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  • Q1-390  (1.522)
  • bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general  (1.134)
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-03-07
    Beschreibung: This reprint is the printed edition of the Special Issue published in Materials. The reprint provides an overview on current international research activities in the field of advanced pulse laser machining technology. It covers fundamental and applied aspects and collects contributions of renowned scientists from academics and industries working in the fields of laser processing, materials science, physics, chemistry, and engineering in order to foster the current knowledge and present new ideas for future applications and new technologies.
    Schlagwort(e): multi-beam micromachining ; beam splitting ; invar ; shadow masks ; OLED ; nanosecond laser ; direct laser interference patterning ; design of experiments ; central composite design ; morphological filtering ; surface texture homogeneity ; micro structuring ; bearing steel ; dual laser beam processing ; excited state absorption ; semiconducting thin films ; stimulated emission depletion ; femtosecond laser ; silicon ; amorphization ; crystallization ; spectroscopic imaging ellipsometry ; transmission electron microscopy ; atomic force microscopy ; laser ablation ; ultrafast ; re-deposition ; fs-laser writing ; waveguides ; element redistribution ; Soret effect ; diffusion competition effects ; ultra-short pulses ; double pulses ; burst processing ; MHz bursts ; GHz bursts ; X-ray emission ; micromachining ; dose rate ; X-ray spectrum ; ultrafast laser ; laser ; ultrashort pulse ; plasma ; X-ray ; Bremsstrahlung ; resonance absorption ; burst ; bi-burst ; beam shaping ; squared top-hat ; fs-laser ; laser surface structuring ; laser-induced periodic surface structures ; micro-channels ; glass ; ultrafast laser processing ; Bessel beam ; X-ray emission hazards ; ultrashort pulsed laser ; radiation protection ; industrial applications ; protection housing ; ambient dose rate ; pulsed laser ; laser micromachining ; mechanical shutter ; solenoid shutter ; electro-optic modulator shutter ; opening time ; lifetime ; X-ray energies ; X-ray dose rate ; laser printing ; laser-induced forward transfer (LIFT) ; digital manufacturing ; additive manufacturing ; printing of materials ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
    Sprache: Englisch
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  • 2
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-01-08
    Beschreibung: Global warming is imposing tremendous challenges upon human and otherwise biotic life on Earth. A warmer atmosphere holds more moisture. The consensus is that the moisture transport by the atmospheric circulation strengthens and makes already wet areas of moisture convergence wetter and already dry areas of moisture divergence drier. Therefore, the tropics and mid-to-high latitudes will get wetter and the subtropics will get drier. Without any change in the interannual variability of hydroclimate, the change in the mean hydroclimate would equally increase drought risk in some places and flood risk in others. Moreover, global warming will cause the interannual variability of the hydroclimate to intensify, which will induce more droughts and floods. Furthermore, the changing atmospheric circulation interaction with the land surface may cause storm track alterations and may play an important role in shaping moisture redistribution. The author's contributions have documented the precipitation trends in southeast of the US, the Nile River Basin Ethiopia, Iraq, the Huai River Basin of northern China, and the Qilian Mountains of western China. The precipitation predictability on both global and regional scales are also studied. The interaction among climate systems in southeast Asia is also explicitly documented.
    Schlagwort(e): El Niño ; winter weather types ; precipitable water ; surface water vapor pressure ; consistency ; interannual and long-term trend ; precipitation ; trend analysis ; Iraq ; climate projection ; CMIP5 ; groundwater levels ; rainfall ; temperature ; Mann–Kendall test ; Bayesian Ensemble Algorithm ; rainstorm process ; rainstorm intensity ; risk estimation and mapping ; CMIP6 ; risk prediction ; Southwest China ; rainstorm and flood ; spatial and temporal change ; atmospheric circulation ; rainfall change ; CHIRPS ; PERSIANN-CDR ; descriptive statistics ; non-parametric trends ; Google Earth Engine ; central Punjab ; climate change ; land cover/land use ; vegetation ; NDVI ; Huai River Basin ; trends and variability ; flood magnitude ; Qilian Mountains ; cyclones power dissipation index (PDI) ; monsoon trough ; El Niño southern oscillation (ENSO) ; Indian Ocean dipole (IOD) ; Walker circulation ; predictability ; global ; seasonal precipitation ; ENSO ; MJO ; climate trend ; land use land cover ; Nile River Basin ; water resources ; raindrop spectrum ; radar ; dynamic Z-I ; LSTM neural network ; precipitation estimation ; Loess Plateau ; spring maize ; relative soil moisture ; drought index ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RB Earth sciences::RBP Meteorology & climatology
    Sprache: Englisch
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  • 3
    Publikationsdatum: 2024-04-05
    Beschreibung: After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.
    Schlagwort(e): QD1-999 ; Q1-390 ; Nanoparticles ; Gene Therapy ; Immunotherapy ; bioimaging ; theranostics ; nanomaterials ; Drug delivery ; Nanomedicine ; Cancer ; Phototherapy ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Sprache: Englisch
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-09-11
    Beschreibung: Landscapes and cultural heritage have faced many challenges over time, including modifications and degradation that appear with time, overlaps with other challenges not previously observed, and the influence of cities and management. One of the most visible and globally discussed challenges is climate change. Therefore, there is an urgent need to launch initiatives to tackle climate change and other current challenges from the perspective of landscape and cultural heritage protection. This Special Issue presents selected papers of studies conducted in relation to the 28th Conference on the Series of Garden Art and Historical Dendrology entitled “Climate Change and Current Challenges for Landscapes and Cultural Heritage” that was held on 28 and 29 October 2021. This collection serves as a platform for the exchange of experiences among researchers from different scientific domains.
    Schlagwort(e): nature reserves ; landscape fragmentation ; north–south transitional zone ; spatial differentiation ; Qinling–Daba Mountains ; habitat quality ; water dams ; Krakow fortress ; climate change ; environmental management ; cultural heritage conservation ; urban densification ; prefabricated housing estates ; spatial devastation ; protection of urban layout ; Cracow ; climate change mitigation ; cultural heritage ; urban renewal ; urban parks ; therapeutic landscapes ; climate resilience ; vernacular heritage ; climate narratives ; climate adaptation ; climate stories ; courtyard ; urban green infrastructure ; urban pattern ; supervised classification ; ecosystem services (ES) ; urban cemeteries ; biocultural diversity (BCD) ; urban green infrastructure (UGI) ; questionnaire survey ; Leipzig ; Łódź ; sensory gardens ; urban green spaces ; aromatic herbs ; plant smell memory ; stress ; human wellbeing in urban areas ; restorative environments ; history of gardens ; castle garden ; goosefoot avenue ; star-shaped garden layout ; Austro-Hungarian Empire ; Transylvania as part of Romania ; green infrastructure ; resilience management ; biodiversity ; scenario analysis ; cellular automata model ; historic psychiatric hospitals ; therapeutic landscape ; green therapy ; horticulture therapy ; historical commons ; human cultural heritage ; local development ; landscape values ; rainwater management ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Sprache: Englisch
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-20
    Beschreibung: Anthropogenic greenhouse gas (GHG) emissions are dramatically influencing the environment, and research is strongly committed to proposing alternatives, mainly based on renewable energy sources. Low GHG electricity production from renewables is well established but issues of grid balancing are limiting their application. Energy storage is a key topic for the further deployment of renewable energy production. Besides batteries and other types of electrical storage, electrofuels and bioderived fuels may offer suitable alternatives in some specific scenarios. This Special Issue includes contributions on the energy conversion technologies and use, energy storage, technologies integration, e-fuels, and pilot and large-scale applications.
    Schlagwort(e): Q1-390 ; QC1-999 ; n/a ; PV ; GHG savings ; lithium-ion battery (LIB) ; probability prediction ; decarbonization ; supercapacitor (SC) ; least squares support vector machine ; EV fleet forecasts ; alternative maritime power (AMP) ; Markov chain ; feasibility study ; D funding ; hybrid power system ; numerical analysis ; ship structure ; optimal sizing ; cellulosic ethanol ; electric vehicles EV ; biofuel ; green ship ; R&amp ; bulk carrier ; molten carbonate fuel cell system ; sparse Gaussian process regression ; power-to-gas ; combination method ; charging infrastructure ; jet fuel ; flow characteristics ; hybrid refinery ; LNG-fueled ship ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Englisch
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  • 6
    Publikationsdatum: 2024-04-11
    Beschreibung: It has become more evident that many microalgae respond very differently than land plants to diverse stimuli. Therefore, we cannot reduce microalgae biology to what we have learned from land plants biology. However, we are still at the beginning of a comprehensive understanding of microalgae biology. Microalgae have been posited several times as prime candidates for the development of sustainable energy platforms, making thus the in-depth understanding of their biological features an important objective. Thus, the knowledge related to the basics of microalgae biology must be acquired and shared rapidly, fostering the development of potential applications. Microalgae biology has been studied for more than forty years now and more intensely since the 1970’s, when genetics and molecular biology approaches were integrated into the research programs. Recently, studies on the molecular physiology of microalgae have provided evidences on the particularities of these organisms, mainly in model species, such as Chlamydomonas reinhardtii. Of note, cellular responses in microalgae produce very interesting phenotypes, such as high lipid content in nitrogen deprived cells, increased protein content in cells under high CO2 concentrations, the modification of flagella structure and motility in basal body mutant strains, the different ancient proteins that microalgae uses to dissipate the harmful excess of light energy, the hydrogen production in cells under sulfur deprivation, to mention just a few. Moreover, several research groups are using high-throughput and data-driven technologies, including “omics” approaches to investigate microalgae cellular responses at a system-wide level, revealing new features of microalgae biology, highlighting differences between microalgae and land plants. It has been amazing to observe the efforts towards the development and optimization of new technologies required for the proper study of microalgae, including methods that opened new paths to the investigation of important processes such as regulatory mechanisms, signaling crosstalk, chemotactic mechanisms, light responses, chloroplast controlled mechanisms, among others. This is an exciting moment in microalgae research when novel data are been produced and applied by research groups from different areas, such as bioprocesses and biotechnology. Moreover, there has been an increased amount of research groups focused in the study of microalgae as a sustainable source for bioremediation, synthesis of bioproducts and development of bioenergy. Innovative strategies are combining the knowledge of basic sciences on microalgae into their applied processes, resulting in the progression of many applications that hopefully, will achieve the necessary degree of optimization for economically feasible large-scale applications. Advances on the areas of basic microalgae biology and novelties on the essential cellular processes were revealed. Progress in the applied science showed the use of the basic science knowledge into fostering translational research, proposing novel strategies for a sustainable world scenario. In this present e-book, articles presented by research groups from different scientific areas showed, successfully, the increased development of the microalgae research. Herewith, you will find articles ranging from bioprospecting regional microalgae species, through advances in microalgae molecular physiology to the development of techniques for characterization of biomass and the use of biomass into agriculture and bioenergy production. This e-book is an excellent source of knowledge for those working with microalgae basic and applied sciences, and a great opportunity for researchers from both areas to have an overview of the amazing possibilities we have for building an environmentally sustainable future once the knowledge is translated into novel applications.
    Schlagwort(e): TA1-2040 ; TP248.13-248.65 ; QK1-989 ; Q1-390 ; Biotechnology ; biomass ; Hydrogen ; bioenergy ; Nutrients ; Lipids ; Microalgae ; Biofuels ; sustainability ; Carbon Dioxide ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Sprache: Englisch
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-05-06
    Beschreibung: Wildfire risk can be perceived as the combination of wildfire hazards (often described by likelihood and intensity) with the susceptibility of people, property, or other valued resources to that hazard. Reflecting the seriousness of wildfire risk to communities around the world, substantial resources are devoted to assessing wildfire hazards and risks. Wildfire hazard and risk assessments are conducted at a wide range of scales, from localized to nationwide, and are often intended to communicate and support decision making about risks, including the prioritization of scarce resources. Improvements in the underlying science of wildfire hazard and risk assessment and in the development, communication, and application of these assessments support effective decisions made on all aspects of societal adaptations to wildfire, including decisions about the prevention, mitigation, and suppression of wildfire risks. To support such efforts, this Special Issue of the journal Fire compiles articles on the understanding, modeling, and addressing of wildfire risks to homes, water resources, firefighters, and landscapes.
    Schlagwort(e): wildfire risk ; object-oriented image analysis ; Sentinel-2 ; fire behavior ; flammap ; wildfire management ; water supply ; erosion ; wildfire containment ; Potential fire Operational Delineations ; Monte Carlo simulation ; transmission risk ; WUI ; fire ; defensible space ; prescribed fire ; community vulnerability ; fire suppression costs ; Zillow ; wildfire ; predictive modeling ; fire spread model ; Monte Carlo ; spatial modeling ; area difference index ; statistics ; precision ; recall ; principal components analysis ; risk assessment ; structure loss ; wildland–urban interface ; mitigation ; mapping ; land use ; disaster ; fire spread models ; surrogate modeling ; sensitivity analysis ; global sensitivity analysis ; colour coding ; communication ; forest fire ; ordinal categorization ; palette ; risk ; firefighter safety ; safe separation distance ; safety zones ; LCES ; Google Earth Engine ; lidar ; LANDFIRE ; Landsat ; GEDI ; parcel-level risk ; post-fire analysis ; risk mitigation ; rapid assessment ; natural hazards ; fuels ; fire hazard ; remote sensing ; LiDAR ; Sentinel ; modeling ; simulation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
    Sprache: Englisch
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-01-05
    Beschreibung: The purpose of this Special Issue was to collect and present research results and experiences on energy supply in the Visegrad Group countries. This research considers both macroeconomic and microeconomic aspects. It was important to determine how the V4 countries deal with energy management, how they have undergone or are undergoing energy transformation and in what direction they are heading. The articles concerned aspects of the energy balance in the V4 countries compared to the EU, including the production of renewable energy, as well as changes in its individual sectors (transport and food production). The energy efficiency of low-emission vehicles in public transport and goods deliveries are also discussed, as well as the energy efficiency of farms and energy storage facilities and the impact of the energy sector on the quality of the environment.
    Schlagwort(e): energy supplies ; energy security ; energy market ; EU countries ; Hellwig’s method ; sustainability strategies ; sustainable development ; Visegrád Group ; sustainable strategic management ; the renewable energy sector ; energy use ; structures ; food production systems ; Visegrad Group ; energy mix ; renewables ; energy in transport ; energetic efficiency ; energy sources ; economic growth ; developing and developed countries ; energy sector ; environmental quality ; renewable energy sources (RES) ; nuclear energy ; southeastern Poland ; sustainability ; renewable energy sources ; European Union ; cluster analysis ; Visegrad Group countries ; fuels ; cointegration ; Granger causality ; electricity prices ; households ; directions of price changes ; biogas energy ; solar energy ; hybrid biogas plant ; renewable energy ; circular economy ; off-grid systems ; energy efficiency ; social and economic aspects of energy ; economic efficiency ; low emissions ; zero emissions ; e-commerce ; last mile ; parcel lockers ; efficiency of logistics processes ; economies of scale ; simulation of logistics processes ; COVID-19 ; BESS management ; price arbitration ; shift load ; microgrid ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
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  • 9
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: Die Arbeit besteht somit aus zwei Hauptteilen. Zunächst werden in den "Vorbemerkungen" die wichtigsten Begriffe gegeneinander abgegrenzt und ein Forschungsüberblick gegeben. Da die Entwicklung der russischen Sprache eng mit den jeweiligen geschichtlichen Ereignissen verknüpft ist, werden im ersten, mehr referierenden Teil die geschichtlichen Voraussetzungen für den Sprachwandel in einem kurzen Überblick dargelegt. Anschließend wird die sprachliche Umbruchsituation charakterisiert. Einen eigenen Abschnitt wird dabei die Einordnung des "Artakserksovo dejstvo" in den literarischen Kontext seiner Zeit bilden. Im zweiten Teil wird der Text des "Artakserksovo dejstvo" sprachlich untersucht.
    Schlagwort(e): Artakserksovo ; ausgehenden ; dejstvo ; Jahrhunderts ; Rußland ; Schellenberger ; Situation ; Sprache ; sprachlichen ; Studien ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 10
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: The aim of this work is to integrate the West Slavic languages ​​into grammar and language comparisons using modern grammatical approaches. This is done using the example of the imperative sentence in Slovak with a view to other West Slavic languages. This type of sentence is examined for its formal and content-related characteristics. At the same time, its communicative-pragmatic potential is derived and explained from the structural meaning of this mode verbi. The demarcation between the grammar and the pragmatics of the imperative theorem will play an important role here.
