabolism ; Humans ; Hypnotics and Sedatives/*adverse effects ; Metabolic Clearance Rate ; Sleep, REM/drug effects ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 48
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    Carter attempt to limit doctor supply faces tough going in Congress (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Feb 16;203(4381):630-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760209" target="_blank"〉PubMed〈/a〉
    Keywords: Cost Control ; Delivery of Health Care/*economics ; Education, Medical/*manpower ; Legislation as Topic ; Physicians/*supply & distribution ; Training Support/*economics ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 49
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    Federal government faces painful decision on Darvon (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Mar 2;203(4383):857-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/419410" target="_blank"〉PubMed〈/a〉
    Keywords: Dextropropoxyphene/*adverse effects/therapeutic use ; Humans ; *Legislation, Drug ; Substance-Related Disorders ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 50
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    Federal research grants (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-06
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Staats, E B -- New York, N.Y. -- Science. 1979 Jul 6;205(4401):18-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451578" target="_blank"〉PubMed〈/a〉
    Keywords: Government Agencies ; *Research Support as Topic ; United States ; Universities
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 51
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    Simultaneous production of Q and R bands after staining with chromomycin A3 or olivomycin (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-06
    Description: Human and mouse chromosomes, stained with either chromomycin A3 or olivomycin, which bind preferentially to G - C-rich DNA (where G is guanosine and C is cytosine), exhibit a Q or a reverse banding pattern, depending on the wavelength used for excitation. The two complementary banding patterns can be observed in the same metaphase simply by changing the combination of excitation filters. These data suggest, therefore, that in addition to base composition, other factors are involved in the production of chromosome banding by chromomycin A3 and olivomycin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prantera, G -- Bonaccorsi, S -- Pimpinelli, S -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):79-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/86207" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cells, Cultured ; Centromere/ultrastructure ; *Chromomycins ; Chromosomes/*ultrastructure ; *Dna ; Fluorescent Dyes ; Humans ; Mice ; *Olivomycins ; Staining and Labeling
    Print ISSN: 0036-8075
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  • 52
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    Periodicity of deoxyribonuclease I digestion of chromatin (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-25
    Description: Two methods have been used to measure the single-strand lengths of the DNA fragments produced by deoxyribonuclease I digestion of chromatin. The average lengths obtained are muliples of about 10.4 bases, significantly different from the value of 10 previously reported. This periodicity in fragment lengths is closely related to the periodicity of the DNA double helix in chromatin, but the two values need not be exactly the same.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prunell, A -- Kornberg, R D -- Lutter, L -- Klug, A -- Levitt, M -- Crick, F H -- New York, N.Y. -- Science. 1979 May 25;204(4395):855-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441739" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Chromatin/metabolism/*ultrastructure ; Deoxyribonucleases/*metabolism ; Hydrolysis ; Molecular Weight ; Rats
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 53
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    Diabetes drugs: clinical trial (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Prout, T E -- Knatterud, G L -- Meinert, C G -- New York, N.Y. -- Science. 1979 Apr 27;204(4391):362-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/375390" target="_blank"〉PubMed〈/a〉
    Keywords: Clinical Trials as Topic ; Control Groups ; Diabetes Mellitus/*drug therapy ; Drug Evaluation/methods ; Drug Therapy ; Humans ; Hypoglycemic Agents/*toxicity ; Risk Assessment ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 54
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    Margaret Mead: an American phenomenon, 1901--1978 (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Revelle, R -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):39-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/364654" target="_blank"〉PubMed〈/a〉
    Keywords: Anthropology, Cultural/*history ; History, 20th Century ; Societies, Scientific/history ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 55
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    Spectacular science and ponderous process (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Singer, M F -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758684" target="_blank"〉PubMed〈/a〉
    Keywords: *Advisory Committees ; DNA, Recombinant/*standards ; Federal Government ; *Government Regulation ; Research Design/standards ; Safety ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
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  • 56
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    EPA halts most use of herbicide 2,4,5-T (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, J -- New York, N.Y. -- Science. 1979 Mar 16;203(4385):1090-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424734" target="_blank"〉PubMed〈/a〉
