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  • Oxford University Press  (3,927)
  • National Academy of Sciences  (1,893)
  • Nature Publishing Company
  • 1985-1989  (6,140)
  • 1985  (6,140)
Collection
Years
  • 1985-1989  (6,140)
Year
  • 1
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Injection of recombinant chicken or bovine growth hormone into juvenile coho salmon (Oncorhynchus kisutch) resulted in significant dose dependent increases in growth rate and also improved feed conversion. Weight gain in fish receiving 5 μg/g/week recombinant chicken or bovine growth hormone ...
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  • 2
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    Nature biotechnology 3 (1985), S. 649-651 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Immobilized thermostable glucose dehydrogenase from the mesophile Bacillus cereus has been prepared and used to catalyze the regeneration of NAD(P)H in enzymatic syntheses. The thermal stability of the immobilized enzyme in aqueous buffer containing NaCl is about 50,000 times that of the free ...
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  • 3
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    Nature biotechnology 3 (1985), S. 534-538 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] When biotech executives muse about applying their arts to the production of odors, the fragrance they talk about most is jasmine. Wholesaling at about $5,000 per kilogram, this exotic aroma is just the sort of high-value, low-volume product dear to biotechnology. Forget that the total world ...
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  • 4
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    Nature biotechnology 3 (1985), S. 540-546 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In 1981 a group of local executives laid grand plans for a biotechnology park in Worcester, MA, directly across from the University of Massachusetts Medical Center. Today, there are still grand plans for the biotech park in Worcester, but the grounds bordering the Medical Center remain lush, ...
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  • 5
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    Nature biotechnology 3 (1985), S. 555-560 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Protoplasts from plants with different organelle-types were fused in order to monitor the fate of mixed cytoplasms in plants regenerated from fused protoplasts. Protoplasts of Nicotiana tabacum (tobacco) were fused with two experimental lines containing N. tabacum nucleus but containing the ...
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  • 6
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We review a current methodology which analyzes quantitative scattering data from Scanning Transmission Electron Microscopy to establish footprints—positions of DNA-binding proteins on cloned genes—and mass distributions for the bound protein. Recognition by computer of the DNA path and ...
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  • 7
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    Nature biotechnology 3 (1985), S. 475-480 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The 700 series microelectrode amplifiers for intracellular recording using fluid-filled, high impedance glass microelectrodes are available from World Precision Instruments (New Haven, CT). Features include ultra-stable, gold-plated input probes, low noise, negative capacitance, and electrode test ...
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  • 8
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    Nature biotechnology 3 (1985), S. 481-483 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The new laboratory consumables catalog and reference guide with a free labmarker is available from Elkay Products, Inc. (Shrewsbury, MA). Elkay 85 is 44 color pages of the company's comprehensive line of molded and extruded plastic disposables, including over 40 new products including sterile ...
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  • 9
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    Nature biotechnology 3 (1985), S. 485-485 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] June 2–6. Tissue Culture Association Annual Meeting. New Orleans, LA. Info: Frederick H. Kasten, Dept. of Anatomy, Louisiana State Medical Center, 1100 Florida Ave., New Orleans, LA 70119 June 2–7. Mechanisms of DNA Damage and Repair: Implications for Carcinogenesis and Risk ...
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  • 10
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    Nature biotechnology 3 (1985), S. 281-281 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] “Quantum pharmacology” first came into my ken about ten years ago. Along with “tissue culture” and “computer modeling, ” the term was then being brandished as an instantaneous answer to the need for animals in medical research and toxicity testing. By embracing ...
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  • 11
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    Nature biotechnology 3 (1985), S. 279-279 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The Recombinant DNA Advisory Committee (RAG) of the National Institutes of Health is the new biology?s monument to its own foresight and probity. The mechanism has served long and well, but it was never intended to cover the teeming diversity of commercial biotechnology. Thus it was inevitable that ...
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  • 12
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    Nature biotechnology 3 (1985), S. 285-285 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Cetus Corp. (Emery-ville, CA) has decided not to renew its license to the Stanford Cohen-Boyer patents. Albert Halluin, general patent and trademark counsel for Cetus, notified Stanfords patent technology licensing office of this decision on January 25. The following Tuesday Harold ...