    Beschreibung: Das Ziel dieser Arbeit ist es, die westslawischen Sprachen unter Anwendung moderner grammatiktheoretischer Ansätze in den Grammatik- und Sprachvergleich zu integrieren. Dies erfolgt am Beispiel des Imperativsatzes im Slowakischen mit Blick auf andere westslawische Sprachen. Dieser Satztyp wird hinsichtlich seiner formalen und inhaltlichen Eigenschaften untersucht. Zugleich wird sein kommunikativ-pragmatisches Potential aus der Strukturbedeutung dieses Modus verbi abgeleitet und erklärt. Dabei wird die Grenzziehung zwischen der Grammatik und der Pragmatik des Imperativsatzes eine wichtige Rolle spielen.
    Schlagwort(e): Blick ; Grammatik ; grammatiktheoretisch ; Imperativsatz ; Linguistik ; Pragmatik ; Satztyps ; Semantik ; Slavische Sprachwissenschaft ; Slowakischen ; Späth ; Sprachen ; Strukturbedeutung ; Syntax ; westslawische ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 11
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    Firenze University Press
    Publikationsdatum: 2024-03-24
    Beschreibung: In light of the dramatic events which have been shocking Ukraine since November 2013, this work’s itinerary aims at functioning as a basis for the formulation of new contact points, for a dialogue between traditions and cultures which nowadays are again being shaken by the events of history. The author examines the self-identification paths of the literary phenomenon of Russian language in Ukraine. With the help of interviews with important representatives of the Ukrainian Russian-speaking literary scene, made on the eve of the so-called 'Ukrainian crisis', the author shall closely observe the origins of the marginal nature of these 'post-Soviet hybrid narratives'.
    Schlagwort(e): thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Sprache: Italienisch
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  • 12
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: In the past two decades there have been significant advances made in understanding the cellular and molecular alterations that occur with brain ageing, as well as with our understanding of age-related brain diseases. Ageing is associated with a mid-life decline in many cognitive domains (eg. Attention, working memory, episodic memory) that progresses with advancing age and which may be potentiated by a variety of diseases. However, despite the breadth of attempts to explain it, the underlying basis for age-related memory impairment remains poorly understood. Both normal and “pathological” ageing (as in age-related neurodegenerative disorders such as Alzheimer’s disease) may be associated with overlapping and increased levels of “abnormal” pathology, and this may be a potential mediator of cognitive decline in both populations. An emerging hypothesis in this field is that metal ion dys/homeostasis may represent a primary unifying mechanism to explain age- and disease-associated memory impairment – either indirectly via an effect on disease pathogenesis, or by a direct effect on signaling pathways relevant to learning and memory. There remains a concerted worldwide effort to deliver an effective therapeutic treatment for cognitive decline associated with ageing and/or disease, which is currently an unmet need. There have been numerous clinical trials conducted specifically testing drugs to prevent cognitive decline and progression to dementia, but to date the results have been less than impressive, highlighting the urgent need for a greater understanding of the neurobiological basis of memory impairment in ageing and disease which can then drive the search for effective therapeutics.
    Schlagwort(e): RC321-571 ; Q1-390 ; Down Syndrome ; Amyotrophic Lateral Sclerosis ; Parkinson's disease ; aluminium ; Iron ; TBI ; Cognition ; Copper ; Alzheimer's disease ; Zinc ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 13
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: 〈P〉The authors of the articles are Slovak linguists who work within various spheres of linguistics. Represented in the volume are authors who started their scientific activity in the pre-war period, directly or indirectly building on the work of the Prague Linguistic Circle, but soon differentiating themselves and contributing to linguistic theory with original works, as well as a newer generation of linguists who entered linguistics within the last two decades. 〈/P〉
    Schlagwort(e): Kacala ; Linguistics ; Linguistik ; Prague Linguistic Circle ; pre-war period ; Reader ; Semantics ; Slavische Sprachwissenschaft ; Slovak ; Slovak linguists ; Studies ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 14
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: 〈P〉Die 1972 von den Frankfurter Slavisten Olexa Horbatsch und Gerd Freidhof begründete Reihe Specimina philologiae Slavicae wird heute von Holger Kuße (Dresden), Peter Kosta (Potsdam), Beatrix Kreß (Hildesheim), Franz Schindler (Gießen), Barbara Sonnenhauser (Zürich) und Nadine Thielemann (Wien) herausgeben. In der Reihe erscheinen Monographien, Sammelbände und Lehrbücher zu allen Gebieten der Slavistik, der Sprach-, der Literatur- und der Kulturwissenschaft. In der Sprachwissenschaft erscheinen sowohl sprachhistorische als auch innovative Arbeiten zur Pragmatik und Semantik, zu slavischen Kleinsprachen und zur Diskurslinguistik. In der Literatur- und Kulturwissenschaft gehört zu den besonderen Interessensgebieten die Russische Philosophie.〈/P〉
    Schlagwort(e): České ; comparison ; Czech ; Degrees ; Linguistik ; Literatur ; Marvan ; Philologie ; Slawistik ; Sprachwissenschaft ; stupňování ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-02-20
    Beschreibung: This Special Issue, “Mapping Indigenous Knowledge in the Digital Age”, explores Indigenous engagement with geo-information in contemporary cartography. Indigenous mapping, incorporating performance, process, product, and positionality as well as tangible and intangible heritage, is speedily entering the domain of cartography, and digital technology is facilitating the engagement of communities in mapping their own locational stories, histories, cultural heritage, environmental, and political priorities. In this publication, multimodal and multisensory online maps combine the latest multimedia and telecommunications technology to examine data and support qualitative and quantitative research, as well as to present and store a wide range of temporal/spatial information and archival materials in innovative interactive storytelling formats. It will be of particular interest to researchers engaged in studies of global human and environmental connection in the age of evolving information technology.
    Schlagwort(e): transdisciplinary research ; knowledge dialog ; participatory mapping ; qualitative analysis ; community-based management ; Dawes ; allotment ; GIS ; map ; automation ; PLSS ; geographic information systems ; reservation ; indigenous ; Standing Rock ; community mapping ; learning community ; natural resources management ; Cyberatlas ; Native Americans ; first nations ; historic cartography ; toponymy ; Indigenous maps ; indigital ; undergraduate education ; native science ; Inuinnait ; Inuinnaqtun ; cybercartography ; digital return ; multi-media cartography ; digital heritage ; native guidance system ; Lençóis Maranhenses region ; Maranhão coast ; traditional communities ; Cybercartographic Atlas ; indigenous mappings ; decolonial cartography ; mythical spaces and indigenous orientations ; sky map ; collaborative work ; Pa Ipai ; Baja California ; Mexico ; mapping ; reconciliation ; art ; digital pedagogy ; reflexivity ; Cybercartography ; GIAMedia ; FOSS ; intercultural literacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Sprache: Englisch
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  • 16
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Neuromorphic engineering has just reached its 25th year as a discipline. In the first two decades neuromorphic engineers focused on building models of sensors, such as silicon cochleas and retinas, and building blocks such as silicon neurons and synapses. These designs have honed our skills in implementing sensors and neural networks in VLSI using analog and mixed mode circuits. Over the last decade the address event representation has been used to interface devices and computers from different designers and even different groups. This facility has been essential for our ability to combine sensors, neural networks, and actuators into neuromorphic systems. More recently, several big projects have emerged to build very large scale neuromorphic systems. The Telluride Neuromorphic Engineering Workshop (since 1994) and the CapoCaccia Cognitive Neuromorphic Engineering Workshop (since 2009) have been instrumental not only in creating a strongly connected research community, but also in introducing different groups to each other’s hardware. Many neuromorphic systems are first created at one of these workshops. With this special research topic, we showcase the state-of-the-art in neuromorphic systems.
    Schlagwort(e): RC321-571 ; Q1-390 ; neuromorphic engineering ; Learning ; Floating gate ; Neural Network ; spike-based ; event-based ; simulation ; dynamic vision sensor ; network ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 17
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Despite the importance of mathematics in our educational systems little is known about how abstract mathematical thinking emerges. Under the uniting thread of mathematical development, we hope to connect researchers from various backgrounds to provide an integrated view of abstract mathematical cognition. Much progress has been made in the last 20 years on how numeracy is acquired. Experimental psychology has brought to light the fact that numerical cognition stems from spatial cognition. The findings from neuroimaging and single cell recording experiments converge to show that numerical representations take place in the intraparietal sulcus. Further research has demonstrated that supplementary neural networks might be recruited to carry out subtasks; for example, the retrieval of arithmetic facts is done by the angular gyrus. Now that the neural networks in charge of basic mathematical cognition are identified, we can move onto the stage where we seek to understand how these basics skills are used to support the acquisition and use of abstract mathematical concepts.
    Schlagwort(e): RC321-571 ; Q1-390 ; Neuroimaging ; development ; numerosity ; gifted ; Mathematical Cognition ; algebra ; abstract ; Expertise ; Arithmetic ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 18
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    Language Science Press | Language Science Press
    Publikationsdatum: 2024-03-24
    Beschreibung: This book is about reconstructing the grammar of Proto-Bantu, the ancestral language at the origin of current-day Bantu languages. While Bantu is a low-level branch of Niger-Congo, the world’s biggest phylum, it is still Africa’s biggest language family. This edited volume attempts to retrieve the phonology, morphology and syntax used by the earliest Bantu speakers to communicate with each other, discusses methods to do so, and looks at issues raised by these academic endeavours. It is a collective effort involving a fine mix of junior and senior scholars representing several generations of expert historical-comparative Bantu research. It is the first systematic approach to Proto-Bantu grammar since Meeussen’s Bantu Grammatical Reconstructions (1967). Based on new bodies of evidence from the last five decades, most notably from northwestern Bantu languages, this book considerably transforms our understanding of Proto-Bantu grammar and offers new methodological approaches to Bantu grammatical reconstruction.
    Schlagwort(e): Language Arts & Disciplines ; Linguistics ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
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  • 19
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    Routledge
    Publikationsdatum: 2024-04-06
    Beschreibung: This collection advocates languages-based, translational research to be part of the partnerships and collaborations required to make sense of, and respond to, COVID-19 as one of the major global challenges of our time. Bringing together scholars and practitioners from a wide range of disciplines, this volume is bound by a common thread stressing the importance of linguistic sensitivity, (inter)cultural knowledge and translational mediation in the frontline response to COVID-19. Featuring contributors from around the world and reflecting on the language used to frame COVID-19 in diverse cultural contexts of the Global North and Global South, the book proposes that paying attention to the transmission of ideas, ideologies, narratives and history through processes of translation results in a broadening of social, cultural and medical understandings of COVID-19. Spanning nearly 20 signed and spoken languages, the volume argues that only in going beyond an Anglophone perspective can we better understand the cultural, social and political facets of the pandemic and, in turn, produce a comprehensive, efficient global response to disease management. This book will be of interest to scholars in translation and interpreting studies, modern languages, applied linguistics, cultural studies, Deaf Studies, intercultural communication and medical humanities.
    Schlagwort(e): Language Arts & Disciplines ; Linguistics ; Language Arts & Disciplines ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::C Language and Linguistics::CB Language: reference and general
    Sprache: Englisch
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  • 20
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-06-21
    Beschreibung: The high importance of free radical chemistry for a variety of biological events, including ageing and inflammation, has attracted considerable interest in understanding the related mechanistic steps at the molecular level. Modelling the free radical chemical reactivity of biological systems is an important research area. When studying free-radical-based chemical mechanisms, biomimetic chemistry and the design of established biomimetic models come into play to perform experiments in a controlled environment, suitably designed to be a similar as possible to cellular conditions. This Special Issue provides readers with a wide overview of biomimetic radical chemistry, where molecular mechanisms have been defined and molecular libraries of products are developed to be used as traces for the discoveries of some relevant biological processes. Several subjects are presented, with five articles and five reviews written by specialists in the fields of DNA, proteins, lipids, biotechnological applications and bioinspired synthesis, with “free radicals” as the common denominator.
    Schlagwort(e): guanine ; guanyl radical ; tautomerism ; guanine radical cation ; oligonucleotides ; DNA ; G-quadruplex ; time-resolved spectroscopies ; reactive oxygen species (ROS) ; oxidation ; catalase mimics ; peroxide ; diiron-peroxo complexes ; structure/activity ; kinetic studies ; biomimetic chemistry ; cysteine ; ketone reduction ; free radicals ; pulse radiolysis ; kinetics ; DNA oxidation ; DNA hole transfer ; molecular dynamics ; quantum dynamics ; electron transfer ; charge transfer ; quantum coherence ; chemiluminescence ; reaction mechanisms ; singlet oxygen ; reactive oxygen species ; light emission ; crosslink ; dimerization ; protein oxidation ; radicals ; di-tyrosine ; di-tryptophan ; disulfides ; thiols ; aggregation ; proteomics ; mass spectrometry ; collagen ; riboflavin ; hyaluronic acid ; EPR spectroscopy ; keratoconus ; STEM ; DNA biosensor ; chemical nucleases ; DNA-drug interaction ; copper complexes ; metallodrugs ; MEP pathway ; antibiotics ; IspH ; LytB ; [4Fe-4S] cluster ; reductive dehydroxylation ; bioorganometallic intermediate ; inhibitors ; methionine ; neighboring group effect ; hydroxyl radical ; triplet state of carboxybenzophenone ; one-electron oxidants ; laser flash photolysis ; peptides ; proteins ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
    Sprache: Englisch
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  • 21
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-08-08
    Beschreibung: This Special Issue highlights fundamental changes to the questions that we can ask about both the recent past and deep time. Delve into the forefront of paleontological research with this Special Issue reprint. Renowned paleontologists from around the world share groundbreaking insights into ancient life on Earth. Discover the latest advances in fossil discovery, analytical techniques, interdisciplinary collaborations, and technological innovations that are shaping our understanding of evolution and the Earth's history. This collection of cutting-edge research is a must-read for scientists, researchers, and enthusiasts interested in the dynamic field of paleontology in the modern era.
    Schlagwort(e): REE ; Tyrannosaurus rex ; molecular paleontology ; geochemical taphonomy ; diagenesis ; bone ; protein ; collagen ; Hell Creek Formation ; cuticle ; Eocene ; Fur Formation ; insects ; melanin ; mo-clay ; pigment ; Stolleklint Clay ; structural coloration ; Ølst Formation ; fossil ; dinosaur ; paleoproteomics ; porphyrin ; keratin ; feather ; taphonomy ; degradation ; microbes ; CO2 ; apatite ; paleontology ; China ; history ; 20th century ; 21th century ; paleobiology ; history and philosophy of paleontology ; twenty-first-century paleontology ; paleobiological revolution ; technoscience and global issues ; fossil proteins ; rare earth elements ; soft-tissue preservation ; geochemistry ; soft tissues ; molecular preservation ; Hornerstown Formation ; shallow marine ; glauconite ; hybridization ; introgression ; ancient DNA (aDNA) ; hominin paleontology ; paleoanthropology ; Brachylophosaurus ; Judith River Formation ; ELISA ; RIA ; Venta Micena site ; VM-0 ; VM-1960 ; taxonomy ; morphometrics ; phylogeny ; evolution ; morphological clock ; molecular clock ; biodiversity ; palaeobiogeography ; macroevolution ; primates ; Cercopithecidae ; monkeys ; genotype:phenotype mapping ; dentition ; Equidae ; Equinae ; hipparionini ; protohippini ; equini ; paleoecology ; paleoclimatology ; biochronology ; steroids ; diet ; coprolites ; Gryphaea dilatata ; crystallographic texture ; pole figures ; neutron diffraction ; recrystallization ; thick-walled shells ; molecular taphonomy ; fossils ; preservation ; mass spectrometry ; dinosaurs ; Neanderthal ; Combe-Grenal ; juvenile ; mandible ; periodontitis ; tooth ; tartar ; SEM analysis ; n/a ; terrestrialization ; artrhopods ; Cambrian explosion ; molecular clocks ; palaeontology ; phylogenomics ; teeth ; enamel ; microanalysis ; Purussaurus ; Neoepiblema ; miocene ; ICP-MS ; MEV ; microscopy ; magnetic resonance imaging ; micro-computed tomography ; radiocarbon dating ; DNA barcoding ; synchrotron ; bone remodeling ; elemental analysis ; diagenetic alteration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
    Sprache: Englisch
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  • 22
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: In the year 2013, ‘selfie’ was named word of the year by Oxford Dictionaries in recognition of dramatic changes in frequency, prominence, and register of the term. This drastic increase in selfie-taking was spurred by two factors. The first was the advent of smartphones equipped with front cameras and preview screens that made it easy to compose a photographic self-portrait by a process of deliberately exploring one’s image, choosing a pose, and finally taking the picture. The second key change contributing to the rise of the selfie age was the increasing availability of internet connections. It is estimated that about 50% of the world population has access to the internet today (2018; https://www.internetworldstats.com). At the end of the past century, this percentage was a mere 1%. The growth of the internet infrastructure simultaneously spurred the development of social network applications such as Facebook, Twitter, Snapchat, and Instagram, providing accessible media for sharing photographs including photographic self-portraits. However, despite their tremendous reach and popularity, selfies have so far received relatively little attention by the scientific community, especially within psychology. Thus, we proposed a Frontiers in Psychology Research Topic to expand empirical and theoretical work on the massively popular, yet scientifically unexplored, phenomenon of the selfie. The articles published in this eBook offer a multifaceted insight into current scholarly work on this topic.
