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  • Articles  (198,709)
  • Institute of Physics  (108,529)
  • American Physical Society  (86,449)
  • Nature Publishing Company
  • 1990-1994  (109,689)
  • 1985-1989  (89,020)
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Year
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  • 1
    Electronic Resource
    Electronic Resource
    Protropin and Public Opinion (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 847-847 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Protropin, Genentech's genetically engineered human growth hormone, has sprouted a big problem—a U.S. federal grand jury indictment charging a Minneapolis, MN physician, a Genentech marketing executive, and Caremark, Protropin's distributor, with engaging in a million-dollar prescription drug ...
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    URL: http://dx.doi.org/10.1038/nbt0994-847
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  • 2
    Electronic Resource
    Electronic Resource
    Environmentally Correct Biotechnology (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 850-850 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] “Biotechnology entails the harnessing of organisms or their components to undertake specific processes thatare, in principle, advantageous to society. There are many applications of biotechnology in fields as diverse as medicine, agriculture, industry, and resource recovery and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0994-850
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  • 3
    Electronic Resource
    Electronic Resource
    Who's afraid of biotech consolidation? (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 858-859 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Most observers broach the subject of consolidation in biotech in anxious and fatalistic terms, as if it were somehow like the coming of the apocalypse. Articles now fashionable quote pessimistic managers discussing their company' s latest Hobson's choice. And self-serious financial analysts advance ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0994-858
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  • 4
    Electronic Resource
    Electronic Resource
    Education and industry, Letter 2 (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 848-848 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: Desmond Mascarenhas, in his article about science education and the biotechnology industry (Bio/Technology 12: 671-673, July), refers to Bernard Dixon's commentary on the Eurobarometer surveys (Bio/Technology 12:113, February). Mascarenhas suggests that the more the public knows ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0994-848b
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  • 5
    Electronic Resource
    Electronic Resource
    BioChem Pharma's big push into diagnostics (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 854-855 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—BioChem Pharma (BCP, Laval, Quebec) has been busy as of late. Its majority-owned subsidiary, BioChem ImmunoSystems, purchased most of the diagnostics business of Ares-Serono (Geneva) for $61 million. Also, BCP announced that it was planning to sell almost half of its 38 ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0994-854
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  • 6
    Electronic Resource
    Electronic Resource
    Going public boosts executive compensation (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 860-860 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—It pays for U.S. biotech companies to go public, at least as far as executive compensation goes. Indeed, biotech executives at the smaller U.S. public companies—a ranking that excludes the 20 public companies with the biggest market capitalizations—currently make annual ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0994-860
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  • 7
    Electronic Resource
    Electronic Resource
    RNA–Related Tools (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 929-929 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] RNA synthesis Cruachem (Glasgow, U.K.) offers isomerically pure 2′-O-Fpmp-protected phosphoramidites. Fpmp groups are stable under ammonolytic conditions used to cleave synthetic RNA from CPG. 2′-O-Fpmp RNA is stable to alkali and endonucleases and can be purified by HPLC and stored ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0994-929
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  • 8
    Electronic Resource
    Electronic Resource
    BST: Science and politics, Letter 1 (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 744-744 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: Russ Hoyle' s article (Bio/Technology 12:570–571, June) on the U.S. Food and Drug Administration's (FDA, Rockville, MD) bovine somatotropin (BST) policy unwittingly strikes at the heart of the dilemma posed by the assessment of veterinary medicinal products and production ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0894-744a
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  • 9
    Electronic Resource
    Electronic Resource
    Biotech's Role in Science Education (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 647-647 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A widely quoted set of surveys conducted by the National Science Foundation indicate that a scant 7 percent of U.S. citizens are scientifically literate—in command of a basic vocabulary and grammar of scientific terms and concepts. A subsequent poll undertaken by the National Institutes of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0794-647
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  • 10
    Electronic Resource
    Electronic Resource
    Credit (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 649-649 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In the article “Shopping for a Contract Research Organization” (Bio/Technology 12: 526–528, May), Figure 1 comes from the lecture notes of “Pharmaceutical Contract Research in the 1990's: A Global Overview” given by Dr. R. Graham Hughes in Bad Hamburg, Germany, on ...