    Keywords: 2,4,5-Trichlorophenoxyacetic Acid/adverse effects/*standards ; Abortion, Spontaneous/*chemically induced ; Female ; Government Agencies ; Humans ; Legislation, Drug ; Pregnancy ; Tetrachlorodibenzodioxin/toxicity ; United States
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  • 57
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    Cancer policy announced (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-19
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Oct 19;206(4416):313.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482941" target="_blank"〉PubMed〈/a〉
    Keywords: *Carcinogens ; Government Agencies ; Risk ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 58
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    Jere Goyan brings innovative record to FDA (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Oct 12;206(4415):200-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/482934" target="_blank"〉PubMed〈/a〉
    Keywords: Pharmacy/standards ; United States ; *United States Food and Drug Administration/organization & administration
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 59
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    U.S. beginning to act on banned pesticides (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-29
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jun 29;204(4400):1391-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451572" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Developing Countries ; Humans ; Legislation as Topic ; *Pesticides/poisoning ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 60
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    Henry Waxman still faces an uphill battle (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Mar 30;203(4387):1319, 1321-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/370981" target="_blank"〉PubMed〈/a〉
    Keywords: California ; History of Medicine ; *Legislation as Topic ; Politics ; United States
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  • 61
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    Institute of Medicine report recommends complete overhaul of food safety laws (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-23
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Mar 23;203(4386):1221-2, 1224.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424748" target="_blank"〉PubMed〈/a〉
    Keywords: Carcinogens ; Dose-Response Relationship, Drug ; Food Additives/*standards ; Saccharin ; United States ; United States Food and Drug Administration
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  • 62
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    Major relaxation in DNA rules (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wade, N -- New York, N.Y. -- Science. 1979 Sep 21;205(4412):1238.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472740" target="_blank"〉PubMed〈/a〉
    Keywords: *DNA, Recombinant ; National Institutes of Health (U.S.) ; Research Design/standards ; United States
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  • 63
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    Proposals for ethics boards stir debate (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):285-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451600" target="_blank"〉PubMed〈/a〉
    Keywords: Compensation and Redress ; *Ethics Committees, Research ; Ethics, Medical ; Federal Government ; Government Regulation ; *Human Experimentation ; Humans ; *Informed Consent ; *Professional Staff Committees/legislation & jurisprudence ; Risk ; United States
    Print ISSN: 0036-8075
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  • 64
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    Paul Feyerabend: science and the anarchist (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-11-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Nov 2;206(4418):534-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/386510" target="_blank"〉PubMed〈/a〉
    Keywords: History, 20th Century ; Logic ; *Philosophy ; Science/history ; United States
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  • 65
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    Dollars for drug research flow overseas (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):979-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472730" target="_blank"〉PubMed〈/a〉
    Keywords: Drug Evaluation/methods ; Drug Evaluation, Preclinical/methods ; *Drug Industry ; Economics ; Federal Government ; Government Regulation ; *Internationality ; United States ; United States Food and Drug Administration
    Print ISSN: 0036-8075
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  • 66
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    How to assess cancer risks (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 May 25;204(4395):811, 813, 815-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/441737" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Government Agencies ; Humans ; Mice ; Neoplasms/*chemically induced ; Rats ; Risk ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 67
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    A new and searching look at NSF (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1979 Jun 8;204(4397):1064-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451550" target="_blank"〉PubMed〈/a〉
    Keywords: *Government Agencies ; Legislation as Topic ; Research Support as Topic ; *Science ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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    Should there be a commission on medical education? (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-10
