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  • Books  (1,859)
  • Cham :Springer International Publishing :  (1,741)
  • Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación
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  • 1
    Online Resource
    Online Resource
    Translational Neuroscience of Speech and Language Disorders (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. Translational Neuroscience of Speech and Language Disorders: State of the Art. -2. Translational Neuroscience of Aphasia and Adult Language Rehabilitation. -3. Treatment and intervention approaches for the improvement of language abilities in neurodegenerative diseases -- 4. Neural and Genetic Mechanisms of Dyslexia -- 5. The role of memory systems in neurodevelopmental disorders of language -- 6. Transcranial direct current stimulation (tDCS) and Language/Speech: Can patients benefit from a combined therapeutic approach? -- 7. Transcranial Magnetic Stimulation in Aphasia Rehabilitation -- 8. The Cerebellum: A Therapeutic Target in Treating Speech and Language Disorders -- 9. Navigated rTMS for Mapping the Language Network in Preoperative Settings: Current Status and Future Prospects -- 10. Presurgical Language fMRI in Epilepsy: An Introduction -- 11. Lesion-symptom mapping in speech and language disorders: a translational perspective.
    Abstract: This edited volume provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative conditions on speech and language. It brings together contributions from several leading experts in a markedly broad range of disciplines, including Speech and Language Therapy, Neuropsychology and Neurology, but also Neurosurgery, Neuroimaging and Neurostimulation, as well as Engineering and Genetics.
    Type of Medium: Online Resource
    Pages: XVII, 290 p. 18 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030356873
    Series Statement: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-030-35687-3
    DOI: 10.1007/978-3-030-35687-3
    DDC: 612.8
    Language: English
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  • 2
    Online Resource
    Online Resource
    Beyond Our Genes : Pathophysiology of Gene and Environment Interaction and Epigenetic Inheritance (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medical genetics. ; Genetics. ; Biotechnology. ; Medical Genetics. ; Genetics and Genomics. ; Chemical Bioengineering.
    Description / Table of Contents: Section I: The physiology of the gene/environment interaction -- Nutrition -- Physical Exercise -- Circadian Rhythm -- Toxicants: Smoke, Alcohol and Heavy Metals -- Hormones -- Section II: Gene-Environment Interaction and Disease Susceptibility -- Obesity and Metabolic Syndromes -- Cancer -- Neurological and Psychiatric Disorders -- Asthma and allergic disorders -- Lamarck Versus Darwin: The Concept of Aquired Epigenetic Inheritance -- Section III: Genome/Epigenome -- Genetic Contribution to Epigenetic Inheritance -- The Controversial Role of DNA Methylation in Epigenetic Inheritance -- Small Non-Coding RNAs -- Chromatin Modifiers -- Soma-to-Germline Information Transfer: Questions and Promises.
    Abstract: The genotype/phenotype dichotomy is being slowly replaced by a more complex relationship whereby the majority of phenotypes arise from interactions between one’s genotype and the environment in which one lives. Interestingly, it seems that not only our lives, but also our ancestors’ lives, determine how we look. This newly recognized form of inheritance is known as (epi)genetic, as it involves an additional layer of information on top of the one encoded by the genes. Its discovery has constituted one of the biggest paradigm shifts in biology in recent years. Understanding epigenetic factors may help explain the pathogenesis of several complex human diseases (such as diabetes, obesity and cancer) and provide alternative paths for disease prevention, management and therapy. This book introduces the reader to the importance of the environment for our own health and the health of our descendants, sheds light on the current knowledge on epigenetic inheritance and opens a window to future developments in the field.
    Type of Medium: Online Resource
    Pages: VIII, 266 p. 11 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030352134
    URL: https://doi.org/10.1007/978-3-030-35213-4
    DOI: 10.1007/978-3-030-35213-4
    DDC: 616.042
    Language: English
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  • 3
    Online Resource
    Online Resource
    Conservation Genetics in Mammals : Integrative Research Using Novel Approaches (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Conservation biology. ; Ecology . ; Molecular ecology. ; Animal migration. ; Animal culture. ; Biodiversity. ; Biotic communities. ; Population biology. ; Conservation Biology. ; Molecular Ecology. ; Animal Migration. ; Animal Science. ; Biodiversity. ; Community and Population Ecology.
    Description / Table of Contents: (1) Introduction on different applications of molecular tools to answer novel questions in the field of population genetics/genomics of endangered mammals (Mike Bruford, School of Biosciences, Cardiff University, UK) -- (2) Climate change impact at the genetic level: patterns in the Couesi's rice rat Oryzomys couesi (Ella Vázquez Domínguez, Instituto de Ecología, UNAM, Mexico) -- (3) Use of molecular and demographic data to prioritize populations of black-tailed prairie dogs (Cynomys ludovicianus) from Chihuahua, Mexico for conservation (Luis Eguiarte Fruns, Instituto de Ecología, UNAM, Mexico) -- (4) Anthropogenic and Historic Movements of American Black Bears Shape Contemporary Population Structure (Emily Puckett, Division of Molecular Sciences, University of Missouri, USA) -- (5) How many ESUs are of conservation interest within some species of Neotropical carnivores (Felidae, Canidae, Ursidae, Mustelidae and Procyonidae)? : Individual mitocondrial genes versus mitogenomics (Manuel Ruiz García, Departamento de Biología, Pontificia Universidad Javeriana, Spain) -- (6) Phylogeographic footprint of armadillo colonization in North America (María Clara Arteaga, Departamento de Biología de la Conservación, Mexico) -- (7) Koala conservation in Queensland: a role for a living genome bank in genetic rescue? (Jenny Seddon, School of Veterinary Science, The University of Queensland, Australia) -- (8) Noninvasive genetics sheds light on the status, phylogeography, and evolution of the most elusive carnivores: The case of the snow leopard (Jan Janecka, Department of Biological Sciences, Duquesne University, USA) -- (9) Documenting genetic diversity in changing populations for management and conservation (Jennifer Leonard, Conservation and Evolutionary Genetics, Estación Biológica de Doñana, Spain) -- (10) Conservation genetic of gray brocket deer (Mazama gouazoubira) in the southern of the distribution range (Susana González, Departamento de Biodiversidad y Genética, Universidad de Uruguay) -- (11) Noninvasive Genetic Monitoring of the Elusive European Wildcat as a Tool for Science-Based Wildlife Conservation (Katharina Steyer, Seckenberg Research Institute, Germany) -- (12) Conservation genetics in bats: current progress and future prospects (Serena Dool, University of Greifswald, Germany) -- (13) From dung to demography: Using noninvasive methods to study elephants inside and outside protected areas (Lori Eggert, Division of Biological Sciences, University of Missouri, USA) -- (14) Effect of the habitat connectivity in the genetic variability of the Volcano rabbit (Romerolagus diazi) (Jorge Ortega/Leslie Montes/José Antonio Guerrero, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional) -- (15) Different immune system diversity for city life: comparing major histocompatiblity complex alleles in San Joaquin kit fox (Vulpes macrotis mutica) (Jesus Maldonado/Tammy R Wilbert, Masoumeh Sikaroodi, Brian Cypher, Christine Van Horn Job, Katherine Ralls, and Patrick M. Gillevet, Center for Conservation Genomics, Smithsonian Institue, Washington, DC, USA) -- (16) Conclusion: current state and future prospects of conservation genomics in mammals (Jorge Ortega, Jesus Maldonado).
    Abstract: This book focuses on the use of molecular tools to study small populations of rare and endangered mammals, and presents case studies that apply an evolutionary framework to address innovative questions in the emerging field of mammalian conservation genomics using a highly diverse set of novel molecular tools. Novel and more precise molecular technologies now allow experts in the field of mammology to interpret data in a more contextual and empirical fashion and to better describe the evolutionary and ecological processes that are responsible for the patterns they observe. The book also demonstrates how recent advances in genetic/genomic technologies have been applied to assess the impact of environmental/anthropogenic changes on the health of small populations of mammals. It examines a range of issues in the field of mammalian conservation genomics, such as the role that the genetic diversity of the immune system plays in disease protection and local adaptation; the use of noninvasive techniques and genomic banks as a resource for monitoring and restoring populations; the structuring of population by physical barriers; and genetic diversity. Further, by integrating research from a variety of areas – including population genetics, molecular ecology, systematics, and evolutionary and conservation biology – it enables readers to gain a deeper understanding of the conservation biology of mammals that are at increasing risk of extinction at local, regional and global scales. As such, it offers a unique resource for a broad readership interested in the conservation biology of mammals and conservation management strategies to better preserve biodiversity.
    Type of Medium: Online Resource
    Pages: VII, 378 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030333348
    URL: https://doi.org/10.1007/978-3-030-33334-8
    DOI: 10.1007/978-3-030-33334-8
    DDC: 333.9516
    Language: English
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  • 4
    Online Resource
    Online Resource
    Notch Signaling in Embryology and Cancer : Molecular Biology of Notch Signaling (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Embryology. ; Cancer Biology. ; Cell Biology. ; Embryology.
    Description / Table of Contents: Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling -- Overview of Basic Mechanisms of Notch Signaling in Development and Disease -- Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate -- Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling -- Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster -- Molecular Regulation of Notch Signaling by Gremlin -- Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex -- Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss -- Insulin–dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation -- Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
    Type of Medium: Online Resource
    Pages: XIII, 172 p. 32 illus., 31 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030364229
    Series Statement: Advances in Experimental Medicine and Biology, 1227
    URL: https://doi.org/10.1007/978-3-030-36422-9
    DOI: 10.1007/978-3-030-36422-9
    DDC: 571.978
    Language: English
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  • 5
    Online Resource
    Online Resource
    Natural Materials and Products from Insects: Chemistry and Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Invertebrates. ; Biotechnology. ; Biomaterials. ; Invertebrate Zoology. ; Biotechnology. ; Biomaterials.
    Description / Table of Contents: 1. Polyphenols and flavonoids from honey: Biological applications -- 2. Chemistry and application of lac and its by-products -- 3. Silk: an amazing biomaterial for future medication -- 4. Insect Chitin and Chitosan: Structure, Properties, Production and Implementation Prospective -- 5. Recent advances in the arthropod natural product chemistry -- 6. Silkworm: A Unique Creature for Natural Products -- 7. Present and future prospects on nutritious feeding using insects -- 8. Insect Pheromones and its applications in management of pest population -- 9. Non-Protein chemical compounds from Lepidopteran insect cocoons. .
    Abstract: This book reviews the latest research on bioproducts from various economically important insects, such as silkworms, honey bees, lac and drosophila, and termites, and discusses their general, biomedical and industrial applications in detail. It includes chapters focusing on insects as a food source, probiotics, silk-based biomaterials, insect pheromones, insects as biomedicine source, pupa oil chemistry, non-protein compounds from Lepidopteran insects, insect chitin and chitosan, polyphenols and flavonoids. Model insects like Bombyx mori or bees were domesticated in Asian countries thousands of years ago. Over time, natural products from these animals became industrialized and today they attracting increasing attention thanks to their sustainability and their manifold applications in agriculture and biomedicine. The book is intended for entomologists, material scientists, natural product researchers and biotechnologists. .
    Type of Medium: Online Resource
    Pages: X, 156 p. 44 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030366100
    URL: https://doi.org/10.1007/978-3-030-36610-0
    DOI: 10.1007/978-3-030-36610-0
    DDC: 592
    Language: English
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  • 6
    Online Resource
    Online Resource
    Neurosecretion: Secretory Mechanisms (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurosciences. ; Anatomy. ; Internal medicine. ; Cytology. ; Biochemistry. ; Neuroscience. ; Anatomy. ; Internal Medicine. ; Cell Biology. ; Biochemistry.
    Description / Table of Contents: Neurosecretion: A Historical Overview -- Neurosecretion: Hypothalamic Somata versus Neurohypophysial Terminals -- Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus -- Somato-Dendritic Secretion of Neuropeptides -- Neurosecretory Vesicles: Structure, Distribution, Release and Breakdown -- Molecular Controls on Regulated Neurotransmitter and Neurohormone Secretion -- Secretory Astrocytes -- Action Potential-Induced Ca2+ Influx for Both Acute and Sustained Insulin Secretion in Pancreatic Beta Cells -- Plasticity in the Morphology of Lactotrophs and Folliculo-Stellate Cells and Prolactin Secretion -- Neuroendocrine and Metabolic Regulation of Plasma Growth Hormone Secretory Profiles -- Role of the TWIK-Related Potassium (TREK)-1 Channels in the Regulation of Adrenocorticotropic Hormone (ACTH) Secretion from Pituitary Corticotropes -- How Do Bacterial Neurotoxins Affect Neurosecretion? -- Secretory Mechanisms in Paramecium.
    Abstract: How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley.
    Type of Medium: Online Resource
    Pages: XIII, 307 p. 65 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030229894
    Series Statement: Masterclass in Neuroendocrinology, 8
    URL: https://doi.org/10.1007/978-3-030-22989-4
    DOI: 10.1007/978-3-030-22989-4
    DDC: 612.8
    Language: English
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  • 7
    Online Resource
    Online Resource
    The Pangenome : Diversity, Dynamics and Evolution of Genomes (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbial genetics. ; Evolution (Biology). ; Population genetics. ; Microbial ecology. ; Medical genetics. ; Genetics. ; Microbial Genetics. ; Evolutionary Biology. ; Population Genetics. ; Microbial Ecology. ; Medical Genetics. ; Genetics and Genomics.
    Description / Table of Contents: Part 1: Genomic diversity and the pan-genome concept -- Chapter 1: The pan-genome: a data-drivendiscovery in biology -- Chapter 2: The prokaryotic species concept and challenges -- Chapter 3: Bacterial guide on how to design a diversified gene portfolio -- Chapter 4: A review of pan-genome tools and recent studies -- Part 2: Evolutionary biology of pan-genomes -- Chapter 5: Structure and dynamics of bacterial populations: pan-genome ecology -- Chapter 6: Bacterial microevolution and the pan-genome -- Chapter 7: Pan-genomes and selection: the public goods hypothesis -- Chapter 8: A pan-genomic perspective on the emergence, maintenance and predictability of antibiotic resistance -- Part 3: Pan-genomics: an open, evolving discipline -- Chapter 9: Metapangenome: at the crossroad of pangenomics and metagenomics -- Chapter 10: Pan-genome flux balance analysis towards pan-phenomes -- Chapter 11: Bacterial epigenomics: epigenetics in the age of population genomics -- Chapter 12: Eukaryotic pan-genomes -- Chapter 13: Computational strategies for eukaryotic pan-genome analyses.
    Abstract: This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
    Type of Medium: Online Resource
    Pages: XIV, 307 p. 47 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030382810
    URL: https://doi.org/10.1007/978-3-030-38281-0
    DOI: 10.1007/978-3-030-38281-0
    DDC: 579.135
    Language: English
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  • 8
    Online Resource
    Online Resource
    The Citrus Genome (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Plant genetics. ; Plant biotechnology. ; Agriculture. ; Plant Genetics. ; Plant Biotechnology. ; Agriculture.
    Description / Table of Contents: Citrus origin, diffusion and economic importance -- Genetic resources of Citrus and related genera -- Conventional breeding of cultivated varieties -- Conventional breeding of rootstocks -- Ploidy manipulation as breeding strategy -- Markers, maps and marker-assisted selection -- From the draft genome of sweet orange toward a pan-genome -- New Breeding Techniques for Citrus -- From flower to fruit in citrus -- Genetic control of ripening -- Pigments in citrus: importance and genetic background -- Essential oils in citrus -- Abiotic stress resistance -- Biotechnological approaches for the resistance to citrus huanglongbling -- Genetic basis of canker resistance -- Molecular mechanisms for resistance to biotic stresses -- Future perspectives.
    Abstract: This book reviews how the release of the citrus genome facilitates the investigation of ancestral species, the study of their complex biological features, and the genetic basis of agronomic traits of paramount importance for their sustainable cultivation. The first chapters discuss citrus origin and distribution, and the economic importance and varietal composition of the cultivated species, providing an overview of citrus and related genera genetic resources. The book then describes the role of traditional breeding techniques (for scion and rootstocks) as well as the potential of genomic breeding and innovative protocols for biotechnological approaches. The second part provides essential information on the genus Citrus, the attributes of pure citrus species, genetic admixtures, hybrids and citrus relatives, and on the horticultural classification of cultivated species, varieties and rootstocks. The third part then focuses on the different molecular mechanisms, covering various aspects of citrus biology, including the role of beneficial compounds of citrus fruits. In addition, it examines the molecular responses of citrus to abiotic stresses and to field and post-harvest diseases. Providing insights gained in recent years, it is a valuable guide for those who are interested in gene discovery, comparative genomics, molecular breeding and new breeding techniques. It is particularly useful for scientists, breeders and students at universities and public sector institutes involved in research for the citrus industry.
    Type of Medium: Online Resource
    Pages: XIV, 294 p. 33 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030153083
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-15308-3
    DOI: 10.1007/978-3-030-15308-3
    DDC: 581.35
    Language: English
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  • 9
    Online Resource
    Online Resource
    Combined Discrete and Continual Approaches in Biological Modelling (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Bioinformatics. ; Surfaces (Physics). ; System theory. ; Zoology. ; Botany. ; Biology Technique. ; Computational and Systems Biology. ; Surface and Interface and Thin Film. ; Complex Systems. ; Zoology. ; Plant Science. ; Biological Techniques.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Various methods of pattern formation -- Chapter 3. Clusterization of biological structures with high aspect ratio -- Chapter 4. Contact between biological attachment devices and rough -- Chapter 5. Anisotropic friction in biological systems -- Chapter 6. Mechanical interlocking of biological fasteners -- Chapter 7. Biomechanics at the microscale -- Chapter 8. Nanoscale pattern formation in biological surfaces -- Chapter 9. Ecology and evolution.
    Abstract: Basic laws of nature are rather simple, but observed biological structures and their dynamic behaviors are unbelievably complicated. This book is devoted to a study of this “strange” relationship by applying mathematical modeling to various structures and phenomena in biology, such as surface patterns, bioadhesion, locomotion, predator-prey behavior, seed dispersal, etc. and revealing a kind of self-organization in these phenomena. In spite of diversity of biological systems considered, two main questions are (1) what does self-organization in biology mean mathematically and (2) how one can apply this knowledge to generate new knowledge about behavior of particular biological system? We believe that this kind of “biomimetics” in computer will lead to better understanding of biological phenomena and possibly towards development of technical implications based on our modeling.
    Type of Medium: Online Resource
    Pages: XVIII, 317 p. 151 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030415280
    Series Statement: Biologically-Inspired Systems, 16
    URL: https://doi.org/10.1007/978-3-030-41528-0
    DOI: 10.1007/978-3-030-41528-0
    DDC: 570.285
    Language: English
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  • 10
    Online Resource
    Online Resource
    Sustainable Management of Invasive Pests in Africa (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Invertebrates. ; Invertebrate Zoology.
    Description / Table of Contents: 1. Agriculture and Impact of Invasive Species to Productivity in Africa -- 2. Bioassay-Guided Isolation of Active Phytochemicals Against Tuta Absoluta (Meyrick) from Turraea Floribunda and Caesalpinia Welwitschiana -- 3. Tuta Absoluta (Meyrick): Seasonal Abundance and Susceptibility of some Tomato Genotypes in Gezira State, Sudan -- 4. Evaluation of Resistance and Toxicity of different Insecticides on Tuta absoluta Meyrick Populations in Major Tomato Growing States of Nigeria -- 5. The First Effort at Adopting Integrated Pest Management IPM to Contain the Infestation of the Tuta Absoluta in Nigeria -- 6. New Record of Tuta Absoluta on Cowpea Vigna Unguiculata, Gezira State, Sudan -- 7. Efficacy of a Sudanese Strain of Entomopathogenic Fungus, Metarhizium Anisopliae Met. Sorokin on Puparia of Bactrocera Dorsalis Hendel, under Laboratory Conditions -- 8. Taxonomic keys to Economic Fruit Flies (Diptera: Tephritidae) of the Sudan -- 9. Injury and Yield Losses due to the Maize Stem Borer Busseola Fusca (Fuller) (Lepidoptera: Noctuidae) on Smallholder farms. -- 10. Establishment of an Exotic Parasitoid Cotesia vestalis in Coastal Areas of Kenya as Biological Control Agent of Plutella Xylostella -- 11. Enhancing Monitoring Efficiency and Management of Vectors of Maize Lethal Necrosis Disease in Kenya -- 12. Outbreak of fall Armyworm (Spodoptera Frugiperda) and its Impact in Rwanda Agriculture Production -- 13. Farmers’ Perceptions and Preferences on Pesticide use in the Management of Fall armyworm in Rwanda -- 14. Chronological Review of Fruit Fly Research and Management Practices in Sudan -- 15. Integrated Pest Management for Control the Date Palm Green Pit Scale Insect Palmapsis Phoenicis Ra (Homoptera: Asterolecaniidae) in Sudan -- 16. Use of Para-Pheromone Methyl Eugenol for Suppression of the Mango Fruit Fly, Bactrocera Dorsalis (Hendel) (Diptera:Tephritidae) in Southern Ethiopia -- 17. Sudan Thematic Implementation Plan for the Management of Invasive Red Palm Weevil (RPW), Rhynchophorus Ferrugineus (Olivier) -- 18. Management of Pests of Quarantine Importance in Ghana’s Export Vegetables (Chili, Eggplant and Ridged Gourds) -- 19. The Role of Plantwise in Improving Detection and Action on Pest Situations -- 20. Semiochemical-Baited Autodissemination Device for Managing BFT on Cowpea -- 21. Influence of Predatory Mites, Phytoseiulus Longipes Evans. on the Within-Plant Diurnal Migration and Distribution of the Red Spider Mite, Tetranychus Evansi, Baker and Pritchard on African Nightshade, Solanum Scabrum -- 22. Effects and Persistence of Endophytic Beauveria Bassiana in Tomato Varieties on Mite Density Tetranychus Evansi in the Screenhouse -- 23. Flight Behaviour and Activity Time of Tuta absoluta (Meyrick) Males Trapped on Tomato and Miscellaneous Crops, Gezira State, Sudan.
    Abstract: Invasive species, generally, affect economically important crops, thus affecting the livelihoods of millions of people along crop value chains. Typically, invasive species have high migratory capabilities and, because of plant material exchanges made during trade, they cannot be contained by one country. Usually, African countries react after a pest has invaded and established itself in the country, making the cost of mitigating the pest even more expensive. This book presents a pan-African view of the impacts of invasive insect pests on agriculture and of how invasive species impact on productivity in Africa. It not only describes their importance, but also presents a diversity of research findings in the field, ranging from the use of early warning and monitoring systems for quarantine purposes, agricultural extension, all the way to control strategies. The IPM arsenal presented in this book includes the use of botanical bioactive compounds, semiochemicals, resistant varieties, biological control agents such as entomopathogens, endophytes, predators, and natural enemies. Aspects of technology transfer strategies, regional coordination, and farmers’ perceptions have not been overlooked, because these affect the adoption of mitigation strategies. The book also presents measures that would help agricultural research services to estimate the damage and take actions for preparedness and readiness to face invasive insect pests. This starts with a basic knowledge of taxonomy to enable concerned persons to describe the insects and the vast inventory of affected crops. Physiological and ecological aspects of invasive pests are strongly highlighted to strengthen Integrated Pest Management Strategies. The threat of invasive species will remain permanent; therefore, the book encourages knowledge exchange and collaboration between researchers and scientists on the continent, while encouraging the establishment of a platform or a fund for preparedness and rapid response.
    Type of Medium: Online Resource
    Pages: XXVI, 303 p. 64 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030410834
    Series Statement: Sustainability in Plant and Crop Protection, 14
    URL: https://doi.org/10.1007/978-3-030-41083-4
    DOI: 10.1007/978-3-030-41083-4
    DDC: 592
    Language: English
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  • 11
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    Online Resource
    Astrobiology and Cuatro Ciénegas Basin as an Analog of Early Earth (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Evolution (Biology). ; Astrobiology. ; Planetary science. ; Evolutionary Biology. ; Astrobiology. ; Planetary Science.
    Description / Table of Contents: Preface -- Chapter 1. What is astrobiology? -- Chapter 2. Astrobiology and Planetary Sciences in Mexico -- Chapter 3. Was LUCA a Hyperthermophilic Prokaryote? The Impact-Bottleneck Hypothesis Revisited -- Chapter 4. Stromatolites, Biosignatures, and Astrobiological Implications -- Chapter 5. The global distribution of modern microbialites: not so uncommon after all -- Chapter 6. The importance of the rare biosphere for astrobiological studies and the diversification and resilience of life on Earth -- Chapter 7. Bacterial communities from deep-hydrothermal systems: the southern Gulf of California as an example of primeval environments -- Chapter 8. Andean Microbial Ecosystems: traces in hypersaline lakes about life origin -- Chapter 9. Stromatolites in crater-lake Alchichica and Bacalar lagoon -- Chapter 10. The origin and early evolution of life on Earth: A laboratory in the School of Science -- Chapter 11. Cuatro Ciénegas as an Archaean Astrobiology Park -- Index.
    Abstract: Astrobiology not only investigates how early life took hold of our planet but also life on other planets – both in our Solar System and beyond – and their potential for habitability. The book take readers from the scars on planetary surfaces made by space rocks to the history of the Solar System narrated by those space rocks as well as exoplanets in other planetary systems. But the true question is how life arose here or elsewhere. Modern comparative genomics has revealed that Darwin was correct; a set of highly conserved genes and cellular functions indicate that all life is related by common ancestry. The Last Universal Common Ancestor or LUCA sits at the base of the Tree of Life. However, once that life took hold, it started to diversify and form complex microbial communities that are known as microbial mats and stromatolites. Due to their long evolutionary history and abundance on modern Earth, research on the biological, chemical and geological processes of stromatolite formation has provided important insights into the field of astrobiology. Many of these microbialite-containing ecosystems have been used as models for astrobiology, and NASA mission analogs including Shark Bay, Pavilion and Kelly Lakes. Modern microbialites represent natural laboratories to study primordial ecosystems and provide proxies for how life could evolve on other planets. However, few viral metagenomic studies (i.e., viromes) have been conducted in microbialites, which are not only an important part of the community but also mirror its biodiversity. This book focuses on particularly interesting sites such as Andean lake microbialites, a proxy of early life since they are characterized by very high UV light, while Alchichica and Bacalar lakes are characterized by high-salt and oligotrophic waters that nurture stromatolites. However, it is only the oasis of Cuatro Ciénegas Basin in México that stored past life in its marine sediments of the Sierra de San Marcos. This particular Sierra has a magmatic pouch that moves the deep aquifer to the surface in a cycle of sun drenched life and back to the depths of the magmatic life in an ancient cycle that now is broken by the overexploitation of the surface water as well as the deep aquifer in order to irrigate alfalfa in the desert. The anthropocene, the era of human folly, is killing this unique time machine and with it the memory of the planet.
    Type of Medium: Online Resource
    Pages: VIII, 232 p. 41 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030460877
    Series Statement: Cuatro Ciénegas Basin: An Endangered Hyperdiverse Oasis,
    URL: https://doi.org/10.1007/978-3-030-46087-7
    DOI: 10.1007/978-3-030-46087-7
    DDC: 576.8
    Language: English
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  • 12
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    Nanopesticides : From Research and Development to Mechanisms of Action and Sustainable Use in Agriculture (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Agriculture. ; Microtechnology. ; Microelectromechanical systems. ; Environmental chemistry. ; Nanochemistry. ; Environmental policy. ; Agriculture. ; Microsystems and MEMS. ; Environmental Chemistry. ; Nanochemistry. ; Environmental Policy.
    Description / Table of Contents: Chapter 1 - State of the art of the development of nanopesticides and their potential benefits -- Chapter 2 - Understanding the interaction of nanopesticides with plants -- Chapter 3 - Study of the interaction of nanopesticides with soil microbiota -- Chapter 4 - Methods for understanding the interaction of nanopesticides with soil and water -- Chapter 5 - State of the art in ecotoxicological assays to study the effects of nanopesticides against non-target organisms -- Chapter 6 - Nanoherbicides -- Chapter 7 - Nanoinsecticides -- Chapter 8 - Nanofungicides -- Chapter 9 - Alternative models for initial screening of nanopesticides safety -- Chapter 10 - Methods for the evaluation toxicological effects of nanopesticides in humans -- Chapter 11 - Use of DNA/RNA and nanotechnology aiming pest control -- Chapter 12 - Regulatory issues regarding Nanopesticides Chapter 13 - Nanopesticides: from the bench to the market -- Chapter 14 - Nanopesticides: risk analysis.
    Abstract: This book explores the development of nanopesticides and tests of their biological activity against target organisms. It also covers the effects of nanopesticides in the aquatic and terrestrial environments, along with related subjects including fate, behaviour, mechanisms of action and toxicity. Moreover, the book discusses the potential risks of nanopesticides for non-target organisms, as well as regulatory issues and future perspectives.
