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  • BIOSCIENCES  (417)
  • 1970-1974  (417)
  • 1971  (417)
  • 101
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    Peptide Hormones in Urine (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-04
    Description: Effects of space flight on bone metabolism investigated by analyzing peptide hormones in urine
    Keywords: BIOSCIENCES
    Type: NASA. Manned Spacecraft Center Proc. of the 1970 Manned Spacecraft Center Endocrine Program Conf.; 10 p
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  • 102
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    Hormonal Control of Calcium Metabolism (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-04
    Description: Assays of hormonal control of calcium and bone metabolism
    Keywords: BIOSCIENCES
    Type: NASA. Manned Spacecraft Center Proc. of the 1970 Manned Spacecraft Center Endocrine Program Conf.; 21 p
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  • 103
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    Human Vasoregulation by Renin, Angiotensin, and Aldosterone (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-04
    Description: Human vasoregulation by renin, angiotensin, and aldosterone and human physiological studies using radioimmunoassays
    Keywords: BIOSCIENCES
    Type: NASA. Manned Spacecraft Center Proc. of the 1970 Manned Spacecraft Center Endocrine Program Conf.; 16 p
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  • 104
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    Joint Ames Research Center/manned Spacecraft Center Study: Diurnal Variation in Adrenocortical and Thyroid Function During Prolonged Bedrest (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-04
    Description: Diurnal variation in endocrine and adrenocortical systems during prolonged bed rest
    Keywords: BIOSCIENCES
    Type: Proc. of the 1970 Manned Spacecraft Center Endocrine Program Conf.; 14 p
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  • 105
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    Review of Metabolic and Endocrine Studies on the Gemini 7 Mission (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-04
    Description: Preflight and postflight analysis of effects of Gemini 7 mission on metabolic and endocrine systems
    Keywords: BIOSCIENCES
    Type: NASA. Manned Spacecraft Center Proc. of the 1970 Manned Spacecraft Center Endocrine Program Conf.; 4 p
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  • 106
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    Hematology Results on Gemini and Apollo Missions (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-04
    Description: Hematological program and biochemical data from Gemini and Apollo missions
    Keywords: BIOSCIENCES
    Type: Proc. of the 1970 Manned Spacecraft Center Endocrine Program Conf.; 14 p
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  • 107
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    Red-Cell-Mass and Plasma-Volume Changes Observed in Astronauts on Three Gemini and Three Apollo Missions (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-04
    Description: Red cell mass and plasma volume changes observed in astronauts on Gemini and Apollo missions
    Keywords: BIOSCIENCES
    Type: NASA Manned Spacecraft Center Proc. of the 1970 Manned Spacecraft Center Endocrine Program Conf.; 11 p
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  • 108
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    Preliminary Results of ACTH Radioimmunoassay (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-03
    Description: Radioimmunochemical assay for ACTH levels in human plasma hormones
    Keywords: BIOSCIENCES
    Type: NASA. Manned Spacecraft Center Proc. of the 1970 Manned Spacecraft Center Endocrine Program Conf.; 11 p
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  • 109
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    Angiographic analysis of heart geometry. (1971)
    In:  Other Sources
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    Publication Date: 2011-08-16
    Description: Basic steps in the acquisition and reconstruction of cardiac dimensions obtained from angiocardiograms for spatial reconstruction and analysis are described, and example applications include a reconstruction of the human left ventricle and a study of the motion of the free wall of the right ventricle in a dog. Computer analysis of the spatial motion of implanted tantalum markers is discussed along with corrections for distortion and magnification incurred in the process. Graphics display of three-dimensional ventricle models is examined, and future improvements in angiocardiographic studies are considered.
    Keywords: BIOSCIENCES
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  • 110
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    Thermoregulatory responses of a hibernator to preoptic and environmental temperatures (1971)
    In:  Other Sources
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    Publication Date: 2011-08-16
    Description: Preoptic and environmental temperature effects on hibernator thermoregulatory responses, noting changes in metabolic rates
    Keywords: BIOSCIENCES
    Type: ; 117-120. (
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  • 111
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    Application of Remote Sensing Techniques for Appraising Changes in Wildlife Habitat (1971)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: An attempt was made to investigate the potential of airborne, multispectral, line scanner data acquisition and computer-implemented automatic recognition techniques for providing useful information about waterfowl breeding habitat in North Dakota. The spectral characteristics of the components of a landscape containing waterfowl habitat can be detected with airborne scanners. By analyzing these spectral characteristics it is possible to identify and map the landscape components through analog and digital processing methods. At the present stage of development multispectral remote sensing techniques are not ready for operational application to surveys of migratory bird habitat and other such resources. Further developments are needed to: (1) increase accuracy; (2) decrease retrieval and processing time; and (3) reduce costs.
    Keywords: BIOSCIENCES
    Type: NASA, Washington Intern. Workshop on Earth Resources Surv. Systems, Vol. 2; p 260-288
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  • 112
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    Medically related activities of application team program (1971)
    In:  CASI
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    Publication Date: 2016-06-07
    Description: Application team methodology identifies and specifies problems in technology transfer programs to biomedical areas through direct contact with users of aerospace technology. The availability of reengineering sources increases impact of the program on the medical community and results in broad scale application of some bioinstrumentation systems. Examples are given that include devices adapted to the rehabilitation of neuromuscular disorders, power sources for artificial organs, and automated monitoring and detection equipment in clinical medicine.
    Keywords: BIOSCIENCES
    Type: Appl. of Aerospace Tech. in Biol. and Med.; 53 p
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  • 113
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    Barotrauma (1971)
    In:  Other Sources
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    Publication Date: 2019-01-25
    Description: Barotrauma from aerospace medicine viewpoint, discussing oxygen absorption, barosinusitis, abdominal distention and aerodontalgia
    Keywords: BIOSCIENCES
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  • 114
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    Radiommunoassay of Antidiuretic Hormone (1971)
    In:  CASI
    Details
    Publication Date: 2014-09-03
    Description: Development of radioimmunoassay system for measurement of urinary antidiuretic hormone excretion
    Keywords: BIOSCIENCES
    Type: NASA Manned Spacecraft Center Endocrine Program Conf.; 19 p
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  • 115
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    The Effect of Temperature on the Survival of Microorganisms in a Deep Space Vacuum (1971)
    In:  Other Sources
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    Publication Date: 2015-08-22
    Description: A space molecular sink research facility (Molsink) was used to evaluate the ability of microorganisms to survive the vacuum of outer space. This facility could be programmed to simulate flight spacecraft vacuum environments at pressures in the .1 nanotorr range and thermal gradients (30 to 60 C) closely associated to surface temperatures of inflight spacecraft. Initial populations of Staphylococcus epidermidis and a Micrococcus sp. were reduced approximately 1 log while exposed to -105 and 34 C, and approximately 2 logs while exposed to 59 C for 14 days in the vacuum environment. Spores of Bacillus subtilis var. niger were less affected by the environment. Initial spore populations were reduced 0.2, 0.3, and 0.8 log during the 14-day vacuum exposure at -124, 34, and 59 C, respectively.