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  • 13
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    Nature biotechnology 3 (1985), S. 287-289 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—A significant number of biotechnology companies are applying for—and getting—government funds to support basic research. The government-wide budget for Small Business Innovation Research (SBIR) grants is $225 million, of which roughly 25 percent goes to bio tech. ...
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  • 14
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    Nature biotechnology 3 (1985), S. 289-289 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] VIENNA—The architects of the International Centre for Genetic Engineering and Biotechnology (IC-GEB) face an interesting dilemma: how to establish the credibility of the ICGEB as a center of excellence before there is either faculty or facility. The center's newly created Panel of Scientific ...
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  • 15
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    Nature biotechnology 3 (1985), S. 317-320 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Yeast cells are genetically engineered to synthesize and assemble hepatitis B surface antigen particles containing 55 additional amino acids encoded by the hepatitis B virus preS gene. These particles are composed of a 28,000 dalton protein and efficiently bind polymerized human albumin. Antibodies ...
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  • 16
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A new approach for antigen presentation and polyvalent vaccines is tested. The idea is to recombine the gene of a second immunogen with that of hepatitis B surface antigen so that the second immunogen is assembled into, and presented on the surface of the HBsAg particle. We describe here the ...
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  • 17
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    Nature biotechnology 3 (1985), S. 337-356 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Flow cytometry combines many of the advantages of microscopy and biochemical analysis in a single high precision technique for rapid phenotypic analysis and sorting of individual cells, microorganisms and cell organelles. Flow cytometry has evolved over the past twenty five years from a few ...
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  • 18
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    Nature biotechnology 3 (1985), S. 329-335 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] This paper outlines a system for data base management of a recombinant DNA bank that achieves three goals. First, it establishes a unique definition for each genetic element cloned in the laboratory; second, it documents precisely the construction of each hybrid molecule; and third, it establishes ...
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  • 19
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    Nature biotechnology 3 (1985), S. 358-358 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Enzyme Technology. Edited by R. M. Lafferty. Pp. 314. ISBN 3-540-12479-9. $46.50. (Springer-Verlag, Berlin-Heidelberg: 1983). This book represents the proceedings of the Illrd Rotenburger Fermentation Symposium held in 1982 in Kassel. Enzyme technology was the main subject of the symposium ...
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  • 20
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    Nature biotechnology 3 (1985), S. 183-183 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The patchwork presented by the U.S. Office of Science and Technology Policy (OSTP) as its “Proposal for a Coordinated Framework for Regulation of Biotechnology” is an ungainly creature. The authors have cobbled up a matrix of existing statutes that might conceivably cover biotechnology, ...
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  • 21
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    Nature biotechnology 3 (1985), S. 185-185 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] “There's no place for serendipity nowadays,” announced a biochemist on the edge of a noisy group huddled in the corner. The occasion was a meeting held in London recently by Online Conferences to explore “Bioscience Futures.” Around sundown on the first day, devoted entirely ...
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  • 22
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    Nature biotechnology 3 (1985), S. 187-191 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—In their quest for more efficient production, hybridoma researchers continue to seek new ways to fuse cells in electric fields. The standard techniques of cell fusion—using inactivated viruses or chemicals such as polyethylene glycol (PEG)—prove inefficient and ...
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  • 23
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    Nature biotechnology 3 (1985), S. 253-254 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] When very weak electric currents of the order of 1 microamp were passed between the tissue and the culture medium, dramatic increases in growth were recorded for tobacco callus. The effect was dependent on the direction of the current. When the callus was made negative, the growth rate was ...
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  • 24
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    Nature biotechnology 3 (1985), S. 259-261 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The first product from Gen-Probe (San Diego, CA) is a mycoplasma detection kit that allows rapid detection of this bacterium which infects tissue culture samples and the human respiratory tract. Designed for research and bio-industrial laboratories, the procedure uses DNA probe technology to cut ...
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  • 25
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In greenhouse and laboratory experiments, a plant bioregulator 2-diethylaminoethyl-3,4-dichlorophenylether (DCPTA) appears to have the potential for biochemical manipulation of plant growth. As compared with control plants, photosynthesis of DGPTA-treated plants was increased about 21%, and biomass ...
