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  • Articles  (29,566)
  • Wiley-Blackwell  (10,886)
  • Institute of Physics  (10,106)
  • American Physical Society  (8,165)
  • Nature Publishing Company
  • 1985-1989  (29,566)
  • 1988  (29,566)
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  • 1985-1989  (29,566)
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  • 1
    Electronic Resource
    Electronic Resource
    Biotech Investment Catches Congressional Eye (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1001-1002 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—“This report shows how important biotechnology has already become,” declares Senator Lawton Chiles (D—FL), referring to the fourth in a series on biotechnology prepared by the congressional Office of Technology Assessment (OTA). And Senator Tom Harkin ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1001
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  • 2
    Electronic Resource
    Electronic Resource
    Maneuvering to Break (Proposed) EPA Rules (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1002-1002 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Summers in the capital are nasty, brutish, but long. In the withering heat of 1988, a lengthy set of biotechnology rules proposed by the Environmental Protection Agency (EPA) got badly scorched. This instance of classic Washington-style maneuvering has agency officials ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1002
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  • 3
    Electronic Resource
    Electronic Resource
    Moo–ving BST to Market Stalled by Debate (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1008-1009 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—While Europe seems determined to forbid the use of steroid hormones in beef production, it is edging towards accepting the use of the peptide hormone bovine somatotropin (BST) to increase milk production. Debate on the issue is still widespread, however: it has popped up in a recent ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1008
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  • 4
    Electronic Resource
    Electronic Resource
    Biotechnology Products in the Pipeline (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1004-1007 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Product Name Company Indication Development Status APPROVED THERAPEUTIC PRODUCTS/VACCINES Monoclate Factor VllhC Armour (Rorer) hemophilia approved Humulin Human Insulin of Recombinant DNA Origin Eli Lilly diabetes approved Humatrope Somatropin of Recombinant DNA Origin Eli Lilly human growth ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1004
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  • 5
    Electronic Resource
    Electronic Resource
    1988 Compensation Survey Results (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1013-1018 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The “average” biotechnologist is 44 years old, with 15 years experience in the industry (whichever industry that may be) and nine years invested in his company or institution…making a median $50,000–$60,000 a year in salary, consulting fees, bonuses, ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1013
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  • 6
    Electronic Resource
    Electronic Resource
    The Right Skills for the Job (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1029-1032 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In November 1987, the Molecular Biology/Biotechnology Research and Training Program at East Carolina University polled 103 private and 91 public biotechnology companies. We asked them for information on their products, the mix of skills and training they look for in employees, the starting salaries ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1029
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  • 7
    Electronic Resource
    Electronic Resource
    Executive Hiring Trends: Entrepreneurs and Managers (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1023-1026 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] When Lucy Hathway started recruiting for biotechnology companies five years ago, she couldn't make a living at it. Today, she says, “There's so much business I wish there were eight days in the week.” Hathway, a pharmaceutical and medical specialist at International Search Consultants ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1023
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  • 8
    Electronic Resource
    Electronic Resource
    Yes, Virginia, There is Biotechnology in FRG (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1010-1010 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—“Readers of this report will probably not really be interested in the production of sauerkraut…” sagely concludes an otherwise comprehensive new report on biotechnology in West Germany*. While the RauCon report praises F.R.G.'s level of support for biotechnology, ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1010
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  • 9
    Electronic Resource
    Electronic Resource
    Automated Plant Tissue Culture for Mass Propagation (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1035-1040 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The successful expression of foreign genes in model systems such as tobacco and tomato highlights the enormous potential of the marriage of molecular biology and plant cell culture. But biological and technical problems still hamper the application of these technologies to important food crops such ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1035
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  • 10
    Electronic Resource
    Electronic Resource
    Catabolic Control of Mammalian Cell Culture (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1041-1050 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The burgeoning demand for a growing variety of products of animal cell culture carries an implicit challenge to biochemical engineers: to develop strategies for maximizing bioreactor productivity and efficiency. The obstacles are inherent in the system itself: it is complex (see Fig. 1) and its ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1041
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  • 11
    Electronic Resource
    Electronic Resource
    Advances in Filtration (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1053-1058 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Filtration, like fermentation, represents an ancient art that has grown into a precise, powerful technique. Advances in designing and manufacturing filter systems have made their performance more predictable and their lifetimes longer. Although scientists must still perform in-house testing with ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0988-1053
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  • 12
    Electronic Resource
    Electronic Resource