    Keywords: BIOSCIENCES
    Type: Space Life Sciences; 3; Dec. 197
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  • 116
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    Relative Frequency Distribution of D Sub 125 C Values for Spore Isolates from the Mariner Mars 1969 Spacecraft (1971)
    In:  Other Sources
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    Publication Date: 2015-08-22
    Description: Bacterial spore distribution and dry heat resistance on Mariner-Mars 1969 spacecraft, using randomly selected aerobic mesophilic isolates
    Keywords: BIOSCIENCES
    Type: ; YAL SOCIETY (
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  • 117
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    The effects of chronic acceleration of animals - A commentary (1971)
    In:  Other Sources
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    Publication Date: 2019-01-25
    Description: Chronic acceleration effects on animals, considering growth rate, food intake, oxygen metabolism and life expectancy
    Keywords: BIOSCIENCES
    Type: IN- GRAVITY AND THE ORGANISM.; P. 389-411.
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  • 118
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    The state of water in muscle tissue as determined by proton nuclear magnetic resonance. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Keywords: BIOSCIENCES
    Type: Biophysical Journal; 11; Dec. 197
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  • 119
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    Cardiocirculatory responses to exercise - Physiologic study by noninvasive techniques. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: The changes from rest to exercise were determined for certain phases of the cardiac cycle in ten healthy male subjects who underwent submaximal, physiologically paced bicycle ergometry. ECGs, phonocardiograms, and carotid pu lse tracings were recorded. The preejection period and isovolumic contraction time decreased with exercise. Changes in left ventricular ejection time appeared to depend on the severity or the duration of stress. Pulse transmission time did not change significantly. The data obtained in the study and comparison of these results to those obtained by invasive methods indicate that noninvasive techniques, when used in the manner suggested, are appropriate means for detecting a variety of cardiocirculatory changes during exercise.
    Keywords: BIOSCIENCES
    Type: American Heart Journal; 82; Nov. 197
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  • 120
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    Prolongation of RBC survival in the hypophysectomized rat. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Red blood cell (RBC) survival was prolonged in hypophysectomized rats. While the rate of random hemolysis was decreased in some hypophysectomized hosts, in all directly injected and cross-transfused hypophysectomized rat hosts, there was a significant prolongation of the phase of senescent death. In contrast, RBCs from hypophysectomized donors survived normally in normal hosts. These experiments are further evidence of a relationship between RBC aging and metabolic rate, and suggest an intimate involvement with the calorigenic hormones.
    Keywords: BIOSCIENCES
    Type: Society for Experimental Biology and Medicine; vol. 138
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  • 121
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    Chimpanzee sleep stages. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: The electroencephalogram and electro-oculogram of two unrestrained juvenile chimpanzees was monitored for 7 consecutive nights using telemetry methods. Of the sleeping time, 23% was spent in the rapid eye movement of REM type of sleep, whereas 8, 4, 15, and 10% were spent in non-REM stages 1 through 4, respectively. Seven to nine periods of REM sleep occurred per night. The average time from the beginning of one REM period to the beginning of the next was approximately 85 min.
    Keywords: BIOSCIENCES
    Type: Electroencephalography and Clinical Neurophysiology; 31; Nov. 197
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  • 122
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    A study of phycophysiology in controlled environments (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: The primary objective of this research is to obtain fundamental data concerning the growth and metabolism of the unicellular green algae. These organisms are most likely to provide biological oxygen and a food source for space crews. Biochemical conversions, chemical composition, and cell growth and division are discussed. Chlorella sorokiniana is emphasized.
    Keywords: BIOSCIENCES
    Type: NASA-CR-128296 , SASR-22 , TR-1022
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  • 123
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    Environmental microbiology as related to planetary quarantine (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: The results of studies to determine the effect of soil particle size on the survival time at 125 C of the microflora associated with these particles are discussed. The data suggest that longer survival times exist for the microflora associated with larger particles. The studies indicate that microorganisms associated with soil are difficult to kill and that organisms associated with large particles are harder to kill than those associated with small particles. Sterlization requirements increase as the level of contamination increases. Soil particles and their accompanying microflora are the most critical contaminants.
    Keywords: BIOSCIENCES
    Type: NASA-CR-127633 , SAPR-7
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  • 124
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    Altered susceptibility to motion sickness as a function of subgravity level (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: Large interindividual differences among 74 normal subjects in the change in susceptibility to motion sickness with effective lifting of the normal g-load by parabolic flight maneuvers were recorded with high test-retest reliability. Most subjects, who were required to make standardized head movements while seated in a chair rotating at a constant speed, demonstrated either a substantial increase or a decrease in susceptibility, in confirmation of a previous study, while a few appeared to be more or less unaffected by the 1 g to 0 g gravitational change. A similar test procedure conducted with eighteen of the subjects at lunar- and Martian-gravity levels revealed further interindividual differences in susceptiblity as a function of g-level. The subjects with gravity-dependent susceptibility revealed: (1) a progressive change in susceptibility as a function of g-load in either the positive or negative direction that was characteristic of the individual, (2) a susceptibility level that appeared to be maintained at the fractional g-load, and (3) immunity to motion sickness at all g-levels tested below the earth standard. The case history as well as ground-based functional and provocative tests of normal subjects proved to be inadequate in predicting susceptibility to motion sickness under subgravity conditions.
    Keywords: BIOSCIENCES
    Type: NASA-CR-127687 , NAMRL-1150
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  • 125
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    Remote sensing of changes in morphology and physiology of trees under stress (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: Measurements on foliage samples collected from several drought and salt treated plants revealed that leaf thickness decreased with increasing severity of the drought treatment and increased with increasing severity of treatment with NaCl, but remained essentially unaffected by treatment with CaCl2. Airborne data collected by multispectral scanner indicated that false color images provide selective enhancement of a diseased area. Comparison of simulated and actual aerial color and color IR photography revealed that the color renditions of the MSS simulations agreed closely with those of the actual photography.
    Keywords: BIOSCIENCES
    Type: NASA-CR-127640 , APR-5
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  • 126
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    Analytical prediction of the heat transfer from a blood vessel near the skin surface when cooled by a symmetrical cooling strip (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: An analytical method was developed to estimate the amount of heat extracted from an artery running close to the skin surface which is cooled in a symmetrical fashion by a cooling strip. The results indicate that the optimum width of a cooling strip is approximately three times the depth to the centerline of the artery. The heat extracted from an artery with such a strip is about 0.9 w/m-C which is too small to affect significantly the temperature of the blood flow through a main blood vessel, such as the carotid artery. The method is applicable to veins as well.
    Keywords: BIOSCIENCES
    Type: NASA-CR-127460 , ME-TR-344
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  • 127
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    Effect of 90-day continuous exposure to methylisobutylketone on dogs, monkeys and rats (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: Continuous exposure of rats, dogs and monkeys to 410 mg/cu M methylisobutylketone vapor (MIBK) was conducted to evaluate the provisional spacecraft exposure limit of 20 ppm established by the Space Science Board in 1968. The exposure, conducted in a simulated space cabin environment, did not produce any measurable changes in dogs or monkeys. Rats developed hyaline droplet nephrosis within 2 weeks of exposure which was reversible upon removal from the MIBK even after 90 days. The data obtained indicated that the 60-minute emergency exposure limit of 100 ppm and the 90- and 1000-day provisional limits as established by the Space Science Board contain a wide margin of safety.