    Schlagwort(e): BF1-990 ; Q1-390 ; group selfies ; self-esteem ; Human Computer Interaction (HCI) ; self-presentation ; selfie ; viewing perspective ; perception bias ; smartphones ; social media ; internet ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 23
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-06-21
    Beschreibung: This Special Issue introduces recent research results on MEMS packaging and 3D integration whose subjects can be divided as follow; three papers on biocompatible implantable packaging, three papers on interconnect, three papers on bonding technologies, one paper on vacuum packaging, and three papers on modeling and simulation.
    Schlagwort(e): heterogeneous integration ; wafer bonding ; wafer sealing ; room-temperature bonding ; Au-Au bonding ; surface activated bonding ; Au film thickness ; surface roughness ; microelectromechanical systems (MEMS) packaging ; inkjet printing ; redistribution layers ; capacitive micromachined ultrasound transducers (CMUT) ; fan-out wafer-level packaging (FOWLP) ; adhesion ; thin film metal ; parylene ; neural probe ; scotch tape test ; FEM ; MEMS resonator ; temperature coefficient ; thermal stress ; millimeter-wave ; redundant TSV ; equivalent circuit model ; S-parameters extraction ; technology evaluation ; MEMS and IC integration ; MCDM ; fuzzy AHP ; fuzzy VIKOR ; fan-out wafer-level package ; finite element ; glass substrate ; reliability life ; packaging-on-packaging ; thermal sensors ; TMOS sensor ; finite difference time domain ; optical and electromagnetics simulations ; finite element analysis ; ultrasonic bonding ; metal direct bonding ; microsystem integration ; biocompatible packaging ; implantable ; reliability ; Finite element method (FEM) ; simulation ; multilayer reactive bonding ; integrated nanostructure-multilayer reactive system ; spontaneous self-ignition ; self-propagating exothermic reaction ; Pd/Al reactive multilayer system ; Ni/Al reactive multilayer system ; low-temperature MEMS packaging ; crack propagation ; microbump ; deflection angle ; stress intensity factor (SIF) ; polymer packaging ; neural interface ; chronic implantation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
    Sprache: Englisch
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  • 24
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-11-17
    Beschreibung: Symmetry can play an important role in the field of nonlinear systems and especially in the design of nonlinear circuits that produce chaos. Therefore, this Special Issue, titled “Symmetry in Chaotic Systems and Circuits”, presents the latest scientific advances in nonlinear chaotic systems and circuits that introduce various kinds of symmetries. Applications of chaotic systems and circuits with symmetries, or with a deliberate lack of symmetry, are also presented in this Special Issue. The volume contains 14 published papers from authors around the world. This reflects the high impact of this Special Issue.
    Schlagwort(e): chaos ; bifurcation ; closed curve equilibrium ; synchronization ; nonlinear equations ; iterative methods ; rotation–translation formula ; symmetric encryption ; chaotic map ; image encryption ; simultaneous confusion and diffusion ; chaotic oscillator ; lyapunov exponents ; poincare map ; integrated circuit ; fpga ; time-delay ; boolean networks ; hidden attractor ; amplitude control ; offset boosting ; cryptography ; substitution box ; postprocessing ; symmetry ; asymmetry ; chaotic system ; random bit generation ; logistic map ; chaos-based cryptography ; entropy ; prediction ; fractional-order ; glucose-insulin system ; chaotic attractor ; active control ; chaos theory ; electrical circuit analysis ; jerk circuit ; Chua’s diode ; system of differential equations ; quantum mechanics ; molecular quantum transitions ; singularity ; dozy chaos ; dozy-chaos mechanics ; charge transfer ; condensed matter ; direct and reverse processes ; optical band shapes ; Egorov resonance ; hyperchaotic behavior ; arduino microcontrollers ; optical channel ; chaotic flow ; hyperbolic sinusoidal function ; voice encryption ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
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  • 25
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-08-08
    Beschreibung: The World Health Organization recommends the consumption of plant foods instead of animal-origin foods due to their high levels of saturated fat and cholesterol. Consumption of plant products has led to research on the beneficial properties of their components beyond basic nutrients. Vegetable-derived peptides have shown multifunctional effects related to chronic diseases, attracting interest from the food, nutraceutical, and pharmaceutical industries. This reprint highlights studies on various vegetable extracts, such as chestnut, quinoa, amaranth, buckwheat, and Protium heptaphyllum gum resin, which have demonstrated antimicrobial, anti-inflammatory, and cholesterol-regulating properties. Specific compounds derived from plants, such as methyl p-coumarate and lupin protein hydrolysate, have shown effectiveness in reducing inflammation and anxiety, respectively. A vegetable extract of rosemary has been studied for its potential to treat osteogenesis imperfecta. Moreover, this repprint reviews Lycium barbarum berries, essential oils from Annonaceae species, antioxidant compounds, phytosterols, and natural compounds for the prevention and treatment of oral mucositis was discussed. Overall, these studies suggest that vegetable-derived bioactive compounds could serve as new nutraceuticals to prevent and treat a wide range of chronic diseases.
    Schlagwort(e): hypercholesterolemia ; gene expression ; HMGCR ; PCSK9 ; PPARα ; enzymatic activity ; molecular docking ; statin ; monacolin ; breu branco ; seed storage proteins ; peptides ; anti-inflammatory ; antioxidant ; trypsin inhibitors ; quinoa ; amaranth ; buckwheat ; in vitro gastro-intestinal digestion ; natural products ; Brazilian species ; essential oil ; applications ; phytosterols ; neurodegeneration ; Alzheimer’s disease ; blood brain barrier ; obesity ; oxidative stress ; dyslipidemia ; diabetes ; enzyme-assisted extraction ; plant material ; phenolic compounds ; oligosaccharides ; prebiotic ; nanocellulose ; nanofibers ; fermentation ; sustainability ; cancer ; drug delivery ; oral mucositis ; treatment ; lupin ; protein hydrolysates ; anxiety ; ApoE−/− ; functional foods ; peptidomics ; rosemary extract ; collagen type I ; unfolded protein response ; autophagy ; proteasome ; skin fibroblasts ; apoptosis ; osteogenesis imperfecta ; asthma ; methyl p-coumarate ; Th2 cytokines ; eosinophil ; NF-κB ; Castanea sativa shells ; Subcritical Water Extraction (SWE) ; antimicrobial activity ; goji berries ; pro-healthy effects ; phenolics ; biological properties ; functional ingredients ; in vitro cultures ; Ruta montana ; coumarins ; alkaloids ; antibiofilm formation ; antibacterial activity ; antioxidant activity ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
    Sprache: Englisch
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  • 26
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Schlagwort(e): QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 27
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    Frontiers Media SA
    Publikationsdatum: 2024-03-31
    Beschreibung: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.
    Schlagwort(e): QP1-981 ; Q1-390 ; Vitamin D ; Immune System ; Genomics ; vitamin D receptor ; Physiology ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Sprache: Englisch
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  • 28
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    UJ Press
    Publikationsdatum: 2024-03-24
    Beschreibung: Linguistics for Legal Interpretation is a language resource for scholars and practitioners of law who engage and work with statutory interpretation. It draws on lexical semantics, pragmatics and sociolinguistics to both understand and solve language challenges central to the interpretation effort. In addition, this book offers best practice guidelines for dictionary use as well as an introduction to corpus linguistic methods to assist legal interpreters in determining either ordinary or technical meaning. The book illustrates the various language tools and devices by applying them to case law and legislation, and it does so in an accessible style of writing. Terrence R Carney is Associate Professor of Afrikaans Linguistics at the University of South Africa. He specialises in the language of law.
    Schlagwort(e): legal language, linguistics, legal interpretation ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 29
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-04-05
    Beschreibung: Considering the worldwide problem of aquatic pollution, we proposed this reprint, which presents a collection of articles on different aspects of environmental pollution, from monitoring to the evaluation of toxicity. In particular, the volume concerns the issues specifically related to emerging contaminants in aquatic environments, such as plastics and pharmaceuticals. However, to confer to this volume a more holistic view, some articles on priority pollutants, such as heavy metals and pesticides, are also reported.
    Schlagwort(e): aquatic ecosystems ; pollution ; monitoring ; toxic effects ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
    Sprache: Englisch
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  • 30
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-04-05
    Beschreibung: This Special Issue of the journal Axioms collects submissions in which the authors report their perceptions and results in the field of mathematical physics and/or physical mathematics without any preconditions of the specific research topic. The papers are intended to provide the reader with a broad window into the status of the research field showing our understanding of how a known concept changes our thinking in that area of science. The papers in the Special Issue highlight the current two issues in physics and mathematics under hot debate: fractional calculus and entropy.
    Schlagwort(e): weak detonation ; high activation regime ; nonlinear PDEs ; Fuchsian reduction analysis ; Lorentz transformation ; blow-up ; hot spot ; chemically reactive flows ; nonlinear equations in partial derivatives ; hyperbolic equations ; Bäcklund transformations ; Clairin’s method ; differential relationships ; the Liouville equation ; symbolic calculus ; canonical system of q-difference equations ; q-Euler integral ; multi-term fractional differential equation ; quasilinear equation ; Riemann–Liouville fractional derivative ; defect of Cauchy type problem ; fixed point theorem ; initial-boundary value problem ; deformed numbers ; deformed algebras ; deformed calculus ; nonadditive entropy ; vibration control ; boundary control ; intermediate state control ; separation of variables ; Riemann–Liouville fractional differential equations ; nonlocal boundary conditions ; positive parameters ; positive solutions ; existence ; nonexistence ; Patlak–Keller–Segel systems ; the Cattaneo model of chemosensitive movement ; hyperbolic models ; shock waves ; conservation laws ; constrained Hamiltonian system ; canonicalization ; symplectic method ; numerical simulation ; extended Chebyshev functional ; generalized proportional Hadamard fractional integral operator ; manipulation system ; geometric approach ; noninteraction ; two-phase flow ; Sobolev spaces ; analytic semigroups ; fractional interpolation ; local and global solutions ; seismic tensorial force ; far-field seismic waves ; near-field seismic waves ; seismic mainshock ; quasi-static deformations ; mathematical physics ; Elliott Lieb ; the International Association of Mathematical Physics (IAMP, history and development) ; Letters in Mathematical Physics (LMP) ; history ; God as an (optional) axiom ; metamathematics ; symmetries ; particle physics ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBT Probability & statistics
    Sprache: Englisch
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  • 31
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: Postkoloniale Konstellationen lassen sich nicht (mehr) in das Eigene und das Andere, in das Originäre und das Nachgeahmte, in ein Hier und Dort auseinanderdividierenden. Sie sind geprägt von Verflechtungen, Hybri-disierungen und wechselseitigen Aneignungsprozessen. In diesem Band analysiert die Autorin Texte von Jurij Brězan, Irena Brežná, Mascha Dabić, Róža Domašcyna, Olga Grjasnowa, Barbi Marković, Olga Martynova und Aleksandar Tišma. Sie zeigt auf, dass alle Werke sich mit multiplen Zuge-hörigkeiten, Mehrsprachigkeit und Übersetzung auseinandersetzen. Die Texte dekonstruieren Grenzen sprachlicher und kultureller Zugehörigkeit, thematisieren aber auch Diskriminierung, Rassismus und Antisemitismus. Damit beschreiben sie mehrsprachige Welten jenseits von hegemonialer Einsprachigkeit.
    Schlagwort(e): Aleksandar Tišma ; Barbi Marković ; deutsche ; Einsprachigkeit ; Hitzke ; Jurij Brězan ; Mehrsprachigkeit ; Olga Grjasnowa ; Olga Martynova ; Postkoloniale Literatur ; Slavisch ; Sorbische Literatur ; Texte ; transkulturell ; Übersetzung ; Verflechtung ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general
    Sprache: Deutsch
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  • 32
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-07-06
    Beschreibung: The first experiments on electron scattering were completed before the “official” discovery of this particle by J. J. Thomson. In spite of this, our knowledge of cross sections is still far from complete.More recent experiments had some unexpected results, like selective fragmentation of DNA constituents by low-energy electrons, or “reverse” phenomena, i.e., synthesis of simple amino acids from inorganic precursors, triggered by slow electrons. The most recent need for cross sections comes from modeling plasmas for industrial and thermonuclear applications, and atmospheres of solar and extra-solar planets.Both fundamental research (experiments, theory, reviews) and applications of electron-scattering cross sections in various processes are welcome.
    Schlagwort(e): ionization ; electron ; positron ; few body ; electron scattering ; integral cross sections ; alcohols ; isomeric effect ; butanol ; pentanol ; electron mobility ; multiple-scattering effects ; disordered systems ; weak localization ; electron and positron scattering ; spin asymmetry ; critical minima ; total polarization ; coulomb glory ; water ; vibrational excitation ; R-matrix ; electron-molecule collisions ; interstellar medium ; model potential ; wave-packet propagation ; vibrational cross-section ; backscattering ; electron optics ; inelastic collisions ; numerical simulations ; electron ionization ; electron capture ; helium droplets ; cross section ; MCDF wavefunctions ; wavelengths ; transition rates ; relativistic distorted wave method ; cross sections ; rate coefficients ; ionizing radiation ; dissociative electron attachment ; mass spectrometry ; DNA damage ; cross-section calculations ; plasma simulation ; electron atomic collisions ; ionization cross section ; approximation of cross sections ; alkali metals ; noble gases ; electron elastic scattering ; scattering cross-sections ; positron scattering ; total cross-sections ; dispersion relation ; electron scattering cross sections ; electron transport in gases ; electron track simulation ; positron impact ionization ; positron-molecule scattering ; binary-encounter-Bethe ; argon optical emission spectroscopy ; plasma processing ; coronal models ; collisional-radiative model ; nonlocal thermodynamic equilibrium plasmas ; population kinetics ; radiation transport ; opacity effects ; Non-Maxwellian plasmas ; metastable states ; electron-impact ionization ; BEB approach ; elementary processes in plasmas ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
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  • 33
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Glial cells are no longer considered passive bystanders in neuronal brain circuits. Not only are they required for housekeeping and brain metabolism, they are active participants in regulating the physiological function and plasticity of brain circuits and the online control of behavior both in invertebrate and vertebrate model systems. In invertebrates, glial cells are essential for normal function of sensory organs (C. elegans) and necessary for the circadian regulation of locomotor activity (D. melanogaster). In the mamallian brain, astrocytes are implicated in the regulation of cortical brain rhythms and sleep homeostasis. Disruption of AMPA receptor function in a subset of glial cell types in mice shows behavioral deficits. Furthermore, genetic disruption of glial cell function can directly control behavioral output. Regulation of ionic gradients by glia can underlie bistability of neurons and can modulate the fidelity of synaptic transmission. Grafting of human glial progenitor cells in mouse forebrain results in human glial chimeric mice with enhanced plasticity and improved behavioral performance, suggesting that astrocytes have evolved to cope with information processing in more complex brains. Taken together, current evidence is strongly suggestive that glial cells are essential contributors to information processing in the brain. This Research Topic compiles recent research that shows how the molecular mechanisms underlying glial cell function can be dissected, reviews their impact on plasticity and behavior across species and presents novel approaches to further probe their function.
