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  • Q1-390  (1,698)
  • General Chemistry
  • Limnology
  • 2020-2024  (1,704)
  • 1945-1949  (794)
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  • 101
    Publication Date: 2024-04-05
    Description: Water is usually referred to as the ‘Molecule of Life’. It constitutes the most abundant molecule in living (micro)organisms and is also essential for critical biochemical reactions, both for the global functioning and maintenance of Ecosystems (e.g., Photosynthesis) and individual (microbial) cells (e.g., ATP hydrolysis). However, most of Earth’s terrestrial environments present deficiencies in bioavailable water. Arid environments cover around a third of the land’s surface, are found on the six continents and, with the anthropogenic desertification phenomenon, will increase. Commonly defined by having a ratio of precipitation to potential evapotranspiration (P/PET) below 1, arid environments, being either hot or cold, are characterized by scant and erratic plant growth and low densities in macro-fauna. Consequently, these ecosystems are microbially mediated with microbial communities particularly driving the essential Na and C biogeochemical cycles. Due to the relatively simple trophic structure of these biomes, arid terrestrial environments have subsequently been used as ideal ecosystems to capture and model interactions in edaphic microbial communities. To date, we have been able to demonstrate that edaphic microorganisms (i.e., Fungi, Bacteria, Archaea, and Viruses) in arid environments are abundant, highly diverse, different from those of other terrestrial systems (both in terms of diversity and function), and are important for the stability and productivity of these ecosystems. Moreover, arid terrestrial systems are generally considered Mars-like environments. Thus, they have been the favored destination for astro(micro)biologists aiming to better understand life’s potential distribution and adaptation strategies in the Universe and develop terraforming approaches. Altogether, these points demonstrate the importance of significantly improving our knowledge in the microbial community composition (particularly for Fungi, Archaea and Viruses), assembly processes and functional potentials of arid terrestrial systems, as well as their adaptation mechanisms to aridity (and generally to various other environmental stresses). This Research Topic was proposed to provide further insights on the microbial ecology of hot and cold arid edaphic systems. We provide a detailed review and nine research articles, spanning hot and cold deserts, edaphic, rhizospheric, BSC and endolithic environments as well as culture-dependent and -independant approaches.
    Keywords: QR1-502 ; Q1-390 ; xeric stress ; Arid environment ; desert ; Nitrogen ; environmental gradients ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 102
    Publication Date: 2024-04-01
    Description: Cet ouvrage est le fruit de l’une des premières « expertises collégiales » coordonnées par l’Institut de recherche pour le développement (IRD). Il fait le bilan des connaissances sur la présence, préoccupante, du mercure en Amazonie, sur ses effets sur l’environnement et la santé. Il se conclut par un certain nombre de recommandations opérationnelles. Il existe deux modes spécifiques de contamination humaine par le mercure : l’exposition des travailleurs de l’or (orpailleurs ou raffineurs) aux vapeurs de mercure dégagées lors des opérations d’enrichissement du minerai aurifère et de purification des lingots ; l’exposition de la population à un dérivé du mercure, le méthylmercure, principalement par la consommation de poissons eux-mêmes contaminés. Le premier mode, direct, de contamination peut entraîner des troubles de la santé du fait d’expositions prolongées et répétées. Ceux-ci concernent les voies respiratoires, le système gastro-intestinal et le système nerveux central, ce dernier pouvant être l’objet d’altérations irréversibles. Le caractère souvent clandestin et précaire des activités d’orpaillage ne favorise pas l’usage de techniques qui éviteraient ou du moins réduiraient cette contamination. La seconde forme d’exposition est beaucoup plus difficile encore à maîtriser. La méthylation du mercure, issu de l’orpaillage mais aussi contenu dans les sols à l’état « naturel », relève d’activités bactériennes dans des milieux aquatiques privés d’oxygène et riches en matière organique. L’exportation du mercure est facilitée par la déforestation – les sols dénudés favorisent sa libération – et par l’aptitude de ce métal à se complexer aux fines suspensions argilo-organiques véhiculées par les eaux. La contamination des poissons est l’étape suivante de la chaîne de transfert vers l’homme : comme, pour beaucoup de populations amazoniennes, leur consommation représente la source essentielle de protéines, elle constitue un agent d’exposition quasi quotidienne au méthylmercure dans l’ensemble de l’Amazonie et non dans les seules régions d’orpaillage. Cette imprégnation continue entraîne essentiellement l’apparition, tant chez l’adulte que chez l’enfant, d’atteintes neurologiques sévères, plus graves encore chez le fœtus au moment de la formation des organes. À partir de ces constats, un certain nombre de recommandations sont avancées : la mise en place d’un observatoire amazonien de surveillance, la création d’une structure d’encadrement de l’orpaillage, l’usage généralisé d’équipements de protection contre les vapeurs de mercure, diverses mesures techniques destinées à réduire l’impact du mercure dans l’environnement, une meilleure diffusion de l’information de base sur les risques encourus, l’adoption d’habitudes alimentaires prévenant l’exposition régulière au méthylmercure, une amélioration des suivis sanitaires.
    Keywords: H1-99 ; Q1-390 ; mine ; Guyane française ; sédimentation lacustre ; or ; Amazonie ; exploitation du sous-sol ; mercure ; eau continentale ; Brésil ; contamination ; santé publique ; toxicité ; cycle biogéochimique ; groupe à risque (santé publique) ; thema EDItEUR::N History and Archaeology::NH History
    Language: French
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  • 103
    Publication Date: 2023-12-21
    Description: There is abundant evidence showing a strong association between trauma exposure, psychotic symptoms, and posttraumatic stress disorder (PTSD). Early trauma exposure contributes to the formation of psychotic symptoms and the development of psychotic disorders or severe mental illnesses such as schizophrenia, bipolar disorder, and treatment-refractory major depression. Furthermore, among persons with psychotic disorders, multiple traumatization over the lifetime is common, due to factors such as social stigma, the criminalization of severe mental illness, and increased vulnerability to interpersonal victimization. In addition to these factors is the traumatic nature of experiencing psychotic symptoms and coercive treatments such as involuntary hospitalization and being placed in seclusion or restraints. Not surprisingly, these high rates of trauma lead to high rates of PTSD in people with psychotic disorders, which are associated with more severe symptoms, worse functioning, and greater use of acute care services. In addition to the impact of trauma on the development of psychotic disorders and comorbid PTSD, traumatic experiences such as childhood sexual and physical abuse can shape the nature of prominent psychotic symptoms such as the content of auditory hallucinations and delusional beliefs. Additionally, traumatic experiences have been implicated in the role of ‘stress responsivity’ and increased risk for transition to psychosis in those identified as being at clinical high risk of developing psychosis. Finally, although the diagnostic criteria for PTSD primarily emphasize the effects of trauma on anxiety, avoidance, physiological over-arousal, and negative thoughts, it is well established that PTSD is frequently accompanied by psychotic symptoms such as hallucinations and delusions that cannot be attributed to another DSM-V Axis I disorder such as psychotic depression or schizophrenia. Understanding the contribution of traumatic experiences to the etiology of psychosis and other symptoms can inform the provision of cognitive behavioral therapy for psychosis, including the development of a shared formulation of the events leading up to the onset of the disorder, as well as other trauma-informed treatments that address distressing and disabling symptoms associated with trauma and psychosis. Until recently the trauma treatment needs of this population have been neglected, despite the high rates of trauma and PTSD in persons with psychotic disorders, and in spite of substantial gains made in the treatment of PTSD in the general population. Fortunately, progress in recent years has provided encouraging evidence that PTSD can be effectively treated in people with psychotic disorders using interventions adapted from PTSD treatments developed for the general population. In contrast to clinician fears about the untoward effects of trauma-focused treatments on persons with a psychotic disorder, research indicates that post-traumatic disorders can be safely treated, and that participants frequently experience symptom relief and improved functioning. There is a need to develop a better understanding of the interface between trauma, psychosis, and post-traumatic disorder. This Frontiers Research Topic is devoted to research addressing this interface.
    Keywords: R5-920 ; RC435-571 ; BF1-990 ; Q1-390 ; Psychosis ; PTSD ; Auditory Hallucinations ; Negative Symptoms ; Childhood Trauma ; Trauma ; Psychological Interventions ; Lived Experience ; bic Book Industry Communication::M Medicine
    Language: English
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  • 104
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: This Special Issue gathers papers reporting research on various aspects of remote sensing of Sea Surface Salinity (SSS) and the use of satellite SSS in oceanography. It includes contributions presenting improvements in empirical or theoretical radiative transfer models; mitigation techniques of external interference such as RFI and land contamination; comparisons and validation of remote sensing products with in situ observations; retrieval techniques for improved coastal SSS monitoring, high latitude SSS and the assessment of ocean interactions with the cryosphere; and data fusion techniques combining SSS with sea surface temperature (SST). New instrument technology for the future of SSS remote sensing is also presented.
    Keywords: Q1-390 ; n/a ; satellite salinity ; one-dimensional (1D) aperture synthesis radiometer ; smos ; Gulf of Maine ; retrieval errors ; Aquarius ; combined active/passive SSS retrieval algorithm ; ocean surface roughness ; upwelling ; salt transport ; quality assessment ; sea ice ; SMOS ; microwave radiometry ; Arctic Gateways ; Aquarius satellite ; validation ; sea surface temperature ; water transport ; forward model ; river discharge ; sea surface salinity ; remote sensing ; retrieval algorithm ; Water Cycle Observation Mission (WCOM) ; SMAP ; microwave remote sensing ; alboran sea ; surface velocity ; Arctic Ocean ; sea surface salinity (SSS) ; coastal ; brightness temperature (TB) ; interferometric microwave imager (IMI) ; Scotian Shelf ; MICAP ; different instrument configurations ; bias characteristics ; mediterranean sea ; Gulf of Mexico ; calibration ; retroflections ; Arctic ocean ; salinity ; Sea Surface Salinity ; Arctic rivers ; Argo ; data processing ; aquarius ; ocean salinity ; Aquarius Validation Data System (AVDS) ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 105
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-01-31
    Description: A plethora of problems from diverse disciplines such as Mathematics, Mathematical: Biology, Chemistry, Economics, Physics, Scientific Computing and also Engineering can be formulated as an equation defined in abstract spaces using Mathematical Modelling. The solutions of these equations can be found in closed form only in special case. That is why researchers and practitioners utilize iterative procedures from which a sequence is being generated approximating the solution under some conditions on the initial data. This type of research is considered most interesting and challenging. This is our motivation for the introduction of this special issue on Iterative Procedures.
    Keywords: QA1-939 ; Q1-390 ; Lipschitz condition ; order of convergence ; Scalar equations ; local and semilocal convergence ; multiple roots ; Nondifferentiable operator ; optimal iterative methods ; Order of convergence ; convergence order ; fast algorithms ; iterative method ; computational convergence order ; generalized mixed equilibrium problem ; nonlinear equations ; systems of nonlinear equations ; Chebyshev’s iterative method ; local convergence ; iterative methods ; divided difference ; Multiple roots ; semi-local convergence ; scalar equations ; left Bregman asymptotically nonexpansive mapping ; basin of attraction ; maximal monotone operator ; Newton–HSS method ; general means ; Steffensen’s method ; derivative-free method ; simple roots ; fixed point problem ; split variational inclusion problem ; weighted-Newton method ; ball radius of convergence ; Traub–Steffensen method ; Newton’s method ; fractional derivative ; Banach space ; multiple-root solvers ; uniformly convex and uniformly smooth Banach space ; Fréchet-derivative ; optimal convergence ; Optimal iterative methods ; basins of attraction ; nonlinear equation
    Language: English
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  • 106
    Publication Date: 2024-04-05
    Description: The transmission route used by many bacterial pathogens of clinical importance includes a step outside the host; thereafter refer to as the non-clinical environment (NCE). Obvious examples include foodborne and waterborne pathogens and also pathogens that are transmitted by hands or aerosols. In the NCE, pathogens have to cope with the presence of toxic compounds, sub-optimal temperature, starvation, presence of competitors and predators. Adaptation of bacterial pathogens to such stresses affects their interaction with the host. This Research Topic presents important concept to understand the life of bacterial pathogens in the NCE and provides the reader with an overview of the strategies used by bacterial pathogens to survive and replicate outside the host.
    Keywords: QR1-502 ; Q1-390 ; Persistence ; Clostridium botulinum ; Listeria ; Escherichia coli ; Biofilm ; packaging ; Legionella ; Viable but non culturable ; Pseudomonas ; protozoa ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 107
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Rapid establishment of seedlings in forest regeneration or afforestation sites after planting is a prerequisite for a successful reforestation. Seedling survival after outplanting can be improved by using high-quality seedling material. Seedling quality consists of several features, such as genetic source, morphological properties, nutritional status, stress resistance, and vitality of the seedlings. Field performance of the seedlings is a complex process which can be affected by many nursery and silvicultural practices. Nursery cultural practices strongly affect seedling quality, which is generally at its highest level during the growth period at the nursery. Afterwards, when the seedlings are transported from the nursery to the planting site (including seedling storage, handling, shipping, and planting practices), the quality of seedlings can only remain the same or decline. To ensure successful regeneration, it is important to produce seedlings that retain their high quality until planting, and to establish them quickly in the forest regeneration site.
    Keywords: Q1-390 ; container parameters ; forest regeneration material ; physiological attributes ; somatic embryogenesis ; Quercus rubra ; antioxidant enzymes ; nursery production ; shortleaf pine ; historical perspective ; maturation ; Appalachia ; bulk density ; Quercus robur L. ; rabbit ; western larch ; Picea abies L. Karst. ; sessile oak ; climate change ; physiological quality ; nursery culture ; Fennoscandia ; pedunculate oak ; elk ; seeds ; survival ; small mammal ; loblolly pine ; Norway spruce ; white oak ; growing media ; germination ; morphological attributes ; embling production ; mechanization ; browse ; contractor ; field performance ; reforestation ; white-tailed deer ; forest biotechnology ; cultural practice ; hybridization ; nutrients ; silviculture ; black locust ; scarification index ; seedling quality ; tree planting machine ; seed size ; herbicide ; artificial regeneration ; restoration ecology ; porosity ; northern red oak ; cryopreservation ; leaf senescence ; tree seedling ; Douglas fir ; Quercus ; growth ; mine reclamation ; forestry ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 108
    Publication Date: 2023-12-21
    Description: The brainstem-limbic regions, including the superior colliculus, pulvinar and amygdala, receive direct perceptual information as a rapid, coarse, subcortical sensory system bypassing early sensory cortical systems, and play a central role in innate behaviors, including motivated and avoidance behaviors. Recent human neuropsychological studies including those on cortical blindness suggest that these subcortical sensory pathways are functional in the intact human brain and interact with more evolutionary recent cortical systems. This eBook presents up-to-date advancements in this area and to highlight the functions of the brainstem-limbic regions in a variety of perceptual, cognitive, affective and behavioral domains. We hope that this current Research Topic provides a comprehensive review to understand roles of the subcortical brainstem-limbic regions in some forms of sensory-motor coupling, cognitive and affective functions.
    Keywords: R5-920 ; RC321-571 ; RC435-571 ; BF1-990 ; Q1-390 ; Subcortical visual pathway ; Saccades ; Amygdala ; Pulvinar ; Superior colliculus ; Limbic system ; Cognition ; Emotion ; Faces ; Reward and aversion ; bic Book Industry Communication::M Medicine
    Language: English
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  • 109
    Publication Date: 2024-04-05
    Description: Ranaviruses and other viruses within the family Iridoviridae, infect a wide range of ecologically and commercially important ectothermic vertebrates, i.e., bony fish, amphibians, and reptiles, and invertebrates, including agricultural and medical pests and cultured shrimp and crayfish, and are responsible for considerable morbidity and mortality. Understanding the impact of these various agents on diverse host species requires the combined efforts of ecologists, veterinarians, pathologists, comparative immunologists and molecular virologists. Unfortunately, investigators involved in these studies often work in discipline-specific silos that preclude interaction with others whose insights and approaches are required to comprehensively address problems related to ranavirus/iridovirus disease. Our intent here is to breakdown these silos and provide a forum where diverse researchers with a common interest in ranavirus/iridovirus biology can profitably interact. As a colleague once quipped, “Three people make a genius.” We are hoping to do something along those lines by presenting a collection of research articles dealing with issues of anti-viral immunity, identification of a potentially novel viral genus exemplified by erythrocytic necrosis virus, viral inhibition of innate immunity, identification of novel hosts for lymphocystivirus and invertebrate iridoviruses, and modelling studies of ranavirus transmission. Collectively these and others will exemplify the breadth of ongoing studies focused on this virus family.
    Keywords: QH301-705.5 ; Q1-390 ; risk assessment ; n/a ; CQIV ; mathematical models ; amphibian ; iridovirus ; ISDL ; Exopalaemon carinicauda ; viral load ; virus isolation ; European chub ; outbreak ; Unconventional T cell ; early detection ; susceptible species ; viral immune evasion ; DNA virus ; Rana grylio virus ; antibody ; intracellular localization ; Rana grylio virus (RGV) ; British Columbia ; Iridoviridae ; Andrias davidianus ranavirus ; viral infection ; susceptible-infected (SI) models ; yeast two-hybrid (Y2H) ; prevalence ; host-pathogen interactions ; Pacific herring ; Procambarus clarkii ; Bayesian inference ; eDNA ; amphibians ; Artemia spp. ; ranavirosis ; cross-species transmission ; FV3 ; SHIV ; Gryllus bimaculatus ; Pacific salmon ; NF-?B ; cricket ; IIV-6 ; virus binding ; erythrocytic necrosis virus (ENV) ; envelope protein ; iridovirus core proteins ; emerging infection ; host ; Ranavirus ; white head ; Rana temporaria ; Imd ; biosecurity ; antiviral immunity ; Decapodiridovirus ; endemic disease ; Macrobrachium rosenbergii ; co-immunoprecipitation (Co-IP) ; Common frog ; aquatic animals ; virus surveillance ; immunomodulators ; frog virus 3 ; ELISA ; DIV1 ; megalocytivirus ; Lymphocystis disease virus ; bearded dragon ; susceptibility ; protein interaction ; Pogona vitticeps ; viral erythrocytic necrosis (VEN) ; histopathology ; epidemiology ; native-fish conservation ; viral transmission ; Sparus aurata ; immunohistochemistry ; lizard ; disease dynamics ; immunofluorescence ; transmission modelling ; Macrobrachium nipponense ; interferon ; nonclassical MHC ; heparan sulfate ; ranavirus ; Mexico ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 110
    Publication Date: 2024-04-05
    Description: The early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive clinical and preclinical evidence has shown that traumatic events early in life have profound and persistent effects on hippocampal function and behavior. This research topic focuses on the acute and lasting effects of early-life stress on various developmental processes in the hippocampus, and aims to uncover the molecules that are responsible for early-life stress-programmed effects and underlie resilience or vulnerability to stress-related neuropsychiatric disorders later in life. We hope the articles in this research topic will provide novel insights and stimulate future studies on the mechanisms of early-life stress and brain development.