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    URL: http://dx.doi.org/10.1038/nbt0794-649b
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  • 11
    Electronic Resource
    Electronic Resource
    Efficient and Rapid Affinity Purification of Proteins Using Recombinant Fusion Proteases (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 601-605 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In the affinity purification of recombinant fusion proteins, the rate-limiting step is usually the efficient proteolytic cleavage and removal of the affinity tail and the protease from the purified recombinant protein. We have developed a rapid, convenient and efficient method of affinity ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0694-601
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  • 12
    Electronic Resource
    Electronic Resource
    Protein Sequencing as a Tool in Clinical Trials (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 627-628 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Since the mid-1960s, amino acid sequencing has been an invaluable tool for identifying new proteins. Protein sequence data collection accelerated the pace of biotech research throughout the 1970s and 1980s by allowing researchers to search for sequence homology on computer databases. As a result, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0694-627
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  • 13
    Electronic Resource
    Electronic Resource
    Benificial Microalgae (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 707-707 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The demand for additional food supplies, the need for more effective waste disposal, and the shortage of raw materials and energy sources have led people to search for viable solutions to these problems. One of the most promising is using unconventional microbial sources such as microalgae. These ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0794-707
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  • 14
    Electronic Resource
    Electronic Resource
    New Products (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 717-717 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Primer design RightPrimer from BioDisk Software (San Francisco, CA) evaluates all theoretically possible primers for a given sequence and makes selections based on user-specified parameters. It compares primers to a subset of the GenBank database selected by the user and computes a global score, a ...
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    URL: http://dx.doi.org/10.1038/nbt0794-717
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  • 15
    Electronic Resource
    Electronic Resource
    Legal Protection for Recombinant Proteins (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 713-715 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] It comes as a surprise to many biotech inventors that recombinant proteins are sometimes unpatentable. Generally, if a recombinant protein can be shown to be identical to a previously isolated naturally occurring protein, the U.S. Patent and Trademark Office (PTO, Washington, D.C.) will reject the ...
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    URL: http://dx.doi.org/10.1038/nbt0794-713
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  • 16
    Electronic Resource
    Electronic Resource
    Search patents outside U.S. (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 552-552 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: I read with interest the cautionary article by Kathleen Madden Williams entitled “How to Avoid Patent Infringement” (Bio/Technology 12:297-298, March). Ms. Williams' caveat that “you can never be absolutely certain that all relevant patents have been ...
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    URL: http://dx.doi.org/10.1038/nbt0694-552a
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  • 17
    Electronic Resource
    Electronic Resource
    MGI Pharma hopes Salagen makes it profitable (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 560-561 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] FORT COLLINS, Colo.—Founded in 1979 as an agricultural biotechnology company, and reincarnated in 1987 as a pharmaceutical firm focusing on in-licensing compounds in late-stages of development, MGI Pharma (Minneapolis, MN) is finally poised to record its first profits. Indeed, the Food and ...
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    URL: http://dx.doi.org/10.1038/nbt0694-560
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  • 18
    Electronic Resource
    Electronic Resource
    Ordering Up Big MACs (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 586-590 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Both gene therapy and basic studies will need new vectors for the transfer of large fragments of mammalian ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0694-586
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  • 19
    Electronic Resource
    Electronic Resource
    Amyloid Plaque and Diabetes (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 591-594 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] New research suggests Alzheimer's disease and type II diabetes share a similar ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0694-591
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  • 20
    Electronic Resource
    Electronic Resource
    DNA Amplification Fingerprinting Using Arbitrary Mini-hairpin Oligonucleotide Primers (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 619-623 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The enzymatic amplification of DNA directed by very short oligonucleotides of arbitrary sequence produces complex DNA profiles useful for genome analysis and identity testing. Mini-hairpins harboring a “core” arbitrary sequence at the 3′ terminus primed the amplification of a wide ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0694-619
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  • 21
    Electronic Resource
    Electronic Resource
    New Products (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 629-629 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Lab dispenser The 505Dz/RL low-cost, microprocessor-controlled peristaltic dispenser from Watson-Marlow (Wilmington, MA) runs at 300 rpm for precise dosing at flow rates up to 3 liters per minute. It offers an accuracy to ±1% for 10 ml fills. It accepts autoclavable silicone tubing, and ...
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    URL: http://dx.doi.org/10.1038/nbt0694-629
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  • 22
    Electronic Resource
    Electronic Resource
    MedLine update (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 432-433 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: We wish to alert the readers of “Turning on Tumor-Fighting Cells” (Bio/Technology 11: 1117–1119, October) to a series of observations that are very relevant to the problem of lack of effectiveness of anti-tumor “killer cells” in the tumor-bearing host. ...