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  • 26
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    Nature biotechnology 3 (1985), S. 263-263 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Fisher Apparel from Fisher Scientific (Pittsburgh, PA) shows the company?s line of protective apparel. Many of the models are resistant to tear, puncture, abrasion, and flame, are antistatic, and are impenetrable to wet chemicals and to air. Write in 701 on Reader Service Card Catalog 85 from ...
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  • 27
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    Nature biotechnology 3 (1985), S. 265-265 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] APRIL MEETINGS April 1–2. Seminar on Advances in Biotechnology. Moscow, U.S.S.R. Info: Marisha Zeffer, Chromatronix, 2300 Leghorn St., Mountain View, CA 94043 April 1–2. Bioscience Futures. Philadelphia, PA. Info: Tazewell Wilson, Online Conferences, 989 Ave. of the Americas, New ...
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  • 28
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    Nature biotechnology 3 (1985), S. 272-272 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A recent Wall Street Journal article (“Attempts to Regulate Gene Splicing Harmony Between U.S., Industry,” Jan. 9, 1985) noted a remarkably cooperative spirit between the regulators and the regulated in the first stages of commercial biotechnology's development. Establishing such ...
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  • 29
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    Nature biotechnology 3 (1985), S. 101-101 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Announcement of a Nobel Prize to Cesar Milstein and Georges Koehler for devising monoclonal antibodies must have stirred up more diverse nationalistic sentiments last fall than any other Nobel award for some considerable time. When (together with the Dane Niels Jerne) they received this ultimate ...
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  • 30
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    Nature biotechnology 3 (1985), S. 103-104 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—First there was Humulin™. Then there was NutraSweet™. These well-known products of the biotechnology industry are joined by only a handful of others in the marketplace. Analysts, businessmen, corporate officers, and even research scientists had predicted a flood of ...
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  • 31
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    Nature biotechnology 3 (1985), S. 105-107 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BOSTON, Mass.—Genetics Institute, located here, has purchased a 28–29 percent equity stake in United AgriSeeds (Champaign, IL), an agricultural research and seed distribution firm. As part of the arrangement, United AgriSeeds (UAS) will sponsor research at Genetics Institute (GI) on ...
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  • 32
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    Nature biotechnology 3 (1985), S. 109-109 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Researchers at Tokyo Institute of Technology, Nitto Electric Industrial Co., and RIKEN (The Institute of Physical and Chemical Research) have developed a new, efficient method for cultivating mold fungi by adding a urethane foam to the culture medium. The new method may have pharmaceutical and ...
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  • 33
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    Nature biotechnology 3 (1985), S. 109-109 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Monsanto Agricultural Products Co. (St. Louis, MO) has notified the U.S. Environmental Protection Agency (EPA) that it intends to begin field testing a recombinant bacterium— perhaps as early as April. The organism—a strain of corn-root-colonizing Psuedomonas ftuorescens—has been ...
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  • 34
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    Nature biotechnology 3 (1985), S. 110-110 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Pessimistic venture capitalists met optimistic engineers at the recent “Investment in Biotechnology” conference here. The venture capitalists stressed the need for realism; the engineers stressed the need for pilot plants. Although the honeymoon between venture capitalists ...
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  • 35
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    Nature biotechnology 3 (1985), S. 113-113 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Thiobacillus ferroxidans could help reduce acid rain in the U.K. and cut back the politically troublesome export of this pollutant to other parts of Europe. According to studies by Tony Atkins and colleagues at University College (Cardiff) and North Staffordshire Polytechnic ...
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  • 36
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    Nature biotechnology 3 (1985), S. 113-113 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WARWICK, England—A year after Mrs. Thatcher announced that the National Research Development Group (the NRDC, now part of the British Technology Group or BTG) was to lose its “first rights” claim to discoveries made on U.K. campuses, the universities are still in limbo, unsure ...
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    Nature biotechnology 3 (1985), S. 115-115 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Early in 1984, the Biotechnology Unit of the U.K. Department of Trade and Industry (DTI) commissioned John Brown Engineers and Constructors Ltd. to survey “The Future Market for Process Plant for Biotechnology” in order to assist British industry in identifying future ...
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    Nature biotechnology 3 (1985), S. 116-116 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] WASHINGTON, D.C.—In November 1984 the National Aeronautics and Space Administration awarded nearly $3 million in grants for the development of two bioprocessing research centers. NASA set 1992 as the target date for construction of its $8 billion manned space station. As the ...