    Erratum: Immunomodulatory Components Present in IMREG-1, an Experimental Immunosupportive Biologic (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1064-1064 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Due to a production error, Figure 3 in this research paper by Sudhir K. Sinha et al., (Bio/Technology 6:810–815, July '88) was incompletely reproduced. The correct figure is shown below. FIGURE 3, Effects of IMREG-1, and leu-enkephalin on antigen induced γ-IFN production by PBMCs ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1064
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  • 13
    Electronic Resource
    Electronic Resource
    Oligonucleotide Polymorphisms: A New Tool for Genomic Genetics (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1061-1064 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The development of molecular genetic markers, detecting variation at the DNA level, has opened new horizons in the genetic analyses of both man and agricultural species. Agricultural applications of “Restriction Fragment Length Polymorphisms” (RFLPs), despite their promise, are limited ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1061
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  • 14
    Electronic Resource
    Electronic Resource
    Transgenic Rice Plants After Direct Gene Transfer into Protoplasts (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1072-1074 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have regenerated whole plants of rice (Oryza sativa L.) derived from protoplasts, which had been electroporated with plasmid DNA possessing a chimeric gene encoding aminoglycoside phosphotransferase II (APH(3′)II). Transformed calli were selected on the basis of tolerance to the ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1072
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  • 15
    Electronic Resource
    Electronic Resource
    Hepatitis B Surface Antigen as Carrier Matrix for the Repetitive Epitope of the Circumsporozoite Protein of Plasmodium Falciparum . (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1065-1070 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The immune dominant repetitive epitope of the circumsporozoite protein of Plasmodium falciparum was fused to the pre-S2 region of the surface antigen of hepatitis B virus within an expression cassette. Yeast cells transformed with vectors carrying the fusions synthesized hybrid proteins that ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1065
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  • 16
    Electronic Resource
    Electronic Resource
    Presentation of an Antigenic Determinant from Hen Egg-White Lysozyme on the Flagellar Filament of Escherichia Coli (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1080-1083 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We attempted to take an antigenic determinant of hen egg-white lysozyme and present it on the Escherichia coli flagellar filament by inserting a lysozyme-derived fragment into the central region of the filament component protein, flagellin. Random digests of the lysozyme gene were inserted into the ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1080
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  • 17
    Electronic Resource
    Electronic Resource
    Gel Microdroplets: Rapid Detection and Enumeration of Individual Microorganisms by their Metabolic Activity (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1084-1089 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We report a new, flexible method for rapid detection and enumeration of individual microorganisms using small (e.g. 10 to 100 micron diameter) gel particles surrounded by a non-aqueous liquid with low dielectric constant. Primary samples without prior cultivation can be used. In the present study, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0988-1084
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  • 18
    Electronic Resource
    Electronic Resource
    Scanning Microfluorimetry of Ca-Alginate Immobilized Zymomonas Mobilis (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1076-1079 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Scanning microfluorimetric techniques offer a means for in situ investigation of spatial heterogeneities in biomass density and cell composition in macroscopic, aggregate-cell systems such as immobilized-cell biocatalysts, biofilms, mold pellets and tumors. Much of the analytical power of flow ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1076
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  • 19
    Electronic Resource
    Electronic Resource
    Electroporation Increases DNA Synthesis in Cultured Plant Protoplasts (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1091-1093 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] DNA synthesis increased significantly in isolated Prunus and Solanumprotoplasts electroporated at 250V cm−1 for 87 μsec and 750V cm−1 for 29 μsec respectively. This increase correlates with an earlier onset of division of protoplast-derived cells in culture. Inhibition of cell ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1091
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  • 20
    Electronic Resource
    Electronic Resource
    Automated DNA Sequencers (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1095-1096 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Manual DNA sequencing is a labor-intensive, technically difficult, and error-prone process—and an ideal candidate for automation. One main reason why microchemical instrumentation experts are intent on improving DNA sequencing equipment is that automation is essential to the progress of the ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1095
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  • 21
    Electronic Resource
    Electronic Resource
    Synthesizer and Sequencer Products (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1099-1099 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Hoefer Scientific (San Francisco, CA) offers the PR-600 24-place slot-blot filtration manifold to facilitate screening of numerous DNA, RNA, or protein samples. The manifold allows the collection of filtrate separately from each position. Each 6 × 0.80 mm slot is designed to test for the ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1099
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  • 22
    Electronic Resource
    Electronic Resource
    Free Literature (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1106-1106 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] 1988 Pierce catalog. Pierce U.K. Ltd., which is now supplying its products through Life Science Laboratories (Luton, U.K.), includes a wealth of technical data in its handbook of products for chromatography, assays, sequencing, synthesis, and iodination. Write in 705 on Reader Service Card Leitz ...
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  • 23
    Electronic Resource
    Electronic Resource
    New Products (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1100-1104 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] TSH, FSH, and LH pituitary hormones from Porton Products (Salisbury, UK) are purified by affinity chromatography using monoclonal antibodies. The hormones can be used as standards and labelled components, in diagnostic kits and research assays. Write in 618 on Reader Service Card The Microtemp ...