    Description: In its premedical and preclinical phases our present scheme of education for medicine is intellectually deficient, wasteful of money and time, and in urgent need of overhaul. The author defines conditions under which a national commission might possibly set the educational process on the road to reform.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chapman, C B -- New York, N.Y. -- Science. 1979 Aug 10;205(4406):559-62.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451620" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Medical/*standards ; *Professional Staff Committees ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 69
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    Split genes and RNA splicing (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-20
    Description: A number of genes in higher organisms and in their viruses appear to be split. That is, they have "nonsense" stretches of DNA interspersed within the sense DNA. The cell produces a full RNA transcript of this DNA, nonsense and all, and then appears to splice out the nonsense sequences before sending the RNA to the cytoplasm. In this article what is known about these intervening sequences and about the processing of the RNA is outlined. Also discussed is their possible use and how they might have arisen in evolution.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Crick, F -- New York, N.Y. -- Science. 1979 Apr 20;204(4390):264-71.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/373120" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Biological Evolution ; DNA/genetics ; Endonucleases/metabolism ; Eukaryotic Cells/physiology ; *Genes ; Nucleic Acid Precursors/*genetics ; RNA Ligase (ATP)/metabolism ; RNA, Heterogeneous Nuclear/*genetics ; RNA, Messenger/*genetics ; RNA, Ribosomal/genetics ; RNA, Transfer/genetics ; *Transcription, Genetic
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 70
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    Protein and nucleic acid sequence data and phylogeny (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Demoulin, V -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):1036-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472727" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Cytochromes/genetics ; Ferredoxins/genetics ; *Phylogeny ; Proteins/*genetics ; RNA, Ribosomal/*genetics
    Print ISSN: 0036-8075
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  • 71
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    FDA tells senators of doctors who fake data in clinical drug trials (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Holden, C -- New York, N.Y. -- Science. 1979 Oct 26;206(4417):423-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/504984" target="_blank"〉PubMed〈/a〉
    Keywords: Clinical Trials as Topic/*standards ; Drug Industry/standards ; Legislation as Topic ; United States ; United States Food and Drug Administration
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 72
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    Human growth hormone: complementary DNA cloning and expression in bacteria (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-08-10
    Description: The nucleotide sequence of a DNA complementary to human growth hormone messenger RNA was cloned; it contains 29 nucleotides in its 5' untranslated region, the 651 nucleotides coding for the prehormone, and the entire 3' untranslated region (108 nucleotides). The data reported predict the previously unknown sequence of the signal peptide of human growth hormone and, by comparison with the previously determined sequences of rat growth hormone and human chorionic somatomammotropin, strengthens the hypothesis that these genes evolved by gene duplication from a common ancestral sequence. The human growth hormone gene sequences have been linked in phase to a fragment of the trp D gene of Escherichia coli in a plasmid vehicle, and a fusion protein is synthesized at high level (approximately 3 percent of bacterial protein) under the control of the regulatory region of the trp operon. This fusion protein (70 percent of whose amino acids are coded for by the human growth hormone gene) reacts specifically with antibodies to human growth hormone and is stable in E. coli.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Martial, J A -- Hallewell, R A -- Baxter, J D -- Goodman, H M -- New York, N.Y. -- Science. 1979 Aug 10;205(4406):602-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/377496" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Cattle ; DNA, Recombinant/*metabolism ; Escherichia coli/*metabolism ; Growth Hormone/*biosynthesis ; Humans ; Pituitary Gland/metabolism ; Pituitary Neoplasms/metabolism ; *Plasmids ; Poly A/metabolism ; Prolactin/biosynthesis ; *Protein Biosynthesis ; RNA, Messenger/metabolism ; *Transcription, Genetic
    Print ISSN: 0036-8075
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  • 73
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    Differential mortality by sex in fetal and neonatal deaths (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-04-06
    Description: Vital statistics data for the United States from 1922 to 1936 and from 1950 to 1972 were used to analyze fetal and early neonatal mortality. This analysis corroborates the previously established pattern of the sex ratio of fetal deaths--highest from months 3 to 5, lower from months 6 to 7 or 8, and increasing at term. It also indicates a postponement of late fetal deaths into the early infant period. Whereas earlier research reports have described the pattern of the sex ratio of fetal deaths, this report repeats this analysis for a recent national data base. This line of analysis is extended by using the patterns observed in the data to produce an empirical estimate of the primary sex ratio. For 1950 to 1972, this ratio (male to female) is conservatively estimated to be 120:100.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McMillen, M M -- New York, N.Y. -- Science. 1979 Apr 6;204(4388):89-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/571144" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Fetal Death/*epidemiology ; Humans ; *Infant Mortality ; Male ; Pregnancy ; *Sex Ratio ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 74