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    URL: http://dx.doi.org/10.1038/nbt0594-432c
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  • 23
    Electronic Resource
    Electronic Resource
    Errata (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 433-433 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The last sentence of the first full paragraph of “New Approaches to Capillary Isoelectric Focusing of Proteins” (Bio/Technology 12: 409, April) should read “In addition, these methods are extremely accurate for determining an unknown protein's isoelectric ...
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    URL: http://dx.doi.org/10.1038/nbt0594-433b
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  • 24
    Electronic Resource
    Electronic Resource
    Sacrificing current profits for future gains (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 444-445 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Fiscal 1993 should have been a year of clinched teeth and white knuckles for executives in the agbiotech industry. After all, though the 16 agbiotech companies surveyed by Bio/Technology achieved aggregate sales of almost $410 million, they still lost a total of $153.7 million, or ...
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    URL: http://dx.doi.org/10.1038/nbt0594-444
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  • 25
    Electronic Resource
    Electronic Resource
    Expect success in phase III trials this year (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 451-451 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Largely because of significant declines in last year's first quarter, biotech stocks ended 1993 down 15.3 percent overall, with the first tier down 10.9 percent, the second tier down 7.6 percent, and the third tier down 23.4 percent. The group performance continues to represent a mixture of ...
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    URL: http://dx.doi.org/10.1038/nbt0594-451
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  • 26
    Electronic Resource
    Electronic Resource
    Europe takes the lead in health-care reform (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 456-457 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Health-care reform. Among investors, executives, and industry analysts, it has become a buzzword for uncertainty about the future of the pharmaceutical and biotechnology industry in the U.S. Certainly, discussion of U.S. health-care reform is important to the continued success of the industry. The ...
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    URL: http://dx.doi.org/10.1038/nbt0594-456
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  • 27
    Electronic Resource
    Electronic Resource
    The Emergence of Biotechnology in Israel (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 480-486 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Is biotechnology in Israel being run as a nationalized industry for national ...
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    URL: http://dx.doi.org/10.1038/nbt0594-480
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  • 28
    Electronic Resource
    Electronic Resource
    Production, Purification and Immunogenicity of a Malaria Transmission-Blocking Vaccine Candidate: TBV25H Expressed in Yeast and Purified Using Nickel-NTA Agarose (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 494-499 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Malaria, a mosquito-transmitted disease afflicting hundreds of millions of residents living in more than 100 tropical countries, is an immense public health problem. Despite initial successes of vector control and chemotherapy in controlling the spread of malaria parasites, recent progress has been ...
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    URL: http://dx.doi.org/10.1038/nbt0594-494
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  • 29
    Electronic Resource
    Electronic Resource
    Subsidized mining by microbe (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 328-328 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: The article “Mining by Microbe” (Bio/Technology 11: 1250, November) suggests that using gluconic-acid producing bacteria to solubilize phosphate rock would provide an energy-efficient process relative to the usual method of treating die phosphate rock with sulfuric acid, ...
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    URL: http://dx.doi.org/10.1038/nbt0494-328a
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  • 30
    Electronic Resource
    Electronic Resource
    106 U.S. biopharmaceutical firms lose $1.1 billion (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 333-335 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Last year was a prosperous one for U.S. firms, as overall profits soared an average of 19percent compared to 1992, largely because of a healthier economy and company cost cutting. For U.S. biopharmaceutical firms, however, last year was anything but prosperous. ...
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    URL: http://dx.doi.org/10.1038/nbt0494-333
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  • 31
    Electronic Resource
    Electronic Resource
    LifeCell introduces skin replacement for burns (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 338-338 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Surgeonshave long sought a skin replacement for severely burned patients, since the sole treatment for these patients involves transplanting a layer of their intact skin to their burn sites, a painful procedure that often results in severe contracture at the transplant sites. These ...
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    URL: http://dx.doi.org/10.1038/nbt0494-338
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  • 32
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    Resetting the model for long–term success (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 342-345 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have now reached an inflection point in the brief history of the biotechnology industry where the rules of the game are changing, perhaps permanently. This has implications for companies at every stage of growth, but these implications are most profound for the current generation of start-ups ...
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    URL: http://dx.doi.org/10.1038/nbt0494-342
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  • 33
    Electronic Resource
    Electronic Resource
    Genetic testing assessed in three reports (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 354-355 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Genetic testing could be a big business for the biotech industry. “This high-tech soothsaying holds enormous promise to prevent or ameliorate diseases—and keep down health care costs—potentially making it one of biotechnology' s hottest niches. Some analysts predict the U.S. ...