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    URL: http://dx.doi.org/10.1038/nbt0988-1100
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  • 24
    Electronic Resource
    Electronic Resource
    Financing Biotechnology in a Risk-Averse Environment (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1120-1120 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Since October 19, virtually all biotechnology companies have been denied access to capital markets. Even companies that had the foresight (and luck) to salt away a hoard of cash pre-crash are altering their spending and burn rates, anticipating that the situation will not change in the forseeable ...
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  • 25
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    Announcements (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 1107-1107 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] OCTOBER MEETINGS Oct. 3–5. Advances in Recombinant DNA Technology: Genetic Engineering and the Immune System. Incline Village, NV. Info: Symposium Coordinator, The Center for Advanced Training in Cell and Molecular Biology, The Catholic University of America, Washington, DC 20064. Oct. ...
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  • 26
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    Electronic Resource
    We Happy Few (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 991-991 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] From this day to the ending of the world, But we in it shall be remembered — We few, we happy few, we band of brothers…. And gentlemen…now abed Shall think themselves accurs'd they were not here. Henry V [IV.iii] St. Crispin's Day—the anniversary of Henry V's ...
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  • 27
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    Electronic Resource
    Epidermal Growth Factor: Anti-Tumoral Too? (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 997-997 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] HAVANA, CUBA—The discovery a few years ago—that the v-erbB oncogene encodes a truncated form of the human epidermal growth factor receptor (EGF-r)—provided a first look at the structural biochemistry underlying malignant cell transformation. And the subsequent findings—that ...
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  • 28
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    Microcomputer Software Compares 2-D Gels (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 999-999 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—High-powered image-processing workstations dedicated to image-analysis are one way of approaching the daunting task of analyzing 2-D electrophoresis gels. But personal-computer-based software can get the job done for less—about $100,000 less, to be exact. Some can ...
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  • 29
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    Is Our Money Where Our Mouth is? (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 855-855 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Another damned, thick, square book! Always scribble, scribble! Eh, Mr. Gibbon? William Henry, Duke of Gloucester upon receiving the second volume of Edward Gibbon's Decline and Fall of the Roman Empire. The U.S. Congress's Office of Technology Assessment published yet another volume of its epic ...
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  • 30
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    Shake-Ups at Smithkline Beckman and Kodak (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 993-994 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Genentech's roller coaster ride. This South San Francisco, CA company has had its share of ups and downs this summer. One day it's good news, one day it's bad… • A 48-patient study published in an early August issue of The Lancet concluded that Activase (Genentech's t-PA) cleared acute ...
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  • 31
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    Patents; Deals; Pull-Outs; New Firms (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 857-858 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] T-PA patent issues. The Belgian technology-patent firm Innovi N.V.—and its exclusive licensee Genentech (South San Francisco, CA)—have been awarded a broad U.S. patent on t-PA. Predictably, the pair immediately sued the Wellcome Foundation (London, U.K.) and its partner Genetics ...
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  • 32
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    In China, the Dragon Searches for the Pearl (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 863-864 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BEIJING—China is still undergoing massive reconstruction in the aftermath of the Cultural Revolution. Changes intended to bring the nation into the high-tech, modern world are evident everywhere—including massive building and rebuilding of factories, offices, and high-rise apartments. ...
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  • 33
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    Plant Biotechnology—Yet More Novelties (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 865-865 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ARLINGTON, Virginia—Specialized plant structures with odd biochemistry may bring long-term payoffs if persevering researchers prove successful. Investigators are finding that structures as diverse as plant roots and microscopic “cones” found on some leaf surfaces can produce ...
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    Engineered Soybean Becomes a Reality: Advances in Science… (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 870-870 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The two papers—from research groups at Monsanto Co. (St. Louis, MO) and Agracetus (Middleton, WI)—appearing in this month's Bio/Technology mark a milestone in the application of plant genetic engineering to crops of major agricultural importance. Because the germplasm of soybean grown ...
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    Field-Test Rules Need Tuning (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 865-867 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Because of “gaps in regulatory coverage,” the U.S. General Accounting Office (GAO) recommends that two federal agencies modify current policies for the field-testing of genetically engineered organisms. Meanwhile, by continuing to follow a “prudent” ...
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    Large-Scale Rules, Transgenic Animals, International Issues (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 872-872 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—During its June meeting, the Recombinant DNA Advisory Committee (NIHRAC) of the National Institutes of Health (NIH) (Bethesda, MD) carefully considered but could not agree on a proposal for extending its jurisdiction to cover experiments that are conducted outside the United ...