    Schlagwort(e): RC321-571 ; Q1-390 ; Cerebellum ; C. elegans ; Astrocytes ; DREADD ; Cortex ; plasticity ; Gq ; Behavior ; glia ; Hippocampus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 34
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    Firenze University Press
    Publikationsdatum: 2024-03-24
    Beschreibung: The 7th International Conference of the Gruppo di Studi sulla Comunicazione Parlata, dedicated to the memory of Claire Blanche-Benveniste, chose as its main theme Speech and Corpora. The wide international origin of the 235 authors from 21 countries and 95 institutions led to papers on many different languages. The 89 papers of this volume reflect the themes of the conference: spoken corpora compilation and annotation, with the technological connected fields; the relation between prosody and pragmatics; speech pathologies; and different papers on phonetics, speech and linguistic analysis, pragmatics and sociolinguistics. Many papers are also dedicated to speech and second language studies. The online publication with FUP allows direct access to sound and video linked to papers (when downloaded).
    Schlagwort(e): thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFF Historical and comparative linguistics ; thema EDItEUR::D Biography, Literature and Literary studies
    Sprache: Englisch
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  • 35
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-07-06
    Beschreibung: It is our pleasure to present this Special Issue of Molecules entitled “Food Processing and Its Impact on Phenolic and other Bioactive Constituents in Food”. Bioactive compounds including phenolic ingredients have long been used as important constituents of a healthy diet. As a result, consumer awareness about the important role of high-quality products rich in bioactive compounds—especially phenolic compounds—in human nutrition, health, and prevention against diseases has increased. Additionally, methods for food processing, regardless of the technology used, have a huge impact on the quality of the final products. Therefore, the big challenges for scientists lie in the monitoring of changes during food processing and the optimization of technology to achieve the minimal degradation of nutrients (including phenolic compounds). Thus, for this Special Issue, I encourage you to read some interesting papers aimed at bringing the latest scientific news, insights, and advances in the field of food processing and its impact on bioactive constituents in food, especially phenolic compounds. The information presented will certainly arouse considerable interest among a large group of our readers from different disciplines and research fields.
    Schlagwort(e): apple ; phenolic compounds ; genetic resources ; HPLC-DAD ; thyme ; oregano ; dry herbs ; polyphenols ; chlorophyll ; carotenoids ; microbial ; cytotoxicity ; dissolution test ; functional food ; innovative food ; drying ; natural food ; Helianthus tuberosus ; pro-healthy properties ; plant polyphenols ; food processing ; phenolic content ; bioavailability ; bioaccessibility ; coffee Arabica ; roasting process ; brewing methods ; antioxidant activity ; flavonoids ; caffeine ; pH of infusions ; tannins ; snack ; baking ; carotenoids content ; chlorophyll content ; total polyphenols content ; calorific value ; sensory properties ; sourdough fermentation ; inoculation ; lactic acid bacteria ; FODMAP ; fructans ; antioxidants ; chocolate ; free radical scavenging activity ; reducing power ; functionalization of food ; electronic nose analysis ; isoflavone conversion ; thermal process ; immature seeds ; mature seeds ; internal water content ; konjac ; linseed flour ; fat substitute ; volatile compounds ; lipid oxidation ; encapsulation ; Mauritia flexuosa (aguaje) ; controlled dehydration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
    Sprache: Englisch
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  • 36
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-04-05
    Beschreibung: The eradication of vector-borne diseases is threatened by the limited range of available insecticides, leading, inevitably, to the development of resistance. This is particularly concerning for malaria control, which relies heavily on insecticide-treated nets (ITNs) and indoor residual sprays (IRS). New chemistries are being developed, and innovative deployment of insecticides may play a role in overcoming resistance, either through new types of tools or new means of distribution. A variety of novel product types and vector control strategies are under development and evaluation, which is to be celebrated, but a strong evidence base is needed to guide effective operational deployment decisions. Novel approaches should be supported by robust data collected using appropriate and validated methods to monitor efficacy, durability, and any emerging resistance. This reprint presents original research into developing and characterizing new vector control products, as well as understanding and monitoring insecticide resistance. Review articles explore the impact of insecticide resistance and offer guidance on insecticide choice in the face of pyrethroid resistance. Consensus methodologies are presented, in the form of standard operating procedures (SOPs) designed to be adopted and used to generate reproducible data that can be compared and interpreted across and between studies. It is hoped that this collection of articles offers inspiration and guidance on how consistent data can be generated to inform more effective development, evaluation, and use of new and existing vector control tools.
    Schlagwort(e): prallethrin ; insecticide ; spatial treatment ; mosquito fitness ; protection ; pyrethroids ; Aedes albopictus ; Culex pipiens ; life tables ; mosquito ; bite-proof garment ; model ; textile ; non-insecticidal ; physical barrier ; insecticide selection ; out-crossing ; strain authentication ; laboratory screening ; pyrethroid ; pyrethroid resistance ; insecticide resistance ; insecticide resistance management ; vector control ; malaria ; malaria control ; Anopheles ; host-seeking behavior ; insecticide exposure ; pathogen transmission ; Aedes aegypti ; Anopheles gambiae ; ATSB ; Culex quinquefasciatus ; Iroquois ; RNAi ; Saccharomyces cerevisiae ; yeast ; Anopheles mosquito ; fertility ; ovary development ; pyriproxyfen (PPF) ; side-effects ; machine learning ; image classification ; automated identification ; convolutional neural network ; insecticide-treated net (ITN) ; PBO ITN ; synergist ITN ; dual-AI ITN ; insecticide resistance management (IRM) ; method validation ; durability monitoring ; bioinsecticide ; disease transmission ; insecticide-resistance ; mosquito-borne disease ; mosquito control ; natural compounds ; phytochemical ; malaria vector ; insecticide treated nets ; cytochrome P450s ; kdr ; cuticular resistance ; deltamethrin ; imidacloprid ; bifenthrin ; β-cyfluthrin ; etofenprox ; α-cypermethrin ; λ-cyhalothrin ; thiacloprid ; mosquitoes ; Attractive Toxic Sugar Bait (ATSB) ; Attractive Targeted Sugar Bait (ATSB) ; diagnostic bioassay ; resistance monitoring ; insecticide-treated nets (ITN) ; strain characterisation ; method development ; product evaluation ; quality control (QC) ; dual active ingredients (dual-AI) ; bioefficacy ; IRS ; application technology ; broflanilide ; clothianidin ; pirimiphos-methyl ; WHO tube ; WHO tunnel test ; ITNs ; interceptor ; interceptor G2 ; membrane ; human arm ; rabbit ; bioassay ; bio-efficacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
    Sprache: Englisch
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  • 37
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.
    Schlagwort(e): QD1-999 ; Q1-390 ; glucose-6-phosphate dehydrogenase ; hydroxyurea/hydroxycarbamide ; n/a ; cord blood ; screening ; hemoglobin pattern ; capillary electrophoresis ; sickle cell disease ; (recommended) screening panel ; vaso-occlusive crisis ; Guthrie spots ; newborn screening) ; foetal haemoglobin ; harmonisation ; review ; birth prevalence ; G6PD deficiency ; prevention ; end-organ damage ; thalassemia ; MALDI-TOF ; IEF ; acute chest syndrome ; India ; sickle cell and thalassaemia screening programme ; ‘Getting to Outcomes’ ; newborn screening ; hemoglobinopathy ; service users ; public health engagement ; automated HPLC ; Kaduna State ; gene therapy for haemoglobinopathies ; ?-globin gene ; methods ; neonatal screening program ; malaria ; Plasmodium vivax ; sub-Saharan Africa ; patient organisations ; health policy ; pathophysiology ; Sickle Cell Disease ; mass spectrometry ; sickle cell disorder ; neonatal screening ; non-tribal ; Nigeria ; point-of-care ; HPLC ; laboratory methods ; registry ; patient advocacy ; bone marrow transplant ; anaemia ; hemoglobinopathies ; tribal ; newborn ; burden of disease ; patient representatives ; diagnostics ; policy making ; haemolysis ; Caribbean ; high performance liquid chromatography (HPLC) ; sickle cell disease (SCD) ; implementation science ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Sprache: Englisch
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  • 38
    Publikationsdatum: 2024-03-23
    Beschreibung: Acta Slavica Estonica is an international series of publications on current issues of Russian and other Slavic languages, literatures and cultures. This volume continues the tradition of publishing studies on the history and culture of the Old Believers in Estonia. It includes research papers on the topic, as well as transcripts of recorded texts from the Old Believers. The special focus of the volume is on the island Piirissaar, its history, architecture, people and their language, customs and traditions.
    Schlagwort(e): cultural studies ; Slavic studies ; Russian linguistics ; Russian dialects ; Russian onomastics ; folklore ; Russian lexicology ; old believers ; idiolects ; thema EDItEUR::1 Place qualifiers::1D Europe::1DT Eastern Europe::1DTE Estonia ; thema EDItEUR::2 Language qualifiers::2A Indo-European languages::2AG Slavic (Slavonic) languages::2AGR Russian ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs::QRM Christianity::QRMB Christian Churches, denominations, groups::QRMB2 Orthodox and Oriental Orthodox Churches ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBG Popular beliefs and controversial knowledge::JBGB Folklore studies / Study of myth (mythology) ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSC Rural communities ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSL Ethnic studies::JBSL1 Ethnic groups and multicultural studies
    Sprache: Russisch , Estnisch
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  • 39
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: The work consists of two parts. The first part deals exclusively with the aspect properties of Russian prefigured verbs. A perfective analysis for Russian is proposed, which allows to grasp the semantic differences between imperfective Simplizia and its derivative derivatives in semantic terms. The second part of the thesis is an application of the proposed perfective analysis to Russian pere-prefixed verbs. It is shown that the meaning variants of pere-prefixed verbs in Russian can be derived from a general prefix scheme and the semantics of the stem verb.
    Beschreibung: Die Arbeit besteht aus zwei Teilen. Der erste Teil befaßt sich ausschließlich mit den aspektuellen Eigenschaften russischer präfigierter Verben. Es wird eine Perfektivanalyse für das Russische vorgeschlagen, die es ermöglicht, die semantischen Unterschiede zwischen imperfektiven Simplizia und ihren perfektiven Derivata in semantischen Termen zu erfassen. Der zweite Teil der Arbeit stellt eine Anwendung der vorgeschlagenen Perfektivanalyse auf russische pere-präfigierte Verben dar. Es wird gezeigt, daß die Bedeutungsvarianten pere-präfigierter Verben im Russischen aus einem allgemeinen Präfixschema und der Semantik des Stammverbs abgeleitet werden können.
    Schlagwort(e): Analyse ; Demjjanow ; Eine ; Fallstudie ; imperfektives Simplizia ; pere ; Perfektivaxiome ; Perfektivierung im Lexikon ; Perfektivierungspräfigierung ; Perfektiv-Imperfektivtest ; Russischen ; semantische ; Verbpräfigierung ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 40
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-01-05
    Beschreibung: Phenolic compounds in food such as fruits, vegetables, wine, spices, and oils have been characterized and their possible effects on human health has been studied in depth. Several technological aspects have also been considered concerning the sustainable extraction of phenolic compounds, the long-term storage effects, and the influence of fermentation and boiling techniques on their properties.
    Schlagwort(e): chestnut ; water curing ; non-targeted MS analysis ; antioxidants ; Arecaceae ; polyphenols ; volatile content ; antioxidant activity ; liquid chromatography ; inflammation ; lung ; oxidative damage ; antiviral ; polyphenol ; phenolic acids ; flavonoids ; Vicia faba ; functional food ; green solvents ; biologically active compounds ; selective separation ; medicinal plants ; ultrasonic-assisted extraction ; microwave-assisted extraction ; kombucha ; black tea ; long-term storage ; antioxidant scavenging activity ; total phenolic content ; meat quality ; antimicrobial activity ; C. scolymus ; food quality ; beverages ; health properties ; antioxidant activities ; fibrinogen ; albumin ; rutin ; tannic acid ; resveratrol ; binding properties ; first order ; kinetic modelling ; zero order ; food processing ; herbal tea ; boiling ; EVOO ; vegetables ; phenolic compounds ; thermal treatment ; processing techniques ; bioaccessibility ; bioavailability ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
    Sprache: Englisch
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  • 41
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-07-06
    Beschreibung: The articles in this Special Issue cover a very wide range of topics related to the cultivation, management and use of fast-growing tree species. In addition to research on breeding and on the influence of pruning practices on the height growth of paulownia, three articles deal with the influence of site characteristics and nutrient availability on the physiology and yield security of fast-growing tree species. Another article focuses on the modeling of soil carbon in Salix plantations, while the article by Boruszewski et al. reports on potentially suitable areas for the planting of fast-growing tree species in Poland. Zitzmann and Rode examine the impact of short-rotation plantation management on phytodiversity, while Helbig et al. deal with the influence of leaf feeding on the growth of poplars and willows. Finally, Hernandez-Estrada et al. describe the dry matter loss of poplar wood chips during storage.
    Schlagwort(e): woody biomass crops ; bioenergy ; biodiversity ; species richness ; flora ; vascular plants ; short rotation coppices ; poplars ; willows ; feeding simulation ; defoliation ; herbivory ; short rotation coppice ; phosphatase activity ; nutrient content ; growth stages ; biomass ; willow ; Salix ; capacity ; European larch ; fast-growing trees ; plantations ; plantation area ; poplar cultivar “Hybrid 275” ; sown area ; biomass production ; life cycle assessment ; climate impact ; soil organic carbon ; genotypic difference ; CRISPR/Cas9 ; genome editing ; Populus ; INRA 717-1B4 ; pyramidal plant habitus ; leaf petiole angle ; branch angle ; nitrogen ; phosphorus ; carbon ; physiology ; F. mandshurica ; Robinia pseudoacacia L. ; photosynthetic vitality ; chlorophyll and phenol content ; nutrition supply ; dry matter yield ; land reclamation ; spring pruning ; year-long pruning ; branching ; angle diversion of sprout ; dry matter losses ; poplar wood chips ; laboratory scale ; cultivable saproxylic microbiota ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
    Sprache: Englisch
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  • 42
    Publikationsdatum: 2024-04-05
    Beschreibung: In this EBook, we highlight how newly emerging techniques for non-invasive manipulation of the human brain, combined with simultaneous recordings of neural activity, contribute to the understanding of brain functions and neural dynamics in humans. A growing body of evidence indicates that the neural dynamics (e.g., oscillations, synchrony) are important in mediating information processing and networking for various functions in the human brain. Most of previous studies on human brain dynamics, however, show correlative relationships between brain functions and patterns of neural dynamics measured by imaging methods such as electroencephalography (EEG), magnetoencephalography (MEG), near-infrared spectroscopy (NIRS), positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). In contrast, manipulative approaches by non-invasive brain stimulation (NIBS) have been developed and extensively used. These approaches include transcranial magnetic stimulation (TMS) and transcranial electric stimulation (tES) such as transcranial direct current stimulation (tDCS), alternating current stimulation (tACS), and random noise stimulation (tRNS), which can directly manipulate neural dynamics in the intact human brain. Although the neural-correlate approach is a strong tool, we think that manipulative approaches have far greater potential to show causal roles of neural dynamics in human brain functions. There have been technical challenges with using manipulative methods together with imaging methods. However, thanks to recent technical developments, it has become possible to use combined methods such as TMS–EEG coregistration. We can now directly measure and manipulate neural dynamics and analyze functional consequences to show causal roles of neural dynamics in various brain functions. Moreover, these combined methods can probe brain excitability, plasticity and cortical networking associated with information processing in the intact human brain. The contributors to this EBook have succeeded in showcasing cutting-edge studies and demonstrate the huge impact of their approaches on many areas in human neuroscience and clinical applications.
    Schlagwort(e): RC321-571 ; Q1-390 ; non-invasive brain stimulation NIBS ; TMS-EEG ; Transcranial magnetic stimulation TMS ; transcranial electric stimulation tES ; Coregistration ; Near-infrared spectroscopy NIRS ; Functional magnetic resonance imaging fMRI ; transcranial direct current stimulation tDCS ; transcranial alternating current stimulation tACS ; transcranial random noise stimulation tRNS ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 43
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-02-01
    Beschreibung: This book presents the advances in plant salinity stress and tolerance, including mechanistic insights revealed using powerful molecular tools and multi-omics and gene functions studied by genetic engineering and advanced biotechnological methods. Additionally, the use of plant growth-promoting rhizobacteria in the improvement of plant salinity tolerance and the underlying mechanisms and progress in breeding for salinity-tolerant rice are comprehensively discussed. Clearly, the published data have contributed to the significant progress in expanding our knowledge in the field of plant salinity stress and the results are valuable in developing salinity-stress-tolerant crops; in benefiting their quality and productivity; and eventually, in supporting the sustainability of the world food supply.