    Keywords: BIOSCIENCES
    Type: NASA-CR-126744 , W-71003 , AMRL-TR-71-65
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  • 128
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    Metabolic effects of artificial environments (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: The mechanisms by which inert gases influence metabolism were investigated from several viewpoints. Groups of rats were exposed at the thermal neutral temperature of the respective mixtures, to normoxic (P sub A 02 = 100 mm Hq) environments with argon, helium or nitrogen as the diluent at a total pressure of one atmosphere. The possible influence of diluent gases on oxygen transport to the cell was examined with hypoxic (P sub A O2 = 70 mm Hg) mixtures of the same diluent gases. Metabolic measurements included food, water, and oxygen consumption, CO2 production, hematocrit and the rate C-14O2 of expiration subsequent to intraperitoneal injection of acetate-1-C-14 or glucose UL-C-14. Argon-exposed animals showed a consistently decreased metabolic rate while, on the other hand, helium-exposed rats did not significantly alter metabolic rate relative to nitrogen. Certain indices, including acetate and glucose utilization, suggested that helium attenuated the imposed hypoxia at the cellular level while argon facilitated it as compared with nitrogen. These results suggest that metabolic influence of helium is largely thermal in nature while argon has a significant direct metabolic effect and that diluent gases may selectively influence oxygen availability to the interior of the cell.
    Keywords: BIOSCIENCES
    Type: NASA-CR-62079
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  • 129
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    The production and characterization of specific antibodies to aldosterone. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Keywords: BIOSCIENCES
    Type: Immunochemistry; 8; 1971
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  • 130
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    Language and speech capacity of the right hemisphere. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Keywords: BIOSCIENCES
    Type: Neuropsychologia; 9; 1971
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  • 131
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    Renin in differential diagnosis of hypertension. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Renin is a proteolytic enzyme secreted by the kidney. Techniques for the direct measurement of renin content of human blood are not available at the present time. Two of the best known causes of remediable hypertension can be diagnosed from abnormalities in renin activity and aldosterone production. In renovascular hypertension, renin secretion is increased because of impaired glomerular perfusion. The renin activity assay, when applied in a carefully controlled fashion, is a useful screening test for treatable causes of hypertension.
    Keywords: BIOSCIENCES
    Type: American Heart Journal; 82; Oct. 197
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  • 132
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    CPPB and vasopressin secretion. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Discussion of the role of vasopressin (or 'antidiuretic hormone') secretory control system in the maintenance of central vascular volume, and critical comments about the latest paper by Barratz et al. (1971) on the interrelation of antidiuretic hormone (ADH) and fluid balance during continuous positive pressure breathing (CPPB) in dogs. It is felt that, while the increase in plasma ADH levels occurring with CPPB has been more carefully defined in this last paper than previously, still more accurate definitions could be obtained under experimental conditions modified in accordance with presented suggestions.
    Keywords: BIOSCIENCES
    Type: Anesthesiology; 34; June 197
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  • 133
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    A model describing vestibular detection of body sway motion. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: An experimental technique was developed which facilitated the formulation of a quantitative model describing vestibular detection of body sway motion in a postural response mode. All cues, except vestibular ones, which gave a subject an indication that he was beginning to sway, were eliminated using a specially designed two-degree-of-freedom platform; body sway was then induced and resulting compensatory responses at the ankle joints measured. Hybrid simulation compared the experimental results with models of the semicircular canals and utricular otolith receptors. Dynamic characteristics of the resulting canal model compared closely with characteristics of models which describe eye movement and subjective responses to body rotational motions. The average threshold level, in the postural response mode, however, was considerably lower. Analysis indicated that the otoliths probably play no role in the initial detection of body sway motion.
    Keywords: BIOSCIENCES
    Type: Acta Oto-Laryngologica; 72; 1971
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  • 134
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    Airway structure and alveolar emptying in the lungs of sea lions and dogs. (1971)
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    Publication Date: 2019-06-27
    Description: Investigation of the effects of various cycles of compression and decompression on the alveolar volumes of the excised lungs of sea lions and dogs. The results obtained include the finding that, in comparison to dog lungs, sea lion lungs empty more completely on mild compression and much more completely on severe compression. These findings support Scholander's (1940) hypothesis that some marine mammals are protected from decompression sickness by cartilaginous reinforcement of the small airways which permits alveolar emptying during a dive, so isolating compressed gas from pulmonary capillary blood.
    Keywords: BIOSCIENCES
    Type: Respiration Physiology; 13; Dec. 197
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  • 135
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    Study of the Effects of Ultrasonic Waves on the Reproductive Integrity of Mammalian Cells Cultured in Vitro (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: The effects of monochromatic ultrasonic waves of 0.1, 0.5, 1.0, 2.0 and, 3.3 MHz frequency on the colony-forming ability of mammalian cells (M3-1,V79, Chang's and T-1) cultured in vitro have been studied to determine the nature of the action of ultrasonic energy on biological systems at the cellular level. The combined effect of ultrasound and X-rays has also been studied. It is concluded: (1) Ultrasonic irradiation causes both lethal and sublethal damage. (2) There is a threshold dose rate for lethal effects. (3) The effectiveness of ultrasonic waves in causing cell death probably depends on the frequency and the amplitude of the waves for a given cell line, indicating a possible resonance phenomenon.
    Keywords: BIOSCIENCES
    Type: NASA-CR-128356 , LBL-37
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  • 136
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    Steady state and transient temperature distributions in the human thigh covered with a cooling pad (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: An analytical and experimental study was done on the performance of cooling pads attached to a human thigh. Each cooling pad consisted of a long, water cooled tube formed into a serpentine shape with uniform spacing between the parallel sections. The analytical work developed a cylindrical model for the human thigh. The transient times predicted by this model ranged from 25 to 80 minutes, which is reasonably close to the experimental results. Calculated and measured steady state temperature profiles were in fair agreement. The transient times associated with a change from a high metabolic rate of 1800 Btu/hr (528 w) to a low level of 300 Btu/hr (88 w), were found to be about 120 minutes. A change from 300 Btu/hr (264 w) to 300 Btu/hr (88 w) resulted in 90 to 100 minute transients. However, the transient times for a change in metabolic rate in the opposite direction from 300 Btu/hr (88 w) to 1800 Btu/hr (528 w) were 40 to 60 minutes.
    Keywords: BIOSCIENCES
    Type: NASA-CR-127523 , ME-TR-286
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  • 137
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    The effects of spacecraft environments on some hydrolytic enzyme patterns in bacteria (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: The effects of space flight on the production and characteristics of proteolytic enzymes are studied for a number of bacterial species isolated from crew members and spacecraft. Enzymatic make-up and cultural characteristics of bacteria isolated from spacecraft crew members are determined. The organism Aeromonas proteolytica and the proteolytic enzymes which it produces are used as models for future spacecraft experiments.
    Keywords: BIOSCIENCES
    Type: NASA-CR-125805
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  • 138
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    The long winter model of Martian biology - A speculation. (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: A temporal microenvironment model is proposed for Martian biology that is based on an estimated mean thickness of nearly 1 km of frost in the Martian north polar cap summer remnant. If vaporized, this frost could yield not only 1 kg per sq cm of atmosphere, but also higher global temperatures through the greenhouse effect and a greatly increased likelihood of liquid water. Vaporization of such cap remnants may occur twice each equinoctial precession, and Martian organisms may now be in cryptobiotic repose awaiting the end of the long precessional winter. The Viking biology experiments might test this hypothesis.