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    …Impact on Agribusiness (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 870-870 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] As the Midwestern soybean crop sears in the heat of the drought of '88, many in the seed industry pray for both rain and future crop improvements—especially the sort of seed improvements that have eluded conventional plant breeders since the Cinderella crop of soybeans blossomed in the United ...
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    Product-Preferred Stocks (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 875-875 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Tough times have a way of encouraging creative solutions—as a new financing vehicle geared toward biotech companies proves. This vehicle, product-preferred stock, offers public firms a way to raise capital without issuing more common stock or taking on new business partners. It ...
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    Myxobacteria Attract New Interest (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 878-878 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BUCK HILL FALLS, Penna.—Even simple, single-celled bacteria are capable of advanced social behavior. A single cell will amass with its kin: Together they move in coordinated fashion across a solid surface, accumulate into aggregation centers, and go on to form morphologically complex fruiting ...
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    New European Collaborations in Biotech (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 883-883 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—A clutch of new industrial biotechnology projects has emerged from EUREKA, originally heralded as Europe's response to the U.S. Strategic Defense Initiative. Immunodiagnostics and immunotherapy, automation of molecular biology procedures, and improvement of corn and fruit crops all ...
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    Japan Roundup (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 880-880 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Scientists at Suntory Ltd.'s (Osaka) Institute for Biomedical Research are developing rDNA techniques for producing human heme proteins, such as superoxide dismutase (SOD), in yeast. They have cloned the human cytochrome c cDNA, linked it to a vector containing the promoter for yeast ...
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    U.K. Biotech a Policy Pawn (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 875-876 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—The Biotechnology Directorate of the U.K. Science and Engineering Research Council (SERC), whose future is already under review, now seems to have had the misfortune of becoming a pawn in a much larger game in British science policy. The end result could be the formation of a new ...
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    Process Regulation and Validation: The Importance of Being Earnest (1988)
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    Nature biotechnology 6 (1988), S. 884-885 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SAN FRANCISCO—Controlling the manufacturing process for a biotech product—be it a drug, a biologic, or a diagnostic—is critical to producing a quality, Food and Drug Administration (FDA)-approvable, product. “You cannot design the quality of a final product: you have to do ...
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    Play with Purpose: Modeling Biotech Processes (1988)
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    Nature biotechnology 6 (1988), S. 887-892 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A model, of course, is a simplified reality meant to be manipulated to increase understanding. Basically, there are three reasons to model a biotechnological process: to embody and test a new hypothesis; to anticipate, track, or reduce costs; to control a production process intelligently. This is ...
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    Hybridoma Growth Factors (1988)
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    Nature biotechnology 6 (1988), S. 895-902 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] There seems to be no end to the uses for monoclonal antibodies. Not only are they invaluable for identifying, characterizing, and purifying their eliciting antigens, but monoclonals are also proving useful as therapeutic agents, solely or in combination with other proteins—such as anti-fibrin ...
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    University and Industry in Agreement (1988)
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    Nature biotechnology 6 (1988), S. 906-910 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A decade ago, it was hard to imagine a more unlikely marriage than that between academe and the private biotechnology sector. Even though most of today's biotech companies can trace their technical—and sometimes financial—origins to one or more universities, the two camps have usually ...
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    Biotechnology Patents in Europe (1988)
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    Nature biotechnology 6 (1988), S. 911-913 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In patent appeals courts on both sides of the Atlantic, biotech companies skirmish for control over markets for their unique products. Yet when the Arthur Young High Technology Group1 (San Francisco, CA) recently asked firms in the U.K. and U.S., “How important are patents and ...
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    Production of Transgenic Soybean Plants Using Agrobacterium -Mediated DNA Transfer (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 915-922 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Transgenic soybean plants have been produced using an Agrobacterium-mediated gene transfer system. This procedure relied on a regeneration protocol in which shoot organogenesis was induced on cotyledons of soybean genotypes selected for susceptibility to Agrobacterium. Cotyledon explants were ...
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    Stable Transformation of Soybean (Glycine Max) by Particle Acceleration (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 923-926 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have used particle acceleration by electric discharge to introduce DNA-coated gold particles into meristems of immature soybean seeds. Approximately 2 percent of shoots derived from these meristems via organogenesis were chimeric for expression of the introduced gene. Experiments using this ...
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    Efficient Production of Active Human Manganese Superoxide Dismutase in Escherichia Coli (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 930-935 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Human manganese superoxide dismutase (hMnSOD) was expressed in Escherichia coli under regulation of the PL promoter and cII ribosomal binding site (rbs), derived from bacteriophage λ. Production of hMnSOD was induced upon temperature shift from 32°C to 42°C. The enzyme accumulated ...