    Schlagwort(e): watermelon ; salt stress ; RNA-seq ; amino acids ; endocytosis ; Arabidopsis thaliana ; halophyte ; high-affinity potassium transporter (HKT) ; Na+ transporter ; salt tolerance ; Sporobolus virginicus ; aquaporins ; barley ; ion transport ; oocytes ; plasma membrane intrinsic proteins (PIPs) ; GmbZIP15 ; transcription factor ; drought stress ; soybean ; biotechnology breeding ; high-throughput sequencing ; QTLs ; rice ; halophytic wild barley ; salinity ; osmotic stress ; metabolome ; transcriptome ; ionome ; stress adaptation ; Hordeum marinum ; aquaporin ; Zygophyllum xanthoxylum ; plant growth ; abiotic stress ; sensing ; signaling ; transcription factors ; osmoregulation ; antioxidation ; ion homeostasis ; jasmonates ; jasmonate signaling pathway ; crosstalk ; exogenous jasmonate applications ; GWAS ; PGPR ; ACC deaminase ; seed priming ; IAA ; cell wall integrity ; cell wall sensor ; LRXs ; CrRLK1Ls ; Millettia pinnata ; calmodulin-like ; heterologous expression ; halophiles ; plant growth-promoting rhizobacteria (PGPR) ; RNA sequence analysis (RNA-seq) ; quantitative reverse transcriptase PCR (qRT-PCR) ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
    Sprache: Englisch
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  • 44
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-05-06
    Beschreibung: In recent years, new and emerging digital technologies applied to food science have been gaining attention and increased interest from researchers and the food/beverage industries. In particular, those digital technologies that can be used throughout the food value chain are accurate, easy to implement, affordable, and user-friendly. Hence, this Special Issue (SI) is dedicated to novel technology based on sensor technology and machine/deep learning modeling strategies to implement artificial intelligence (AI) into food and beverage production and for consumer assessment. This SI published quality papers from researchers in Australia, New Zealand, the United States, Spain, and Mexico, including food and beverage products, such as grapes and wine, chocolate, honey, whiskey, avocado pulp, and a variety of other food products.
    Schlagwort(e): sensory ; physicochemical measurements ; artificial neural networks ; near infra-red spectroscopy ; wine quality ; machine learning modeling ; weather ; consumer acceptance prediction ; data fusion ; emotion recognition ; facial expression recognition ; galvanic skin response ; machine learning ; neural networks ; sensory analysis ; avocado ; cultivars ; preference mapping ; sensory evaluation ; sensory descriptive analysis ; consumer science ; unifloral honeys ; botanical origin ; physicochemical parameters ; classification ; natural language processing ; deep learning ; sensory science ; flavor lexicon ; long short-term memory ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
    Sprache: Englisch
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  • 45
    Publikationsdatum: 2024-04-05
    Beschreibung: Bálint’s syndrome is named after the Hungarian physician who first reported a remarkable case of a man with complex visuospatial deficits following bilateral lesions within parietal and occipital cortex (Bálint, 1909). The syndrome has three primary symptoms: simultanagnosia (impaired spatial awareness of more than one object at time), optic ataxia (misreaching to visual targets) and ocular apraxia (described by Bálint as “psychic paralysis of gaze”). Balint’s patients not only cannot perceive more than one object at time and therefore show poor comprehension of multi-object visual scenes i.e. poor detection of all the objects present and difficulty in grasping the relationship between them; in addition they typically fail to reach towards location of the single object, which they can perceive. The deficit of the allocation of spatial attention in Balint’s syndrome has been linked to a problem in feature binding which results in illusory conjunctions. Patients with Balint’s syndrome also show deficits in global processing i.e. when integration of multiple local elements into global compound shapes is required. Consequently, Balint’s syndrome provides a unique opportunity to study the nature and neuroanatomy of human visuospatial processing, in particular multi-level object representation, spatial awareness and the distribution of visual attention. The studies collected here cover both the anatomical and the cognitive mechanisms of the different symptoms associated with the syndrome. Furthermore, the dissociations between the components of Bálints’ syndrome, in particular simultanagnosia and optic ataxia, can also co-occur with visual neglect and extinction and the different combinations of reported lesions raises a question about the status of the syndrome and whether it should be merely treated as a historical compilation of symptoms which may or may not coexist cohesively. This interesting argument is raised here.
    Schlagwort(e): RC321-571 ; Q1-390 ; posterior cortical atrophy ; Balints syndrome ; optic ataxia ; Posterior parietal cortex ; simultanagnosia ; ocular apraxia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 46
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    Firenze University Press
    Publikationsdatum: 2024-03-24
    Beschreibung: The volume collects the proceedings of the conference “Firenze e la lingua italiana tra nazione ed Europa” (Florence and the Italian language between nation and Europe), which was held from on May 27 and 28 2004 in the Aula Magna of the University of Florence and the Accademia della Crusca. As known, Florence played a central role in the process of national linguistic unification and thanks to its international vocation the city has promoted the spread and knowledge of the Italian language and culture all over Europe and in the world. Beyond any celebratory enthusiasm, the conference has been an occasion of open discussion on the cultural identity of the city in the contemporary context, through a critical reflection on its history (in particular on some significant moments of the Florentine culture between the nineteenth and twentieth centuries) and on its linguistic primacy.
    Schlagwort(e): Lingua italiana ; Linguistica ; Storia ; Atti di convegno ; Firenze ; Europa ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Italienisch
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  • 47
    Publikationsdatum: 2024-03-24
    Beschreibung: In der Reihe Slavistische Beiträge werden vor allem slavistische Dissertationen des deutschsprachigen Raums sowie vereinzelt auch amerikanische, englische und russische publiziert. Darüber hinaus stellt die Reihe ein Forum für Sammelbände und Monographien etablierter Wissenschafter/innen dar.
    Schlagwort(e): Ende ; Entstehung ; Entwicklung ; Linguistik ; Mareš ; Periode ; Philologie ; phonologischen ; Russland ; seine ; Slavische Sprachwissenschaft ; slavischen ; Spracheinheit ; Systems ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 48
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    Language Science Press | Language Science Press
    Publikationsdatum: 2024-03-24
    Beschreibung: This book brings together papers that discuss social and structural aspects of language contact and language change. Several papers look at the relevance of historical documents to determine the linguistic nature of early contact varieties, while others investigate the specific processes of contact-induced change that were involved in the emergence and development of these languages. A third set of papers look at how new datasets and greater sensitivity to social issues can help to (re)assess persistent theoretical and empirical questions as well as help to open up new avenues of research. In particular they highlight the heterogeneity of contemporary language practices and attitudes often obscured in sociolinguistic research. The contributions all focus on language variation and change but investigate it from a variety of disciplinary and empirical perspectives and cover a range of linguistic contexts.
    Schlagwort(e): Language Arts & Disciplines ; Linguistics ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
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  • 49
    Publikationsdatum: 2024-04-05
    Beschreibung: The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways and functions of membrane guanylate cyclases in different tissues of the body and their interplay with intracellular sensory signals where in many cases, cyclic GMP along with Ca2+ have taken on roles as synarchic co-messengers.
    Schlagwort(e): RC321-571 ; Q1-390 ; Glaucoma ; Visceral Pain ; Calcium ; membrane guanylate cyclase ; ANF-RGC ; Gene Therapy ; Cyclic GMP ; synaptic plasticity ; trafficking ; ROS-GC ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 50
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    Taylor & Francis | New Perspectives on Goffman in Language and Interaction | Routledge
    Publikationsdatum: 2024-03-24
    Beschreibung: “Attention” is a primordial topic throughout Goffman’s work. Already his dissertation thesis (1953) includes a separate chapter on “the organization of attention”. In his later studies he developed various concepts related to attention, such as focused/unfocused interaction or “civil inattention”. Although attention is evidently a crucial dimension of the interactional order, Goffman did not elaborate this topic systematically. The study of attention was later refined and enriched by conversation analysts who underlined the role of visual displays of attentiveness in social interaction. Against the backdrop of the notion of “focused interaction”, this paper examines how the psychological approach to “joint attention” differs from or amplifies Goffman’s studies. Based on some of Cartier-Bresson’s photos, it is shown that the contrasting set of focused/unfocused interaction needs to be supplemented by a third type of attention order, in which members are collectively oriented to an outward event. After a discussion of some of the practices of sustaining and re-establishing a focus of attention, empirical evidence is provided that certain interactional purposes can be achieved by displaying inattention. In the final discussion of Goffman’s concept of “civil inattention”, some historical and sociological dimensions are pointed out along which this concept can be further studied.
    Schlagwort(e): co-presence; co-present bodies within space; social interaction; interactional sociolinguistics; interactional foundations of the self; participation; Erving Goffman; Lorenza Mondada; conversation analysis; sociolinguistics; interactional linguistics; language sciences; ethnomethodology; Anssi Peräkylä; self and identity; interaction studies; language and interaction; language and social interaction ; thema EDItEUR::C Language and Linguistics::CB Language: reference and general ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
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  • 51
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-02-02
    Beschreibung: This reprint reviews a crop pest management use for several essential oils and the properties of an excellent lemon (citral) source. Research is reported on the biological properties of enhanced lemon oil along with the human intake of citrus beverages and the less common medicinal mastiha oil. Oils and hydrolates of rosemary and lavender were analyzed by headspace/GC-MS to better define their antibacterial, antioxidant and cytotoxic activities, and yeast particle encapsulation was investigated for the controlled release of bioactive terpenes.
    Schlagwort(e): monoterpenes ; mastiha oil ; absorption ; Citrus limon (L.) Osbeck ; essential oil ; citral ; nutraceuticals ; inflammation ; oxidative stress ; terpenes ; yeast particles ; antimicrobial ; anthelmintic ; prodrug ; beverages ; Citrus ; coumarins ; furocoumarins ; polymethoxyflavones ; linear retention indices ; liquid chromatography ; tandem mass spectrometry ; multiple reaction monitoring ; quality control ; Backhousia citriodora ; lemon myrtle ; lemon oils ; geranial ; neral ; iso-citrals ; citronellal ; flavor ; fragrance ; biological activity ; Lavandula angustifolia ; Rosmarinus officinalis ; essential oils ; hydrolates ; chemical analysis ; volatile compounds ; phytochemicals ; synergism ; fractional inhibitory concentration ; insect mortality rate ; phytopathogenic fungi ; insect pests ; pesticide resistance ; fungicide resistance ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
    Sprache: Englisch
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  • 52
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-02-01
    Beschreibung: This book is relevant to architects, urban designers, planners, and policy makers concerned with enhancing climate-sensitive urban form and planning. It discusses building and neighborhood design: layout and design features that maximize energy efficiency and thermal comfort without compromising the ability of other buildings to enjoy similar benefits; the use of interstitial spaces (piazzas, streets, and parks) to improve the microclimate at the neighbourhood-level; design intervention case studies; innovative uses of interstitial spaces to improve the local climate at the neighborhood level; and urban radiative cooling solutions to mitigate the unintended climate consequences of urban growth and suggestions for ways forward.
    Schlagwort(e): cooling effect ; urban park ; thermal comfort ; physiological equivalent temperature ; perceived thermal comfort ; urban heat island ; air temperature ; sustainable cities ; smart cities ; urban health ; global warming ; urban green spaces ; sustainable urban development ; climate change mitigation and adaptation ; urban resilience  ; heatwaves ; urban overheating ; urban heat island intensity ; energy budget equation ; sensible heat flux ; latent heat flux ; advective heat flux ; Australian climatic conditions ; coastal cities ; desert climate ; surface urban heat island effect ; land use/land cover ; partial least square regression ; nonlinear programming ; Shanghai ; China ; urban form ; urban microclimate design ; city ; sustainability ; sustainable development ; cool roof ; passive radiative cooling ; metamaterials ; prototype ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHH Thermodynamics & heat
    Sprache: Englisch
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  • 53
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: 〈P〉In der Reihe 〈I〉Slavistische Beiträge〈/I〉 werden vor allem slavistische Dissertationen des deutschsprachigen Raums sowie vereinzelt auch amerikanische, englische und russische publiziert. Darüber hinaus stellt die Reihe ein Forum für Sammelbände und Monographien etablierter Wissenschafter/innen dar.〈/P〉
    Schlagwort(e): Funktion ; historicum ; Linguistik ; Panzer ; Philologie ; Praesens ; Russischen ; Russland ; Slavische Sprachwissenschaft ; Sprachwissenschaft ; Verbalaspekts ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 54
    Publikationsdatum: 2024-04-05
    Beschreibung: In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system.
    Schlagwort(e): RC321-571 ; Q1-390 ; Nervous System ; Ion Channels ; Interactome ; cellular signaling ; Protein complexes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 55
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: The series Lectures and Treatises on Slavic Studies, which has been published since 1980, offers opportunities for publication, especially for smaller monographs, which, in terms of their scope, are located between the journal article and the large book. It will cover topics from the whole area of ​​Slavic languages, literatures and cultures as well as their interrelations. In addition to investigations, bibliographies, research reports and editions are published. The authors of the previous volumes come from America, Canada, Germany, Finland, Poland, Russia, Switzerland, Slovenia, the Czech Republic and Hungary.
    Beschreibung: Die seit 1980 erscheinende Reihe Vorträge und Abhandlungen zur Slavistik bietet Publikationsmöglichkeiten vor allem für kleinere Monographien, die ihrem Umfang nach zwischen Zeitschriftenbeitrag und großem Buch anzusiedeln sind. Aufgenommen werden Themen aus dem Gesamtbereich der slavischen Sprachen, Literaturen und Kulturen sowie ihrer Wechselbeziehungen. Neben Untersuchungen werden auch Bibliographien, Forschungsberichte und Editionen veröffentlicht. Die Autoren und Autorinnen der bisherigen Bände kommen aus Amerika, Kanada, Deutschland, Finnland, Polen, Rußland, Schweiz, Slowenien, Tschechische Republik und Ungarn.
    Schlagwort(e): 1885 ; 1898 ; Bondarev ; Briefe ; Donskov ; Erinnerungen ; Literaturwissenschaft ; Perepiska ; Russland ; Tagebücher ; Tolstoj ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 56
    Publikationsdatum: 2024-04-05
    Beschreibung: Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.
    Schlagwort(e): QH426-470 ; Q1-390 ; Regional heritability ; prostate cancer ; infectious diseases ; MCMC ; combining studies screening ; conditional-logistic linkage ; Informatics ; autism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
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  • 57
    Publikationsdatum: 2022-01-31
    Beschreibung: This eBook presents illustrative examples of genetic chaperonopathies affecting primarily nerves and muscles and discusses molecular mechanisms and treatment targeting chaperones, i.e., chaperonotherapy.
    Schlagwort(e): Q1-390 ; small-Hsp ; Hsp60/CCT/BBS ; Indirect/Secondary Chaperonopathies ; Genetic Chaperonopathies ; Hsp40/DnaJ ; chaperonotherapy
    Sprache: Englisch
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  • 58
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    Firenze University Press
    Publikationsdatum: 2024-03-24
    Beschreibung: Ancient linguistic reflection in India was able to combine the analysis of Sanskrit with the awareness that the language through which this analysis is conducted (Sanskrit) is different from the object it examines. Although this language-tool finds its dimension in the artificial Sanskrit of the sütras - the aphorisms of Påñini's grammar - metalinguistic discourse is not restricted to specialized discourse: common speech abounds in metalinguistic notations. The present work focuses on the testimonies of the grammatical school of Pâininian origin, by trying to retrace the course by which metalanguage left the field of naive linguistics to become an object of the school.
    Schlagwort(e): Lingua sanscrita ; Linguistica ; Cultura indiana ; India ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDH Philosophical traditions and schools of thought ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs
    Sprache: Italienisch
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  • 59
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Virus-caused asthma, we now call a phenotype of asthma. Regardless of the significance and popularity of this disease, the etiology of the virus-induced asthma have not well understood. In addition, a few effective vaccines have been applied to prevent respiratory virus infection. To solve the issues, it is essential to clarify and delineate both aspects of the virus and host defense systems including acute/chronic inflammation and airway tissue remodeling. To deeply review and discuss pathophysiology and epidemiology of virus-induced asthma, this topics includes new findings of the host immunity, pathology, epidemiology, and virology of asthma/chronic obstructive pulmonary disease (COPD). We believe that these works are well summarized and informative to glimpse the field of virus- associated asthma and COPD, and may help understanding the basic and clinical aspects of the diseases.