    Keywords: RC321-571 ; Q1-390 ; development ; molecular mechanism ; early-life stress ; plasticity ; Hippocampus ; psychiatric disorders ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 111
    Publication Date: 2024-04-05
    Description: Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of these organisms with the human host. The outer most layer of a fungal cell is the cell wall, and together with the secreted components into the extracellular compartment, are the first lines of contact with the host cells. This interaction is critical for tissue adhesion, colonization and damage. In addition, these fungal extracellular components will define the outcome of the interaction with the host immune cells, leading either to the establishment of a protective antifungal immune response or to an immune-evasive mechanism by the fungal cell. On the other hand, our immune system has effectively evolved to deal with fungal pathogens, developing strategies for cell eradication, burden control, or antigen presentation from the innate branch to the adaptive immune response. Here, we provide a series of comprehensive review papers dealing with both aspect of the interaction fungus-immune cells: the role of virulence factors and cell wall components during such interaction, and the recent advances in the study of cellular receptors in the establishment of a protective anti-fungal immune response.
    Keywords: QR1-502 ; Q1-390 ; Candida albicans ; Cell Wall ; Aspergillus ; Histoplasma ; melanin ; Paraccocidioides ; Cryptococcus ; Dermatophytes ; host-fungus interaction ; Candida parapsilosis ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 112
    Publication Date: 2024-04-05
    Description: Historically, cognitive sciences have considered selective attention and working memory as largely separated cognitive functions. That is, selective attention as a concept is typically reserved for the processes that allow for the prioritization of specific sensory input, while working memory entails more central structures for maintaining (and operating on) temporary mental representations. However, over the last decades various observations have been reported that question such sharp distinction. Most importantly, information stored in working memory has been shown to modulate selective attention processing – and vice versa. At the theoretical level, these observations are paralleled by an increasingly dominant focus on working memory as (involving) the attended part of long-term memory, with some positions considering that working memory is equivalent to selective attention turned to long-term memory representations – or internal selective attention. This questions the existence of working memory as a dedicated cognitive function and raises the need for integrative accounts of working memory and attention. The next step will be to explore the precise implications of attentional accounts of WM for the understanding of specific aspects and characteristics of WM, such as serial order processing, its modality-specificity, its capacity limitations, its relation with executive functions, as well as the nature of attentional mechanisms involved. This research topic in Frontiers in Human Neuroscience aims at bringing together the latest insights and findings about the interplay between working memory and selective attention.
    Keywords: RC321-571 ; Q1-390 ; spatial attention ; working memory ; executive attention ; Internal attention ; short-term memory ; selective attention ; serial order ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 113
    Publication Date: 2024-03-29
    Description: There is no shortage of articles and books exploring women’s underrepresentation in science. Everyone is interested--academics, politicians, parents, high school girls (and boys), women in search of college majors, administrators working to accommodate women’s educational interests; the list goes on. But one thing often missing is an evidence-based examination of the problem, uninfluenced by personal opinions, accounts of “lived experiences,” anecdotes, and the always-encroaching inputs of popular culture. This is why this special issue of Frontiers in Psychology can make a difference. In it, a diverse group of authors and researchers with even more diverse viewpoints find themselves united by their empirical, objective approaches to understanding women’s underrepresentation in science today. The questions considered within this special issue span academic disciplines, methods, levels of analysis, and nature of analysis; what these article share is their scholarly, evidence-based approach to understanding a key issue of our time.
    Keywords: BF1-990 ; Q1-390 ; stereotypes ; women in science ; Bias ; leaky pipeline ; sex differences ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 114
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: The inferior colliculus (IC) is a unique structure in the auditory system, located between the primary auditory nuclei of the brainstem and the thalamus. The existence of the complex neural circuits in the auditory brainstem and midbrain, lacking in other sensory systems, has motivated an outpouring of research on the circuitry and physiological properties of the IC. IC neurons receive ascending inputs from over 20 separate sources in the brainstem as well as a dense collection of descending connections from the cortex. It is richly connected to both the left and right ears through these circuits and a major theme in research on the IC has been its role in binaural interactions. A second theme is the role of descending circuits in modulating responses to sound in the IC. A third theme is understanding the sound processing that occurs at the level of the IC, essentially how the representation of sound in the IC differs from that in the two auditory nerves. The representation of sound in the IC is an intermediate step in the development of the cortical representation as well as in the development of many perceptual features of sounds. These characteristics have been documented for a number of computations, including sound localization, masking properties, robustness of the representation, and responses to temporal and spectral properties of sounds. This Research Topic aims to discuss a wide range of aspects of the structure and function of the IC in a way that will facilitate future research.
    Keywords: RC321-571 ; Q1-390 ; ion channel models ; inferior colliculus ; sona ; representation of sound ; internal circuitry ; Neural Pathways ; inhibitory circuits ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 115
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: One last comment concerns the fundamental contributions of Fourier analysis to quantum physics: Quantum mechanics and quantum field theory.
    Keywords: Q1-390 ; self-electrorefining ; hedyphane group ; structural combinatorics ; CuFe2O4 ; Kamchatka ; Raman ; El Dragón ; apatite supergroup ; borate ; ariegilatite ; oyonite ; Tuscany ; gahnite ; magnesioferrite ; Szklary pegmatite ; aurihydrargyrumite ; Au6Hg5 phase ; Trentino ; Peru ; Germany ; cerromojonite ; sulfosalt ; pyrometamorphism ; Bellerberg volcano ; manganese ; gold ; spinel supergroup ; selenium ; CuAl2O4 ; clinokurchatovite ; sharyginite ; Poland ; copper ; kurchatovite ; copper oxide ; antimony ; nabimusaite group ; laachite ; lead ; thermaerogenite ; intercalated hexagonal antiperovskite ; placer ; Lower Silesia ; Eldfell ; Tolbachik volcano ; structural complexity ; nöggerathite-(Ce) ; Val di Fiemme ; Oyon district ; sanidinite ; cuprospinel ; sulfate ; fumarole sublimate ; Cretaio ; polymorphism ; polytypism ; tiberiobardiite ; fiemmeite ; stacking faults ; CO3-group ; Hatrurim Complex ; least-action principle ; phosphorus ; Laacher See ; new oxalate mineral ; Japan ; verneite ; alkaline volcanic rock ; arsenic ; Raman spectroscopy ; single-crystal investigation ; Rusinovite ; Eifel ; Lima department ; Italy ; barioferrite ; configurational entropy ; Hekla ; mercury ; Bolivia ; parafiniukite ; aluminofluoride ; new mineral ; Shadil-Khokh volcano ; Vesuvius ; bournonite group ; Ehime ; calcium ; lillianite homologous series ; chalcophyllite group ; sou?ekite ; silicate ; pyrometamorphic rocks ; crystal structure ; zirconolite ; bismuth ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 116
    Publication Date: 2024-04-05
    Description: Historically, the first observation of a transmissible lytic agent that is specifically active against a bacterium (Bacillus anthracis) was by a Russian microbiologist Nikolay Gamaleya in 1898. At that time, however, it was too early to make a connection to another discovery made by Dmitri Ivanovsky in 1892 and Martinus Beijerinck in 1898 on a non-bacterial pathogen infecting tobacco plants. Thus the viral world was discovered in two of the three domains of life, and our current understanding is that viruses represent the most abundant biological entities on the planet. The potential of bacteriophages for infection treatment have been recognized after the discoveries by Frederick Twort and Felix d’Hérelle in 1915 and 1917. Subsequent phage therapy developments, however, have been overshadowed by the remarkable success of antibiotics in infection control and treatment, and phage therapy research and development persisted mostly in the former Soviet Union countries, Russia and Georgia, as well as in France and Poland. The dramatic rise of antibiotic resistance and especially of multi-drug resistance among human and animal bacterial pathogens, however, challenged the position of antibiotics as a single most important pillar for infection control and treatment. Thus there is a renewed interest in phage therapy as a possible additive/alternative therapy, especially for the infections that resist routine antibiotic treatment. The basis for the revival of phage therapy is affected by a number of issues that need to be resolved before it can enter the arena, which is traditionally reserved for antibiotics. Probably the most important is the regulatory issue: How should phage therapy be regulated? Similarly to drugs? Then the co-evolving nature of phage-bacterial host relationship will be a major hurdle for the production of consistent phage formulae. Or should we resort to the phage products such as lysins and the corresponding engineered versions in order to have accurate and consistent delivery doses? We still have very limited knowledge about the pharmacodynamics of phage therapy. More data, obtained in animal models, are necessary to evaluate the phage therapy efficiency compared, for example, to antibiotics. Another aspect is the safety of phage therapy. How do phages interact with the immune system and to what costs, or benefits? What are the risks, in the course of phage therapy, of transduction of undesirable properties such as virulence or antibiotic resistance genes? How frequent is the development of bacterial host resistance during phage therapy? Understanding these and many other aspects of phage therapy, basic and applied, is the main subject of this Topic.
    Keywords: QR1-502 ; Q1-390 ; lysins ; bacteriophage therapy ; bacterial infection treatment ; biofilms ; immunology ; biocontrol ; regulatory issues ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
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  • 117
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Interaction between language and cognition remains an unsolved scientific problem. What are the differences in neural mechanisms of language and cognition? Why do children acquire language by the age of six, while taking a lifetime to acquire cognition? What is the role of language and cognition in thinking? Is abstract cognition possible without language? Is language just a communication device, or is it fundamental in developing thoughts? Why are there no animals with human thinking but without human language? Combinations even among 100 words and 100 objects (multiple words can represent multiple objects) exceed the number of all the particles in the Universe, and it seems that no amount of experience would suffice to learn these associations. How does human brain overcome this difficulty?
    Keywords: RC321-571 ; Q1-390 ; Brain and functional imaging ; Language ; Cognition ; Emotions ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 118
    Publication Date: 2024-03-29
    Description: Neurophysiological and psychological modifications induced by meditation practice have been consistently addressed by neuroscience. Training meditation practice induced plasticity (Barinaga, 2003; Knight, 2004), and as a consequence several benefit for mental and physical health (Davidson & McEwen, 2012), and cognitive performance. One goal of meditation is to achieve the light of consciousness observing with equanimity (the right distance) clouds of the mind wandering. This Frontiers Research Topic brings together studies from groups of authors whose research focus on neuropsychological systems involved in meditation demonstrating how meditation activates and can modify brain areas, cognitive mechanisms and well-being.
    Keywords: BF1-990 ; Q1-390 ; fMRI ; Meditation ; Attention ; Neuropsychology ; Expertise ; Meta-analysis ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 119
    Publication Date: 2024-04-05
    Description: Spatial-hearing ability has been found to vary widely across listeners. A survey of the existing auditory-space perception literature suggests that three main types of factors may account for this variability: - physical factors, e.g., acoustical characteristics related to sound-localization cues, - perceptual factors, e.g., sensory/cognitive processing, perceptual learning, multisensory interactions, - and methodological factors, e.g., differences in stimulus presentation methods across studies. However, the extent to which these–and perhaps other, still unidentified—factors actually contribute to the observed variability in spatial hearing across individuals with normal hearing or within special populations (e.g., hearing-impaired listeners) remains largely unknown. Likewise, the role of perceptual learning and multisensory interactions in the emergence of a multimodal but unified representation of “auditory space,” is still an active topic of research. A better characterization and understanding of the determinants of inter-individual variability in spatial hearing, and of its relationship with perceptual learning and multisensory interactions, would have numerous benefits. In particular, it would enhance the design of rehabilitative devices and of human-machine interfaces involving auditory, or multimodal space perception, such as virtual auditory/multimodal displays in aeronautics, or navigational aids for the visually impaired. For this Research Topic, we have considered manuscripts that: - present new methods, or review existing methods, for the study of inter-individual differences; - present new data (or review existing) data, concerning acoustical features relevant for explaining inter-individual differences in sound-localization performance; - present new (or review existing) psychophysical or neurophysiological findings concerning spatial hearing and/or auditory perceptual learning, and/or multisensory interactions in humans (normal or impaired, young or older listeners) or other species; - discuss the influence of inter-individual differences on the design and use of assistive listening devices (rehabilitation) or human-machine interfaces involving spatial hearing or multimodal perception of space (ergonomy).
    Keywords: RC321-571 ; BF1-990 ; Q1-390 ; Learning ; HRTF (head related transfer function) ; Sound Localization ; spatial hearing ; adaptation ; training ; binaural cues ; spectral cues ; mulltisensory interaction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 120
    Publication Date: 2024-03-29
    Description: Character can be defined as self-aware knowledge that helps the individual to set goals, values and ethical principles (Cloninger, 2004). This meta-cognitive dimension of human personality involves ‘Theory of Mind’, and is positively related to measures of well-being, mental health, and constructive behavior patterns. Research from at least three different fields, cultural (Shweder, Much, Mahapatra & Park, 1997), personality (Cloninger, 2004), and social psychology (Abele & Wojcizke, 2007) suggest that character can be organized along three broad principles: agency, which is related to the autonomy and the fulfillment and enhancement of the self; communion, which is related to engagement in the protection and relations to others such as families, companies or nations; and spirituality, which is related to the human ability to transcend the self and find and interconnection with all life and appreciation of the whole world around us (Haidt, 2006; Cloninger, 2013). Using the Temperament and Character Inventory (Cloninger, Svrakic & Przybeck, 1993) researchers have found that agentic (i.e., Self-directedness) and communal (i.e., Cooperativeness) values are associated to high levels of happiness, psychological well-being, and less violent behavior. Moreover, low Self-directedness and Cooperativeness is recurrent among individuals with all types of mental health problems, such as, depression, schizophrenia, anxiety disorder, autism spectrum disorders, attention deficit/hyperactivity disorder and et cetera. Spirituality, in coherence with agency and communion, guides the individual to seek self-realization in harmony with others and nature in the changing world (Cloninger, 2013). Seeing character as self-awareness of the self in three dimensions has also been associated to human responsibility and empowerment. This Research Topic will focus on all article types that put forward findings regarding: •Character as a protective factor against mental illness •Character’s association to conduct disorders and violent behavior •Character as a promoter of happiness, life satisfaction, and well-being •The etiology of character •Longitudinal studies on character •Agency, communion, and spirituality as broad dimensions for the conceptualization of positive measures of mental health •Innovative methods to measure or conceptualize character •Non-linear effects of character on mental health •Character as a measure/conceptualization of responsibility •Character in school and work place settings •Character in relation to empowerment.
    Keywords: BF1-990 ; Q1-390 ; Well-being ; Character ; responsibility ; Personality ; Virtues ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 121
    Publication Date: 2024-04-05
    Description: Noninvasive brain stimulation (including Transcranial Magnetic Stimulation (TMS) and Transcranial Current Brain Stimulation (TCS)) can be used both experimentally and therapeutically. In the experimental domain TMS can be applied in single pulses to depolarize a small population of neurons in a targeted brain region. This protocol can be used, for example, to map cortical motor outputs, study central motor conduction time, or evaluate the cortical silent period (a measure of intracortical inhibition) all of which are relevant to neurodevelopment. TMS can also be applied in pairs of pulses (paired pulse stimulation, ppTMS) where two pulses are presented in rapid succession to study intracortical inhibition and facilitation. Trains of repeated TMS (rTMS) pulses can be applied at various stimulation frequencies and patterns to modulate local cortical excitability beyond the duration of the stimulation itself. Depending on the parameters of stimulation the excitability can be either facilitated or suppressed. TCS (including Transcranial Direct Current Stimulation (tDCS), alternating current (tACS), and random noise current stimulation (tRNS) also have the potential to modulate cortical excitability and have also been used to study and modulate cortical activity in healthy and patient populations. The after-effects of rTMS and TCS are thought to be related to changes in efficacy (in either the positive or negative direction) of synaptic connections of the neurons being stimulated, thus these techniques have been used to study and modulate cortical plasticity mechanisms in a number of populations. Recently, researchers have begun to apply these techniques to the study of neurodevelopmental mechanisms as well as the pathophysiology and development of novel treatments for neurodevelopmental disorders. Though there is much promise, caution is warranted given the vulnerability of pediatric and clinical populations and the potential that these techniques have to modify circuit development in a cortex that is in a very dynamic state. This Research Topic hopes to provide an opportunity to share ideas across areas (human and animal researchers, clinicians and basic scientists). We are particularly interested in papers that address issues of choosing a protocol (intensity, frequency, location, coil geometry etc.), populations where noninvasive brain stimulation may have direct impact on diagnostics and treatment, as well as the safety and ethics of applying these techniques in pediatric populations. As many may not be aware of the potential and limitations of noninvasive brain stimulation and its use for research and treatment in this area, this Research Topic promises to have broad appeal. Submissions for all Frontiers article types are encouraged.
    Keywords: RC321-571 ; Q1-390 ; Transcranial Magnetic Stimulation ; development ; Autism Spectrum Disorder ; Depression ; Neurodevelopmental Disorders ; Pediatric Stroke ; Safety ; transcranial direct current stimulation ; noninvasive brain stimulation ; pediatric ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 122
    Publication Date: 2022-01-31
    Description: The goal of this research topic was to motivate innovative research that blurs traditional disciplinary and geographical boundaries. As the scientific community continues to gain momentum and knowledge about how the natural world functions, it is increasingly important that we recognize the interconnected nature of earth systems and embrace the complexities of ecosystem transitions. We are pleased to present this body of work, which embodies the spirit of research spanning across the terrestrial-aquatic continuum, from mountains to the sea. Sincerely, The Editors
    Keywords: GB3-5030 ; GC1-1581 ; Q1-390 ; atmosphere ; dynamics ; ecosystem ; interface ; Carbon ; estuarine ; organic matterriver ; marine ; transition
    Language: English
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  • 123
    Publication Date: 2024-03-31
    Description: Since the discovery of the Warburg effect in the 1920s cancer has been tightly associated with the genetic and metabolic state of the cell. One of the hallmarks of cancer is the alteration of the cellular metabolism in order to promote proliferation and undermine cellular defense mechanisms such as apoptosis or detection by the immune system. However, the strategies by which this is achieved in different cancers and sometimes even in different patients of the same cancer is very heterogeneous, which hinders the design of general treatment options.Recently, there has been an ongoing effort to study this phenomenon on a genomic scale in order to understand the causality underlying the disease. Hence, current “omics” technologies have contributed to identify and monitor different biological pieces at different biological levels, such as genes, proteins or metabolites. These technological capacities have provided us with vast amounts of clinical data where a single patient may often give rise to various tissue samples, each of them being characterized in detail by genomescale data on the sequence, expression, proteome and metabolome level. Data with such detail poses the imminent problem of extracting meaningful interpretations and translating them into specific treatment options. To this purpose, Systems Biology provides a set of promising computational tools in order to decipher the mechanisms driving a healthy cell’s metabolism into a cancerous one. However, this enterprise requires bridging the gap between large data resources, mathematical analysis and modeling specifically designed to work with the available data. This is by no means trivial and requires high levels of communication and adaptation between the experimental and theoretical side of research.