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    Nature biotechnology 3 (1985), S. 117-117 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] TORONTO—Discussion about the sorry state of Canadian venture capital dominated the recent meeting here on “Investing in Canadian Biotechnology.” While entrepreneurs blamed venture capitalists for being afraid to invest in biotechnology, the financiers countered that Canadian ...
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    Nature biotechnology 3 (1985), S. 119-125 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Five years ago many researchers believed that albumin would be the first blood-plasma protein produced by genetic engineering. Now, with the recently announced cloning and expression of factor VIII, it seems clear that this fraction, clotting f\actor, will be the first to fall to the wonders of ...
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    Nature biotechnology 3 (1985), S. 126-128 
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    Notes: [Auszug] What makes biotechnology exciting? To Michael A. Wall, founder and chairman of Centocor (Malvern, PA), it is the opportunity to participate in the commercial devel opment of a technology from the ground up. Wall has positioned his company at the leading edge: he is only interested in products that ...
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    Nature biotechnology 3 (1985), S. 129-130 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Our aim,” says Ola Carlsson, Pharmacia's director of public affairs, “is to become one of the main suppliers of basic products, methods, systems, and processes for the separation, purification, and analyses of biomolecules, cells, and cell particles.“ The company, which started ...
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    Nature biotechnology 3 (1985), S. 135-140 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] In this review we summarize the current knowledge of polypeptide growth factors, their receptors and oncogenes. Recent studies indicate that oncogenes are linked to growth factors and to growth factor receptors, suggesting that these molecules participate in the proliferation of normal and ...
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    Nature biotechnology 3 (1985), S. 143-149 
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    Notes: [Auszug] The process by which free-living Rhizobium forms nitrogen-fixing nodules on the roots of leguminous plants involves the induction and repression of a number of bacterial genes. To help identify these genes and to determine their mode of regulation, we have transposed the E. coli lac operon, minus ...
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    Nature biotechnology 3 (1985), S. 155-160 
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    Notes: [Auszug] Hard and softwoods were pretreated by mild acid hydrolysis and their pore size distribution determined. Regardless of the substrate, the initial rate of hydrolysis using cellulase from Trichoderma reesei is linearly correlated with the pore volume of the substrate accessible to a nominal diameter ...
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  • 46
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    Nature biotechnology 3 (1985), S. 151-154 
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    Notes: [Auszug] High-level expression of bovine growth hormone in Escherichia coli results in the formation of distinct cytoplasmic granules that are visible with the phase-contrast microscope. These granules were examined by transmission and scanning electron microscopy. Intact granules were isolated from crude ...
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    Nature biotechnology 3 (1985), S. 161-163 
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    Notes: [Auszug] A Corynebacterium diphtheriae strain, containing two copies of the corynephage β45 genome integrated into its chromosome, has been isolated and characterized. This strain produces and secretes into the medium large amounts of diphtheria toxoid CRM45, a non toxic, prematurely terminated ...
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    Nature biotechnology 3 (1985), S. 165-167 
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    Notes: [Auszug] Peptides International (Louisville, KY) introduces the Syn-Thor 2000 solid phase peptide synthesizer, with computer controlled pressurization and reagent delivery volumes, self-cleaning lines, and separately programmable wash steps to eliminate cross contamination. The Syn-Thor 2000 is compatible ...
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    Nature biotechnology 3 (1985), S. 168-168 
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    Notes: [Auszug] A new laboratory guide for use in stock culture maintenance is available from the American Type Culture Collection (Rockville, MD). The 98 page handbook contains over 1000 media formulations used at ATCC to propagate strains of algae, bacteria, cell lines, fungi, and protozoa. Step-by-step ...
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    Nature biotechnology 3 (1985), S. 169-169 
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    Notes: [Auszug] MARCH MEETINGS March 3–8. American Society for Microbiology Annual Meeting. Las Vegas, NV. Info: Richard A. Bray, Meetings Dept., ASM, 1913 I St., NW, Washington, D.C. 20006 March 17–29. NATO-ASI Meeting on Recent Developments in Biotechnology. Tróia, Portugal. Info: ...