    Schlagwort(e): QR1-502 ; QK1-989 ; Q1-390 ; virus-induced asthma ; Pathology ; respiratory virus ; human immunity ; Epidemiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Sprache: Englisch
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  • 60
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Transfer cells are anatomically specialized cells optimized to support high levels of nutrient transport in plants. These cells trans-differentiate from existing cell types by developing extensive and localized wall ingrowth labyrinths to amplify plasma membrane surface area which in turn supports high densities of membrane transporters. Unsurprisingly, therefore, transfer cells are found at key anatomical sites for nutrient acquisition, distribution and exchange. Transfer cells are involved in delivery of nutrients between generations and in the development of reproductive organs and also facilitate the exchange of nutrients that characterize symbiotic associations. Transfer cells occur across all taxonomic groups in higher plants and also in algae and fungi. Deposition of wall ingrowth-like structures are also seen in “syncytia” and “giant cells” which function as feeding sites for cyst and root-knot nematodes, respectively, following their infection of roots. Consequently, the formation of highly localized wall ingrowth structures in diverse cell types appears to be an ancient anatomical adaption to facilitate enhanced rates of apoplasmic transport of nutrients in plants. In some systems a role for transfer cells in the formation of an anti-pathogen protective barrier at these symplastic discontinuities has been inferred. Remarkably, the extent of cell wall ingrowth development at a particular site can show high plasticity, suggesting that transfer cell differentiation might be a dynamic process adapted to the transport requirements of each physiological condition. Recent studies exploiting different experimental systems to investigate transfer cell biology have identified signaling pathways inducing transfer cell development and genes/gene networks that define transfer cell identity and/or are involved in building the wall ingrowth labyrinths themselves. Further studies have defined the structure and composition of wall ingrowths in different systems, leading in many instances to the conclusion that this process may involve previously uncharacterized mechanisms for localized wall deposition in plants. Since transfer cells play important roles in plant development and productivity, the latter being relevant to crop yield, especially so in major agricultural species such as wheat, barley, soybean and maize, understanding the molecular and cellular events leading to wall ingrowth deposition holds exciting promise to develop new strategies to improve plant performance, a key imperative in addressing global food security. This Research Topic presents a timely and comprehensive treatise on transfer cell biology to help define critical questions for future research and thereby generating a deeper understanding of these fascinating and important cells in plant biology.
    Schlagwort(e): QK1-989 ; Q1-390 ; Wall ingrowth ; Arabidopsis thaliana ; synctial cells ; Zea mays ; transfer cells ; endosperm transfer cells ; Giant Cells ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Sprache: Englisch
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  • 61
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Research during the past decade highlights the strong link between appetitive feeding behavior, reward and motivation. Interestingly, stress levels can affect feeding behavior by manipulating hypothalamic circuits and brain dopaminergic reward pathways. Indeed, animals and people will increase or decrease their feeding responses when stressed. In many cases acute stress leads to a decrease in food intake, yet chronic social stressors are associated to increases in caloric intake and adiposity. Interestingly, mood disorders and the treatments used to manage these disorders are also associated with changes in appetite and body weight. These data suggest a strong interaction between the systems that regulate feeding and metabolism and those that regulate mood. This Research Topic aims to illustrate how hormonal mechanisms regulate the nexus between feeding behavior and stress. It focuses on the hormonal regulation of hypothalamic circuits and/or brain dopaminergic systems, as the potential sites controlling the converging pathways between feeding behavior and stress.
    Schlagwort(e): RC321-571 ; Q1-390 ; stress ; Obesity ; Dopamine ; Ghrelin ; Leptin ; Seasonal regulation ; feeding ; HPA axis ; Hypothalamus ; circadian rhythms ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 62
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-20
    Beschreibung: This Special Issue contains one review and five original articles, all of which address cutting-edge research in the field of water and environmental virology. The review article by Gerba and Betancourt summarizes the current status and future needs for the development of virus detection methods in water reuse systems, especially focusing on methods to assess the infectivity of enteric viruses. Original papers cover a variety of research topics, such as an environmental monitoring survey of group A rotaviruses in sewage and oysters in Japan, the occurrence and genetic diversity of noroviruses and rotaviruses in a wastewater reclamation system in China, the detection of viruses and their indicators in tanker water and its sources in Nepal, integrated culture next-generation sequencing to identify the diversity of F-specific RNA coliphages in wastewater, and the development of a portable collection and detection method for viruses from ambient air and its application to a wastewater treatment plant.
    Schlagwort(e): Q1-390 ; reuse ; aerosols ; viral indicator ; wastewater treatment ; microbial contamination ; index virus ; real-time PCR ; tanker water ; virus ; wastewater reclamation ; pathogenic virus ; infectivity ; chlorination ; molecular methods ; wastewater ; next-generation sequencing ; fecal source tracking ; oyster ; fecal-source marker ; viral contamination ; cell culture ; pathogenic microorganisms ; rotavirus ; ultraviolet disinfection ; F-specific RNA bacteriophage strain ; sewage ; waterborne gastroenteritis viruses ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Englisch
    Format: application/octet-stream
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  • 63
    Publikationsdatum: 2024-04-05
    Beschreibung: euromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
    Schlagwort(e): RC321-571 ; Q1-390 ; Informed Consent ; Deep Brain Stimulation ; Depression ; Neurosurgery ; Movement Disorders ; Neuromodulation ; Enhancement ; Neuroethics ; Philosophy ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 64
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: Germany has gradually become Europe's largest immigration country and is increasingly shaped by the image of a multicultural and multilingual society. However, the issue of multilingualism receives little attention, especially with regard to Slavic migration idioms. The aim of the present study is the empirical investigation of the current language behavior of Slavophone immigrants and the determination of the vitality of their native languages. On the basis of a nationwide survey of 500 immigrants detailed microsociological data on the use of Slavic languages ​​depending on persons, topics and situations will be collected and the influence of linguistic ecological factors such as attitudes, motivations, identity and social network of speakers on language use and language content will be investigated. In addition, on the basis of interdisciplinary approaches to the description of linguistic minorities, the vitality of slavins is analyzed comparatively, showing the current situation and the future development of Slavia in Germany in general and specific tendencies of ethnolects in particular.
    Beschreibung: Deutschland hat sich sukzessive zum größten Einwanderungsland Europas entwickelt und wird immer stärker vom Bild einer multikulturellen und multilingualen Gesellschaft geprägt. Dem Thema Mehrsprachigkeit aber wird insbesondere in Bezug auf slavische Migrationsidiome nur wenig Beachtung geschenkt. Ziel der vorliegenden Studie ist die empirische Erforschung des aktuellen Sprachverhaltens slavophoner Immigranten und die Bestimmung der Vitalität ihrer Muttersprachen. Anhand einer deutschlandweiten Enquete unter 500 Zuwanderern werden detaillierte mikrosoziologische Daten zum Gebrauch der slavischen Sprachen in Abhängigkeit von Personen, Themen und Situationen erhoben und der Einfluss sprachökologischer Faktoren wie Attitüden, Motivationen, Identität und soziales Netzwerk der Sprecher auf die Sprachverwendung und den Spracherhalt untersucht. Zudem wird auf der Grundlage interdisziplinärer Ansätze zur Beschreibung von Sprachminderheiten die Vitalität der Slavinen komparativ analysiert, womit die gegenwärtige Situation und die zukünftige Entwicklung der Slavia in Deutschland im Allgemeinen und spezifische Tendenzen der Ethnolekte im Besonderen aufgezeigt werden.
    Schlagwort(e): Germany ; migration idioms ; immigration ; Achterberg ; Deutschland ; Ethnolinguistischen Vitalität ; Idiome ; Immigrantensprachen ; Immigration nach Deutschland ; Mehrsprachigkeit ; slavischer ; Sprachkontakt ; Vitalität ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 65
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: The integration of multisensory information is an essential mechanism in perception and in controlling actions. Research in multisensory integration is concerned with how the information from the different sensory modalities, such as the senses of vision, hearing, smell, taste, touch, and proprioception, are integrated to a coherent representation of objects. Multisensory integration is central for action control. For instance, when you grasp for a rubber duck, you can see its size and hear the sound it produces. Moreover, identical physical properties of an object can be provided by different senses. You can both see and feel the size of the rubber duck. Even when you grasp for the rubber duck with a tool (e.g. with tongs), the information from the hand, from the effect points of the tool and from the eyes are integrated in a manner to act successfully. Over the recent decade a surge of interest in multisensory integration and action control has been witnessed, especially in connection with the idea that multiple sensory sources are integrated in an optimized way. For this perspective to mature, it will be helpful to delve deeper into the information processing mechanisms and their neural correlates, asking about the range and constraints of this mechanisms, about its localization and involved networks.
    Schlagwort(e): BF1-990 ; Q1-390 ; recalibration ; haptic ; Human Information Processing ; Vision ; Perception ; reference frame ; Acoustics ; Tool Use ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 66
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    transcript Verlag | transcript Verlag
    Publikationsdatum: 2024-03-24
    Beschreibung: Das Einüben der Fähigkeit, mit sprachlicher und kultureller Vielfalt produktiv umzugehen, ist ein Kernanliegen des zeitgemäßen Fremdsprachenunterrichts. Doch wie ist der Umgang mit dieser im Klassenzimmer organisiert? Daniel H. Rellstab analysiert auf der Basis eines von Erving Goffman geprägten Interaktionsverständnisses Interaktionen in »Deutsch als Fremdsprache«-Klassenzimmern. Dabei zeigt er, welche Ressourcen Lehrkräfte sowie Schülerinnen und Schüler in der Interaktion einsetzen, wie sie aushandeln, welche Sprachen legitim, welche illegitim sind, und wie sie dabei Identitäten und Normen re- und dekonstruieren.
    Schlagwort(e): Deutsch Als Fremdsprache ; Interaktion ; Interaktionsanalyse ; Multimodalität ; Mehrsprachigkeit ; Legitimität ; Sprachkompetenz ; Spracherwerb ; Didaktik ; Lernen ; Identität ; Normensystem ; Sprache ; Bildung ; Gesellschaft ; Sprachwissenschaft ; Interkulturalität ; Germanistik ; Bildungsforschung ; Pädagogik ; German As a Foreign Language ; Interaction ; Interaction Analysis ; Multimodality ; Multilinguism ; Legitimacy ; Language Competence ; Language Acquisition ; Didactics ; Learning ; Identity ; Standard System ; Language ; Education ; Society ; Linguistics ; Interculturalism ; German Literature ; Educational Research ; Pedagogy ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general
    Sprache: Deutsch
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  • 67
    Publikationsdatum: 2024-04-05
    Beschreibung: Volume I, entitled “Augmentation of Brain Functions: Brain-Machine Interfaces”, is a collection of articles on neuroprosthetic technologies that utilize brain-machine interfaces (BMIs). BMIs strive to augment the brain by linking neural activity, recorded invasively or noninvasively, to external devices, such as arm prostheses, exoskeletons that enable bipedal walking, means of communication and technologies that augment attention. In addition to many practical applications, BMIs provide useful research tools for basic science. Several articles cover challenges and controversies in this rapidly developing field, such as ways to improve information transfer rate. BMIs can be applied to the awake state of the brain and to the sleep state, as well. BMIs can augment action planning and decision making. Importantly, BMI operations evoke brain plasticity, which can have long-lasting effects. Advanced neural decoding algorithms that utilize optimal feedback controllers are key to the BMI performance. BMI approach can be combined with the other augmentation methods; such systems are called hybrid BMIs. Overall, it appears that BMI will lead to many powerful and practical brain-augmenting technologies in the future.
    Schlagwort(e): RC321-571 ; Q1-390 ; microcircuits ; Brain machine interface (BMI) ; nootropics ; tDCStranscranial direct current stimulation ; neural networks ; neuroprosthesis ; TMS ; implants ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 68
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-05-06
    Beschreibung: This reprint is devoted to “greener catalysis for environmental applications”, and primarily covers the catalytic synthesis of value-added chemicals, as well as the catalytic removal of pollutants. The most important topics covered were the conversion of waste to the product, solvent-free conditions as well as toxicity assessment of the reaction products.
    Schlagwort(e): selectivity tuning ; CO2 methanation ; reverse water gas shift ; photocatalysis ; dye ; UV ; peroxydisulfate ; advanced oxidation process ; Fischer-Tropsch ; jet fuel ; gasoline ; CoMn ; hydrotalcite-like precursors ; heterogeneous catalysis ; montmorillonite ; benzimidazoles ; gallium ; vanadium ; hydrodesulfurization ; hydrogenation ; synthesis method ; catalysis ; zero valent iron ; de-chlorination ; borohydride ; sol-gel ; ferromagnetic ; glycine–nitrate process ; copper-based nanoparticles ; photocatalysis activity ; NP9EO ; Fenton degradation ; ofloxacin ; Fe3O4 ; zeolite ; heterogeneous ; ion exchange resins ; waste cooking oil ; reuse of catalyst ; epoxidation ; Circular Economy ; contaminants of emerging concern ; advanced oxidation processes ; by-products ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
    Sprache: Englisch
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  • 69
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2022-12-06
    Beschreibung: Vegetable crops provide valuable minerals and vitamins that are indispensible for human health. Scientists have been working on the genetics of vegetable crops, deciphering the molecular bases of agronomically important traits. These genetic bases and variations in vegetable traits will greatly facilitate vegetable genetic improvement. Therefore, the genes of and genetic research on vegetable crops are of great importance. This Special Issue is a collection of 13 important research papers addressing the genes, genetics, and breeding of major vegetable crops. In the present book, the authors described the genes and QTLs responsible for stress tolerance, disease resistance, vegetable yield, and quality. The 13 research papers cover germplasm enhancement and evaluation, QTL mapping, gene isolation, marker development, and gene expression as well as gene editing in a wide range of vegetable species, including broccoli, pepper, eggplant, onion, and Cucurbita species. Readers from all over the globe are expected to greatly benefit from this Special Issue collection regarding their own work and the goal of improving breeding efficiency with molecular breeding to generate environment-adaptive, high-yield, and high-quality vegetable crops with which to feed the global population of 9.7 billion in an extreme climate by 2050.
    Schlagwort(e): pepper ; Capsicum annuum ; Phytophthora capsici ; high-density genetic map ; QTL ; Capcicum annuum L. ; RNA-Seq ; nitrogen-use efficiency ; low-nitrogen tolerance ; CaHSP18.1a ; gene silencing ; transgenic Arabidopsis ; heat stress ; gene expression ; pumpkin ; simple sequence repeat (SSR) ; syntenic relationship ; cross-species markers ; population structure ; eggplant ; heat shock factor (Hsf) ; heat shock protein (Hsp) ; thermotolerance ; C. frutescens ; SSR ; germplasm ; genetic diversity ; CRISPR/Cas ; gene knockout ; genome editing ; germplasm resource ; precision editing ; regulatory framework ; trait improvement ; Brassica oleracea ; broccoli ; candidate gene ; anthocyanin ; allelochemicals ; VOCs properties ; VOCs action ; VOCs detection ; green agriculture ; progress ; genetic researches ; molecular breeding ; transcriptomics ; transcription factor ; heritability ; genetic advance ; multi-trait selection ; principal component analysis ; HRM ; molecular marker ; phylogenetic analysis ; RNA sequencing ; SCAR ; SNP ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
    Sprache: Englisch
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  • 70
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    Taylor & Francis | A Global History of Ideas in the Language of Law | Language and Law | Routledge
    Publikationsdatum: 2024-03-24
    Beschreibung: Language plays an essential role both in creating law and in governing its implementation. Providing an accessible and comprehensive introduction to this subject, Language and Law:describes the different registers and genres that make up spoken and written legal language and how they develop over time; analyses real-life examples drawn from court cases from different parts of the world, illustrating the varieties of English used in the courtroom by speakers occupying different roles; addresses the challenges presented to our notions of law and regulation by online communication; discusses the complex role of translation in bilingual and multilingual jurisdictions, including Hong Kong and Canada; and provides readings from key scholars in the discipline, including Lawrence Solan, Peter Goodrich, Marianne Constable, David Mellinkoff, and Chris Heffer. With a wide range of activities throughout, this accessible textbook is essential reading for anyone studying language and law or forensic linguistics.