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    OSHA carcinogen policy delayed (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-01-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, J R -- New York, N.Y. -- Science. 1979 Jan 5;203(4375):35.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/758676" target="_blank"〉PubMed〈/a〉
    Keywords: Carcinogens/standards ; *Government Agencies ; Laboratories/standards ; Occupational Medicine/*standards ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 75
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    Court reluctantly upholds EPA on 2,4,5-T suspension (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 May 11;204(4393):602.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432664" target="_blank"〉PubMed〈/a〉
    Keywords: 2,4,5-Trichlorophenoxyacetic Acid/*standards ; *Government Agencies ; Jurisprudence ; United States
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  • 76
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    Joint statement issued by CDC, HEW, NIEHS (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, R J -- New York, N.Y. -- Science. 1979 Jul 20;205(4403):282.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/221981" target="_blank"〉PubMed〈/a〉
    Keywords: *Cannabis ; Centers for Disease Control and Prevention (U.S.) ; Humans ; National Institutes of Health (U.S.) ; Paraquat/*poisoning ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
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  • 77
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    Regulators defend their turf (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-11-10
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1978 Nov 10;202(4368):603.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/705348" target="_blank"〉PubMed〈/a〉
    Keywords: Economics ; *Environmental Health ; Government Agencies ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 78
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    Uranium mill tailings: Congress addresses a long-neglected problem (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carter, L J -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):191-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694524" target="_blank"〉PubMed〈/a〉
    Keywords: *Environmental Exposure ; Legislation as Topic ; Mining/*standards ; New Mexico ; United States ; *Uranium ; Utah
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 79
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    Changing postdoctoral career patterns for biomedical scientists (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-11-03
    Description: Between 1973 and 1977 the total number of Ph.D.'s holding postdoctoral appointments in the biomedical sciences increased at a rate of more than 550 individuals (12.5 percent) per year. During this same period the total number of doctorates awarded each year in these disciplines showed very little change. The postdoctoral growth can be attributed to substantial increases in both the numbers of recent graduates taking postdoctorals and the length of stay on these appointments. The lack of alternative employment opportunities has contributed heavily to the postdoctoral buildup. Continued growth is likely to have important consequences for biomedical research and research training.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Coggeshall, P E -- Norvell, J C -- Bogorad, L -- Bock, R M -- New York, N.Y. -- Science. 1978 Nov 3;202(4367):487-93.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/705338" target="_blank"〉PubMed〈/a〉
    Keywords: Biology/*manpower/trends ; Education, Continuing/*trends ; Employment ; *Research Support as Topic ; Salaries and Fringe Benefits ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 80
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    Health care economics: the high cost of getting well (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Culliton, B J -- New York, N.Y. -- Science. 1978 May 26;200(4344):883-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/644330" target="_blank"〉PubMed〈/a〉
    Keywords: Bed Occupancy ; Diagnosis/economics ; Economics, Hospital ; *Economics, Medical ; Education, Medical ; Fees and Charges ; Insurance, Health/economics ; Legislation, Medical ; Medical Laboratory Science/economics ; Therapeutics/economics ; United States
    Print ISSN: 0036-8075
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  • 81
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    The quality of medical care (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: This article classifies the major approaches to the assessment of the process and outcomes of medical care. The apparent need to safeguard and enhance the quality of care has led to the institution of mechanisms that subject care to constant review so that deficiencies may be found and corrected. The article reviews the developments that led to the involvement of the federal government in this activity through its sponsorship of professional standards review organizations (PSRO's). The major features of the PSRO's are described and their possible effects discussed. It is too early to say how the PSRO's will fare, but should they fail to accomplish their objectives the pressure for more radical solutions will be difficult to resist.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Donabedian, A -- New York, N.Y. -- Science. 1978 May 26;200(4344):856-64.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/417400" target="_blank"〉PubMed〈/a〉