    Type of Medium: Online Resource
    Pages: XXI, 360 p. 56 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030448738
    URL: https://doi.org/10.1007/978-3-030-44873-8
    DOI: 10.1007/978-3-030-44873-8
    DDC: 630
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  • 13
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    Online Resource
    Pediatric Pharmacotherapy (2020)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    URL: https://doi.org/10.1007/978-3-030-50494-6
    DOI: 10.1007/978-3-030-50494-6
    DDC: 615
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  • 14
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    Online Resource
    DNA Barcoding and Molecular Phylogeny (2020)
    Cham :Springer International Publishing :
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    Keywords: Evolution (Biology). ; Plant genetics. ; Genetics. ; Microbial genetics. ; Evolutionary Theory. ; Plant Genetics. ; Genetics and Genomics. ; Microbial Genetics.
    Abstract: This book presents a comprehensive overview of DNA barcoding and molecular phylogeny, along with a number of case studies. It discusses a number of areas where DNA barcoding can be applied, such as clinical microbiology, especially in relation to infection management; DNA database management; and plant -animal interactions, and also presents valuable information on the DNA barcoding and molecular phylogeny of microbes, algae, elasmobranchs, fishes, birds and ruminant mammals. Furthermore it features unique case studies describing DNA barcoding of reptiles dwelling in Saudi Arabian deserts, genetic variation studies in both wild and hatchery populations of Anabas testudineus, DNA barcoding and molecular phylogeny of Ichthyoplankton and juvenile fishes of Kuantan River in Malaysia, and barcoding and molecular phylogenetic analysis of indigenous bacteria from fishes dwelling in a tropical tidal river. Moreover, since prompt identification and management of invasive species is vital to prevent economic and ecological loss, the book includes a chapter on DNA barcoding of invasive species. Given its scope, this book will appeal not only to researchers, teachers and students around the globe, but also to general readers.
    Type of Medium: Online Resource
    Pages: VI, 267 p. 41 illus., 23 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030500757
    URL: https://doi.org/10.1007/978-3-030-50075-7
    DOI: 10.1007/978-3-030-50075-7
    DDC: 576.801
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  • 15
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    Online Resource
    Medicinal and Aromatic Plants of North America (2020)
    Cham :Springer International Publishing :
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    Keywords: Botany. ; Agriculture. ; Plant physiology. ; Plant Science. ; Agriculture. ; Plant Physiology.
    Description / Table of Contents: Chapter 1. Introduction to MAPs in the North America -- Chapter 2. Dr. Duke's Phytochemical and Ethnobotanical databases, a cornerstone in the validation of ethnoveterinary medicinal plants, as demonstrated by data on pets in British Columbia -- Chapter 3. Pharmacopoeial Wild Medicinal Plants of North America -- Chapter 4. Medicinal Plant Products, a Discussion of Actual or Probable versus Perceived Sources -- Chapter 5. Juniper species in North America to the same species in Europe with respect to phytochemistry and bioactivity -- Chapter 6. Mentha Genetic Diversity at the US National Clonal Germplasm Repository in Corvallis, Oregon -- Chapter 7. Advances in the research of basil -- Chapter 8. Advances in ther research of catnip -- Chapter 9. Diversity, conservation and sustainable harvest of medicinal plants in North America -- Chapter 10. The Great botanist, Jim Duke -- Chapter 11. TBC -- Chapter 12. Taxol or the story of the American yew -- Chapter 13. The Indian Tobacco -- Chapter 14. The American Elderberry -- Chapter 15. The American Ginseng.
    Abstract: This volume is aimed at offering an insight into the present knowledge of the vast domain of Medicinal and Aromatic Plants with a focus on North America. In this era of global climate change the volume is meant to provide an important contribution to a better understanding of the diverse world of Medicinal and Aromatic Plant research, production and utilization.
    Type of Medium: Online Resource
    Pages: VIII, 342 p. 59 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030449308
    Series Statement: Medicinal and Aromatic Plants of the World, 6
    URL: https://doi.org/10.1007/978-3-030-44930-8
    DOI: 10.1007/978-3-030-44930-8
    DDC: 580
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  • 16
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    Online Resource
    Integrative Biological Control : Ecostacking for Enhanced Ecosystem Services (2020)
    Cham :Springer International Publishing :
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    Keywords: Invertebrates. ; Applied ecology. ; Biodiversity. ; Microbial ecology. ; Conservation biology. ; Ecology . ; Forestry. ; Invertebrate Zoology. ; Applied Ecology. ; Biodiversity. ; Microbial Ecology. ; Conservation Biology. ; Forestry.
    Description / Table of Contents: 1. Preface -- 2. Improving the efficacy of biological control by ecostacking -- 3. Integrative biological control approaches in Chinese agriculture, Biodiversity enhancement for improving biological control -- 4. Perennial wildflower strips to enhance natural enemies of insect pests in Belgium -- 5. Flower strips for ecosytem services in Switzerland, Felix Herzog, Agroscope, Zurich Switzerland -- 6. Enhancement of natural control functioning of rice insect pests by manipulating biodiversity in rice-based ecosystems -- 7. Cover crops enhance biological control of insect pests in apple orchards in China -- 8. Enhancement of natural control function in aphids by intercropping and infochemical releasers in wheat ecosystem -- 9. Crop diversity and disease control,Specific techniques to enhance ecostacking -- 10. Ecological enhancement of arthropod natural enemy application in biological control -- 11. Chemical ecology of egg parasitoids in crop protection -- 12. Current knowledge on the migratory moth Autographa gamma as basis for future chemo-ecological research -- 13. The development of biocontrol products and their applications in the field -- 14. Effects of insecticides on pollen beetles (Brassicogethes aeneus) and their tersilochine parasitoids in Germany -- 15. How microbiome approaches can assist market development for biological control -- 16. Successful use of entomopathogenic nematodes to control a defoliator outbreak in an environmentally sensitive area -- 17. Bees and medicinal plants -- 18. Climate change implications -- 19. Night warming on predator-prey interactions: implications for biological control -- 20. Landscape-level drivers of biocontrol and case study from local to regional scale under climate change in China -- 21. Spotted Wing Drosophila-blueberry interactions.
    Abstract: This book is the first to integrate biological control into a conceptual framework – ecostacking - uniting all aspects of biological control and ecosystem services. In 2018 the "First International Congress of Biological Control" was organised and held in Beijing, China. The chapters highlight some of the achievements presented at the congress, worldwide. Of particular significance are the numerous contributions by Chinese researchers illustrating the remarkable progress made on developing and adopting multiple biological control strategies over vast agricultural areas, largely replacing chemical pesticides for sustainable agricultural and horticultural production. In many parts of the world including Europe, fragmented research based on short-term funding has been unable to answer to the needs to develop sustainable long-term solutions to crop protection, while colleagues in China have been successful in implementing programs that exemplify the power of the ecostacking approach. Key contributions by European and US specialists combined with the expertise and experiences by the Chinese contributors comprise the building blocks for the integration of biological control approaches into the overall frame of ecostacking. This book will lead the way to a broader, integrated adoption of biological control techniques in sustainable pest, disease and weed management supporting also the functioning of other key ecosystem services. Chapter 2 of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 248 p. 63 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030448387
    Series Statement: Progress in Biological Control, 20
    URL: https://doi.org/10.1007/978-3-030-44838-7
    DOI: 10.1007/978-3-030-44838-7
    DDC: 592
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  • 17
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    Surgical Treatment of Epilepsies : Diagnosis, Surgical Strategies, Results (2020)
    Cham :Springer International Publishing :
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    Keywords: Nervous system Surgery. ; Neurology . ; Nervous system Radiography. ; Neuropsychology. ; Neurosurgery. ; Neurology. ; Neuroradiology. ; Neuropsychology.
    Description / Table of Contents: History of Epilepsy Surgery -- Epilepsy: Clinical, Epidemiological, and Therapeutical Aspects -- Presurgical Evaluation -- Surgical Tools and Techniques -- Anesthesia -- Temporal Lobe Resections -- Extratemporal Resections -- Hemispherical Procedures -- Long-Term Epilepsy-Associated Tumors (LEATs) -- MRI-Negative Epilepsies -- Pediatric Epilepsy Surgery -- Reoperations after failed surgery -- Pathology in Epilepsy Surgery -- Non-Resective Epilepsy Surgery -- Complications -- Cost-Effectiveness of Epilepsy Surgery -- The current Place of Epilepsy Surgery -- A personal view.
    Abstract: This book fills the gap between the increasing demand for epilepsy surgical experience and limited training facilities in this area. It comprehensively describes surgical techniques, including tricks and pitfalls, based on the author’s 30 years of experience, providing optimal and effective training for young neurosurgeons by avoiding learning by trial and error. Moreover, it also includes useful information for epileptologists and other professionals involved in the epilepsy surgical program to allow them to gain a better understanding of possibilities and limitations of epilepsy surgery. .
    Type of Medium: Online Resource
    Pages: XXI, 404 p. 154 illus., 111 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030487485
    URL: https://doi.org/10.1007/978-3-030-48748-5
    DOI: 10.1007/978-3-030-48748-5
    DDC: 617.48
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  • 18
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    Bioremediation and Biotechnology, Vol 4 : Techniques for Noxious Substances Remediation (2020)
    Cham :Springer International Publishing :
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    Keywords: Conservation biology. ; Ecology . ; Environment. ; Biotechnology. ; Pollution. ; Earth sciences. ; Geography. ; Conservation Biology. ; Environmental Sciences. ; Biotechnology. ; Pollution. ; Earth and Environmental Sciences.
    Description / Table of Contents: Preface -- Concerns and Threats of Heavy Metals Contamination on Aquatic Ecosystem -- Pollution in Aquatic Environs: Sources and consequences -- A Recent Scenario of Groundwater Quality in Northwest Himalaya, India -- Polycyclic aromatic hydrocarbons: Toxic Effects and their Bioremediation Strategies -- Mechanisms and importance of phytoremediation -- Role of Soil Biota and Associated Threats -- Viability of in-situ and ex-situ bioremediation approaches for degradation of noxious substances in stressed environs -- Bioremediation: A viable approach for degradation of petroleum hydrocarbon -- Application of macrophytes for remediation of wastewater in constructed wetlands -- Application of Biotechnology for restoration of degraded environs -- Role of Free Floating Aquatic Macrophytes in abatement of the disturbed Environs -- Genetically Modified Microbes as Biofertilizers -- Nanotechnology: A Modern Waste management approach -- Restoration of Heavy Metal Contaminated Environs through Ectomycorrhizal Symbiosis -- Index.
    Abstract: The rapid thriving of industries, conversion of agricultural land to residential areas, habitat destruction, deforestation and use of recalcitrant synthetic substances enhanced the rate of degradation of the environment. Although there are various conventional techniques for degradation and cleaning of noxious pollutants from disturbed environs, they are energy inefficient and costly to install. Bioremediation has emerged recently as an alternative and novel approach to manage and control environmental pollutants. This volume focuses explicitly on the remediation of noxious substances in stressed environs. It includes expert-contributed chapters on bio-monitoring by way of evaluating the relationship of biota with the polluted/stressed environs, sustainable plant-based degradation of noxious pollutants, and the application of biotechnologies to achieve tailored responses. Academicians, researchers, scientists and students will find this work essential for sustainable treatment of noxious pollutants. This book also serves as a core guide for training, teaching and research in conservation biology and environmental rehabilitation.
    Type of Medium: Online Resource
    Pages: XX, 340 p. 41 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030486907
    URL: https://doi.org/10.1007/978-3-030-48690-7
    DOI: 10.1007/978-3-030-48690-7
    DDC: 333.9516
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  • 19
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    Agricultural, Forestry and Bioindustry Biotechnology and Biodiscovery (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biodiversity. ; Agriculture. ; Forestry. ; Plant biotechnology. ; Plant diseases. ; Energy policy. ; Energy and state. ; Biodiversity. ; Agriculture. ; Forestry. ; Plant Biotechnology. ; Plant Pathology. ; Energy Policy, Economics and Management.
    Description / Table of Contents: Genetically modified organisms (GMOs) impact and current status in Latin America: technological sovereignty or dependence? -- New biotechnology promising approaches for disease control on bananas and plantains -- Complementation of bananas conventional breeding programs through biotechnological genetic improvement -- The stress as inducer of heritable changes in micropropagated banana: the hypothesis of cytokinin accumulation -- Somatic embryogenesis for clonal propagation and associated molecular studies in cacao (Theobroma cacao L.) -- Use of biotechnology in Forestry breeding programs for natural resources and biodiversity conservation; Creating super trees for the future -- Stress modulation in Pinus spp. Somatic embryogenesis as model for climate change mitigation; Stress is not always a problem -- A Protective Role for Accumulated Dry Matter Reserves in Seeds During Desiccation: Implications for Conservation -- Biodiversity in Ecuador and its immense potential for agricultural pest control -- Native biodiversity: a strategic resource to accelerate bioeconomy development in Latin America and the Caribbean -- Low cost crop waste biosorbent technology for removing toxic and pollutants from wastewater -- The status of plant and plant-microbe interactions related to medicinal agents -- Bringing new function to packaging materials by agricultural byproducts -- Use of banana crop wastes to develop products in the aquaculture and plastic sectors -- Use of agroindustrial biomass for biofuels, enzymes discovery and production -- Temperature Profiles during the Fermentation of Cacao ‘Nacional’ to understand chocolate quality -- Ethno Phytopharmacology. Product validation process based on traditional knowledge of medicinal plants -- Biological control as a key tool for the management of invasive species in Latin America and the Caribbean -- Current research on Andean fruit crop diseases -- Biotechnological tools for the development of Foc TR4-resistant or tolerant Musa spp. Cultivars -- Integrated pest management of whitefly crop-free periods can reduce the Begomovirus transmission in tomato.
    Abstract: Food security, crop protection, biodiversity, and human and environmental health are among the main needs and concerns of society. Modern biotechnology and life sciences represent a constantly evolving area that is key for the rational use of natural resources – resources that in turn are indispensable for societal development. This book features the outcomes of the IV International Biotechnology and Biodiversity Congress, held in Guayaquil, Ecuador, 2018. It includes extensive reviews of the trends in agricultural and forestry biotechnology, molecules and materials biodiscovery, ethnomedicine, environmental impact and bioindustry research, describing many of these topics from the Latin America perspective and showing how the biodiversity and ancient knowledge of these countries are vital for worldwide sustainable development. .
    Type of Medium: Online Resource
    Pages: XIX, 460 p. 82 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030513580
    URL: https://doi.org/10.1007/978-3-030-51358-0
    DOI: 10.1007/978-3-030-51358-0
    DDC: 333.95
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  • 20
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    Aging and Hearing : Causes and Consequences (2020)
    Cham :Springer International Publishing :
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    Keywords: Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Description / Table of Contents: Ch 1: Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging -- Ch 2: Genetic and Molecular Aspects of the Aging Auditory System -- Ch 3: The Aging Cochlea and Auditory Nerve -- Ch 4: Age-Related Changes in the Auditory Brainstem and Inferior Colliculus -- Ch 5: Age related changes in the primate auditory cortex -- Ch 6: The Aging Auditory System: Electrophysiology -- Ch 7: Age-Related Changes in Segregation of Sound Sources -- Ch 8: Causes and Consequences of Age-Related Hearing Loss -- Ch 9: Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences -- Ch 10: Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener -- Ch 11: Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention -- Ch 12: Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss.
    Abstract: This volume provides contemporary discussions on new developments in aging research. It serves as an important update on the current state of research on the aging auditory system. Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging Karen S. Helfer and Edward L. Bartlett Genetic and Molecular Aspects of the Aging Auditory System Shinichi Someya and Mi-Jung Kim The Aging Cochlea and Auditory Nerve Kevin K. Ohlemiller and Christopher Spankovich Age-Related Changes in the Auditory Brainstem and Inferior Colliculus Josef Syka Age-Related Changes in the Primate Auditory Cortex Gregg Recanzone The Aging Auditory System: Electrophysiology Kelly C. Harris Age-Related Changes in Segregation of Sound Sources Frederick J. Gallun and Virginia Best Causes and Consequences of Age-Related Hearing Loss Jennifer A. Deal, Nicholas S. Reed, Emily C. Pedersen, and Frank R. Lin Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences Sandra Gordon-Salant, Maureen J. Shader, and Arthur Wingfield Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener Stefanie E. Kuchinsky and Kenneth I. Vaden, Jr. Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention Larry E. Humes, M. Kathleen Pichora-Fuller, and Louise Hickson Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss Robert D. Frisina, Carlos J. Cruz, Tanika T. Williamson, Xiaoxia Zhu, and Bo Ding .
    Type of Medium: Online Resource
    Pages: XVII, 323 p. 62 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030493677
    Series Statement: Springer Handbook of Auditory Research, 72
    URL: https://doi.org/10.1007/978-3-030-49367-7
    DOI: 10.1007/978-3-030-49367-7
    DDC: 612.8
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  • 21
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    Late Cretaceous Dinosaur Eggs and Eggshells of Peninsular India : Oospecies Diversity and Taphonomical, Palaeoenvironmental, Biostratigraphical and Palaeobiogeographical Inferences (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Paleoecology. ; Paleontology . ; Bioinformatics. ; Archaeology. ; Earth sciences. ; Paleoecology. ; Paleontology. ; Computational and Systems Biology. ; Archaeology. ; Earth Sciences.
    Description / Table of Contents: Chapter 1-Introduction -- Chapter 2-Historical perspective -- Chapter 3-Geology and stratigraphy -- Chapter 4-Indian late cretaceous dinosaur nesting sites -- Chapter 5-Discussion. Chapter -- 6-Summary and conclusions.
    Abstract: This book documents analyses of the Late Cretaceous dinosaur nesting sites of the Lameta Formation at Jabalpur, Districts Dhar and Jhabua, Madhya Pradesh; Districts Kheda and Panchmahal (Gujarat); and the Pisdura, Dongargaon and Pavna sectors in the Chandrapur Districts of Maharashtra, which are exposed in India along an east-west and central axis. In this work, special emphasis has been given to the dinosaur nesting sites of the east-central Narbada River region, including its regional geology. The work was undertaken to provide detailed information concerning dinosaur eggs, eggshell fragments, nests and clutches found in the Lameta Formation of peninsular India. Prior to the present work there had been no detailed review of systematic work on the taxonomy, and of micro- and ultrastructural studies of dinosaur eggs and eggshells from the Lameta Formation. The study documents the field and laboratory investigations that facilitated the reconstruction of the morphotaxonomy, models for the burial pattern of eggs and eggshells, taphonomic implications,and the palaeoenvironmental context and palaeoecological conditions during the Late Cretaceous at the time of the extrusion of the Deccan traps, which may have been partly responsible for the extinction of the dinosaurs. The need to follow a parataxonomic classification for Indian dinosaur eggs and eggshell types is very apparent, and this book addresses this aspect in some detail. The emphasis on the application of parataxonomic schemes is based on the description of new oospecies and their comparison with previously known forms. The present work has led to the recovery of numerous nests, many collapsed eggs and hundreds of dinosaur eggshell fragments from the localities situated near the east, west and central Narbada River regions. It will be of interest to academics and professional palaeontologists, and all students of dinosaurs.
    Type of Medium: Online Resource
    Pages: XX, 280 p. 92 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030564544
    Series Statement: Topics in Geobiology ; 51
    URL: https://doi.org/10.1007/978-3-030-56454-4
    DOI: 10.1007/978-3-030-56454-4
    DDC: 560.45
    Language: English
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  • 22
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    Online Resource
    Plant Defence: Biological Control (2020)
    Cham :Springer International Publishing :
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    Keywords: Plant diseases. ; Agriculture. ; Conservation biology. ; Ecology . ; Plant Pathology. ; Agriculture. ; Conservation Biology.
    Description / Table of Contents: I. Biology of Plant defence -- 1.Plant defense in biological pest control -- 2. Specialized metabolites and plant defence -- 3.Sources of variation in defensive traits in Quercus species -- 4.Glycans as Modulators of Plant Defense -- 5.Biological Control and Need of a Strategic Shift -- II. Use of natural compounds -- 6.Polyphenolic Compounds Obtained from OMWW -- 7.small molecules of natural origin -- 8.Pinus polyphenols and antifungal activities -- 9.stilbenoid-enriched grape cane extracts in biocontrol -- III. Use of biological agents -- 10.Biological control of postharvest diseases -- 11.Sorghum allelopathy for sustainable weed management -- 12.Chaetomium as biocontrol agent on plant pathogens -- 13.Fusaria strains as biocontrol agents -- 14. Fungi as biological control -parasitic nematodes -- 15.Control of pepper powdery mildew -- 16.Molecular Mechanisms of Nematode- Microbe Interactions -- VI. Market and commercialization -- 17.Trends for commercialization of Biocontrol Agent.
    Abstract: Insects, pests and weeds are responsible for substantial loss of crops and reduced food supplies, poorer quality of agricultural products, economic hardship for growers and processor. Generally, chemical control methods are neither always economical nor are they effective and may have associated unwanted health, safety and environmental risks. Biological control involves use of beneficial biological agents to control pests and offers an environmental friendly approach to the effective management of plant diseases and weeds. The chapters are written by well recognized group leaders in the field. This book provides a comprehensive account of interaction of host and pests, and development of biological control agents for practical applications in crops management utilizing inherent defence mechanism, induced stimulation and biological control agents. The contents are divided into the following sections: General biology of plant defence, Use of natural compounds for biological control, Use of biological agents, Mechanism of action and Commercial aspects. The book will be useful for academicians, researcher and industries involved in study and manufacturing these products.
    Type of Medium: Online Resource
    Pages: X, 478 p. 72 illus., 54 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030510343
    Series Statement: Progress in Biological Control, 22
    URL: https://doi.org/10.1007/978-3-030-51034-3
    DOI: 10.1007/978-3-030-51034-3
    DDC: 571.92
    Language: English
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    Necrotizing Soft Tissue Infections : Clinical and Pathogenic Aspects (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medical microbiology. ; Diseases. ; Microbiology. ; Medical Microbiology. ; Diseases. ; Microbiology.
    Description / Table of Contents: Chapter 1: The INFECT-project: An international multidisciplinary project on necrotizing soft tissue infections -- Chapter 2: Necrotizing Soft Tissue Infections: case reports from the patients prospective -- Chapter 3: Necrotizing soft tissue infections: Case-reports, from the clinician’s perspectives -- Chapter 4: Necrotizing soft tissue infections: clinical features and diagnostic aspects -- Chapter 5: Microbiological etiology of necrotizing soft tissue infections -- Chapter 6: Beta-hemolytic streptococci and necrotizing soft tissue infections -- Chapter 7: Treatment of necrotizing soft tissue infections: Antibiotics -- Chapter 8: Treatment of necrotizing soft tissue infections: IVIG -- Chapter 9: Pathogenic mechanisms of streptococcal necrotizing soft tissue infections -- Chapter 10: Systems genetics approaches in mouse models of Group A Streptococcal necrotizing soft tissue infections -- Chapter 11: Systems biology and biomarkers in necrotizing soft tissue infections -- Chapter 12: Systems and precision medicine in necrotizing soft tissue infections.
    Abstract: This volume aims to enhance the current understanding of clinical features, treatment and pathogenic aspects in necrotizing soft tissue infections. Various representative case studies are discussed to enhance the readers’ understanding of these complex diseases. Necrotizing soft tissue infections are rapidly spreading infections that may cause extensive soft tissue or limb loss, multiorgan failure and are associated with a considerable fatality rate. It is undisputed that rapid diagnosis and prompt intervention is directly related to survival. The initial presentation may be limited to unspecific symptoms such as tenderness, swelling, erythema and pain. Thus, diagnosis and management are challenging due to heterogeneity in clinical presentation, in co-morbidities, in microbiological aetiology, as well as in the pathogenic mechanisms. An international and multidisciplinary consortium, INFECT, has for the last 6 years been pursuing research aimed to advance the understanding of the clinical and pathogenic aspects of these infections. A central part has been to create a comprehensive clinical registry and associated biobank which have also formed the basis for the experimental studies. Using the INFECT patient cohort, as well as an integrated systems biology approach in patients and clinically relevant experimental models, an advanced insight of diagnostic features, causative microbial agents, treatment strategies, and pathogenic mechanisms (host and bacterial disease traits and their underlying interaction network) has been obtained.
    Type of Medium: Online Resource
    Pages: VIII, 207 p. 60 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030576165
    Series Statement: Advances in Experimental Medicine and Biology, 1294
    URL: https://doi.org/10.1007/978-3-030-57616-5
    DOI: 10.1007/978-3-030-57616-5
    DDC: 616.9041
    Language: English
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  • 24
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    Online Resource
    Tumor Microenvironment : Molecular Players – Part B (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Internal medicine. ; Cancer Microenvironment. ; Cancer Biology. ; Cell Biology. ; Internal Medicine.
    Description / Table of Contents: MicroRNAs in the tumor microenvironment -- The Impact of Estrogen in the Tumor Microenvironment -- The non-bone related role of RANK/RANKL signaling in cancer -- Modulation of Cancer Cell Growth and Progression by Caveolin-1 in the Tumor Microenvironment -- Exosomes: Novel Players of Therapy Resistance in Neuroblastoma -- COX-2 Signaling in the Tumor Microenvironment -- Renin–angiotensin system in the tumor microenvironment -- Stem cell secreted factors in the tumor microenvironment -- Tight interplay between therapeutic monoclonal antibodies and the tumor microenvironment in cancer therapy -- Tumor Microenvironment & Nitric Oxide: Concepts and Mechanisms -- Index.
    Abstract: This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including MicroRNAs, estrogen, Caveolin-1, Nitric Oxide, RANK/RANKL signaling, , COX-2 Signaling, Renin–angiotensin system, and more. Taken alongside its companion volumes, Tumor Microenvironment: Molecular Players – Part B updates us on what we know about the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIV, 162 p. 22 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030502249
    Series Statement: Advances in Experimental Medicine and Biology, 1277
    URL: https://doi.org/10.1007/978-3-030-50224-9
    DOI: 10.1007/978-3-030-50224-9
    DDC: 571.978
    Language: English
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  • 25
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    Online Resource
    Soil Health on the Farm, Ranch, and in the Garden (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Conservation biology. ; Ecology . ; Agriculture. ; Environmental health. ; Botany. ; Landscape ecology. ; Conservation Biology. ; Agriculture. ; Environmental Health. ; Plant Science. ; Landscape Ecology.
    Description / Table of Contents: Chapter1. Taming the Land, A Historical Perspective -- Chapter2. The Ecological Connection in Farming, Ranching, and Gardening -- Chapter3. Hydrology and Erosion Processes -- Chapter4. Cover Crop Dynamics on Hydrology and Erosion -- Chapter5. Vegetation Effects on Hydrology and Erosion: Grazinglands -- Chapter6. Organic Matter: The Whole Truth and Nothing but the Truth -- Chapter7. Soil-Hydrology-Plant Assessment Technologies for Cropland, Rangeland, Pastureland, and Gardens.
    Abstract: This book explores the importance of soil health in croplands, rangelands, pasturelands, and gardens, and presents new methods and technologies for assessing soil dynamics and health in these different land types. Through perspectives of agriculture, soil management, and ecological sustainability, the book provides accurate and up-to-date information on soil health assessment and maintenance that is often missing from current literature on conservation and environmental management and preservation. The book is written in a clear and concise format, and will appeal to non-scientists interested in soil health, as well as professional farmers, ranchers and gardeners. The book begins by discussing soil health from a historical perspective, and in terms of how it is covered in the news currently. Then the author addresses the ecological implications of soil health in farming, ranching and gardening, and comprehensively details the physical, chemical and biological properties of soil as they apply in various land types. The book then examines soil health assessment using new diagnostic and analytic technologies, and how these new innovations will be necessary going forward to maintain and improve soil health. .
    Type of Medium: Online Resource
    Pages: IX, 370 p. 119 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030403980
    URL: https://doi.org/10.1007/978-3-030-40398-0
    DOI: 10.1007/978-3-030-40398-0
    DDC: 333.9516
    Language: English
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  • 26
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    Online Resource
    Physiology of Human Female Lactation (2021)
    Cham :Springer International Publishing :
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    Keywords: Human physiology. ; Reproduction. ; Physiology. ; Anatomy. ; Cytology. ; Human Physiology. ; Reproductive Physiology. ; Anatomy. ; Cell Biology.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Origin and development of the breast -- Chapter 3: Structure of the lactating breast -- Chapter 4: Breast function during the initial period of lactation (lactogenesis I and II) -- Chapter 5: The period of established lactation (lactogenesis III).