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    URL: http://dx.doi.org/10.1038/nbt0494-354
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  • 34
    Electronic Resource
    Electronic Resource
    When is a “Private” Conversation “Public” Disclosure? (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 523-525 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Most scientists find conferences an invaluable way of catching up on the latest developments in their field. Instead of phoning, faxing, and e-mailing, they get a chance to discuss ideas over drinks with their colleagues. The camaraderie that develops during conference-sponsored social hours often ...
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    URL: http://dx.doi.org/10.1038/nbt0594-523
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  • 35
    Electronic Resource
    Electronic Resource
    U.K. supermarket labels recombinant foods (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 351-351 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—CWS Retail (Manchester), a major food retail chain, has introduced self-imposed regulations governing the sale of genetically engineered foods by its Coop supermarkets in Britain. Indeed, CWS' brand of cheese produced with recombinant rennet now bears a new label that reads, ...
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    Lipoproteins and Heart Disease (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 365-370 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Transgenic mice models are helping in the search for new ...
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    Protein Disulfide Isomerase Overexpression Increases Secretion of Foreign Proteins in Saccharomyces cerevisiae (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 381-384 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Overexpression of protein disulfide isomerase (PDI) from a single chromosomally integrated copy in Saccharomyces cerevisiae results in ten–fold higher levels of secretion of human platelet derived growth factor B homodimer, and a four–fold increase in secretion of Schizosaccharomyces ...
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    YACs for the Uninitiated (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 405-405 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The isolation of all the functional elements of the chromosomes of the yeast Saccharomyces cer-evisae—centromeres, telomeres, and potential replication origins (ARS elements)—has meant that artificial yeast chromosomes may be constructed in vitro. The use of such yeast artificial ...
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    Patenting Recipes From Nature's Kitchen (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 406-407 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Taxol, a natural product found in yew trees, has turned out to be one of the most promising cancer treatments to be discovered in decades. For biotechnologists, as well as natural-products researchers, a question often asked is, “How can a naturally occurring chemical like taxol be ...
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    Risk Assessment Redux (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 216-217 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: M.J. Crawley 's letter (Bio/Technology 11:1496, December) commenting on our criticisms (Bio/Technology 11:1323-4, November) of his risk assessment experiments with “transgenic” oilseed rape (Nature 363:620-23, June) makes several points we wish to address: “The ...
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    Reply: Risk Assessment Redux (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 217-217 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] M.J.Crawley replies: Miller et al. seem to think that they have discovered something profound when they point out that “its the product not the process that's important” in thinking about environmental impact analysis of genetically modified organisms (GMOs). Whatever the merits of ...
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    U.K. biotech will boom over next few years (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 230-230 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] OXFORD—U.K. biotechnology is set to boom, according to a recent report by accountants Arthur Andersen (AA, London), who surveyed top management at 166 U.K. biotech start ups. Indeed, the report states that the total turnover of these 166 firms will soon double, rising from $627 million ...
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    A quixotic assault on transgenic plants (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 236-239 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] “No company should be permitted to commercialize a transgenic crop in this country until a strong government program assuring risk assessment of all transgenic plants, and adequate consideration of centers of crop diversity here and elsewhere in the world, is in place.” That stern and ...
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    Regulations are strangling medical devices (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 240-241 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The U.S. medical-device industry—which encompasses products from heart valves to corneal implants—annually racks up $40 billion in sales, while employing more than 35,000 people. It melds several scientific disciplines, involving the application of molecular biology to ...
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    Transformation Systems for Generating Marker–Free Transgenic Plants (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 263-267 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The ability to efficiently introduce foreign genes into plants is key to the success of the emerging plant biotechnology industry. Genetic transformation of crop plants is becoming increasingly routine both in terms of the number of plant species which can be transformed and the frequency of ...
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    Process Validation in the Electronic Age (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 259-261 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Before they can be reliably used, electronic validation systems must themselves be validated: Electronic data generation, capture, processing, and transmission are the norm for biological research. Data on DNA sequences orprotein atomic coordinates can travel around the world, between collaborating ...
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    The State of Fingerpinting (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 294-294 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Four of the most accomplished scientists (dare one say fathers?) of DNA fingerprinting collaborated to edit this newest volume in the Birkhäuser Verlag series on DNA-based identity testing. The book contains 47 chapters written in a variety of depths and styles. Surprisingly, about one-third ...