    Keywords: Computers ; Concurrent Review ; Cost-Benefit Analysis ; Humans ; Medical Records/standards ; Methods ; Peer Review ; Physician-Patient Relations ; Professional Review Organizations/economics/legislation & jurisprudence/standards ; *Quality of Health Care ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 82
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    How valuable are scientific exchanges with the Soviet Union? (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Graham, L R -- New York, N.Y. -- Science. 1978 Oct 27;202(4366):383-90.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/705332" target="_blank"〉PubMed〈/a〉
    Keywords: *Foreign Professional Personnel ; *International Cooperation ; *Science ; Ussr ; United States
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  • 83
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    Research involving human subjects (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-22
    Description: This article reports a study of the activities and performance of institutional review boards to protect human research subjects. Researchers and institutional review board members were generally supportive of the review system, although substantial criticisms were also heard. Institutional review boards had some direct impact on half of the proposals reviewed by requiring either modification of or additional information about proposed research. The data, however, raise questions about the effectiveness of some review board actions, for example, with regard to informed consent. Some policy implications of the study are presented.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gray, B H -- Cooke, R A -- Tannenbaum, A S -- New York, N.Y. -- Science. 1978 Sep 22;201(4361):1094-101.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/356268" target="_blank"〉PubMed〈/a〉
    Keywords: Attitude ; Behavioral Research ; Bioethics ; Clinical Trials as Topic ; Consent Forms ; *Ethical Review ; *Ethics Committees, Research ; *Human Experimentation ; Humans ; Informed Consent ; *Research/standards ; Risk ; Risk Assessment ; United States ; United States Dept. of Health and Human Services
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  • 84
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    Upton OK's Laetrile test on humans (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Broad, W J -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):196.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694525" target="_blank"〉PubMed〈/a〉
    Keywords: Amygdalin/*therapeutic use ; Federal Government ; Humans ; National Institutes of Health (U.S.) ; Neoplasms/*drug therapy ; Research Support as Topic ; United States
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  • 85
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    Care of the aged: old problems in need of new solutions (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: Long-term care for the aged in the United States is overly dependent upon the nursing home. This hospital-like model for long-term care is particularly inappropriate since it imposes a medical solution on a variety of social problems. An adequate long-term care program requires a range of resources in the community as well as in institutions; sheltered housing options seem a desirable alternative to the nursing home. To ensure the quality of nursing home care, the present focus on setting standards for care activities should be abandoned in favor of a focus on care outcomes (physical, mental, and social). In an effort to change our present perverse incentives in the nursing home industry, the proposal is made that nursing homes be reimbursed according to the degree to which patient outcomes meet predicted outcomes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kane, R L -- Kane, R A -- New York, N.Y. -- Science. 1978 May 26;200(4344):913-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/417403" target="_blank"〉PubMed〈/a〉
    Keywords: Aged ; Financing, Government ; Health Facilities, Proprietary ; *Homes for the Aged/economics ; Humans ; Long-Term Care/*methods ; *Nursing Homes/economics/standards ; Socioeconomic Factors ; United States
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  • 86
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    Environmental groups lose friends in effort to control DNA research (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-22
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1978 Dec 22;202(4374):1265-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/725600" target="_blank"〉PubMed〈/a〉
    Keywords: DNA, Recombinant/*standards ; Environment ; Environmental Pollution/prevention & control ; Government Regulation ; Legislation as Topic ; Research Design/*standards ; Risk Assessment ; United States
    Print ISSN: 0036-8075
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  • 87
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    EPA smog standard attacked by industry, science advisers (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marshall, E -- New York, N.Y. -- Science. 1978 Dec 1;202(4371):949-50.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/715452" target="_blank"〉PubMed〈/a〉
    Keywords: *Air Pollutants/toxicity ; Dose-Response Relationship, Drug ; Environmental Exposure ; Government Agencies ; Humans ; Industry ; Ozone/toxicity ; United States
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  • 88
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    Health officials fired up over "tolerable" cigarettes (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1978 Sep 1;201(4358):795-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/684406" target="_blank"〉PubMed〈/a〉
    Keywords: National Institutes of Health (U.S.) ; Nicotine/toxicity ; Smoking/*complications ; Tars/toxicity ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 89
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    The genome of simian virus 40 (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-05