    Abstract: This comprehensive Monograph examines all peripheral and central mechanisms of regulating the secretion of milk from the lactating breast. The author reviews the complete female breast development, starting with the early childhood, up to pregnancy and lactation. Structural and ultrastructural data on the alveolar-ductal system, together with details of breast innervation, are used to investigate the physiological process of lactation. Readers will appreciate the special focus on reflexes, both in the child and the mother, that help to regulate maternal milk production and secretion. Following this, the author sheds a light on the composition and dynamics of milk components during the different periods of lactation. The final section of this volume focusses on practical aspects of modern breastfeeding, like the use of breast pumps or galactogogues, to influence the productivity of milk production. These fundamental principles and structural details will be particularly useful for physiologists and clinicians working in gynecology and pediatrics.
    Type of Medium: Online Resource
    Pages: VIII, 254 p. 87 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030663643
    URL: https://doi.org/10.1007/978-3-030-66364-3
    DOI: 10.1007/978-3-030-66364-3
    DDC: 612
    Language: English
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  • 27
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    Online Resource
    Emulsion‐based Encapsulation of Antioxidants : Design and Performance (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Food Microbiology. ; Food science. ; Food Microbiology. ; Food Science.
    Description / Table of Contents: Chapter One Why encapsulate antioxidants in emulsion-based systems, where they are located, and how location affects their efficiency -- Chapter Two High-energy emulsification methods for encapsulation of lipid-soluble antioxidants -- Chapter Three Low-energy emulsification methods for encapsulation of antioxidants -- Chapter Four Nanoemulsions as carriers for natural antioxidants: formulation development and optimization -- Chapter Five Microemulsions as antioxidant carriers -- Chapter Six Membrane emulsification for encapsulation of bioactives: Application to the encapsulation of antioxidants -- Chapter Seven Encapsulation of antioxidants using double emulsions -- Chapter Eight Stability and release behavior of bioactive compounds (with antioxidant activity) encapsulated by Pickering emulsion -- Chapter Nine Advances in the oxidative stability mechanisms of emulsions -- Chapter Ten The role of antioxidants and encapsulation processes in omega-3 stabilization -- Chapter Eleven Encapsulation of pigmented lipophilic antioxidants through micro and nanoemulsions -- Chapter Twelve Characterization techniques for emulsion-based antioxidant carriers with biomedical applications.
    Abstract: The limited aqueous solubility of bioactive pharmaceutical ingredients presents a tremendous challenge in the development of new drugs. In recent years, methods have been developed to protect these sensitive bioactive compounds, namely antioxidants, with the aim of increasing the public sanitation grades. Emulsion-based systems are particularly interesting as colloidal delivery encapsulation systems, because they can easily be created from food-grade ingredients using relatively simple processing protocols. It is one of the most favorable delivery systems to increase the solubility of phytochemicals, nutraceuticals and food additives. Emulsion‐based Encapsulation of Antioxidants: Design and Performance advances the field of colloid science through the investigation of the effects of formulation and process parameters that influence emulsion production. The book offers a deeper comprehension of the technological and biological aspects of the incorporation of encapsulated compounds in food matrices and explication of their activity. Chapters provide an overview of the status of emulsion-based formulations to encapsulate antioxidants, fabrication, properties, applications, and biological fate with emphasis on systems suitable for utilization within industry. Special emphasis is placed on the antioxidant activity of the carriers being the key advantage of these emulsion-based systems. The main aim of the book is to inspire and to guide fellow scientists and students in this field. Filled with illustrations, figures, case studies, practical examples, and historical perspectives, the book can also be used as a practical handbook or graduate textbook. For industry professionals, the book presents easy-to-achieve approaches to industrial pharmaceutical production. .
    Type of Medium: Online Resource
    Pages: XIII, 473 p. 96 illus., 75 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030620523
    Series Statement: Food Bioactive Ingredients,
    URL: https://doi.org/10.1007/978-3-030-62052-3
    DOI: 10.1007/978-3-030-62052-3
    DDC: 664.001579
    Language: English
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    Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications (2021)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    URL: https://doi.org/10.1007/978-3-030-68510-2
    DOI: 10.1007/978-3-030-68510-2
    DDC: 615
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    Enzyme Cascade Design and Modelling (2021)
    Cham :Springer International Publishing :
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    Keywords: Proteins . ; Biotechnology. ; Enzymology. ; Bioorganic chemistry. ; Protein Biochemistry. ; Chemical Bioengineering. ; Enzymology. ; Bioorganic Chemistry.
    Description / Table of Contents: Preface -- Chapter 1: Introduction -- Chapter 2: Enzyme Cascade Design – Retrosynthesis Approach -- Chapter 3 : Multi-Enzymatic Cascades in vitro -- Chapter 4: Multi-Enzymatic Cascades in vivo -- Chapter 5: Chemo-Enzymatic Cascades -- Chapter 6: Enzyme Cascade Kinetic Modelling -- Chapter 7: Enzyme Cascade Reaction Engineering -- Chapter 8: Enzyme Cascade Process Design and Modelling -- Chapter 9: Enzyme Cascade Reaction Monitoring And Control -- Chapter 10: Cascade reactions in non-conventional media -- Chapter 11: Perspectives.
    Abstract: This book provides a comprehensive overview of the recent developments achieved in the field of chemo/enzymatic cascades with topics spanning from design (in vitro and in vivo) to kinetic- and process modelling as well as process control. Opportunities and challenges of building multi-step chemo/enzymatic reactions are discussed, whereby the latter are critically assessed in each chapter and methods to ease the implementation are explored. Both, multi-enzymatic cascades and chemo-enzymatic cascades are presented with the motivation of combining the strengths of these two worlds (e.g. selectivity, activity and robustness) not neglecting the obstacles and challenges of such endeavour. Furthermore, the use of non-conventional media for catalytic cascade reactions, recent achievements and potential for future developments in a technical environment are addressed.
    Type of Medium: Online Resource
    Pages: VII, 181 p. 103 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030657185
    URL: https://doi.org/10.1007/978-3-030-65718-5
    DOI: 10.1007/978-3-030-65718-5
    DDC: 572.6
    Language: English
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    ESR Spectroscopy for Life Science Applications: An Introduction (2021)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Radiology. ; Spectrum analysis. ; Pharmaceutical chemistry. ; Nutrition   . ; Biomedical Research. ; Radiology. ; Spectroscopy. ; Pharmaceutics. ; Nutrition.
    Description / Table of Contents: Ch 1: Electron Spin Resonance- An Introdcution -- Ch 2: ESR – Applications in Healthcare and Pharmaceutical Science -- Ch 3: ESR Applications in Paleontology and Geochronology -- Ch 4: ESR Applications in Food Science.
    Abstract: This book introduces the audience with basic theoretical and experimental aspects of Electron Spin Resonance (ESR) Spectroscopy. It further talks about ESR spectroscopy applications in Healthcare & Pharmaceutical Science, Paleontology & Geochronology and Food Science. Mathematical details have been kept to a necessary minimum and emphasis is given to highlight the applications of the technique.
    Type of Medium: Online Resource
    Pages: X, 72 p. 32 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030641986
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-64198-6
    DOI: 10.1007/978-3-030-64198-6
    DDC: 610.72
    Language: English
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    Organotypic Models in Drug Development (2021)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Description / Table of Contents: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Abstract: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Type of Medium: Online Resource
    Pages: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030700638
    Series Statement: Handbook of Experimental Pharmacology, 265
    URL: https://doi.org/10.1007/978-3-030-70063-8
    DOI: 10.1007/978-3-030-70063-8
    DDC: 615
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    Bioremediation and Biotechnology, Vol 2 : Degradation of Pesticides and Heavy Metals (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Conservation biology. ; Ecology . ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Water. ; Hydrology. ; Sustainability. ; Applied ecology. ; Agriculture. ; Conservation Biology. ; Environmental Engineering/Biotechnology. ; Water. ; Sustainability. ; Applied Ecology. ; Agriculture.
    Description / Table of Contents: Preface -- 1. Causes and Effects of Pesticide and Metal Pollution on Different Ecosystems -- 2. Ecotoxicology of Heavy Metals: Sources, Effects and Toxicity -- 3. Role of Modern Innovative Techniques for Assessing and Monitoring Heavy Metal and Pesticide Pollution in Different Environments -- 4. Global Scenario of Remediation Techniques to Combat Pesticide Pollution -- 5. Mycoremediation: A Sustainable Approach for Pesticide Pollution Abatement -- 6. Bio-pesticides: Application and Possible Mechanism of Action -- 7. Values of Biofertilizers for Sustainable Management in Agricultural Industries -- 8.Role of Macrophytes in Spontaneous Lacustrine Phytofiltration -- 9. Phytoremediation of Heavy Metals Using Salix (Willows) -- 10. Photo catalysis: An Effective Tool for Treatment of Dyes Contaminated Wastewater -- 11. Removal of dyes from waste water by Micellar Enhanced Ultrafiltration -- 12. Biofilm: an innovative modern technology for aquatic pollution remediation -- 13. Heavy Metal Soil Contamination and Bioremediation -- 14. Environmental Biotechnology: For Sustainable Future -- 15. Global Environmental Regulations for Management of Pesticides -- Index.
    Abstract: This book addresses the grave concerns stemming out due to conventional treatment techniques. The main focus of this book revolves round the central kernel of novel technology (bioremediation and biotechnology) which has emerged as an independent warrior to clean up and restore the disturbed environs. Furthermore, this book is a coherent assortment of diverse chapters relevant to the role of biotechnology and bioremediation for restoration of the ecosystems degraded by pesticide and heavy metal pollution. The inaugural chapters deal with the quantification of problem and its magnitude due to pesticides and heavy metals, followed by innovative modern biotechnological and bioremediation treatment technologies and sustainable techniques to remediate the persistent pollutants. It is a detailed comprehensive account for the treatment technologies from unsustainable to sustainable. Academicians, researchers and students shall find it as a complete wrap up regarding biotechnological intervention for sustainable treatment of pollution and shall suffice for the diverse needs of teaching and research.
    Type of Medium: Online Resource
    Pages: XVI, 278 p. 38 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030403331
    URL: https://doi.org/10.1007/978-3-030-40333-1
    DOI: 10.1007/978-3-030-40333-1
    DDC: 333.9516
    Language: English
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    Microbial Cyclic Di-Nucleotide Signaling (2020)
    Cham :Springer International Publishing :
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    Keywords: Bacteria. ; Biomaterials. ; Nucleic acids. ; Proteins. ; Medical microbiology. ; Bacteria. ; Nucleic Acid. ; Proteins. ; Medical Microbiology.
    Description / Table of Contents: Part I:Biochemistry/Structural Biology – Enzymes -- Chapter 1: Cyclic Dinucleotide Signaling In Mycobacteria -- Chapter 2: Structure and regulation of EAL domain proteins -- Chapter 3: Insights into the molecular basis of biofilm dispersal from crystal structures of di-domain containing proteins -- Chapter 4: Structure and function of HD-GYP phosphodiesterases -- Chapter 5: A unified catalytic mechanism for c-di-NMP hydrolysis by DHH/DHHA1 phosphodiesterases -- Chapter 6: Enzymatic degradation of linear dinucleotide intermediates of cyclic dinucleotides -- Part II:Biochemistry/Structural Biology – Receptors -- Chapter 7: Detection of cyclic dinucleotide binding proteins -- Chapter 8: Non-canonical c-di-GMP binding modes -- Part III:Biochemistry/Structural Biology – Sensing -- Chapter 9: Sensory domains that control cyclic di-GMP-modulating proteins: a critical frontier in bacterial signal transduction -- Part IV:Cyclic di-AMP biochemistry and physiology -- Chapter 10: Metabolic regulation by cyclic di-AMP signaling -- Chapter 11: Osmoregulation via cyclic-di-AMP signaling -- Part V:Population diversity -- Chapter 12: Measuring individual cell c-di-GMP: Identifying population diversity and c-di-GMP heterogeneity.-Part VI:Cyclic di-GMP and exopolysaccharide regulation -- Chapter 13: Activation of bacterial cellulose biosynthesis by cyclic-di-GMP -- Chapter 14: The Regulation of Alginate Biosynthesis viaC-di-GMPSignaling -- Part VII:Environmental bacteria -- Chapter 15: Cyclic di-GMP Signaling in Bacillus subtilis -- Chapter 16: C-di-GMP signaling systems in the Gram-positive Bacillus cereus group -- Chapter 17: Cyclic-di-AMP in Bacillus subtilisbiofilm formation.-Chapter 18: Regulation by c-di-GMP in Myxococcusxanthus -- Chapter 19: Light-regulated nucleotidesecond messenger signalingin cyanobacteria -- Chapter 20: C-di-GMP-dependent regulation of antibiotic biosynthesis in Lysobacter -- Chapter 21: Cyclic di-GMP signalingin extreme acidophilic bacteria -- Part VIII:Pathogens -- Chapter 22: Signals modulating cyclic di-GMP pathways in Vibrio cholera -- Chapter 23: Cyclic di-GMP regulation of gene expression -- Chapter 24: Cyclic di-GMP signaling in Salmonella enterica serovar Typhimurium -- Chapter 25: Cyclic di-GMP signaling in the phytopathogen Xanthomonas campestris pv. Campestris -- Chapter 26: Cyclic di-AMP in Mycobacterium tuberculosis -- Chapter 27: Cyclic di-AMP signaling in Streptococcus pneumonia -- Part IX:Gram-negative bacteria -- Chapter 28: Regulation of cyclic-di-GMP signaling in Pseudomonas aeruginosa -- Chapter 29: Unconventional Cyclic di-GMPSignalling in Escherichia coli -- Chapter 30: Cyclic di-GMP in Burkholderia spp -- Chapter 31: Cyclic di-GMP and the regulation of biofilm dispersion -- Part X:Cyclic di-GMP signaling in eukaryotes -- Chapter 32: Cyclic-di-GMP activates adenylate cyclase A and protein kinase A to induce stalk formationin Dictyostelium -- Part XI:Interference Strategies -- Chapter 33: Targeting cyclic di-nucleotide signaling with small molecules -- Part XII:Novel cyclic di-nucleotides -- Chapter 34: Cyclic di-GMP signaling gone astray: cGAMP signaling via Hypr GGDEF and HD-GYP enzymes -- Chapter 35: Microbial cyclic GMP-AMP signaling pathways.-Part XIII:Honorary cyclic nucleotides -- Chapter 36: 2’,3’-cyclic mononucleotide metabolism and possible roles in bacterial physiology -- Part XIV:Horizontal gene transfer -- Chapter 37: Horizontal transfer of c-di-GMP associated genes. Theoretical underpinnings and future perspectives.-Part XV:Conclusion -- Chapter 38: Conclusion. .
    Abstract: This book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical characteristics of multiple turnover enzymes and receptors. The respective chapters discuss the commonalities and diversity of cyclic di-GMP, cyclic di-AMP and recently discovered cyclic GMP-AMP signaling systems in manifold Gram-negative and Gram-positive bacteria. The global human pathogens Mycobacterium tuberculosis, Vibrio cholerae, Salmonella typhimurium, Escherichia coli and Streptococcus pneumoniae, the facultative human pathogen Pseudomonas aeruginosa, global plant pathogens as exemplified by Xanthomonas campestris and Burkholderia spp., and the omnipresent probiotic Lactobacilli, as well as environmentally important photoautotrophic cyanobacteria, the multicellular Myxococcus xanthus, and chemolithotrophic Acidithiobacillus are among the representatives of the microbial kingdom that are described. In turn, the various aspects of bacterial physiology affected by these signaling systems– e.g. biofilm formation and dispersal, the cell cycle, motility, virulence, production of antimicrobials, fundamental metabolism and osmohomeostasis – are discussed in detail in the context of different microorganisms. Dedicated chapters focus on the population diversity of cyclic dinucleotide signaling systems, their tendency to be horizontally transferred, the cyclic di-GMP signaling system in the social amoeba Dictyostelium, honorary cyclic (di)nucleotides, and the development of strategies for interfering with cyclic dinucleotide signaling in order to manipulate microbial behavior. Taken together, the chapters provide an authoritative source of information for a broad readership: beginners and advanced researchers from various disciplines; individuals seeking a broad overview of cyclic di-nucleotide signaling; and those who want to learn more about specific aspects. Also featuring reviews with a forward-looking perspective, the book offers a valuable source of inspiration for future research directions.
    Type of Medium: Online Resource
    Pages: XVIII, 657 p. 108 illus., 96 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030333089
    URL: https://doi.org/10.1007/978-3-030-33308-9
    DOI: 10.1007/978-3-030-33308-9
    DDC: 579.3
    Language: English
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    Online Resource
    Progress in Botany Vol. 81 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Forestry. ; Botanical chemistry. ; Biotic communities. ; Plant genetics. ; Plant physiology. ; Plant Science. ; Forestry. ; Plant Biochemistry. ; Ecosystems. ; Plant Genetics. ; Plant Physiology.
    Description / Table of Contents: 1. Nitrogen and Sulfur Metabolism in Microalgae and Plants: 50 Years of Research -- 2. Progress Toward Deep Sequencing-Based Discovery of Stress-Related MicroRNA in Plants and Available Bioinformatics Tools -- 3. Recent Advances in MS-Based Plant Proteomics: Proteomics Data Validation Through Integration with Other Classic and -Omics Approaches -- 4. Membrane Trafficking and Plant Signaling -- 5. Molecular Aspects of Iron Nutrition in Plants -- 6. Urea in Plants: Metabolic Aspects and Ecological Implications -- 7. Biosynthesis and Regulation of Secondary Cell Wall -- 8. Stress-Induced Microspore Embryogenesis in Crop Plants: Cell Totipotency Acquisition and Embryo Development -- 9. Potential of Microalgae Biomass for the Sustainable Production of Bio-commodities -- 10. Crassulacean Acid Metabolism and Its Role in Plant Acclimatization to Abiotic Stresses and Defence Against Pathogens -- 11. The Role of the Shikimate and the Phenylpropanoid Pathways in Root-Knot Nematode Infection -- 12. Functional Diversity of Photosynthesis, Plant-Species Diversity, and Habitat Diversity -- 13. When the Tree Let Us See the Forest: Systems Biology and Natural Variation Studies in Forest Species -- 14. The Ecological Importance of Winter in Temperate, Boreal, and Arctic Ecosystems in Times of Climate.
    Abstract: With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on plant physiology, biochemistry, genetics and genomics, forests, and ecosystems.
    Type of Medium: Online Resource
    Pages: XIII, 399 p. 47 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030363277
    Series Statement: Progress in Botany, 81
    URL: https://doi.org/10.1007/978-3-030-36327-7
    DOI: 10.1007/978-3-030-36327-7
    DDC: 580
    Language: English
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    Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. Introduction Food and Brain -- 2. Food and Behavior -- 3. Food and Psychological Wellbeing -- 4. Food and Cognition -- 5. Autism and Food -- 6. Healthy Brains: Types of Food and their Active Pharmacological Ingredients -- 5. Dieting: Importance of Diet and Diet Types -- 6. Nutrigenomics -- 7. Epigenetics -- 8. Gut Microbiota (microbiome) -- 9. Personalized Nutrition -- 10. Vegetables -- 11. Fruits -- 12. Nuts, Seeds and Spices -- 13. Grains [Oats, Barley & Quinoa] -- 14. Seafood [fish like Salmon, Oyster, Sea vegetables (algae)] -- 15. Other -- 16. Autism Management through Food and Diet -- 17. Personalized Nutrition Therapy.
    Abstract: The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.
    Type of Medium: Online Resource
    Pages: XX, 693 p. 111 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030304027
    Series Statement: Advances in Neurobiology, 24
    URL: https://doi.org/10.1007/978-3-030-30402-7
    DOI: 10.1007/978-3-030-30402-7
    DDC: 612.8
    Language: English
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    Conservation Biology : Foundations, Concepts, Applications (2020)
    Cham :Springer International Publishing :
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    Keywords: Biodiversity. ; Animal migration. ; Conservation biology. ; Ecology . ; Animal culture. ; Biodiversity. ; Animal Migration. ; Conservation Biology. ; Animal Science.
    Description / Table of Contents: Foreword -- Preface -- Acknowledgements -- About the Authors -- List of Reviewers -- Chapter 1. The History and Distinctions of Conservation Biology -- Chapter 2. Biodiversity: Concept, Measurement, and Management -- Chapter 3. Human Presence and the Need for Conservation -- Chapter 4. Climate Change and its Impact on Conservation -- Chapter 5. Conservation Genetics -- Chapter 6. The Conservation of Populations: Theory, Analysis, Application -- Chapter 7. The Conservation of Terrestrial Habitat and Landscapes -- Chapter 8. The Conservation of Aquatic Systems -- Chapter 9. Conservation Through Ecosystem Management -- Chapter 10. Values and Ethics in Conservation -- Chapter 11. Conservation Economics and Sustainable Development -- Chapter 12. The Legal Foundations of Conservation Biology -- Chapter 13. Conservation as Vocation -- Index.
    Abstract: This book provides a thorough, up-to-date examination of conservation biology and the many supporting disciplines that comprise conservation science. In this, the Third Edition of the highly successful Conservation Biology: Foundations, Concepts, Applications, the authors address their interdisciplinary topic as it must now be practiced and perceived in the modern world. Beginning with a concise review of the history of conservation, the authors go on to explore the interplay of conservation with genetics, demography, habitat and landscape, aquatic environments, and ecosystem management, and the relationship of all these disciplines to ethics, economics, law, and policy. An entirely new chapter, The Anthropocene: Conservation in a Human-Dominated Nature, breaks new ground in its exploration of how conservation can be practiced in anthropogenic biomes, novel ecosystems, and urban habitats. The Third Edition includes the popular Points of Engagement discussion questions used in earlier editions, and adds a new feature: Information Boxes, which briefly recap specific case histories described in the text. A concluding chapter offers insight into how to become a conservation professional, in both traditional and non-traditional roles. The authors, Fred Van Dyke and Rachel Lamb, draw on their expertise as field biologists, wildlife managers, consultants to government and industry, and scholars of environmental law, policy, and advocacy, as well as their many years of effective teaching experience. Informed by practical knowledge and acquired skills, the authors have created a work of exceptional clarity and readability which encompasses both systemic foundations as well as contemporary developments in the field. Conservation Biology: Foundations, Concepts, Applications will be of invaluable benefit to undergraduate and graduate students, as well as to working conservation scientists and managers. This is an amazing resource for students, faculty, and practitioners both new and experienced to the field. Diane Debinski, PhD Unexcelled wisdom for living at home on Wonderland Earth, the planet with promise, destined for abundant life. Holmes Rolston, PhD Van Dyke and Lamb have maintained the original text’s emphasis on connecting classical ecological and environmental work with updated modern applications and lucid examples. But more importantly, the third edition contains much new material on the human side of conservation, including expanded treatments of policy, economics, and climate change. Tim Van Deelen, PhD Fred Van Dyke and Rachel Lamb break new ground in both the breadth and depth of their review and analysis of this crucially important and rapidly changing field. Any student or other reader wishing to have a comprehensive overview and understanding of the complexities of conservation biology need look no further – this book is your starting point! Simon N. Stuart, PhD.
    Type of Medium: Online Resource
    Pages: XXXI, 613 p. 360 illus., 233 illus. in color. , online resource.
    Edition: 3rd ed. 2020.
    ISBN: 9783030395346
    URL: https://doi.org/10.1007/978-3-030-39534-6
    DOI: 10.1007/978-3-030-39534-6
    DDC: 333.95
    Language: English
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    Environmental Science - A Ground Zero Observation on the Indian Subcontinent (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biodiversity. ; Physical geography. ; Biotic communities. ; Pollution. ; Ecology . ; Biodiversity. ; Physical Geography. ; Ecosystems. ; Pollution. ; Terrestial Ecology.
    Description / Table of Contents: Chapter 1 Introduction to Environment -- Chapter 2 Components of the Earth -- Chapter 3 Earth and its Resources -- Chapter 4 Basics of Ecosystem -- Chapter 5 Major Biochemical Cycles -- Chapter 6 Biodiversity and its Conservation -- Chapter 7 Air Pollution and its Mitigation -- Chapter 8 Pollution and its Mitigation -- Chapter 9 Soil Pollution and its Mitigation -- Chapter 10 Oil Pollution -- Chapter 11 Human Population and the Environment -- Chapter 12 Climate Change: Threat of Era.
    Abstract: This book provides a cross-sectoral, multi-scale assessment of different environmental problems via in-depth studies of the Indian subcontinent. Data collected from different ecosystems forms a strong foundation to explore the topics discussed in this book. The book investigates how mankind is presently under the appalling shadow of pollution, climate change, overpopulation and poverty. The continuing problem of pollution, loss of forests, disposal of solid waste, deterioration of environment, global warming and loss of biodiversity have made nations aware of environmental issues. Many countries are desperately trying to move away from this adverse situation through technological development and policy level approaches. Through a number of case studies the authors provide details of ground level observations of the most environmentally stressed regions in the Indian subcontinent and beyond.
    Type of Medium: Online Resource
    Pages: XIV, 478 p. 338 illus., 175 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030491314
    URL: https://doi.org/10.1007/978-3-030-49131-4
    DOI: 10.1007/978-3-030-49131-4
    DDC: 333.95
    Language: English
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    The Major Metaphors of Evolution : Darwinism Then and Now (2020)
    Cham :Springer International Publishing :
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    Keywords: Evolution (Biology). ; Science History. ; Science Philosophy. ; Evolutionary Biology. ; History of Science. ; Philosophy of Science.
    Description / Table of Contents: Chapter 1: Context -- Chapter 2: A Talking Book -- Chapter 3: Setting the Stage -- Chapter 4: Neo-Darwinism, Expansion and Consolidation (1900-1980) -- Chapter 5: Criticism, Resistance, a Glimmer of Hope -- Chapter 6: Buying Time -- Chapter 7: Making Space -- Chapter 8: Conflict Resolution -- Chapter 9: Evolutionary Transitions -- Chapter 10: The Stockholm Paradigm -- Chapter 11: Putting Evolution to Work.
    Abstract: This book presents a unified evolutionary framework based on three sets of metaphors that will help to consolidate discussions on evolutionary transitions. Evolution is the unifying principle of life, making identifying ways to apply evolutionary principles to tackle existence-threatening crises such as climate change crucial. A more cohesive evolutionary framework will further the discussions in this regard and also accelerate the process itself. This book lays out a framework based on three dualistic classes of metaphors – time, space, and conflict resolution. Evolutionary transitions theory shows how metaphors can help us understand selective diversification, as Darwin described with his “tree of life”. Moreover, the recently proposed Stockholm paradigm demonstrates how metaphors can help shed light on the emergence of complex ecosystems that Darwin highlighted with his “tangled bank” metaphor. Taken together, these ideas offer proactive measures for coping with existential crises for humanity, such as climate change. The book will appeal to biologists, philosophers and historians alike.
    Type of Medium: Online Resource
    Pages: XVII, 273 p. 33 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030520861
    Series Statement: Evolutionary Biology – New Perspectives on Its Development, 2
    URL: https://doi.org/10.1007/978-3-030-52086-1
    DOI: 10.1007/978-3-030-52086-1
    DDC: 576.8
    Language: English
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    The Spruce Genome (2020)
    Cham :Springer International Publishing :
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    Keywords: Plant genetics. ; Plant biotechnology. ; Forestry. ; Plant Genetics. ; Plant Biotechnology. ; Forestry.
    Description / Table of Contents: Introduction -- The White spruce genome -- Targeted and whole genome re-sequencing for population and evolutionary genomic inferences in Norway spruce -- Transposable elements in Spruce -- An intact, but dormant LTR retrotransposon defines a moderately-sized family in white spruce (Picea glauca) -- The DNA methylome of Norway spruce -- Epigenomics in Norway spruce -- Comparative Genomics of Spruce -- Comparative genomics with the comparisons of BACs between loblolly pine and white spruce -- Wood formation and genomic selection in white spruce, data imputation strategies -- Ecotypes in Norway spruce (“Genomics of adaptation to drought across the Central European range of Norway spruce“) -- Local adaptation in the interior spruce hybrid complex -- Genomics of secondary metabolism - Terpenoids in spruce (Evolutionary dynamics of TPS gene family in Chinese spruce) -- Lignin biosynthesis in Norway spruce as an anti-fungal defense -- Future prospects.