    Keywords: BIOSCIENCES
    Type: Icarus; 15; Dec. 197
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  • 139
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    Embryogenesis in 100% O2 at reduced pressure. (1971)
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    Publication Date: 2019-06-27
    Description: Fertile chicken eggs were incubated in an altitude chamber in a near 100% O2 atmosphere at 225 torr. Both N2 and CO2 were kept under 0.5%. Temperature was a standard 37.5 C but a high relative humidity of 90% was required to prevent dehydration. In ten trials involving 382 eggs, hatchability averaged 21% of controls and weight of chicks was 11% less than controls, but embryo mortality was distributed similarly. Low pressure per se and small differences in O2 tension may have affected the results, but similarities to incubation in 21% O2-79% He call attention to absence of nitrogen as a possible explanation.
    Keywords: BIOSCIENCES
    Type: Space Life Sciences; 3; Dec. 197
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  • 140
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    The role of perilymph in the response of the semicircular canals to angular acceleration. (1971)
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    Publication Date: 2019-06-27
    Description: A new model for the response of the semicircular canals to angular motion is postulated. This model is based on evidence that the bony canal is not compartmentalized and assumes that the ampulla wall is highly flexible. It is shown that the perilymph induces a cupula displacement far greater than that produced by the endolymph alone. The predicted dynamic behavior of the canals on the basis of this model is found to be consistent with experimental observations.
    Keywords: BIOSCIENCES
    Type: Acta Otolaryngologica; 72; 1971
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  • 141
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    Circulatory responses to hypoxia in experimental myocardial infarction. (1971)
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    Publication Date: 2019-06-27
    Description: Three levels of decreased arterial oxygen saturation elicited a graded circulatory response in dogs, manifested by stepwise increases in cardiac output, left ventricular dp/dt, and stroke volume, and decreases in systemic vascular resistance. Responses to similar hypoxia challenges after experimental myocardial infarction were qualitatively similar but quantitatively less. Although the circulatory compensation for hypoxia was less effective after myocardial infarction, no further deterioration of the haemodynamics was noted.
    Keywords: BIOSCIENCES
    Type: Cardiovascular Research; 5; Oct. 197
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  • 142
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    Origin and development of plasma membrane derived invaginations in Vinca rosea l. (1971)
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    Publication Date: 2019-06-27
    Description: The occurrence, morphology, and possible ontogeny of plasma-membrane-related structures are described which can develop into invaginations or intravacuolar formations. An underlying study of meristematic tissues from the shoot of Vinca rosea supports the interpretation that endocytosis does occur in plant cells and that it is appropriate to refer to these structures as endocytoses. The function of these invaginations or their content remains to be elucidated.
    Keywords: BIOSCIENCES
    Type: American Journal of Botany; 58; 5, 19; 1971
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  • 143
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    Hypothalamic stimulation and baroceptor reflex interaction on renal nerve activity. (1971)
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    Publication Date: 2019-06-27
    Description: The basal level of mean renal nerve activity (MRNA-0) measured in anesthetized cats was found to be modified by the additive interaction of hypothalamic and baroceptor reflex influences. Data were collected with the four major baroceptor nerves either intact or cut, and with mean aortic pressure (MAP) either clamped with a reservoir or raised with l-epinephrine. With intact baroceptor nerves, MRNA stayed essentially constant at level MRNA-0 for MAP below an initial pressure P1, and fell approximately linearly to zero as MAP was raised to P2. Cutting the baroceptor nerves kept MRNA at MRNA-0 (assumed to represent basal central neural output) independent of MAP. The addition of hypothalamic stimulation produced nearly constant increments in MRNA for all pressure levels up to P2, with complete inhibition at some level above P2. The increments in MRNA depended on frequency and location of the stimulus. A piecewise linear model describes MRNA as a linear combination of hypothalamic, basal central neural, and baroceptor reflex activity.
    Keywords: BIOSCIENCES
    Type: American Journal of Physiology; 221; Dec. 197
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  • 144
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    Erythropoietic radiosensitivity of the rat during altitude acclimatization. (1971)
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    Publication Date: 2019-06-27
    Description: The effect of a sublethal dose (300 R) of X-radiation upon the erythropoietic system of the rat, during 60-day acclimatization to moderate hypoxia (3,800 m altitude), was studied. Past work has shown that hypoxic animals are damaged less by radiation than animals irradiated in a normal environment; therefore, it was postulated that if, after acclimatization to hypoxia the bone marrow oxygen tension returns to sea-level values, these animals should suffer radiation damage equivalent to animals at sea level. The principal parameters followed were the rate of depletion of injected Fe-59 from the plasma of chronically catheterized rats, and its subsequent reappearance in the circulating erythrocytes. After 20 days of acclimatization, both parameters for altitude-irradiated animals returned to the values of animals irradiated at sea level, previously having reflected increased erythropoiesis. In altitude nonirradiated animals the parameters indicated erythropoietic stimulation persisting up to 45 days acclimatization. The protective effect of the hypoxia on the stem cells vanished during acclimatization, presumably as cellular oxygen tension rose.
    Keywords: BIOSCIENCES
    Type: American Journal of Physiology; 221; Dec. 197
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  • 145
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    Myocardial correlates of helium-cold induction and maintenance of hypothermia. (1971)
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    Publication Date: 2019-06-27
    Description: Hypothermia was induced in the golden hamster Mesocricetus auratus, using the helium-cold method. The first group of hamsters was sacrificed immediately after induction to rectal temperature 7 C, a second group was sacrificed after being maintained at a body temperature of 7 C for 18-24 hr, and a third group consisted of unexposed controls. The hearts were excised and the ventricles analyzed for hypoxic damage, glycogen, and catecholamines. In the short-term hypothermic animals, resting tension was increased while peak isometric tension, generated tension after 10 min of anoxic exposure, glycogen, and catecholamines were all reduced. All of the functional parameters recovered in the long-term hypothermic group, while glycogen and catecholamines showed a trend toward recovery. It is concluded that myocardial hypoxia develops during induction into hypothermia when using the helium-cold method. This effect is reversible and hypoxic damage does not increase as the hypothermic exposure is prolonged.
    Keywords: BIOSCIENCES
    Type: American Journal of Physiology; 221; Dec. 197
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  • 146
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    Temperature adaptation of active sodium-potassium transport and of passive permeability in erythrocytes of ground squirrels. (1971)
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    Publication Date: 2019-06-27
    Description: Unidirectional active and passive fluxes of K-42 and Na-24 were measured in red blood cells of ground squirrels (hibernators) and guinea pigs (nonhibernators). As the temperature was lowered, ?active' (ouabain-sensitive) K influx and Na efflux were more considerably diminished in guinea pig cells than in those of ground squirrels. The fraction of total K influx which is ouabain-sensitive in red blood cells of ground squirrels was virtually constant at all temperatures, whereas it decreased abruptly in guinea pig cells as temperature was lowered.