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    Conservation of Genome Structure Between Rice and Wheat (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 276-278 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have compared the structure of the genomes of rice and hexaploid bread wheat, which speciated more than 60 million years ago, by reciprocal mapping of DNA probes. Results indicate that many wheat chromosomes contain homoeologous genes and genomk DNA fragments in a similar order to that found on ...
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    Another Anniversary for the War on Cancer (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 320-320 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In 1993, 526,000 Americans died of cancer—about 1400 people a day—even though conquering cancer became a national goal in December, 1971, now more than 22 years ago. Though tens of thousands of skilled scientists have been waging war against cancer in their laboratories for a ...
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    Change Is Not Necessarily Progress (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 112-112 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: The comments from Vice President Al Gore's chief domestic policy advisor Dr. Greg Simon (Bio/Technology 11:1504–1505) are not reflective of an environmentally and ethically sensitive administration. He dismisses opposition over PDA's approval of bovine growth hormone as being ...
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    1994 will see stocks trade on own merits (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 120-120 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The continuing investment theme in biotech is stock selection, rather than group selection. We began to see mixed performance in biotech stocks in last year's second quarter, with some stocks reaching new highs and others reaching new lows. We expect this trend to continue for at least the next ...
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    Drug companies must befriend managed care (1994)
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    Nature biotechnology 12 (1994), S. 123-123 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON,D.C.—Managed care is wreaking havoc on the U.S. pharmaceutical industry and with it, of course, the U.S. biopharm-aceutical industry. With their purchasing power—as well as their use of such pharmaceutical-management tools as formularies, therapeutic substitution, and generic ...
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    Three–Dimensional Modeling and Drug Development (1994)
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    Nature biotechnology 12 (1994), S. 147-150 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Has “rational” drug design arrived?: In a University of North Carolina (Chapel Hill) laboratory with no bottles, no chemicals, and only computer screens, scientists wearing goggles are operating a special control arm to try to get a better “feel” for how protein structures ...
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    Bulk Amino–Acid Fermentation: Technology and Commodity Trading (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 152-155 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] As markets for bulk amino acids expand, the major Japanese producers have brought their technology into North America and Europe: Proteins and peptides are “exciting.” Their subunits, on the other hand, the natural L-amino acids, appear as but humble and dowdy precursors: Nutritionally ...
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    Rapid Selection Using G418 of High Copy Number Transformants of Pichia pastoris for High–level Foreign Gene Expression (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 181-184 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Pichia pastoris is a methylotrophic yeast increasingly important in the production of therapeutic proteins. Expression vectors are based on the methanol–inducibte AOX1 promoter and are integrated into the host chromosome. In most cases high copy number integration has been shown to be ...
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    Electrochemiluminescence: A New Diagnostic and Research Tool (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 193-194 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] For decades, scientist have been searching for new nonradioactive detection methods that are stable in air and aqueous solutions, inexpensive, and easy to use. Needless to say, these labels must have at least the sensitivity, selectivity, and reproducibility of existing methods. ...
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    Free Literature (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 198-198 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Reference manual A reference manual detailing Medix Biotech's expanded portfolio is available from Genzyme Diagnostics (Kent, U.K.). The range of products listed includes: Monoclonal, polyclonal, and paired antibodies; antigens; membrane-based rapid test systems; ELIS A test kits; immunoassay ...
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    Clinical trials (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1313-1313 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: Stephen Edgington's article in Bio/Technology (12: 977–981, October) makes much of failed clinical trials. But really, what does anyone expect is going to happen? A clinical trial is, after all, an experiment—its result is not a foregone conclusion. Of course, not every ...
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    Will biotech stocks ever rise again? (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1322-1323 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Chief executive officers will cheer, and brokers will shout, and the momentum players will all come out, when those biotech stocks finally go up again. Another string of clinical set-backs has turned the biotechnology sector's usual autumn rally into a rout. After two years in a bear market, ...
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    Trehalose is a sweet target for agbiotech (1994)
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    Nature biotechnology 12 (1994), S. 1328-1329 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The first specialty products containing trehalose might appear on the market around 1999, or maybe even sooner. Quietly, a new product is edging into the portfolios of agbiotech companies. The product is a sweetner called trehalose, a colorless and odor-free disaccharide made simply of two glucose ...