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    Nature biotechnology 3 (1985), S. 176-176 
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    Notes: [Auszug] Until recently, biotechnology in Japan was mainly a matter of fermentation—in brewing and the manufacture of pharmaceuticals and organic chemicals. However, recent strides in molecular biology and molecular immunology make us confident that the technology will play a key role in production ...
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    Nature biotechnology 3 (1985), S. 95-95 
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    Notes: [Auszug] To the editor: I would appreciate your publishing this letter to correct a citation given by James L. Dwyer of Millipore Corp. (Bedford, MA) in his article, “Scaling Up Bio-Product Separation with High Performance Chromatography,” which you published in November. Dr. Dwyer cites a ...
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    Nature biotechnology 3 (1985), S. 95-95 
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    Notes: [Auszug] To the editor: I was surprised to read in your article entitled “Engineering herbicide tolerance: When is it worthwhile?” (November, 1984) that my colleagues and I had successfully transformed tobacco with a bacterial gene. We were reported to have introduced a mutant allele of the ...
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    Nature biotechnology 3 (1985), S. 95-95 
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    Notes: [Auszug] To the editor: In the November 1984 issue, the article entitled “Big Resources for Small Computers” mentioned several genetic information sources and databases, among them EIC/Intelligence's “Telegen.” We'd like to clarify a point. Telegen does provide the full-text for ...
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    Nature biotechnology 3 (1985), S. 95-95 
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    Notes: [Auszug] To the editor: Could you explain to me why your biotechnology stock reports are no longer given. I found the BIO/TECHNOLOGY tables by far the most useful I have seen—far more so than the Nature list—and I would like to see their ...
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    Notes: [Auszug] The “Stock Prices of Selected Biotechnology Stocks” ran in our January issue (which crossed Mr. Bunting's letter in the mail) and will continue to run from time to time. The Index is useful as a barometer of Wall Street's attitudes toward biotechnology and as a gauge of public ...
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    Notes: [Auszug] To the editor: The article “Biotechnology touches the forest” by Tabitha M. Powledge in the September issue was very well written and clearly summarized the presentations at the International Symposium of Recent Advances in Forest Biotechnology held June 10–13, 1984, in Traverse ...
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    Notes: [Auszug] In the article titled “Molecular Biology and Ecology of Diazotrophs Associated with Non-Leguminous Plants” by Claudine Emerich in the November issue (2:967–978), pages 969 and 970 were inadvertently ...
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    Nature biotechnology 3 (1985), S. 99-99 
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    Notes: [Auszug] Gene therapy, some argue, is not properly the province of biotechnology at all, as though the techniques of genetic engineering became somehow different in kind when applied to human marrow stem cells rather than Escherichia coli. Yet the barest whisper of an ability to genetically engineer humans ...
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    Nature biotechnology 3 (1985), S. 1045-1045 
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    Notes: [Auszug] Recent discussions of free release brought back memories of a college classmate who refused to accept the idea that a solid object—a gamma particle or even, say, a human body—could spontaneously “tunnel” through a solid barrier—the nuclear boundary or, say, the ...
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    Nature biotechnology 3 (1985), S. 1046-1046 
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    Notes: [Auszug] Usually, it's a ridiculously cluttered slide that sets me off. (“Sorry about this…I don't suppose people at the back will be able to see.”) At other times the air-conditioning or an underwhelming monotone is to blame. Whatever the reason, day-dreaming at scientific meetings is a ...
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    Nature biotechnology 3 (1985), S. 1049-1051 
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    Notes: [Auszug] Scientists at Texas Tech University (Lubbock) and Ciba-Geigy (Research Triangle Park, NC) have made separate advances in research on improved cotton varieties. Both firsts stem from attempts to regenerate whole cotton plants from cell culture. Texas Tech's Joseph R. Goodin, Jerry D. Berlin, and ...
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    Nature biotechnology 3 (1985), S. 1052-1052 
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    Notes: [Auszug] In recent years scientists have focused considerable attention on the development of transformation systems for higher plants. In 1980 M. R. Davey and coworkers at the University of Nottingham showed that dicotyledenous plant protoplasts could be directly transformed by the introduction of Ti ...
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    Nature biotechnology 3 (1985), S. 1054-1054 
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    Notes: [Auszug] WASHINGTON, D.C.—The U.S. Office of Technology Assessment (OTA) has initiated a project called “New Developments in Biotechnology.” The 28-month assessment, which began officially on October 1, will produce technical memoranda, background papers, and small reports, plus an overall ...