    Keywords: QP1-981 ; QH301-705.5 ; Q1-390 ; Computational Biology ; Metabolic alterations ; Metabolism ; Systems Biology ; Modeling ; Cancer ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 124
    Publication Date: 2024-03-31
    Description: The new millennium has seen a major paradigm shift in insect endocrinology. Great advancements are being made which establish that nutrition and growth play a central role in diverse cellular and physiological phenomena during insect development and reproduction. Nutrition affects rates of growth and is mainly regulated by the function of the pathway of insulin/insulin-like growth factor signalling. This pathway is highly conserved across species and ultimately regulates rates of cell growth and proliferation in growing organs. Insulin and insulin-like peptides (ILPs) are some of the best studied hormones in the animal kingdom and all share a common structural motif and initiate a wide range of closely similar physiological processes in higher organisms. In insects, nutrition, via circulating sugar, promotes release of ILPs from brain neurosecretory cells into the haemolymph, which act on peripheral tissues and stimulate protein synthesis and cell growth. Therefore, insect ILPs are common mediators between nutrition and growth in insects and are functionally analogous to mammalian insulin. The 1980s and 1990s witnessed great progress in elucidation of the physiological and molecular mechanism of action of numerous insect hormones involved in regulation of growth, development, reproduction and metabolism. But the signals for the initiation or termination of controlled events remained largely unknown. ILPs were first identified from the silkmoth Bombyx mori and were named bombyxins, but related peptides were soon found in numerous species and their functions elucidated. The insulin signalling pathway is now recognized as a central factor in the timing of cell proliferation, growth, longevity, reproduction, and reproductive diapause, as well as social behaviour. Recent work has revealed that the insulin signalling pathway is closely integrated with that of various other hormones, including ecdysteroids, the juvenile hormones and neuropeptide(s) such a prothoracicotropic hormone. In addition, the pathway is also linked with both circadian (daily) and photoperiodic (seasonal) clocks potentially providing a basis for its timing function. This Research Topic aims to provide the only current collection of recent advances on insect ILPs. We encouraged submissions on all areas related to identification, characterization, regulation and physiological functions of insect ILPs. We welcomed both full and short reviews and original research articles.
    Keywords: QP1-981 ; Q1-390 ; insulin-like proteins ; timekeeping ; interactions of signaling pathways ; nutrition and metabolism ; Growth and Development ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 125
    Publication Date: 2022-01-31
    Description: O livro Ensino de ciências e matemática III: contribuições da pesquisa acadêmica a partir de múltiplas perspectivas, publicado pela Cultura Acadêmica Editora, tem como objetivo comunicar e oferecer ao debate alguns resultados recentes da produção de pesquisa do Programa de Pós-Graduação em Educação para a Ciência da UNESP, vinculado à Faculdade de Ciências do Campus de Bauru (SP). Assim, reúne, para acesso de pesquisadores, professores e estudantes, nove relatos oriundos de trabalhos de mestrado, doutorado, pós-doutorado e similares, desenvolvidos junto ao referido Programa, e passíveis de contribuir para a discussão e encaminhamento de uma série de questões atuais do ensino de ciências.
    Keywords: Q1-390 ; SCIENCE
    Language: Portuguese
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  • 126
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Afforestation/reforestation (or forestation) has been implemented worldwide as an effective measure towards sustainable ecosystem services and addresses global environmental problems such as climate change. The conversion of grasslands, croplands, shrublands, or bare lands to forests can dramatically alter forest water, energy, and carbon cycles and, thus, ecosystem services (e.g., carbon sequestration, soil erosion control, and water quality improvement). Large-scale afforestation/reforestation is typically driven by policies and, in turn, can also have substantial socioeconomic impacts. To enable success, forestation endeavors require novel approaches that involve a series of complex processes and interdisciplinary sciences. For example, exotic or fast-growing tree species are often used to improve soil conditions of degraded lands or maximize productivity, and it often takes a long time to understand and quantify the consequences of such practices at watershed or regional scales. Maintaining the sustainability of man-made forests is becoming increasingly challenging under a changing environment and disturbance regime changes such as wildland fires, urbanization, drought, air pollution, climate change, and socioeconomic change. Therefore, this Special Issue focuses on case studies of the drivers, dynamics, and impacts of afforestation/reforestation at regional, national, or global scales. These new studies provide an update on the scientific advances related to forestation. This information is urgently needed by land managers and policy makers to better manage forest resources in today’s rapidly changing environments.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; simulation modeling ; shear strength ; stand structure ; vegetation restoration ; surface runoff ; soil and water conservation function ; soil enzymes ; riverbank ; evapotranspiration ; human activity ; afforestation ; Artemisia ordosica ; forest cover ; precipitation variation ; soil bioengineering ; base flow ; Poyang Lake Basin ; in situ calibration ; quantification ; chlorophyll fluorescence ; photoprotection ; remote sensing ; root distribution ; ecosystem model ; CASA ; afforestation ecosystem ; phenophase ; vegetation cover change ; soil characteristics ; Robinia pseudoacacia L. and Pinus tabulaeformis Carr. mixed plantations ; composted pine bark ; water-energy balance ; sediment load ; soil respiration ; energy partitioning ; soil microbial biomass ; transpiration ; net primary productivity ; spatio-temporal scales ; seedling quality ; peat moss ; fresh pine sawdust ; understory plants ; ring-porous trees ; different climatic conditions ; dye tests ; structural equation model ; Loess Plateau ; evapotranspiration (ET) ; Pinus engelmannii Carr. ; empirical statistics ; heat dissipation probes ; MODIS ; slope change ratio of cumulative quantities (SCRCQ) ; soil water balance ; LAI ; climate fluctuation ; BTOPMC model ; living brush mattress ; vegetation greening ; streamflow ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 127
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: In the last decades, inedible lignocellulosic biomasses have attracted significant attention for being abundant resources that are not in competition with agricultural land or food production and, therefore, can be used as starting renewable material for the production of a wide variety of platform chemicals. The three main components of lignocellulosic biomasses are cellulose, hemicellulose and lignin, complex biopolymers that can be converted into a pool of platform molecules including sugars, polyols, alchols, ketons, ethers, acids and aromatics. Various technologies have been explored for their one-pot conversion into chemicals, fuels and materials. However, in order to develop new catalytic processes for the selective production of desired products, a complete understanding of the molecular aspects of the basic chemistry and reactivity of biomass derived molecules is still crucial. This Special Issue reports on recent progress and advances in the catalytic valorization of cellulose, hemicellulose and lignin model molecules promoted by novel heterogeneous systems for the production of energy, fuels and chemicals.
    Keywords: Q1-390 ; QC1-999 ; n/a ; hemicellulose ; catalytic transfer hydrogenolysis reactions ; furfural ; ZSM-5 ; syngas ; renewable aromatics ; Diels–Alder ; lignin ; hydroisomerization ; levulinic acid ; bio-oil upgrade ; metal ferrites ; aromatic ethers ; hierarchical zeolites ; Chilean natural zeolites ; bioethanol ; renewable p-xylene ; desilication ; dimethylfuran ; GC/MS characterization ; biomass ; H-donor molecules ; heterogeneous catalysis ; polyols ; Brønsted acids sites ; spinels ; solketal ; glycerol ; chemical-loop reforming ; zeolite ; cellulose ; insulating oils ; hydrogenolysis ; lignocellulosic biomasses ; bio-insulating oil ; glycidol ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 128
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    Publications scientifiques du Muséum
    Publication Date: 2022-01-31
    Description: Les documents manuscrits de la famille des Jussieu, professeurs de botanique au Jardin du Roy puis au Muséum d’histoire naturelle (1710-1853) ont été acquis en 1858 par le Muséum après la mort d’Adrien de Jussieu. Conservés à la Bibliothèque centrale du Muséum ils forment un fonds riche d’informations pour l’histoire des sciences, particulièrement celle du Jardin et celle de la Botanique. Parmi les plus anciens, se trouve un portefeuille contenant 98 dessins de champignons (en couleur), réalisés vers 1730, par Claude Aubriet (c. 1665-1742) sous la direction d’Antoine de Jussieu (1686- 1758). Claude Aubriet. peintre miniaturiste au Jardin du Roy. est connu pour la réalisation des illustrations des Elémens de botanique que publie Joseph Pitton de Tournefort (1656-1708) en 1694. Ces dessins sont loués pour leur précision par Carl von Linné lui-même. Les dessins de champignons par Aubriet furent exécutés à une période « clé » dans l’histoire de la mycologie, puisqu’en 1729. Pier Antonio Micheli publie dans son ouvrage fondamental (Novo plantarum généra) une étude précise des champignons, accompagnée d’excellentes gravures en noir et blanc. Les réalisations d’Aubriel souvent soignées et fidèles aux modèles, sont précieuses car les représentations en couleurs de champignons sont rarissimes avant la fin du xviiie siècle. Elles témoignent en outre du regard que l’on portait alors sur ces cryptogames, qui apparaissaient bien mystérieux du point de vue de leur organisation, de leur reproduction et. pour tout dire, de leur « existence » même. Cette publication intéressera vivement les mycologues et contribuera a faire connaître Claude Aubriet. En outre, elle souligne le rôle décisif que les illustrateurs scientifiques ont toujours joué au cours de l’histoire.
    Keywords: Q1-390 ; mushroom ; history of science
    Language: French
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  • 129
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Synaptic transmission demands the operation of a highly specialized metabolic machinery involving the transfer of metabolites and neurotransmitters between neurons, astrocytes and microvessels. In the last years, important advances have occurred in our understanding of the mechanisms underlying cerebral activation, neuroglial coupling and the associated neurovascular response. Briefly, exacerbated oxygen consumption in stimulated neurons is thought to trigger glycolytic lactate and glucose transfer from astrocytes which, in turn, obtain these fuels from the microvasculature. Neurotransmitter release is made possible by a combination of transcellular cycles exchanging metabolites between these three compartments, returning eventually the synapsis to its pre-firing situation in the resting periods. In spite of the enormous progresses achieved in recent years, the drivers determining the predominant direction of the fluxes, their quantitative contribution and their energy requirements, have remained until today incompletely understood, more particularly under the circumstances prevailing in vivo. In many instances, progress derived from the implementation of novel methodological approaches including advanced neuroimaging and neurospectroscopy methods. As a consequence, literature in the field became vast, diverse and spread within journals of different specialities. The e-book "Transcellular cycles underlying neurotransmission" aims to summaryze in a single volume, recent progress achieved in hypothesis, methods and interpretations on the trafficking of metabolites between neurons and glial cells, and the associated mechanisms of neurovascular coupling.
    Keywords: RC321-571 ; Q1-390 ; Neuroimaging ; functional MRI ; Neuroglial metabolic coupling ; glutamate-glutamine cycle ; Astrocytic Networks ; Astrocyte-neuron lactate shuttle ; 13C NMR ; Neurovascular coupling ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 130
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Witnessing the rise of nationalism, nativism, and xenophobia in many countries, theories of transculturalism arose, in part, out of the concern that multi- and intercultural identity models have not set themselves sufficiently apart from their own culturalist baggage, thus leaving their doors open to strong nationalistic and ethnocentric orientations. But how can we—how can literature—imagine transcultural communities? This volume attempts to examine whether transculturalism—with its questioning of the dominance of group identity and its return to the individual as a privileged site for cultural multiplicity—can offer guideposts for conceptualizing ‘individual’ diversity without underplaying the role of class, religion, and community. Several contributions to the volume view some of the ‘cosmopolitan’ genealogies of transculturalism cautiously, such as elitist individualism and utopianism, teleologically structured conceptualizations of humanism, and an indiscriminating belief in the ascendency of human universals. Nevertheless, highlighting particular understandings of transculturalism in interpretations of significant literary texts from the Middle Ages to the 21st century amounts, once again and by no small measure, to a political decision—one that historically has often been prompted by a search for commonalities as a basis for the design of universal human rights, international law, transnational structures, and global education.
    Keywords: Q1-390 ; Transculturalism ; Commonality ; Transnationalism ; Cultural Memory ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 131
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Metaphor has been an issue of intense research and debate for decades (see, for example [1]). Researchers in various disciplines, including linguistics, psychology, computer science, education, and philosophy have developed a variety of theories, and much progress has been made [2]. For one, metaphor is no longer considered a rhetorical flourish that is found mainly in literary texts. Rather, linguists have shown that metaphor is a pervasive phenomenon in everyday language, a major force in the development of new word meanings, and the source of at least some grammatical function words [3]. Indeed, one of the most influential theories of metaphor involves the suggestion that the frequency of metaphoric language results because cross-domain mappings are a major determinant in the organization of semantic memory, as cognitive and neural resources for dealing with concrete domains are recruited for the conceptualization of more abstract ones [4]. Researchers in cognitive neuroscience have explored whether particular kinds of brain damage are associated with metaphor production and comprehension deficits, and whether similar brain regions are recruited when healthy adults understand the literal and metaphorical meanings of the same words (see [5] for a review). Whereas early research on this topic focused on the issue of the role of hemispheric asymmetry in the comprehension and production of metaphors [6], in recent years cognitive neuroscientists have argued that metaphor is not a monolithic category, and that metaphor processing varies as a function of numerous factors, including the novelty or conventionality of a particular metaphoric expression, its part of speech, and the extent of contextual support for the metaphoric meaning (see, e.g., [7], [8], [9]). Moreover, recent developments in cognitive neuroscience point to a sensorimotor basis for many concrete concepts, and raise the issue of whether these mechanisms are ever recruited to process more abstract concepts [10]. This Frontiers Research Topic brings together contributions from researchers in cognitive neuroscience whose work involves the study of metaphor in language and thought in order to promote the development of the neuroscientific investigation of metaphor. Adopting an interdisciplinary perspective, it synthesizes current findings on the cognitive neuroscience of metaphor, provides a forum for voicing novel perspectives, and promotes avenues for new research on the metaphorical brain.
    Keywords: RC321-571 ; Q1-390 ; figurative language comprehension ; Schizophrenia ; hemispheric specialization ; embodiment ; right hemisphere damage ; Alzheimer's disease ; Executive Function ; autism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 132
    Publication Date: 2023-12-20
    Description: Visões imaginárias da cidade da Bahia é um trabalho surpreendente. Ele rompe com a aridez de uma geografia clérica, seguindo a orientação de Milton Santos, para o qual “o maior erro que a geografia cometeu foi o de querer ser ciência, em vez de ciência e arte”. A proposta dos autores é a de retornar ao pensamento sartreano, tão caro a Milton. Pensamento que expressa em Esboço de uma teoria das emoções, no qual “... uma emoção remete ao que ela significa. E, o que ela significa é a totalidade das relações da realidade-humana com o mundo”, através da “...queda brusca da consciência no mágico".
 (Retirado da apresentação do livro)
    Keywords: Q1-390 ; SCIENCE ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: Portuguese
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  • 133
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-01-31
    Description: The book entitled Medicinal Plants and Natural Product Research describes various aspects of ethnopharmacological uses of medicinal plants; extraction, isolation, and identification of bioactive compounds from medicinal plants; various aspects of biological activity such as antioxidant, antimicrobial, anticancer, immunomodulatory activity, etc., as well as characterization of plant secondary metabolites as active substances from medicinal plants.
    Keywords: SB1-1110 ; QH301-705.5 ; Q1-390 ; adaptation ; phytochemicals ; antioxidant activity ; Ophiopogon ; secondary metabolites ; Moringa oleifera ; drug discovery ; high-resolution melt curve (HRM) analysis ; catechin ; validation ; sickle cell anemia ; Terminalia macroptera ; Eastern Himalayas ; antioxidant ; P. niruri ; traditional medicine ; DNA barcoding ; allergy ; ?-glucosidase ; ethnobotany ; bioprospecting ; GC-MS ; TQ-ESI-MS ; processing ; mountain plants ; ethnobotanic ; antimicrobial ; activity ; Amazonian ; rbcL ; inflammation ; Pseudomonas aeruginosa ; Nirgundi ; cluster analysis ; plant-food ; ethnopharmacology ; HPLC ; Ficus hirta ; Immulina® ; mechanism of action ; stingless bees ; Brunfelsia ; health ; sesquiterpenoids ; antimicrobial activity ; Moraceae ; Liriope ; NMR ; plant metabolite ; UPLC ; oxidative stress ; antibacterial ; scavenger ; mast cells ; Malian medicinal plants ; essential oil ; Arbutus unedo L. ; Ecuador ; DPPH ; ayahuasca ; Asphodelus ; aerial parts ; antifungal ; saline habitats ; chaste tree ; nutraceuticals ; P. alliaceae ; immunLoges® ; bioproduct ; S. reticulata ; Biophytum umbraculum ; flavonoids ; scopoletin ; carboline alkaloids ; Chrysanthemum coronarium L. ; traditional knowledge ; antioxidants ; anthracene derivatives ; Tetragonula ; caffeoylquinic acids ; BHT ; Eucalyptus ; natural products ; Lannea velutina ; antibiotic resistance ; mass spectrometry ; free radical ; medicinal plants ; cytotoxicity ; skin diseases ; harvest ; proanthocyanidins ; different solvents ; ethnomedicine ; Burkea africana ; basil varieties
    Language: English
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    Frontiers Media SA
    Publication Date: 2024-03-29
    Description: It is acknowledged that practice could induce rapid change or reorganization of the brain’s cellular or neural networks as well as behaviors. Notably, practice relevant to mental or physical approach attracted great attention in this decade. It highlights profound significance both for human evolvement and individual development. Specifically, acquiring fine motor skills is a crucial premise for human being to evolve to modern human by using tools in one side. In the other side, numerous evidences indicated that motor learning involved in limb and trunks promotes the development of individual brain in anatomy and functions. Hence, motor learning is also tightly associated with developmental plasticity. These studies on brain-mind-body practice illuminate a promising way in promoting human brain health. This editorial covers wide range of brain-mind-body practice forms to summarize recent new findings and development from behavioral, physiological, neurobiological and psychological science approaches. In this research topic, we addressed recent findings from theoretical as well as experimental perspective including contributions under the following three headings: 1) intervention studies to investigate the positive effect of brain-mind-body practice on cognition and relevant brain mechanism. The intervention pattern consisted of short-term practice ranging from few hours to several weeks; 2) cross-sectional studies using expert-novice paradigm to explore the behavioral and neural system change induced by extensive brain-mind-body practice; 3) the mediators influence the relationship between practice and health outcomes and 4) new viewpoints on brain-mind-body practice from theoretical perspectives. Here we briefly highlight these articles aiming to provide a deep understanding for the association between practice, plasticity and health for readers. Additionally, it offers new insights for developing possible practice interventions for clinical treatment of neurological dysfunction or disorders.