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    Applications of Imaging Spectroscopy in Molecular Biology: I. Screening Photosynthetic Bacteria (1988)
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    Nature biotechnology 6 (1988), S. 939-942 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have developed an imaging spectrophotometer that combines the spatial-resolving properties of a video camera with the wavelength-resolving properties of a spectrophotometer. This instrument is especially useful for screening photosynthetic bacteria, since hundreds of colonies may be analyzed ...
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    Computer Based Visualization for Quantitative and Qualitative Analysis of the Distribution of Matrix-Bound Proteins (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 927-929 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have developed a computer based imaging approach for determining the distribution of immobilized protein within a porous support. The computor-based visualization allows quantitative and qualitative analysis of the protein distribution profile. Microscopic fluorometry of fluorescein ...
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    The Use of Non-Radioactive Oligonucleotide Probes to Analyze Enzymatically Amplified DNA for Prenatal Diagnosis and Forensic HLA Typing (1988)
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    Nature biotechnology 6 (1988), S. 943-947 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Non-radioactive oligonucleotide probes for specific alleles of the HLA-DQα and β-globin loci have been synthesized and applied to forensic analysis and prenatal diagnosis. The results obtained with biotin-labeled, enzyme-labeled, and 32P-labeled probes are compared in the individuality ...
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    Production of Secretable Proteins Using the Passage In Vivo as Tumours of Cells Carrying Heat-Inducible Expression Constructs (1988)
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    Nature biotechnology 6 (1988), S. 953-958 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] We have established cell lines that contain plasmid constructs carrying combinations of genes coding for human growth hormone (hGH) or the human hepatitis B virus surface antigen complex (HBsAg), placed under the expression control of a human heat shock promoter. In addition, neomycin resistance ...
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    Control of Folding of Proteins Secreted by a High Expression Secretion Vector, pIN-III- ompA : 16-Fold Increase in Production of Active Subtilisin E in Escherichia Coli (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 948-950 
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    Notes: [Auszug] Denatured pro-subtilisin accumulated as aggregates in the Escherichia coli periplasmic space when pro-subtilisin was fused to the OmpA signal peptide using a high expression secretion vector, pIN-III-ompA, and only a small fraction of pro-subtilisin was properly folded to produce active subtilisin. ...
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    Fermentor and Bioreactor Products (1988)
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    Nature biotechnology 6 (1988), S. 964-965 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Animal cell bioreactors offered by Whatman Biosystems (Clifton, NJ and Kent, U.K.) support the growth of both anchorage-dependent and non-anchorage-dependent animal cell lines. Whatman's cell culture systems meet stringent containment and contamination control standards. Write in 801 on Reader ...
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    New Products (1988)
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    Nature biotechnology 6 (1988), S. 966-969 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Zymate II sample handling system from Zymark Corp. (Hopkinton, MA) robotically aliquots samples, adds reagents, mixes, centrifuges, and injects HPLC samples. The company offers a free trial of an 11-minute video showing Zymate II in action. Write in 601 on Reader Service Card Gas ...
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    Trends in Contract Cell Culture (1988)
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    Nature biotechnology 6 (1988), S. 961-963 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] More than ever, the subtleties of moderate- to large-scale mammalian and hybridoma cell culture are creating a need for expert services. A biopharm company's ultimate goal may be in-house production, but long before that becomes practical it must have test quantities of recombinant proteins, made ...
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    Free Literature (1988)
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    Nature biotechnology 6 (1988), S. 970-970 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] A full-color brochure from Nalge (Rochester, NY) features the complete line of Nalgene™ syringe filters and offers free samples of products for small-volume filtration, ultracleaning, and sterilization. Write in 703 on Reader Service Card Laboratory News from V A Howe (London) gives the ...
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    Announcements (1988)
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    Nature biotechnology 6 (1988), S. 972-972 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] September Meetings Sept. 7–11. 7th Cold Spring Harbor Meeting on Cancer Cells: The Molecular Diagnostics of Human Cancer. Cold Spring Harbor, NY. Info: Meetings Coordinator, CSHL, Cold Spring Harbor, NY 11724 Sept. 11–16. International Congress by EUCARPIA on Genetic Manipulation in ...
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    Biotechnology's First Turning Point—and its Next (1988)
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    Nature biotechnology 6 (1988), S. 984-984 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Environmental biotechnology's most violent moment—and perhaps its most significant—is but a year past. In the early morning hours of April 24, 1987, self-proclaimed “Mindless Thugs Against Genetic Engineering” ripped hundreds of strawberry plants from the soil of Contra ...