    Abstract: This book offers comprehensive information on the genomics of spruces (Picea spp.), naturally abundant conifer tree species that are widely distributed in the Northern Hemisphere. Due to their tremendous ecological and economic importance, the management of forest genetic resources has chiefly focused on conservation and tree improvement. A draft genome sequence of the 20-gigabase Norway spruce genome was published in the journal Nature in 2013. Continuous efforts to improve the spruce genome assembly are underway, but are hindered by the inherent characteristics of conifer genomes: high amounts of repetitive sequences (introns and transposable elements) in the genome and large gene family expansions with regards to abiotic stress, secondary metabolism and spruces' defense responses to pathogens and herbivory. This book presents the latest information on the status of genome assemblies, provides detailed insights into transposable elements and methylation patterns, and highlights the extensive genomic resources available for inferring population genomics and climate adaptation, as well as emerging genomics tools for tree improvement programs. In addition, this volume features whole-genome comparisons among conifer species, and demonstrates how functional genomics can be used to improve gene function annotations. The book closes with an outlook on emerging fields of research in spruce genomics.
    Type of Medium: Online Resource
    Pages: XIV, 218 p. 48 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030210014
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-21001-4
    DOI: 10.1007/978-3-030-21001-4
    DDC: 581.35
    Language: English
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    Vaccination Strategies Against Highly Variable Pathogens (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human physiology. ; Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human Physiology.
    Description / Table of Contents: Successful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
    Abstract: Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .
    Type of Medium: Online Resource
    Pages: VII, 180 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030580049
    Series Statement: Current Topics in Microbiology and Immunology, 428
    URL: https://doi.org/10.1007/978-3-030-58004-9
    DOI: 10.1007/978-3-030-58004-9
    DDC: 615
    Language: English
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    Druggable Lipid Signaling Pathways (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Pharmacology. ; Medical genetics. ; Cancer. ; Lipids. ; Biomedical Research. ; Pharmacology. ; Medical Genetics. ; Cancer Biology. ; Lipidology.
    Description / Table of Contents: Preface -- Introduction of Druggable Lipid Signaling Pathway -- Biosynthetic Enzymes of Membrane Glycerophospholipid Diversity as Therapeutic Targets for Drug Development -- Druggable Prostanoid Pathway -- Targeting Leukotrienes as a Therapeutic Strategy to Prevent Comorbidities Associated with Metabolic Stress -- Epoxy Fatty Acids are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indications Characterized by Mitochondrial Dysfunction, Endoplasmic Stress and Inflammation -- Druggable Sphingolipid Pathway -- Druggable Lysophospholipid Pathway -- Druggable targets in endocannabinoid signaling -- Drugging the phosphoinositide 3-kinase (PI3K) and phosphatidylinositol 4-kinase (PI4K) family of enzymes for treatment of cancer, immune disorders, and viral/parasitic infections -- Druggable Lipid GPCRs: Past, Present, and Prospects. .
    Abstract: This edited work presents a series of reviews focusing on Druggable Lipid Signaling Pathways. It enables researchers in both academic institutions and industry as well as physicians to understand historical aspects of lipid signaling and future directions of drug discovery targeting lipid signaling pathways. This book provides 9 pathways including acyltransferases, prostanoids, leukotrienes, epoxy fatty acids, sphingolipids, lysophospholipids, endocannabinoids, phosphoinositides, and lipid GPCRs. Readers will discover the importance of each lipid signaling pathway that contributes to broad range of diseases including neurological and neuropsychiatric diseases, pain, metabolic syndromes, cardiovascular diseases, cancer, dermatological diseases, fibrosis, inflammation, etc. Also, readers will recognize that many drugs targeting lipid signaling have been clinically used. Drugs currently under development are also discussed in each chapter, which includes some information about clinical trials and strategic drug designs. .
    Type of Medium: Online Resource
    Pages: VI, 260 p. 33 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506216
    Series Statement: Advances in Experimental Medicine and Biology, 1274
    URL: https://doi.org/10.1007/978-3-030-50621-6
    DOI: 10.1007/978-3-030-50621-6
    DDC: 610.72
    Language: English
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    Fungi in Fuel Biotechnology (2020)
    Cham :Springer International Publishing :
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    Keywords: Fungi. ; Mycology. ; Microbiology. ; Plant biotechnology. ; Renewable energy sources. ; Biology Technique. ; Plant diseases. ; Fungi. ; Plant Biotechnology. ; Microbiology. ; Renewable Energy. ; Biological Techniques. ; Plant Pathology.
    Description / Table of Contents: Preface -- Biofuels: challenges and the promises of fungi in biofuel production -- Plant pathogenic fungi for bioethanol production: mechanisms of actions -- Plant pathogenic fungi for biodiesel production -- Plant pathogenic fungi for VOCs production -- Plant probiotic fungi as a new source for Bioethanol Production -- Endophytic fungi for biofuel production -- Brown and white rot fungi for biofuel production -- Gut fungi for biofuel production -- Consolidated bioprocessing: highly efficient fungi for biofuel production -- Process design in fungal-based biofuel production systems -- Life cycle assessment (LCA) of fungal-based biofuel production systems -- Thermodynamics aspects of fungal-based biofuel production systems -- Modeling and optimization to enhance fungal-based biofuel production -- Index.
    Abstract: Due to the huge quantity and diverse nature of their metabolic pathways, fungi have great potential to be used for the production of different biofuels such as bioethanol, biobutanol, and biodiesel. This book presents recent advances, as well as challenges and promises, of fungal applications in biofuel production, subsequently discussing plant pathogenic fungi for bioethanol and biodiesel production, including their mechanisms of action. Additionally, this book reviews biofuel production using plant endophytic fungi, wood-rotting fungi, fungal biocontrol agents, and gut fungi, and it investigates highly efficient fungi for biofuel production and process design in fungal-based biofuel production systems. Finally, life cycle assessment of fungal-based biofuel production systems are discussed in this volume.
    Type of Medium: Online Resource
    Pages: XI, 233 p. 35 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030444884
    Series Statement: Fungal Biology,
    URL: https://doi.org/10.1007/978-3-030-44488-4
    DOI: 10.1007/978-3-030-44488-4
    DDC: 579.5
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    Problematic Wildlife II : New Conservation and Management Challenges in the Human-Wildlife Interactions (2020)
    Cham :Springer International Publishing :
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    Keywords: Animal migration. ; Conservation biology. ; Ecology . ; Urban ecology (Biology). ; Animal Migration. ; Conservation Biology. ; Urban Ecology.
    Description / Table of Contents: Preface -- Part 1. Introduction to 'Problematic Wildlife II'. Problematic species are increasing, in a world that is constantly changing -- Chapter 1. The need and relevance of the book. Problematic Wildlife and the Modern World -- Part 2. From direct danger to humans to negative impact on human activities -- Chapter 2. Large Felid Predators and ‘Man-eaters’: Can we successfully balance conservation of endangered apex predators with the safety and needs of rapidly expanding human populations? -- Chapter 3. A large carnivore among people and livestock: the common leopard -- Chapter 4. Recent changes in wolf habitat occupancy and feeding habits in Italy: implications for conservation and reducing conflict with humans -- Part 3. Urban wildlife conflicts are an emerging problem -- Chapter 5. ‘Good’ and ‘bad’ urban wildlife -- Chapter 6. Wildlife and traffic – an inevitable but not unsolvable problem? -- Chapter 7. The colonization of the Western Yellow-legged Gull (Larus michahellis) in an Italian city: evolution and management of the phenomenon -- Part 4. Hunting and eco-tourism: possible mechanisms for conservation and coexistence? -- Chapter 8. How hunting and wildlife conservation can coexist. Review and case studies -- Chapter 9. What do we know about wild boar in Iberia? -- Chapter 10. Travelling in a fragile world: The value of Ecotourism -- Part 5. Species extinction -- Chapter 11. Assessing presence, decline and extinction for the conservation of difficult-to-observe species -- Chapter 12. Extinct or perhaps surviving relict populations of big cats. Their controversial stories and implications for conservation -- Part 6. Zoos, Conservation, Animal Rights -- Chapter 13. Alternative facts and alternative views: Scientists, managers, and animal rights activists -- Chapter 14. Zoos and conservation in the Anthropocene: opportunities and problems -- Chapter 15. Problematic Animals in the Zoo: the issue of charismatic megafauna -- Chapter 16. Cryptic problematic species and troublesome taxonomists: A tale of the Apennine bear and the Nile white rhinoceros -- Chapter 17. Communication and wildlife conservation (grey wolf and brown bear in Italy) -- Part 7. Humans and Herpetofauna -- Chapter 18. Snakes, snakebites, and humans -- Chapter 19. Giant Snake-Human Relationships -- Chapter 20. Risk assessment model for brown treesnake introduction into the continental United States -- Chapter 21. The Asian toad (Duttaphrynus melanostictus) in Madagascar: A report of an ongoing invasion -- Index.
    Abstract: In a world where habitats are constantly changing and the impact of anthropization on the environment is increasingly intense, interactions between human and wildlife are becoming more and more complex. Some species pose problems for human activities while many others need to be helped in order to continue to exist. This book follows the first volume called 'Problematic Wildlife', edited by F.M. Angelici and published by Springer in 2016, which has had considerable success with readers and critics. The volume includes 21 chapters divided into 7 parts devoted specific topics which are approached in a multidisciplinary way. There are both review chapters and specific cases, always bearing in mind the interest for an international audience. The book can be useful both for scientists, wildlife specialists, conservationists, zoologists, ecologists, university students, nature managers, and for those who live in contact with wildlife and its problems, such as farmers, shepherds, hunters, urban planners, and staff of parks and nature reserves. Its ultimate goal is to offer scientific and pragmatic approaches to manage each categories of problematic species.
    Type of Medium: Online Resource
    Pages: XIV, 649 p. 106 illus., 78 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030423353
    URL: https://doi.org/10.1007/978-3-030-42335-3
    DOI: 10.1007/978-3-030-42335-3
    DDC: 591.568
    Language: English
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    Nanoagronomy (2020)
    Cham :Springer International Publishing :
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    Keywords: Agriculture. ; Nanotechnology. ; Botanical chemistry. ; Plant physiology. ; Plant biotechnology. ; Plants Development. ; Agriculture. ; Nanotechnology. ; Plant Biochemistry. ; Plant Physiology. ; Plant Biotechnology. ; Plant Development.
    Description / Table of Contents: 1. Nanotechnology: A breakthrough in Agronomy -- 2. Nanotechnology and Plant Tissue Culture -- 3. Nanotechnology and abiotic stresses -- 4. Myconanoparticles in agriculture -- 5. Nanotechnology in pest management -- 6. DNA nanobiotechnology and plant breeding -- 7. Nanotechnology and Plant Disease Diagnosis and Management -- 8. Nanofertilizers -- 9. Nanotechnology and waste water treatment -- 10. Applications of nano-biosensors in agriculture -- 11. Nanomaterials and agriwaste -- 12. Prospects and constraints.
    Abstract: In this age of population explosion and depleting natural resources, this book offers new techniques to produce more from agricultural crops at a lower cost. The field of agronomy addresses this issue and interacts with the fields of agriculture, botany, and economics. Nanotechnology and nanoparticles play a role in agronomy. This book joins techniques from both fields into once comprehensive volume. Students of agriculture, physics, nanotechnology, and plant sciences will benefit equally from this work.
    Type of Medium: Online Resource
    Pages: IX, 221 p. 40 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030412753
    URL: https://doi.org/10.1007/978-3-030-41275-3
    DOI: 10.1007/978-3-030-41275-3
    DDC: 630
    Language: English
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    Microbial Ecosystems in Central Andes Extreme Environments : Biofilms, Microbial Mats, Microbialites and Endoevaporites (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbial ecology. ; Biotic communities. ; Astrobiology. ; Conservation biology. ; Ecology . ; Environmental education. ; Microbial Ecology. ; Ecosystems. ; Astrobiology. ; Conservation Biology. ; Environmental and Sustainability Education.
    Description / Table of Contents: Section I - General considerations -- Chap 1 - Introduction Maria Eugenia Farias (LIMLA, Argentina) -- Chap 2 - Origin and evolution of the central Andes: deserts, salars lakes and volcanoes R.Alonso (U. Nacional de Salta, Argentina) and W. Rojas (Eramine Sudámerica S.A., Argentina) -- Chap 3 - Modern microbilies mats and endovaporite system in Andean lakes: a general approach Maria Eugenia Farias (LIMLA, Argentina) -- Section II - Preandean and andean atacam desert: life at limits -- Chap 4 - Desert polyextreme environment and lithobiontic habitats J. Wierzchos, C. Ascaso, O. Artieda and M.C. Casero (Museo Nacional de Ciencias Naturales, Spain) -- Chap 5 - Desert microbiology J. Di Ruggiero (Johns Hopkins University, USA) and M.C. Casero (Museo Nacional de Ciencias Naturales, Spain) -- Chap 6 - Desert biosignatures P. Vitek (The Czech Academy of Sciences, Czech Republic) and J. Wierzchos (Museo Nacional de Ciencias Naturales, Spain) -- Chap 7 - Microbial characterization of Andean Vega's soil C. Belfiore, M.E. Farias (LIMLA, Argentina) and M. Contreras (Centro de Ecología Aplicada, Chile) -- Section III - Life in Andean Volcanoes and Fumaroles -- Chap 8 - Limits to microbial life at the altitudinal and dry extremes for life on Earth at Llullaillaco and Socompa Volcacones S. Scmidt and P. Sowell (University of Colorado, USA) -- Chap 9 - The biogeochemistry of microorganisms in the geothermal features of El Tatio Geyser Field, Chile K.D. Myers (Columbia University, USA), A.S. Angel (University of Tennessee, USA) and P.C. Bennett (The University of Texas at Austin, USA) -- Chap 10 - The unique holoarchea dominated biofilms associated Diamante Lake inside Galan Volcanoes Microbialites N. Rascova (Aix Marseille Université, France) and M.E. Farias (LIMLA, Argentina) -- Section IV - Endoevaporites and Mats in Salars and Wetlands -- Chap 11 - Endoevaporites dominated by Arquea at Laguna Tebenquiche M.C. Rasuk (LIMLA, Argentina), Pieter V. (University of Connecticut, USA), A.B. Fernández (University of Sevilla, Spain) and M.E. Farias (LIMLA, Argentina) -- Chap 12 - Rare microbial biosphere in Salar de Huasco: hyperdiversity in polyextreme aquatic ecosystem C. Dorador, N. Miranda, V. Ávalos (Universidad de Antofagasta, Chile), V. Molina (Universidad de Playa Ancha, Chile) and M. Hengst (Universidad Católica del Norte, Chile) -- Chap 13 - Microbiome of evaporites and microbial mats in the Salar de Llamara, Atacama desert M. Rasuk and M.E. Farias (LIMLA, Argentina) -- Chap 14 - Microbial diversity in athalassohaline Argentinean salterns M.R. Mora-Ruiz and R. Rosselló-Móra (Mediterranean Institute for Advanced Studies, Spain) -- Section V - Microbialites at lakes -- Chap 15 - Physicochemical and microbiological processes in carbonate precipitation in hypersaline lakes: the laguna Negra case F.J. Gomez (Centro de Investigaciones en Ciencias de la Terra, Argentina), L.C. Kah (University of Tennessee, USA), C. Mlewski, F.J. Boidi (Centro de Investigaciones en Ciencias de la Terra, Argentina) and E. Gerard (Université Paris Diderot, France) -- Chap 16 - Microbialites Laguna Socompa V. Albarracin and M.E. Farias (LIMLA, Argentina) -- Chap 17 - Microbialites oncolites and mats at Laguna La Brava P. Visscher (University of Connecticut, USA), M. Contreras (Centro de Ecologia Aplicada, Chile) and M.E. Farias (LIMLA, Argentina) -- Chap 18 - Modern microbiolites of Pozo Bravo lake, Salas de Antofalla, Antofagasta de la Sierra, Catamarca A.I. Lencina, M.N. Soria (PROIMI, Argentina), R. Palma (Universidad de Buenos Aires, Argentina) and M.E. Farias (LIMLA, Argentina) -- Section VI - Extremolites: microbes surviving in Andean microbial ecosystems -- Chap 19 - Light sensing and mechanisms of adaptation to high solar irradiation V.H. Albarracín, M. Gorriti, L. Portero, F. Zannier (PROIMI, Argentina), W. Gärtner (Max Planck Institute, Germany) and M.E. Farias (LIMLA, Argentina) -- Chap 20 - Linear megaplasmids spreading the Andean Resistome M.F. Perez and J.R. Dib (LIMLA, Argentina) -- Chap 21 - Arsenic: Not as bad as it sounds Visscher (University of Connecticut, USA), Gallagher, Contreras (Centro de Ecologia Aplicada, Chile), Farias (Universidad Nacional de La Plata, Argentina), Philippot (Univesité Paris Diderot, France), Sancho-Tomas and Somogyi (Synchroton Soleil, France) -- Section VII - Prospecting and protecting singular ecosystems -- Chap 22 - Conservation of extremophile communities in complex ecosystems M. Contreras (Centro de Ecologia Aplicada, Chile) -- Chap 23 - Integral prospection of Andean Microbial Ecosystem Project M.E Farias (LIMLA, Argentina) -- Index -- .
    Abstract: The Central Andean Altiplane represents a unique extreme environment due to its high altitude, closed basins that modulate the salt pans and saline wetlands surrounded by deserts, as well as the considerable influence of volcanic activity. UV radiation, arsenic content, high salinity, alkalinity and low dissolved oxygen levels, together with extreme daily temperature fluctuations and oligotrophic conditions, shape an environment that resembles the early Earth and, even more, extraterrestrial conditions. By developing simple biofilms stratified microbial mats or complex microbialites, extreme microbial ecosystems, colonize and thrived in different environments like salt flats, wetlands, lakes volcano vents, geysers and deserts. This book presents our current understanding of these amazing ecosystems, providing a basis for their protection and sustainable utilization. The main audience for this book included researchers and graduate students as well as professionals working in the government, mining industry and similar activities.
    Type of Medium: Online Resource
    Pages: XXIV, 292 p. 62 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030361921
    URL: https://doi.org/10.1007/978-3-030-36192-1
    DOI: 10.1007/978-3-030-36192-1
    DDC: 579.17
    Language: English
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    Evolutionary Biology—A Transdisciplinary Approach (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Evolution (Biology). ; Microbial genetics. ; Plant genetics. ; Genetics. ; Evolutionary Biology. ; Microbial Genetics. ; Plant Genetics. ; Genetics and Genomics.
    Description / Table of Contents: Genetic and morphological differentiation of common toads in the Alps and the Apennines -- Molecular phenotypes as key intermediates in mapping genotypes to fitness -- A practical guide to orthology resources -- Protein recoding through RNA editing: detection, function, evolution -- Most successful mammals in the making: a review of the Paleocene Glires -- Continuous spectrum of lifestyles of plant-associated fungi under fluctuating environments: What genetic components determine the lifestyle transition? -- Genome evolution of asexual organisms and the paradox of sex in eukaryotes -- On the origin of life and evolution of living systems from a world of biological membranes -- Orthology: promises and challenges -- Prehistoric Stone Projectile Points and Technological Convergence -- Diversity and Evolution of RNase P -- An unusual evolutionary strategy: the origins, genetic repertoire, and implications of doubly uniparental inheritance of mitochondrial DNA in bivalves -- The evolution of the FLOWERING LOCUS T-like (FTL) genes in the goosefoot subfamily Chenopodioideae -- DDE transposon as public goods -- Evolution of milk oligosaccharides of Carnivora and Artiodactyla: significance of the ratio of oligosaccharides to lactose in milk -- Making sense of noise.
    Abstract: This book includes 16 selected contributions presented at the 23rd Evolutionary Biology Meeting, which took place in Marseille in September 2019. The annual Evolutionary Biology Meetings in Marseille serve to gather leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research. The aim of these meetings is to promote the exchange of ideas to encourage interdisciplinary collaborations. Offering an up-to-date overview of recent findings in the field of evolutionary biology, this book is an invaluable source of information for scientists, teachers and advanced students.
    Type of Medium: Online Resource
    Pages: VIII, 391 p. 85 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030572464
    URL: https://doi.org/10.1007/978-3-030-57246-4
    DOI: 10.1007/978-3-030-57246-4
    DDC: 576.8
    Language: English
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  • 47
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    A Practical Guide to Protein Engineering (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Proteins . ; Biotechnology. ; Biology Technique. ; Protein Biochemistry. ; Chemical Bioengineering. ; Biological Techniques.
    Description / Table of Contents: Literature Search -- Sequence Analysis -- Structural Analysis -- Protein Expression Hosts and Expression Plasmids -- Gene Cloning -- Protein Expression -- Assay -- Gene Mutagenesis -- High-Throughput Screening (HTS) -- Protein Variants Analysis and Characterization -- Continuing from Protein Variants -- Employability.
    Abstract: This textbook introduces readers in an accessible and engaging way to the nuts and bolts of protein expression and engineering. Various case studies illustrate each step from the early sequence searches in online databases over plasmid design and molecular cloning techniques to protein purification and characterization. Furthermore, readers are provided with practical tips to successfully pursue a career as a protein engineer. With protein engineering being a fundamental technique in almost all molecular biology labs, the book targets advanced undergraduates and graduate students working in molecular biology, biotechnology and related scientific fields.
    Type of Medium: Online Resource
    Pages: XV, 202 p. 91 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030568986
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-56898-6
    DOI: 10.1007/978-3-030-56898-6
    DDC: 572.6
    Language: English
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  • 48
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    In the Search of the Lost Pearl : Rediscovery of Southern Populations of Margaritifera margaritifera (L.) in Russia as a Model of Conservation Research (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Animal migration. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Biodiversity. ; Animal Migration.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. European pearl mussel: background information and literature review -- Chapter 3. Materials and methods -- Chapter 4. Results -- Chapter 5. Discussion -- Chapter 6. Conclusions.
    Abstract: The monograph focuses on the European freshwater pearl mussel Margaritifera margaritifera, which is an endangered bivalve species. Most of its populations in the Russian section of the Baltic Sea basin had never been studied, although they were known in the past to the pearl fishers. “Rediscovery” included search for the previously unknown populations, revealing the facts of population extinctions, analysis of negative impacts, elaboration of conservation measures, and revealing of regularities in distribution. Patterns of land use and river management were analyzed. The procedure of “rediscovery” was applied for other animal species of Northwest Russia, which are threatened on a global scale – thick-shelled mussel, Unio crassus; curlew Numenius arquata; black-tailed godwit, Limosa limosa; Northern Lapwing, Vanellus vanellus; European mink, Mustela lutreola; pond bat, Myotis dasycneme; Atlantic sturgeon, Acipenser sturio; and broad-clawed crayfish, Astacus astacus. The methods and principles of conservation studies were discussed. The obtained data were analyzed with respect to current global change of biosphere. The book will appeal to specialists dealing with conservation studies and activities such as red lists, river protection, and conservation of endangered species. Moreover, a part of the book represents an interest for biogerontology as it presents discredit of the popular concept on “negligible senescence.” The data on distribution of some animals in Russia will be interesting in terms of zoology and biogeography, as they are not yet sufficiently represented in the international editions. The book can be used as supplemental reading for courses in biological invasions, ecology and conservation, and biodiversity. The work also contains chapters on global processes (deforestation, desertification, river degradation) and can therefore also be used for general courses in environmental sciences.
    Type of Medium: Online Resource
    Pages: XI, 246 p. 88 illus., 87 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030662554
    URL: https://doi.org/10.1007/978-3-030-66255-4
    DOI: 10.1007/978-3-030-66255-4
    DDC: 577.6
    Language: English
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  • 49
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    The Brassica oleracea Genome (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Plant biotechnology. ; Plant genetics. ; Agriculture. ; Plant Biotechnology. ; Plant Genetics. ; Agriculture.
    Description / Table of Contents: Economic/Academic importance -- Background of the sequencing initiatives -- Molecular mapping and cloning of genes and QTLs -- Physical mapping of the genome -- Whole genome sequencing and assembling -- Structure and composition of centromere in Brassica genome -- Genome annotation -- Gene loss -- Alternative splicing -- Gene conversion -- Gene family differentiation in Brassica species -- Glucosinates -- R genes variations after triplication -- Structural & functional genomic resources developed -- Impact on plant breeding and crop improvement -- Data bases -- Future prospects.
    Abstract: This book presents comprehensive information on genetics, genomics and breeding in Brassica oleracea, an agriculturally important species that includes popular vegetable crops such as cabbage, cauliflower, broccoli, Brussels sprouts, kale, collard greens, savoy, kohlrabi, and gai lan. The content spans whole genome sequencing, assembly and gene annotation for this global vegetable species, along with molecular mapping and cloning of genes, physical genome mapping and analyses of the structure and composition of centromeres in the B. oleracea genome. The book also elaborates on asymmetrical genome evolution and transposable elements in the B. oleracea describes gene family differentiation in comparison to other Brassica species and structural and functional genomic resources and data bases developed for B. oleracea. Useful discussions on the impact of genome sequencing on genetic improvement in the species are also included.
    Type of Medium: Online Resource
    Pages: XXIV, 145 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030310059
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-31005-9
    DOI: 10.1007/978-3-030-31005-9
    DDC: 631.52
    Language: English
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  • 50
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    Online Resource
    Studies of Epithelial Transporters and Ion Channels : Ion Channels and Transporters of Epithelia in Health and Disease - Vol. 3 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Human physiology. ; Medicine Research. ; Biology Research. ; Proteins . ; Biological transport. ; Cell membranes. ; Human Physiology. ; Biomedical Research. ; Protein Biochemistry. ; Membrane Trafficking.
    Description / Table of Contents: 1. Na+/K+-ATPase Drives Most Asymmetric Transports and Modulates the Phenotype of Epithelial Cells -- 2. Na+-K+-2Cl- Cotransporter -- 3. Thiazide-sensitive NaCl Cotransporter -- 4. NBCe1, an Electrogenic Na+ Bicarbonate Cotransporter, in Epithelia -- 5. Na+/H+ Exchangers in Epithelia -- 6. Sugar Transport Across Epithelia -- 7. Amino Acid Transporters of Epithelia -- 8. Structure-Dynamic and Regulatory Specificities of Epithelial Na+/Ca2+ Exchangers (NCX) -- 9. Urea Transporters in Health and Disease -- 10. H,K-ATPases in Epithelia -- 11. Zinc Transporters Involved in Vectorial Zinc Transport in Intestinal Epithelial Cells -- 12. Properties, Structure and Function of the Solute Carrier 26 Family of Anion Transporters -- 13. ClC-2 Chloride Channels -- 14. The Role of the Endosomal Chloride/Proton Antiporter ClC-5 in Proximal Tubule Endocytosis and Kidney Physiology -- 15. CFTR and Cystic Fibrosis: A Need for Personalized Medicine -- 16. Molecular Physiology and Pharmacology of the Cystic Fibrosis Transmembrane Conductance Regulator -- 17. TMEM16 Proteins (Anoctamins) in Epithelia -- 18. Epithelial Sodium Channels (ENaC) -- 19. ROMK and Bartter Syndrome Type 2 -- 20. Inwardly-rectifying K+ channel 4.1 regulates renal K+ excretion in the aldosterone-sensitive distal nephron -- 21. Small-molecule Pharmacology of Epithelial Inward Rectifier Potassium Channels -- 22. KCa3.1 in Epithelia -- 23. BK Channels in Epithelia -- 24. Recent Developments in the Pharmacology of Epithelial Ca2+-Activated K+ channels -- 25. KCNE regulation of KCNQ channels -- 26. Orai Channels -- 27. Trp Channels in Renal Epithelia -- 28. P2X receptors in Epithelia -- 29. The Polycystins and Polycystic Kidney Disease -- 30. Renal Aquaporins in Health and Disease.
    Abstract: This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. The focus of this volume lies with different ion channel and transporter families. Additionally, this volume benefits from pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual epithelial ion channels and transporters from the 1st Edition, along with eleven new chapters. That makes Volume 3 an insightful contribution for physiology students, scientists and clinicians.
    Type of Medium: Online Resource
    Pages: XXI, 1244 p. 256 illus., 203 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030554545
    Series Statement: Physiology in Health and Disease,
    URL: https://doi.org/10.1007/978-3-030-55454-5
    DOI: 10.1007/978-3-030-55454-5
    DDC: 612
    Language: English
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    Essentials of Tissue and Cells Banking (2021)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Hematology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Hematology.
    Description / Table of Contents: Live Donors of Tissue -- Deceased Tissue Donors -- Banking and Use of Umbilical Cord Blood -- Ocular tissue banking -- Banking of Heart Valves -- Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Storage, Processing and Preservation -- Cryopreservation in tissue banking -- Sterilisation by Irradiation -- Screening the tissue donor for infectious agents -- Contamination in the Tissue Way -- Establishing a Quality System in a Tissue Establishment -- IT System requirements for Tissue and Cell Banking -- Ethical and Regulatory Aspects of Cell and Tissue Banking -- Human embryonic stem cell banking for clinical applications – 20 years from their isolation.