    Keywords: BIOSCIENCES
    Type: Journal of General Physiology; 58; Dec. 197
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  • 147
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    Mechanism of pulmonary conversion of angiotensin I to angiotensin II in the dog. (1971)
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    Publication Date: 2019-06-27
    Description: The conversion mechanism was studied in vivo in the pulmonary circulation of the intact anesthetized dog and in vitro in plasma by using L-Leu-angiotensin I, D-Leu-angiotensin I, and des-Leu-angiotensin I which had been synthesized by the solid-phase technique. The results obtained indicate that pulmonary conversion in vivo and plasma conversion in vitro occur via a dipeptidylcarboxypeptidase and that a D-amino acid at the C-terminus prevents conversion.
    Keywords: BIOSCIENCES
    Type: Circulation Research; 29; Dec. 197
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  • 148
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    Dry-heat Resistance of Bacillus Subtilis Var. Niger Spores on Mated Surfaces (1971)
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    Publication Date: 2019-06-27
    Description: Bacillus subtilis var. niger spores were placed on the surfaces of test coupons manufactured from typical spacecraft materials including stainless steel, magnesium, titanium, and aluminum. These coupons were then juxtaposed at the inoculated surfaces and subjected to test pressures of 0, 1000, 5000, and 10,000 psi. Tests were conducted in ambient, nitrogen, and helium atmospheres. While under the test pressure condition, the spores were exposed to 125 C for intervals of 5, 10, 20, 50, or 80 min. Survivor data were subjected to a linear regression analysis that calculated decimal reduction times.
    Keywords: BIOSCIENCES
    Type: Applied Microbiology; 22; Oct. 197
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  • 149
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    Parathyroid hormone - Secretion and metabolism in vivo. (1971)
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    Publication Date: 2019-06-27
    Description: Gel filtration and radioimmunoassay were used to determine the molecular size and immunochemical reactivity of parathyroid hormone present in gland extracts, in the general peripheral circulation, and in parathyroid effluent blood from patients with hyperparathyroidism, as well as from calves and from cattle. It was found that parathyroid hormone secreted from the parathyroids in man and cattle is at least as large as the molecule extracted from normal bovine glands. However, once secreted into the circulation the hormone is cleaved, and one or more fragments, immunologically, dissimilar to the originally secreted hormone, constitute the dominant form of circulating immunoreactive hormone.
    Keywords: BIOSCIENCES
    Type: National Academy of Sciences; vol. 68
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  • 150
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    Effect of circadian rhythm on CNS oxygen toxicity. (1971)
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    Publication Date: 2019-06-27
    Description: The circadian rhythm in susceptibility to oxygen toxicity seizures was investigated by using six groups of 20 male Sprague-Dawley rats (101-196 gm.). The animals were given standard chow, exposed to standard diurnal conditions of light (0700-1900 hr) and dark (1900-0700 hr), and fasted for 15-16 hr prior to exposure to hyperbaric oxygen. The animals were placed in a previously oxygen flushed chamber and raised to 60 psi (gauge) oxygen at a rate of 3 psi/min. Time of exposure started with attainment of 60 psi. End point was first convulsion. The animals' weights were equally distributed within the groups, and the groups were defined by hour of exposure. Time of exposure in minutes prior to seizure was significantly longer in those exposed at 0700-0800 hr and 1000-1100 hr than in four other groups. There was no relationship between animals' weights and time of exposure to seizures. All R values were negative, and the highest R value was -035. These data suggest a definite circadian rhythm in susceptibility to oxygen toxicity seizures.
    Keywords: BIOSCIENCES
    Type: Aerospace Medicine; 42; Dec. 197
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  • 151
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    Effect of altered 'weight' upon animal tolerance to restraint. (1971)
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    Publication Date: 2019-06-27
    Description: The effect of altered weight upon animal tolerance to restraint was determined by simulating various accelerative forces with directed lead weights using restrained and nonrestrained domestic fowl (chickens). Weighting (increased weight) and conterweighting (reduced weight) produced a stressed condition - reduced relative lymphocyte counts, loss of body mass, and/or the development of a disorientation syndrome - in both restrained and nonrestrained (caged only) birds. The animal's tolerance to altered weight appeared to be a function of its body weight. Unrestrained birds were stressed by counterweighting (mean plus or minus standard error) 58.3 plus or minus 41% of their body weight, whereas restrained birds tolerated only 32.2 plus or minus 2.6% reduction in body weight. A training regimen for restrained birds was not effective in improving their tolerance to a reduced weight environment. It was concluded that domestic fowl living in a weightless (space) environment should be restrained minimally and supported by ventrally directed tension equivalent to approximately 50% of their body mass (their weight in a 1 G environment).
    Keywords: BIOSCIENCES
    Type: Aerospace Medicine; 42; Dec. 197
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  • 152
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    Further studies on the dimensionless parameters associated with the 'in vivo' transport of heat within biological tissue. (1971)
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    Publication Date: 2019-06-27
    Description: Dimensionless parameters appearing in the analysis of transport of heat within living biological tissues are presented and discussed. Dimensional analysis as well as some analytical solutions have been employed to obtain the physically and physiologically most significant dimensionless parameters associated with these types of problems. Some analytical solutions are presented for both steady state and transient cases to illustrate the significance of the derived parameters.-
    Keywords: BIOSCIENCES
    Type: Aerospace Medicine; 42; Dec. 197
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  • 153
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    Brain serotonin content - Increase following ingestion of carbohydrate diet. (1971)
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    Publication Date: 2019-06-27
    Description: In the rat, the injection of insulin or the consumption of carbohydrate causes sequential increases in the concentrations of tryptophan in the plasma and the brain and of serotonin in the brain. Serotonin-containing neurons may thus participate in systems whereby the rat brain integrates information about the metabolic state in its relation to control of homeostasis and behavior.
    Keywords: BIOSCIENCES
    Type: Science; 174; Dec. 3
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  • 154
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    Physiological control - A physical view: Life and the biochemical oscillator. (1971)
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    Publication Date: 2019-06-27
    Description: The history and progress of physical interpretations of physiological control, viewing life as a biochemical oscillator, are surveyed. Special attention is given to the author's studies (1964, 1965, 1968 and 1969) and to studies of Katchalsky (1969) who demonstrated a 1,000-A scale which may provide a basis for a biochemical oscillator.
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  • 155
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    Continuous propagation of microalgae. III. (1971)
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    Publication Date: 2019-06-27
    Description: Data are presented which give the specific photosynthetic rate and the specific utilization rates of urea and carbon dioxide as functions of specific growth rate for Chlorella. A mathematical model expresses a set of mass balance relations between biotic and environmental materials. Criteria of validity are used to test this model. Predictive procedures are complemented by a particular model of microbial growth. Methods are demonstrated for predicting substrate utilization rates, production rates of extracellular metabolites, growth limiting conditions, and photosynthetic quotients from propagator variables.