    Keywords: BF1-990 ; Q1-390 ; Mind-body practice ; Brain ; fMRI ; ERP ; Acute aerobic exercise ; Cognition ; executive control ; Tai Chi Chuan ; intervention ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 135
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually partitioned into three distinct regions, known as classes I, II, and III, which, to varying extents, can be found conserved in nonmammalian jawed vertebrates, such as bony fish, amphibians, and bird lineages. The MHC gene region is characterized particularly by the expression of class I and class II glycoproteins that bind peptides derived from intracellular or extracellular antigens to circulating T-cells. While this expressed antigenic specificity remains the predominant interest with respect to MHC function and polymorphism in a population, a broader concept has emerged that examines the MHC as a multifunctional polymorphic controller that facilitates and regulates genome diversity with a much greater array of functions and effects than just MHC-restricted antigen recognition. This volume of 19 reprints presented by various experts and collected from the Special Issue of Cells on “MHC in Health and Disease” covers a broad range of topics on the genomic diversity of the MHC regulatory system in various vertebrate species, including MHC class I, II, and III genes; innate and adaptive immunity; neurology; transplantation; haplotypes; infectious and autoimmune diseases; fecundity; conservation; allelic lineages; and evolution. Taken together, these articles demonstrate the immense complexity and diversity of the MHC structure and function within and between different vertebrate species.
    Keywords: QH301-705.5 ; Q1-390 ; HCP5 ; n/a ; camels ; MHC ; STK19 ; major histocompatibility complex ; human papillomavirus (HPV) ; T-cell receptor ; T1DGC ; bottleneck ; micro-mini-pigs ; life history ; computational analysis ; hepatocellular carcinoma ; phase ; Bactrian camel ; NSDK ; melanoma ; antigen ; autoimmune disease ; RD ; selection ; disease resistance ; autoimmunity ; ancestral haplotype ; Ski complex ; DXO ; high-throughput sequencing ; conservation genetics ; SVA ; lncRNA ; ankylosing spondylitis ; MHC genes ; viral peptides ; competing endogenous RNA (ceRNA) ; astrogliosis ; birds ; long-fragment super haplotype ; SNP ; RLR ; HLA polymorphism ; 5??3? RNA decay ; expression ; 3??5? mRNA turnover ; orthology ; long-read sequencing ; disease association ; dromedary ; polyomavirus ; MHC-II-associated sperm-egg recognition ; experimental medicine ; single nucleotide polymorphism (SNP) ; fish ; SKIV2L ; production trait ; molecular dynamics simulation ; Macaca fascicularis ; human endogenous retrovirus (HERV) ; concerted evolution ; polymorphism ; Old World camels ; MHC polymorphism ; protocol ; nonclassical ; gene duplication ; microglial reaction ; human leukocyte antigen-E ; SKI2W ; quantitative trait loci (QTL) studies ; antiviral immunity ; human immunodeficiency virus (HIV) ; founder effect ; giant panda ; domain movements ; BK virus ; promoter-proximal transcriptional pause ; type 1 diabetes (T1D) ; RP1 ; miR1236 ; KIR ; synaptic covering ; swine leukocyte antigen ; cynomolgus macaque ; HLA ; kidney transplantation ; ?2m knockout mice ; DOM3Z ; interferon ? ; ethnic populations in China ; ecology ; KIR–HLA pairs ; exosomes ; major histocompatibility complex (MHC) ; MHC-I-based mother-fetus recognition ; RNA quality control ; autoimmune diseases ; NELF-E ; haplotype ; genetic drift ; evolution ; nonhuman primate models ; HLA-B27 ; PNS/CNS interface ; risk genes ; pedigree ; MHC-I- and MHC-II-dependent inter-individual recognition ; regulation ; crested ibis ; reproductive performance ; nephropathy ; cancer ; nuclear kinase ; trichohepatoenteric syndrome ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 136
    Publication Date: 2022-01-31
    Description: Over the last three decades a large body of research has showed that psychosocial job dimensions such as time pressure, decision authority and social support, could have significant implications for psychological distress and well-being. Theoretical models, such as the job demand-control-social support model (JDCS model), the effort-reward imbalance model (ERI model), the job demands-resources model (JDR model) and the vitamin model suggest that distress and positive dimensions at work (well being and motivation) can be considered as two sides of the same coin. If the job is designed to provide the right mix of psychosocial job dimensions (e.g., optimal time pressure, decision authority and social support), work can boost job engagement and well-being as well as productive behaviors at work. When the job is not designed in an optimal way (e.g., too much time pressure and too little decision authority) work can trigger stress reactions and burnout. Although some insight has been gained on how job dimensions could predict distress and well-being, and also into the dimensions that might moderate and mediate these associations; research still faces several challenges. Firstly, most of this research has been cross-sectional in nature, thus making it difficult to conclude on the long-term effects of psychosocial job dimensions. Another challenge concerns how the contextual dimensions can be incorporated into micro-levels models on employee stress and well-being. Nowadays, work is carried out in the context of a wider environment that includes organizational variables. So far the role of the organizational variables in the theoretical frameworks for explaining the relationships between psychosocial job dimensions, employee distress and well-being, has often been underplayed. The main aim of this research topic is to bring together international research from different theoretical and methodological perspectives in order to advance knowledge and practice in the field of work stress.
    Keywords: BF1-990 ; Q1-390 ; Occupational stress ; Engagement ; Burnout ; Recovery dimensions ; Illegitimate tasks ; Individual differences ; Psychosocial job dimensions ; Job satisfaction ; Job strain ; Job resources
    Language: English
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  • 137
    Publication Date: 2024-03-30
    Description: Fragmented, dissociated consciousness can characterize the mind in both wake and sleep states. Dissociative symptoms, during sleep, include vivid dreaming, nightmares, and alterations in objective sleep parameters (e.g., lengthening of REM sleep). During waking hours, dissociative symptoms exhibit disparate characteristics encompassing memory problems, excessive daydreaming, absentmindedness, and impairments and discontinuities in perceptions of the self, identity, and the environment. Llewellyn has theorized that a progressive and enduring de-differentiation of wake and dream states of consciousness eventually results in schizophrenia; a lesser degree of de-differentiation may have implications for dissociative symptoms. Against a background of de-differentiation between the dream and wake states, the papers in this volume link consciousness, memory, and mental illness with a special interest for dissociative symptoms.
    Keywords: R5-920 ; RC435-571 ; BF1-990 ; Q1-390 ; state de-differentiation ; Sleep ; dissociation ; Memory ; Psychopathology
    Language: English
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  • 138
    Publication Date: 2024-04-05
    Description: In the past 20 years protein engineering has been used for the production of proteins mostly for biological applications. The incorporation of artificial amino acids and chemical handles into proteins had made possible the design and production of protein-based materials like hybrid inorganic-organic materials, smart/ responsive materials, monodisperse polymers, and nanoscale assemblies. In the current topic, we cover current uses and envision future applications of materials generated using protein engineering and biosynthesis techniques.
    Keywords: QD1-999 ; Q1-390 ; bacterial collagen ; biomass degradation ; Biocatalysis ; Hydrogels ; human cholinesterase ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 139
    Publication Date: 2023-12-21
    Description: This eBook contains a collection of peer-reviewed original and review articles published in either Frontiers in Endocrinology or Frontiers in Physiology focused on the research topic Optimizing Exercise for the Prevention and Treatment of Type 2 Diabetes.
    Keywords: R5-920 ; RC648-665 ; QP1-981 ; Q1-390 ; treatment ; glucose ; type 2 diabetes ; interval training ; exercise ; metabolism ; cardiometabolic health ; diabetes ; lifestyle ; physical activity ; bic Book Industry Communication::M Medicine
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  • 140
    Publication Date: 2024-03-31
    Description: ATP is normally regarded as the major source of fuel for the energy-demanding processes within cells; however, ATP and other nucleotides (such as ADP, UTP, UDP) can be released from cells, where they act as autocrine or paracrine signaling molecules to affect cellular and tissue functions. In response to various stimuli, ATP and other nucleotides are released from cells in a regulated fashion, either by exocytosis of nucleotide-containing vesicles, or through channels in the plasma membrane. This process occurs in virtually every organ or cell in the body. The cellular effects of these extracellular nucleotides are mediated through specific membrane receptors (P2X and P2Y). These nucleotide signals can be terminated by rapid degradation of the ligand molecules by ecto-nucleotidases (e.g., NTPDases and NPPs). Many of the molecular components essential to nucleotide signaling have been cloned and characterized in detail, and their crystal structures are beginning to emerge. The collected data on extracellular nucleotides suggest a vivid and dynamic signaling system that is modulated by the expression and sensitivity of specific receptors on cells, and by the regulated release and extracellular degradation of ATP and other nucleotides; thus creating a microenvironment of highly regulated paracrine or autocrine control mechanisms. Within the kidney, extracellular nucleotides have emerged as potent modulators of glomerular, tubular, and microvascular functions. These functions include, but are not limited to, tubular transport of water and sodium, tubuloglomerular feedback and auto-regulation, regulation of blood pressure and the microcirculation, oxidative stress, and cell proliferation/ necrosis/apoptosis. Moreover, studies have also uncovered the interaction of nucleotide signaling with other mediators of renal function, such as vasopressin, aldosterone, nitric oxide, prostaglandins, angiotensin II, and the ATP-break down product adenosine. These insights have provided a more comprehensive and cohesive picture of the role of extracellular nucleotides in the regulation of renal function in health and disease. The availability of transgenic mouse models of the key proteins involved in nucleotide signaling has markedly enhanced our understanding of the physiological and pathophysiological roles of the different components of the system in the kidney. Although at a preliminary stage, the pathophysiological significance of this system in the kidney holds the key for the development of an entirely new class of drugs for the treatment of disease conditions, including disorders of water and/or sodium homeostasis, hypertension, acute kidney injury, etc. Thus, the regulation of renal function by extracellular nucleotides is clearly emerging as a distinct field and discipline in renal physiology and pathophysiology that has the potential to develop new drug treatments. In this e-book, we bring together a spectrum of excellent papers by leading experts in the field which present and discuss the latest developments and state-of-the-art technologies.Last but not least, we thank all the authors for contributing their valuable work and the Frontiers in Physiology Editorial Office for bringing out this e-book.
    Keywords: QP1-981 ; Q1-390 ; purinergic receptors ; Extracellular nucleotides ; Adenosine ; polycystic kidney disease ; Pressure Diuresis ; ATP release ; Chronic Kidney Disease ; Nitric Oxide ; Angiotensin II ; tubuloglomerular feedback ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 141
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; biorefinery ; polyphenols ; dynamic simulation ; Fucus distichus subsp. evanescens ; seaweeds ; phytochemicals ; Bifurcaria bifurcata ; Fucus vesiculosus ; kidney ; complex polysaccharides ; identification ; secondary metabolites ; phlorotannin ; cholinesterases ; eckol ; skin aging ; clinical trials ; dieckol ; fucoxanthin ; age-related macular degeneration ; photo-protection ; phytol ; Alzheimer’s disease ; fucosterol ; bone health ; nutraceutical ; papillomavirus ; red seaweed ; extraction ; osteoporosis ; fucoidan ; marine algae ; chemo-preventive agent ; ischemia-reperfusion injury ; hyperpigmentation ; bone metabolism ; bioactives ; macroalgae ; beta-secretase ; laurinterol ; prebiotics ; dietary fibre ; NMR spectroscopy ; health effects ; bromophenols ; beta-amyloid aggregation ; kahalalide F ; Padina pavonica ; carotenoids ; insulin glycation ; skincare ; mushroom tyrosinase ; polyunsaturated fatty acids ; fatty acid ; in vivo studies ; apoptosis ; algae ; biological activities ; Symphyocladia latiuscula ; Fucus serratus ; mass spectrometry ; Laminaria digitata ; high-speed counter-current chromatography ; isolation and purification ; K14HPV16 ; amyloid-? aggregation ; VEGF ; melanin ; Laurencia ; seaweed ; organotypic culture ; Saccharina latissima ; ex vivo ; genotoxicity assay ; gut microbiota ; phlorotannins ; eckmaxol ; high value applications ; Ecklonia maxima ; B16F10 ; neuroprotection ; linear diterpenes ; antitumoral ; Ecklonia cava ; cancer ; breast cancer explants ; osteosarcoma ; oxidative stress ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 142
    Publication Date: 2024-04-05
    Description: The Volume II is entitled “Neurostimulation and pharmacological approaches”. This volume describes augmentation approaches, where improvements in brain functions are achieved by modulation of brain circuits with electrical or optical stimulation, or pharmacological agents. Activation of brain circuits with electrical currents is a conventional approach that includes such methods as (i) intracortical microstimulation (ICMS), (ii) transcranial direct current stimulation (tDCS), and (iii) transcranial magnetic stimulation (TMS). tDCS and TMS are often regarded as noninvasive methods. Yet, they may induce long-lasting plastic changes in the brain. This is why some authors consider the term “noninvasive” misleading when used to describe these and other techniques, such as stimulation with transcranial lasers. The volume further discusses the potential of neurostimulation as a research tool in the studies of perception, cognition and behavior. Additionally, a notion is expressed that brain augmentation with stimulation cannot be described as a net zero sum proposition, where brain resources are reallocated in such a way that gains in one function are balanced by costs elsewhere. In recent years, optogenetic methods have received an increased attention, and several articles in Volume II cover different aspects of this technique. While new optogenetic methods are being developed, the classical electrical stimulation has already been utilized in many clinically relevant applications, like the vestibular implant and tactile neuroprosthesis that utilizes ICMS. As a peculiar usage of neurostimulation and pharmacological methods, Volume II includes several articles on augmented memory. Memory prostheses are a popular recent development in the stimulation-based BMIs. For example, in a hippocampal memory prosthesis, memory content is extracted from hippocampal activity using a multiple-input, multiple-output non-linear dynamical model. As to the pharmacological approaches to augmenting memory and cognition, the pros and cons of using nootropic drugs are discussed.
    Keywords: RC321-571 ; Q1-390 ; microcircuits ; Brain machine interface (BMI) ; nootropics ; tDCStranscranial direct current stimulation ; neural networks ; neuroprosthesis ; TMS ; implants ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 143
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    Presses Universitaires de Bordeaux
    Publication Date: 2023-12-20
    Description: Par sa maîtrise parfaite des traitements d'images, par sa connaissance des techniques de laboratoire les plus modernes, et surtout par son approche méthodique du terrain, l'auteur de cet ouvrage apporte certainement la meilleure étude française du milieu naturel yucatèque, avec des informations inédites sur la spéléologie et la géomorphologie karstique tropicale, le volcanisme régional ou encore les variations du niveau de la mer dans la région caraïbe.
    Keywords: Q1-390 ; géographie ; société ; climat ; géosystème ; système d'érosion ; environnement ; karst ; géomorphologie ; érosion ; milieu tropical ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: French
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  • 144
    Publication Date: 2024-04-05
    Description: Despite increased knowledge, and more sophisticated experimental and modeling approaches, fundamental questions remain about how electricity can interact with ongoing brain function in information processing or as a medical intervention. Specifically, what biophysical and network mechanisms allow for weak electric fields to strongly influence neuronal activity and function? How can strong and weak fields induce meaningful changes in CNS function? How do abnormal endogenous electric fields contribute to pathophysiology? Topics included in the review range from the role of field effects in cortical oscillations, transcranial electrical stimulation, deep brain stimulation, modeling of field effects, and the role of field effects in neurological diseases such as epilepsy, hemifacial spasm, trigeminal neuralgia, and multiple sclerosis.
    Keywords: RC321-571 ; Q1-390 ; Transcranial Magnetic Stimulation ; ephaptic ; Systems neuroscience ; brain oscillation ; transcranial direct current stimulation (tDCS) ; stimulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 145
    Publication Date: 2024-04-05
    Description: The superordinate division of emotions is distributed along a bipolar dimension of affective valence, from approaching rewarding situations to avoiding punitive situations. Avoiding and approaching behaviors determine the disposition to the primary emotions of fear and attachment and the behavioral responses to the environmental stimuli of danger, novelty and reward. Approach or avoidance behaviors are associated with the brain pathways controlling cognitive and attentional function, reward sensitivity and emotional expression, involving prefrontal cortex, amygdala, striatum and cerebellum. Individual differences in approach and avoidance behavior might be modulated by normal variance in the level of functioning of different neurotransmitter systems, such as dopaminergic, serotoninergic, noradrenergic and endocannabinoid systems as well as many peptides such as corticotropin releasing hormone. These substances act at various central target areas to increase intensity of appetitive or defensive motivation. Physiologically, personality temperaments of approach and avoidance are viewed as instigators of propensity. They produce immediate affective, cognitive and behavioral inclinations in response to stimuli and orient individuals across domains and situations in a consistent fashion. Although the action undoubtedly emerges directly from these temperamental proclivities, ultimate behavioral outcomes are often a function of the integration among goal pursuit, self-regulation, and temperament trait. Defective coping strategies to aversive or rewarding stimuli characterize the patho-physiology of anxiety- and stress-related disorders or compulsive and addiction behaviors, respectively. Individuals with neuropsychiatric symptoms such as depression, suicidal behavior, bipolar mania, schizophrenia, substance use disorders, pathological gambling and anxiety disorders have scores which fall at the extreme tails of the normal distribution for a specific temperamental trait. The present Research Topic on the individual differences in emotional and motivational processing emphasizes the link between neuronal pattern and behavioral expression. The Topic includes experimental and clinical researches addressing the individual differences related to approach and avoidance and their behavioral characterization, structural and neurochemical profiles, synaptic connections, and receptor expressions. Studies are organized in a framework that puts in evidence the phenotypic expression and neurobiological patterns characterizing the individual differences and their biological variance.
    Keywords: RC321-571 ; Q1-390 ; Fear System ; stress ; reinforcement sensitivity theory ; Anxiety ; motivational disorders ; personality traits ; rewarding and aversive stimuli ; affective and emotional neuroscience ; dopaminergic and endocannabinoid systems ; resilience ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 146
    Publication Date: 2024-04-05
    Description: The field of autonomic neuroscience research concentrates on those neural pathways and processes that ultimately modulate parasympathetic and sympathetic output to alter peripheral organ function. In the following ebook, laboratories from across the field have contributed reviews and original research to summarize current views on the role of the brain in tuning peripheral organ performance to regulate body temperature, glucose homeostasis and blood pressure.
    Keywords: RC321-571 ; Q1-390 ; Hypertension ; Nucleus Accumbens ; Thermogenesis ; vagal afferents ; TRPV Cation Channels ; Leptin ; Sympathetic Nervous System ; Parasympathetic Nervous System ; Glucose ; Hypoglycemia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 147
    Publication Date: 2024-04-05
    Description: The ultimate goal of functional brain imaging is to provide optimal estimates of the neural signals flowing through the long-range and local pathways mediating all behavioral performance and conscious experience. In functional MRI (Magnetic Resonance Imaging), despite its impressive spatial resolution, this goal has been somewhat undermined by the fact that the fMRI response is essentially a blood-oxygenation level dependent (BOLD) signal that only indirectly reflects the nearby neural activity. The vast majority of fMRI studies restrict themselves to describing the details of these BOLD signals and deriving non-quantitative inferences about their implications for the underlying neural activity. This Frontiers Research Topic welcomed empirical and theoretical contributions that focus on the explicit relationship of non-invasive brain imaging signals to the causative neural activity. The articles presented within this resulting eBook aim to both highlight the importance and improve the non-invasive estimation of neural signals in the human brain. To achieve this aim, the following issues are targeted: (1) The spatial limitations of source localization when using MEG/EEG. (2) The coupling of the BOLD signal to neural activity. Articles discuss how animal studies are fundamental in increasing our understanding of BOLD fMRI signals, analyze how non-neuronal cell types may contribute to the modulation of cerebral blood flow, and use modeling to improve our understanding of how local field potentials are linked to the BOLD signal. (3) The contribution of excitatory and inhibitory neuronal activity to the BOLD signal. (4) Assessment of neural connectivity through the use of resting state data, computational modeling and functional Diffusion Tensor Imaging (fDTI) approaches.