    Abstract: It has been 10 years since the first edition of ‘Essentials of Tissue Banking’ has been published. There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex. The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissue establishments.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 48 illus., 28 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030716219
    URL: https://doi.org/10.1007/978-3-030-71621-9
    DOI: 10.1007/978-3-030-71621-9
    DDC: 610.72
    Language: English
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    Pediatric Vaccines and Vaccinations : A European Textbook (2021)
    Cham :Springer International Publishing :
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    Keywords: Medical microbiology. ; Pharmacology. ; Pediatrics. ; Medical Microbiology. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Part 1 General Vaccinology -- 1 Expected and Unexpected Effects of Vaccination -- 2 How Vaccinating People Can Also Protect Others -- 3 Childhood and Adolescent Immunization Programs in Europe -- 4 Vaccine Hesitancy, Acceptance, and Demand -- 5 Adjuvants in Pediatric Vaccines -- 6 Maternal Immunization -- 7 Neonatal Immunization -- Part 2 Viral Vaccines and Vaccinations -- 8 Poliovirus Vaccines -- 9 Measles–Mumps–Rubella Vaccine -- 10 Varicella Vaccines -- 11 Rotavirus Vaccine -- 12 Hepatitis A Vaccines -- 13 Hepatitis B Vaccines -- 14 Influenza Vaccines -- 15 Human Papillomavirus Vaccines -- 16 Tick-Borne Encephalitis Vaccines -- Part 3 Bacterial Vaccines and Vaccination -- 17 Tuberculosis Vaccines -- 18 Pertussis Vaccines -- 19 Haemophilus influenzae type b (Hib) Vaccines -- 20 Pediatric Combination Vaccines -- 21 Pneumococcal Vaccines -- 22 Meningococcal Vaccines -- 23 Pediatric Vaccines for Travel Outside Europe -- Part 4 New Vaccines in Pipeline Development -- 24 GBS and CMV Vaccines in Pipeline Development -- 25 Norovirus Vaccines in Pipeline Development -- 26 RSV Vaccines and Monoclonal Antibodies in Development -- 27 COVID-19 in Children and COVID-19 Vaccines -- 28 Registration of Vaccines, Safety Follow-Up, and Pediatric Investigation Plan.
    Abstract: This second fully updated and extended edition of the textbook serves as a highly readable guide on latest developments in vaccine development and vaccination programs in infants, children and adolescents from a European perspective. The first part of the book introduces to general vaccinology, immunization programs and formulation, effects and unwanted effects of vaccines. The second and third part provide an overview on current viral and bacterial vaccines. The fourth and last part of this book discusses new vaccines in the pipeline and gives insights into safety and regulatory matters. This second edition is extended by a whole new chapter on COVID-19 vaccines. This book serves as a reference textbook in the field and helps to standardize the information on vaccines and immunization programs in the WHO European Region.
    Type of Medium: Online Resource
    Pages: XIII, 319 p. 66 illus., 63 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030771737
    URL: https://doi.org/10.1007/978-3-030-77173-7
    DOI: 10.1007/978-3-030-77173-7
    DDC: 616.9041
    Language: English
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    Population Genomics: Marine Organisms (2020)
    Cham :Springer International Publishing :
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    Keywords: Freshwater ecology. ; Marine ecology. ; Evolution (Biology). ; Biodiversity. ; Animal culture. ; Plant genetics. ; Climatology. ; Freshwater and Marine Ecology. ; Evolutionary Biology. ; Biodiversity. ; Animal Science. ; Plant Genetics. ; Climate Sciences.
    Description / Table of Contents: Part I: Introduction -- Marine Population Genomics: Challenges and Opportunities -- Part II: Marine Microbes -- Part III: Genetic Diversity, Population Structure, and Biogeography -- Population Genomics of Marine Zooplankton -- Population Genomics of Early-Splitting Lineages of Metazoans -- Population Genomics and Biogeography of the Northern Acorn Barnacle (Semibalanus balanoides) Using Pooled Sequencing Approaches -- Part IV: Seascape Genomics -- Seascape Genomics: Contextualizing Adaptive and Neutral Genomic Variation in the Ocean Environment -- Part V: Adaptation, Acclimation, and Speciation -- Clinal Adaptation in the Marine Environment -- The Population Genomics of Parallel Adaptation: Lessons from Threespine Stickleback -- Mechanisms of Adaptive Divergence and Speciation in Littorina saxatilis: Integrating Knowledge from Ecology and Genetics with New Data Emerging from Genomic Studies -- Ecological Speciation in Corals -- Environmental Epigenomics and Its Applications in Marine Organisms -- Part VI: Protection, Conservation, and Management of Marine Organisms -- Marine Invasion Genomics: Revealing Ecological and Evolutionary Consequences of Biological Invasions -- Population Genomics Applied to Fishery Management and Conservation -- Marine Conservation and Marine Protected Areas -- Index.
    Abstract: Population genomics has provided unprecedented opportunities to unravel the mysteries of marine organisms in the oceans' depths. The world's oceans, which make up 70% of our planet, encompass diverse habitats and host numerous unexplored populations and species. Population genomics studies of marine organisms are rapidly emerging and have the potential to transform our understanding of marine populations, species, and ecosystems, providing insights into how these organisms are evolving and how they respond to different stimuli and environments. This knowledge is critical for understanding the fundamental aspects of marine life, how marine organisms will respond to environmental changes, and how we can better protect and preserve marine biodiversity and resources. This book brings together leading experts in the field to address critical aspects of fundamental and applied research in marine species and share their research and insights crucial for understanding marine ecosystem diversity and function. It also discusses the challenges, opportunities and future perspectives of marine population genomics. .
    Type of Medium: Online Resource
    Pages: XVI, 456 p. 75 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030379360
    Series Statement: Population Genomics,
    URL: https://doi.org/10.1007/978-3-030-37936-0
    DOI: 10.1007/978-3-030-37936-0
    DDC: 577.6
    Language: English
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    Plant microRNAs : Shaping Development and Environmental Responses (2020)
    Cham :Springer International Publishing :
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    Keywords: Plant physiology. ; Botanical chemistry. ; Plants Development. ; Plant diseases. ; Plant Physiology. ; Plant Biochemistry. ; Plant Development. ; Plant Pathology.
    Description / Table of Contents: Studying miRNAs in plants -- Regulation of plant miRNA biogenesis -- Technologies to address plant miRNA functions -- Strategies and resources for the identification of microRNAs in non-model plants -- miRNAs in the formation of epigenetic memory in plants -- miRNAs in plant development -- miRNA regulation of fruit development -- miRNAs in plant embryogenesis -- Emerging of microRNAs as key regulators in plant secondary metabolism -- miRNAs in vascular development -- miRNAs in plant abiotic and biotic stresses -- Regulation of high-temperature stress response by small RNAs -- Role of microRNAs in plant-fungus interactions -- Plant miRNAs regulate innate immunity through diverse mechanisms.
    Abstract: This book summarizes the latest findings on the functions of microRNAs in the regulation of plant development and responses to the surrounding environment. MicroRNAs are an important class of molecules that can be found in diverse groups of organisms, including plants and animals, and the investigation of their roles is a highly dynamic and “hot” research topic. The respective chapters address four main aspects, namely: microRNA investigation and annotation, the regulatory roles of microRNAs in various developmental processes, in response to abiotic factors, and in the context of biotic stress response regulation. Systematically reviewing the most important findings in this field, the book offers an essential guide for undergraduate and graduate students, teachers, and plant science researchers. Due to the potential applications of microRNAs in crop breeding and plant protection, it also represents a valuable resource for scientists in academia and the private sector alike. .
    Type of Medium: Online Resource
    Pages: XXI, 238 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357726
    Series Statement: Concepts and Strategies in Plant Sciences,
    URL: https://doi.org/10.1007/978-3-030-35772-6
    DOI: 10.1007/978-3-030-35772-6
    DDC: 571.2
    Language: English
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    Cell Biology and Translational Medicine, Volume 7 : Stem Cells and Therapy: Emerging Approaches (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Stem cells. ; Regenerative medicine. ; Medical genetics. ; Biotechnology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Clinical Genetics. ; Chemical Bioengineering.
    Description / Table of Contents: Application of iPSC to modelling of respiratory diseases -- Gene editing in human pluripotent stem cells: recent advances for clinical therapies -- Vascular wall as source of stem cells able to differentiate into endothelial cells -- Physiological and therapeutic roles of neuropeptide Y on biological functions -- Rho signaling-directed YAP/TAZ regulation encourages 3D spheroid colony formation and boosts plasticity of Parthenogenetic Stem Cells -- Transamniotic Stem Cell Therapy -- Regenerative medicine: Injectable cell-based therapeutics and approved products -- Stem Cell Therapy for Hepatocellular Carcinoma: Future Perspectives -- Potential of tribological properties of metalnanomaterials in biomedical applications -- The impact of the low frequency of the electromagnetic field on human.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the seventh volume of a continuing series Chapter “Application of iPSC to Modelling of Respiratory Diseases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 153 p. 30 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030378455
    Series Statement: Cell Biology and Translational Medicine, 1237
    URL: https://doi.org/10.1007/978-3-030-37845-5
    DOI: 10.1007/978-3-030-37845-5
    DDC: 571.6
    Language: English
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    Advances in Plant Breeding Strategies: Vegetable Crops : Volume 10: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Agriculture. ; Botany. ; Agriculture. ; Plant Science.
    Description / Table of Contents: Preface -- Part I: Leaves -- Chapter 1. Advances in Chicory (Cichorium intybus L.) Breeding Strategies (Laila Aldahak, Khaled F. M. Salem, Salih H. F. Al-Salim, and Jameel M. Al-Khayri) -- Chapter 2. Chinese Cabbage (Brassica rapa L. var. pekinensis) Breeding: Application of Molecular Technology (Takumi Okamoto, Xiaochun Wei, Hasan Mehraj, Mohammad Rashed Hossain, Ayasha Akter, Naomi Miyaji, Yoshinobu Takada, Jong-In Park, Ryo Fujimoto, Ill-Sup Nou, and Masao Watanabe) -- Chapter 3. Breeding Advances and Prospects in Rocket Salad (Eruca vesicaria ssp. sativa Mill.) Cultivation (Pasquale Tripodi, Paula Santos Coelho, and Carla Guijarro-Real) -- Chapter 4. Spring Onion (Allium fistulosum L.) Breeding Strategies (Fatimah Kayat, Ahmed Mahmood Ibrahim, and Arifullah Mohammed) -- Chapter 5. Water Spinach (Ipomoea aquatica Forsk.) Breeding (Moumita Gangopadhyay, Anup Kumar Das, Subhendu Bandyopadyay, and Samanwita Das) -- Chapter 6. Watercress (Nasturtium officinale R. Br.) Breeding (Mohammadreza Hassandokht, Sajad Jafari, and Raheleh Ebrahimi) -- Part II: Flowerheads and Green Pods -- Chapter 7. Advances in Cauliflower (Brassica oleracea var. botrytis L.) Breeding, with Emphasis on India (Pritam Kalia and Shrawan Singh) -- Chapter 8. Globe Artichoke (Cynara cardunculus var. scolymus L.) Breeding (Fernando López-Anido and Eugenia Martin) -- Chapter 9. Breeding Strategies of Garden Pea (Pisum sativum L.) (Amal M.E. Abdel Hamid and Khaled F.M. Salem) -- Chapter 10. Genetic Improvement of Yardlong Bean (Vigna unguiculata (L.) Walp. ssp. sesquipedalis (L.) Verdc.) (Pidigam Saidaiah, Thuraga Vishnukiran, Someswar Rao Pandravada, Natarajan Sivaraj, Adimulam Srivani, Amarapalli Geetha, Nimmarajula Srinivas, and Venkateswaran Kamala) -- Part III: Mushrooms -- Chapter 11. Enoki Mushroom (Flammulina velutipes (Curtis) Singer) Breeding (Ved P. Sharma, Anupam Barh, Rakesh Kumar Bairwa, Sudheer K. Annepu, Babita Kumari and Shwet Kamal) -- Chapter 12. Shiitake Mushroom (Lentinula edodes (Berk.) Sing.) Breeding in China (Quanju Xiang, Bilal Adil, Qiang Chen, Yunfu Gu, Xianfu Zeng, and Xinzhu Li) -- Part IV: Truffles -- Chapter 13. Desert Truffles (Terfezia spp.) Breeding (Asunción Morte, Francisco Arenas, José E. Marqués-Gálvez, Alberto Andrino, Ángel L. Guarnizo, Almudena Gutiérrez, Luis Miguel Berná, Manuela Pérez-Gilabert, Antonio Rodríguez, and Alfonso Navarro-Ródenas) -- Chapter 14. Enhancing White Truffle (Tuber magnatum Picco and T. borchii Vittad.) Cultivation through Biotechnology Innovation (Alessandra Zambonelli, Mirco Iotti, Federico Puliga, and Ian R. Hall).
    Abstract: Plant breeders and geneticists are under constant pressure to sustain and expand food production by using innovative breeding strategies and introducing minor crops, which are well adapted to marginal lands, provide a source of nutrition, and have abiotic and biotic stress tolerance, to feed an ever-increasing human population. The basic concept of this book is to examine the use of innovative methods, augmenting traditional plant breeding, towards the improvement and development of new crop varieties, under the increasingly limiting environmental and cultivation factors, to achieve sustainable agricultural production and enhanced food security. Three volumes of the book series Advances in Plant Breeding Strategies were published in 2015, 2016 and 2018, respectively: Volume 1. Breeding, Biotechnology and Molecular Tools; Volume 2. Agronomic, Abiotic and Biotic Stress Traits and Volume 3. Fruits. In 2019, the following four volumes were published: Volume 4. Nut and Beverage Crops, Volume 5. Cereals, Volume 6. Industrial and Food Crops and Volume 7. Legumes. Recent volumes published in 2021 include: Volume 8. Vegetable Crops: Bulbs, Roots and Tubers, Volume 9. Vegetable Crops: Fruits and Young Shoots and Volume 10. Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles. This Volume 10, subtitled Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles, consists of 14 chapters focusing on advances in breeding strategies using both traditional and modern approaches for the improvement of individual vegetable crops. Chapters are arranged in 4 parts according to the edible vegetable parts. Part I: Leaves - Chicory, Chinese cabbage, Rocket salad, Spring onion, Water spinach and Watercress; Pat II: Flowerheads and Green Pods - Cauliflower, Globe artichoke, Garden pea and Yardlong bean; Part III: Mushrooms - Enoki mushroom and Shiitake mushroom; Part IV: Truffles - Desert truffles and White truffle. Each chapter comprehensively reviews the contemporary literature on the subject and reflects the experiences of the authors. Chapters are written by internationally-reputable scientists and subjected to a review process to assure quality presentation and scientific accuracy. Each chapter begins with an introduction covering related backgrounds and provides in-depth discussion of the subject supported with high-quality color photos, illustrations and relevant data. The chapter concludes with recommendations for future research directions, a comprehensive list of pertinent references to facilitate further reading, and appendixes of genetic resources and concerned research institutes. This book series is a valuable resource for advanced students, researchers, scientists, commercial producers and seed companies as well as consultants and policymakers interested in agriculture, particularly in modern breeding technologies.
    Type of Medium: Online Resource
    Pages: XVII, 540 p. 98 illus., 76 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030669690
    URL: https://doi.org/10.1007/978-3-030-66969-0
    DOI: 10.1007/978-3-030-66969-0
    DDC: 630
    Language: English
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    Plant Performance Under Environmental Stress : Hormones, Biostimulants and Sustainable Plant Growth Management (2021)
    Cham :Springer International Publishing :
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    Keywords: Plant anatomy. ; Stress (Physiology). ; Plants. ; Plant physiology. ; Plant ecology. ; Plants Development. ; Agriculture. ; Plant Anatomy and Morphology. ; Plant Stress Responses. ; Plant Physiology. ; Plant Ecology. ; Plant Development. ; Agriculture.
    Description / Table of Contents: Crosstalk between autophagy and hormones for abiotic stress tolerance in plants -- Abscisic acid and plant response under adverse environmental conditions -- Auxins and plant response to adverse environmental conditions -- Jasmonic acid for sustainable plant growth and production under adverse environmental conditions -- Salicylic acid for vigorous plant growth and enhanced yield under harsh environment -- Strigolactones for sustainable plant growth and production under adverse environmental conditions -- Polyamines for sustainable plant growth and production under adverse environmental conditions -- Plant performance and defensive role of proline under environmental stress -- Plant performance and defensive role of β-amino butyric acid under environmental stress -- Plant performance and defensive role of γ-gamma amino butyric acid under environmental stress -- Nitric oxide: A key modulator of plant responses under environmental stress -- Functions of hydrogen sulfide in plant regulation and response to abiotic stress -- Silicon and plant responses under adverse environmental conditions -- Nanofertilizers as tools for plant nutrition and plant biostimulation under adverse environment -- Biostimulants and plant response under adverse environmental conditions: a functional interplay -- Biofertilizers-mediated sustainable plant growth and production under adverse environmental conditions -- Seed priming: A cost-effective strategy to impart abiotic stress tolerance -- Significance of cyanobacteria in soil-plant system and for ecological resilience -- Phytomicrobiome community: An agrarian perspective -- Adverse environment and pest management for sustainable plant production -- Eco-friendly approaches of using weeds for sustainable plant growth and production.
    Abstract: Global climate change is bound to create a number of abiotic and biotic stresses in the environment, which would affect the overall growth and productivity of plants. Like other living beings, plants have the ability to protect themselves by evolving various mechanisms against stresses, despite being sessile in nature. They manage to withstand extremes of temperature, drought, flooding, salinity, heavy metals, atmospheric pollution, toxic chemicals and a variety of living organisms, especially viruses, bacteria, fungi, nematodes, insects and arachnids and weeds. Incidence of abiotic stresses may alter the plant-pest interactions by enhancing susceptibility of plants to pathogenic organisms. These interactions often change plant response to abiotic stresses. Plant growth regulators modulate plant responses to biotic and abiotic stresses, and regulate their growth and developmental cascades. A number of physiological and molecular processes that act together in a complex regulatory network, further manage these responses. Crosstalk between autophagy and hormones also occurs to develop tolerance in plants towards multiple abiotic stresses. Similarly, biostimulants, in combination with correct agronomic practices, have shown beneficial effects on plant metabolism due to the hormonal activity that stimulates different metabolic pathways. At the same time, they reduce the use of agrochemicals and impart tolerance to biotic and abiotic stress. Further, the use of bio- and nano-fertilizers seem to hold promise to improve the nutrient use efficiency and hence the plant yield under stressful environments. It has also been shown that the seed priming agents impart stress tolerance. Additionally, tolerance or resistance to stress may also be induced by using specific chemical compounds such as polyamines, proline, glycine betaine, hydrogen sulfide, silicon, β-aminobutyric acid, γ-aminobutyric acid and so on. This book discusses the advances in plant performance under stressful conditions. It should be very useful to graduate students, researchers, and scientists in the fields of botanical science, crop science, agriculture, horticulture, ecological and environmental science.
    Type of Medium: Online Resource
    Pages: XIV, 606 p. 54 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030785215
    URL: https://doi.org/10.1007/978-3-030-78521-5
    DOI: 10.1007/978-3-030-78521-5
    DDC: 571.32
    Language: English
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    Tumor Microenvironment : Signaling Pathways – Part B (2021)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Biophysics. ; Cell interaction. ; Cytology. ; Cancer Microenvironment. ; Mechanobiological Cell Signaling. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 191 p. 31 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030471897
    Series Statement: Advances in Experimental Medicine and Biology, 1270
    URL: https://doi.org/10.1007/978-3-030-47189-7
    DOI: 10.1007/978-3-030-47189-7
    DDC: 571.978
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    Mechanisms of Gene Regulation: How Science Works (2020)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Biochemistry. ; Genetics. ; Biomedical Research. ; Biochemistry. ; Genetics and Genomics.
    Description / Table of Contents: Central dogma of molecular biology -- Impact of chromatin structure -- Epigenetics enables gene expression -- Gene regulation in the context of nuclear architecture -- Core promoter -- TATA box and other core promoter elements -- Genome-wide core promoter identification -- TFIID and Mediator as paradigms of multi-protein complexes -- Site-specific transcription factors and their domains -- Classification of transcription factors -- Activation of transcription factors -- Programing cellular differentiation by transcription factors -- Inflammatory signaling via NF-KB -- Sensing cellular stress via p53 -- The nuclear receptor superfamily -- Molecular interactions of nuclear receptors -- Physiological role of nuclear receptors -- Next-generation sequencing -- Gene regulation in the context of Big Biology -- Exploring genome-wide transcription factor binding -- Integrating epigenome-wide datasets -- Cytosines and their methylation -- Histone modifications -- Gene regulation via chromatin modifiers -- Sensing energy metabolism via chromatin modifiers -- Epigenetics and chromatin -- Genome-wide understanding of epigenetics -- CTCF and genetic imprinting -- Epigenetics in health and disease -- Nucleosome positioning at promoters -- Chromatin remodeling -- Transcriptional dynamics in the presence of chromatin -- Organization of the nucleus -- Non-coding RNAs -- miRNAs and their regulatory potential -- Long ncRNAs -- Enhancer RNAs.
    Abstract: This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. Th is pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation.
    Type of Medium: Online Resource
    Pages: XVI, 149 p. 71 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030523213
    URL: https://doi.org/10.1007/978-3-030-52321-3
    DOI: 10.1007/978-3-030-52321-3
    DDC: 610.72
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    Essential Current Concepts in Stem Cell Biology (2020)
    Cham :Springer International Publishing :
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    Keywords: Biotechnology. ; Stem cells. ; Hematology. ; Regenerative medicine. ; Biotechnology. ; Stem Cell Biology. ; Hematology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Hematopoietic Stem Cells -- Mesenchymal Stem Cells -- Cord Blood Stem Cells -- Neural Stem Cells and Their Niche -- Skeletal Muscle Stem Cells -- Heart Muscle Tissue Engineering -- Induced Pluripotent Stem Cells -- Epigenetics of Somatic Cell Reprogramming -- Human Pluripotent Stem Cells and Neural Regeneration -- Dopaminergic Neuron-Related Stem Cells -- Liver Disease Modelling -- Organoids in Developmental Biology Research and Application -- Extracellular Vesicles -- Ethics in Stem Cell Applications.
    Abstract: This textbook describes the biology of different stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal cord blood, neural and muscle stem cells and also covers induced pluripotent stem cells and their applications. Further, it includes chapters on organoids, stem-cell based disease modelling, extracellular vesicles and one chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on lectures of the international master program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and participation of collaborating professors from Tongji University Shanghai, the book is a valuable source for students, postdocs and researchers, who would like to have introductory chapters on stem cell biology. It also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.
    Type of Medium: Online Resource
    Pages: XIV, 242 p. 37 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339234
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-33923-4
    DOI: 10.1007/978-3-030-33923-4
    DDC: 660.6
    Language: English
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    Amino Acids in Nutrition and Health : Amino acids in systems function and health (2020)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Preface -- Amino acids in intestinal physiology and health -- Amino acid metabolism in the liver: nutritional and physiological significance -- Amino acids in circulatory function and health -- Epithelial dysfunction in lung diseases: effects of amino acids and potential mechanisms -- Amino acid metabolism in the kidneys: nutritional and physiological significance -- Amino acids in health and endocrine function -- Amino Acids in Reproductive Nutrition and Health -- Impacts of amino acids on the intestinal defensive system -- Maternal nutrient restriction and skeletal muscle development: Consequences for postnatal health -- Metabolism of amino acids in the brain and their roles in regulating food intake -- Metabolism and functions of amino acids in the skin -- Metabolism and functions of amino acids in sense organs. .
    Abstract: This edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in all the systems of humans and other animals (including livestock, poultry, companion animals, and fish). It enables readers to understand the crucial roles of amino acids and their metabolites in the health and diseases of the circulatory, digestive, endocrine, immune, muscular, nervous, reproductive, respiratory, skeletal, and urinary systems, as well as the sense organs (eyes, ears, nose, skin, and tongue). Readers will learn that amino acids are not only the building blocks of protein, but are also signalling molecules, as well as regulators of gene expression, metabolic processes and developmental changes in the body. This knowledge will guide nutritional practices to improve the growth, development and health of humans and other animals, as well as prevent and treat chronic (e.g., obesity, diabetes, and cardiovascular disorders) and infectious (e.g., bacterial, fungal, parasite, and viral) diseases. Editor of this volume is an internationally recognized expert in nutritional biochemistry. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals as well as undergraduate and graduate students in animal science, biochemistry, biomedical engineering, biology, human medicine, food science, kinesiology, nursing, nutrition, pharmacology, physiology, toxicology, veterinary medicine, and other related disciplines. In addition, all chapters provide general and specific references to amino acids in systems health for researchers and practitioners in biomedicine, animal and plant agriculture, and aquaculture, and for government policy makers.
    Type of Medium: Online Resource
    Pages: VI, 220 p. 36 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030453282
    Series Statement: Advances in Experimental Medicine and Biology, 1265
    URL: https://doi.org/10.1007/978-3-030-45328-2
    DOI: 10.1007/978-3-030-45328-2
    DDC: 571.96
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    Coenzyme Q in Aging (2020)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Biochemistry. ; Physiology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Biochemistry. ; Physiology.
    Description / Table of Contents: Preface -- Part 1 Basics on coenzyme Q -- Introduction. The current coenzyme Q science and knowledge -- Molecular structure, biosynthesis, and distribution of coenzyme Q -- Coenzyme Q function in mitochondria -- Extramitochondrial coenzyme Q10 in aging -- Regulation of the synthesis of Coenzyme Q10 -- Part 2 Coenzyme Q in aging studies -- Coenzyme Q and aging in C. elegans -- Coenzyme Q and aging in the fruit fly Drosophila melanogaster -- The aging process and coenzyme Q: clk-1 mouse models -- Reduced coenzyme Q10 decelerates senescence and age-related hearing loss in senescence-accelerated mice by activating mitochondrial functions -- Part 3 Age-related diseases and coenzyme Q -- Coenzyme Q, mtDNA and mitochondrial dysfunction during aging -- Coenzyme Q10 and metabolic syndrome -- Coenzyme Q and age-related neurodegenerative disorders: Parkinson and Alzheimer diseases -- Immunosenescence and CoQ10 -- Coenzyme Q10 in fertility and reproduction -- Part 4 Prolongevity effectors and Coenzyme Q -- Calorie restriction, longevity and coenzyme Q -- Age dependent changes of coenzyme Q levels and its induction in experimental systems -- Effects of coenzyme Q10 supplementation on elderly people -- Index.
    Abstract: This book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q10 and the process of aging in living organisms. CoQ10 is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ10 is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging. The book is organized in four sections. The first offers an overview of the function of CoQ10, highlighting the two main functions of CoQ10 in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. The second section covers research on Coenzyme 10. Topics include studies involving invertebrate models, mammal studies and the influence of CoQ on longevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. Section three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. The final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ10 levels by induction of synthesis or by supplementation. Coenzyme Q in Aging benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process.
    Type of Medium: Online Resource
    Pages: XII, 369 p. 50 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030456429
    URL: https://doi.org/10.1007/978-3-030-45642-9
    DOI: 10.1007/978-3-030-45642-9
    DDC: 610.72
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    Agriculturally Important Fungi for Sustainable Agriculture : Volume 2: Functional Annotation for Crop Protection (2020)
    Cham :Springer International Publishing :
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    Keywords: Fungi. ; Mycology. ; Microbiology. ; Agriculture. ; Plants Evolution. ; Plant biotechnology. ; Plants Development. ; Fungi. ; Agriculture. ; Plant Evolution. ; Plant Biotechnology. ; Plant Development.
    Description / Table of Contents: Preface -- Introduction to Agriculturally Important Fungi for Crop Protection -- Role of Fungi in Adaptation of Agriculture Crops to Abiotic Stresses -- Arbuscualr Mycorrhizae Associations and Role in Mitigation of Drought Stress in Plants -- Fungal Mediated Alleviation of Cold Stress for Growth and Yield of Cereal Crops -- Soil Salinity and their Alleviation Using Plant Growth Promoting Fungi -- Phytohormones Producing Fungal Communities -- Fungal Secondary Metabolites and Bioactive Compounds for Plant Defence -- Fungal Endophytes -- Aspergillus Mycotoxins -- Trichoderma -- Piriformospora indica -- Bioresources for Control of Plant Parasitic Nematodes -- Global Scenario of Advance Fungal Research in Biocontrol and Crop Protection -- Index -- .