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    AIDS product development follows its own rules (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1329-1331 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—In matters concerning AIDS, the usual rules and expectations often don't apply. Nowadays, top regulatory officials at the Food and Drug Administration (FDA, Rockville, MD) sometimes seem ahead of AIDS activists and company representatives in trying to accelerate the testing ...
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    Recombinant Proteins Can Be Isolated from E. coli Cells by Repeated Cycles of Freezing and Thawing (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1357-1360 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Repeated cycles of freezing and thawing are sufficient to separate highly expressed recombinant proteins away from the cellular milieu of E. coli. Freezing and thawing liberates recombinant proteins from the bacterial cytoplasm, but does not release the bulk of endogenous E. coli proteins. ...
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    Establishment of Genetic Linkage by Allele–specific Polymerase Chain Reaction: Application to the Lignin Peroxidase Gene Family of Phanerochaete chrysosporium (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1372-1375 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Determining linkage is problematic for genes lacking easily identifiable phenotypes and for organisms without well–defined genetic recombination systems. Phanerochaete chrysosporium with its lignin peroxidase (LiP) gene family typifies these difficulties. We describe an experimental approach ...
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    A Carbohydrate Biosensor Surface for the Detection of Uropathogenic Bacteria (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1376-1378 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have developed a new surface for use in biosensors that is based on a gold plate covered with a specific carbohydrate receptor structure. The carbohydrate, Galα1–4Gal, was bound covalently via a thioalkylcarboxy–spacer, or adsorbed as a neoglycoprotein, to a ...
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    Announcements (1994)
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    Nature biotechnology 12 (1994), S. 1388-1388 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Meetings Dec. 10–14. 34th annual meeting of the American Society for Cell Biology. San Francisco, CA. Info: Geri Goodenough.Tel: 1 301 530 7153. Fax: 1 301 5307139. Dec. 12–13. IBC Conferences meeting on rational drug design advances in structure-based design, discovery, and ...
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    Public opinion (1994)
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    Nature biotechnology 12 (1994), S. 1048-1048 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: I read with interest Bernard Zechendorf s article, “What the Public Thinks About Biotechnology” (Bio/Technology 12:870-875, September). Never before have so many members of the public been asked by so many opinion pollsters about a new technology on which so little ...
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    Atherosclerosis Patents: Clues to the Next Drug Generation (1994)
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    Nature biotechnology 12 (1994), S. 1379-1380 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Atherosclerosis is one of the leading causes of death in the developed world. It is the underlying cause of heart attacks, angina, and some types of stroke. Although the incidence of heart disease has gradually declined in the West during the last decade or so, there has been a rapid rise in heart ...
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    Gene therapy off to slow start (1994)
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    Nature biotechnology 12 (1994), S. 1066-1066 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] WASHINGTON, D.C.—A belief that human gene therapy is still in a very early and unproved phase was echoed often during a recent hearing convened by the House of Representatives' Committee on Science, Space, and Technology, even by some of the technology's most enthusiastic backers. Kenneth ...
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    Shielding Affinity Chromatography (1994)
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    Nature biotechnology 12 (1994), S. 1086-1086 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Pulsing your columns with polymers prevents nonspecific binding and allows elution by temperature ...
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    Large Scale, In Situ Isolation of Periplasmic IGF–I from E. coli (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1113-1117 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Human insulin–like growth factor I (IGF–I) accumulates in both folded and aggregated forms in the fermentation medium and cellular periplasmic space when expressed in E. coli with an endogenous secretory signal sequence. Due to its heterogeneity in form and location, low yield of ...
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    Rewiring Your Company for CANDA/CAPLA Submission (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1132-1133 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The FDA's (Food and Drug Administration, Rockville, MD) 1995 CANDA/CAPLA submission mandate looms just around the corner. Whether you will be filing a computer-assisted new drug application (CANDA) or a computer-assisted product license application (CAPLA), your organization has probably considered ...
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    A High Capacity Microbial Screen for Inhibitors of Human Rhinovirus Protease 3C (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1012-1016 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have developed a high capacity screen for compounds that inhibit the 3C protease of human rhinovirus–1b. The assay uses a recombinant strain of Escherichia coli expressing both the protease and a tetracycline resistance–conferring protein modified to contain the minimal protease ...
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    Turning Up the Heat On Rational Drug Design (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1083-1085 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Using enthalpy to probe binding interactions may put companies on the drug development fast ...