    Description: The nucleotide sequence of SV40 DNA was determined, and the sequence was correlated with known genes of the virus and with the structure of viral messenger RNA's. There is a limited overlap of the coding regions for structural proteins and a complex pattern of leader sequences at the 5' end of late messenger RNA. The sequence of the early region is consistent with recent proposals that the large early polypeptide of SV40 is encoded in noncontinguous segments of DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Reddy, V B -- Thimmappaya, B -- Dhar, R -- Subramanian, K N -- Zain, B S -- Pan, J -- Ghosh, P K -- Celma, M L -- Weissman, S M -- New York, N.Y. -- Science. 1978 May 5;200(4341):494-502.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/205947" target="_blank"〉PubMed〈/a〉
    Keywords: Base Sequence ; Chromosome Mapping ; Codon ; DNA Replication ; DNA, Circular ; DNA, Viral ; Genes ; *Genes, Viral ; Simian virus 40/*genetics ; Transcription, Genetic ; Viral Proteins/genetics
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 90
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    Federal health spending passes the $50-billion mark (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Walsh, J -- New York, N.Y. -- Science. 1978 May 26;200(4344):886-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/347578" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Medical ; *Financing, Government ; Health Services/*economics ; Legislation, Medical ; Medicaid/economics ; Medicare/economics ; Professional Review Organizations/economics ; Research Support as Topic ; Training Support ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 91
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    Origins of prokaryotes, eukaryotes, mitochondria, and chloroplasts (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-01-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schwartz, R M -- Dayhoff, M O -- New York, N.Y. -- Science. 1978 Jan 27;199(4327):395-403.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/202030" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Base Sequence ; *Biological Evolution ; *Cells ; *Chloroplasts ; Computers ; Cytochrome c Group ; *Eukaryotic Cells ; Ferredoxins ; *Mitochondria ; Nucleic Acids ; *Prokaryotic Cells ; Proteins ; RNA, Ribosomal
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 92
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    New rulebook for gene splicers faces one more test (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wade, N -- New York, N.Y. -- Science. 1978 Aug 18;201(4356):600-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/353985" target="_blank"〉PubMed〈/a〉
    Keywords: DNA, Recombinant/*standards ; DNA, Viral/genetics ; Escherichia coli/genetics/pathogenicity ; *Federal Government ; *Government Regulation ; National Institutes of Health (U.S.) ; Research Design/standards ; Risk Assessment ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 93
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    Biological warfare fears may impede last goal of smallpox eradicators (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-07-28
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wade, N -- New York, N.Y. -- Science. 1978 Jul 28;201(4353):329-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/208151" target="_blank"〉PubMed〈/a〉
    Keywords: *Biological Warfare ; Centers for Disease Control and Prevention (U.S.) ; *Smallpox/prevention & control ; United States ; Variola virus ; Virus Cultivation ; *World Health Organization
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 94
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    Antibody diversity (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-06
    Description: Three important aspects of immunoglobulin gene organization and structure have emerged from studies of cloned immunoglobulin kappa chain genes. (i) Multiple variable genes are encoded separately in the genome of both immunoglobulin-producing and uncommitted (embryonic) cells, thereby establishing the evolutionary base for generating immunoglobulin diversity. (ii) These genes exist as many small, closely related families (subgroups) that share close sequence homology largely within their own subgroup. (iii) Comparison of two cloned variable gene segments derived from a single subgroup reveals a feature of their structure that distinguishes them from fixed genes (that is, globin genes) and provides, through extensive surrounding sequence homology, a large target for intergenic recombination. This last observation suggests that a simple recombination mechanism may account for their genetic instability in both germ line and somatic cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Seidman, J G -- Leder, A -- Nau, M -- Norman, B -- Leder, P -- New York, N.Y. -- Science. 1978 Oct 6;202(4363):11-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/99815" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Antibody Specificity ; Base Sequence ; Binding Sites, Antibody/*genetics ; Biological Evolution ; Cell Line ; Embryo, Mammalian/immunology ; *Genes ; Immunoglobulin Constant Regions/*genetics ; Immunoglobulin Light Chains/*genetics ; Immunoglobulin Variable Region/*genetics ; Immunoglobulin kappa-Chains/*genetics ; Immunoglobulins/*genetics ; Mice ; Neoplasms, Experimental/immunology ; Plasmacytoma/immunology ; Recombination, Genetic
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 95
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    Policy recommendations to VA leave NAS at odds with Congress (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-03-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Walsh, J -- New York, N.Y. -- Science. 1978 Mar 3;199(4332):952-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/341315" target="_blank"〉PubMed〈/a〉
