ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
  • 1
    Online-Ressource
    Online-Ressource
    Notch Signaling in Embryology and Cancer : Molecular Biology of Notch Signaling (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Cytology. ; Embryology. ; Cancer Biology. ; Cell Biology. ; Embryology.
    Beschreibung / Inhaltsverzeichnis: Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling -- Overview of Basic Mechanisms of Notch Signaling in Development and Disease -- Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate -- Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling -- Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster -- Molecular Regulation of Notch Signaling by Gremlin -- Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex -- Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss -- Insulin–dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation -- Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond -- Index.
    Kurzfassung: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
    Materialart: Online-Ressource
    Seiten: XIII, 172 p. 32 illus., 31 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2020.
    ISBN: 9783030364229
    Serie: Advances in Experimental Medicine and Biology, 1227
    URL: https://doi.org/10.1007/978-3-030-36422-9
    DOI: 10.1007/978-3-030-36422-9
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 2
    Online-Ressource
    Online-Ressource
    Medicinal and Aromatic Plants of North America (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Plant physiology. ; Plant Science. ; Agriculture. ; Plant Physiology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction to MAPs in the North America -- Chapter 2. Dr. Duke's Phytochemical and Ethnobotanical databases, a cornerstone in the validation of ethnoveterinary medicinal plants, as demonstrated by data on pets in British Columbia -- Chapter 3. Pharmacopoeial Wild Medicinal Plants of North America -- Chapter 4. Medicinal Plant Products, a Discussion of Actual or Probable versus Perceived Sources -- Chapter 5. Juniper species in North America to the same species in Europe with respect to phytochemistry and bioactivity -- Chapter 6. Mentha Genetic Diversity at the US National Clonal Germplasm Repository in Corvallis, Oregon -- Chapter 7. Advances in the research of basil -- Chapter 8. Advances in ther research of catnip -- Chapter 9. Diversity, conservation and sustainable harvest of medicinal plants in North America -- Chapter 10. The Great botanist, Jim Duke -- Chapter 11. TBC -- Chapter 12. Taxol or the story of the American yew -- Chapter 13. The Indian Tobacco -- Chapter 14. The American Elderberry -- Chapter 15. The American Ginseng.
    Kurzfassung: This volume is aimed at offering an insight into the present knowledge of the vast domain of Medicinal and Aromatic Plants with a focus on North America. In this era of global climate change the volume is meant to provide an important contribution to a better understanding of the diverse world of Medicinal and Aromatic Plant research, production and utilization.
    Materialart: Online-Ressource
    Seiten: VIII, 342 p. 59 illus., 24 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030449308
    Serie: Medicinal and Aromatic Plants of the World, 6
    URL: https://doi.org/10.1007/978-3-030-44930-8
    DOI: 10.1007/978-3-030-44930-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 3
    Online-Ressource
    Online-Ressource
    Tumor Microenvironment : Molecular Players – Part B (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Cytology. ; Internal medicine. ; Cancer Microenvironment. ; Cancer Biology. ; Cell Biology. ; Internal Medicine.
    Beschreibung / Inhaltsverzeichnis: MicroRNAs in the tumor microenvironment -- The Impact of Estrogen in the Tumor Microenvironment -- The non-bone related role of RANK/RANKL signaling in cancer -- Modulation of Cancer Cell Growth and Progression by Caveolin-1 in the Tumor Microenvironment -- Exosomes: Novel Players of Therapy Resistance in Neuroblastoma -- COX-2 Signaling in the Tumor Microenvironment -- Renin–angiotensin system in the tumor microenvironment -- Stem cell secreted factors in the tumor microenvironment -- Tight interplay between therapeutic monoclonal antibodies and the tumor microenvironment in cancer therapy -- Tumor Microenvironment & Nitric Oxide: Concepts and Mechanisms -- Index.
    Kurzfassung: This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including MicroRNAs, estrogen, Caveolin-1, Nitric Oxide, RANK/RANKL signaling, , COX-2 Signaling, Renin–angiotensin system, and more. Taken alongside its companion volumes, Tumor Microenvironment: Molecular Players – Part B updates us on what we know about the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Materialart: Online-Ressource
    Seiten: XIV, 162 p. 22 illus., 21 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030502249
    Serie: Advances in Experimental Medicine and Biology, 1277
    URL: https://doi.org/10.1007/978-3-030-50224-9
    DOI: 10.1007/978-3-030-50224-9
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 4
    Online-Ressource
    Online-Ressource
    A Monograph of Paris (Melanthiaceae) : Morphology, Biology, Systematics and Taxonomy (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Plant genetics. ; Plant ecology. ; Plant Science. ; Plant Genetics. ; Plant Ecology.
    Beschreibung / Inhaltsverzeichnis: Preface -- Acknowledgement -- Chapter 1. Taxonomic History -- Chapter 2. Morphology -- Chapter 3. Biology -- Chapter 4. Economic Importance -- Chapter 5. Phylogeny, classification, and biogeography -- Chapter 6. Taxonomic revision -- Chapter 7. Conservation status.
    Kurzfassung: This book provides essential information on the morphology, biology, phytochemistry, pharmaceutical prospects, evolution, phylogeny, biogeography, and taxonomy of Paris (Melanthiaceae), a morphologically distinctive plant genus with great economic importance. Since the establishment of this genus, 70 species and 24 subspecific taxa have been described, resulting in considerable confusion in species delimitation. In this book, the taxonomy of all described taxa is carefully revised. Based on multi-disciplinary evidences, a revised classification system of Paris containing five sections is outlined. Every species is provided with a concise but diagnostic description, a color illustration, photographs that highlight distinguishing characters, examined specimens and distribution range. The interspecific relationships are clarified with an identification key. This monograph offers taxonomists, evolutionary biologists, ecologists, horticulturalists, phytochemists, and practitioners a thorough and up-to-date overview about this interesting plant group. It is equally valuable for undergraduate and graduate students, teachers and professionals engaged in related fields.
    Materialart: Online-Ressource
    Seiten: XIII, 203 p. 134 illus., 110 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811579035
    URL: https://doi.org/10.1007/978-981-15-7903-5
    DOI: 10.1007/978-981-15-7903-5
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 5
    Online-Ressource
    Online-Ressource
    Immunotherapy for Gastrointestinal Malignancies (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Biochemical markers. ; Immunotherapy. ; Cancers. ; Biomarkers. ; Immunotherapy.
    Beschreibung / Inhaltsverzeichnis: 1 Tumor heterogeneity: challenges and perspectives for gastrointestinal cancer therapy -- 2 immune composition of gastrointestinal tract of Gut -- 3 Immunomarkers for detection of GI malignancies -- 4 Immuno-therapeutics of gastrointestinal malignancies -- 5 Immune cell therapy against gastrointestinal tract cancers -- 6 Immune checkpoint inhibitors in gastrointestinal malignancies -- 7 Monoclonal Antibody therapy against gastrointestinal tract cancers -- 8 Therapeutic Vaccines for Gastrointestinal Malignancies -- 9 Immuno-Oncology of Oesophageal Cancer -- 10 Association between IL6 gene polymorphisms and gastric cancer risk: A meta-analysis of case-control studies -- 11 Immuno-oncology of colorectal cancer -- 12 Immune targets in colorectal cancer -- 13 Applications of computational biology in gastrointestinal malignancies. .
    Kurzfassung: This book reviews current immunotherapeutic strategies for gastrointestinal (GI) malignancies, including immune composition, immune checkpoint inhibitors, cell therapy, and peptide vaccines used to protect against esophageal, gastric, hepato-biliary, pancreatic and colorectal cancers. It also discusses the current challenges of using immunotherapy for the treatment of gastrointestinal malignancies. The book reviews highly sensitive and specific immunomarkers for the detection of GI malignancies, and examines therapeutic vaccines and the major cytokines involved in GI immunotherapy, as well as their basic biology and clinical applications. In closing, the book explores various aspects of computational biology for the detection and treatment of GI malignancies. .