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    Molecular Neurosurgery: Mending the Broken Brain (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1075-1080 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Novel molecular technologies may enable effective treatments for crippling brain ...
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    Perfusion Confusion: How Does High–Speed Chromatography Work? (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 1090-1090 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Do PerSeptive Biosystems' perfusion patents cover products sold by Pharmacia Biotech and ...
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    Biotech in Thailand (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 954-954 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Think of a country where 90 percent of members of the population support biotechnology as a worthwhile area for scientific research, where 83 percent are willing for their children to undergo gene therapy to cure an otherwise fatal disease, and where 86 percent of people are aware that genetically ...
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    Groupe Limagrain is a top cooperative (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 964-966 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The old joke goes like this. A college student, scanning the bulletin board outside his professor's office, inches his finger down the long grade list. He notices that someone has circled the bottom four students and written, “Farm co-op managers.” Farm cooperatives in the U.S. have ...
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    Unfortunately, the biodiversity treaty is dead (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 968-969 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] For all practical purposes, the biodiversity treaty is dead. From its beginnings before the 1992 Earth Summit in Rio De Janeiro, the treaty, known in formal diplomatic parlance as the United Nations Convention on Biological Diversity, has been starcrossed. In August, more than a year after the ...
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    Trade associations need better negotiating skills (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 972-973 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] When I was special assistant to Frank Young, who was then the commissioner of the U.S. Food and Drug Administration (FDA, Rockville, MD), he used to speak admiringly of the “Waxman technique” for attaining public policy goals. Tenacious, but patient, Congressman Henry Waxman (D-CA) ...
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    Still Waters Run Deep (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 983-987 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Technology improvement and greater quality awareness is changing the way water is produced for ...
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    It's Time for the U.S. to Rejoin UNESCO (1994)
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    Nature biotechnology 12 (1994), S. 104-104 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] As the first term of Ronald Reagan's presidency drew to a close, the “Great Communicator” announced to a largely disinterested constituency that 1984 would be the final year of U.S. participation in the United Nations Educational, Scientific, and Cultural Organization (UNESCO). From an ...
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    Chiron teams with Viagene in gene therapy (1994)
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    Nature biotechnology 12 (1994), S. 16-18 
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    Notes: [Auszug] NEW YORK—Chiron's (Emery-ville, CA) recent alliance with Viagene (San Diego, CA) to pursue gene-therapy therapeutics is yet another example of Chiron's commitment to collaborate with early-stage biopharmaceutical firms to deepen its long-term product pipeline. Such alliances can save money, ...
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    Analyzing the opportunities in U.S. cotton (1994)
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    Nature biotechnology 12 (1994), S. 22-23 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The agbiotech industry is fascinated with cotton. The attraction is understandable. About 13 million acres are planted in the U.S. Outside the U.S., cotton is grown in over 70 countries and on approximately 71 million acres. While the area planted to cotton is paltry in comparison to global wheat ...
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    Clinton's new environmental–trade policy (1994)
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    Nature biotechnology 12 (1994), S. 26-27 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Coming on the heels of the North American Free Trade Agreement (NAFTA), the Clinton administration's new environmental-technologies export policy hardly made a blip on media radar screens. With the NAFTA struggle over, the pundits turned their attention to President Clinton's trip to an Oregon ...
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    Gene Therapy: Biotech's n + 1 Technology (1994)
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    Nature biotechnology 12 (1994), S. 42-45 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] What they are teaching at MIT's Sloan School of Management: The history of technological advancement shows that innovation is initially often dismissed as impractical—and ignored. By the time the incumbent technology recognizes the new technology's threat it is too late: The new technology ...
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    Perpetual Rumenation (1994)
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    Nature biotechnology 12 (1994), S. 10-10 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Imagine a complex, exquisitely controlled biological process that runs virtually nonstop, at high temperature, for an entire lifetime. Ruminant digestion is that process, unmatched by anything else in the natural or industrial world. It's no surprise, then, that genetic engineers have had their ...
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    Corange sinks $206 million into PDL (1994)
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    Nature biotechnology 12 (1994), S. 15-16 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Biopharmaceutical firms are increasingly seeking funding through corporate alliances, since product development is becoming more difficult and more expensive and since accessing pubic equity and even private equity is becoming increasingly troublesome. Indeed, such alliances are ...