    Abstract: Microbes are ubiquitous in nature. Among microbes, fungal communities play an important role in agriculture, the environment, and medicine. Vast fungal diversity has been found in plant systems. The fungi associated with any plant system are in the form of epiphytic, endophytic, and rhizospheric fungi. These associated fungi play important roles in plant growth, crop yield, and soil health. The rhizospheric fungi present in rhizospheric zones have a sufficient amount of nutrients released by plant root systems in the form of root exudates for growth, development, and activities of microbes. Endophytic fungi enter in host plants mainly through wounds that naturally occur as a result of plant growth, or develop through root hairs and at epidermal conjunctions. The phyllospheric fungi may survive or proliferate on leaves, depending on the extent of influences of material in leaf diffuseness or exudates. The diverse group of fungal communities is a key component of soil-plant systems, where they are engaged in an intense network of interactions in the rhizospheric, endophytic, and phyllospheric areas, and they have emerged as an important and promising tool for sustainable agriculture. These fungal communities help to promote plant growth directly or indirectly by mechanisms for plant growth-promoting (PGP) attributes. These PGP fungi can be used as biofertilizers, bioinoculants, and biocontrol agents in place of chemical fertilizers and pesticides in an environmentally and eco-friendly manner. This book covers the current knowledge of plant-associated fungi and their potential biotechnological applications in agriculture and allied sectors. This book should be useful to scientists, researchers, and students of microbiology, biotechnology, agriculture, molecular biology, environmental biology, and related subjects.
    Type of Medium: Online Resource
    Pages: XVIII, 370 p. 40 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030484743
    Series Statement: Fungal Biology,
    URL: https://doi.org/10.1007/978-3-030-48474-3
    DOI: 10.1007/978-3-030-48474-3
    DDC: 579.5
    Language: English
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    Cavernomas of the CNS : Basic Science to Clinical Practice (2020)
    Cham :Springer International Publishing :
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    Keywords: Nervous system Surgery. ; Blood-vessels Surgery. ; Neurology . ; Neurosurgery. ; Vascular Surgery. ; Neurology.
    Description / Table of Contents: Brief History of Cavernous Malformations -- Definition and structure of cerebral cavernous malformations -- Molecular Biology of CCM -- Presentation -- Neuroimaging of Cerebral Cavernous Malformations -- Natural history of cavernous malformations -- Hemispherical Cavernomas in non-eloquent and eloquent areas -- Cavernoma-Related Epilepsy -- Surgery of deep-seated cavernous malformations -- Surgery of brainstem and cerebellar cavernous malformations -- Stereotactic Radiosurgery of Cavernous Malformations -- Cavernomas in children -- Cavernomas During Pregnancy -- Spinal cavernous malformations -- Intraorbital cavernous malformations.
    Abstract: This book presents a complete up-to date description of cavernoma disease together with its known biology, genetics and variable clinical presentation. It facilitates improved decision-making on surgical intervention by presenting different cases, highlighting the particular features of lesions such as anatomical location, eloquences of adjacent brain and type of presentation that are important when making decisions. In addition, the reader is brought up to speed with developments in the neuroimaging and active treatment techniques, especially surgical resection and radiosurgery. Finally, the natural history of the disease is taken into account and compared to the possible benefits of surgical treatment. Cavernomas of the CNS: Basic Science to Clinical Practice provides a comprehensive overview from the fundamentals of this condition, to special patient groups such as children and pregnant women. Therefore, it is an indispensable resource for neurovascular surgeons, neurosurgical residents and neurologists.
    Type of Medium: Online Resource
    Pages: VIII, 245 p. 124 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030494063
    URL: https://doi.org/10.1007/978-3-030-49406-3
    DOI: 10.1007/978-3-030-49406-3
    DDC: 617.48
    Language: English
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    Cancer Biology: How Science Works (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Genetics. ; Molecular biology. ; Cancer Biology. ; Genetics and Genomics. ; Molecular Biology.
    Description / Table of Contents: 1. Introduction to cancer -- 2. Oncogenes, signal transduction and the hallmarks of cancer -- 3. Tumor suppressor genes and cell fate control -- 4. Multi-step tumorigenesis and genome instability -- 5. Cancer genomics -- 6. Cancer epigenomics -- 7. Aging and cancer -- 8. Tumor microenvironment -- 9. Metastasis and cachexia -- 10. Cancer immunity -- 11. Architecture of cancer therapies.
    Abstract: Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
    Type of Medium: Online Resource
    Pages: XVII, 167 p. 72 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030756994
    URL: https://doi.org/10.1007/978-3-030-75699-4
    DOI: 10.1007/978-3-030-75699-4
    DDC: 571.978
    Language: English
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    Triatominae - The Biology of Chagas Disease Vectors (2021)
    Cham :Springer International Publishing :
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    Keywords: Invertebrates. ; Parasitology. ; Veterinary microbiology. ; Invertebrate Zoology. ; Parasitology. ; Veterinary Microbiology.
    Description / Table of Contents: 1.Origin and evolution of Triatominae -- 2. Taxonomy -- 3. Speciation Processes in Triatominae -- 4. Chromosome structure and evolution of Triatominae: A review -- 5. Embryonic development of the kissing bug Rhodnius prolixus -- 6. Anatomy of the nervous system of triatomines -- 7. Biogenic monoamines in the control of triatomine physiology with emphasis on Rhodnius prolixus -- 8. Structure and physiology of the neuropeptidergic system of triatomines -- 9. Sensory biology of triatomines -- 10. The behaviour of kissing-bugs -- 11. Features of interaction between triatomines and vertebrates based on bug feeding parameters -- 12. Blood Digestion in Triatomine Insects -- 13. The physiology of sperm transfer and egg production in vectors of Chagas disease with particular reference to Rhodnius prolixus -- 14. The Immune System of Triatomines -- 15. Interaction of triatomines with their bacterial microbiota and trypanosomes -- 16. The ecology and natural history of wild Triatominae in the Americas -- 17. Eco-epidemiology of vector-borne transmission of Trypanosoma cruzi in domestic habitats -- 18. Chagas Disease Vector Control -- 19. Insecticide resistance in triatomines -- 20. Perspectives in triatomine biology studies: “Omics”- based approaches.
    Abstract: This book aims to present updated knowledge on various aspects of the natural history, biology, and impact of triatomines to all interested readers. Each chapter will be written by authorities in the respective field, covering topics such as behavior, neurophysiology, immunology, ecology, and evolution. The contents will consider scientific, as well as innovative perspectives, on the problems related to the role of triatomine bugs as parasite vectors affecting millions in the Latin American region.
    Type of Medium: Online Resource
    Pages: XXX, 620 p. 62 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030645489
    Series Statement: Entomology in Focus, 5
    URL: https://doi.org/10.1007/978-3-030-64548-9
    DOI: 10.1007/978-3-030-64548-9
    DDC: 592
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    Intraoperative Mapping of Cognitive Networks : Which Tasks for Which Locations (2021)
    Cham :Springer International Publishing :
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    Keywords: Nervous system Surgery. ; Neuropsychology. ; Neurology . ; Neurosurgery. ; Neuropsychology. ; Neurology.
    Description / Table of Contents: Foreword -- Preface -- Part I: Sensorimotor and visuo-spatial functions -- 1. Motor control -- 2. Vision -- 3. FEF -- 4. Spatial cognition -- Part II: Language functions -- 5. Lexical access -- 6. Spontaneous speech -- 7. Reading -- 8. Writing -- 9. Repeating -- 10. Syntactic abilities -- 11. Verbs versus nouns naming -- 12. Verbal short-term memory -- 13. Proper names retrieval -- 14. Bilingual patients -- Part III: Higher-order functions -- 15. From verbal to non-verbal semantics -- 16. Inhibition -- 17. Set-shifting -- 18. Social cognition -- 19. Multitask mapping -- Part IV: Prospects -- 20. Creativity -- 21. Psychiatric and behavorial traits -- 22. Awake surgery in patients with poor abilities of verbal communication -- 23. Can we map inner speech? -- 24. Beyond tasks: when experience shapes intuition.
    Abstract: This book aims to give the state-of-the-art of intraoperative brain function mapping for resection of brain tumors in awake conditions, and to become a reference for acquiring the fundamental expertise necessary to select the right intraoperative task at the right time of the surgery. The chapters, all focused on a specific brain function, are divided in 4 parts: sensori-motor and visuo-spatial functions, language functions, higher-order functions, and prospects. Each chapter follows the same outline, including a brief review of the current knowledge about the networks sustaining the function in healthy subjects, the description of the intraoperative tasks designed to monitor the function, a review of the literature describing the deficits in that function after surgery, and a critical appraisal of the benefit provided by intraoperative mapping of that function.
    Type of Medium: Online Resource
    Pages: XIV, 421 p. 93 illus., 90 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030750718
    URL: https://doi.org/10.1007/978-3-030-75071-8
    DOI: 10.1007/978-3-030-75071-8
    DDC: 617.48
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    Time Expression and Named Entity Recognition (2021)
    Cham :Springer International Publishing :
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    Keywords: Artificial intelligence. ; Artificial Intelligence.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Literature Review -- Chapter 3. Data Analysis -- Chapter 4. SynTime: Token Types and Heuristic Rules -- 5. TOMN: Constituent-based Tagging Scheme -- Chapter 6. UGTO: Uncommon Words and Proper Nouns -- Chapter 7. Conclusion and Future Work.
    Abstract: This book presents a synthetic analysis about the characteristics of time expressions and named entities, and some proposed methods for leveraging these characteristics to recognize time expressions and named entities from unstructured text. For modeling these two kinds of entities, the authors propose a rule-based method that introduces an abstracted layer between the specific words and the rules, and two learning-based methods that define a new type of tagging scheme based on the constituents of the entities, different from conventional position-based tagging schemes that cause the problem of inconsistent tag assignment. The authors also find that the length-frequency of entities follows a family of power-law distributions. This finding opens a door, complementary to the rank-frequency of words, to understand our communicative system in terms of language use.
    Type of Medium: Online Resource
    Pages: XIX, 96 p. 17 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030789619
    Series Statement: Socio-Affective Computing, 10
    URL: https://doi.org/10.1007/978-3-030-78961-9
    DOI: 10.1007/978-3-030-78961-9
    DDC: 006.3
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    Advances in Plant Breeding Strategies: Vegetable Crops : Volume 8: Bulbs, Roots and Tubers (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Agriculture. ; Botany. ; Agriculture. ; Plant Science.
    Description / Table of Contents: Preface -- Part I: Bulbs -- Chapter 1. Traditional and Novel Approaches in Garlic (Allium sativum L.) Breeding (Einat Shemesh-Mayer and Rina Kamenetsky Goldstein) -- Chapter 2. Genetic Improvement of Leek (Allium ampeloprasum L.) (Fevziye Celebi-Toprak and Ali Ramazan Alan) -- Chapter 3. Shallot (Allium cepa L. Aggregatum group) Breeding (Haim D. Rabinowitch) -- Part II: Roots -- Chapter 4. Molecular Breeding Strategies of Beetroot (Beta vulgaris ssp. vulgaris var. conditiva Alefeld) (Farrag F.B. Abu-Ellail, Khaled F.M. Salem, Maysoun M. Saleh, Lina M. Alnaddaf, and Jameel M. Al-Khayri) -- Chapter 5. Carrot (Daucus carota L.) Breeding (Philipp W. Simon) -- Chapter 6. Parsnip (Pastinaca sativa L.) Breeding for the Future (Lauren H.K. Chappell and Adrian J. Dunford) -- Chapter 7. Radish (Raphanus sativus L.): Breeding for Higher Yield, Better Quality and Wider Adaptability (Binod Kumar Singh) -- Chapter 8. Sugar Beet (Beta vulgaris ssp. vulgaris L.) Improvement with Next-generation Breeding Technology (Chiara De Lucchi, Enrico Biancardi, George Skaracis, Marco De Biaggi, Ourania Pavli, Samathmika Ravi, Claudia Chiodi, Chiara Broccanello, and Piergiorgio Stevanato) -- Chapter 9. Turnip (Brassica rapa var. rapa L.) Breeding (Hesham S. Abdel-Razzak) -- Part III: Tubers -- Chapter 10. Recent Advances in Potato (Solanum tuberosum L.) Breeding (Emre Aksoy, Ufuk Demirel, Allahbakhsh Joiya, Muhammad Abu Bakar Zia, Muhammad Naeem Sattar, Faisal Saeed, Sevgi Çalışkan, and Mehmet Emin Çalışkan) -- Chapter 11. Application of Genome Editing Tools to Accelerate Potato (Solanum tuberosum L.) Breeding (Zafar Iqbal and Muhammad Naeem Sattar) -- Chapter 12. Sweet potato (Ipomoea batatas L.) Breeding (Jolien Swanckaert, Dorcus Gemenet, Noelle L. Anglin, and Wolfgang Grüneberg).
    Abstract: Plant breeders and geneticists are under constant pressure to sustain and expand food production by using innovative breeding strategies and introducing minor crops, which are well adapted to marginal lands, provide a source of nutrition, and have abiotic and biotic stress tolerance, to feed an ever-increasing human population. The basic concept of this book is to examine the use of innovative methods, augmenting traditional plant breeding, towards the improvement and development of new crop varieties, under the increasingly limiting environmental and cultivation factors, to achieve sustainable agricultural production and enhanced food security. Three volumes of the book series Advances in Plant Breeding Strategies were published in 2015, 2016 and 2018, respectively: Volume 1. Breeding, Biotechnology and Molecular Tools; Volume 2. Agronomic, Abiotic and Biotic Stress Traits and Volume 3. Fruits. In 2019, the following four volumes were published: Volume 4. Nut and Beverage Crops, Volume 5. Cereals, Volume 6. Industrial and Food Crops and Volume 7. Legumes. Recent volumes published in 2021 include: Volume 8. Vegetable Crops: Bulbs, Roots and Tubers, Volume 9. Vegetable Crops: Fruits and Young Shoots and Volume 10. Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles. This Volume 8, subtitled Vegetable Crops: Bulbs, Roots and Tubers, consists of 12 chapters focusing on advances in breeding strategies using both traditional and modern approaches for the improvement of individual vegetable crops. Chapters are arranged in 3 parts according to the edible vegetable parts. Part I: Bulbs - Garlic, Leek and Shallot; Part II: Roots - Beetroot, Carrot, Parsnip, Radish, Sugar beet and Turnip, Part III: Tubers - Potato and Sweet potato. Each chapter comprehensively reviews the contemporary literature on the subject and reflects the experiences of the authors. Chapters are written by internationally-reputable scientists and subjected to a review process to assure quality presentation and scientific accuracy. Each chapter begins with an introduction covering related backgrounds and provides in-depth discussion of the subject supported with high-quality color photos, illustrations and relevant data. The chapter concludes with recommendations for future research directions, a comprehensive list of pertinent references to facilitate further reading, and appendixes of genetic resources and concerned research institutes. This book series is a valuable resource for advanced students, researchers, scientists, commercial producers and seed companies as well as consultants and policymakers interested in agriculture, particularly in modern breeding technologies.
    Type of Medium: Online Resource
    Pages: XV, 554 p. 105 illus., 86 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030669652
    URL: https://doi.org/10.1007/978-3-030-66965-2
    DOI: 10.1007/978-3-030-66965-2
    DDC: 630
    Language: English
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    Modern Approaches to Augmentation of Brain Function (2021)
    Cham :Springer International Publishing :
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    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. Using electrical stimulation to explore and augment the functions of parietal-frontal cortical networks in primates -- 2. Multi-system benefits of epidural stimulation following spinal cord injury. 3. Neurostimulator for hippocampal memory prosthesis -- 4. Modern approaches to augmenting the brain functions -- 5. Brain machine interfaces within a critical perspective -- 6. An implantable wireless device for ECoG and cortical stimulation -- 7. BCI Performance improvement by special low jitter quasi-steady State VEP paradigm -- 8. Communication with Brain-Computer Interfaces in Medical Decision-Making -- 9. Neuroprotection and neurocognitive augmentation by photobiomodulation -- 10. Avoiding partial sleep - the way for augmentation of brain function -- 11. Augmentation of brain functions by nanotechnology -- 12. The impact of ageing and age-related comorbidities on stroke outcome in animal models and humans -- 13. Diagnostic markers of sub-clinical depression based on functional connectivity -- 14. Transcranial magnetic stimulation in autism spectrum disorders: modulating brainwave abnormalities and behaviors -- 15. Neurofeedback training with concurrent psychophysiological monitoring in children with autism spectrum disorder with comorbid attention deficit/hyperactivity disorder -- 16. Augmentation through interconnection: brain-nets and telemedicine -- 17. Cognitive augmentation via a brain/cloud interface -- 18. Augmentation of neuro-marketing by neural technology -- 19. Augmentation of nutrition by nanotechnology -- 20. Neural spintronics: noninvasive augmentation of brain functions -- 21. Does the power to suppress an action make us free? -- 22. Deep brain stimulation for Parkinson’s disease-future directions for enhancing motor function -- 23. Neuromodulation for gait -- 24. Augmentation and rehabilitation with active orthotic devices -- 25. Effects of rTMS on behavioral and electrocortical measures of error monitoring and correction function in children with autism spectrum disorder -- 26. Affective Virtual Reality Gaming for Autism -- 27. A machine learning approach to automatic phobia therapy with virtual reality -- 28. Vision augmentation by pharmacological enhancement of the visual experience -- 29. Cognitive enhancing substances and the developing brain: risks and benefits -- 30. Pharmacological approaches in the augmentation and recovery of brain function.
    Abstract: This book covers recent advances in the neural technology that produces enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the behavior and mind. Augmentation of brain function is achieved using brain implants for recordings, stimulation and drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. Existing methods of brain augmentation are evaluated, and new approaches are introduced. Brain circuitry and neuronal mechanisms that are candidates for augmentation are discussed. This volume provides novel insights into brain disorders, and new devices for brain repair. Information in this book is relevant to researchers in the field of neuroscience, engineering, and clinical practice. Philosophical and ethical implications of brain augmentation are also addressed. “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” – Ray Kurzweil "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " – Ioan Dumitrache “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” – György Buzsáki.
    Type of Medium: Online Resource
    Pages: XXII, 747 p. 189 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030545642
    Series Statement: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-030-54564-2
    DOI: 10.1007/978-3-030-54564-2
    DDC: 612.8
    Language: English
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    Frailty and Cardiovascular Diseases : Research into an Elderly Population (2020)
    Cham :Springer International Publishing :
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    Keywords: Geriatrics. ; Geriatric nursing. ; Cardiology. ; Epidemiology. ; Geriatrics. ; Geriatric Care. ; Cardiology. ; Epidemiology.
    Description / Table of Contents: Preface -- Frailty: what is it?- Tools for assessing frailty in older people: general concepts -- Epidemiology of frailty in older people -- Epidemiology of cardiovascular diseases in the elderly -- The impact of frailty on the role of the classical cardiovascular risk factors -- Frailty as cardiovascular risk factor (and vice versa) -- Inflammation, frailty and cardiovascular disease -- Oxidative stress, frailty and cardiovascular disease: current evidence -- The importance of cellular senescence in frailty and cardiovascular diseases -- Comprehensive geriatric assessment in cardiovascular disease -- Frailty in cardiac surgery -- Physical exercise for frailty and cardiovascular disease -- Cardiac rehabilitation for frail older people -- Future perspectives.
    Abstract: This book aims to clarify the potential association between frailty and cardiovascular disease in older people. Covering the biological as well as the clinical point of view, it allows researchers and clinicians to discover the significance of this topic. The contributions cover the most important aspects in the potential relationship between frailty and cardiovascular disease. In particular, authoritative authors in this field have clarified the definition and the epidemiology of frailty and cardiovascular disease in older people. A large part of the volume is dedicated to the biological mechanisms of frailty and cardiovascular disease, trying to find those in common between these two conditions. Since this book is dedicated to both researchers and clinicians, we have proposed some chapters to the importance of comprehensive geriatric assessment in the evaluation and treatment of cardiovascular diseases and frailty. In this regard, the importance of geriatric evaluation in cardiac surgery for older people is well covered. Finally, the importance of cardiac rehabilitation and physical exercise is summarized, being, actually, the most important treatments for both frailty and cardiovascular disease. Written by many well-known and widely published experts in their respective fields, this book will appeal to a wide readership such as researchers in the field and clinicians, especially suited in geriatric medicine and cardiology who, every day, face frail older patients. .
    Type of Medium: Online Resource
    Pages: VIII, 154 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030333300
    Series Statement: Advances in Experimental Medicine and Biology, 1216
    URL: https://doi.org/10.1007/978-3-030-33330-0
    DOI: 10.1007/978-3-030-33330-0
    DDC: 618.97
    Language: English
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    Tumor Microenvironment : Extracellular Matrix Components – Part A (2020)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Stem cells. ; Regenerative medicine. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: The tumor microenvironment: focus on extracellular matrix -- Keratan Sulphate in the Tumour Environment -- Hyaluronan in the tumor microenvironment -- Fibronectin in the tumor microenvironment -- Matrix metalloproteinases role in tumor microenvironment -- Flipping the Molecular Switch: Influence of Perlecan and its Modifiers in the Tumor Microenvironment -- Heparan sulfate in the tumor microenvironment -- The role of Glypican-1 in the tumour microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components with the tumor during cancer development. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include heparan sulphate, hyaluronan, fibronectin, perlecan, glypican, matrix metalloproteinases, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part A updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newer generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book will be an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapter authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.
    Type of Medium: Online Resource
    Pages: XI, 181 p. 29 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030401467
    Series Statement: Advances in Experimental Medicine and Biology, 1245
    URL: https://doi.org/10.1007/978-3-030-40146-7
    DOI: 10.1007/978-3-030-40146-7
    DDC: 571.978
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    A Faunal Review of Aleocharine Beetles in the Rapidly Changing Arctic and Subarctic Regions of North America (Coleoptera, Staphylinidae) (2021)
    Cham :Springer International Publishing :
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    Keywords: Zoology. ; Environment. ; Bioinformatics. ; Ecology . ; Biodiversity. ; Physical geography. ; Zoology. ; Environmental Sciences. ; Computational and Systems Biology. ; Ecology. ; Biodiversity. ; Earth System Sciences.
    Description / Table of Contents: Introduction -- Historical review of research on Arctic and Subarctic Aleocharinae -- Material and methods -- Impact of climate change on northern fauna and flora -- Aleocharinae as indicators of change -- Faunal analysis and discussion -- Key to tribes occurring in Arctic and Subarctic zones -- Tribe Gymnusini Heer, 1839 -- Tribe Aleocharini Fleming, 1821 -- Tribe Oxypodini C.G. Thomson, 1859 -- Tribe Tachyusini C.G. Thomson, 1859 -- Tribe Hypocyphtini Laporte, 1835 -- Tribe Myllaenini Ganglbauer, 1895 -- Tribe Liparocephalini Fenyes, 1918 -- Tribe Homalotini Heer, 1839 -- Tribe Placusini Mulsant and Rey, 1871 -- Tribe Athetini Casey, 1910 -- Tribe Falagriini Mulsant and Rey, 1873.
    Abstract: Arctic and Subarctic North America is particularly affected by climate change, where average temperatures are rising three times faster than the global average. Documenting the changing climate/environment of the north requires a structured knowledge of indicator taxa that reflect the effects of climate changes. Aleocharine beetles are a dominant group of forest insects, which are being used in many projects as indicators of environmental change. Many species are forest specialists restricted to certain microhabitats, some are generalists and others are open habitat specialists. They represent many ecological niches and, as such, are good indicators for many other species as well. The majority of Canadian aleocharine beetle species (about 600 spp.) has been studied and published by Jan Klimaszewski et al. (2018, 2020), mainly from southern, central, and western Canada, while the northern taxa remain poorly known and documented. The aim of the present book is to summarize the knowledge on this insect group in the Arctic and Subarctic North America and to provide a diagnostic and ecological tool for scientists studying and monitoring insects in northern Canada and Alaska. The book includes a review of the literature, information on 238 species and their habitats, taxonomic review, images, and identification tools.
    Type of Medium: Online Resource
    Pages: XIV, 712 p. 315 illus., 307 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030681913
    URL: https://doi.org/10.1007/978-3-030-68191-3
    DOI: 10.1007/978-3-030-68191-3
    DDC: 590
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    Molecular Mechanisms in Spermatogenesis (2021)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Reproductive health. ; Cytology. ; Biomedical Research. ; Reproductive Medicine. ; Cell Biology.
    Description / Table of Contents: Ch 1: The seminiferous epithelial cycle of spermatogenesis: Role of non-receptor protein kinases -- Ch 2: Sertoli cells: immunology and spermatogenesis -- Ch 3: Innate immunity and spermatogenesis -- Ch 4: Cell apoptosis and spermatogenesis -- Ch 5: Transcriptional regulation of spermatogenesis -- Ch 6: Sertoli cell cytoskeleton and spermatogenesis -- Ch 7: Leydig cell and spermatogenesis -- Ch 8: Cross-talk of cell junctions to support spermatogenesis -- Ch 9: Coordination of F-actin- and MT-based cytoskeletons to support spermatogenesis -- Ch 10: Regulation of the blood-testis barrier by basement membrane laminin-α2 chain -- Ch 11: Regulation of spermatogenesis by collagens -- Ch 12: Androgen regulation of spermatogenesis -- Ch 13: Use of molecular modeling to study spermatogenesis -- Ch 14: Acrosome biogenesis during spermatogenesis -- Ch 15: Stem cells and spermatogenesis -- Ch 16: Advances in our understanding of spermatogenesis in humans -- Ch 17: Leydig cell function in aging men -- Ch 18: Regulation of human spermatogenesis.
    Abstract: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
    Type of Medium: Online Resource
    Pages: X, 319 p. 44 illus., 40 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030777791
    Series Statement: Advances in Experimental Medicine and Biology, 1381
    URL: https://doi.org/10.1007/978-3-030-77779-1
    DOI: 10.1007/978-3-030-77779-1
    DDC: 610.72
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    Recent Developments on Genus Chaetomium (2020)
    Cham :Springer International Publishing :
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    Keywords: Fungi. ; Mycology. ; Microbiology. ; Plant genetics. ; Plant biotechnology. ; Plants Evolution. ; Plants Development. ; Fungi. ; Plant Genetics. ; Plant Biotechnology. ; Plant Evolution. ; Plant Development.
    Description / Table of Contents: Foreword -- Part 1. Chaetomium: Biology to biotechnology -- Chapter 1. Taxonomy and Biodiversity of the Genus Chaetomium in Different Habitats -- Chapter 2. Developmental Morphology of Chaetomium and Chaetomiopsis -- Chapter 3. Molecular approaches for analyzing environmental Chaetomium diversity and exploitation of Chaetomium thermophilum for biochemical analyses -- Chapter 4. Recent advances on occurrence of genus Chaetomium on dung -- Chapter 5. Chaetomium in indoor environment and medically important species of Chaetomium -- Part 2. Metabolites of Chaetomium, the good, the bad and the ugly -- Chapter 6. Recent advancements on the role of biologically active secondary metabolites from Chaetomium -- Chapter 7. Chaetomium’s alkaloids -- Chapter 8. Applications of Chaetomium functional metabolites with special reference to antioxidants -- Chapter 9. Chaetomium enzymes and their applications -- Chapter 10. The use of Chaetomium taxa as biocontrol agents -- Chapter 11. Nanoparticles mediated Chaetomium, unique multifunctional Bullets: What Do We Need for Real Applications in Agriculture? -- Chapter 12. Biodegradation of agricultural wastes by Chaetomium species -- Chapter 13. Bioconversion of lignocellulosic residues into Single-Cell Protein (SCP) by Chaetomium -- Chapter 14. LIGHT, Electromagnetic Spectrum and Photostimulation of Microorganisms with special reference to Chaetomium -- Chapter 15. Chaetomium as potential soft rot degrader of woody and papery cultural heritage -- Chapter 16. Thermophilic Chaetomium in biotechnology -- Index.
    Abstract: Chaetomium genus was established by Gustav Kunze in 1817. According to Index Fungorum Partnership, there are 273 Chaetomium species accepted till now. Members of the genus Chaetomium are capable of colonizing various substrates and are well-known for their ability to degrade cellulose and to produce a variety of bioactive metabolites. More than 200 compounds have been reported from this genus. A huge number of new and bioactive secondary metabolites associated with unique and diverse structural types, such as chaetoglobosins, epipolythiodioxopiperazines, azaphilones, depsidones, xanthones, anthraquinones, chromones, and steroids, have been isolated and identified. Many of the compounds have been reported to possess significant biological activities, such as antitumor, antimalarial, cytotoxic, enzyme inhibitory, antimicrobial, phytotoxic, antirheumatoid and other activities. Chaetomium taxa are frequently reported to be cellulase and ligninase producers with the ability to degrade cellulosic and woody materials. This is the first, comprehensive volume covering Chaetomium genus in detail. It includes the latest research, methods, and applications, and was written by scholars working directly in the field. The book also contains informative illustrations and is fully referenced for further reading.