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    New Alliances, Approvals, And Funding (1988)
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    Nature biotechnology 6 (1988), S. 750-751 
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    Notes: [Auszug] Joint Ventures. New agreements between U.S. and non-U.S. companies attest to the continuing advantages of such deals for both sides. Thanks to a shorter approval cycle for new drugs in Europe, for example, Cetus will be able to market its IL-2 in Europe by early '89, a year earlier than in the ...
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    Principles Emerging for Deliberate Release (1988)
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    Nature biotechnology 6 (1988), S. 753-755 
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    Notes: [Auszug] WASHINGTON, D.C. and CARDIFF, Wales—Just a few years ago, virtually no one felt comfortable trying to formulate general principles for releasing genetically engineered organisms into the environment. This is no longer the case, however, as was clearly demonstrated at the First International ...
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    Optimization of Parameters in a DNA Sequenator Using Fluorescence Detection (1988)
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    Nature biotechnology 6 (1988), S. 816-821 
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    Notes: [Auszug] We have developed an automated DNA sequenator using a real-time fluorescence detection method, and achieved excellent sensitivity and rapid analysis by optimizing operating conditions. The sequenator uses unicolor labeling and four-track electrophoresis. Fluoresceine isothiocyanate(FITC)-labeled ...
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    Human B-Cell Stimulatory Factor-2 Expressed in Escherichia Coli (1988)
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    Nature biotechnology 6 (1988), S. 806-809 
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    Notes: [Auszug] Human B-cell stimulatory factor-2 (BSF-2/ IL-6) is an important cytokine regulating the growth and differentiation of cells as diverse as lymphocytes, hepatocytes, and neurons. Recently its aberrant expression has been correlated with several diseases. Starting with a previously isolated cDNA clone ...
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    Immunomodulatory Components Present in IMREG-1, an Experimental Immunosupportive Biologic (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 810-815 
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    Notes: [Auszug] Human leukocyte dialysates contain substances capable of affecting human immune function. A low molecular weight subfraction derived from human leukocyte dialysates, IMREG-1, has been shown to enhance cell mediated immunity, and is under clinical evaluation as an immunosupportive agent in AIDS/ARC ...
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    Haploid Plants from Tissue Culture: New Plant Varieties in a Shortened Time Frame (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 684-690 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Specialized plant tissue culture methods have enabled the production of completely homozygous breeding lines from gametic cells in a shortened time frame compared to conventional plant breeding. Plants from gametic cells of an F1 hybrid represent a gametic array each having a different genetic ...
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    Wood Hydrolysis by Cellulomonas Fimi Endoglucanase and Exogiucanase Coexpressed as Secreted Enzymes in Saccharomyces Cerevisiae (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 713-719 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The enzymatic hydrolysis of cellulose to glucose requires endo-β-1,4-glucanase, exo-β-1,4-glucanase and β-glucosidase. To engineer cellulolytic properties into the yeast Saccharomyces cerevisiae we have constructed a plasmid containing two Cellulomonat fimi cellulase genes, cenA ...
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    Mapping of a Protective Epitope of Pertussis Toxin by In Vitro Refolding of Recombinant Fragments (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 709-712 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Antigenic determinants are often composed of discontiguous polypeptide segments, adjacent on protein surfaces, which are difficult to map by conventional techniques. Here we show that although monoclonal antibodies did not recognize recombinant molecules containing only the aminoterminal or only ...
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    New Products (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 729-733 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Applied Biosystems' Analytical Division (Ramsey, NJ) offers a new diode array absorbance detector for HPLC. The BAS 1000S performs spectral scans with a sensitivity of 0.002 AUFS with under 1 percent noise under flow conditions. Scientists can monitor the unit's four independent output channels ...
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    Erratum (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 734-734 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: We wish to call attention to an error in our paper entitled “A Modified Human Tissue Plasminogen Activator with Extended Half-Life In Vivo” (Bio/Technology 5:953–958, Sept. '87). In the paper, we described a mutant protein reported to have an asparagine mutated to ...
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    Free Literature (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 735-735 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A full range of single and multiple wavelength ultraviolet lights, lamps, and fluorescent tables for applications including bacterial inactivation, DNA visualization, and phototoxicity studies are shown in a colorful booklet from Vilber Lourmat (Marne La Vallée, France). Photographic dark ...
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    Improved DNA Analysis May Be Mixed Blessing (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 459-460 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] COLD SPRING HARBOR, N.Y.—No matter where one looks these days, someone always seems to be waving around the results of a clinical DNA analysis. Methods once confined to research laboratories have flowed smoothly into clinical labs, and a veritable flood of practical applications could soon ...