    Keywords: RC321-571 ; Q1-390 ; Neuroimaging ; functional MRI ; human brain ; connectivity ; EEG ; DTI ; neurovascular ; neural signal estimation ; BOLD ; MEG ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 148
    Publication Date: 2022-01-31
    Description: Biodegradation mediated by indigenous microbial communities is the ultimate fate of the majority of oil hydrocarbon that enters the marine environment. The aim of this Research Topic is to highlight recent advances in our knowledge of the pathways and controls of microbially-catalyzed hydrocarbon degradation in marine ecosystems, with emphasis on the response of microbial communities to the Deepwater Horizon oil spill in the Gulf of Mexico. In this Research Topic, we encouraged original research and reviews on the ecology of hydrocarbon-degrading bacteria, the rates and mechanisms of biodegradation, and the bioremediation of discharged oil under situ as well as near in situ conditions.
    Keywords: GC1-1581 ; QR1-502 ; Q1-390 ; Biodegradation ; Metagenomics ; oil spill ; metatran ; bacterioplankton ; Bacteria ; Gulf of Mexico ; microbial communities ; hydrocarbon ; Deepwater Horizon
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  • 149
    Publication Date: 2024-04-05
    Description: Sigmund Freud was a trained neuroanatomist and wrote his first psychoanalytical theory in neuroscientific terms. Throughout his life, he maintained the belief that at some distant day in the future, all psychoanalytic processes could be tied to a neural basis: “We must recollect that all of our provisional ideas in psychology will presumably one day be based on an organic substructure” (Freud 1914, On Narcissism: An Introduction). Fundamental Freudian concepts reveal their foundation in the physiological science of his time, most importantly among them the concept of libidinous energy and the homeostatic “principle of constancy”. However, the subsequent history of psychoanalysis and neuroscience was mainly characterized by mutual ignorance or even opposition; many scientists accused psychoanalytic viewpoints not to be scientifically testable, and many psychoanalysts claimed that their theories did not need empirical support outside of the therapeutic situation. On this historical background, it may appear surprising that the recent years have seen an increasing interest in re-connecting psychoanalysis and neuroscience in various ways: By studying psychodynamic consequences of brain lesions in neurological patients, by investigating how psychoanalytic therapy affects brain structure and function, or even by operationalizing psychoanalytic concepts in well-controlled experiments and exploring their neural correlates. These empirical studies are accompanied by theoretical work on the philosophical status of the “neuropsychoanalytic” endeavour. In this volume, we attempt to provide a state-of-the-art overview of this new exciting field. All types of submissions are welcome, including research in patient populations, healthy human participants and animals, review articles on some empirical or theoretical aspect, and of course also critical accounts of the new field. Despite this welcome variability, we would like to suggest that all contributions attempt to address one (or both) of two main questions, which should motivate the connection between psychoanalysis and neuroscience and that in our opinion still remain exigent: First, from the neuroscientific side, why should researchers in the neurosciences address psychoanalytic ideas, and what is (or will be) the impact of this connection on current neuroscientific theories? Second, from the psychoanalytic side, why should psychoanalysts care about neuroscientific studies, and (how) can current psychoanalytical theory and practice benefit from their results? Of course, contributors are free to provide a critical viewpoint on these two questions as well.
    Keywords: RC321-571 ; BF1-990 ; Q1-390 ; Neuroscience ; Neuropsychoanalysis ; psychodynamic psychotherapy ; psychoanalysis ; neuroimaging ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 150
    Publication Date: 2022-01-31
    Description: This research topic highlights the most recent accomplishments of a Scientific Committee on Oceanic Research (SCOR) Working Group, SCOR WG 139: Organic Ligands - A Key Control on Trace Metal Biogeochemistry in the Ocean.
    Keywords: GC1-1581 ; Q1-390 ; trace metals ; ocean chemistry ; organic ligands ; seawater ; chemical speciation
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  • 151
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Beer is a beverage with more than 8000 years of history, and the process of brewing has not changed much over the centuries. However, important technical advances have allowed us to produce beer in a more sophisticated and efficient way. The proliferation of specialty hop varieties has been behind the popularity of craft beers seen in the past few years around the world. Craft brewers interpret historic beer with unique styles. Craft beers are undergoing an unprecedented period of growth, and more than 150 beer styles are currently recognized. This Special Issue, Brewing and Craft Beer, comprises nine different works by researchers from five continents (North America, South America, Europe, Africa, and Oceania). This Special Issue reflects thus a broad perspective on the most important questions that concern the researchers in different parts of the world.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; polyphenols ; n/a ; nutrient ; audible sound ; wet milling ; brewing technology ; robotics ; fast-screening ; lactose ; image analysis ; bottle refermentation ; beer aging ; sensory attributes ; brewing ; automation ; bitterness ; stout beer ; beer ; craft beer ; foamability ; Safrari ; adjuncts ; fermentation rate ; barley milling ; preference ; germ ; beer wort ; machine learning ; carbonation ; quality ; FAN ; granulometry ; sensory evaluation ; coffee ; beer acceptability ; computer vision ; fermentation ; economic contribution analysis ; short-chain fatty acids ; local value chain ; AEDA ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 152
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Autophagy (also known as macroautophagy) is an evolutionarily conserved process by which cytoplasmic components are nonselectively enclosed within a double-membrane vesicle known as the autophagosome and delivered to the vacuole for degradation of toxic components and recycling of needed nutrients. This catabolic process is required for the adequate adaptation and response of the cell, and correspondingly the whole organism, to different types of stress including nutrient starvation or oxidative damage. Autophagy has been extensively investigated in yeasts and mammals but the identification of autophagy-related (ATG) genes in plant and algal genomes together with the characterization of autophagy-deficient mutants in plants have revealed that this process is structurally and functionally conserved in photosynthetic eukaryotes. Recent studies have demonstrated that autophagy is active at a basal level under normal growth in plants and is upregulated during senescence and in response to nutrient limitation, oxidative stress, salt and drought conditions and pathogen attack. Autophagy was initially considered as a non-selective pathway, but numerous observations mainly obtained in yeasts revealed that autophagy can also selectively eliminate specific proteins, protein complexes and organelles. Interestingly, several types of selective autophagy appear to be also conserved in plants, and the degradation of protein aggregates through specific adaptors or the delivery of chloroplast material to the vacuole via autophagy has been reported. This research topic aims to gather recent progress on different aspects of autophagy in plants and algae. We welcome all types of articles including original research, methods, opinions and reviews that provide new insights about the autophagy process and its regulation.
    Keywords: QK1-989 ; Q1-390 ; Lipid degradation ; selective autophagy ; pexophagy ; algae ; Plants ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
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  • 153
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This book is a collection of 13 innovative papers describing the state of the art and the future perspectives in solid-phase extraction covering several analytical fields prior to the use of gas or liquid chromatographic analysis. New sorptive materials are presented including carbon nanohorn suprastructures on paper support, melamine sponge functionalized with urea–formaldehyde co-oligomers, chiral metal–organic frameworks, UiO-66-based metal–organic frameworks, and fabric phase sorptive media for various applications. Solid-phase extraction can be applied in several formats aside from the conventional cartridges or mini-column approach, e.g., online solid-phase extraction, dispersive solid-phase microextraction, and in-syringe micro-solid-phase extraction can be very helpful for analyte pre-concentration and sample clean-up. Polycyclic musks in aqueous samples, 8-Nitroguanine in DNA by chemical derivatization antibacterial diterpenes from the roots of salvia prattii, perfluoroalkyl substances (PFASs) in aater samples by bamboo charcoal-based SPE, parabens in environmental water samples, benzotriazoles as environmental pollutants, organochlorine pesticide residues in various fruit juices and water samples and synthetic peptide purification are among the applications cited in this collection. All these outstanding contributions highlight the necessity of this analytical step, present the advantages and disadvantages of each method and focus on the green analytical chemistry guidelines that have to be fulfilled in current analytical practices.
    Keywords: QD1-999 ; Q1-390 ; method validation ; nitrated DNA lesion ; benzotriazoles ; microextraction ; LC-MS/MS ; perfluoroalkyl acids ; antibacterial diterpenes ; in-house loaded SPE ; isotope-dilution ; polycyclic musks ; wastewater ; peptide ; HPLC-DAD ; chiral compounds ; derivatization ; extraction ; water ; enantiomeric excess ; sample preparation ; metal-organic frameworks ; solid-phase extraction ; FPSE ; melamine sponge ; preparative high-performance liquid chromatography ; GC–MS/MS ; solid phase peptide synthesis ; HPLC-PDA ; Salvia prattii ; in-syringe micro solid-phase extraction ; organochlorine pesticides ; hydrophilic solid-phase extraction ; response surface methodology ; IBD ; graphene ; sorptive phase ; paper ; liquid chromatography–tandem mass spectrometry ; carbon nanohorns ; gradient elution ; peroxynitrite ; bamboo charcoal ; gas chromatography-mass spectrometry ; environmental samples ; parabens ; solid phase extraction (SPE) ; preparative purification ; antidepressants ; online solid-phase extraction ; organic pollutants ; urea-formaldehyde co-oligomers ; personal care products ; dispersive solid-phase extraction ; fabric phase sorptive extraction ; analyte partitioning ; thema EDItEUR::P Mathematics and Science::PN Chemistry
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  • 154
    Publication Date: 2024-04-05
    Description: The aim of this Research Topic for Frontiers in Psychology under the section of Cognitive Science and Frontiers in Neurorobotics is to present state-of-the-art research, whether theoretical, empirical, or computational investigations, on open-ended development driven by intrinsic motivations. The topic will address questions such as: How do motivations drive learning? How are complex skills built up from a foundation of simpler competencies? What are the neural and computational bases for intrinsically motivated learning? What is the contribution of intrinsic motivations to wider cognition? Autonomous development and lifelong open-ended learning are hallmarks of intelligence. Higher mammals, and especially humans, engage in activities that do not appear to directly serve the goals of survival, reproduction, or material advantage. Rather, a large part of their activity is intrinsically motivated - behavior driven by curiosity, play, interest in novel stimuli and surprising events, autonomous goal-setting, and the pleasure of acquiring new competencies. This allows the cumulative acquisition of knowledge and skills that can later be used to accomplish fitness-enhancing goals. Intrinsic motivations continue during adulthood, and in humans artistic creativity, scientific discovery, and subjective well-being owe much to them. The study of intrinsically motivated behavior has a long history in psychological and ethological research, which is now being reinvigorated by perspectives from neuroscience, artificial intelligence and computer science. For example, recent neuroscientific research is discovering how neuromodulators like dopamine and noradrenaline relate not only to extrinsic rewards but also to novel and surprising events, how brain areas such as the superior colliculus and the hippocampus are involved in the perception and processing of events, novel stimuli, and novel associations of stimuli, and how violations of predictions and expectations influence learning and motivation. Computational approaches are characterizing the space of possible reinforcement learning algorithms and their augmentation by intrinsic reinforcements of different kinds. Research in robotics and machine learning is yielding systems with increasing autonomy and capacity for self-improvement: artificial systems with motivations that are similar to those of real organisms and support prolonged autonomous learning. Computational research on intrinsic motivation is being complemented by, and closely interacting with, research that aims to build hierarchical architectures capable of acquiring, storing, and exploiting the knowledge and skills acquired through intrinsically motivated learning. Now is an important moment in the study of intrinsically motivated open-ended development, requiring contributions and integration across a large number of fields within the cognitive sciences. This Research Topic aims to contribute to this effort by welcoming papers carried out with ethological, psychological, neuroscientific and computational approaches, as well as research that cuts across disciplines and approaches.
    Keywords: RC321-571 ; BF1-990 ; Q1-390 ; computational models ; intrinsic motivations ; autonomous robotics ; novelty and surprise ; review ; cumulative learning and development ; brain and behavior ; reinforcement learning ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 155
    Publication Date: 2024-03-29
    Description: One significant area of research in the multifaceted field of bilingualism over the past two decades has been the demonstration, validation, and account of the so-called ‘bilingual advantage’. This refers to the hypothesis that bilingual speakers have advanced abilities in executive functions and other domains of human cognition. Such cognitive benefits of bilingualism have an impact on the processing mechanisms active during language acquisition in a way that results in language variation. Within bilingual populations, the notion of language proximity (or linguistic distance) is also of key importance for deriving variation. In addition, sociolinguistic factors can invest the process of language development and its outcome with an additional layer of complexity, such as schooling, language, dominance, competing motivations, or the emergence of mesolectal varieties, which blur the boundaries of grammatical variants. This is particularly relevant for diglossic speech communities—bilectal, bidialectal, or bivarietal speakers. The defined goal of the present Research Topic is to address whether the bilingual advantage extends to such speakers as well. Thus, ‘Linguistic and Cognitive Profiles for Speakers of Linguistically Proximal Languages and Varieties’ become an important matter within ‘Developmental, Modal, and Pathological Variation’.
    Keywords: BF1-990 ; P87-96 ; Q1-390 ; (a)typical development ; Proximity ; executive functions ; impaired language ; Language variation ; multilectalism ; cognitive advantage ; Varieties ; bilingualism ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 156
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron–sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; regeneration ; posttranslational modification ; H2O2 ; chilling stress ; thioredoxin reductase ; X-ray crystallography ; photosynthesis ; Chlamydomonas reinhardtii ; protein ; monodehydroascorbate reductase ; methionine sulfoxide ; cysteine reactivity ; symbiosis ; plant ; MALDI-TOF mass spectrometry ; thioredoxins ; redox homeostasis ; methionine sulfoxide reductases ; redox ; redox signalling ; chloroplast ; protein-protein recognition ; cyanobacteria ; specificity ; wheat ; methanoarchaea ; stress ; redox regulation ; dough rheology ; methionine sulfoxide reductase ; electrostatic surface ; Calvin cycle ; ALAD ; metazoan ; Arabidopsis thaliana ; baking ; cold temperature ; macromolecular crystallography ; protein oxidation ; function ; methionine oxidation ; development ; iron–sulfur cluster ; tetrapyrrole biosynthesis ; legume plant ; glutathionylation ; Calvin-Benson cycle ; adult stem cells ; carbon fixation ; plastidial ; methionine ; redox active site ; ROS ; water stress ; NADPH ; repair ; physiological function ; signaling ; thioredoxin ; antioxidants ; glutathione ; glutaredoxin ; flavin ; Isocitrate dehydrogenase ; thiol redox network ; ageing ; disulfide ; mitochondria ; chlorophyll ; proteomic ; cysteine alkylation ; ferredoxin-thioredoxin reductase ; SAXS ; regulation ; oxidized protein repair ; ascorbate ; redox control ; nitrosylation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 157
    Publication Date: 2024-04-05
    Description: Phage biology is one of the most significant and fundamental aspects of biological research and is often used as a platform for model studies relating to more complex biological entities. For this reason, phage biology has enjoyed focused attention and significant advances have been made in the areas of phage genomics, transcriptomics and the development and characterisation of phage-resistance mechanisms. In recent years, considerable research has been performed to increase our understanding of the interactions of these phages with their hosts using genomic, biochemical and structural approaches. Such multidisciplinary approaches are core to developing a full understanding of the processes that govern phage infection, information that may be harnessed to develop anti-phage strategies that may be applied in food fermentations or applied in a positive sense in phage therapy applications. The co-evolutionary processes of these phages and their hosts have also been a considerable focus of research in recent years. Such data has promoted a deeper understanding of the means by which these phages attach to and infect their hosts and permitted the development of effective anti-phage strategies. Furthermore, the presence and activity of host-encoded phage-resistance systems that operate at various stages of the phage cycle and the potential for the application of such systems consolidates the value of research in this area. Conversely, phages and their components have been applied as therapeutic agents against a number of pathogens including, among others, Clostridium difficile, Lactococcus garviae, Mycobacterium spp., Listeria spp. and the possibilities and limitations of these systems will be explored in this topic. Additionally, phage therapeutic approaches have been applied to the prevention of development of food spoilage organisms in the brewing and beverage sectors and exhonorate the positive applications of phages in the industrial setting. This research topic is aimed to address the most current issues as well as the most recent advances in the research of phages infecting Gram-positive bacteria covering areas such as phages in food fermentations, their impact in industry, phage ecology, genomics, evolution, structural analysis, phage-host interactions and the application of phages and components thereof as therapeutic agents against human and animal pathogens.
    Keywords: QR1-502 ; Q1-390 ; Lactic acid bacteria ; food fermentation ; phage therapy ; Phage-host interactions ; phages ; dairy industry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 158
    Publication Date: 2024-04-05
    Description: The huge volume of multi-modal neuroimaging data across different neuroscience communities has posed a daunting challenge to traditional methods of data sharing, data archiving, data processing and data analysis. Neuroinformatics plays a crucial role in creating advanced methodologies and tools for the handling of varied and heterogeneous datasets in order to better understand the structure and function of the brain. These tools and methodologies not only enhance data collection, analysis, integration, interpretation, modeling, and dissemination of data, but also promote data sharing and collaboration. This Neuroinformatics Research Topic aims to summarize the state-of-art of the current achievements and explores the directions for the future generation of neuroinformatics infrastructure. The publications present solutions for data archiving, data processing and workflow, data mining, and system integration methodologies. Some of the systems presented are large in scale, geographically distributed, and already have a well-established user community. Some discuss opportunities and methodologies that facilitate large-scale parallel data processing tasks under a heterogeneous computational environment. We wish to stimulate on-going discussions at the level of the neuroinformatics infrastructure including the common challenges, new technologies of maximum benefit, key features of next generation infrastructure, etc. We have asked leading research groups from different research areas of neuroscience/neuroimaging to provide their thoughts on the development of a state of the art and highly-efficient neuroinformatics infrastructure. Such discussions will inspire and help guide the development of a state of the art, highly-efficient neuroinformatics infrastructure.