    Type of Medium: Online Resource
    Pages: XVI, 452 p. 121 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030316129
    Series Statement: Fungal Biology,
    URL: https://doi.org/10.1007/978-3-030-31612-9
    DOI: 10.1007/978-3-030-31612-9
    DDC: 579.5
    Language: English
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    The Duckweed Genomes (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Plant genetics. ; Plant biotechnology. ; Agriculture. ; Plant Genetics. ; Plant Biotechnology. ; Agriculture.
    Description / Table of Contents: Importance of duckweeds in basic research and its industrial applications -- Background history of the international Spirodela genome sequencing initiatives -- Cytogenetics and karyotype evolution of duckweeds -- Duckweed organelle genomes -- Repetitive sequences: Impacts and uses in the Spirodela genome -- Genotyping by sequencing of duckweeds -- Genome and transcriptome of Landoltia punctata -- Transcriptome responses of Spirodela polyrhiza -- Strategies & tools for sequencing duckweeds -- Transformation development in duckweeds.
    Abstract: This book tells the story behind the first Spirodela genome sequencing project. Further, it describes the current genomics applications of these findings, and efforts to sequence new genomes within the family. The closing chapters address the sequencing of the over 1 Gigabase Wolffia genomes, which could have major impacts on genome evolution and agricultural research. The duckweed or Lemnaceae family is a collection of 5 genera and 37 species of the smallest, fastest-growing flowering plants. Many of these aquatic monocotyledonous plants can grow all over the world, in a variety of climates. Given their simplified and neotenous morphology, duckweeds have been researched for several decades as a model species for plant physiology and ecotoxicological research, contributing to our understanding e.g. of flowering response, plant circadian systems, sulfur assimilation pathways and auxin biosynthesis. In addition, duckweed-based treatment has been a favorite and feasible means, especially in developing countries, of removing phosphorus and pharmaceutical chemicals from sewage and wastewater. With a dry annual mass yield per hectare of up to 80 tonnes (equivalent to 10 tonnes of protein), duckweed is also a promising aquatic crop in new modern and sustainable agriculture. Besides being an excellent primary or supplemental feedstock for the production of livestock and fish, duckweed biomass can be utilized as a potential resource for human nutrition, biofuel, or bioplastics, depending on water quality as well as protein or starch accumulating procedures. These academic and commercial interests have led to international efforts to sequence the Spirodela polyrhiza genome, the smallest and most ancient genome in the family.
    Type of Medium: Online Resource
    Pages: XVIII, 185 p. 30 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030110451
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-11045-1
    DOI: 10.1007/978-3-030-11045-1
    DDC: 581.35
    Language: English
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    Deep Learning in Medical Image Analysis : Challenges and Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Biomedical engineering. ; Radiology. ; Bioinformatics. ; Biotechnology. ; Biomedical Engineering and Bioengineering. ; Radiology. ; Computational and Systems Biology.
    Description / Table of Contents: Deep Learning in Medical Image Analysis -- Medical Image Synthesis via Deep Learning -- Deep Learning for Pulmonary Image Analysis: Classification, Detection, and Segmentation -- Deep Learning Computer Aided Diagnosis for Breast Lesion in Digital Mammogram -- Decision support system for lung cancer using PET/CT and microscopic images -- Lesion Image Synthesis using DCGANs for Metastatic Liver Cancer Detection -- Retinopathy analysis based on deep convolution neural network -- Diagnosis of Glaucoma on retinal fundus images using deep learning: detection of nerve fiber layer defect and optic disc analysis -- Automatic segmentation of multiple organs on 3D CT images by using deep learning approaches -- Techniques and Applications in Skin OCT Analysis -- Deep Learning Technique for Musculoskeletal Analysis -- Index.
    Abstract: This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.
    Type of Medium: Online Resource
    Pages: VIII, 181 p. 131 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030331283
    Series Statement: Advances in Experimental Medicine and Biology, 1213
    URL: https://doi.org/10.1007/978-3-030-33128-3
    DOI: 10.1007/978-3-030-33128-3
    DDC: 660.6
    Language: English
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    The Tobacco Plant Genome (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Plant genetics. ; Plant biotechnology. ; Agriculture. ; Plant Genetics. ; Plant Biotechnology. ; Agriculture.
    Description / Table of Contents: Background and History of Tobacco -- Biodiversity of tobacco -- Genetics of tobacco -- The genome and transcriptome of tobacco and its ancestors -- SGN Tobacco resources and Nicotiana metabolic databases -- Leaf curing: a key step for tobacco chemistry -- Repetitive DNA dynamics and polyploidization in the genus Nicotiana (Solanaceae) -- Interspecific introgression in Nicotiana species -- Nicotine biosynthesis, transpssort, and regulation in tobacco: insights into the evolution of a metabolic pathway.
    Abstract: This book describes the history of tobacco genomics, from its “discovery” by Europeans to next-generation omics approaches in plant science. The authors primarily focus on the allotetraploid common tobacco plant (N. tabacum); however, separate chapters are dedicated to closely related Nicotiana species, such as N. benthamiana and N. attenuata, for which substantial progress in omics data analysis has been already achieved. While genetic maps, transcriptomes, and physical maps of BAC libraries have significantly enhanced our understanding of the tobacco plant, the genome of tobacco and related Nicotiana species has opened a new era in modern tobacco research. This book addresses current and future industrial and research applications as well as central challenges in tobacco science, including diseases, low variability of cultivars, the genome’s large size, polyploidy, and gene duplication.
    Type of Medium: Online Resource
    Pages: XIV, 263 p. 57 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030294939
    Series Statement: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-29493-9
    DOI: 10.1007/978-3-030-29493-9
    DDC: 581.35
    Language: English
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    The Evolution of Feathers : From Their Origin to the Present (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Evolution (Biology). ; Paleontology . ; Anatomy, Comparative. ; Vertebrates. ; Animal migration. ; Physiology. ; Evolutionary Biology. ; Paleontology. ; Animal Anatomy. ; Vertebrate Zoology. ; Animal Migration. ; Animal Physiology.
    Description / Table of Contents: 1. Introduction to the morphology, development, and ecology of feathers -- 2. Molecular and cellular mechanisms of feather development provide a basis for diverse evolution of feather forms -- 3. The origin of birds: current consensus, controversy, and the occurrence of feathers -- 4. Integumentary structures in Kulindadromeus zabaikalicus, a basal neornithischian dinosaur from the Jurassic of Siberia -- 5. Filamentous integuments in non-avialan theropods and their kin: advances and future perspectives for understanding the evolution of feathers -- 6. Two of a feather: A comparison of the preserved integument in the juvenile theropod dinosaurs Sciurumimus and Juravenator from the Kimmeridgian Torleite Formation of southern Germany -- 7. Feather evolution in Pennaraptora -- 8. The feathers of the Jurassic Urvogel Archaeopteryx -- 9. The plumage of basal birds -- 10. A morphological review of the enigmatic elongated tail feathers of stem birds -- 11. Review on color patterns of fossil feathers -- 12. On the ancestry of feathers in Mesozoic dinosaurs.
    Abstract: Feathers are one of the most unique characteristics of modern birds and represent the most complex and colourful type of skin derivate within vertebrates, while also fulfilling various biological roles, including flight, thermal insulation, display, and sensory function. For years it was generally assumed that the origin of flight was the main driving force for the evolution of feathers. However, various discoveries of dinosaur species with filamentous body coverings, made over the past 20 years, have fundamentally challenged this idea and produced new evolutionary scenarios for the origin of feathers. This book is devoted to the origin and evolution of feathers, and highlights the impact of palaeontology on this research field by reviewing a number of spectacular fossil discoveries that document the increasing morphological complexity along the evolutionary path to modern birds. Also featuring chapters on fossil feather colours, feather development and its genetic control, the book offers a timely and comprehensive overview of this popular research topic. .
    Type of Medium: Online Resource
    Pages: VIII, 243 p. 80 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030272234
    Series Statement: Fascinating Life Sciences,
    URL: https://doi.org/10.1007/978-3-030-27223-4
    DOI: 10.1007/978-3-030-27223-4
    DDC: 576.8
    Language: English
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    Integrated Pest and Disease Management in Greenhouse Crops (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Plant diseases. ; Invertebrates. ; Agriculture. ; Plant Pathology. ; Invertebrate Zoology. ; Agriculture.
    Description / Table of Contents: Introduction . M.L. Gullino, R. Albajes, P. Nicot, J.C. van Lenteren -- Chapter1. Viral diseases. E. Moriones, E. Verdin -- Chapter2. Bacterial diseases. V. Catara, P. Bella -- Chapter3. Fungal diseases. M. Bardin, M.L. Gullino -- Chapter4. Insect and mite pests. M. Knapp, E. Palevsky, C. Rapisarda -- Chapter 5. Nematodes. F.X. Sorribas, C. Djian-Caporalino, T. Mateille -- Chapter6. Integrated Pest Management methods and considerations concerning implementation in greenhouses. J. Van Lenteren, P. Nicot -- Chapter7. 1. Epidemiology and population dynamics: modelisation, monitoring and management. G. Marchand, P.C. Nicot, R. Albajes, O. Carisse -- Chapter8. Diagnostics and identification of diseases, insects and mites. D. Spadaro, N. Agustí, S. F. Ortega, M.A. Hurtado Ruiz -- Chapter9. Host plant resistance to pests and pathogens, the genetic leverage in integrated pest and disease management. V. Lefebvre, N. Boissot, J-L. Gallois -- Chapter10. Cultural methods for greenhouse pest and disease management. M. Kruidhof, W.H. Elmer -- Chapter11Seed and Propagative material. G. Munkvold, M.L. Gullino -- Chapter12. Soil and substrate health. A. Gamliel -- Chapter13. Biocontrol agents against diseases. M. Bardin, M. Pugliese -- Chapter14. Biological control agents for control of pests in greenhouses. J. Van Lenteren, Ò. Alomar, W. Ravensberg, A. Urbaneja -- Chapter15. Chemical and natural pesticides in IPM: side-effects and application. M.L. Gullino, L. Tavella -- Chapter16. Implementation of IPDM in greenhouses: from research to the consumer. J. Riudavets, E. Moerman, E. Villa -- Chapter17. Tomatoes. C. Castañé, J. Van der Bloom, P.C. Nicot -- Chapter18. Sweet peppers. G. Messelink, R. Labbe, G. Marchand, L. Tavella -- Chapter19. Cucurbits. G. Messelink, F.J. Calvo, F. Marín, D.Janssen -- Chapter20. IPM for protecting leafy vegetables under greenhouses. B. Gard, G. Gilardi -- Chapter21. Implementation of IPDM in strawberries and other berries. S.K. Dara -- Chapter22. Ornamentals. M. Daughthrey, R. Buitenhuis -- Chapter23. Implementation of IPDM in greenhouses: customer value as guideline. J.S. Buurma and N.J.A. van der Velden -- Conclusion.
    Abstract: This book represents a new, completely updated, version of a book edited by two of the current editors, published with Springer in 1999. It covers pest and disease management of greenhouse crops, providing readers the basic strategies and tactics of integrated control together with its implementation in practice, with case studies with selected crops. The diversity of editors and authors provides readers a complete picture of the world situation of IPM in greenhouse crops. .
    Type of Medium: Online Resource
    Pages: IX, 691 p. 56 illus., 44 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030223045
    Series Statement: Plant Pathology in the 21st Century, 9
    URL: https://doi.org/10.1007/978-3-030-22304-5
    DOI: 10.1007/978-3-030-22304-5
    DDC: 571.92
    Language: English
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    Models of Tree and Stand Dynamics : Theory, Formulation and Application (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Applied ecology. ; Forestry. ; Plant ecology. ; Ecology . ; Applied Ecology. ; Forestry. ; Plant Ecology. ; Theoretical and Statistical Ecology.
    Description / Table of Contents: Preface -- List of symbols -- 1. Introduction -- 2. Descriptive Models -- 3. Carbon Balance -- 4. Tree Structure -- 5. Carbon Balance and Structure -- 6. Competition -- 7. Tree structure revisited: Eco-evolutionary models -- 8. Predicting stand growth: parameters, drivers and modular inputs -- 9. Calibration -- 10. Applications and future outlook -- Solutions to Exercises -- References -- Author Index -- Index.
    Abstract: The book is designed to be a textbook for university students (MSc-PhD level) and a reference for researchers and practitioners. It is an introduction to dynamic modelling of forest growth based on ecological theory but aiming for practical applications for forest management under environmental change. It is largely based on the work and research findings of the authors, but it also covers a wide range of literature relevant to process-based forest modelling in general. The models presented in the book also serve as tools for research and can be elaborated further as new research findings emerge. The material in the book is arranged such that the student starts from basic concepts and formulations, then moves towards more advanced theories and methods, finally learning about parameter estimation, model testing, and practical application. Exercises with solutions and hands-on R-code are provided to help the student digest the concepts and become proficient with the methods. The book should be useful for both forest ecologists who want to become modellers, and for applied mathematicians who want to learn about forest ecology. The basic concepts and theory are formulated in the first four chapters, including a review of traditional descriptive forest models, basic concepts of carbon balance modelling applied to trees, and theories and models of tree and forest structure. Chapter 5 provides a synthesis in the form of a core model which is further elaborated and applied in the subsequent chapters. The more advanced theories and methods in Chapters 6 and 7 comprise aspects of competition through tree interactions, and eco-evolutionary modelling, including optimisation and game theory, a topical and fast developing area of ecological modelling under climate change. Chapters 8 and 9 are devoted to parameter estimation and model calibration, showing how empirical and process-based methods and related data sources can be bridged to provide reliable predictions. Chapter 10 demonstrates some practical applications and possible future development paths of the approach. The approach in this book is unique in that the models presented are based on ecological theory and research findings, yet sufficiently simple in structure to lend themselves readily to practical application, such as regional estimates of harvest potential, or satellite-based monitoring of growth. The applicability is also related to the objective of bridging empirical and process-based approaches through data assimilation methods that combine research-based ecological measurements with standard forestry data. Importantly, the ecological basis means that it is possible to build on the existing models to advance the approach as new research findings become available. .
    Type of Medium: Online Resource
    Pages: XVI, 310 p. 116 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357610
    URL: https://doi.org/10.1007/978-3-030-35761-0
    DOI: 10.1007/978-3-030-35761-0
    DDC: 333.9516
    Language: English
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    Experimental Design and Reproducibility in Preclinical Animal Studies (2021)
    Cham :Springer International Publishing :
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    Keywords: Veterinary medicine. ; Medicine Research. ; Biology Research. ; Biometry. ; Veterinary Science. ; Biomedical Research. ; Biostatistics.
    Description / Table of Contents: An introduction to reproducibility in the context of animal research -- Rodent Genetics -- Animal and environmental factors that influence reproducibility -- Microbiology and Microbiome -- Effects of untreated pain, anesthesia and analgesia in animal experimentation -- Why do we need a statistical experiment design -- Statistical tests and Sample size calculations -- Design of experiments -- Scholarly Publishing and Scientific Reproducibility -- Systematic reviews -- Planning animal experiments.
    Abstract: This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches on factors that may impact the reproducibility of animal studies including: the animal genetic background, the animal microbial flora, environmental and physiological variables affecting the animal, animal welfare, statistics and experimental design, systematic reviews of animal studies, and the publishing process. The book addresses advanced undergraduates, graduate students and all scientists working with animals.
    Type of Medium: Online Resource
    Pages: VI, 277 p. 52 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030661472
    Series Statement: Laboratory Animal Science and Medicine, 1
    URL: https://doi.org/10.1007/978-3-030-66147-2
    DOI: 10.1007/978-3-030-66147-2
    DDC: 636.089
    Language: English
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    Antarctic Seaweeds : Diversity, Adaptation and Ecosystem Services (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Freshwater ecology. ; Marine ecology. ; Plant physiology. ; Biotic communities. ; Population biology. ; Plant ecology. ; Freshwater and Marine Ecology. ; Plant Physiology. ; Community and Population Ecology. ; Plant Ecology.
    Description / Table of Contents: Antarctic Seaweeds: Biogeography, Adaptation and Ecosystem Services -- Diversity of Antarctic Seaweeds -- Biogeographic Processes Influencing Antarctic and Sub-Antarctic Seaweeds -- Detached Seaweeds as Important Dispersal Agents Across the Southern Ocean.-Biogeography of Antarctic Seaweeds Facing Climate Changes -- Comparative Phylogeography of Antarctic Seaweeds: Genetic Consequences of Historical Climatic Variations -- Underwater Light Environment of Antarctic Seaweeds -- Production and Biomass of Seaweeds in Newly Ice-Free Areas: Implications for Coastal Processes in a Changing Antarctic Environment -- Carbon Balance Under a Changing Light Environment -- Life History Strategies, Photosynthesis and Stress Tolerance in Propagules of Antarctic Seaweeds -- Form and Function in Antarctic Seaweeds: Photobiological Adaptations, Zonation Patterns and Ecosystem Feedbacks -- Successional Processes in Antarctic Benthic Algae -- Seaweed-Herbivore Interactions: Grazing as Biotic Filtering in Intertidal Antarctic Ecosystems -- Diversity and Functioning of Antarctic Seaweed Microbiomes -- Seaweeds in the Antarctic Marine Coastal Food Web -- Trophic Networks and Ecosystem Functioning -- Chemical Mediation of Antarctic Macroalgal-Grazer Interactions -- Brown Algal Phlorotannins: An Overview of their Functional Roles.
    Abstract: Seaweeds (macroalgae) represent the most striking living components in the Antarctic’s near-shore ecosystems, especially across the West Antarctic Peninsula and adjacent islands. Due to their abundance, their central roles as primary producers and foundation organisms, and as sources of diverse metabolically active products, seaweed assemblages are fundamental to biogeochemical cycles in Antarctic coastal systems. In recent years, the imminence of climate change and the direct impacts of human beings, which are affecting vast regions of the Antarctic, have highlighted the importance of seaweed processes in connection with biodiversity, adaptation and interactions in the benthic network. Various research groups have been actively involved in the investigation of these topics. Many of these research efforts have a long tradition, while some “newcomers” have also recently contributed important new approaches to the study of these organisms, benefiting polar science as a whole. This book provides an overview of recent advances and insights gleaned over the past several years. Focusing on a timely topic and extremely valuable resource, it assesses the challenges and outlines future directions in the study of Antarctic seaweeds.
    Type of Medium: Online Resource
    Pages: XIV, 397 p. 68 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030394486
    URL: https://doi.org/10.1007/978-3-030-39448-6
    DOI: 10.1007/978-3-030-39448-6
    DDC: 577.6
    Language: English
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    Molecular Mechanisms of Retina Pathology and Ways of its Correction (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cytology. ; Pharmacy. ; Biomedical Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cell Biology. ; Pharmacy.
    Description / Table of Contents: Chapter 1. Literature review -- Chapter 2. Results of experimental studies of short peptides (cytogens) in ophthalmology -- Chapter 3. Results of the clinical study of short peptides (cytogens) in ophthalmology -- Conclusion.
    Abstract: This book discusses the pathology of the retina, and reviews current research on the use of cell replacement therapy and short peptides to restore functional activity in retinal neurons. As the book describes, pathologies of the retina, including age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, present a long-standing challenge in the practice of clinical ophthalmology. Modern treatment for these conditions, which lead to irreversible blindness, includes laser exposure, surgical intervention, and drugs. These treatments aim to reduce the risk of new complications in the eye; pathogenetic therapy of degenerative diseases of the retina is practically absent in current ophthalmic practice. The first section of the book reviews the molecular mechanisms of age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, and reports on methods of treatment. The second section presents the results of recent experimental studies of the effects of short peptides on pluripotent embryonic cells; on proliferative activity in retinal cells and pigment epithelium; on expression of markers of differentiation or retinal neurons and pigment epithelium; and on the course of hereditary retinal pigmentation in Campbell rats. The third section offers results of clinical studies on the effectiveness of short peptides in patients with macular degeneration, and in patients with retinitis pigmentosa. The author concludes that the regular use of peptides in the treatment of degenerative diseases of the retina can slow the progression of the pathological process and preserve the patient’s vision for some 10-15 years. In addition, in 80 percent of patients, it is possible to increase visual function by increasing visual acuity, improving the boundaries of the visual field and the fundus.
    Type of Medium: Online Resource
    Pages: VI, 90 p. 17 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030501600
    URL: https://doi.org/10.1007/978-3-030-50160-0
    DOI: 10.1007/978-3-030-50160-0
    DDC: 610.72
    Language: English
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    Current Advances in the Science of Osteosarcoma : Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Medical microbiology. ; Cytology. ; Pediatrics. ; Cancer Biology. ; Medical Microbiology. ; Cell Biology. ; Pediatrics.
    Description / Table of Contents: The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies -- Genomics and the Immune Landscape of Osteosarcoma -- RECQ DNA Helicases and Osteosarcoma -- Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma -- Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma -- Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response -- Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma -- Wnt Signaling in Osteosarcoma -- Receptor Tyrosine Kinases in Osteosarcoma: 2019 update -- The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets -- Autophagy in OS -- Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs -- Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment -- Comparative Immunology and Immunotherapy of Canine Osteosarcoma -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.
    Type of Medium: Online Resource
    Pages: XIII, 233 p. 34 illus., 23 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030430856
    Series Statement: Advances in Experimental Medicine and Biology, 1258
    URL: https://doi.org/10.1007/978-3-030-43085-6
    DOI: 10.1007/978-3-030-43085-6
    DDC: 571.978
    Language: English
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    Lizards of Patagonia : Diversity, Systematics, Biogeography and Biology of the Reptiles at the End of the World (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Evolution (Biology). ; Vertebrates. ; Biodiversity. ; Animal migration. ; Conservation biology. ; Ecology . ; Evolutionary Theory. ; Vertebrate Zoology. ; Biodiversity. ; Animal Migration. ; Conservation Biology.
    Description / Table of Contents: Section I - Historical and general background -1) History of Discovery of the Patagonian Lizards -- 2) Lizards within the cultural and symbolic context of Patagonia -- Section II - Land, climate and vegetation background - 3) Landscapes and geology, a general introduction to the land of reptiles -- 4) Paleoclimatology of Patagonia since the Cretaceous to the Holocene -- 5) Geographical singularities of the Patagonian climate -- 6) Major phytogeographic units of Patagonia -- 7) The Patagonian fossil lizards -- Section III - Diversity and current knowledge of Patagonian lizards - 8) Naming the diversity: taxonomy of current species of Patagonian lizards -- 9) Phylogenetics, phylogeography and biogeography of Patagonian Steppe lizards -- 10) Phylogeography of lizards in Chile: the role of the history of geographic space on the distribution of its intraspecific diversity -- 11) General ecology of Patagonian lizards -- 12) Reproductive biology of lizards from cold and harsh environments of Patagonia Argentina -- 13) Effects of global warming on ecophysiology of lizards of Patagonia, Argentina -- 14) Conservation of lizards from Patagonia: current status, trends and management proposals.
    Abstract: This book presents a critical and integrated review of lizards from Patagonia. It summarizes the region’s geomorphological history and climatic aspects, which makes it possible to interpret, from an evolutionary perspective, the latest findings on the various natural history aspects of its lizard fauna. As such, the book will appeal to all researchers and professionals specialized in lizard ecology and evolution.
    Type of Medium: Online Resource
    Pages: XX, 432 p. 112 illus., 99 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030427528
    Series Statement: Natural and Social Sciences of Patagonia,
    URL: https://doi.org/10.1007/978-3-030-42752-8
    DOI: 10.1007/978-3-030-42752-8
    DDC: 576.801
    Language: English
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    Advanced Concepts in Human Immunology: Prospects for Disease Control (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Pharmacology. ; Diseases. ; Cancer. ; Immunology. ; Pharmacology. ; Diseases. ; Cancer Biology.
    Description / Table of Contents: 1. Human Chronic Viruses: Pathogenesis, host response, and treatment -- 2. Defining the Role of Immunoproteomics in Human Immunotherapy -- 3. Microbiome and Cellular Players in Type 1 Diabetes: from Pathogenesis to Protection -- 4. Immune Mechanisms, Pathology, and Management of Allergic Ocular Diseases -- 5. Dendritic Cell-regulated T Cell Immunity and Tolerance against Acute Myeloid Leukemia -- 6. Perspectives on the Role of T cell Negative Immune Checkpoint Receptors in Health and Disease -- 7. Neuroprotective Immunity for Neurodegenerative and Neuroinfectious Diseases -- 8. Polycystic Ovary Syndrome: An overview of a complex, heterogeneous genetic condition.
    Abstract: This book highlights information derived primarily from clinical samples, with particular reference to theoretical and scientific aspects of the human immune system. This text will focus on topics that range from host-pathogen interactions in infectious disease to host immune response in cancer, allergic diseases, neuroinflammatory diseases, and autoimmune disorders. The reader will also have a well-rounded understanding of the behavior of the immune system with particular emphasis on the role of immunoproteomics in immunotherapy, neuroprotective immunity for neurodegenerative and neuroinfectious disease, leukemia-associated dendritic cell induction of adaptive immunity dysregulation, and the role of immune checkpoint inhibitors in cancer, infection, as well as neuroinflammation. Taken together, the contents of this book are intended for both clinicians and researchers in academia and industry.
    Type of Medium: Online Resource
    Pages: XVIII, 403 p. 16 illus., 5 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339463
    URL: https://doi.org/10.1007/978-3-030-33946-3
    DOI: 10.1007/978-3-030-33946-3
    DDC: 571.96
    Language: English
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    Cell Biology and Translational Medicine, Volume 9 : Stem Cell-Based Therapeutic Approaches in Disease (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Stem cells. ; Regenerative medicine. ; Medical genetics. ; Biotechnology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Medical Genetics. ; Biotechnology.
    Description / Table of Contents: Data Analysis of Infection Rates Among Exposed Healthcare Workers Could Reveal Effective Prophylactics Against SARS-CoV-2 -- Immune Responses to SARS-CoV, MERS-CoV AND SARS-CoV-2 -- Normothermic Preservation of Liver – What does the Future Hold? -- Tissues from Post-Mortem Donors as Alternative Sources of Stem Cells for Regenerative Medicine -- New Pioneers of Optogenetics in Neuroscience -- A Current Overview of Scaffold-Based Bone Regeneration Strategies with Dental Stem Cells -- The Importance of Stem Cell Senescence in Regenerative Medicine -- Hematological Malignancies and Fertility -- Unraveling polymeric nanoparticles cell uptake pathways: two decades working to understand nanoparticles journey to improve gene therapy -- Cellular Dust as a Novel Hope for Regenerative Cancer Medicine.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the ninth volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 163 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030549176
    Series Statement: Cell Biology and Translational Medicine, 1288
    URL: https://doi.org/10.1007/978-3-030-54917-6
    DOI: 10.1007/978-3-030-54917-6
    DDC: 571.6
    Language: English
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    Gut Microbiome and Its Impact on Health and Diseases (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Food Microbiology. ; Food science. ; Nutrition   . ; Food Microbiology. ; Food Science. ; Nutrition.
    Description / Table of Contents: Contribution of human and animal to the microbial world and ecological balance -- Determinants of the Gut Microbiota -- Effects of Diet on Human Gut Microbiome and Subsequent Influence on Host 1 Physiology and Metabolism. -Probiotics and prebiotics on intestinal flora and gut health -- Role of the gut flora in human nutrition and gut health -- Gut microbiome in inflammation and chronic enteric infections -- Role of gut microbiome in colorectal cancer -- Gut microbiota and risk for atherosclerosis: current understanding of the mechanisms -- Gut microbiome and its role in enteric infections with microbial pathogens -- Antibiotic Therapy and its Effect on Gut Microbiome in Obesity and Weight loss -- Impact of gut microbiota on host through exploring proteomics -- Modulation of gut flora and its application in food animal products -- Index.
    Abstract: This book provides a comprehensive examination of the role of gut microbiome/microflora in nutrition, metabolism, disease prevention and health issues, including farm animal health and food value, and human gastrointestinal health and immunity. Indigenous microbiotas, particularly the gut microflora/microbiome, are an essential component in the modern concept of human and animal health. The diet and lifestyle of the host and environment have direct impact on gut microflora and the patterns of gut microbial colonization associated with health and diseases have been documented. Contributing authors cover the impact of gut microbiome in farm animal health, and explore the possibility of modulating the human gut microbiome with better animal products to prevent human diseases, including endemic and emerging diseases such as obesity, cancer and cardiac diseases. Dieting plan and control methods are examined, with attention paid to balance dieting with natural food and drink components. In addition, the role of gut microbiota in enteric microbial colonization and infections in farm animals is also discussed. The volume also explores the possibility of improving human health by modulating the microbiome with better food, including bio-active foods and appropriate forms of intake. Throughout the chapters, authors examine cutting edge research and technology, as well as future directions for better practices regarding emerging issues, such as the safety and production of organic food.