    Materialart: Online-Ressource
    Seiten: XII, 251 p. 34 illus., 27 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811564871
    Serie: Diagnostics and Therapeutic Advances in GI Malignancies,
    URL: https://doi.org/10.1007/978-981-15-6487-1
    DOI: 10.1007/978-981-15-6487-1
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 6
    Online-Ressource
    Online-Ressource
    Lipid Metabolism in Tumor Immunity (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Bioinformatics. ; Immunology. ; Cancer Biology. ; Computational and Systems Biology. ; Immunology.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction: Introduction of lipids, lipid metabolism and tumor immunity -- 2. ipid metabolism and lipidomics -- 3. Applications of lipidomics in tumour immunity.-4. Overview: Lipid metabolism in tumour microenvironment -- 5. Lipid metabolism in cancer cells -- 6. Lipid metabolism in tumour-associated NK -- 7. Lipid metabolism in tumour-associated macrophages -- 8. Lipid metabolism in tumour-associated MDSCs -- 9. Lipid metabolism in tumour-associated fibroblasts -- 10. Lipid metabolism in tumour-associated B cells -- 11. Lipid metabolism in tumour-infiltrating T cells -- 12. Lipid metabolism and angiogenesis -- 13. Lipid metabolism and tumor antigen-presenting -- 14. Lipid metabolism and immune checkpoints.
    Kurzfassung: This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery. .
    Materialart: Online-Ressource
    Seiten: XI, 211 p. 24 illus., 23 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789813367852
    Serie: Advances in Experimental Medicine and Biology, 1316
    URL: https://doi.org/10.1007/978-981-33-6785-2
    DOI: 10.1007/978-981-33-6785-2
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 7
    Online-Ressource
    Online-Ressource
    Auxins, Cytokinins and Gibberellins Signaling in Plants (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Botanical chemistry. ; Plant physiology. ; Agriculture. ; Plant Science. ; Plant Biochemistry. ; Plant Physiology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: How the three organ-produced signals: auxin, cytokinin and gibberellin, induce and regulate wood formation and adaptation -- Role of plant growth regulators in the plant-environment interaction and epigenetic regulation of auxin -- The role of auxin and cytokinin signaling components in de novo shoot organogenesis -- Mechanism of crosstalk between cytokinin and gibberellin -- In vitro responses of some Mediterranean fruit crops to auxin, cytokinin and gibberellin treatments -- Integrative approach of the root architecture by interaction between auxin and nutrients -- Insights into Biosynthesis and Signaling of Cytokinins during Plant Growth, Development and Stress Tolerance -- Cytokinin signaling in plants under salt stress -- Auxin and Cytokinin Signaling in Plant Stress Response -- Gibberellins' cross talk and signal transduction in plant stress response -- Crosstalk between Salicylic acid and Auxins, Cytokinins and Gibberellins under biotic stress -- Understanding the crosstalk between chromatin remodeling mechanism and phytohormones signaling for maintenance of plant developmental plasticity: an insight -- Phytohormone-mediated regulation of sprouting in tuber and storage root crops -- Role of phytohormones in plant-microbial interaction -- Iron toxicity tolerance in rice: roles of auxins and gibberellins -- New auxin and cytokinin related compounds based on synthetic low molecular weight heterocycles.
    Kurzfassung: Plant hormones have pivotal roles in the regulation of plant growth, development, and reproduction. Their signaling pathways are interconnected in a complex network, which provides plants with an enormous regulatory potential to rapidly adapt to their environment and to utilize their limited resources for growth and survival in a cost-efficient manner. Auxin is a hormone molecule whose activity levels are most important for its regulatory roles during plant cell, organ, and tissue development. Therefore, the precise regulation of auxin levels is an essential mechanism to fine-tune the activity of this powerful hormone during plant growth and development. Likewise, cytokinins exhibit a wide range of physiological functions, including regulation of shoot and root apical meristems, stimulation of branching, vascular development, chloroplast differentiation, stabilization of the structure and function of the photosynthetic machinery, delay of senescence, stomata opening, and elevation of the sink strength and nutritional signaling. Moreover, gibberellins also regulate many aspects of plant growth and development including seed germination, stem elongation, leaf expansion, and flower and fruit development. The broad implication of gibberellins in plant development is strictly associated with tight regulation of their metabolism by multiple environmental and endogenous factors, ranging from light and temperature to other hormones including feedback control. Understanding the significant roles of these phytohormones in plant biology, the current subject has attracted the attention of scientists from across the globe. This comprehensive volume “Auxins, Cytokinins and Gibberellins Signaling in Plants” highlights the various prospects involved in the current scenario. The book comprises the chapters from diverse areas dealing with biotechnology, molecular biology, proteomics, genomics, metabolomics, etc.
    Materialart: Online-Ressource
    Seiten: IX, 377 p. 63 illus., 39 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031054273
    Serie: Signaling and Communication in Plants,
    URL: https://doi.org/10.1007/978-3-031-05427-3
    DOI: 10.1007/978-3-031-05427-3
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 8
    Online-Ressource
    Online-Ressource
    Plant Molecular Farming : Applications and New Directions (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Plant biotechnology. ; Pharmaceutical chemistry. ; Agriculture. ; Proteins . ; Plant Science. ; Plant Biotechnology. ; Pharmaceutics. ; Agriculture. ; Protein Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Chapter. 1. Molecular Farming in Plants: Introduction and Applications -- Chapter. 2. Tools and Techniques Used in Plant Molecular Farming -- Chapter. 3. Production of plant natural products in heterologous microbial species -- Chapter. 4. Sustainable Manufacturing of Vaccines, Antibodies, and other Pharmaceuticals -- Chapter. 5. Limitations, Biosafety, ethics, regulatory issues in molecular farming in plants -- Chapter. 6. Conclusion and Perspectives.
    Kurzfassung: Molecular farming is a biotechnological approach that includes the genetic adjustment of agricultural products to create proteins and chemicals for profitable and pharmaceutical purposes. Plant molecular farming describes the manufacture of recombinant proteins and other biologically active product in plants. This approach depends on a genetic transformation of plants that can be accomplished by the methods of stable gene transfer, such as gene transfer to nuclei and chloroplasts, and unstable transfer methods like viral vectors. The requirement for recombinant proteins in terms of quality, quantity, and diversity is increasing exponentially This demand is traditionally met by recombinant protein construction technologies and the engineering of orthodox expression systems based on bacteria or mammalian cell cultures. However, majority of developing countries cannot afford the high costs of medicine derived from such existing methods. Hence, we need to produce not only the new drugs but also the cheaper versions of those already present in the market. Plant molecular farming is considered as a cost-effective technology that has grown and advanced tremendously over the past two decades. This book summarizes the advances and challenges of plant molecular farming for all those who are working on or have an interest in this rapidly emerging area of research.
    Materialart: Online-Ressource
    Seiten: IX, 77 p. 10 illus., 9 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031127946
    Serie: SpringerBriefs in Plant Science,
    URL: https://doi.org/10.1007/978-3-031-12794-6
    DOI: 10.1007/978-3-031-12794-6
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 9
    Online-Ressource
    Online-Ressource
    Progress in Botany Vol. 81 (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Forestry. ; Botanical chemistry. ; Biotic communities. ; Plant genetics. ; Plant physiology. ; Plant Science. ; Forestry. ; Plant Biochemistry. ; Ecosystems. ; Plant Genetics. ; Plant Physiology.
    Beschreibung / Inhaltsverzeichnis: 1. Nitrogen and Sulfur Metabolism in Microalgae and Plants: 50 Years of Research -- 2. Progress Toward Deep Sequencing-Based Discovery of Stress-Related MicroRNA in Plants and Available Bioinformatics Tools -- 3. Recent Advances in MS-Based Plant Proteomics: Proteomics Data Validation Through Integration with Other Classic and -Omics Approaches -- 4. Membrane Trafficking and Plant Signaling -- 5. Molecular Aspects of Iron Nutrition in Plants -- 6. Urea in Plants: Metabolic Aspects and Ecological Implications -- 7. Biosynthesis and Regulation of Secondary Cell Wall -- 8. Stress-Induced Microspore Embryogenesis in Crop Plants: Cell Totipotency Acquisition and Embryo Development -- 9. Potential of Microalgae Biomass for the Sustainable Production of Bio-commodities -- 10. Crassulacean Acid Metabolism and Its Role in Plant Acclimatization to Abiotic Stresses and Defence Against Pathogens -- 11. The Role of the Shikimate and the Phenylpropanoid Pathways in Root-Knot Nematode Infection -- 12. Functional Diversity of Photosynthesis, Plant-Species Diversity, and Habitat Diversity -- 13. When the Tree Let Us See the Forest: Systems Biology and Natural Variation Studies in Forest Species -- 14. The Ecological Importance of Winter in Temperate, Boreal, and Arctic Ecosystems in Times of Climate.