    Schlagwort(e): English for law ; English for specific purposes law ; forensic linguistics ; language and the law ; legal English ; legal genres ; thema EDItEUR::C Language and Linguistics::CB Language: reference and general ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFB Sociolinguistics ; thema EDItEUR::L Law::LA Jurisprudence and general issues ; thema EDItEUR::L Law::LA Jurisprudence and general issues::LAR Legal aspects of criminology ; thema EDItEUR::L Law::LA Jurisprudence and general issues::LAS Legal skills and practice
    Sprache: Englisch
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  • 71
    Publikationsdatum: 2024-04-05
    Beschreibung: Photosystem II is a 700-kDa membrane-protein super-complex responsible for the light-driven splitting of water in oxygenic photosynthesis. The photosystem is comprised of two 350-kDa complexes each made of 20 different polypeptides and over 80 co-factors. While there have been major advances in understanding the mature structure of this photosystem many key protein factors involved in the assembly of the complex do not appear in the holoenzyme. The mechanism for assembling this super-complex is a very active area of research with newly discovered assembly factors and subcomplexes requiring characterization. Additionally the ability to split water is inseparable from light-induced photodamage that arises from radicals and reactive O2 species generated by Photosystem II chemistry. Consequently, to sustain water splitting, a “self repair” cycle has evolved whereby damaged protein is removed and replaced so as to extend the working life of the complex. Understanding how the biogenesis and repair processes are coordinated is among several important questions that remain to be answered. Other questions include: how and when are the inorganic cofactors inserted during the assembly and repair processes and how are the subcomplexes protected from photodamage during assembly? Evidence has also been obtained for Photosystem II biogenesis centers in cyanobacteria but do these also exist in plants? Do the molecular mechanisms associated with Photosystem II assembly shed fresh light on the assembly of other major energy-transducing complexes such as Photosystem I or the cytochrome b6/f complex or indeed other respiratory complexes? The contributions to this Frontiers in Plant Science Research Topic are likely to reveal new details applicable to the assembly of a range of membrane-protein complexes, including aspects of self-assembly and solar energy conversion that may be applied to artificial photosynthetic systems. In addition, a deeper understanding of Photosystem II assembly — particularly in response to changing environmental conditions — will provide new knowledge underpinning photosynthetic yields which may contribute to improved food production and long-term food security.
    Schlagwort(e): QK1-989 ; Q1-390 ; Arabidopsis thaliana ; photoactivation ; photosynthesis ; Chlamydomonas reinhardtii ; cyanobacteria ; biogenesis ; Photosystem II ; photodamage ; Nicotiana tabacum ; Synechocystis sp. PCC 6803 ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Sprache: Englisch
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  • 72
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: Big data is revolutionizing our ability to measure and study the human brain. New technology increases the resolution of images that are being study as well as enables researchers to study the brain as it functions. These technological advances are combined with efforts to collect neuroimaging data on large numbers of subjects, in some cases longitudinally. This combination of advances in measurement and scope of studies requires novel development in the statistical analysis. Fast, scalable, robust and accurate models and approaches need to be developed to make headway on these problems. This volume represents a unique collection of researchers providing deep insights on the statistical analysis of big neuroimaging data.
    Schlagwort(e): RC321-571 ; Q1-390 ; fMRI ; Neuroscience ; functional connectivity ; EEG ; Classification ; prediction ; big data ; MEG ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 73
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    De Gruyter | De Gruyter
    Publikationsdatum: 2024-03-24
    Beschreibung: This ambitious study of the proper names of the Chanson de Roland proves that it is more tightly and profoundly structured and considerably richer in depicting reality than generally assumed, and that its prehistory can be traced back (almost) to the Frankish defeat. Paris and Bédier were right on the main point close to their hearts: the song has both the thoroughly sophisticated structure (Bédier) and the imposingly long prehistory (Paris).
    Schlagwort(e): Chanson de Roland ; Onomastics ; Epic Poem ; Medieval French Literature ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFF Historical and comparative linguistics ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general::DSBB Literary studies: ancient, classical and medieval
    Sprache: Englisch
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  • 74
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: A conversation between two people can only take place if the words intended by each speaker are successfully recognized. Spoken word recognition is at the heart of language comprehension. This automatic and smooth process remains a challenge for models of spoken word recognition. Both the process of mapping the speech signal onto stored representations for words, and the format of the representation themselves are subject to debate. So far, existing research on the nature of spoken word representations has focused mainly on native speakers. The picture becomes even more complex when looking at spoken word recognition in a second language. Given that most of the world’s speakers know and use more than one language, it is crucial to reach a more precise understanding of how bilingual and multilingual individuals encode spoken words in the mental lexicon, and why spoken word recognition is more difficult in a second language than in the native language. Current models of native spoken word recognition operate under two assumptions: (i) that listeners’ perception of the incoming speech signal is optimal; and (ii) that listeners’ lexical representations are accurate. As a result, lexical representations are easily activated, and intended words are successfully recognized. However, these assumptions are compromised when applied to a later-learned second language. For a variety of reasons (e.g., phonetic/phonological, orthographic), second language users may not perceive the speech signal optimally, and they may still be refining the motor routines needed for articulation. Accordingly, their lexical representations may differ from those of native speakers, which may in turn inhibit their selection of the intended word forms. Second language users also have to solve a larger selection challenge—having words in more than one language to choose from. Thus, for second language users, the links between perception, lexical representations, orthography, and production are all but clear. Even for simultaneous bilinguals, important questions remain about the specificity and interdependence of their lexical representations and the factors influencing cross-language word activation. This Frontiers Research Topic seeks to further our understanding of the factors that determine how multilinguals recognize and encode spoken words in the mental lexicon, with a focus on the mapping between the input and lexical representations, and on the quality of lexical representations.
    Schlagwort(e): BF1-990 ; Q1-390 ; Phonological knowledge ; Second-language speech ; bilingual and bidialectal lexicon ; spoken word recognition ; lexical access ; orthographic knowledge ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 75
    Publikationsdatum: 2024-03-31
    Beschreibung: This forum of comprehensive reviews and research studies on distinct aspects of the pathophysiology of BAV aortopathy provides both the state of the art in the knowledge on this complex disease and novel insights into its causes and consequences. The present collection of focused papers also envisions and proposes new therapeutic strategies, novel biomarkers and original risk stratification criteria, for the improvement of patient management.
    Schlagwort(e): QP1-981 ; Q1-390 ; smooth muscle cells ; microRNAs ; aortic root ; endothelial cells ; aortic surgery ; bicuspid aortic valve ; 4DFlow analysis ; aortopathy ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Sprache: Englisch
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  • 76
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: This research topic stems from the "Interdisciplinary Approaches to Multilingualism" conference, which was hosted by the Language Research Centre at the University of Calgary. It was the first conference of its kind, which brought together the work of researchers, educators, and policy makers in the areas of first and second language acquisition from psycholinguistic and pedagogical perspectives. The goal was to provide an opportunity for participants to engage with the implications of multilingualism from a range of perspectives, including the effects of being bilingual from infancy to adulthood, the process and benefits of learning multiple languages, and the impact of multilingualism on society.
    Schlagwort(e): BF1-990 ; Q1-390 ; Developmental psycholinguistics ; second language literacy development ; Multilingualism ; psycholinguistic research methods ; Second language pedagogy ; bilingualism ; Second Language Acquisition ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 77
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 78
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    Frontiers Media SA
    Publikationsdatum: 2024-04-05
    Beschreibung: In the last decade, sleep spindles have attracted steadily increasing attention. This interest is motivated by the many intriguing relationships between spindles and various diseases (e.g., schizophrenia, Parkinson, Alzheimer, autism, mental retardation), recovery processes (e.g., post brain stroke), and cognitive faculties (e.g., memory consolidation, intelligence, dream recall, sleep preservation). Nonetheless, a methodological wall has impeded the study of sleep spindles. Their investigation rests heavily on our ability to reliably and consistently identify spindle patterns from background EEG activity, a task involving many obstacles, including: a fuzzy definition of spindles, low inter-expert agreement on their scoring, lack of consensus on standard techniques for their automated detection, low reproducibility of observed characteristics and correlates, unavailability of large, standardized, high-quality databases, and inconsistencies in the methods used to evaluate the performance of automated detectors. The primary aims of this research topic were to bring together world-class researchers on a project designed to facilitate exchanges on methodological difficulties encountered in assessing sleep spindles and to promote standardized spindle-related resources. In preparing their contributions, authors were encouraged to use existing – or to propose new – publicly available resources for assessing sleep spindles. To allow fair and accurate comparison of reported results, the authors were also encouraged to validate their tools on a common benchmark. A database containing expert spindle scoring (i.e., the Montreal Archive of Sleep Studies) was made publicly available for that purpose.
    Schlagwort(e): RC321-571 ; Q1-390 ; Neural oscillations ; Electroencephalography (EEG) ; Sleep ; Sleep Spindles ; Memory ; IQ ; sigma waves ; automatic detection ; biomarker ; Open access ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Sprache: Englisch
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  • 79
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    Frontiers Media SA
    Publikationsdatum: 2024-03-31
    Beschreibung: Energy metabolism is central to life and altered energy expenditure (EE) is often cited as a central mechanism responsible for development of the obese phenotype. Resting EE, EE of physical activity, cold induced thermogenesis and thermic effect of feeding add to produce total EE but can also affect each other. It is thus very important that each component be well measured. Measuring energy expenditure by indirect calorimetry is extremely simple in theory but the practice if far more difficult. Taking into account temperature in small sized animals, measuring accurately the effect of activity on EE, correcting EE for body size body composition, age sex etc… add difficulties in producing reliable data. The goal of this Research Topic was to call for the practical experience of main investigators trained to practice calorimetry in order to get their feedback and the way they deal with the various and specific problems of humans and animal calorimetry. The goal is to share the questions/solutions experienced by the contributors to inititate a “guide of the good practices” that can be periodically updated and used by all those who are and will be interested in measuring energy metabolism from the 20g mouse to the human and large farm animals.
    Schlagwort(e): QP1-981 ; Q1-390 ; Body Composition ; Thermogenesis ; brown adipose tissue ; Body Size ; Energy Expenditure ; indirect calorimetry ; physical activity ; metabolic Phenotyping ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Sprache: Englisch
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  • 80
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    Language Science Press | Language Science Press
    Publikationsdatum: 2024-03-24
    Beschreibung: This grammar offers a grammatical description of the Ngòló variety of Gyeli, an endangered Bantu (A80) language spoken by 4,000-5,000 "Pygmy" hunter-gatherers in southern Cameroon. It represents one of the most comprehensive descriptions of a northwestern Bantu language. The grammatical description, which is couched in a form-to-function approach, covers all levels of language, ranging from Gyeli phonology to its information structure and complex clauses. It draws on nineteen months of fieldwork carried out as part of the "Bagyeli/Bakola" DoBeS (Documentation of Endangered Languages) project between 2010 and 2014. The resulting multimodal corpus from that project, which includes texts of diverse genres such as traditional stories, narratives, multi-party conversations and dialogues, procedural texts, and songs, provides the empirical basis for the grammatical description. The documentary text collection, supplemented by data from elicitation work, questionnaires, and experiments, are accessible in the Bagyeli/Bakola collection of The Language Archive. With additional ethnographic, sociolinguistic, diachronic, and comparative remarks, the grammar may appeal to a wider audience in general linguistics, typology, Bantu studies, and anthropology. In 2019, the grammar received the Pāṇini Award by the Association for Linguistic Typology.
    Schlagwort(e): Language Arts & Disciplines ; Linguistics ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
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  • 81
    Publikationsdatum: 2023-12-20
    Beschreibung: Landscapes have long been viewed as ‘multifunctional’, integrating ecological, economic, sociocultural, historical, and aesthetic dimensions. Landscape science and public awareness in Europe have been progressing in leaps and bounds. The challenges involved in landscape-related issues and fields, however, are multiple and refer to landscape stewardship and protection, as well as to the development of comprehensive theoretical and methodological approaches, in tandem with public sensitization and participatory governance and in coordination with appropriate top-down planning and policy instruments. Landscape-scale approaches are fundamental to the understanding of past and present cultural evolution, and are now considered to be an appropriate spatial framework for the analysis of sustainability. Methods and tools of landscape analysis and intervention have also gone a long way since their early development in Europe and the United States. Although significant progress has been made, there remain many issues which are understudied or not investigated at all—at least in a Mediterranean context. This Special Issue addresses the application of landscape theory and practice in the Eastern Mediterranean and mainly, but not exclusively, reports on the outcomes of an international conference held in Jordan, in December 2015, with the title “Landscapes of Eastern Mediterranean: Challenges, Opportunities, Prospects and Accomplishments”. The focus of this Special Issue, landscapes of the Eastern Mediterranean region, thus constitutes a timely area of research interest, not only because these landscapes have so far been understudied, but also as a rich site of strikingly variegated, long-standing multicultural human–environmental interactions. These interactions, resting on and taking shape through millennia of continuity in tradition, have been striving to adapt to technological advances, while currently juggling with manifold and multilayered socioeconomic and climate–environmental crises.
    Schlagwort(e): G1-922 ; Q1-390 ; n/a ; landscape archaeology ; Cyprus ; Landscape Character Assessment (LCA) ; Eastern Mediterranean ; Land Description Units ; stakeholders’ analysis ; UK ; local authority ; ancient sanctuaries ; East Med landscape ; Twain-born Border Lord ; Landscape Decision Support System ; mapping ; topography ; Byzantine landscape and garden art ; economy ; LCA ; classification ; churches ; Arabic-speaking ; participatory ; Landscape Risk Assessment Model ; landforms ; GIS ; planning ; typology ; Greek-speaking ; public realm ; landscape changes ; sacred space ; comparative study ; urban environment ; ideology ; political power ; Arabic landscape and garden art ; cultural sustainability ; historical maps ; religion ; rural land ; multi-functional landscapes ; Lebanon ; Mediterranean ; geographical information system ; spatial distributions ; Land Description Unit (LDU) ; political sustainability ; landscape ; landscape character assessment ; governance ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Sprache: Englisch
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  • 82
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-03-07
    Beschreibung: Metal 3D printing, as an advanced forming, can manufacture parts directly from digital model by using layer by layer material build-up approach. This manufacturing method can prepare complex shape metal parts in short time, with and high precision. Three-dimensional printing processes can be classified into two major groups: Powder Bed Fusion-based technologies and Directed Energy Deposition. Three-dimensional printing features freedom of part complexity, part design, and light-weighting for aerospace, automobile, and other industries application. The Global Metal 3D Printing Market is mainly driven by the the fast developing of aerospace and automobile industry. The Global Metal 3D Printing Market size was valued at USD 534.18 Million in 2020 and is projected to reach USD 4458.76 Million by 2028, growing at a CAGR of 30.38% from 2021 to 2028.
    Schlagwort(e): 17-4PH ; SLM ; solution temperature ; microstructure and properties ; selective laser melting ; CuCrZr alloy ; process parameters ; relative density ; tensile properties ; Ni-based superalloys ; electron beam melting ; additive manufacturing ; Argon gas atomized ; plasma rotation electrode process ; powder characteristics ; residual stresses ; selective laser melting (SLM) ; finite element modeling (FEM) ; triply periodic minimal surface (TPMS) ; copper corrosion ; liquefied petroleum gas ; H2S corrosion ; SEM ; XPS ; CLF-1 steel ; microstructure ; mechanical properties ; in-situ alloying ; composition inhomogeneity ; computer simulation ; processing map ; laser powder bed fusion ; graphene ; high temperature ; mechanical property ; alumina ; cobalt-chromium-molybdenum alloy ; electroless plating ; friction performance ; implants ; Laser Powder Bed Fusion ; defects ; process parameter ; powder bed fusion ; surface roughness ; porosity ; residual stress ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
    Sprache: Englisch
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  • 83
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    Language Science Press
    Publikationsdatum: 2024-03-24
    Beschreibung: Roots of language was originally published in 1981 by Karoma Press (Ann Arbor). It was the first work to systematically develop a theory first suggested by Coelho in the late nineteenth century: that the creation of creole languages somehow reflected universal properties of language. The book also proposed that the same set of properties would be found to emerge in normal first-language acquisition and must have emerged in the original evolution of language. These proposals, some of which were elaborated in an article in Behavioral and Brain Sciences (1984), were immediately controversial and gave rise to a great deal of subsequent research in creoles, much of it aimed at rebutting the theory. The book also served to legitimize and stimulate research in language evolution, a topic regarded as off-limits by linguists for over a century. The present edition contains a foreword by the author bringing the theory up to date; a fuller exposition of many of its aspects can be found in the author’s most recent work, More than nature needs (Harvard University Press, 2014).