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  • 156
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    Effect of gravitoinertial force on ocular counterrolling. (1971)
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    Publication Date: 2019-06-27
    Description: The effect of G loading on the magnitude of ocular counterrolling at various angles of tilt up to 63 deg. was measured on normal subjects and compared with the effect on persons with severe or complete loss of vestibular function. The group of six normal subjects manifested a compensatory eye roll which increased as a direct and essentially linear function of the component of the gravitoinertial force acting laterally on the subject. This increase in response was not observed in the five deaf subjects with severe or complete bilateral loss of their vestibular organs. These findings confirmed similar results found by other authors using other measuring techniques which show that the reflex eye movement is dependent on and limited to the magnitude of the gravitoinertial stimulus (within the range used) when the otolithocular system is functioning normally. However when this function is severely impaired or lost, the magnitude of the compensatory eye roll is limited to that manifested at 1 G and possibly to nonotolithic contributions. These findings offer means for differentiation between otolithic-defective and ?normal' persons who exhibit little counterrolling.
    Keywords: BIOSCIENCES
    Type: Journal of Applied Physiology; 31; Nov. 197
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  • 157
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    Comparisons of the polypeptide chains of globins. (1971)
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    Publication Date: 2019-06-27
    Description: Discussion of the amino acid differences and minimum base differences per codon due to mutations which took place during divergent evolution of vertebrates from a common ancestral gene. The ?random mutation model' of evolution is examined by comparing a carp alpha Hb chain and six mammalian alpha Hb chains in terms of the genetic code. The occurrence of recognizable three-base changes is analyzed and a summary of the distribution of changes in the hemoglobin and myoglobin chains is given for 148 sites.
    Keywords: BIOSCIENCES
    Type: Journal of Molecular Evolution; 1; 1, 19; 1971
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  • 158
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    Role of cardiac output and the autonomic nervous system in the antinatriuretic response to acute constriction of the thoracic superior vena cava. (1971)
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    Publication Date: 2019-06-27
    Description: Study of the differential characteristics of hepatic congestion and decreased cardiac output in terms of potential afferent stimuli in the antinatriuretic effect of acute thoracic inferior vena cava (TIVC) constriction. An attempt is made to see if the autonomic nervous system is involved in the antinatriuretic effect of acute TIVC or thoracic superior vena cava constriction.
    Keywords: BIOSCIENCES
    Type: Circulation Research; 29; Nov. 197
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  • 159
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    Factors involved in the antinatriuretic effects of acute constriction of the thoracic and abdominal inferior vena cava. (1971)
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    Publication Date: 2019-06-27
    Description: Study of the antinatriuretic effect of acute thoracic inferior vena cava (TIVC) constriction in the absence of alterations in renal perfusion pressure. A comparison is made of the effects of equivalent degrees of TIVC and abdominal inferior vena cava constriction on arterial pressure, renal hemodynamics, and electrolyte excretion.
    Keywords: BIOSCIENCES
    Type: Circulation Research; 29; Nov. 197
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  • 160
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    Peripheral venous scintillation angiocardiography in determination of left ventricular volume in man. (1971)
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    Publication Date: 2019-06-27
    Description: Left ventricular end-diastolic volume was determined by cardiac visualization after peripheral venous injection of a gamma-emitting isotope in 10 patients with organic heart disease. The left ventricular end-diastolic volume measured by the isotope method consistently averaged 9% less than that determined by the X-ray method. The mean difference in left ventricular end-diastolic volume was 21 ml. Excellent correlation between the two methods was observed. It is pointed out that peripheral venous scintillation angiocardiography compares well with left ventriculography in the determination of left ventricular end-diastolic volume in man.
    Keywords: BIOSCIENCES
    Type: American Journal of Cardiology; 28; Nov. 197
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  • 161
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    Inhaled ozone as a mutagen. II - Effect on the frequency of chromosome aberrations observed in irradiated Chinese hamsters. (1971)
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    Publication Date: 2019-06-27
    Description: Exposure-adjusted break frequencies for chromosome aberrations produced in Chinese hamster circulating blood lymphocytes were the quantitative indicator of damage from 5 hrs of exposure to X-radiation and/or to ozone. Radiation produced 5.51 x 0.0001 breaks/cell rad for cells withdrawn 2 weeks after exposure, a reasonable value when compared with data from in vivo exposure of human lymphocytes and Chinese hamster bone marrow cells. Animals exposed to the two agents simultaneously exhibited more than 70% of the total breaks anticipated assuming the expected equal contributions to be additive. Extending to humans, at presently permitted levels, exposure to ozone would be much more detrimental than exposure to radiati*n.
    Keywords: BIOSCIENCES
    Type: Environmental Research; 4; Oct. 197
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  • 162
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    Some observations on the three-dimensional growth of L5178Y cell colonies in soft agar culture. (1971)
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    Publication Date: 2019-06-27
    Description: The three-dimensional organization of spherical colonies formed by L5178Y cells grown in soft agar cultures was investigated by light and scanning electron microscopy. Visible colonies were formed after 7 days of incubation and increased in size for more than 2 weeks. At this time the colonies contained a central core of necrotic cells surrounded by an outer shell of normal-looking cells in loose contact with each other. Cross sectional radioautographs revealed that tritiated precursors were incorporated only into those cells in the ?viable cell' shell and not in the necrotic center of the colony. It is pointed out that increased knowledge of the factors leading to this type of three-dimensional organization is of particular interest, since it is similar to the conditions found in certain types of solid tumors (Thomlinson and Gray, 1955).
    Keywords: BIOSCIENCES
    Type: Experimental Cell Research; 65; 1971
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  • 163
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    Effect of varying ventricular function by extrasystolic potentiation on closure of the mitral valve. (1971)
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    Publication Date: 2019-06-27
    Description: Mitral regurgitant indexes were measured by roentgen videodensitometry in anesthetized dogs without thoracotomy before, during and after extrasystolic potentiation of ventricular contraction while the atria and ventricles were driven in normal temporal sequence simultaneously or in such a way as to induce atrial fibrillation. Small amounts of mitral reflux were observed with simultaneous atrial and ventricular driving and with atrial fibrillation in the control measurements before initiation of extrasystolic potentiation. Reflux became negligible during extrasystolic potentiation and increased beyond control levels after termination of extrasystolic potentiation.
    Keywords: BIOSCIENCES
    Type: American Journal of Cardiology; 28; July 197
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  • 164
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    Fluid dynamics in flexible tubes: An application to the study of the pulmonary circulation (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: Based on an analysis of unsteady, viscous flow through distensible tubes, a lumped-parameter model for the dynamics of blood flow through the pulmonary vascular bed was developed. The model is nonlinear, incorporating the variation of flow resistance with transmural pressure. Solved using a hybrid computer, the model yields information concerning the time-dependent behavior of blood pressures, flow rates, and volumes in each important class of vessels in each lobe of each lung in terms of the important physical and environmental parameters. Simulations of twenty abnormal or pathological situations of interest in environmental physiology and clinical medicine were performed. The model predictions agree well with physiological data.
    Keywords: BIOSCIENCES
    Type: NASA-CR-127111
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  • 165
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    Biochronometry; Proceedings of the Symposium, Friday Harbor, Wash., September 4-6, 1969. (1971)
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    Publication Date: 2019-07-27
    Description: Topics discussed include circadian activity rhythms in birds and man, variation of circadian rhythms in monkeys, resetting of circadian eclosion rhythm in fruitflies, the effectiveness of mathematical models of circadian rhythms, the influence of ac electric fields on circadian rhythms in man, the relation between changes in the metabolic rate and circadian periodicity of the resistance of pocket mice to ionizing radiation, the relation between circadian organization and the photoperiodic time measurement in moths, the circadian rhythm of optic nerve potentials in the isolated eye of the sea hare, phasing of circadian temperature rhythms in the pocket mouse by specific spectral regions, the phase-shifting effect of light on circadian rhymicity in the fruifly, hormonal control of circadian rhythms in the fruitfly, metabolically controlled temperature compensation in the circadian rhythm of algae, and circadian rhythms in the chloroplasts of algae. Individual items are abstracted in this issue.