    Kurzfassung: With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on plant physiology, biochemistry, genetics and genomics, forests, and ecosystems.
    Materialart: Online-Ressource
    Seiten: XIII, 399 p. 47 illus., 38 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030363277
    Serie: Progress in Botany, 81
    URL: https://doi.org/10.1007/978-3-030-36327-7
    DOI: 10.1007/978-3-030-36327-7
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 10
    Online-Ressource
    Online-Ressource
    Autophagy in tumor and tumor microenvironment (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Immunology. ; Medical microbiology. ; Molecular genetics. ; Stem cells. ; Cell death. ; Cancer Biology. ; Immunology. ; Medical Microbiology. ; Molecular Genetics. ; Stem Cell Biology. ; Cell Death.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Role of xenobiotic in autophagy inflection in cell death and carcinogenesis -- Chapter 2. Autophagy – An agonist and antagonist with an interlink of apoptosis in cancer -- Chapter 3. Cross-talk between DNA damage and autophagy and its implication in cancer therapy -- Chapter 4. miRNAs and its regulatory role on autophagy in tumor microenvironment -- Chapter 5. Exploring the metabolic implications of autophagy modulation in tumor microenvironment -- Chapter 6. Mitophagy and Reverse Warburg Effect: Metabolic Compartmentalization of Tumor Microenvironment -- Chapter 7. Mitochondrial Biogenesis, Mitophagy, and Mitophagic cell death in Cancer Regulation: A Comprehensive Review -- Chapter 8. Mechanical stress-induced autophagy: a key player in cancer metastasis -- Chapter 9. The Interplay of Autophagy and the Immune system in the Tumor Microenvironment -- Chapter 10. Relevance of autophagy in cancer stem cell and therapeutic -- Chapter 11. The Autophagy Conundrum in Cancer Development, Progression and Therapeutics -- Chapter 12. Targeting Autophagy in Cancer: Therapeutic implications -- Chapter 13. Mechanistic insights into Autophagosome-Lysosome Fusion in Cancer Therapeutics.
    Kurzfassung: This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.
    Materialart: Online-Ressource
    Seiten: VII, 280 p. 38 illus., 37 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811569302
    URL: https://doi.org/10.1007/978-981-15-6930-2
    DOI: 10.1007/978-981-15-6930-2
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 11
    Online-Ressource
    Online-Ressource
    Tumor Microenvironment : Signaling Pathways – Part B (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Biophysics. ; Cell interaction. ; Cytology. ; Cancer Microenvironment. ; Mechanobiological Cell Signaling. ; Cell Biology. ; Cancer Biology.
    Beschreibung / Inhaltsverzeichnis: Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index.
    Kurzfassung: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Materialart: Online-Ressource
    Seiten: XIII, 191 p. 31 illus., 25 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030471897
    Serie: Advances in Experimental Medicine and Biology, 1270
    URL: https://doi.org/10.1007/978-3-030-47189-7
    DOI: 10.1007/978-3-030-47189-7
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 12
    Online-Ressource
    Online-Ressource
    The Systemic Effects of Advanced Cancer : A Textbook on Cancer-Associated Cachexia (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Oncology. ; Immunology. ; Metastasis. ; Cytology. ; Cancer Biology. ; Oncology. ; Immunology. ; Metastasis. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. A Systemic View of Metastatic Disease: Inter-organ Crosstalk and Therapeutic Implications -- Part I. Systemic Regulation in Metastatic Disease -- Chapter 2. Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles -- Chapter 3. Bone Metastasis: Systemic Regulation and Impact on Host -- Chapter 4. Targeting Metastatic Disease: Challenges and New Opportunities -- Part II. Cachexia: A Debilitating Systemic Effect of Cancer -- Chapter 5. Signaling Pathways That Promote Muscle Catabolism in Cachexia -- Chapter 6. The Role of Interleukin-6 Cytokines in Cancer Cachexia -- Chapter 7. NF-kB Signaling in the Macroenvironment of Cancer Cachexia -- Part III. Therapy-induced Muscle Wasting -- Chapter 8. Therapy-induced Toxicities Associated with the Onset of Cachexia -- Chapter 9. Bone-muscle Crosstalk in Advanced Cancer and Chemotherapy -- Part IV. Preventing and Targeting Cachexia in Cancer -- Chapter 10. New Developments in Targeting Cancer Cachexia -- Chapter 11. Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer.
    Kurzfassung: This textbook discusses the systemic consequences of cancer, covering a range of topics from tumor-promoting systemic effects to the development of cachexia, as summarized in the introductory chapter 1. Part I of this textbook focuses on tumor-promoting systemic effects and begins with a chapter on how tumor-derived extracellular vesicles and particles lay the foundation for future metastases (Chapter 2). Chapter 3 discusses how metastatic cells that have colonized the bone impact the local bone microenvironment, neighboring muscles, and host physiology. Chapter 4 summarizes the available strategies for targeting metastatic cancer and emphasizes the need to incorporate a systemic view of the disease. Following this overview of the systemic effects of cancer progression, Part II of the textbook discusses cancer-induced cachexia, a debilitating systemic effect of advanced cancer. Chapters 5-7 examine the key signaling pathways (interleukin-6/GP130, NF-kB, and muscle proteolysis) that drive the development of cancer cachexia. Chapters 8 and 9 in Part III of this textbook explore how toxicities from anti-cancer therapy are associated with the onset of cachexia in cancer patients, and provide insight into potential approaches to simultaneously target both cancer and cachexia. Chapters 10 and 11 (Part IV) conclude this textbook by outlining promising approaches for the diagnosis and treatment of cachexia as well as strategies to prevent the development of cachexia through exercise. An understanding of the systemic effects of cancer is essential for the design of effective anti-cancer and anti-cachexia treatment strategies. As such, this textbook provides key information for both students and scientists engaged in cancer research and oncology.
    Materialart: Online-Ressource
    Seiten: VI, 203 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031095184
    URL: https://doi.org/10.1007/978-3-031-09518-4
    DOI: 10.1007/978-3-031-09518-4
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 13
    Online-Ressource
    Online-Ressource
    Cancer Biology: How Science Works (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Genetics. ; Molecular biology. ; Cancer Biology. ; Genetics and Genomics. ; Molecular Biology.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction to cancer -- 2. Oncogenes, signal transduction and the hallmarks of cancer -- 3. Tumor suppressor genes and cell fate control -- 4. Multi-step tumorigenesis and genome instability -- 5. Cancer genomics -- 6. Cancer epigenomics -- 7. Aging and cancer -- 8. Tumor microenvironment -- 9. Metastasis and cachexia -- 10. Cancer immunity -- 11. Architecture of cancer therapies.
    Kurzfassung: Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
    Materialart: Online-Ressource
    Seiten: XVII, 167 p. 72 illus., 71 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030756994
    URL: https://doi.org/10.1007/978-3-030-75699-4
    DOI: 10.1007/978-3-030-75699-4
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 14
    Online-Ressource
    Online-Ressource
    Obesity and Cancer (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Diseases. ; Immunology. ; Bioinformatics. ; Cancer Biology. ; Diseases. ; Immunology. ; Bioinformatics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Obesity induced chronic low-level inflammation and cancers -- Chapter 2. Adipose tissue produced estrogen as risk factor for cancers -- Chapter 3. Insulin and Insulin-like growth factor-1 associated cancers.-Chapter 4. Adipokines play important role in cell proliferation and antiproliferation -- Chapter 5. mTOR and AMP-activated protein kinase in obesity and cancer -- Chapter 6. Immune response and oxidative stress in obesity induced cancer -- Chapter 7. Role of gene polymorphism in obesity and cancer -- Chapter 8. Therapeutic role of green tea in obesity and cancer -- Chapter 9. Effect of dietary phytochemicals in obesity and cancer -- Chapter 10. Resveratrol as anti-obesity and anticancer agent -- Chapter 11. EGCG as anti-obesity and anticancer agent -- Chapter 12. miRNAs as therapeutic target in obesity and cancer -- Chapter 13. In silico updates on lead identification for obesity and cancer -- Chapter 14. In vivo models for obesity and obesity related carcinogenesis -- Chapter 15. Estrogen signaling based current and potential therapies against obesity and related diseases -- Chapter 16. Autophagy at the crossroad of obesity mediated cancer progression.