    Keywords: RC321-571 ; Q1-390 ; Neuroimaging ; database ; neuroinformatics ; workflow ; infrastructure ; high-throughput ; data processing ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 159
    Publication Date: 2024-04-05
    Description: Neuroimmunology is a rapidly growing emerging field at which two old sciences have converged to integrate two different types of responses into a single coherent response involving the coordinated action of both systems, neural and immune. During long time it was thought that both systems worked separately and in divergent pathways. The brain was considered an immunoprivileged site and the immune organs were deemed as independent of any neural influence and also of nervous innervation. Time has gone and has proven that the borders between both systems were merely artificial. Since the beginning of Neuroimmunology in the 1980s much work has been done to elucidate the gates and fences in neuro-immune interactions. Brain was shown to be under the continuous surveillance of the immune system, even under basal physiological conditions in the absence of any pathology. Likely, it was found a profuse nervous innervation of lymphoid organs and even of single immune cells. Gates for direct neural immune communication were found both centrally and peripherally. Centrally, the gates, but also the fences, were situated at the brain barriers, the blood-brain barrier and the blood-cerebrospinal fluid barrier, and at the circunventricular organs. Peripherally, the fences constituted the apparent diverse nature of molecules involved in neural and immune signaling; however, time proved that both system were capable of producing the same signaling molecules and also systematically responded to the molecules released by the other system. Therefore, the gates were open for direct neural-immune communication at the peripheral level. This Research Topic aimed to include original reports, reviews and technical reports regarding the description of the gates and fences in neural immune interactions. We intended to provide an extensive view of the mechanisms governing central and peripheral neural-immune interactions, and the role of the borders, the blood-neural barriers, in the regulation of the neural-immune communication.
    Keywords: RC321-571 ; Q1-390 ; Brain ; Nervous System ; Immune System ; Cytokines ; endocrine sytem ; Hormones ; Neuro-imuno-endocrine ; brain barriers ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 160
    Publication Date: 2024-03-31
    Description: The Frontiers Research Topic entitled "Neuromuscular Training and Adaptations in Youth Athletes" contains one editorial and 22 articles in the form of original work, narrative and systematic reviews and meta-analyses. From a performance and health-related standpoint, neuromuscular training stimulates young athletes' physical development and it builds a strong foundation for later success as an elite athlete. The 22 articles provide current scientific knowledge on the effectiveness of neuromuscular training in young athletes.
    Keywords: QP1-981 ; Q1-390 ; strength training ; resistance training ; performance ; physical fitness ; adolescent athletes ; health ; plyometrics ; child athletes ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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  • 161
    Publication Date: 2024-03-29
    Description: In many areas of human life, people perform in teams. These teams’ performances depend, at least partly, on team members’ abilities to coordinate their contributions effectively. This includes the making of decisions and the regulation of behavior in reference to the framework provided by the social group- and task-context. Given the high relevance of a deepened and integrated understanding about the mechanisms underlying coordinated team behavior, the aim of this research topic is to provide a platform for different theoretical and methodological approaches to researching and understanding coordinated team behavior in different task contexts. The articles published in this edition offer a multifaceted insight into current work on the topic.
    Keywords: BF1-990 ; Q1-390 ; performance ; team work ; collaboration ; decision making ; team sports ; group ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 162
    Publication Date: 2024-04-01
    Description: For decades we have known that the overgrowth, hardening and scarring of tissues (so-called fibrosis) represents the final common pathway and best histological predictor of disease progression in most organs. Fibrosis is the culmination of both excess extracellular matrix deposition due to ongoing or severe injury, and a failure to regenerate. An inadequate wound repair process ultimately results in organ failure through a loss of function, and is therefore a major cause of morbidity and mortality in disease affecting both multiple and individual organs.Whilst the pathology of fibrosis and its significance are well understood, until recently we have known little about its molecular regulation. Current therapies are often indirect and non-specific, and only slow progression by a matter of months. The recent identification of novel therapeutic targets, and the development of new treatment strategies based on them, offers the exciting prospect of more efficacious therapies to treat this debilitating disorder.This Research Topic therefore compromises several up-to-date mini-reviews on currently known and emerging therapeutic targets for fibrosis including: the Transforming Growth Factor (TGF)-family; epigenetic factors; Angiotensin II type 2 (AT2) receptors; mineralocorticoid receptors; adenosine receptors; caveolins; and the sphingosine kinase/sphingosine 1-phosphate and notch signaling pathways. In each case, mechanistic insights into how each of these factors contribute to regulating fibrosis progression are described, along with how they can be targeted (by existing drugs, small molecules or other mimetics) to prevent and/or reverse fibrosis and its contribution to tissue dysfunction and failure. Two additional reviews will discuss various anti-fibrotic therapies that have demonstrated efficacy at the experimental level, but are not yet clinically approved; and the therapeutic potential vs limitations of stem cell-based therapies for reducing fibrosis while facilitating tissue repair. Finally, this Research Topic concludes with a clinical perspective of various anti-fibrotic therapies for cardiovascular disease (CVD), outlining limitations of currently used therapies, the pipeline of anti-fibrotics for CVD and why so many anti-fibrotic drugs have failed at the clinical level.
    Keywords: RM1-950 ; Q1-390 ; treatment strategies ; Fibrosis ; pharmacology ; collagen ; fibrogenesis ; therapeutic targets ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
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  • 163
    Publication Date: 2023-12-20
    Description: The book deals with novel aspects and perspectives in functionally graded materials (FGMs), which are advanced engineering materials designed for a specific performance or function with spatial gradation in structure and/or composition. The contributions mainly focus on numerical simulations of mechanical properties and the behavior of FGMs and FGM structures. Several advancements in numerical simulations that are particularly useful for investigations on FGMs have been proposed and demonstrated in this Special Issue. Such proposed approaches provide incisive methods to explore and predict the mechanical and structural characteristics of FGMs subjected to thermoelectromechanical loadings under various boundary and environmental conditions. The contributions have resulted in enhanced activity regarding the prediction of FGM properties and global structural responses, which are of great importance when considering the potential applications of FGM structures. Furthermore, the presented scientific scope is, in some way, an answer to the continuous demand for FGM structures, and opens new perspectives for their practical use.
    Keywords: QA1-939 ; Q1-390 ; power-law distribution ; evanescent wave ; flow theory of plasticity ; free vibration characteristics ; neural networks ; geometrically nonlinear analysis ; finite element method ; stress concentration factor ; inhomogeneous composite materials ; circular plate ; porous materials ; minimum module approximation method ; ANFIS ; electroelastic solution ; functionally graded piezoelectric materials ; Love wave ; polynomial approach ; stepped FG paraboloidal shell ; material design ; damping coefficient ; spring stiffness technique ; Lamb wave ; pure bending ; general edge conditions ; residual stress ; graded finite elements ; large strain ; non-linear buckling analysis ; orthogonal stiffener ; combined mechanical loads ; functionally graded piezoelectric-piezomagnetic material ; functionally graded beams ; attenuation ; failure and damage ; analytical solution ; functionally graded materials ; elastoplastic analysis ; elastic foundation ; hollow disc ; different moduli in tension and compression ; external pressure ; functional graded saturated material ; bimodulus ; fuzzy logic ; truncated conical sandwich shell ; quadratic solid–shell elements ; functionally graded viscoelastic material ; finite element analysis ; residual strain ; neutral layer ; elliptical hole ; thin structures ; functionally graded plate ; inhomogeneity ; clustering ; metal foam core layer ; robotics and contact wear ; dispersion ; high order shear deformation theory ; finite elements ; bic Book Industry Communication::P Mathematics & science
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  • 164
    Publication Date: 2022-01-31
    Description: An important amount of research effort in psychology and neuroscience over the past decades has focused on the problem of social cognition. This problem is understood as how we figure out other minds, relying only on indirect manifestations of other people's intentional states, which are assumed to be hidden, private and internal. Research on this question has mostly investigated how individual cognitive mechanisms achieve this task. A shift in the internalist assumptions regarding intentional states has expanded the research focus with hypotheses that explore the role of interactive phenomena and interpersonal histories and their implications for understanding individual cognitive processes. This interactive expansion of the conceptual and methodological toolkit for investigating social cognition, we now propose, can be followed by an expansion into wider and deeply-related research questions, beyond (but including) that of social cognition narrowly construed. Our social lives are populated by different kinds of cognitive and affective phenomena that are related to but not exhausted by the question of how we figure out other minds. These phenomena include acting and perceiving together, verbal and non-verbal engagement, experiences of (dis-)connection, management of relations in a group, joint meaning-making, intimacy, trust, conflict, negotiation, asymmetric relations, material mediation of social interaction, collective action, contextual engagement with socio-cultural norms, structures and roles, etc. These phenomena are often characterized by a strong participation by the cognitive agent in contrast with the spectatorial stance typical of social cognition research. We use the broader notion of embodied intersubjectivity to refer to this wider set of phenomena. This Research Topic aims to investigate relations between these different issues, to help lay strong foundations for a science of intersubjectivity – the social mind writ large. To contribute to this goal, we encouraged contributions in psychology, neuroscience, psychopathology, philosophy, and cognitive science that address this wider scope of intersubjectivity by extending the range of explanatory factors from purely individual to interactive, from observational to participatory.
    Keywords: BF1-990 ; Q1-390 ; participatory sense making ; social affordances ; Emergence of culture ; Dynamical Systems Theory ; social interaction ; Second-person methods ; Psychopathology ; Affect ; languaging
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  • 165
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    SciELO Books - EDUFBA
    Publication Date: 2023-12-20
    Description: Na cidade contemporânea os lugares da natureza estão previamente selecionados e mercantilizados. O livro O Direito à Natureza na Cidade, de autoria do Professor Doutor Wendel Henrique, busca reconstruir as relações entre a cidade e a natureza, através da análise das representações, ideologias e práticas ao longo da história. O livro destaca o papel do mercado imobiliário na apropriação e produção da natureza na cidade, bem como no próprio design dessa natureza, através de padrões predefinidos e difundidos em escala global. Os elementos empíricos foram desenvolvidos através de pesquisas realizadas nas cidades de São Paulo, Florianópolis e Salvador. A obra se constitui no entendimento do uso da natureza como forma de emancipação coletiva, superando as visões correntes pautadas na apropriação da natureza para garantia da satisfação pessoal.
    Keywords: Q1-390 ; SCIENCE ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: Portuguese
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  • 166
    Publication Date: 2024-04-05
    Description: Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; high-fat high-carbohydrate diet ; toxicity ; oxysterol ; n/a ; squalene cyclase ; sterol content ; sterolomics ; Polystichum ; Smith-Lemli-Opitz syndrome ; antifungals ; alkaloid ; cycloartenol synthase ; degeneration ; phytosterol ; Rhizopus arrhizus ; fibroblasts ; pod-blast ; fern ; cholesterol ; cytotoxic activity ; N-methylpiperidine. reductive deamination ; genetic disease ; isoprenoid ; steroid ; atherosclerosis ; granatane ; antioxidant ; wound healing ; development ; enzyme-assisted derivatization ; maturity ; terpene ; keratinocytes ; C4-demethylation complex (C4DMC) ; ?-sitosterol ; mesocarp ; sterol biosynthesis ; mechanism-based inactivators ; Mucorales ; gas chromatography-mass spectrometry (GC-MS) ; Girard reagent ; ROS ; sterol pattern ; N-methylcadaverine ; ?-tocopherol ; electrospray ionization-mass spectrometry ; human African trypanosomiasis ; HUVECs ; lipidomics ; campesterol ; triterpene ; oxyphytosterol ; leishmania ; Chagas disease ; LOX-1 ; sterol C24-methyltransferase ; antifungal effectivity ; ergosterol biosynthesis ; hormone ; glucose homeostasis ; retina ; solanaceae ; cholestanoic acid ; algal sterols ; cell migration ; withanolides ; insulin resistance ; Zingiber officinale ; posaconazole ; synthesis ; pre-diabetes ; pharmacognosy ; sterol ; 4-methylsterol ; oleanolic acid ; antiparasitic drugs ; lupeol ; oilseed ; aurelianolides ; divalent metal co-factor ligation ; bile alcohol ; phytosterols ; azoles ; infectious disease ; gingerols ; UV-radiation ; oil bodies ; ZnO ; sterol 14?-demethylase ; stigmasterol ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 167
    Publication Date: 2024-03-29
    Description: Attachment theory, assessment and research offers a broad, far-reaching view of human functioning, and it can enrich a psychologist's understanding of subjects and their relational adjustment, both in clinical and non-clinical settings. Ongoing research in attachment has led to a number of individual treatments and prevention and intervention programs. The assessment of an individual's attachment organization, can play a crucial role in explaining and previewing the unfolding treatment, the relational adjustments or concerns, and the psychological well-being. We hope to receive empirical papers that give evidence for the usefulness of attachment assessment in both clinical (e.g., patients with Eating Disorder; or Axis-II; psychotherapy patients…) or not clinical population (e.g. Adoptive and/or foster families or couples, Mother-infant assessment in prevention field…). These papers should include methodological issues and information about the participants, the methods used to assess attachment, the process of scorer training and the availability of the manual used to obtain inter-scorer reliability. Case studies may be of interest to the extent that they demonstrate the value of a systematic approach to attachment material. A range of theoretical perspectives is welcome as well presentation of new emergent tools on attachment. Because Frontiers in Psychology is an international journal, each empirical paper should comment on the international implications of the findings and discuss its cross-cultural use. Such comments may include, for example, its linguistic specificity, its robustness in translation, and the cross-cultural generalizability of the constructs and behaviors of the measure and its usual correlates. Cross-cultural generalizability is not, however, a requirement.
    Keywords: BF1-990 ; Q1-390 ; Parenting ; Obesity ; Anorexia ; Treatment ; Addiction ; Attachment ; Trauma ; autism ; Adoption ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 168
    Publication Date: 2024-03-31
    Description: Swimming is an integral part of the life history of many fish species as is intimately linked with their ability to express feeding and predator avoidance behaviors, habitat selection and environmental preferences, social and reproductive behaviors as well as migratory behaviors. Therefore, swimming is an important determinant factor of fitness in a true Darwinian sense and, not surprisingly, swimming performance has been often used as a measure of physiological fitness in fish. The main aim of this Research Topic is to showcase some of the current studies designed to improve our understanding of the physiological energetic and metabolic requirements of swimming and of the adaptive responses to swimming in fish.
    Keywords: QP1-981 ; GC1-1581 ; Q1-390 ; swimming economy ; performance ; fish ; swimming exercise ; growth ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 169
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    Éditions de la Maison des sciences de l’homme
    Publication Date: 2023-12-20
    Description: Le traitement cognitif de l'espace par un être vivant se décompose en différentes phases : il perçoit l'espace – ce qui implique certains mécanismes de catégorisation et d'abstraction –, se le représente, conserve en mémoire cette représentation qu'il peut rappeler et utiliser pour conduire des actions adaptées et interagir de façon optimale avec l'environnement. Ce traitement ainsi défini a déjà fait l'objet d'un grand nombre de travaux dans le domaine des sciences de la vie et de la psychologie expérimentale, de l'intelligence artificielle ou encore de la robotique. Pourtant les réalisations des sciences dites « dures » ne laissent pas de poser des questions sur lesquelles les sciences humaines et sociales sont susceptibles d'apporter un éclairage pertinent. D'une part, leur apport est de nature à renouveler la problématique cognitive de l'espace, notamment en mettant en lumière l'incidence des facteurs culturels et sociétaux sur les représentations spatiales ainsi que la complexité des interactions entre la nature de ces représentations et l'utilisation effective de l'espace depuis la conception et la gestion des cartes géographiques, jusqu'à celle de l'habitat urbain. D'autre part, ces mêmes sciences s'avèrent incontournables si l'on veut tenter de répondre aux multiples questions soulevées par la notion d'action en vue de l'étude de ses différents déterminants : le mécanisme et les représentations mis en œuvre dans la prise de décision, la programmation motrice et sa régulation dans la conscience d'agir et l'interprétation de l'action, dans son caractère multidimensionnel et évolutif, dans la dynamique des interactions et de l'action collective, etc. Les contributions ici rassemblées illustrent toutes ces perspectives, démontrant que seule une interdisciplinarité bien conduite peut permettre de répondre aux défis posés par la problématique cognitive de l'agir dans l'espace.
    Keywords: Q1-390 ; perception spatiale ; son ; langage ; travail ; mouvement ; jeux ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: French
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  • 170
    Publication Date: 2024-04-05
    Description: Genetically encoded indicators emerged as promising tools for cell type-specific and chronic recording of neuronal population activity. Since publication of the first prototypical genetically encoded Ca2+ indicators (Cameleons) in 1997, we have witnessed remarkable evolution of the field, with rapid improvement of indicator performance as well as expanded application to many model organisms in the neuroscience community. Challenges still remain, however, concerning the mammalian central nervous system: limited sensitivity of indicators to subtle changes in activity, slow signal kinetics, cytotoxicity after a long-term and high-level expression of indicators, and variable performance across cell types. In addition to improvement of the indicators per se, development of strategies that allow combined use of the indicators and optogenetic tools is also desired. In this Research Topic, we recruited top researchers in the field and their young colleagues to present their cutting-edge research as well as insightful opinions on the following subtopics: 1) Latest breakthroughs on development of genetically encoded indicators 2) Novel scientific findings obtained with genetically encoded indicators 3) Wishlist for the next-generation genetically encoded indicators 4) Guideline for selecting an appropriate indicator 5) Optimal methodology for indicator delivery to mammalian CNS
    Keywords: RC321-571 ; Q1-390 ; in vivo imaging ; Genetically encoded calcium indicators (GECIs) ; genetically encoded voltage sensor ; Fluorescent protein sensors ; genetically encoded sensors ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 171
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: In 2011, carbohydrates provided 63% of the dietary energy intake to the world’s population. Historically, carbohydrate-rich diets have been associated with good health and longevity but there has been a move away from traditional carbohydrate-rich diets, with refined carbohydrate taking much criticism for contributing to non-communicable disease. The aim of this Special Issue is to discuss the appropriate use of environmentally sustainable carbohydrate-rich foods in the modern diet in developing and developed countries in the context of prevention and treatment of non-communicable disease.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; satiety ; preload ; carbohydrate ; observational study ; body weight ; chronic disease risk ; postprandial ; isomaltulose ; qualitative ; glycaemic glucose equivalents ; mixed meal ; glycaemia ; obesity ; kiwifruit ; knowledge ; carbohydrates ; sugars ; timing ; sucrose ; CVD ; nutrition ; glycemia ; prebiotics ; intestinal biota ; glycemic response ; fibre ; T2DM ; low-carbohydrate diet ; ethnicity ; rice consumption ; activity ; fruit ; exercise ; discussion groups ; potato ; resistant starch ; pasta ; type 2 diabetes mellitus ; glycemic index ; vitamin C ; carbohydrate exchanges ; fructose ; glycemic load ; Japanese diet ; rice ; type 2 diabetes ; glycaemic response ; dietary pattern ; insulinaemia ; diabetes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 172
    Publication Date: 2023-12-20
    Description: Intracellular pathogens, such as bacteria and parasites, have evolved specialized mechanisms to survive and replicate in their host, leading to disorders and diseases. The principle of these mechanisms is to reprogram the microbicidal cell function in order to disable the host cells defence that aims to control and eliminate foreign invaders. Devoid of their defence, cells become permissive to pathogens invasion. The aim of this Research Topic is to highlight and cover recent understanding of mechanisms and molecules used by pathogens to interfere with the microbicidal function of cells. This Research Topic will focus on the reprogramming of the cellular dynamics, the immune response, the phagolysosome biogenesis and the signal transduction pathways bypathogens. Special attention will be made on non-proteic virulence factors, however this Research Topic is not restricted to non-proteic virulence factors.