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    Two firms tackle cord–blood transplants (1994)
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    Nature biotechnology 12 (1994), S. 23-24 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] FORT COLLINS, Colo.—It was an act of desperation, one that became a topic of discussion on nearly every talk show. Marissa Ayala, a teenager with chronic myelogenous leukemia, was going to die unless she received a bone-marrow transplant. A search of the U.S. National Marrow Donor Program ...
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    Alliance Update (1994)
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    Nature biotechnology 12 (1994), S. 28-28 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Companies Agreement Aastrom Biosciences &Cobe The two will commercialize Aastrom's Stem Cell Expansion System, focusing on bone-marrow and stem-cell transplantation resulting from high-dose chemotherapy, with an aim of transforming these transplants from acute-care procedures into simplified ...
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    As We Live And Breathe: Free Radicals and Aging (1994)
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    Nature biotechnology 12 (1994), S. 37-40 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Correlative evidence from a number of fields suggests they may be key: You've set off on your run, your pulse gradually rises above 130, your breathing becomes heavier. Thoughts tumble through your mind like the leaves falling from the trees around you. Step by step your mind clears as you focus on ...
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    The President and Bioremediation (1994)
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    Nature biotechnology 12 (1994), S. 8-8 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: Russ Hoyle's commentary last month, “Clinton's doomed technology-development policy” (Bio/Technology 11:1226, November) was seriously misinformed in asserting the lack of a Clinton Administration commitment to assisting private sector development of the promising ...
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    Education and industry, Letter 1 (1994)
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    Nature biotechnology 12 (1994), S. 848-848 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] To the editor: It was refreshing to see Desmond Mascarenhas raising the issue of how industry can play a pivotal role in promoting biotechnology education in schools and in the community (Bio/Technology 12:671-673, July). Although companies have been slow to commit people and resources, industry ...
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    Genzyme sinks at least $80 million in Celtrix (1994)
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    Nature biotechnology 12 (1994), S. 852-854 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] FORT COLLINS, Colo.—With public and private financing in the doldrums, U.S. biopharmaceutical firms have shied away from stock offerings to fund product development. Yet the deep pockets of the world's established pharmaceutical firms have at least partly filled this funding void. Recent ...
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    Analyzing the future of worldwide agbiotech (1994)
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    Nature biotechnology 12 (1994), S. 859-860 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] This spring an eclectic collection of about 100 gathered at Trinity College in Cambridge, U.K. Name tags were not necessary. Speakers were not introduced with the customary elaborate recitations. Many were old friends or jealous enemies. Under the auspices of the generous British grocery baron, ...
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    EU plans to streamline GMO regulations (1994)
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    Nature biotechnology 12 (1994), S. 864-864 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] OXFORD—The European Union's (EU, Brussels) European Commission (EC)—the EU's regulation-drafting body—is preparing to streamline the regulations governing the contained use of genetically modified organisms (GMOs) and the deliberate release into the environment of GMOs. Indeed, ...
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    Transgene Inactivation: Plants Fight Back! (1994)
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    Nature biotechnology 12 (1994), S. 883-888 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Desirable new phenotypes created by the introduction of foreign DNA into plants are frequently unstable following propagation, leading to a loss of the newly acquired traits. This genetic instability is due not to deletion or mutation of the introduced DNA but rather to the inactivation of the ...
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    Expansion of Hematopoietic Progenitor Cell Populations in Stirred Suspension Bioreactors of Normal Human Bone Marrow Cells (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 909-914 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have investigated the potential of stirred suspension cultures to support hematopoiesis from starting innocula of normal human bone marrow cells. Initial studies showed that the short–term maintenance of both colony–forming cell (CFC) numbers and their precursors, detected as ...
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    Branched DNA Signal Amplification (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 926-928 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A virtual revolution in molecular biology began nearly ten years ago with the invention of the poly-merase chain reaction (PCR).1 The “breakthrough” in this technology was an easy method to amplify a target molecule. If imitation is the greatest form of flattery, PCR has been one of the ...
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    Putting Value on Biotech Drugs (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 743-743 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Drug makers, large and small, must put cost containment and global health-care reform considerations into any equation about clinical drug development. It is no longer enough to prove that your drug is safe and effective to get it through the clinic and into the market. You also need to show that ...
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    Tech names (1994)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 12 (1994), S. 745-745 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: What's in a name? For biotech companies living in the illuminated goldfish bowl of the investment community, quite a lot. The term biotech may not be precise, but it does convey a particular image to the medical and investing public. Biotech company is shorthand for a research-based ...
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