    Kurzfassung: This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry. .
    Materialart: Online-Ressource
    Seiten: IX, 361 p. 38 illus., 23 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811618468
    URL: https://doi.org/10.1007/978-981-16-1846-8
    DOI: 10.1007/978-981-16-1846-8
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 15
    Online-Ressource
    Online-Ressource
    A Field Guide to Tropical Plant Families (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Plant anatomy. ; Biodiversity. ; Plant Science. ; Plant Anatomy and Morphology. ; Biodiversity.
    Beschreibung / Inhaltsverzeichnis: Part I – User manual and architectural concepts. Chapter 1. Introduction -- Chapter 2. How to use this book 6 -- Chapter 3. Architectural concepts and key to the models -- Part II. Identification keys -- Chapter 4. Key to the groups of families of trees and shrubs (groups 1 to 52) -- Chapter 5. Keys to families of trees and shrubs -- Chapter 6. Supplementary keys -- Chapter 7. Keys to the groups of families of lianas and woody epiphytic (groups 53 to 57) -- Chapter 8. Keys to families of lianas and woody epiphytes -- PART III. Description of the families -- Chapter 9. Acanthaceae to Asteraceae -- Chapter 10. Bignoniaceae to Buxaceae -- Chapter 11. Cactaceae to Cycadaceae -- Chapter 12. Dichapetalaceae to Dipterocarpaceae -- Chapter 13. Ebenaceae to Euphorbiaceae -- Chapter 14. Fagaceae -- Chapter 15. Gentianaceae to Goupiaceae -- Chapter 16. Hamamelidaceae to Humiriaceae -- Chapter 17. Icacinaceae s.l. to Irvingiaceae -- Chapter 18. Juglandaceae -- Chapter 19. Lamiaceae to Lythraceae -- Chapter 20. Magnoliaceae to Myrtaceae -- Chapter 21. Nyctaginaceae,- Chapter 22. Ochnaceae to Oxalidaceae -- Chapter 23. Pandaceae to Putranjivaceae -- Chapter 24. Rhabdodendraceae to Rutaceae -- Chapter 25. Sabiaceae to Symplocaceae -- Chapter 26. Tetramelaceae to Torricelliaceae -- Chapter 27. Ulmaceae s.l. to Urticaceae -- Chapter 28. Verbenaceae to Vochysiaceae -- Chapter 29. Zygophyllaceae s.l -- Chapter 30. Herbaceous versus arborescent habit in the families and orders of flowering plants - evolutionary trends.
    Kurzfassung: This book provides an identification system permitting recognition of plant families in all seasons by means of morphological and macroanatomical features which are easily observable, such as bark, exudates, stems and leaves characters. Studies of forest vegetation may differ in their underlying objectives, but they all require taxonomic knowledge. The process of taxonomy begins with an inventory of the flora, which has been based to a large extent on reproduction-related organs, such as flowers and fruits. But, those are often difficult to observe and may not exist in the field at a given time. Unlike most such guides or keys, this book can be used anywhere in the tropics and provides, in a straightforward two or three-step process, identification to the level of families, which are now circumscribed according to molecular as well as morphological characters in the universally accepted scheme of the Angiosperm Phylogeny Group. Plant architecture is not a prerequisite theme for plant identification; however, we think that an introduction to this subject is not out of place in this book (architectural traits are taxonomically sound): it is now time for botanists working in the tropics to have an idea on how the whole organism keeps growing. Within the family accounts, there is information concerning important economic plants with notes on the larger genera and, particularly helpfully, discussion of families readily confused and how to separate them. Descriptions of the families rely on short diagnosis bolstered by many photographic pictures, lines drawings and extracts from the author’s field books, all showing features of plants as they are found in the forest.
    Materialart: Online-Ressource
    Seiten: XVII, 494 p. 909 illus., 850 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031059421
    URL: https://doi.org/10.1007/978-3-031-05942-1
    DOI: 10.1007/978-3-031-05942-1
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 16
    Online-Ressource
    Online-Ressource
    Tumor Microenvironment : Extracellular Matrix Components – Part A (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Stem cells. ; Regenerative medicine. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering.
    Beschreibung / Inhaltsverzeichnis: The tumor microenvironment: focus on extracellular matrix -- Keratan Sulphate in the Tumour Environment -- Hyaluronan in the tumor microenvironment -- Fibronectin in the tumor microenvironment -- Matrix metalloproteinases role in tumor microenvironment -- Flipping the Molecular Switch: Influence of Perlecan and its Modifiers in the Tumor Microenvironment -- Heparan sulfate in the tumor microenvironment -- The role of Glypican-1 in the tumour microenvironment -- Index.
    Kurzfassung: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components with the tumor during cancer development. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include heparan sulphate, hyaluronan, fibronectin, perlecan, glypican, matrix metalloproteinases, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part A updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newer generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book will be an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapter authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.
    Materialart: Online-Ressource
    Seiten: XI, 181 p. 29 illus., 24 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030401467
    Serie: Advances in Experimental Medicine and Biology, 1245
    URL: https://doi.org/10.1007/978-3-030-40146-7
    DOI: 10.1007/978-3-030-40146-7
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 17
    Online-Ressource
    Online-Ressource
    Biotechnological Advances in Bamboo : The “Green Gold” on the Earth (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Plant biotechnology. ; Plant cells and tissues. ; Plant Science. ; Plant Biotechnology. ; Plant Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Bamboo: origin, habitat, distributions and global prospective -- Molecular markers in bamboos: understanding reproductive biology, genetic structure, interspecies diversity and clonal fidelity for conservation and breeding -- Standard protocols for in vitro propagation of bamboo with emphasis on axillary shoot proliferation -- Somatic embryogenesis in bamboos: advances and prospects -- Initiation and establishment of cell suspension culture in bamboo -- Micro-morpho-anatomical alterations in micropropagated plants of endrocalamus strictus -- Micropropagation of bamboos and clonal fidelity assessment using molecular markers -- Standardization of laboratory to land transfer strategies of micropropagated plantlets of bamboo -- Management of bamboo genetic resources and clonal production systems -- Polymorphism and phylogenetic relationships in bamboo -- Transgenics approaches in Bamboo -- Advances in Conservation of Bamboo Genetic Resources through Whole Seeds Cryopreservation -- Application of Biotechnological Tool in Bamboo Improvement -- Ethnobamboology: traditional uses of bamboos and opportunities to exploit genomic resources for better exploitation -- Bamboo flowering in South America: what the past tells about the future -- Molecular Markers in Bamboo Genotyping: Prospects for Conservation and Breeding -- Application of bamboo in the food and pharmaceutical industry -- Functional pasta: a comparative study of the use of bamboo shoot fiber and white fibers -- Bamboo fiber as a substitute for fat and/or sugar in cookies -- Practical application of bamboo as a building material: trends and challenges.
    Kurzfassung: “Green gold” or “Poor Man’s Timber” are commonly used terms for bamboo that is a valuable and renewable resource of the world, and has always been an elemental part of human beings in terms of social and economic value. Bamboo is considered a multipurpose plant and has a prolonged history as an adaptable and extensively used renewable resource in conventional and commercial applications. Therefore, the annual demands for bamboos have already out-crossed the annual yields across the world. And the current scenario has forced scientists to pay more attention to the utilization of biotechnological tools for better understanding and improving bamboos. The book provides an overview of the different biotechnological approaches to advance bamboo research and better utilization of bamboo resources for human beings. Various applications of biological techniques in relation to bamboo have been discussed in details, for example, plant tissue culture techniques, somatic embryogenesis, germplasm conservation techniques, use of the molecular markers, transcriptomics, polymorphism, and phylogenetic relations in bamboo. It also addresses the novel industrial applications of bamboo in structural, food, and pharmaceuticals along with traditional uses. The aggregated information in this book demonstrates the way for the improved and sustainable practice of bamboos to fulfill the future needs of the world. This book is intended for use in both the industry and academia.