    Type of Medium: Online Resource
    Pages: VI, 288 p. 14 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030473846
    URL: https://doi.org/10.1007/978-3-030-47384-6
    DOI: 10.1007/978-3-030-47384-6
    DDC: 664.001579
    Language: English
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    Explaining Health Across the Sciences (2020)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Medicine Philosophy. ; Medical sciences. ; Science Philosophy. ; Biomedical Research. ; Philosophy of Medicine. ; Health Sciences. ; Philosophy of Science.
    Abstract: This edited volume aims to better understand the multifaceted phenomenon we call health. Going beyond simple views of health as the absence of disease or as complete well-being, this book unites scientists and philosophers. The contributions clarify the links between health and adaptation, robustness, resilience, or dynamic homeostasis, and discuss how to achieve health and healthy aging through practices such as hormesis. The book is divided into three parts and a conclusion: the first part explains health from within specific disciplines, the second part explores health from the perspective of a bodily part, system, function, or even the environment in which organisms live, and the final part looks at more clinical or practical perspectives. It thereby gathers, across 30 chapters, diverse perspectives from the broad fields of evolutionary and systems biology, immunology, and biogerontology, more specific areas such as odontology, cardiology, neurology, and public health, as well as philosophical reflections on mental health, sexuality, authenticity and medical theories. The overarching aim is to inform, inspire and encourage intellectuals from various disciplines to assess whether explanations in these disparate fields and across biological levels can be sufficiently systematized and unified to clarify the complexity of health. It will be particularly useful for medical graduates, philosophy graduates and research professionals in the life sciences and general medicine, as well as for upper-level graduate philosophy of science students.
    Type of Medium: Online Resource
    Pages: XVII, 555 p. 30 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030526634
    Series Statement: Healthy Ageing and Longevity, 12
    URL: https://doi.org/10.1007/978-3-030-52663-4
    DOI: 10.1007/978-3-030-52663-4
    DDC: 610.72
    Language: English
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    The Geography of Black Pepper (Piper nigrum) : The "King" of Spices – Volume 1 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Food science. ; Plant ecology. ; Economic geography. ; Agriculture. ; Plant Science. ; Food Science. ; Plant Ecology. ; Economic Geography. ; Agriculture.
    Description / Table of Contents: Preface -- Chapter 1 Introduction -- Chapter 2 The Pepper Plant—Its Botany and Chemistry -- Chapter 3 Pepper Agronomy -- Chapter 4 The Role of the Nutrient Buffer Power Concept in Pepper Nutrition -- Chapter 5 Establishing a Pepper Plantation -- Chapter 6 Pepper Pests and Their Control -- Chapter 7 The Processing of Black Pepper on Farm -- Chapter 8 An Account of Indonesian Pepper Processing -- Chapter 9 Industrial Processing of Black Pepper -- Chapter 10 The Future of the Global Pepper Economy -- Chapter 11 Pepper Economy in India -- Chapter 12 Pepper Pharmacopoeia -- Chapter 13 Consumer Products Out of Black Pepper -- Chapter 14 Value Addition in Pepper -- Chapter 15 Conclusions and a Peep Into Pepper’s Future -- PRECISE QUANTIFICATION OF PLANT NUTRIENT BIO AVAILABILITY FOR BLACK PEPPER AND CARDAMOM -- TECHNOLOGICAL INNOVATIONS IN SPICES RESEARCH AND DEVELOPMENT!!!.
    Abstract: This book considers all aspects of black pepper from its growth, as a flowering vine, to how the dried fruit (peppercorn) is used as a spice and traded as a commodity. It is the economic mainstay of several India states and, principally, in Kerala State, with the Indian subcontinent being the largest black pepper producer. Indonesia has also emerged as a large producer of black pepper. Black pepper commands a leading position among the spices and has an immense commercial importance to world trade, finding its way onto the dining table of millions around the world, on the European and North American continents, and Japan. The use of black pepper ranges from a simple dietary component and flavour enhancer, to that of a spice with huge pharmacological benefits. .
    Type of Medium: Online Resource
    Pages: XIV, 162 p. 24 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030528652
    URL: https://doi.org/10.1007/978-3-030-52865-2
    DOI: 10.1007/978-3-030-52865-2
    DDC: 580
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    Plant Microbiome Paradigm (2020)
    Cham :Springer International Publishing :
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    Keywords: Microbiology. ; Microbial ecology. ; Botany. ; Microbiology. ; Microbial Ecology. ; Plant Science.
    Description / Table of Contents: Interaction of Epiphyllic Bacteria with Plant Cuticles -- Plant Microbiome and Its Important in Stressful Agriculture -- Plant-Microbe Interactions: Applications for Plant‐Growth Promotion and In-Situ Agri-Waste Management -- Plant-Microbe-Metal Interactions: A Biochemical and Molecular Analysis for Phytoremediation -- Ecosystem Diversity as a Function of Plant and Soil-Microbe Interactions -- Plant Growth Promoting Potentials of Endophytic Fungi for the Management of Agricultural Crops and Grasses -- Biological Control of Plant Diseases: Opportunities and Limitations -- Circadian Redox Rhythms Play an Important Role in Plant-Pathogen Interaction -- Rhizospheric Microorganisms for the Remediation of Contaminants for Ecological Restoration -- The Rhizosphere Microbiome: Microbial Communities and Plant Health -- On the Possibility of Accelerating Succession by Manipulating Soil Microorganisms -- Composition and Dynamics of Microbial Communities in Fly Ash-Amended Soil -- Molecular Insight into Plant-Fungal Pathogen Interaction: Emerging Trends and Implication in Designing Climate Smart Filed Crops -- Biochemical Dynamics of Plant Microbe Interactions -- Endophytic Secondary Metabolites for Biological Control - A Latest Perspective.
    Abstract: This book provides a comprehensive overview of the current state of knowledge on plant-microbiome interactions and associations. It covers all major mechanistic approaches used to investigate microbes’ impacts on plant growth promotion, disease control and health. The industrial manufacture of nitrogen currently accounts for roughly 2% of the world’s total energy consumption. Microbial products are expected to reduce the need for costly fertilizers, as well as chemical pesticides and fungicides. While beneficial microorganisms are increasingly being used in agriculture, abiotic and biotic stresses such as heat, drought, cold, and salt can quickly kill or render them useless in the field. However, discovering new and better treatments is a lengthy process due to the considerable microbial diversity found in soils. Researchers have now proposed using biotechnological approaches to accelerate the process of microbial technology development. The fact that plant-associated microbes stimulate plant growth and development is well known, as the examples of rhizobia and mycorrhizal fungi show. The mechanisms by which these microorganisms maintain plant growth include the production of phytohormones, fixation of nitrogen, and the mobilization of phosphorus and minerals. The plant microbiome is also involved in pathogen suppression, and especially the root microbiome acts as a protective shield against soil-borne pathogens. A special feature of this book is its multidisciplinary approach, spanning from plant microbiology/biocontrol, fungal and bacterial endophytes, plant physiology, to biochemistry, proteomics and genomics. It is ideally suited for researchers and student of agri-biotechnology, soil biology and fungal biology.
    Type of Medium: Online Resource
    Pages: VI, 307 p. 31 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030503956
    URL: https://doi.org/10.1007/978-3-030-50395-6
    DOI: 10.1007/978-3-030-50395-6
    DDC: 579
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    Outbreak in the Village : A Family Doctor's Lifetime Study of Whooping Cough (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Life sciences. ; Pharmacology. ; Medical sciences. ; Medicine History. ; Public health. ; Immunology. ; Life Sciences. ; Pharmacology. ; Health Sciences. ; History of Medicine. ; Public Health.
    Description / Table of Contents: 1. Introduction -- 2. From Africa to England -- 3. The children's clinic at Keyworth -- 4. Whooping cough vaccine -- 5. 1977-79: The first outbreak of whooping cough -- 6. Does the vaccine work? -- 7. 1981: Whooping cough vaccine is very rarely harmful -- 8. 1981-83: The second outbreak. How many cases are there really? -- 9.1985-87: The third outbreak. The search for subclinical infection -- 10. Does the effectiveness of the vaccine wear off? -- 11. 1988: Trying to raise the uptake of pertussis vaccine -- 12. 1989-91: The fourth outbreak. The natural history of whooping cough -- 13. 1990's: Whooping cough fades away but new diagnostic tests emerge -- 14. 2000: Whoopingcough.net. Overcoming diagnostic paralysis -- 15. The early noughties: The new tests aid the rediscovery of whooping cough -- 16. Late noughties: "Resurgence" of whooping cough in the USA and Australia puts the UK on alert -- 17. 2012: Whooping cough diagnoses peak in the UK but remain unchanged in Keyworth -- 18. What lies ahead? -- 19. Epilogue -- Appendix.
    Abstract: Outbreak in the Village is a fascinating account of the personal and professional journey of Dr. Doug Jenkinson, physician and researcher. Over the course of four decades in practice, Jenkinson traces the reemergence of whooping cough in the developed world, using his practice in the idyllic English countryside as a clinical control group. Keeping meticulous notes and indulging an itch to investigate, he explores one of history's most enigmatic and pervasive diseases. Jenkinson relates the tale of his life's work amid winsome anecdotes, relevant history, and practical advice. Told in an amiable, engaging voice with an expert balance of levity and earnestness, this story will charm casual readers interested in medical history and memoir, as well as doctors and researchers who identify with the experiences and may benefit from the research and techniques employed. Readers will find themselves in the examination room beside Jenkinson as the investigation unfolds, learning about the nature of the illness and the sweeping detrimental effects of an anti-vaccination campaign. An intriguing memoir about a mysterious illness, a public health failure, and one doctor's quest for clarity, Outbreak in the Village is a tale of perseverance and objectivity sure to delight and inform. .
    Type of Medium: Online Resource
    Pages: XXIII, 158 p. 63 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030454852
    Series Statement: Springer Biographies,
    URL: https://doi.org/10.1007/978-3-030-45485-2
    DOI: 10.1007/978-3-030-45485-2
    DDC: 571.96
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    Cell Biology and Translational Medicine, Volume 10 : Stem Cells in Tissue Regeneration (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Cell Biology.
    Description / Table of Contents: Apelin Receptor Signaling During Mesoderm Development -- Epidermal stem cells in regenerative medicine -- The cellular and molecular patterns involved in the neural differentiation of adipose-derived stem cells -- Biomatrices for heart regeneration and cardiac tissue modelling in vitro -- Dentin-Pulp Tissue Regeneration Approaches in Dentistry: An Overview and Current Trends -- Stem Cell Culture under Simulated Microgravity -- Smart Polymeric Systems: A Biomedical Viewpoint -- Acute lung injury: Disease modelling and the therapeutic potential of stem cells -- COVID-19 and Mesenchymal Stem Cell Treatment; Mystery or Not -- PCDH19 pathogenic variants in males: Expanding the phenotypic spectrum.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the tenth volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VII, 191 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030600129
    Series Statement: Cell Biology and Translational Medicine, 1298
    URL: https://doi.org/10.1007/978-3-030-60012-9
    DOI: 10.1007/978-3-030-60012-9
    DDC: 571.6
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    Composite Materials: Applications in Engineering, Biomedicine and Food Science (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Food science. ; Biomaterials. ; Nanotechnology. ; Ceramic materials. ; Biotechnology. ; Food Science. ; Biomaterials. ; Nanotechnology. ; Ceramics.
    Description / Table of Contents: Carbon materials from various sources for composite materials -- Carbon Fibre Reinforced Polymer (CFRP) Composites: Machining Aspects and Opportunities for Manufacturing Industries -- Surface modification of graphene nanoplatelets (GNP) towards preparation of natural/synthetic rubber blend nanocomposites -- Mechanical properties of nanoclay composite materials -- Fireproof capability of rigid polyurethane foam based composite materials -- Structural behavior of composite materials in fire -- Natural resources based green composite materials -- Composite materials for wind turbine structure -- Electrochromic Smart Windows: An Energy-efficient Technology -- Graphitic Carbon Nitride/ Metal Oxides Nanocomposites and Their Applications in Engineering -- Application of Nanofiber-based Composites: Progressive Health Impact -- Polymer-based Nanocomposite: Recent Trends in Safety Assessments in biomedical applications -- Modern approach of hydroxyapatite based composites for biomedical applications -- Hybrid Composite in Orthopedic applications -- Polymer-based composite in biomedical applications -- Components of All-solid-state Ion-Selective Electrodes (AS-ISEs) -- Nanocellulose and Nanocellulose-based Composites for Food Applications -- Nanocomposite Materials in Food Packaging: Opportunities, Challenges and Safety Assessment -- Biodegradability and Composite Coatings: Past, Present and Future Prospects -- Nanocomposite Film for Food Packaging: Opening Doors to Future Applications -- Functional Chitosan-Based Composites for Potential Application in Food Industry -- Metal-insulator-metal as a biosensing platfrom .
    Abstract: Composite materials are formed when the combination of separate materials acquire new properties distinct from its components. They have a range of applications in fields such as mechanical and electrical engineering, food science and biomedicine and represent a fast-growing area of research. Composite Materials: Applications in Engineering, Biomedicine and Food Science provides an overview of current technologies and applications related to composite materials in these fields. Organized by discipline, the text encompasses a wide variety of composite materials, including polymer, ceramic, biomaterial, hydroxyapatite, nanofiber and green composites. Early chapters detail the enhanced mechanical, magnetic, dielectric properties of electrical and thermal conductive composite materials, which are essential in daily science. Subsequent chapters focus on filler or reinforcement materials, including carbon materials, hybrid materials and nanomaterials. Particular emphasis is placed on nanocomposite materials, as these have increasingly diverse field applications. Various manufacturing methods, such as the synthesis method and top-down/bottom-up manufacturing, are also discussed. Coverage of the recent progress, challenges and opportunities surrounding composite materials make this text a one-stop reference for engineers, scientists and researchers working in this exciting field.
    Type of Medium: Online Resource
    Pages: XI, 484 p. 213 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030454890
    URL: https://doi.org/10.1007/978-3-030-45489-0
    DOI: 10.1007/978-3-030-45489-0
    DDC: 660.6
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    Wetland Plants : A Source of Nutrition and Ethno-medicines (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Nutrition   . ; Medicinal chemistry. ; Food science. ; Plant Science. ; Nutrition. ; Medicinal Chemistry. ; Food Science.
    Description / Table of Contents: Foreword -- Preface -- Wetlands and Wetland Plants -- Climate of Wetlands -- Types of Wetlands and Wetland Plants -- Importance of Biodiversity in Wetlands -- Nutritive Value of Wetland Flora -- Medicinally Important Wetland Flora -- Threats to Biodiversity of Wetlands -- Conservation Strategies of Wetland Flora -- Wetland Plants of Himalayas: A case study -- A Pictorial Guide to Wetland plants of Himalayas -- Bibliography.
    Abstract: Due to their high nutritive value and the presence of secondary metabolites, wetland plants can be consumed by humans as food and utilized as medicinal drugs. Significant numbers of ethno-botanic resources have been reported to extract useful compounds, which can be used as pharmaceuticals. Wetland plants are also very valuable as an energy source, as fuel for fish smoking and for domestic energy. These plants can be harvested as wild stock, or cultivated in flooded paddies for aquaculture, food and for livestock fodder. All parts of plants can be utilized for foodstuff, compost, mulch, medicine, and for construction. Wetland Plants: A Source of Nutrition and Ethnomedicine aims to promote public understanding of this remarkable resource, exploring not only their role in the ecosystem but also their nutritional and medicinal purposes. Based on original research, the text focuses on species identification (with original pictures of wetland plants including morphological features), nutritive value and ethno-medicinal uses. This book serves as an important and basic reference material for further research into the basic biological as well as the applied medicinal aspects of traditional medicinal wetland plants.
    Type of Medium: Online Resource
    Pages: XXIX, 228 p. 149 illus., 148 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030692582
    URL: https://doi.org/10.1007/978-3-030-69258-2
    DOI: 10.1007/978-3-030-69258-2
    DDC: 580
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    Mathematical Models for Dental Materials Research (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Biomaterials. ; Mathematical models. ; Dentistry. ; Biomedical engineering. ; Biotechnology. ; Biomaterials. ; Mathematical Modeling and Industrial Mathematics. ; Dentistry. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1 - Systematic Errors in Longitudinal Measurements -- Chapter 2 - Endodontic Treatment and Vertical Root Fracture -- Chapter 3 - Debonding of Resin Composite Restorations -- Chapter 4 - Attenuation of Curing Light through Resin Composite Restorations -- Chapter 5 - Release of Ions or Molecules from Dental Restorations -- Chapter 6 - Heat Generated from Dental Resin Composites during Curing -- Chapter 7 - Mechanical Failure of Dental Restorations – The Weakest-Link Theory -- Chapter 8 - Stability of Dental Implants -- Chapter 9 - Kinetics of Photo-polymerization -- Index.
    Abstract: This book presents a mechanistic approach—mathematical modeling—for carrying out dental materials research. This approach allows researchers to go beyond the null hypothesis and obtain a solution that is more general and therefore predictive for conditions other than those considered in a study. Hence it can be used either on its own or to complement the commonly used statistical approach. Through a series of practical problems with wide-ranging application, the reader will be guided on: How to construct a mathematical model for the behavior of dental materials by making informed assumptions of the physical, chemical, or mechanical situation How to simplify the model by making suitable simplifications How to calibrate the model by calculating the values of key parameters using experimental results How to refine the model when there are discrepancies between predictions and experiments Only elementary calculus is required to follow the examples and all the problems can be solved by using MS Excel© spreadsheets. This is an ideal book for dental materials researchers without a strong mathematical background who are interested in applying a more mechanistic approach to their research to give deeper insight into the problem at hand. Advance praise for Mathematical Models for Dental Materials Research: “This is a nice addition for research students on how to conduct their work and how to manage data analysis. It brings together a number of important aspects of dental materials investigations which has been missing in the literature. The practical examples make it much easier to understand.” – Michael F. Burrow, Clinical Professor in Prosthodontics, The University of Hong Kong “The great strengths of this volume are the real world examples of dental materials research in the successive chapters. In turn, this is an outcome of the outstanding expertise of both authors. I warmly recommend this book to the dental biomaterials community worldwide.” – David C. Watts, Professor of Biomaterials Science, University of Manchester, UK.
    Type of Medium: Online Resource
    Pages: XIV, 77 p. 41 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030378493
    URL: https://doi.org/10.1007/978-3-030-37849-3
    DOI: 10.1007/978-3-030-37849-3
    DDC: 660.6
    Language: English
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    Brassica Improvement : Molecular, Genetics and Genomic Perspectives (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Agriculture. ; Plant biotechnology. ; Plant physiology. ; Plant genetics. ; Nutrition   . ; Agriculture. ; Plant Biotechnology. ; Plant Physiology. ; Plant Genetics. ; Nutrition.
    Description / Table of Contents: 1 Utilization of rapeseed-mustard genetic resources for Brassica improvement -- 2 Recent advances in cytoplasmic male sterility (CMS) in crop Brassicas -- 3 Ancient and recent Polyploid evolution in Brassicas -- 4 Production and application of doubled haploid in Brassica improvement.-5 Tissue culture-mediated biotechnological advancements in genus Brassica -- 6 Genomics for Brassica quality improvement -- 7 Biofortification of Brassica for quality improvement.-8 Genetics and Genomic Approaches for Disease Resistance in Brassicas.-9 Arsenic toxicity and molecular mechanism of arsenic tolerance in different members of Brassicaceae.-10 Transgenic approaches for Brassica improvement.-11 Genetic diversity studies in Indian mustard using molecular markers.
    Abstract: Global population is mounting at an alarming stride to surpass 9.3 billion by 2050, whereas simultaneously the agricultural productivity is gravely affected by climate changes resulting in increased biotic and abiotic stresses. The genus Brassica belongs to the mustard family whose members are known as cruciferous vegetables, cabbages or mustard plants. Rapeseed-mustard is world’s third most important source of edible oil after soybean and oil palm. It has worldwide acceptance owing to its rare combination of health promoting factors. It has very low levels of saturated fatty acids which make it the healthiest edible oil that is commonly available. Apart from this, it is rich in antioxidants by virtue of tocopherols and phytosterols presence in the oil. The high omega 3 content reduces the risk of atherosclerosis/heart attack. Conventional breeding methods have met with limited success in Brassica because yield and stress resilience are polygenic traits and are greatly influenced by environment. Therefore, it is imperative to accelerate the efforts to unravel the biochemical, physiological and molecular mechanisms underlying yield, quality and tolerance towards biotic and abiotic stresses in Brassica. To exploit its fullest potential, systematic efforts are needed to unlock the genetic information for new germplasms that tolerate initial and terminal state heat coupled with moisture stress. For instance, wild relatives may be exploited in developing introgressed and resynthesized lines with desirable attributes. Exploitation of heterosis is another important area which can be achieved by introducing transgenics to raise stable CMS lines. Doubled haploid breeding and marker assisted selection should be employed along with conventional breeding. Breeding programmes aim at enhancing resource use efficiency, especially nutrient and water as well as adoption to aberrant environmental changes should also be considered. Biotechnological interventions are essential for altering the biosynthetic pathways for developing high oleic and low linolenic lines. Accordingly, tools such as microspore and ovule culture, embryo rescue, isolation of trait specific genes especially for aphid, Sclerotinia and alternaria blight resistance, etc. along with identification of potential lines based on genetic diversity can assist ongoing breeding programmes. In this book, we highlight the recent molecular, genetic and genomic interventions made to achieve crop improvement in terms of yield increase, quality and stress tolerance in Brassica, with a special emphasis in Rapeseed-mustard.
    Type of Medium: Online Resource
    Pages: XIII, 253 p. 11 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030346942
    URL: https://doi.org/10.1007/978-3-030-34694-2
    DOI: 10.1007/978-3-030-34694-2
    DDC: 630
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    Online Resource
    Changing Climate, Changing Worlds : Local Knowledge and the Challenges of Social and Ecological Change (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Plants Evolution. ; Climatology. ; Biodiversity. ; Plant ecology. ; Anthropology. ; Plant Evolution. ; Climate Sciences. ; Biodiversity. ; Plant Ecology. ; Anthropology.
    Description / Table of Contents: Foreword -- Introduction -- Global change through an indigenous lens -- People, water, fish and plants -- Pathways to bring ethnobiological contributions to climate change research -- Who’s climate? Who’s change? Various views from rural Northern Cameroon -- Indigenous Tea Farmers’ Responses and Adaptations to Climate Change -- Observing wild flora to understand local perceptions of climate change in a temperate rural area -- Understanding Climate Change and Planning for the Future in Southern Appalachia -- Rains and men -- The year people and wild animals got closer -- Understanding how pastoralists perceive environmental, including climate, changes and ideas for solutions -- Conclusions -- Index.
    Abstract: This book explores how individuals and communities perceive and understand climate change using their observations of change in the world around them. Because processes of climatic change operate at spatial and temporal scales that differ from those of everyday practice, the phenomenon can be difficult to understand. However, flora and fauna, which are important natural and cultural resources for human communities, do respond to the pressures of environmental change. Humans, in turn, observe and adapt to those responses, even when they may not understand their causes. Much of the discussion about human experiences of our changing climate centers on disasters and extreme events, but we argue that a focus on the everyday, on the microexperiences of change, has the advantage of revealing how people see, feel, and make sense of climate change in their own lives. The chapters of this book are drawn from Asia, Europe, Africa, and South and North America. They use ethnographic inquiry to understand local knowledge and perceptions of climate change and the social and ecological changes inextricably intertwined with it. Together, they illustrate the complex process of coming to know climate change, show some of the many ways that climate change and our responses to it inflict violence, and point to promising avenues for moving toward just and authentic collaborative responses.
    Type of Medium: Online Resource
    Pages: X, 266 p. 64 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030373122
    Series Statement: Ethnobiology,
    URL: https://doi.org/10.1007/978-3-030-37312-2
    DOI: 10.1007/978-3-030-37312-2
    DDC: 581.38
    Language: English
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    Online Resource
    Online Resource
    Salivary Bioscience : Foundations of Interdisciplinary Saliva Research and Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Biochemistry. ; Psychology. ; Dentistry. ; Endocrinology. ; Biomedical Research. ; Medical Biochemistry. ; Biochemistry. ; Behavioral Sciences and Psychology. ; Dentistry. ; Endocrinology.
    Description / Table of Contents: Part 1: What is Salivary Bioscience, Why is it Important, and How Do We Study It? -- Chapter 1: Foundations of Interdisciplinary Salivary Bioscience: An Introduction (Granger et al.) -- Chapter 2: Salivary Gland Anatomy and Physiology (Hernández et al.) -- Chapter 3: Saliva Collection, Handing, Transport, and Storage: Special Considerations and Best Practices for Interdisciplinary Salivary Bioscience(Padilla et al.) -- Chapter 4: Analytical Strategies and Tactics in Salivary Bioscience (Riis et al.) -- Part 2: Physiology and Development Research and Applications (Part 2 Editor: Dr. Jenna Riis) -- Chapter 5: Salivary Bioscience, Human Stress, and the Hypothalamic Pituitary Adrenal Axis (Clow et al.) -- Chapter 6: The Use of Saliva for Genetics and Epigenetics Research (Nemoda et al.) -- Chapter 7: Saliva as a Window Into the Human Oral Microbiome and Metabolome(Whiteson et al.) -- Chapter 8: Salivaomics, saliva Exo-somics, and Saliva Liquid Biopsy (Wong et al.) -- Chapter 9: Salivary Bioscience, Immunity, and Inflammation (Riis et al.) -- Chapter 10:Salivary Bioscience and Human Development (Hibel et al.) -- Part 3: Biomedical Research and Related Applications (Part 3 Editor: Dr. Elizabeth Thomas) -- Chapter 11: Biomedical Research and Related Applications:Current Assay Methods and Quality Requirements in Oral Fluid Diagnostics Applications (Granger S. et al.) -- Chapter 12: Salivary Biomarkers and Neurodegenerative Conditions (Thomas et al.) -- Chapter 13: The Use of Antibodies in Saliva to Measure PathogenExposure and Infection(Heaney et al.) -- Chapter 14: Salivary Bioscience and Pain (Payne et al.) -- Chapter 15: Salivary Bioscience and Environmental Exposure Assessment (Panuwet et al.) -- Chapter 16: Saliva and Drugs of Abuse (Navazesh et al.) -- Chapter 17: Therapeutic Drug Monitoring in Saliva (Thomas) -- Chapter 18: Salivary Bioscience and Periodontal Medicine (Freire et al.) -- Chapter 19: Salivary Bioscience and Cancer (Navazesh et al.) -- Part 4: Psychosocial Research and Applications(Part 4 Editor: Dr. Kate Ryan Kuhlman) -- Chapter 20: Salivary Bioscience in Clinical Psychologyand Psychiatry(Kuhlman) -- Chapter 21: Salivary Bioscience Research in Health Psychology and Behavioral Medicine (Hoyt et al.) -- chapter 22: The Neuroscience of Human Social Behavior: A Review of How Testosterone and Cortisol Underpin Competition and Affiliation Dynamics (Kornienko et al.) -- chapter 23: Salivary Studies of the Social Neuroscience of Human-animal Interaction (Pendry et al.) -- Part 5: Population Health Research and Applications(Part 5 Editor: Dr. Marcus Taylor) -- Chapter 24: Salivary Bioscience and Military, Space, and OperationalResearch(Roma et al.) -- Chapter 25: Salivary Bioscience Research Related to Prenatal Adversity (Eiden et al.) -- Chapter 26: Salivary Bioscience and Pediatrics (Johnson et al.) -- Chapter 27: Use of saliva to better understand the experience of adulthood and aging(Almeida et al.) -- Chapter 28: Salivary Bioscience and Research on Animal Welfare and Conservation Science(Staley et al.) -- Part 6: The Way Forward: Future Directions for the Science and Practice of Salivary Bioscience -- Chapter 29:Applications of Salivary Bioscience to Precision Medicine (Kuhlman) -- Chapter 30:Public Health and IndustryApplications of Salivary Bioscience (Riis et al.) -- Chapter 31: Envisioning the Future of Interdisciplinary Salivary Bioscience (Granger et al.).
    Abstract: This book provides the first comprehensive overview of the emerging field of interdisciplinary salivary bioscience. It serves as a foundational reference guide to the collection, analysis, and interpretation of salivary data, as well as its myriad applications in medicine, surveillance and public health. The ease and non-invasive nature of saliva collection makes it highly useful in diverse fields such as pediatrics, dentistry, neuroscience, psychology, animal welfare and precision medicine. This book introduces students and scientists alike to the vast potential of salivary bioscience in both research and practice.
    Type of Medium: Online Resource
    Pages: XIV, 751 p. 56 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357849
    URL: https://doi.org/10.1007/978-3-030-35784-9
    DOI: 10.1007/978-3-030-35784-9
    DDC: 610.72
    Language: English
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