    Schlagwort(e): pidgin ; creole ; language origins ; language evolution ; Semantics ; Stratum (linguistics) ; Verb ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
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  • 84
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-03-07
    Beschreibung: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Schlagwort(e): 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Sprache: Englisch
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  • 85
    Publikationsdatum: 2023-12-21
    Beschreibung: Aflatoxins are a group of polyketide mycotoxins that are produced mainly by members of the genus Aspergillus. Production of these toxic secondary metabolites is closely related to fungal development (Keller et al., 2005; Jamali et al., 2012). Contamination of food, feed and agricultural commodities by aflatoxins poses enormous economic and serious health concerns because these chemicals are highly carcinogenic and can directly influence the structure of DNA. The resulting genetic defects can lead to fetal misdevelopment and miscarriages; aflatoxins are also known to suppress immune systems (Razzaghi-Abyaneh et al., 2013). In a global context, aflatoxin contamination is a constant concern between the 35N and 35S latitude where developing countries are mainly situated. With expanding boundaries of developing countries, aflatoxin contamination has become a persistent problem to those emerging areas (Shams-Ghahfarokhi et al., 2013). The continuing threat by aflatoxin contamination of food, feed and agricultural commodities to the world population has made aflatoxin research one of the most exciting and rapidly developing study areas of microbial toxins. The present research topic includes six review articles, three mini reviews and four original research articles. Contributors highlight current global health issues arising from aflatoxins and aflatoxigenic fungi and cover important aspects of aflatoxin research including contamination of crops, epidemiology, molecular biology and management strategies. Special attention is given to fungus-plant host interactions, biodiversity and biocontrol, sexual recombination in aflatoxigenic aspergilli, potential biomarkers for aflatoxin exposure in humans and safe storage programs.
    Schlagwort(e): R5-920 ; QR1-502 ; Q1-390 ; TX341-641 ; genetic diversity ; Public Health ; Aspergillus flavus ; Genomics ; MicroRNAs ; Fungus host interactions ; biological control ; aflatoxin ; agricultural crops ; bic Book Industry Communication::M Medicine
    Sprache: Englisch
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  • 86
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    De Gruyter | De Gruyter
    Publikationsdatum: 2024-03-26
    Beschreibung: This book explores the history of literature as a history of changing media and modes of communication, from manuscript to print, from the codex to the computer, and from paper to digital platforms. It argues that literature has evolved, and continues to evolve, in sync with material forms and formats that engage our senses in multiple ways. Because literary experiences are embedded in, and enabled by, media, the book focuses on literature as a changing combination of material and immaterial features. The principal agents of this history are no longer genres, authors, and texts but configurations of media and technologies. In telling the story of these combinations from prehistory to the present, Ingo Berensmeyer distinguishes between three successive dominants of media usage that have shaped literary history: performance, representation, and connection. Using English literature as a test case for a long view of media history, this book combines an unusual bird’s eye view across periods with illuminating readings of key texts. It will prove an invaluable resource for teaching and for independent study in English or comparative literature and media studies.
    Schlagwort(e): Media ; literature ; history ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCT Media studies
    Sprache: Englisch
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  • 87
    Publikationsdatum: 2024-04-05
    Beschreibung: Helicases are the proteins that bind to double- or single-stranded DNA and/or RNA chains to unwind higher order structures, usually consuming energy from the hydrolysis of ATP molecules. The biological roles of helicases are associated with a variety of DNA and/or RNA metabolisms, including DNA-replication, -repair, -recombination, RNA processing, and transcription. Dysfunctions of helicases cause various diseases, such as xeroderma pigmentosum (XP), premature aging syndrome, cancer and immunodeficiency, in humans. Moreover, recent genetic analyses revealed that mutations in helicase-encoding genes are frequently found in patients of specific diseases. Some helicases regulate cellular senescence by controlling integrity of genomes, and others play a role in neuromuscular functions presumably by modulating processing of mRNAs. However, the molecular mechanisms of how helicases are regulated in order to maintain our health are not yet fully understood. In this research topic, we will focus on the expression and functions of helicases and their encoding genes, reviewing recent research progresses that provide new insights into development of clinical and pharmaceutical treatments targeting helicases.
    Schlagwort(e): QH426-470 ; Q1-390 ; DNA Repair ; Aging ; helicases ; Telomere ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
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  • 88
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-20
    Beschreibung: The practical importance of economic valuation information can hardly be overstated. Coastal and marine resource policy planning and management benefit from complete information on the impact of policy decisions.
    Schlagwort(e): Q1-390 ; internet survey ; open access ; contingent valuation method ; coastal management ; tourism ; Thailand ; marine ; wetlands ; harmful algae blooms ; environmental valuation ; quota ; cyanobacteria ; estuarine and coastal ecosystems ; wealth accounting ; seawater quality ; economic analysis ; remote sensing ; ecosystem restoration ; coastal ecosystems ; random utility model ; contingent behavior ; public policy ; habitat–fishery linkages ; Barbados ; coastal ecosystem services valuation ; fishery ; mangroves ; ecosystem services valuation ; coral reefs valuation ; recreational boating ; regulated open access ; non-market value ; economic valuation ; ecosystem services ; coastal ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Sprache: Englisch
    Format: application/octet-stream
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  • 89
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: The aim of this work is to describe dialog structures: dialogue structures that express different attitudes of interlocutors to the conversation and the partner. In addition, however, my hope is to be able to point out a possible way through the description of a dialogical attitude and the corresponding discussion structures, using specific "techniques" so structured and structured conversations that they lead to real understanding and thus to an improvement of the culture of dialogue.
    Beschreibung: Das Ziel dieser Arbeit ist es, Dialogstrukturen zu beschreiben: Dialogstrukturen, die Ausdruck unterschiedlicher Haltungen von Gesprächspartnern zum Gespräch und zum Partner sind. Darüber hinaus jedoch ist meine Hoffnung, durch die Beschreibung einer dialogischen Gesprächshaltung und der entsprechenden Gesprächsstrukturen einen möglichen Weg zu weisen, mittels bestimmter "Techniken" Gespräche so strukturieren und gestalten zu können, daß sie zu wirklichem Verständnis und damit zu einer Verbesserung der Dialogkultur fuhren.
    Schlagwort(e): dialog structures ; basierend ; begründete ; Dialoganalyse ; dialogisch ; Dialogstrukturen ; Eine ; erweiterte ; Gesprächshaltung ; Illokutive ; Linguistik ; narrativen ; neueren ; Prosa ; Scharpenack ; Slavische Sprachwissenschaft ; Sprechakttheorie ; Strukturen ; Tschechische Republik ; tschechischen ; Unrath ; Untersuchungen ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 90
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    Taylor & Francis | Routledge
    Publikationsdatum: 2024-03-24
    Beschreibung: creative texts; translation technologies; machine translation; computer-aided translation; translation practice
    Schlagwort(e): creative texts; translation technologies; machine translation; computer-aided translation; translation practice ; thema EDItEUR::C Language and Linguistics::CB Language: reference and general ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
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  • 91
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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  • 92
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: Die vorliegende Arbeit behandelt die "Unfrisierten Gedanken" von Stanisław Jerzy Lec. Der Untersuchung der Aphorismen Lec' im dritten Kapitel geht eine theoretische Begründung unseres Aphorismusverständnisses im zweiten Kapitel voraus sowie im ersten Kapitel ein Überblick über die Geschichte des Aphorismus in Polen.
    Schlagwort(e): Aphorismus ; Aphoristik ; Gedanken ; Jerzy ; Krupka ; Linguistik ; Literaturwissenschaft ; Philologie ; Platz ; Polen ; polnische ; polnischen ; Sprachwissenschaft ; Stanisław ; Unfrisierten ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 93
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    Frontiers Media SA
    Publikationsdatum: 2024-03-29
    Beschreibung: The visual system consists of hierarchically organized distinct anatomical areas functionally specialized for processing different aspects of a visual object (Felleman & Van Essen, 1991). These visual areas are interconnected through ascending feedforward projections, descending feedback projections, and projections from neural structures at the same hierarchical level (Lamme et al., 1998). Accumulating evidence from anatomical, functional and theoretical studies suggests that these three projections play fundamentally different roles in perception. However, their distinct functional roles in visual processing are still subject to debate (Lamme & Roelfsema, 2000). The focus of this Research Topic is the roles of feedforward and feedback projections in vision. Even though the notions of feedforward, feedback, and reentrant processing are widely accepted, it has been found difficult to distinguish their individual roles on the basis of a single criterion. We welcome empirical contributions, theoretical contributions and reviews that fit into any one (or a combination) of the following domains: 1) their functional roles for perception of specific features of a visual object 2) their contributions to the distinct modes of visual processing (e.g., pre-attentive vs. attentive, conscious vs. unconscious) 3) recent techniques/methodologies to identify distinct functional roles of feedforward and feedback projections and corresponding neural signatures. We believe that the current Research Topic will not only provide recent information about feedforward/feedback processes in vision but also contribute to the understanding fundamental principles of cortical processing in general.
    Schlagwort(e): BF1-990 ; Q1-390 ; projections ; processes ; Feedback ; Vision ; feedforward ; Visual System ; mechanisms ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Sprache: Englisch
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  • 94
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    Language Science Press
    Publikationsdatum: 2024-03-24
    Beschreibung: This book presents groundbreaking robotic experiments on how and why spatial language evolves. It provides detailed explanations of the origins of spatial conceptualization strategies, spatial categories, landmark systems and spatial grammar by tracing the interplay of environmental conditions, communicative and cognitive pressures. The experiments discussed in this book go far beyond previous approaches in grounded language evolution. For the first time, agents can evolve not only particular lexical systems but also evolve complex conceptualization strategies underlying the emergence of category systems and compositional semantics. Moreover, many issues in cognitive science, ranging from perception and conceptualization to language processing, had to be dealt with to instantiate these experiments, so that this book contributes not only to the study of language evolution but to the investigation of the cognitive bases of spatial language as well.
    Schlagwort(e): robotic experiments ; spatial language ; spatial grammar ; Adjective ; Adverb ; Anatomical terms of location ; Chinese grammar ; Evolution ; Frame of reference ; Parsing ; Preposition and postposition ; Semantics ; Syntax ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::U Computing and Information Technology
    Sprache: Englisch
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  • 95
    Publikationsdatum: 2024-03-24
    Beschreibung: 〈P〉This work deals with the morpho-syntactic expansions which occur in translation from English into Slovenian, proceeding from the assumption that such expansions are the most common, "prototypical" response of the translator when faced by an original containing grammatically complex structures.〈/P〉
    Schlagwort(e): Complexity ; Control group ; English ; Expansions ; from ; into ; Milena ; Milojević ; Morpho ; Morpho-syntactic expansions ; non-systemic expansion ; Original ; Prototypical ; Response ; Sheppard ; Slovenian ; Syntactic ; Translation ; translation studiesw ; unit of translation ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
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  • 96
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    Language Science Press | Language Science Press
    Publikationsdatum: 2024-03-24
    Beschreibung: Sanzhi Dargwa belongs to the Dargwa (Dargi) languages (ISO dar; Glottocode sanz1248) which form a subgroup of the East Caucasian (Nakh-Dagestanian) language family. Sanzhi Dargwa is spoken by approximately 250 speakers and is severely endangered. This book is the first comprehensive descriptive grammar of Sanzhi, written from a typological perspective. It treats all major levels of grammar (phonology, morphology, syntax) and also information structure. Sanzhi Dargwa is structurally similar to other East Caucasian languages, in particular Dargwa languages. It has a relatively large consonant inventory including pharyngeal and ejective consonants. Sanzhi morphology is concatenative and mainly suffixing. The language exhibits a mixture of dependent-marking in the form of a rich case inventory and head-marking in the form of verbal agreement. Nouns are divided into three genders. Verbal inflection conflates tense/aspect/mood/evidentiality in a rich array of synthetic and analytic verb forms as well as participles, converbs, a masdar (verbal noun), and infinitive and some other forms used in analytic tenses and subordinate clauses. Salient traits of the grammar are two independently operating agreement systems: gender/number agreement and person agreement. Within the nominal domain, modifiers agree with the head nominal in gender/number. Agreement within the clausal domain is mainly controlled by the argument in the absolutive case. Person agreement operates only at the clausal level and according to the person hierarchy 1, 2 〉 3. Sanzhi has ergative alignment in the form of gender/number agreement and ergative case marking. The most frequent word order at the clause level is SOV, though all other logically possible word orders are also attested. In subordinate clauses, word order is almost exclusively head-final.
    Schlagwort(e): Language Arts & Disciplines ; Linguistics ; General ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Englisch
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  • 97
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    Peter Lang International Academic Publishing Group
    Publikationsdatum: 2024-03-24
    Beschreibung: The aim of this study is to describe and analyze the dual system of the New Testament of Miklavuš Jakubica (1548), because of the Du. a variety of individual studies exist, such. For example, to discuss the numerus category in Slavic in general, general representations of Sorbian with descriptions of dual paradigms, descriptions of individual inflectional paradigms of Ns, their peculiarities and genesis (...). The author sets himself the goal, after some introductory remarks on the translation of the NT by Miklawuš Jakubica in the second chapter, to discuss theoretical foundations of the morphological category, essentially referring to the number in general, the origin of the Du. and its different forms, like natural or free, you. with two and both and anaphoric you. will be received. The investigation is done both from a synchronous and a diachronic point of view, since paradigmatic comparisons with older ns. Grammars as well as with the contemporary language to be drawn.
    Beschreibung: Die vorliegende Untersuchung verfolgt das Ziel, das Dualsystem des Neuen Testaments des Miklawuš Jakubica ( 1548) zu beschreiben und zu analysieren, da über den Du. eine Vielzahl von Einzeluntersuchungen existieren, wie z. B. zur Erörterung der Numeruskategorie im Slavischen im allgemeinen, allgemeine Darstellungen zum Sorbischen mit Beschreibungen der Dualparadigmen, Beschreibungen einzelner Flexionsparadigmen des Ns., deren Besonderheiten und Genese (...). Der Verfasser stellt sich das Ziel, nach einigen einleitenden Bemerkungen zur Übersetzung des NT von Miklawuš Jakubica im 2. Kapitel theoretische Grundlagen zur morphologischen Kategorie zu erörtern, wobei im wesentlichen auf den Numerus im allgemeinen, den Ursprung des Du. und dessen verschiedene Formen, wie natürlicher oder freier, Du. mit zwei und beide und anaphorischer Du. eingegangen wird. Die Untersuchung erfolgt sowohl aus synchroner als auch aus diachroner Sicht, da paradigmatische Vergleiche mit älteren ns. Grammatiken als auch mit der Gegenwartssprache gezogen werden sollen.
    Schlagwort(e): 1548 ; Analyse ; Darstellung ; Dual ; Genese ; Jakubica ; Miklawuš ; Neuen ; niedersorbischen ; Numeruskategorie ; paradigmatische Vergleiche ; Slavische Sprachwissenschaft ; sprachwissenschaftliche ; Studien ; Testament ; Theologie ; Unger ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Sprache: Deutsch
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  • 98
    Publikationsdatum: 2024-04-05
    Beschreibung: The eBook "Building Strategies for Porcine Cancer Models" presents a series of articles demonstrating the state-of-the-art developments in pig models for cancer research. Renowned researchers dedicated to the reproduction, genomic and biological engineering of the pig model for biomedicine contribute to this special research area. Although advances in these areas are occurring at surprising speeds, they are still far from realizing all the potential benefits that this biological model could provide to science. The current biomedical models may limit the frontier of knowledge in the cancer research.
    Schlagwort(e): QH426-470 ; Q1-390 ; Pigs ; Cloning ; Genetic engineering ; Comparative Genomics ; Gene Editing ; Animal Models ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Sprache: Englisch
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  • 99
    Publikationsdatum: 2024-04-05
    Beschreibung: This e-book summarizes recent advances in the young and rapidly developing field of microbial volatiles. Articles included here reveal novel information about the chemical diversity of bacterial and fungal volatiles, their functions, their roles in inter-specific and inter-kingdom interactions and the metabolic and physiological changes their exposure causes in the target organisms. The e-book is divided in three chapters: (1) Natural Functions of Microbial Volatiles; (2) Volatile Production and Ecosystem Functioning and (3) Volatile Detection and Identification.
    Schlagwort(e): QR1-502 ; Q1-390 ; microorganisms ; infochemicals ; natural functions ; induced systemic resistance ; Plants ; antimicrobials ; plant growth promotion ; volatiles ; interactions ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Sprache: Englisch
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  • 100
    Publikationsdatum: 2024-04-05
    Beschreibung: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
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