    Materialart: Online-Ressource
    Seiten: XV, 481 p. 82 illus., 72 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811613104
    URL: https://doi.org/10.1007/978-981-16-1310-4
    DOI: 10.1007/978-981-16-1310-4
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 18
    Online-Ressource
    Online-Ressource
    Plant Metal and Metalloid Transporters (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Plant molecular biology. ; Botanical chemistry. ; Plant Science. ; Agriculture. ; Plant Molecular Biology. ; Plant Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Plant Metal and Metalloid Transport -- Chapter 2. Heavy Metals: Transport in Plants and their Physiological and Toxicological Effects -- Chapter 3. The Role of ABC Transporter in Metal Tranasport in Plants -- Chapter 4. Cadmium, A Non-Essential Heavy Metal: Uptake, Translocation, Signaling, Detoxification, and Impact on Amino Acid Metabolism -- Chapter 5. Natural Resistance Associated Macrophage Proteins (NRAMP): Functional Significant of Metal Transport in Plants -- Chapter 6. Role of Heavy Metal Atpases in Transport of Cadmium and Zinc in Plants -- Chapter 7. The Versatile Role of Plant Aquaglyceroporins in Metalloid Transport -- Chapter 8. The Multidrug and Toxic Compound Extrusion (MATE) Family in Plants and Their Significance in Metal Transport -- Chapter 9. Molecular Mechanism of Aluminium Tolerance in Plants: An Overview -- Chapter 10. Functional, Structural, and Transport Aspects of ZIP in Plant -- Chapter 11. The Function of HAK as K+ Transporter and AKT as Inward Rectifying Agent in The K+ Channel -- Chapter 12. The Mechanism of Silicon Transport in Plants -- Chapter 13. The Copper Transport Mechanism in Plants -- Chapter 14. Plant Metal Tolerance Proteins: Insight Into their Roles in Metal Transport and Homeostasis for Future Biotechnological Applications -- Chapter 15. Co-Transport Mechanism in Plants for Metals and Metalloids -- Chapter 16. Metal Nanoparticles Implication, Transport, and Detection in Plants -- Chapter 17. Transcription Factors and Metal Stress Signalling in Plants -- Chapter 18. Heavy Metal Transporters, Phytoremediation Potential and Biofortification -- Chapter 19. Phytoremediation and Biofortification: Contrasting Yet Similar Approaches of Manipulating Plant Metal(Loid) Homeostasis for Societal Benefit.
    Kurzfassung: This edited book stands as a one place knowledge hub for plant metal(loid) transporters. The book comprehensively covers holistic aspect of metal(loid) transporters involved in uptake and translocation of essential as well as toxic metal(loid)s. Essential and beneficial metal(loid)s are required in every biological process for normal plant growth and development, however in excess they are toxic. There are toxic metal(loid)s also whose accumulation in plants interferes with normal cellular functioning and hampers growth of plants. Hence, metal(loid) uptake and accumulation in plants is a highly regulated phenomenon involving the role of several transporters, enzymes, metabolites, transcription factors and post translational modifications. The book contains chapters from the experts and the contents of the book are presented in simple language and represented through beautiful and scientifically informative figures and tables. This book is of interest to teachers, researchers, doctoral and graduate students working in the area of plant physiology, environmental biotechnology, plant biotechnology metal(loid) stress, phytoremediation and crop biofortification.
    Materialart: Online-Ressource
    Seiten: XIII, 454 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811961038
    URL: https://doi.org/10.1007/978-981-19-6103-8
    DOI: 10.1007/978-981-19-6103-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 19
    Online-Ressource
    Online-Ressource
    Current Advances in the Science of Osteosarcoma : Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Medical microbiology. ; Cytology. ; Pediatrics. ; Cancer Biology. ; Medical Microbiology. ; Cell Biology. ; Pediatrics.
    Beschreibung / Inhaltsverzeichnis: The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies -- Genomics and the Immune Landscape of Osteosarcoma -- RECQ DNA Helicases and Osteosarcoma -- Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma -- Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma -- Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response -- Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma -- Wnt Signaling in Osteosarcoma -- Receptor Tyrosine Kinases in Osteosarcoma: 2019 update -- The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets -- Autophagy in OS -- Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs -- Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment -- Comparative Immunology and Immunotherapy of Canine Osteosarcoma -- Index.
    Kurzfassung: This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.
    Materialart: Online-Ressource
    Seiten: XIII, 233 p. 34 illus., 23 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2020.
    ISBN: 9783030430856
    Serie: Advances in Experimental Medicine and Biology, 1258
    URL: https://doi.org/10.1007/978-3-030-43085-6
    DOI: 10.1007/978-3-030-43085-6
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 20
    Online-Ressource
    Online-Ressource
    The Geography of Black Pepper (Piper nigrum) : The "King" of Spices – Volume 1 (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Food science. ; Plant ecology. ; Economic geography. ; Agriculture. ; Plant Science. ; Food Science. ; Plant Ecology. ; Economic Geography. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Preface -- Chapter 1 Introduction -- Chapter 2 The Pepper Plant—Its Botany and Chemistry -- Chapter 3 Pepper Agronomy -- Chapter 4 The Role of the Nutrient Buffer Power Concept in Pepper Nutrition -- Chapter 5 Establishing a Pepper Plantation -- Chapter 6 Pepper Pests and Their Control -- Chapter 7 The Processing of Black Pepper on Farm -- Chapter 8 An Account of Indonesian Pepper Processing -- Chapter 9 Industrial Processing of Black Pepper -- Chapter 10 The Future of the Global Pepper Economy -- Chapter 11 Pepper Economy in India -- Chapter 12 Pepper Pharmacopoeia -- Chapter 13 Consumer Products Out of Black Pepper -- Chapter 14 Value Addition in Pepper -- Chapter 15 Conclusions and a Peep Into Pepper’s Future -- PRECISE QUANTIFICATION OF PLANT NUTRIENT BIO AVAILABILITY FOR BLACK PEPPER AND CARDAMOM -- TECHNOLOGICAL INNOVATIONS IN SPICES RESEARCH AND DEVELOPMENT!!!.
    Kurzfassung: This book considers all aspects of black pepper from its growth, as a flowering vine, to how the dried fruit (peppercorn) is used as a spice and traded as a commodity. It is the economic mainstay of several India states and, principally, in Kerala State, with the Indian subcontinent being the largest black pepper producer. Indonesia has also emerged as a large producer of black pepper. Black pepper commands a leading position among the spices and has an immense commercial importance to world trade, finding its way onto the dining table of millions around the world, on the European and North American continents, and Japan. The use of black pepper ranges from a simple dietary component and flavour enhancer, to that of a spice with huge pharmacological benefits. .
    Materialart: Online-Ressource
    Seiten: XIV, 162 p. 24 illus., 19 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030528652
    URL: https://doi.org/10.1007/978-3-030-52865-2
    DOI: 10.1007/978-3-030-52865-2
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 21
    Online-Ressource
    Online-Ressource
    Wetland Plants : A Source of Nutrition and Ethno-medicines (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Nutrition   . ; Medicinal chemistry. ; Food science. ; Plant Science. ; Nutrition. ; Medicinal Chemistry. ; Food Science.
    Beschreibung / Inhaltsverzeichnis: Foreword -- Preface -- Wetlands and Wetland Plants -- Climate of Wetlands -- Types of Wetlands and Wetland Plants -- Importance of Biodiversity in Wetlands -- Nutritive Value of Wetland Flora -- Medicinally Important Wetland Flora -- Threats to Biodiversity of Wetlands -- Conservation Strategies of Wetland Flora -- Wetland Plants of Himalayas: A case study -- A Pictorial Guide to Wetland plants of Himalayas -- Bibliography.