    Keywords: BIOSCIENCES
    Type: Biochronometry; Symposium; Sept. 4-6, 1969; Friday Harbor, WA
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  • 166
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    Environmental microbiology as related to planetary quarantine (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: The experiments carried out to determine the effects of temperature and relative humidity on the survival rate of Bacillus subtillis var. niger spores are reported. The experiments were conducted in environmental chambers at temperatures of 75 and 90 C. Data are also included on the survival characteristics of the spores suspended in sucrose solutions at 90 C with water activities of 0.99, 0.9, and 0.85
    Keywords: BIOSCIENCES
    Type: NASA-CR-123326 , SAPR-6
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  • 167
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    Radiation hazards to man (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: The secondary dose contribution expected from the heavy primaries of the galactic cosmic rays was evaluated by a calculational technique developed in this study. Improvements in the solar and galactic cosmic ray environments made possible by recent experimental and theoretical work are discussed and presented. The recommendations of the National Academy of Sciences' space radiation study panel, are used in conjunction with a shielding analysis, to evaluate the radiation status of an astronaut during the triple solar particle event of 10, 14, 16 July 1959.
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    Type: NASA-CR-125592 , D180-12878-1
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  • 168
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    GLC analysis of base composition of RNA and DNA hydrolysates (1971)
    In:  CASI
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    Publication Date: 2019-06-27
    Description: Various methods used for the analysis of the base composition of RNA and DNA hydrolysates are presented. The methods discussed are: (1) ion-exchange chromatography, (2) paper chromatography, (3) paper electrophoresis, (4) thin layer chromatography, (5) paper chromatography and time of flight mass spectrometry, and (6) gas-liquid chromatography. The equipment required and the conditions for obtaining the best results with each method are described.
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    Type: NASA-CR-125593
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  • 169
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    Rapid delayed luminescence from chloroplasts kinetic analysis of components - The relationship to the O2 evolving system (1971)
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    Publication Date: 2019-06-27
    Description: Saturating flash delayed luminescence from chloroplasts, considering relationship to oxygen evolution
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    Type: ; PORTS OF STATISTICAL
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  • 170
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    Potassium chloride-insoluble myofilaments in vertebrate smooth muscle cells (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Nonactomyosin component differentiation in potassium chloride insoluble myofilaments in vertebrate smooth muscle cells
    Keywords: BIOSCIENCES
    Type: ; VIGATION (
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  • 171
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    Origin of organic matter in early solar system. IV - Amino acids- Confirmation of catalytic synthesis by mass spectrometry (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Prebiotic organic matter in solar system, investigating contamination free amino acid catalytic synthesis from deuterated reactants
    Keywords: BIOSCIENCES
    Type: ; 331-335. (
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  • 172
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    Origin of organic matter in early solar system. III - Amino acids- Catalytic synthesis (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Early solar system organic matter origin, discussing amino acid synthesis from CO, H and ammonia reaction with N, alumina or clay catalysts
    Keywords: BIOSCIENCES
    Type: ; 331-335. (
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  • 173
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    Unknown
    Observing behavior in squirrel monkeys under a multiple schedule of reinforcement availability (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Observing behavior in squirrel monkeys under multiple schedule of reinforcement availability
    Keywords: BIOSCIENCES
    Type: ; 331-335. (
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  • 174
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    Unknown
    Urease reaction rates at low water activity (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Urea hydrolysis reaction rates by urease at low water activity, noting use for Mars surface bioassay
    Keywords: BIOSCIENCES
    Type: ; 104-111. (
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  • 175
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    Behavioral responses to linear accelerations in blind goldfish. I - The gravity reference response (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Blind goldfish gravity reference response under linear accelerations on motor car and parallel swing from movie camera recording
    Keywords: BIOSCIENCES
    Type: ; 104-111. (
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  • 176
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    Unknown
    An electrostatic computer model of a biological membrane (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Computerized electrostatic field model of biological cell membrane
    Keywords: BIOSCIENCES
    Type: ; 104-111. (
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  • 177
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    Mechanism of antidiuretic action of chlorpropamide in the mammalian kidney (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Antidiuretic action of chlorpropamide in mammalian kidney, considering intrarenal infusions effect on urinary concentration, free water clearance, glomerular filtration and sodium excretion
    Keywords: BIOSCIENCES
    Type: ; 104-111. (
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  • 178
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    Unknown
    Diurnal patterns in water and food intake and body weight changes in rats with hypothalamic lesions (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Diurnal water and food intake and body weight changes pattern in rats with hypothalamic lesions
    Keywords: BIOSCIENCES
    Type: ; 104-111. (
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  • 179
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    Stimulation experience and incentive variables as determinants of behavior elicited by hypothalamic stimulation (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Incentive goal and extensive stimulation experience effects on proportion increase of hypothalamic electrode sites yielding elicited eating and drinking behavior
    Keywords: BIOSCIENCES
    Type: ; TROPHYSICAL JOURNAL
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  • 180
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    Unknown
    Vascular and extravascular fluid changes during six days of bedrest (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Human vascular and extravascular fluid changes during six days bedrest based on fluid volume and ideal body weight from individual heights
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 181
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    Bone density changes in a Macaca nemestrina monkey during the Biosatellite III project (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Macaca nemestrina monkey bone density change during Biosatellite 3 mission
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 182
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    Unknown
    Bicarbonate requirement for elimination of the lag period of Hydrogenomonas eutropha (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Bicarbonate requirement for elimination of lag period of chemoautrophically grown Hydrogenomonas eutropha
    Keywords: BIOSCIENCES
    Type: ; ADEMIE DES SCIENCES
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  • 183
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    Unknown
    Chronic acceleration of animals (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Animals physiological responses to gravity chronic acceleration
    Keywords: BIOSCIENCES
    Type: IN- GRAVITY AND THE ORGANISM.; P. 371-378, 388.
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  • 184
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    Unknown
    Central nervous responses to gravitational stimuli (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Central nervous tissue sensitivity, considering direct sensing of gravitational stimuli of vibratory character
    Keywords: BIOSCIENCES
    Type: IN- GRAVITY AND THE ORGANISM.; P. 293-310.