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    Notes: [Auszug] TORONTO—The recent discovery by scientists at this city's Hospital for Sick Children of a chromosome site close to the gene responsible for cystic fibrosis is the first practical application of an effort by Massachusetts scientists to construct a human gene map. Scientists at Collaborative ...
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    Notes: [Auszug] NEW YORK—It's been a long wait, but the Bio/Technology Index of Specialty Firms finally climbed back over the 1000 mark where it was set in July of 1983. In fact, the index rocketed all the way to 1192 as of November 13, up from 966 a month earlier. In a generally record-setting market, the ...
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    Nature biotechnology 3 (1985), S. 1059-1060 
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    Notes: [Auszug] NEW YORK—At long last, “everything under the sun made by man” (a phrase coined by the 82nd Congress) is potentially patentable. In October, the United States Patent and Trademark Office (PTO) reversed its 50-year stance, and ruled that plants can be patented under the general ...
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    Nature biotechnology 3 (1985), S. 1062-1062 
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    Notes: [Auszug] The restructuring of Genex Corp. (Rockville, MD) continues as the company announced that it is laying off some 40 percent of its 146 employees and is consolidating operations into its Science and Technology Center. Genex says it will eliminate most of its proprietary programs in favor of performing ...
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    Nature biotechnology 3 (1985), S. 1062-1062 
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    Notes: [Auszug] WASHINGTON, D.C.—“There is no doubt in my mind that the Advanced Genetic Sciences experimental use permit is going to be subject to litigation,” said Steven Schatzow, director of pesticide programs at the U.S. Environmental Protection Agency (EPA). “But I don't intend to ...
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    Nature biotechnology 3 (1985), S. 1065-1067 
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    Notes: [Auszug] Barring yet another legal challenge, final approval for field-testing a recombinant organism could reach experimenters this season. If and when the way is cleared for responsible research in the real world, it will ring down the curtain on the most strident act in biotech's short history. Fear of ...
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    Nature biotechnology 3 (1985), S. 1070-1071 
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    Notes: [Auszug] Is there a European position on the deliberate release of engineered organisms into the environment? Unfortunately not, despite the efforts of the European Commission in Brussels—the administrator of the 12-nation European regulations on biotechnology. Not the least of the problems is that ...
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    Nature biotechnology 3 (1985), S. 1072-1072 
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    Notes: [Auszug] No Japanese group—public or private—has yet made any attempt to field-test a recombinant microbe. Most commercial research here centers on contained processes, especially fermentations for the pharmaceutical and chemical industries. Some applications to pest control, bacterial metal ...
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    Nature biotechnology 3 (1985), S. 1073-1078 
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    Notes: [Auszug] Pseudomonas syringae catalyzes the crystallization of supercooled water to form ice at temperatures approaching −1.5°C1. Ice nucleation active (INA) bacteria—in association with plant leaves—are the ice nuclei that initiate the ice formation that causes frost injury to ...
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    Nature biotechnology 3 (1985), S. 1081-1083 
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    Notes: [Auszug] A variety of strategies to stimulate biotechno-logical R&D are attracting the attention of researchers, entrepreneurs, and venture capitalists. State governments are including in their budgets allocations to improve the faculty and facilities of science programs in higher education institutions ...
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    Nature biotechnology 3 (1985), S. 1085-1085 
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    Notes: [Auszug] ENGLAND The Science and Engineering Research Council (SERC) has created a Biotechnology Directorate to coordinate research and training programs in biotechnology and to promote biotechnological research through partnerships between universities, polytechnics, and industry. SERC hopes to increase ...
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    Nature biotechnology 3 (1985), S. 1089-1098 
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    Notes: [Auszug] The renin-angiotensin and the kallikrein-kinin systems play important physiological roles including regulation of blood pressure and inflammation reactions. Our understanding of the structures, gene organizations and regulations of the enzymes and the peptide precursors in these systems has ...
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    Nature biotechnology 3 (1985), S. 1099-1103 
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    Notes: [Auszug] The efficiency of direct gene transfer to plant protoplasts has been increased more than 1000 fold over that previously reported. On the order of 2 percent of all colonies recovered without selection were transformed. The improvement was due to: treatment of protoplasts with a high voltage electric ...