    Kurzfassung: Due to their high nutritive value and the presence of secondary metabolites, wetland plants can be consumed by humans as food and utilized as medicinal drugs. Significant numbers of ethno-botanic resources have been reported to extract useful compounds, which can be used as pharmaceuticals. Wetland plants are also very valuable as an energy source, as fuel for fish smoking and for domestic energy. These plants can be harvested as wild stock, or cultivated in flooded paddies for aquaculture, food and for livestock fodder. All parts of plants can be utilized for foodstuff, compost, mulch, medicine, and for construction. Wetland Plants: A Source of Nutrition and Ethnomedicine aims to promote public understanding of this remarkable resource, exploring not only their role in the ecosystem but also their nutritional and medicinal purposes. Based on original research, the text focuses on species identification (with original pictures of wetland plants including morphological features), nutritive value and ethno-medicinal uses. This book serves as an important and basic reference material for further research into the basic biological as well as the applied medicinal aspects of traditional medicinal wetland plants.
    Materialart: Online-Ressource
    Seiten: XXIX, 228 p. 149 illus., 148 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030692582
    URL: https://doi.org/10.1007/978-3-030-69258-2
    DOI: 10.1007/978-3-030-69258-2
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 22
    Online-Ressource
    Online-Ressource
    Medicinal Plants of the Asteraceae Family : Traditional Uses, Phytochemistry and Pharmacological Activities (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Biochemistry. ; Plant Science. ; Chemical Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. An overview of medicinal plants of the Asteraceae family and their impact on human health -- Chapter 2. Artemisia annua L.: Traditional uses, Phytochemistry and Pharmacological activities -- Chapter 3. Artemisia indica Wild.: Ethnobotany, phytochemistry, pharmacological attributes and safety profile -- Chapter 4. Arnica montana L.: Traditional uses, bioactive chemical constituents, and pharmacological activities -- Chapter 5. Aster tataricus L.f.: Ethnomedicinal uses, phytochemistry and pharmacological activities -- Chapter 6.Atractylodes lancea (Thunb.) DC.: Ethnobotany, phytochemistry, pharmacological attributes and safety profile -- Chapter 7. Carthamus tinctorius L.: Traditional uses, phytochemistry and pharmacological activities -- Chapter 8.Chrysanthemum morifolium Ramat.: A Medicinal Plant with Diverse Traditional Uses, Bioactive Constituents, and Pharmacological Activities -- Chapter 9.Crassocephalum crepidioides (Benth.) S.Moore: Traditional uses, chemical constituents and biological activities -- Chapter 10. Dolomiaea costus (Falc.) Kasana & A. K. Pandey: Ethnomedicinal uses, bioactive chemical constituents and Pharmacological activities -- Chapter 11.Eclipta prostata (L.) L.: Traditional use, phytochemistry and pharmacology -- Chapter 12. Helianthus annuus L.: Traditional uses, phytochemistry and pharmacological activities -- Chapter 13. Silybum marianum (L.) Gaertn.: Traditional uses, phytochemistry and pharmacological activities.
    Kurzfassung: This book highlights 12 major plants in the Asteraceae family from the aspects of traditional uses as food and medicine, phytochemistry, and pharmacological activities. Asteraceae is one of the largest family of flowering plants comprising over 1,600 plant genera and 32,000 plant species. Plants belonging to this family have a long history of being used as medicinal plants for the treatment of various diseases. Many of them are also used in the preparation of foods, beverages, and also used in pharmaceutical and cosmetic industries. In addition, plants such as Artemisia annua have played an important role in the discovery of novel drugs. The book summarizes the traditional uses of the plants in the family Asteraceae and their scientific validation, which helps readers understand their relation and impact on human health. It also explains the Phytochemistry of the species and presents the pharmacological activities and mechanisms in detail. Understanding current scientific knowledge will help in the commercialization of products based on these plants and also helps to find the research gaps that should be fulfilled in the future for their optimal use. It also helps in increasing the awareness of the plant species related to conservation, cultivation, and sustainable utilization. This edited volume comprises chapters contributed by experts from around the world. .
    Materialart: Online-Ressource
    Seiten: IX, 230 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811960802
    URL: https://doi.org/10.1007/978-981-19-6080-2
    DOI: 10.1007/978-981-19-6080-2
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 23
    Online-Ressource
    Online-Ressource
    Heparanase : From Basic Research to Clinical Applications (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Oncology. ; Medicine Research. ; Biology Research. ; Cancer Biology. ; Oncology. ; Biomedical Research.
    Beschreibung / Inhaltsverzeichnis: Section 1: Historical Background -- Chapter 1: Mast cell/platelet heparanase/Heparan sulfate biosynthesis and turnover -- Chapter 2: gene cloning/overview -- Chapter 3: gene cloning/melanoma metastasis -- Chapter 4: gene cloning/cancer/immune system -- Chapter 5: heparin/HS modifying enzymes -- Section 2: Crystal Structure/substrate specificity/gene regulation -- Chapter 6: crystal structure -- Chapter 7: molecular dynamics, KKDC peptide -- Chapter 8: Biochemistry/active site -- Chapter 9: substrate specificity -- Chapter 10: gene regulation, promoter/Egr1/methylation -- Chapter 11: SNPs -- polymorphism -- Chapter 12: Splice variants -- Section 3: Cell & tumor biology (general functions & mode of action) -- Chapter 13: Exosomes/heparan sulfate/heparanse -- Chapter 14: Exosomes/drug resistance -- Chapter 15: Nuclear heparanse/transcriptional activity -- Chapter 16: Non-Enzymatic functions/Signal transduction/cellular trafficking/autophagy -- Chapter 17: Heparan sulfate/stem cells/inflammation -- Chapter 18: Danger signals/HS/platelet heparanse -- Chapter 19: Heparanse/Intergrins/Melanoma -- Section 3: Immune Cells/Immnuno-Modulation -- Chapter 20: Heparain. Heparanse and Selectins in Cancer Metastasis and Inflamation --- Chapter 21: Trans-Endithelial Migration, Lymphocytes, Neutrophils/T-cells --Chapter 22: Macrophages, dendritic cells, autoimmunity -- Chapter 23: Macrophages, Heparanse and the tumor microenvironment, neutralizing antibodies -- Chapter 24: NK Cells -- Section 4: Cancer (heparanse in specific types of cancer) -- Chapter 25: Myeloma, inhbition, drug resistance -- Chapter 26: Breast Cancer/Pancreatic Cancer/Cancer and Inflammation -- Chapter 27: Brain Metastasis/MIR-1258 -- Chapter 28: Gastric cancer/immunization -- Chapter 29: Head and Neck Cancer -- Chapter 30: Glioma -- Chapter 31: Sarcoma -- Section 5: Inhibitors/clinical trails/cancer -- Chapter 32: Chemistry/synthesis of heparanse inhibitors PI-88, PG -- Chapter 33: PG series/biology/Tumor models and clinical trial -- Chapter 34:Chemically modified heparins/Heparin mimetics -- Chapter 35: Medicinal Chemistry (Ronesparstat/small molecules/clinical trials) - Section 6: Other indications/diseases -- Chapter 36: IBD/inflammation and cancer/diabetes/obesity -- Chapter 37: Immune Diabetes -- Chapter 38 Inflammation, Sepsis/Amyloidosis -- Chapter 39: Kidney dysfunction -- Chapter 40: Fibrosis -- Chapter 41: Viral infection -- Chapter 42: Cariomyocytes/Endothelial cell-cardiomyocyte crosstakl in diabetic cariomyopathy -- Chapter 43: Eye research -- Chapter 44: atheroscelerosis, nuclear localization -- Chapter 45: Yona Nadir (coagulation/tissue factor) -- Section 7: Heparanse-2 (Hpa2) -- Chapter 46: Hpa2 gene cloning -- Chapter 47: UFS -- urofacial syndrome/peripheral neuropathy -- Chapter 48: Hpa2: tumor suppressor.