    Keywords: Q1-390 ; RC109-216 ; rab ; RNAi ; Ubiquitination ; host-pathogens interaction ; Coxiella ; Brucella ; Planarians ; Body Lices ; mycobacteria ; granulomas ; Leshmania ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 173
    Publication Date: 2024-03-29
    Description: Music impinges upon the body and the brain. As such, it has significant inductive power which relies both on innate dispositions and acquired mechanisms and competencies. The processes are partly autonomous and partly deliberate, and interrelations between several levels of processing are becoming clearer with accumulating new evidence. For instance, recent developments in neuroimaging techniques, have broadened the field by encompassing the study of cortical and subcortical processing of the music. The domain of musical emotions is a typical example with a major focus on the pleasure that can be derived from listening to music. Pleasure, however, is not the only emotion to be induced and the mechanisms behind its elicitation are far from understood. There are also mechanisms related to arousal and activation that are both less differentiated and at the same time more complex than the assumed mechanisms that trigger basic emotions. It is imperative, therefore, to investigate what pleasurable and mood-modifying effects music can have on human beings in real-time listening situations. This e-book is an attempt to answer these questions. Revolving around the specificity of music experience in terms of perception, emotional reactions, and aesthetic assessment, it presents new hypotheses, theoretical claims as well as new empirical data which contribute to a better understanding of the functions of the brain as related to musical experience.
    Keywords: BF1-990 ; Q1-390 ; Functions of the brain ; Pleasure-Pain Principle ; Music ; Arousal ; Emotions ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 174
    Publication Date: 2024-03-29
    Description: Mathematical anxiety is a feeling of tension, apprehension or fear which arises when a person is faced with mathematical content. The negative consequences of mathematical anxiety are well-documented. Students with high levels of mathematical anxiety might underperform in important test situations, they tend to hold negative attitudes towards mathematics, and they are likely to opt out of elective mathematics courses, which also affects their career opportunities. Although at the university level many students do not continue to study mathematics, social science students are confronted with the fact that their disciplines involve learning about statistics - another potential source of anxiety for students who are uncomfortable with dealing with numerical content. Research on mathematical anxiety is a truly interdisciplinary field with contributions from educational, developmental, cognitive, social and neuroscience researchers. The current collection of papers demonstrates the diversity of the field, offering both new empirical contributions and reviews of existing studies. The contributors also outline future directions for this line of research.
    Keywords: BF1-990 ; Q1-390 ; Measurement ; Statistics anxiety ; Anxiety specificity ; developmental change ; emotional factors ; Mathematical anxiety ; mathematics performance ; gender differences ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 175
    Publication Date: 2024-04-05
    Description: Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of “selfishness”, based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these “silent” chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems.
    Keywords: QH301-705.5 ; Q1-390 ; parent-of-origin effects ; fluorescent in situ hybridization ; coverage ratio analysis ; n/a ; ribosomal DNA ; reactivation ; cytogenetics ; epigenetics ; heterochromatin ; interphase nucleus ; whole genome resequencing ; transmission ; grasshoppers ; genome instability ; dot-like (micro) Bs ; ?s ; B chromosome ; supernumerary elements ; transcription of heterochromatin ; maternal X chromosome ; supernumerary chromosome ; population analysis ; supernumerary ; repeat clusters ; extra chromosomes ; genes ; tandem repeats ; B morphotypes ; repetitive DNA ; repetitive elements ; DNA copy number variation ; chromosome polymorphism ; satellite DNA ; mammals ; maize B chromosome ; additional chromosomes ; inactivation ; drive ; B chromosomes ; FISH (fluorescence in situ hybridisation) ; organelle DNA ; Orthoptera ; origin ; supernumerary chromosomes ; karyotype evolution ; GISH (genomic in situ hybridisation) ; DNA composition ; de novo centromere formation ; genomics ; paternal X chromosome ; euchromatin degradation ; supernumerary chromosomal segments (SCS) evolution ; centromere ; sSMC ; Prospero autumnale complex ; next-generation sequencing ; Drosophila ; host/parasite interaction ; Apodemus peninsulae ; genome evolution ; evolution ; teleost ; chromosome evolution ; microdissected DNA probes ; controlling element ; mobile element ; RNA-Seq ; karyotypes ; karyotypic characteristics ; RepeatExplorer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 176
    Publication Date: 2024-03-29
    Description: Multitasking refers to performance of multiple tasks. The most prominent types of multitasking are situations including either temporal overlap of the execution of multiple tasks (i.e., dual tasking) or executing multiple tasks in varying sequences (i.e., task switching). In the literature, numerous attempts have aimed at theorizing about the specific characteristics of executive functions that control interference between simultaneously and/or sequentially active component of task-sets in these situations. However, these approaches have been rather vague regarding explanatory concepts (e.g., task-set inhibition, preparation, shielding, capacity limitation), widely lacking theories on detailed mechanisms and/ or empirical evidence for specific subcomponents. The present research topic aims at providing a selection of contributions on the details of executive functioning in dual-task and task switching situations. The contributions specify these executive functions by focusing on (1) fractionating assumed mechanisms into constituent subcomponents, (2) their variations by age or in clinical subpopulations, and/ or (3) their plasticity as a response to practice and training.
    Keywords: BF1-990 ; Q1-390 ; cognitive plasticity ; multitasking ; task switching ; dual tasking ; cognitive flexibility ; PRP ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 177
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    Frontiers Media SA
    Publication Date: 2022-01-31
    Description: Type I chaperonins are key players in maintaining the proteome of bacteria and organelles of bacterial origin. They are well known for their crucial role in mediating protein folding. For almost three decades, the molecular mechanism of chaperonin function has been the subject of intensive research. Still, surprising new mechanistic discoveries are constantly reported. It seems that we are far from having a full understanding of the chaperonin mode of action. Chaperonins are not simply protein folding machines. They also perform diverse extramitochondrial tasks, mainly related to inflammatory and signal transduction processes. This eBook constitutes ten articles highlighting the latest developments related to the divers functions of Type I chaperonins. As its title, mechanism and beyond, the collection starts with mechanistic view, continues with extracellular functions and ends with biotechnological applications of Type I chaperonins.
    Keywords: Q1-390 ; Hsp60 ; GroEL ; chaperonin ; Hsp10 ; GroES
    Language: English
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  • 178
    Publication Date: 2024-03-31
    Description: Current regulatory guidelines for cardiac safety utilize hERG block and QT interval prolongation as risk markers. This strategy has been successful at preventing harmful drugs from being marketed, but criticized for leading to early withdrawal of potentially safe drugs. Here we collected a series of articles presenting new technological and conceptual advances, including refinement of ex vivo and in vitro assays, screens and models, and in silico approaches reflecting the increasing effort that has been put forward by regulatory agencies, industry, and academia to try and address the need of a more accurate, mechanistically-based paradigm of proarrhythmic potential of drugs. This Research Topic is dedicated to the memory of Dr. J. Jeremy Rice, our wonderful friend and colleague.
    Keywords: QP1-981 ; Q1-390 ; cardiotoxicity ; cardiac electrophysiology. ; drug-induced arrhythmia ; QT interval prolongation ; multi-scale modeling ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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  • 179
    Publication Date: 2024-04-05
    Description: The nature is a generous source of a number of compounds with potential application for the treatment of several diseases including the infectious diseases, which is of utmost concern for the modern medicine due to the observed striding antimicrobial resistance. A number of sources of natural compounds with valuable and clinical antimicrobial activity can be listed, comprising medicinal plants, marine and terrestrial organisms, which includes fungi and bacteria. Nevertheless, there is still a vast fauna and flora that, once systematically explored, could provide additional antimicrobial leads and drugs. Investigators were invited to contribute with original research and/or review articles on this area, specifically with studies exploiting the mechanism of action and the structure-activity aspects of natural compounds with antimicrobial activity that provides insights on potential ways to overcome the antimicrobial resistance. Therefore, thanks to the contribution of active researchers in the field, several scientific studies mainly focused on natural products with antimicrobial activity are presented in this Research Topic Ebook.
    Keywords: QR1-502 ; Q1-390 ; antimicrobial ; natural compounds ; antiseptic ; preservation ; Peptides ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 180
    Publication Date: 2022-01-31
    Description: Noise and vibrations generated by ships affect a wide range of receivers: crew and passengers inside the vessel, inhabitants of the coastal areas and marine fauna outside it. Recent studies suggest that a large percentage of people living in urban areas close to harbors and a number of marine species, at different evolutionary levels (in particular mammals and cephalopods), suffer from ship N&V emissions in air and in water. The present degree of knowledge of the phenomena involved in the noise emissions inside and outside ships is quite different, as a result also of the time elapsed since the negative effects were realized and therefore studied. The development of the normative framework in the various areas reflects these differences, but there are expectations for improvements on all fronts that need to be supported by the scientific community presenting the latest research results in this particular field of acoustics.
    Keywords: GC1-1581 ; Q1-390 ; Animal Bioacoustics ; harbour noise ; maritime acoustics ; Underwater soundscape ; ship noise ; sonar ; underwater radiated noise ; Propagation loss ; anthropogenic noise ; sound propagation
    Language: English
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  • 181
    Publication Date: 2024-04-05
    Description: Everyday we vicariously experience a range of states that we observe in other people: we may "feel" embarrassed when witnessing another making a social faux pas, or we may feel sadness when we see a loved one upset. In some cases this process appears to be implicit. For instance, observing pain in others may activate pain-related neural processes but without generating an overt feeling of pain. In other cases, people report a more literal, conscious sharing of affective or somatic states and this has sometimes been described as representing an extreme form of empathy. By contrast, there appear to be some people who are limited in their ability to vicariously experience the states of others. This may be the case in several psychiatric, neurodevelopmental, and personality disorders where deficits in interpersonal understanding are observed, such as schizophrenia, autism, and psychopathy. In recent decades, neuroscientists have paid significant attention to the understanding of the “social brain,” and the way in which neural processes govern our understanding of other people. In this Research Topic, we wish to contribute towards this understanding and ask for the submission of manuscripts focusing broadly on the neural underpinnings of vicarious experience. This may include theoretical discussion, case studies, and empirical investigation using behavioural techniques, electrophysiology, brain stimulation, and neuroimaging in both healthy and clinical populations. Of specific interest will be the neural correlates of individual differences in traits such as empathy, how we distinguish between ourselves and other people, and the sensorimotor resonant mechanisms that may allow us to put ourselves in another's shoes.
    Keywords: RC321-571 ; Q1-390 ; synaesthesia ; Pain ; social cognition ; social neuroscience ; vicarious experience ; Empathy ; Personality ; Mirror Neurons ; Touch ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 182
    Publication Date: 2023-12-20
    Description: Un concept-valise ? Une auberge espagnole ? Un lieu commun médiatique ? Un sujet de société ? Un nouvel objet scientifique ? Une figure de l’angoisse sociale ? Quelle est la part de la réalité et quelle est celle de nos représentations collectives ? Faut-il en attendre des bénéfices ou faudra-t-il en supporter les inconvénients ? À quels coûts et pour qui ? Qu’est-ce donc que le changement ? Qu’est-ce que le changement environnemental en particulier ? Anticiper, agir, réagir, pour ne pas subir...
    Keywords: Q1-390 ; climat ; climatologie ; environnement ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: French
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  • 183
    Publication Date: 2024-03-29
    Description: A recent wave of brain research has advanced our understanding of the neural mechanisms of conscious states, contents and functions. A host of questions remain to be explored, as shown by lively debates between models of higher vs. lower-order aspects of consciousness, as well as global vs. local models. (Baars 2007; Block, 2009; Dennett and Cohen, 2011; Lau and Rosenthal, 2011). Over some twenty-five centuries the contemplative traditions have also developed explicit descriptions and taxonomies of the mind, to interpret experiences that are often reported in contemplative practices (Radhakrishnan & Moore, 1967; Rinbochay & Naper, 1981). These traditional descriptions sometimes converge on current scientific debates, such as the question of conceptual vs. non-conceptual consciousness; reflexivity or “self-knowing” associated with consciousness; the sense of self and consciousness; and aspects of consciousness that are said to continue during sleep. These real or claimed aspects of consciousness have not been fully integrated into scientific models so far. This Research Topic in Consciousness Research aims to provide a forum for theoretical proposals, new empirical findings, integrative literature reviews, and methodological improvements inspired by meditation-based models. We include a broad array of topics, including but not limited to: replicable findings from a variety of systematic mental practices; changes in brain functioning and organization that can be attributed to such practices; their effects on adaptation and neural plasticity; measurable effects on perception, cognition, affect and self-referential processes. We include contributions that address the question of causal attribution. Many published studies are correlational in nature, because of the inherent difficulty of conducting longitudinal experiments based on a major lifestyle decision, such as the decision to commit to a mental practice over a period of years. We also feature clinical and case studies, integrative syntheses and significant opinion articles.
    Keywords: BF1-990 ; Q1-390 ; contemplative practice ; structural plasticity ; functional plasticity ; Meditation ; mindfulness ; neural correlates of consciousness ; Cultural issues ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 184
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    KIT Scientific Publishing
    Publication Date: 2023-07-05
    Description: This book describes the development of a new method for personalisation of efficiency factors in partial body counting. Its achieved goal is the quantification of uncertainties in those factors due to variation in anatomy of the measured persons, and their reduction by correlation with anthropometric parameters. The method was applied to a detector system at the In Vivo Measurement Laboratory at Karlsruhe Institute of Technology using Monte Carlo simulation and computational phantoms.
    Keywords: Q1-390 ; Computational phantom ; Maschinelles Lernen ; Anthropometry ; Partial body counter ; Efficiency calibration ; Machine learning ; Teilkörperzähler ; Computerphantom ; Effizienzkalibrierung ; Anthropometrie
    Language: English
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  • 185
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: This book is a printed edition of the Special Issue Recent Advances in Water Management: Saving, Treatment and Reuse that was published in Water
    Keywords: GE1-350 ; Q1-390 ; anaerobic processes ; risk assessment ; B. adusta ; environmental education ; foreign countries ; ornamental plants ; filter media ; Pb(II) ; passive treatment systems ; lignin ; oxygen injection ; water treatment ; guidelines ; microbiological quality ; membrane technology ; contaminated sites ; pulp-and-paper-mill c ; milk production ; wastewater ; efficiency ; forest waste ; vertical flow ; emerging contaminant ; decomposition analysis ; active sites ; water ; sustainability ; water treatment technology ; adsorption thermodynamic ; surface water ; agricultural occupations ; zeolite ; conservation ; trickling filter ; hydrogen sulfide ; nitrification ; organic matter ; constructed wetlands ; sewerage ; water recycling ; treated wastewater reuse ; advanced oxidation processes (AOPs) ; odor control ; anammox bacteria ; wastewater treatment ; ferrous iron ; combined sewer ; surveys ; occurrence ; denitrification ; research and development strategy ; carbamazepine toxicity ; global patent data ; activated carbon adsorption ; China ; food industry ; COD ; palm mulch ; ferrous sulfide ; nano illite/smectite clay ; pharmaceuticals ; footprint ; conventional treatment processes ; anticorrosive agent ; pumping mains ; adsorption kinetics ; swine wastewater ; P. crysosporium ; micropollutant removal ; tezontle ; delignification ; partitioning ; white rot fungi ; river ; anaerobic digester ; benzotriazole ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics
    Language: English
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  • 186
    Publication Date: 2024-03-29
    Description: Nowadays, not only psychologists are interested in the study of Emotional Intelligence (EI). Teachers, educator, managers, employers, and people, in general, pay attention to EI. For example, teachers would like to know how EI could affect student’s academic results, and managers are concerned about how EI influences their employees’ performance. The concept of EI has been widely used in recent years to the extent that people start to applying it in daily life. EI is broadly defined as the capacity to process and use emotional information. More specifically, according to Mayer and Salovey, EI is the ability to: “1) accurate perception, appraise, and expression of emotion; 2) access and/or generation of feelings when they facilitate thought; 3) understand emotions and emotional knowledge; and 4) regulate emotions to promote emotional and intellectual growth” (Mayer and Salovey 1997, p. 10). When new information arises into one specific area of knowledge, the work of the scientists is to investigate the relation between this new information and other established concepts. In this sense, EI could be considered as a new framework to explain human behaviour. As a young concept in Psychology, EI could be used to elucidate the performance in the activities of everyday life. Over the past two decades, studies of EI have tried to delimitate how EI is linked to other competences. A vast number of studies have reported a relation between EI and a large list of competences such as academic and work success, life satisfaction, attendee to emotions, assertiveness, emotional expression, emotional-based decision making, impulsive control, stress management, among others. Moreover, recent researches have shown that EI plays an important role in the prediction of behaviour besides personality and cognitive factors. However, it is not until quite recently, that studies on EI have considered the importance of individual differences in EI and their interaction with cognitive abilities. The general issue of this Research Topic was to expose the role of individual differences on EI in the development of a large number of competencies that support a more efficient performance in people’s everyday life. The present Research Topic provide an extensive review that may give light to the better understanding of how individual differences in EI affect human behaviour. We have considered studies that analyse: 1) how EI contributes to emotional, cognitive and social process beyond the well-known contribution of IQ and personality traits, as well as the brain system that supports the EI; 2) how EI contributes to relationships among emotions and health and well-being, 3) the roles of EI during early development and the evaluation in different populations, 4) how implicit beliefs about emotions and EI influence emotional abilities.
    Keywords: BF1-990 ; Q1-390 ; emotion ; Well-being ; Intelligence ; Health ; Personality ; cognitive abilities ; creativity ; Emotional Intelligence ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 187
    Publication Date: 2022-01-31
    Description: Deforestation and land use change have led to a strong reduction of tropical forest cover during the last decades. Climate change will amplify the pressure to the remaining refuges in the next years. In addition, tropical regions are facing increasing atmospheric inputs of nutrients, which will have unknown consequences for the structure and functioning of these systems, no matter if they are within protected areas or not. Even remote areas are expected to receive rising amounts of nutrients. The effects of higher rates of atmospheric nutrient deposition on the biological diversity and ecosystem functioning of tropical ecosystems are poorly understood and our knowledge of nutrient fluxes and nutrient limitation in tropical forest ecosystems is still limited. Yet, it will be of paramount importance to know the effects of increased nutrient availability to conserve these ecosystems with their biological and functional diversity. During the last years, research efforts have more and more focused on the understanding of the role of nutrients in tropical ecosystems and several coordinated projects have been established that study the effects of experimental nutrient addition. This Research Topic combines results from experiments and from observational studies with the aim to review and conclude on our current knowledge on the role of additional nutrients in ecosystems.