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  • 185
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    Effects of long-term shock and associated stimuli on aggressive and manual responses (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Long term exposure to electric shock and associated stimuli on squirrel monkeys, considering aggressive and manual responses
    Keywords: BIOSCIENCES
    Type: ; 269-345. (
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  • 186
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    Unknown
    Transmission of small pressure waves in the canine vena cava (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Small pressure wave transmission in abdominal venae cavae of dogs in mathematical model development for viscoelastic behavior of large veins
    Keywords: BIOSCIENCES
    Type: ; ANSPORTURI AUTO, NAV
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  • 187
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    Unknown
    Water intake and urine output of mice during chronic centrifugation (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Chronic centrifugation effects on water intake and urine output in mice, considering food intake and growth rate
    Keywords: BIOSCIENCES
    Type: ; ANSPORTURI AUTO, NAV
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  • 188
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    L-dopa - Disaggregation of brain polysomes and elevation of brain tryptophan (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Brain polysomes disaggregation and tryptophan elevation in immature rats and adult animals after L-dopa administration
    Keywords: BIOSCIENCES
    Type: ; ANSPORTURI AUTO, NAV
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  • 189
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    Unknown
    Action of pharmacologic agents in experimental cardiac tamponade (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Isoproterenol, atrial pacing, ouabain and methoxamine effects on dogs during experimental cardiac tamponade, observing arterial pressure, cardiac output and heart rate changes
    Keywords: BIOSCIENCES
    Type: ; ANSPORTURI AUTO, NAV
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  • 190
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    Unknown
    In vivo and in vitro determinations of body fat and body water in the hamster (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Hamster body fat, water and density measurements by dilution method and air displacement technique, comparing to determination by direct chemical analysis upon sacrificing
    Keywords: BIOSCIENCES
    Type: ; DIOTEKHNIKA (
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  • 191
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    Extraretinal correction and memory for target position (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Extraretinal correction and memory for target position, suggesting corrective tendency of eye movements in dark
    Keywords: BIOSCIENCES
    Type: ; 251-289. (
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  • 192
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    Simulation of passive thermal behavior of a cooling biological system - Entry into hibernation (1971)
    In:  Other Sources
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    Publication Date: 2019-06-27
    Description: Thermal behavior simulation of cooling biological system, describing heat generation and transfer at normothermic to hibernating body temperatures with mathematical model
    Keywords: BIOSCIENCES
    Type: ; YAL SOCIETY (
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  • 193
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    Sea urchin egg fertilization and development (1971)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: The effects of subgravity (much less than unit gravity) on fertilization, cell division, differentiation, and growth of a relatively simple biological system (eggs of the sea urchin Arbacia punctulata) were considered. The experiment was flown on Gemini 3 and recovered as scheduled. However, the experiment objectives were not achieved, primarily for mechanical reasons.
    Keywords: BIOSCIENCES
    Type: EXPT-S002 , The Gemini Program Biomed. Sci. Expt. Sum.; p 245-247
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  • 194
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    Human otolith function, experiment M009 (1971)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: The experiments that were performed during the Gemini 5 and 7 missions resulted in quantitative information concerning otolithic function and orientation of four subjects exposed to an orbiting spacecraft environment for prolonged periods of time. Preflight counterrolling measurements revealed significant differences between crewmembers with regard to the basic magnitude of otolith response. However, after the flight, each crewmember maintained his respective preflight level of response. This was indicative that no significant change in otolithic sensitivity occurred as a result of the flight, or at least no change persisted long enough to be recorded several hours after recovery. The EVLH data recorded for each subject confirmed the observation that a coordinate space sense exists even in a weightless environment if contact cues are adequate. However, it was noted that the apparent location of the horizontal within the spacecraft may not agree necessarily with its physical correlate in the spacecraft.
    Keywords: BIOSCIENCES
    Type: EXPT-M009 , NASA. Manned Spacecraft Center The Gemini Program Biomed. Sci. Expt. Sum.; p 155-170
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  • 195
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    Calcium and nitrogen balance, experiment M007 (1971)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: The collection of data on the response of the skeletal and muscular systems to 14-day space flights was evaluated for loss of calcium, nitrogen, and other metabolically related elements. Considerable interindividual variability was demonstrated in all experimental factors that were measured. Calcium balance became less positive and urinary phosphate excretion increased substantially in flight despite a reduction in phosphate intake. Patterns of excretion of magnesium, sodium, potassium, and chloride were different for each subject, and, in part, could be correlated with changes in adrenocortical steroid production. The principal hormonal change was a striking decrease during flight in the urinary excretion of 17-hydroxycortocosteroids. Dermal losses of calcium, magnesium, sulfate, and phosphate were insignificant during all three phases.
    Keywords: BIOSCIENCES
    Type: EXPT-M007 , NASA. Manned Spacecraft Center The Gemini Program Biomed. Sci. Expt. Sum.; p 87-110
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  • 196
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    Applications of aerospace technology in biomedicine. A technology transfer profile: Patient monitoring (1971)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: NASA contributions to cardiovascular monitoring are described along with innovations in intracardiac blood pressure monitoring. A brief overview of the process of NASA technology transfer in patient monitoring is presented and a list of bioinstrumentation tech briefs and the number of requests for technical support is included.
    Keywords: BIOSCIENCES
    Type: NASA-CR-124817
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  • 197
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    The effect of variable calcium and very low calcium diets on human calcium metabolism (1971)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: The effects of a very low calcium diet, with variable high and low protein intake, on the dynamics of calcium metabolism and the mechanism of calciuretics, are examined. The experiment, using male subjects, was designed to study the role of intestinal calcium absorption on urinary calcium excretion, and the rate of production of endogeneously secreted calcium in the gastrointestinal tract. The study showed an average of 70% fractional absorption rate during very low calcium intake, and that a decrease in renal tubular reabsorption of calcium is responsible for calciuretic effects of high protein intake. The study also indicates that there is a tendency to develop osteoporosis after long periods of low calcium intake, especially with a concurrent high protein intake.
    Keywords: BIOSCIENCES
    Type: NASA-CR-115244
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  • 198
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    Experimental system for the control of surgically induced infections (1971)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: The results are presented of the development tests performed on the experimental system for the control of surgically induced infections. Tests were performed on the portable clean room to demonstrate assembly, collapsability, portability and storage. Collapsing, relocating and storing within the surgery room can be accomplished in 12 minutes. The storage envelope dimensions are 1.64 m x 4.24 m x 2.62 m high. The disassembly transfer to another room, and reassembly were demonstrated. The laminar air flow velocity profile within the enclosure was measured. In the undisturbed area of the enclosure the air flow met the Federal Standard 209a requirements of 27.45 meters per minute + or - 6.10 meters per minute. Smoke tests with simulated surgery equipment and personnel in the enclosure did not indicate any detrimental air flow patterns. It is concluded that the system as designed will perform the functions required for its intended use.
    Keywords: BIOSCIENCES
    Type: NASA-CR-124619 , D203613-007 , MCR-71-329
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  • 199
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    Electron tunneling as a basis for semiconduction in proteins (1971)
    In:  CASI
    Details
    Publication Date: 2019-06-27
    Description: Electron tunneling is investigated as a possible mechanism for the conduction of electrical current in solids composed of protein molecules. An intermolecular potential barrier is assumed which takes into account the applied electric field and the possibility of image charge effects. The WKB approximation is used to calculate the net tunneling current density and resulting conductivity. The results suggest that electron tunneling per se is not a suitable mechanism for explaining the observed conductivities in such materials.
    Keywords: BIOSCIENCES
    Type: NASA-TN-D-6559 , E-6483
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  • 200
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    Inhaled ozone as a mutagen. I - Chromosome aberrations induced in Chinese hamster lymphocytes (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: Lymphocyte chromosome aberrations by inhaled ozone in Chinese hamster, indicating mutagen damage
    Keywords: BIOSCIENCES
    Type: ; PORTS OF STATISTICAL
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