    Kurzfassung: Proteases and their involvement in cancer progression have been well addressed and documented; however, the emerging premise presented within this book is that Heparanase is a master regulator of aggressive cancer phenotypes and crosstalk with the tumor microenvironment. This endoglycosidase contributes to tumor-mediated remodeling of the extracellular matrix and cell surfaces, augmenting the bioavailability of pro-tumorigenic and pro-inflammatory growth factors and cytokines that are bound to Heparan sulfate. Compelling evidence ties Heparanase with all steps of tumor progression including tumor initiation, growth, angiogenesis, metastasis, and chemoresistance, supporting the notion that Heparanase is an important contributor to the poor outcome of cancer patients and a validated target for therapy. Unlike Heparanase, heparanase-2, a close homolog of Heparanase, lacks enzymatic activity, inhibits Heparanase, and regulates selected genes that promote normal differentiation and tumor suppression. Written by internationally recognized leaders in Heparanase biology, this volume presents a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications to scientists, clinicians and advanced students in cell biology, tumor biology and oncology.
    Materialart: Online-Ressource
    Seiten: XVIII, 885 p. 168 illus., 107 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030345211
    Serie: Advances in Experimental Medicine and Biology, 1221
    URL: https://doi.org/10.1007/978-3-030-34521-1
    DOI: 10.1007/978-3-030-34521-1
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 24
    Online-Ressource
    Online-Ressource
    Beyond IPM: Introduction to the Theory of Holistic Pest Management (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Microbiology. ; Zoology. ; Plant Science. ; Agriculture. ; Microbiology. ; Zoology.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction: Beyond IPM -- 2. The Nature of Integrated Pest Management -- 3. The Need for a Holistic Approach to Pest Management -- 4. Theoretical Support of Holistic Pest Management -- 5. Methods for analysis of Holistic Pest Management -- 6. Implementing Holistic Pest Management -- 7. Holistic Science in Pest Management: Winds of Change.
    Kurzfassung: About 15 years ago, we asked ourselves why the methods developed by the research institutions for the management of pests were almost not used by small landholder farmers. It seemed obvious to us that conventional pest control –called “Integrated Pest Management”– was based on a reductionist approach. In reviewing the literature on the subject, we found that our concern was not new or unique. The agreement of some authors with our ideas reinforced our efforts to find a holistic approach to pest management. We took two central ideas to develop the holistic approach: First, pest management actions must put the farmer at the center of the system. Second, pest management must consider not only both pests but the other important components of the system in question. This approach based on the farmers and the systems in which they are immersed, is called “Holistic Pest Management” or HPM. In this book, I present the philosophy and practice of HPM, a new paradigm of pest management.
    Materialart: Online-Ressource
    Seiten: XXX, 154 p. 34 illus., 8 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030433703
    Serie: Sustainability in Plant and Crop Protection, 15
    URL: https://doi.org/10.1007/978-3-030-43370-3
    DOI: 10.1007/978-3-030-43370-3
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 25
    Online-Ressource
    Online-Ressource
    New Nanomaterials and Techniques for Tumor-targeted Systems (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Nanotechnology. ; Medicine Research. ; Biology Research. ; Cancer Biology. ; Nanotechnology. ; Biomedical Research.
    Beschreibung / Inhaltsverzeichnis: 1 Introduction -- 2 Barriers for tumor drug delivery -- 3 Tumor-targeted strategies -- 4 Tumor-responsive drug release strategies -- 5 Tumor diagnosis patterns -- 6 Tumor therapeutic modes -- 7 Carbon-based tumor-targeted systems -- 8 Silica-based tumor-targeted systems -- 9 Lipid-based tumor-targeted systems -- 10 Dendrimer-based tumor-targeted systems -- 11 Polymer-based tumor-targeted systems -- 12 Other new tumor-targeted systems -- 13 Clinical applications of tumor-targeted systems -- 14 Challenges and perspectives of tumor-targeted systems.
    Kurzfassung: This book summarizes the latest advances in nanomaterials and techniques in the field of tumor-targeted diagnosis and therapy. It provides valuable information for beginners and senior researchers, and stimulates new research directions by offering novel and provocative insights into the properties and technical principles of nanomaterials. The book systemically discusses the challenges in tumor treatment, current tumor-targeted strategies, drug-release strategies, diagnosis and therapeutic patterns, and also explores newly developed multifunctional nanomaterials and related systems.
    Materialart: Online-Ressource
    Seiten: VI, 463 p. 72 illus., 63 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811551598
    URL: https://doi.org/10.1007/978-981-15-5159-8
    DOI: 10.1007/978-981-15-5159-8
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 26
    Online-Ressource
    Online-Ressource
    Sunlight, Vitamin D and Skin Cancer (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Dermatology. ; Oncology. ; Cancer Biology. ; Dermatology. ; Oncology.
    Beschreibung / Inhaltsverzeichnis: Section I: Introduction -- Lessons learned from paleolithic models and evolution for human health: a snap shot on beneficial effects and risks of solar radiation -- Section II: UV-induced cutaneous synthesis of vitamin D and the physiologic consequences (I) -- Sunlight, UV-radiation, vitamin D and skin cancer: how much sunlight do we need? -- Section III: Solar radiation, Vitamin D and human health -- Vitamin D status and cancer incidence and mortality -- Vitamin D receptors polymorphisms and cancer -- On the relationship between sun exposure and all-cause mortality -- Lindqvist PG (2020) Women with greater sun exposure habits seem to be healthier and to live longer. Are these results in contrast to other research? No -- Section IV: Epidemiology of skin cancer -- Epidemiology of skin cancer and UV radiation – update 2019 -- Solar UV exposure and mortality from skin tumors: an update -- Solarium Use and Risk for Malignant Melanoma: many open questions,not the time to close the debate -- Section V: Photocarcinogenesis of skin cancer -- Molecular biology of basal and squamous cell carcinomas -- Human papillomaviruses and skin cancer -- The immune system and pathogenesis of melanoma and nonnmelanoma skin cancer -- Section VI: The relevance of the vitamin D endocrine system for skin cancer -- Protection from ultraviolet damage and photocarcinogenesis by vitamin D compounds -- The role of classical and novel forms of vitamin D in the pathogenesis and progression of non-melanoma skin cancers -- The Vitamin D Receptor as tumor suppressor in skin -- Cancer prevention in skin and other tissues via cross-talk between vitamin D- and p53- signalling -- Section VII: Prevention and Management of Skin Cancer -- Sunscreens in the United States: Current Status and Future Outlook -- A handful of sunscreen for whole body application -- Sunlight, vitamin D and Xeroderma pigmentosum -- Update: Solar UV-radiation, vitamin D and skin cancer surveillance in organ transplant recipients (OTRs) -- Section VIII: UV-induced cutaneous synthesis of vitamin D and the physiologic consequences – II. promise and outlook -- Ultraviolet exposure scenarios: balancing risks of erythema and cutaneous vitamin D synthesis -- The Paleolithic nutrition model in relation to ultraviolet light and vitamin D -- Index.
    Kurzfassung: The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‑exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
    Materialart: Online-Ressource
    Seiten: XIV, 428 p. 83 illus., 28 illus. in color. , online resource.
    Ausgabe: 3rd ed. 2020.
    ISBN: 9783030462277
    Serie: Advances in Experimental Medicine and Biology, 1268
    URL: https://doi.org/10.1007/978-3-030-46227-7
    DOI: 10.1007/978-3-030-46227-7
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 27
    Online-Ressource
    Online-Ressource
    Cancer Stem Cells: New Horizons in Cancer Therapies (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Stem cells. ; Oncology. ; Medical microbiology. ; Cancer Biology. ; Stem Cell Biology. ; Oncology. ; Medical Microbiology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction to cancer stem cells -- Chapter 2. Types of Cancer Stem Cells -- Chapter 3. Isolation and Characterization of Cancer Stem Cells (CSCs) -- Chapter 4. Lung and Prostate Cancer Stem Cells -- Chapter 5. A differential role of miRNAs in regulation of breast cancer stem cells -- Chapter 6. Skin stem cells in cancer -- Chapter 7. Ocular Cancer stem cells: Advances in therapeutic interventions -- Chapter 8. Cancer Stem Cells and Tumour Aggressiveness -- Chapter 9. Therapeutic Implication of Cancer Stem Cells.-Chapter 10. Glioblastoma stem cells as a therapeutic target -- Chapter 11. Cancer stem cells and therapeutic angiogenesis -- Chapter 12. Cancer stem cells as a seed for cancer metastasis -- Chapter 13. Functionality of intron specific genes and cancer stem cells in the progression of colorectal cancer -- Chapter 14. Technological advancement in Cancer Stem Cell Research -- Chapter 15. Controversies in Isolation and Characterization of Cancer Stem Cells -- Chapter 16. Targeting therapies for cancer stem cells -- Chapter 17. Targeting Cancer stem cells by nanoenabled drug delivery -- Chapter 18. Cancer Stem Cells in Patients Survival and Therapies in Cancer.-.