    Keywords: *Academies and Institutes ; *Delivery of Health Care ; *Public Policy ; United States ; *United States Department of Veterans Affairs
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 96
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    The problem of defensive medicine (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: Defensive medicine--the use of diagnostic and end-treatment measures explicitly for the purposes of averting malpractice suits--is frequently cited as one of the least desirable effects of the current rise in medical litigation. Many physicians and policy-makers claim that defensive medicine is responsible not only for the increasing costs of health care but the exposing of patients to significant risks of harm from unnecessary procedures. Very little solid information is available about defensive medicine. The studies that have been conducted have been fraught with statistical difficulties and are by no means definitive. Even more important than the issue of defensive medicine is the more basic problem of our system of compensation for medical injuries.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tancredi, L R -- Barondess, J A -- New York, N.Y. -- Science. 1978 May 26;200(4344):879-82.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/644329" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; Cesarean Section/utilization ; Child ; Costs and Cost Analysis ; Craniocerebral Trauma/radiography ; *Defensive Medicine/economics ; Female ; Fetal Monitoring/utilization ; Humans ; *Malpractice/economics ; Physician-Patient Relations ; Pregnancy ; Quality of Health Care ; Surveys and Questionnaires ; United States
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 97
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    Carbon monoxide automobile emissions measured from the interior of a traveling automobile (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-03-17
    Description: During a procedure to monitor carbon monoxide (CO) concentrations inside a traveling car, it was discovered that CO emissions from individual passing vehicles produced accurately measurable increases in the CO concentration. The CO produced by individual vehicles varied by three orders of magnitude; this finding demonstrates that a relatively small number of cars can be responsible for a high percentage of total vehicle CO Emissions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chaney, L W -- New York, N.Y. -- Science. 1978 Mar 17;199(4334):1203-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/75569" target="_blank"〉PubMed〈/a〉
    Keywords: Automobile Driving ; Automobiles/standards ; Carbon Monoxide/*analysis ; Environment ; Rural Population ; United States ; Urban Population ; Vehicle Emissions/*analysis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 98
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    Doctors and their autonomy: past events and future prospects (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-05-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chapman, C B -- New York, N.Y. -- Science. 1978 May 26;200(4344):851-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/347577" target="_blank"〉PubMed〈/a〉
    Keywords: Economics, Medical ; Great Britain ; History, 16th Century ; History, 17th Century ; History, 19th Century ; History, 20th Century ; History, Medieval ; Legislation, Medical/history ; Licensure, Medical/history ; *Malpractice/history ; *Peer Review ; *Physicians ; Quality of Health Care ; Societies, Medical/history ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 99
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    Research in instrument sharing (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-04
    Description: Continued progress in many areas of science depends on access to advanced modern instruments and the data they provide. Costly instruments have been shared in a number of disciplines for many years, and common patterns of shared usage have developed independently. The scientific and financial aspects of large instrument usage are discussed from the points of view of the instrument centers, the users, and the funding agencies. The instrument problem is not one problem but many, and coordinated solutions must be implemented with well-defined goals based on knowledge of the needs of the users and developers of instruments.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Coulter, C L -- New York, N.Y. -- Science. 1978 Aug 4;201(4354):415-20.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663665" target="_blank"〉PubMed〈/a〉
    Keywords: Biophysics/instrumentation ; Cell Biology/instrumentation ; Chemistry/instrumentation ; Computers/supply & distribution ; *Equipment and Supplies ; Government Agencies ; Microscopy, Electron/instrumentation ; Molecular Biology/instrumentation ; Particle Accelerators/supply & distribution ; *Research ; Research Support as Topic ; Spectrum Analysis/instrumentation ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 100
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    Ethics advisory board confronts conception in the test tube (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-13
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Culliton, B J -- New York, N.Y. -- Science. 1978 Oct 13;202(4364):198-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/567844" target="_blank"〉PubMed〈/a〉
    Keywords: Biomedical Research ; *Ethics, Medical ; Federal Government ; Female ; *Fertilization in Vitro ; Government Regulation ; Humans ; In Vitro Techniques ; Infertility/therapy ; Male ; National Institutes of Health (U.S.) ; Research Support as Topic ; Risk Assessment ; United States
    Print ISSN: 0036-8075
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    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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