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    Nature biotechnology 3 (1985), S. 1104-1106 
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    Notes: [Auszug] It has been found possible to achieve rapid enzymatic degradation of the cell wall of the apices of root hairs from a wide range of crop species. Thereby it is possible to expose plasma membranes with partial protoplast release whilst maintaining the functional integrity of the plant. This exposure ...
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    Nature biotechnology 3 (1985), S. 1107-1109 
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    Notes: [Auszug] Minute electric currents of the order of 1–2 microamps stimulate shoot differentiation up to 5-fold in tobacco callus cultures. The location of the first-formed shoots depends on the direction of the current. Similar stimulations of both root and shoot formation have been observed in wheat. ...
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    Nature biotechnology 3 (1985), S. 1110-1111 
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    Notes: [Auszug] Weighmaster from Applied Scientific Computers, Inc (Caguas, P.R.) inexpensively automates laboratory and production weighing. It includes all hardware and software necessary to interface with up to 16 different electronic balances for data collection, calculation and storage while producing hard ...
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    Nature biotechnology 3 (1985), S. 1112-1112 
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    Notes: [Auszug] An 8-page brochure offered by Savant Instruments (Farmingdale, NY) describes the Savant Speed Vac System which can be used with rotary evaporators, ultra-filtration devices and freeze dryers for reducing volume by evaporation of aqueous and/or organic solvents. Write in 700 on Reader Service Card ...
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    Nature biotechnology 3 (1985), S. 1113-1113 
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    Notes: [Auszug] JANUARY MEETINGS Jan. 15–17. First International Symposium on Preparative and Up Scale Liquid Chromatography. Paris. Info: Societe Francaise de Chemie, 250 rue Saint-Jacques, 75005 Paris, France Jan. 20–22. Bio/Technology Looks to the Next Decade. New Orleans, LA. Info: Nature ...
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    Nature biotechnology 3 (1985), S. 1120-1120 
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    Notes: [Auszug] I've stolen a movie title for this editorial because it neatly expresses the point that I want to make. Simply put, in the current brouhaha over commercial biotechnology—which agencies regulate what part? What safety tests are to be applied to which uses? Will the smaller venture companies be ...
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    Nature biotechnology 3 (1985), S. 1003-1007 
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    Notes: [Auszug] The ability to synthesize D-alanine is essential for the biosynthesis of cell walls of most bacteria. D-alanine is normally produced by racemization of L-alanine; in the absence of a functional alanine racemase, D-alanine must be provided for cell growth. An alanine racemase gene has been isolated ...
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    Nature biotechnology 3 (1985), S. 1008-1012 
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    Notes: [Auszug] A simple and rapid method for the detection of specific polymorphic restriction sites has been developed that utilizes restriction endonuclease cleavage of a synthetic, end-labeled oligonucleotide probe annealed in solution to the target genomic DNA sequence. The specificity of this method, which ...
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    Nature biotechnology 3 (1985), S. 1019-1019 
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    Notes: [Auszug] The Biology of Microorganisms. Edited by Arnold L. Demain and Nadine Solomon. Pp. 573. ISBN 0-8053-2451-8. $41.95. (Benjamin Cummings, Menlo Park, CA: 1985). Biology of Industrial Microorganisms is a one volume collection of reviews on the taxonomy, morphology, physiology, ecology, and ...
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    Nature biotechnology 3 (1985), S. 1014-1016 
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    Notes: [Auszug] A rapid and simple method for the recovery of DNA fragments from an agarose gel is described. It involves a ten minute centrifugation of the DNA-containing gel layered on a GeneScreen (NEN) or a Durapore (Millipore, GVWP 04700) membrane. With the latter a recovery of about 70 percent has been ...
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    Nature biotechnology 3 (1985), S. 1019-1021 
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    Notes: [Auszug] Practical Flow CytometryHoward M. Shapiro. Pp. 295. ISBN 0-8451-0243-5. $49.50. (Alan R. Liss, Inc., New York: 1985). This book is one of several just published or about to be published aimed at the rapidly expanding market of researchers interested in using flow cytometry as a tool in cell ...