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    First Crystalization for a Ligninase (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 460-460 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In this issue of Bio/Technology, Jan-Derk G. Smit, Armin Fietchter, and their colleagues at the Swiss Federal Institute of Technology (Zurich) and the Biozentrum (Basel) report the first crystalization of a ligninase. Lignin is the most abundant aromatic polymer in the world, but the details of its ...
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    A Tough Row to Hoe for Virus Resistance (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 464-464 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The potential commercial value of transgenic plants exhibiting virus tolerance or resistance is difficult to estimate. Market size approximation is confounded by several factors, most notably difficulties in quantifying crop losses from virus under field conditions, and the lack of extensive ...
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    FDA: Devices, Divisions, and Discussions (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 467-467 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—The Food and Drug Administration (FDA) has approved many more biotech-derived diagnostics than it has drugs or biologics, yet the concerns and controversies seem reserved for therapeutics. Nevertheless, some diagnostics—officially known as medical devices—can ...
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    Making Chimeric Antibodies Even More Human (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 468-468 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Researchers are anxiously awaiting clinical results of therapy using chimeric monoclonal antibodies (which contain rodent antigen-binding sites but are otherwise of human origin). Nevertheless, U.K. commercial attention is already turning toward even more extensively ...
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    Helpful Hints from the FDA Commissioner (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 470-470 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BOSTON—“The biggest trap that you can fall into is improper validation,” warned U.S. Food and Drug Administration (FDA) commissioner Frank E. Young at the Massachusetts Biotechnology Council annual meeting held here recently. “Consult with us early in order to design and ...
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    Genentech's Busy Lawyers (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 472-472 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SOUTH SAN FRANCISCO—Biotech's premier R&D company is also its premier litigator. But Genentech has yet to repeat its scientific success in the courtroom: The firm has lost initial decisions in both a U.S. suit over factor VIII and a U.K. suit over tissue plasminogen activator (t-PA). And ...
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    Xenova Blends Old with New (1988)
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    Nature biotechnology 6 (1988), S. 473-473 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SLOUGH, U.K.—“Our main competitor is Merck,” proclaims Louis Nisbet, R&D director of Xenova Ltd., “not Celltech.” For a new biotechnology company with a staff of just 25, this statement seems little short of ludicrous. But as an indication of Xenova's scientific ...
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    Scale–Up: How Big is Big Enough? (1988)
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    Nature biotechnology 6 (1988), S. 479-485 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In scaling up to produce substantial quantities of a recombinant protein or a monoclonal antibody—sufficient for clinical trials and marketing—how much is enough? And how much pilot-plant or production hardware will be needed to make it? At one time, nobody involved in biotechnology ...
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    Cracking Open Marine Algae's Biological Treasure Chest (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 487-492 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Oceans cover 70 percent of the world's surface. Although the marine environment is vast, it is also harsh and often inaccessible. Man may no longer be a hunter-gather on land, but he certainly remains one at sea. The commercial future of harnessing the ocean's organisms and their unusual ...
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    U.K. Manpower Shortage (1988)
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    Nature biotechnology 6 (1988), S. 474-474 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—A survey of manpower, education, and training in U.K. biotechnology companies* has exposed both immediate and long-term concerns about whether the supply of suitable recruits will keep pace with the demand. Already in short supply are protein chemists, immunologists, plant ...
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    Fighting the Financing Frenzy: What Next for Biotechnology Companies? (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 495-501 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Last October 19, the chaos of the wild West prevailed in the financial markets. In the ensuing shoot-out on Wall Street, biotechnology stocks got caught in a cross fire. Already under-performing the S&P 400 by about 15 percent during the first three quarters of 1987, these issues were gunned ...
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    ASB: An Umbrella (1988)
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    Nature biotechnology 6 (1988), S. 597-597 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: The ASB is a terrific suggestion. Perhaps the most effective function of the association would be to act as an umbrella society for the various technical societies. This might be a difficult structure to build because of the individual aspirations of each society, but the ASB could ...
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    ASB: Home for Strangers (1988)
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    Nature biotechnology 6 (1988), S. 592-592 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: I not only approve of the suggestion to create an American Society for Biotechnology, I am very optimistic about the outcome. There are, of course, other scientific societies with biotechnology divisions. Although these serve a purpose in bringing together those researchers ...
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    ASB: Educational Role (1988)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 6 (1988), S. 597-597 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: “And now, what about leaving things just as they are? That is what most people vote for doing. Even when they don't like what they are accustomed to, they dread change, lest it should make matters worse. They are what they call Conservative, though it is only fair to add that ...
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    How Biotech is Dealing with its Nitrogen Fixation (1988)
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    Nature biotechnology 6 (1988), S. 383-385 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In 1984, Commercial Biotechnology: An International Analysis predicted that “genetically manipulated Rhizobium may be fieldtested soon.” On March 10, 1988, BioTechnica International (Cambridge, MA) finally received the first U.S. permission to field-test a recombinant Rhizobium ...