    Keywords: GB3-5030 ; Q1-390 ; experimental nutrient manipulation ; global change ; nitrogen ; CO2 ; nutrient limitation ; foliar nutrients ; biogeochemical cycles ; wood anatomy ; phosphorus
    Language: English
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  • 188
    Publication Date: 2024-04-05
    Description: From the propagation of neural activity through synapses, to the integration of signals in the dendritic arbor, and the processes determining action potential generation, virtually all aspects of neural processing are plastic. This plasticity underlies the remarkable versatility and robustness of cortical circuits: it enables the brain to learn regularities in its sensory inputs, to remember the past, and to recover function after injury. While much of the research into learning and memory has focused on forms of Hebbian plasticity at excitatory synapses (LTD/LTP, STDP), several other plasticity mechanisms have been characterized experimentally, including the plasticity of inhibitory circuits (Kullmann, 2012), synaptic scaling (Turrigiano, 2011) and intrinsic plasticity (Zhang and Linden, 2003). However, our current understanding of the computational roles of these plasticity mechanisms remains rudimentary at best. While traditionally they are assumed to serve a homeostatic purpose, counterbalancing the destabilizing effects of Hebbian learning, recent work suggests that they can have a profound impact on circuit function (Savin 2010, Vogels 2011, Keck 2012). Hence, theoretical investigation into the functional implications of these mechanisms may shed new light on the computational principles at work in neural circuits. This Research Topic of Frontiers in Computational Neuroscience aims to bring together recent advances in theoretical modeling of different plasticity mechanisms and of their contributions to circuit function. Topics of interest include the computational roles of plasticity of inhibitory circuitry, metaplasticity, synaptic scaling, intrinsic plasticity, plasticity within the dendritic arbor and in particular studies on the interplay between homeostatic and Hebbian plasticity, and their joint contribution to network function.
    Keywords: RC321-571 ; Q1-390 ; Intrinsic Plasticity ; structural plasticity ; heterosynaptic plasticity ; Homeostasis ; reward-modulated learning ; synaptic plasticity ; STDP ; inhibitory plasticity ; metaplasticity ; short-term plasticity ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 189
    Publication Date: 2023-12-20
    Description: A aplicação da química teórica no estudo de materiais é apresentada neste livro na forma de capítulos que dispõem o conteúdo embasado nas pesquisas científicas realizadas por renomados pesquisadores brasileiros. O intuito desta obra é divulgar a aplicabilidade de metodologias computacionais na interpretação e ou previsão de processos físico-químicos relevantes no estudo de materiais. Desta forma, pesquisadores poderão se inteirar das potencialidades oferecidas pelas metodologias computacionais e como estes métodos podem agregar valor as suas respectivas linhas de atuação. Ademais, esta divulgação poderá impactar de forma positiva nas relações entre pesquisadores teóricos e experimentais para o estabelecimento de pesquisas mais colaborativas e de ponta.
    Keywords: Q1-390 ; SCIENCE ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: Portuguese
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  • 190
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    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: This Special Issue focuses mainly on techniques and the relative formalism typical of numerical methods and therefore of numerical analysis, more generally. These fields of study of mathematics represent an important field of investigation both in the field of applied mathematics and even more exquisitely in the pure research of the theory of approximation and the study of polynomial relations as well as in the analysis of the solutions of the differential equations both ordinary and partial derivatives. Therefore, a substantial part of research on the topic of numerical analysis cannot exclude the fundamental role played by approximation theory and some of the tools used to develop this research. In this Special Issue, we want to draw attention to the mathematical methods used in numerical analysis, such as special functions, orthogonal polynomials, and their theoretical tools, such as Lie algebra, to study the concepts and properties of some special and advanced methods, which are useful in the description of solutions of linear and nonlinear differential equations. A further field of investigation is dedicated to the theory and related properties of fractional calculus with its adequate application to numerical methods.
    Keywords: QA1-939 ; Q1-390 ; risk assessment ; complex Lagrangian ; effective order ; logarithmic singularities ; Swift–Hohenberg type of equation ; Cauchy singularity ; differential equations ; unitary extension principle ; oscillatory solutions ; coupling impedance ; Fredholm integral equations ; dual integral equations ; composition properties ; delay differential equations ; chemical reaction ; Noether symmetries ; symplectic Runge–Kutta methods ; order conditions ; non-homogeneous ; wavelets ; multiresolution analysis ; narrow band domain ; pseudo-Chebyshev polynomials ; highly oscillatory integrals ; tight framelets ; Chebyshev polynomials ; nonoscillatory solutions ; ignition hazard ; quad-colored trees ; general solution ; operator splitting method ; fourth-order ODEs ; offshore plant ; special function ; second-order ; surfaces ; numerical analysis ; effective field strength ; closest point method ; oblique extension principle ; heat generation ; B-splines ; Runge-Kutta type methods ; orthogonality properties ; Frobenius method ; hamiltonian systems ; B-series ; k-hypergeometric series ; particle accelerator ; first integrals ; partitioned runge-kutta methods ; Clenshaw-Curtis quadrature ; recurrence relations ; thin needle ; nanofluid ; Hamiltonian system ; k-hypergeometric differential equations ; steepest descent method ; symplecticity ; fourth-order ; bic Book Industry Communication::P Mathematics & science
    Language: English
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  • 191
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    Unknown
    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: In this century the human being must face the challenges of producing enough to feed a growing population in a sustainable and environmentally friendly way. The yields are with increasing frequency affected by abiotic stresses such as salinity, drought, and high temperature or by new diseases and plagues. The Research Topic on Induced Resistance for Plant Defense focuses on the understanding the mechanisms underlying plant resistance or tolerance since these will help us to develop fruitful new agricultural strategies for a sustainable crop protection. This topic and its potential applications provide a new sustainable approach to crop protection. This technology currently can offer promising molecules capable to provide new long lasting treatments for crop protection against biotic or abiotic stresses. The aim of this Research Topic is to review and discuss current knowledge of the mechanisms regulating plant induced resistance and how from our better understanding of these mechanisms we can find molecules capable of inducing this defence response in the plant, thereby contributing to sustainable agriculture we need for the next challenges of the XXI century.
    Keywords: QK1-989 ; Q1-390 ; priming ; plant defence activators ; induced resistance ; elicitors ; abiotic stress ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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  • 192
    Publication Date: 2024-03-31
    Description: The current eBook collection includes substantial scientific work in describing how insect species are responding to abiotic factors and recent climatic trends on the basis of insect physiology and population dynamics. The contributions can be broadly split into four chapters: the first chapter focuses on the function of environmental and mostly temperature driven models, to identify the seasonal emergence and population dynamics of insects, including some important pests. The second chapter provides additional examples on how such models can be used to simulate the effect of climate change on insect phenology and population dynamics. The third chapter focuses on describing the effects of nutrition, gene expression and phototaxis in relation to insect demography, growth and development, whilst the fourth chapter provides a short description on the functioning of circadian systems as well as on the evolutionary dynamics of circadian clocks.
    Keywords: QP1-981 ; Q1-390 ; environment ; modeling insect phenology ; ectotherms ; temperature ; diapause ; insects ; circadian rithms ; climate change ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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  • 193
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    Unknown
    Frontiers Media SA
    Publication Date: 2024-03-31
    Description: Echolocation has evolved in different groups of animals, from bats and cetaceans to birds and humans, and enables localization and tracking of objects in a dynamic environment, where light levels may be very low or absent. Nature has shaped echolocation, an active sense that engages audiomotor feedback systems, which operates in diverse environments and situations. Echolocation production and perception vary across species, and signals are often adapted to the environment and task. In the last several decades, researchers have been studying the echolocation behavior of animals, both in the air and underwater, using different methodologies and perspectives. The result of these studies has led to rich knowledge on sound production mechanisms, directionality of the sound beam, signal design, echo reception and perception. Active control over echolocation signal production and the mechanisms for echo processing ultimately provide animals with an echoic scene or image of their surroundings. Sonar signal features directly influence the information available for the echolocating animal to perceive images of its environment. In many echolocating animals, the information processed through echoes elicits a reaction in motor systems, including adjustments in subsequent echolocation signals. We are interested in understanding how echolocating animals deal with different environments (e.g. clutter, light levels), tasks, distance to targets or objects, different prey types or other food sources, presence of conspecifics or certain predators, ambient and anthropogenic noise. In recent years, some researchers have presented new data on the origins of echolocation, which can provide a hint of its evolution. Theoreticians have addressed several issues that bear on echolocation systems, such as frequency or time resolution, target localization and beam-forming mechanisms. In this Research Topic we compiled recent work that elucidates how echolocation – from sound production, through echolocation signals to perception- has been shaped by nature functioning in different environments and situations. We strongly encouraged comparative approaches that would deepen our understanding of the processes comprising this active sense.
    Keywords: QP1-981 ; Q1-390 ; bats ; Biosonar ; Humans ; marine mammals ; sensory biology ; Birds ; Behavior ; Communication ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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  • 194
    Publication Date: 2023-12-20
    Description: Global population growth is urban growth and, therefore, most of the water-related challenges and solutions reside in cities. Unless water management and water governance processes are significantly improved within the next decade or so, cities are likely to face serious and prolonged water insecurity, urban floods, and/or heat stress, which may result in social instability and, ultimately, massive migration. Aging water infrastructure, one of the most expensive infrastructures in cities, is a relevant challenge in order to address Sustainable Development Goal (SDG) 6: clean water and sanitation, SDG 11: sustainable cities and communities, and SDG 13: climate action. The choice of good governance arrangements has important consequences for economic performance, for the well-being of citizens, and for the quality of life in urban areas. The better governance arrangements work in coordinating policies across jurisdictions and policy fields, the better the outcomes. Rapidly-changing global conditions will make future water governance more complex than ever before in human history, and expectations are that water governance and water management will change more during the next 20 years compared to the past 100 years. In this Special Issue of Water, the focus will be on practical concepts and tools for water management and water governance, with a focus on cities.
    Keywords: Q1-390 ; flood resilience ; flood risk ; Cape Town ; Sustainable Development Goals (SDGs) ; sustainable development goals ; urban planning ; coordination ; IHP ; storm water management ; stakeholder involvement ; flood risk management ; water management sustainability ; Generalized Likelihood Uncertainty Estimation (GLUE) ; climate change ; urban water cycle ; wastewater management ; water policy ; governance capacity ; greenhouse gas emissions ; intergovernmental ; Urban Water Management Programme ; indicators ; sustainability ; city networks ; water sensitive cities ; water scarcity ; ICLEI ; flood damage assessment ; stakeholder participation ; SuDS ; climate change mitigation ; social network analysis ; water ecology ; SDGs ; urban resilience ; design rainfall event ; cost of inaction ; rainwater harvesting ; co-design ; UNESCO ; rainfall-runoff ; storm water control measure ; decentralized water reclamation with resource recovery ; baseline assessment ; City Blueprint Approach ; urban water management ; urban landscape ; governance strategies ; science and technology ; drinking water ; Integrated Water Resources Management ; resilience ; Sponge City ; stormwater reservoir ; use-attainment ; sustainability assessment ; water security ; Water-Energy-Food Nexus ; water management ; water supply ; Storm Water Management Model (SWMM) ; urban drainage ; lifecycle analysis ; social infrastructure ; urban pluvial flooding ; assessment framework ; footprint ; climate change adaptation ; infrastructure ; total cost of ownership ; water governance ; flood control ; water-reuse ; governance ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 195
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    Unknown
    Frontiers Media SA
    Publication Date: 2022-01-31
    Description: Besides causing direct damage associated with blood feeding and in some cases through the excretion of toxins with their saliva, the main relevance of ticks lies in the wide variety of pathogens that they can transmit, including viruses, bacteria, protozoa and helminths. Owing to socioeconomic and environmental changes, tick distribution is changing with incursions of ticks and tick-borne diseases occurring in different regions of the world when the widespread deployment of chemical acaricides and repellents has led to the selection of resistance in multiple populations of ticks. New approaches that are environmentally sustainable and that provide broad protection against current and future tick-borne pathogen (TBP) are thus urgently needed. Such development, however, requires improved understanding of factors resulting in vector competence and tick-host-pathogen interactions. This Research Topic provides an overview of known molecular tick-host-pathogen interactions for a number of TBPs and highlights how this knowledge can contribute to novel control and prevention strategies for tick-borne diseases.
    Keywords: Q1-390 ; RC109-216 ; transmission ; Ticks ; host ; tick-borne Pathogens ; pathogen ; Vector ; Tick-Borne Diseases
    Language: English
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  • 196
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    Unknown
    Frontiers Media SA
    Publication Date: 2024-03-29
    Description: The Research Topic aims to highlight research on the processing of words, sentences and discourses across languages. Articles representing processing in a wide variety of human languages will be featured. Efforts will be made to have articles, representing as many language families as possible. The methodology used to investigate language processing is open. Manuscripts may report studies involving monolinguals or individuals knowing more than one language. Research addressing the extent to which all human languages are processed similarly are welcomed as are studies investigating the extent to which the different types of linguistic knowledge are stored differently in memory.
    Keywords: BF1-990 ; Q1-390 ; language processing ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 197
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    Unknown
    Éditions de la Maison des sciences de l’homme
    Publication Date: 2023-12-20
    Description: Depuis ses origines, l'économie est définie au sens large comme la discipline qui étudie les processus de coordination entre les actions d'un certain nombre d'acteurs supposés rationnels. Apparue dans la dernière décennie, l'économie cognitive a pour objet plus spécifique d'étudier les croyances et les raisonnements des acteurs placés dans un contexte d'interaction dynamique. Au niveau individuel, elle entre dans la boîte noire du cerveau humain afin d'examiner comment les acteurs s'appuient sur les informations qu'ils reçoivent pour réviser leurs croyances, adapter leurs préférences et délibérer en combinant ces deux éléments. Au niveau collectif, elle précise les raisons et les modalités des processus de diffusion d'information entre les acteurs, lesquels sont susceptibles d'aboutir asymptotiquement à une homogénéisation des croyances et à une compatibilité des actions. L'économie cognitive se développe simultanément aux deux niveaux de spécification habituels considérés par la théorie économique. Dans la théorie des jeux, des acteurs indifférenciés, pourvus de préférences et de croyances génériques, interagissent de façon stratégique à travers des actions quelconques, sans médiation d'institutions extérieures. Dans la théorie des échanges, les acteurs sont des producteurs et des consommateurs de biens, dotés de croyances et de préférences plus spécifiques, et interagissent par l'intermédiaire d'institutions, l'institution centrale étant le marché qui coordonne les agents par des prix. Ce sont les théories de la communication et du raisonnement interactif entre acteurs présents dans ces jeux et échanges que cet ouvrage propose de décrire et d'expliquer.
    Keywords: Q1-390 ; sciences cognitives ; théorie ; représentations ; économie politique ; croyances ; comportement ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: French
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  • 198
    facet.materialart.
    Unknown
    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Could we understand, in biological terms, the unique and fantastic capabilities of the human brain to both create and enjoy art? In the past decade neuroscience has made a huge leap in developing experimental techniques as well as theoretical frameworks for studying emergent properties following the activity of large neuronal networks. These methods, including MEG, fMRI, sophisticated data analysis approaches and behavioral methods, are increasingly being used in many labs worldwide, with the goal to explore brain mechanisms corresponding to the artistic experience. The 37 articles composing this unique Frontiers Research Topic bring together experimental and theoretical research, linking state-of-the-art knowledge about the brain with the phenomena of Art. It covers a broad scope of topics, contributed by world-renowned experts in vision, audition, somato-sensation, movement, and cinema. Importantly, as we felt that a dialog among artists and scientists is essential and fruitful, we invited a few artists to contribute their insights, as well as their art. Joan Miró said that “art is the search for the alphabet of the mind.” This volume reflects the state of the art search to understand neurobiological alphabet of the Arts. We hope that the wide range of articles in this volume will be highly attractive to brain researchers, artists and the community at large.
    Keywords: RC321-571 ; Q1-390 ; emotion ; neuroesthetics ; performing-arts ; creativity ; perception ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 199
    Publication Date: 2024-04-05
    Description: Phytopathogenic bacteria of the Xanthomonas genus cause severe diseases on hundreds of host plants, including economically important crops, such as bean, cabbage, cassava, citrus, hemp, pepper, rice, sugarcane, tomato or wheat. Diseases occurring in nature comprise bacterial blight, canker, necrosis, rot, scald, spot, streak or wilt. Xanthomonas spp. are distributed worldwide and pathogenic and nonpathogenic strains are essentially found in association to plants. Some phytopathogenic strains are emergent or re-emergent and, consequently, dramatically impact agriculture, economy and food safety. During the last decades, massive efforts were undertaken to decipher Xanthomonas biology. So far, more than one hundred complete or draft genomes from diverse Xanthomonas species have been sequenced (http://www.xanthomonas.org), thus providing powerful tools to study genetic determinants triggering pathogenicity and adaptation to plant habitats. Xanthomonas spp. employ an arsenal of virulence factors to invade its host, including extracellular polysaccharides, plant cell wall-degrading enzymes, adhesins and secreted effectors. In most xanthomonads, type III secretion (T3S) system and secreted effectors (T3Es) are essential to bacterial pathogenicity through the inhibition of plant immunity or the induction of plant susceptibility (S) genes, as reported for Transcription Activation-Like (TAL) effectors. Yet, toxins can also be major virulence determinants in some xanthomonads while nonpathogenic Xanthomonas species do live in sympatry with plant without any T3S systems nor T3Es. In a context of ever increasing international commercial exchanges and modifications of the climate, monitoring and regulating pathogens spread is of crucial importance for food security. A deep knowledge of the genomic diversity of Xanthomonas spp. is required for scientists to properly identify strains, to help preventing future disease outbreaks and to achieve knowledge-informed sustainable disease resistance in crops. This Research Topic published in the ‘Plant Biotic Interactions’ section of Frontiers in Plant Science and Frontiers in Microbiology aims at illustrating several of the recent achievements of the Xanthomonas community. We collected twelve manuscripts dealing with comparative genomics or T3E repertoires, including five focusing on TAL effectors which we hope will contribute to advance research on plant pathogenic bacteria.
    Keywords: QK1-989 ; Q1-390 ; Resistance ; susceptibility ; Xop ; Type III effector ; Immunity ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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  • 200
    Publication Date: 2024-03-31
    Description: Human red blood cells are formed mainly in the bone marrow and are believed to have an average life span of approximately 120 days. However, is it true for all red blood cells? What are the changes associated with red cell maturation, adulthood and senescence? What are the determinants of red cell life span and clearance? What are the mechanisms in control of red cell mass in healthy humans and patients with various forms of anemia? What are the markers of circulating red cell senescence and in cells during storage and transfusion? Within the life span may properties of red cells change leading to age-mixed circulating cell populations. Although these cells appear to be genetically terminated by the time they are released into the blood stream, they undergo surprisingly versatile modifications depending on the life-style and health conditions of a “human host”. Numerous disorders are believed to be associated with facilitated ageing of red blood cells. “In vitro ageing” and damage of red blood cells during storage is yet one more important issue related to the risks and efficiency of blood transfusion. Many of the mechanisms behind such effects are far from being fully understood. In this context the Research Topic is set to include articles in the field of biochemical investigations, biophysical approaches, physiological and clinical studies related to red blood cell maturation and aging. This includes Original Research, Methods, Hypothesis and Theory, Reviews and Perspectives.
    Keywords: QP1-981 ; QH301-705.5 ; Q1-390 ; QC1-999 ; Erythropoiesis ; senescence ; neocytolysis ; blood storage ; Clearance ; Vesiculation ; erythrocyte ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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