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    Nature biotechnology 3 (1985), S. 1022-1022 
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    Notes: [Auszug] Advances in Biotechnological Processes, Volume 4. Edited by A. Mizrahi and A. L. van Wezel. Pp. 372. ISBN 0-8451-3202-2, $84.00. (Alan R. Liss, Inc., New York: 1985). The series of Advances in Biotechnological Processes, of which this is the fourth volume in two years, reflects the ...
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    Nature biotechnology 3 (1985), S. 1024-1024 
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    Notes: [Auszug] The Biotechnology Business: A Strategic Analysis. By Peter Daly. Pp. 155. ISBN 0-8476-7460-6. $22.50. (Frances Pinter Publishers, London: 1985). If you wake up on Christmas morning and find The Biotechnology Business: A Strategic Analysis waiting for you under the tree, do not despair. Its ...
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    Nature biotechnology 3 (1985), S. 1025-1025 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Federal Biotechnology Funding Sources. By Oskar R. Zaborsky and Brenda K. Young. Pp 262. ISBN 0-931-283-23-X. $69.95 (Omec Publishing Company, Washington, D.C.: 1984). Administrators of universities and research centers are generally appreciative of grant receivers and particularly so of ...
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  • 92
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    Nature biotechnology 3 (1985), S. 1024-1024 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Broken Code: The Exploitation of DNA. By Marc Lappé. Pp. 368. ISBN 0-87156-835-7. $17.95. (Sierra Club Books, San Francisco: 1985). A midst the spate of books describing the blue-sky promises of the biotechnology industries comes this thoughtful and thought-provoking volume by Marc ...
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    Nature biotechnology 3 (1985), S. 1026-1027 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] ICN Radiochemicals (Irvine, CA) offers its improved RAPID-Ag-STAIN reagent kit featuring faster, more sensitive staining in the detection of proteins and nucleic acids. The stain works in less than an hour and can be used for proteins, RNA, DNA, and “2-d” electrophoresis in 3 easy ...
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  • 94
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    Nature biotechnology 3 (1985), S. 1029-1029 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Tago, Inc. (Burlingame, CA) is offering a new 24-page catalog on immunological reagents and assays, featuring affinity-isolated antibodies conjugated with Texas Red™ or other fluorochromes, or with one of a variety of enzymes. Write in 701 on Reader Service Card Available from PolyScience ...
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  • 95
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    Nature biotechnology 3 (1985), S. 1030-1030 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Dec. 2–3. Medical China 86. Tarrytown, NY. Info: Robert S. First, Inc., 707 Westchester Ave., White Plains, NY 10604 Dec. 4–8. Idiotype Network and Immune Regulation: Potential Uses in Vaccines and in Understanding Human Diseases. San Antonio, TX. Info: Daniel Watanabe, Interface ...
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  • 96
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    Nature biotechnology 3 (1985), S. 1040-1040 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The National Institutes of Health (NIH) has a special interest in the future of the biotechnology industry, since this fledgling enterprise emerged largely as a result of the NIH's decades-long sustained support for basic research in molecular biology and immunology. Estimates of future sales of ...
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    Nature biotechnology 3 (1985), S. 957-957 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Debate. Scholars of the late Middle Ages called it an argument or disputation. Solemn doctors wrapped in velvet, vair, and ermine hurled quotations of authority at one another, thunderbolts of Aquinas or Aristotle, Augustine or Galen. (Bertolt Brecht recreated one of history's most telling ...
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    Nature biotechnology 3 (1985), S. 961-961 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] RARITAN, N.J.—“We believe it will be the first approved therapeutic monoclonal antibody ever,” says Gideon Goldstein, referring to Orthoclone OKT3™. Goldstein is vice president of immunobiology at Ortho Pharmaceutical Corp., Johnson & Johnson's wholly owned subsidiary ...
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  • 99
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    Nature biotechnology 3 (1985), S. 959-959 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Bacteria may be tentatively regarded as biochemical experimenters; owing to their small size and rapid growth, variations must arise very much more frequently than in more differentiated forms of life, and they can in addition afford to occupy more precarious positions in the natural economy than ...
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    Nature biotechnology 3 (1985), S. 963-963 
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Yet another biotech company has formed yet another marketing agreement with another long-established firm. Nothing new, right? Wrong. This time the upstart genetic engineering company will be doing the marketing. Cetus Corp. (Emeryville, CA) recently announced the formation of ...
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