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    Models for Integrating Biotech into Crop Improvement Programs (1988)
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    Nature biotechnology 6 (1988), S. 387-392 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Integrating new technologies into conventional plant-breeding programs warrants particular attention if the potential of these technologies to improve productivity and stability of crops is to be realized. The sizeable investment required to launch biotechnology efforts will result in few practical ...
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    Please Release Me (1988)
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    Nature biotechnology 6 (1988), S. 749-749 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Now is the winter of our discontent made glorious summer. Messengers come from every quarter bearing tidings of what seem to be fundamentally new attitudes towards the free release (or planned introduction, or whatever the season's newphemism may be) of genetically engineered organisms: the ...
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    Europe Getting into the HIV-Testing Act (1988)
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    Nature biotechnology 6 (1988), S. 761-761 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Compared with the large number of U.S. companies in the highly competitive business of blood-screening tests for human immunodeficiency virus (HIV) (see Bio/ Technology 6:259–264, Mar. '88), European firms are still few. In technical terms, however, they seem to be holding their ...
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    A Controversial Test Case (1988)
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    Nature biotechnology 6 (1988), S. 762-762 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C. and CARDIFF, Wales—A rabies vaccine trial conducted in 1986 at a Pan American Health Organization (PAHO) test facility in Argentina has been controversial from the start (see Bio/Technology 5:13, Jan. '87). Delivering a paper at REGEM 1 on behalf of Jose La Torre from ...
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    Genentech's Vienna Venture (1988)
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    Nature biotechnology 6 (1988), S. 763-763 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] VIENNA—Executives from Genentech (South San Francisco, CA) and Boehringer Ingelheim (Ingelheim, FRG) were thick on the ground in Vienna at the end of May for the opening of their joint Research Institute of Molecular Pathology (IMP). Set up to generate product ideas for cancer therapy from a ...
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    Criteria for Low-to No-Risk Field Trials (1988)
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    Nature biotechnology 6 (1988), S. 762-762 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] PARIS—Many field trials involving the deliberate release of organisms into the environment are designed to be done under conditions that present negligible or low risks. Establishing the actual scientific criteria for such experiments is a major priority of the Organisation for Economic ...
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    Japan Roundup (1988)
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    Nature biotechnology 6 (1988), S. 764-764 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Scientists at Hasegawa Koryo Inc., working in collaboration with Hiroshi Orui at Tohoku University, have developed a method for the complete chemical synthesis of the AIDS therapeutic AZT (azidothytnidine). Currently, AZT is synthesized from deoxythymidine isolated from DNA, an expensive starting ...
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    Release Regulators Refining Their Roles (1988)
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    Nature biotechnology 6 (1988), S. 764-764 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] WASHINGTON, D.C.—The smooth operation of the Environmental Protection Agency (EPA) is essential for all groups seeking U.S. approval of experiments to deliberately release genetically engineered microorganisms. And at its May meeting, EPA's Biotechnology Science Advisory Committee (BSAC) ...
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    Large-Scale In Vitro Hybridoma Culture: Current Status (1988)
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    Nature biotechnology 6 (1988), S. 784-786 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Despite the intense international interest in producing monoclonal antibodies (MAbs) by in vitro hybridoma culture, even some of the most sophisticated users are unaware of the basic schematization of reactor types, homogeneous and heterogeneous systems, and of the bearing this schema has on the ...
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    Protecting Non-U.S. Research in the United States (1988)
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    Nature biotechnology 6 (1988), S. 791-792 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Under U.S. patent laws, biotechnology companies whose inventions are created in non-U.S. research facilities suffer from a serious disadvantage: their inventions are not afforded the same rights as those developed in U.S. research facilities. Failure to recognize this inequity can cost a company ...
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    Japan Roundup (1988)
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    Nature biotechnology 6 (1988), S. 644-644 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] A novel polypeptide antibiotic that is effective against a wide variety of fungi has been discovered at the Biological Sciences Research Laboratories of Lion Corp. (Tokyo). Lion Corp., a major detergents and toiletries manufacturer, has recently diversified into Pharmaceuticals. Isolated from a ...
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    Ailing I.P.O. Spells Bad News for Biotech (1988)
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    Nature biotechnology 6 (1988), S. 651-651 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] NEW YORK—Never send to know for whom the bellwether tolls. It tolls for thee…. In this case, the initial public offering (IPO) of NeoRx (Seattle, WA) had been labeled the bellwether for bio-tech public financings. And, unfortunately, it's tolling pretty loudly. According to NeoRx ...
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