    Kurzfassung: This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer. It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression. The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeutic rationale.
    Materialart: Online-Ressource
    Seiten: VII, 369 p. 65 illus., 58 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811551208
    URL: https://doi.org/10.1007/978-981-15-5120-8
    DOI: 10.1007/978-981-15-5120-8
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 28
    Online-Ressource
    Online-Ressource
    The Flax Genome (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Plant Science. ; Genetics and Genomics. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: Reference genome sequence of flax -- Repeat DNA sequences in flax genomes -- Pale flax (Linum bienne): an underexplored flax wild relative -- Flax breeding -- QTL mapping: strategy, progress and prospects in flax -- Genetics of abiotic stress in flax. QTL and candidate genes for flax disease resistance -- Key stages of flax bast fiber development through the prism of transcriptomics -- Metabolomics and transcriptomics-based tools for linseed improvement.
    Kurzfassung: The Flax Genome is a comprehensive compilation of most recent studies focused on reference genome, genetic resources and molecular diversity, breeding, QTL mapping, gene editing tools, functional genomics and metabolomics, molecular breeding via genomic selection, and genomic resources. The flax genome reference sequences and the new genome assemblies are presented. A list of flax QTL and candidate genes associated with more than 35 traits, including yield and agronomic, seed quality and fatty acid composition, fibre quality and yield, abiotic stress, and disease resistance traits, are summarized. A QTL- based genomic selection strategy and genome–editing tools are systematically introduced. In addition, huge amounts of flax genomic resources generated in the last decade are summarized. The book contains 13 chapters with about 390 pages authored by globally reputed researchers in the relevant fields to this crop The book is intended to be useful to students, teachers, and researchers interested in traditional and molecular breeding, pathology, molecular genetics and breeding, bioinformatics and computational biology, and functional genomics.
    Materialart: Online-Ressource
    Seiten: XII, 294 p. 74 illus., 70 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031160615
    Serie: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-031-16061-5
    DOI: 10.1007/978-3-031-16061-5
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 29
    Online-Ressource
    Online-Ressource
    Progress in Botany Vol. 82 (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Forestry. ; Botanical chemistry. ; Biotic communities. ; Plant genetics. ; Plant physiology. ; Plant Science. ; Forestry. ; Plant Biochemistry. ; Ecosystems. ; Plant Genetics. ; Plant Physiology.
    Beschreibung / Inhaltsverzeichnis: 1.Tools Shape Paradigms of Plant-Environment Interactions -- 2.Gene Expression in Coffee -- 3. Cross-Talk Between Sporophyte and Gametophyte During Anther and Ovule Development In Angiosperms -- 4. The Photosynthetic System in Tropical Plants Under High Irradiance and Temperature Stress -- 5. Plant Peroxisomes and Their Metabolism of ROS, RNS, and RSS -- 6. Ammonium Assimilation and Metabolism in Rice -- 7. How can we Interpret the Large Number and Diversity of Abscisic Acid Transporters? -- 8. Orient in the World with a Single Eye: The Green Algal Eyespot and Phototaxis -- 9. Bidirectional Lateral Transport Barriers in Serving Plant Organs and Integral Plant Functioning: Localized Lignification, Suberinization, and Cutinization -- 10. The Haustorium of Phytopathogenic Fungi: A Short Overview of a Specialized Cell of Obligate Biotrophic Plant Parasites -- 11. Transmission of Phloem-Limited Viruses in the Host Plants by Their Aphid Vectors -- 12. Biotechnology for Biofuel Production -- 13. Modelling Urban Tree Growth and Ecosystem Services: Review and Perspectives.
    Kurzfassung: With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. This latest volume includes reviews on plant physiology, biochemistry, genetics and genomics, forests, and ecosystems.
    Materialart: Online-Ressource
    Seiten: XII, 464 p. 76 illus., 44 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030686208
    Serie: Progress in Botany, 82
    URL: https://doi.org/10.1007/978-3-030-68620-8
    DOI: 10.1007/978-3-030-68620-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 30
    Online-Ressource
    Online-Ressource
    RNA-Based Technologies for Functional Genomics in Plants (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Plant genetics. ; Physiology. ; Plant Science. ; Plant Genetics. ; Physiology.
    Beschreibung / Inhaltsverzeichnis: Artificial Small RNAs for Functional Genomics in Plants -- Use of mRNA-interactome capture for generating novel insights into plant RNA biology -- Improving nutrient value of crops: Applications of RNAi in targeting plant metabolic pathways -- Utilizing RNA-based approaches to understand plant-insect interactions.
    Kurzfassung: This book offers a unique and comprehensive overview of key RNA-based technologies, as well as their development and applications for the functional genomics of plant coding and non-coding genes. It focuses on the latest as well as classical RNA-based techniques used for studies on small RNAs, long non-coding RNAs and protein-coding genes. These techniques chiefly focus on target mimics (TMs) and short tandem target mimics (STTMs) for small RNAs, and artificial microRNAs (amiRNAs), RNA interference (RNAi) and CRISPR/Cas for genes. Furthermore, the book discusses the latest trends in the field and various modifications of the above-mentioned approaches, and explores how these RNA-based technologies have been developed, applied and validated as essential technologies in plant functional genomics. RNA-based technologies, their mechanisms of action, their advantages and disadvantages, and insights into the further development and applications of these technologies in plants are discussed. These techniques will enable the users to functionally characterize genes and small RNAs through silencing, overexpression and editing. Gathering contributions by globally respected experts, the book will appeal to students, teachers and scientists in academia and industry who are interested in horticulture, genetics, pathology, entomology, physiology, molecular genetics and breeding, in vitro culture & genetic engineering, and functional genomics. .
    Materialart: Online-Ressource
    Seiten: XIII, 428 p. 48 illus., 44 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030649944
    Serie: Concepts and Strategies in Plant Sciences,
    URL: https://doi.org/10.1007/978-3-030-64994-4
    DOI: 10.1007/978-3-030-64994-4
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 31
    Online-Ressource
    Online-Ressource
    Agrochemicals in Soil and Environment : Impacts and Remediation (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Agronomy. ; Biotechnology. ; Nanotechnology. ; Plant Science. ; Agriculture. ; Agronomy. ; Biotechnology. ; Nanotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Agrochemicals in Soil and Environment: An Overview -- Chapter 2. Agrochemicals- Provenance, Environmental Fate and Remediation Measures -- Chapter 3. Impact of Agrochemicals on Soil Microbiota -- Chapter 4. Agriculture Pollution in Kerala, India with Special Reference to Endosulphan -- Chapter 5. An Intergenerational Community-Based Approach to Safe Farming and Environmental Health -- Chapter 6. Guidance on Pesticides Handling in Farming -- Chapter 7. Impact of Pesticides, Herbicides and Insecticides on the Ecosystem -- Chapter 8. Pesticides and its Effects on Plants: A Case Study of Deltamethrin -- Chapter 9. The Use of Glyphosate in Regions of Argentina and Colombia and its Socio-environmental Impacts -- Chapter 10. Impact of Insecticides on Soil and Environment and their Management Strategies -- Chapter 11. Role of Insect Pest Management in Agriculture Conservation -- Chapter 12. Mobility of Trace Elements in Agricultural Soils- Chapter 13. The effects of nutrient enrichment on nutrient-poor ecosystems: Insights from the study of serpentine soil plant relations -- Chapter 14. Soil Erosion and Sedimentation - A Source of Contamination and Impact on Agriculture Productivity -- Chapter 15. Plastics in the Soil Environment: An Overview -- Chapter 16. Lead and cadmium contamination in the soil environment: Impacts on plant growth and human health -- Chapter 17. Heavy metals contamination on farmlands in the crude oil exploration area -- Chapter 18. Effect of Trace Elements in Soils and Its Management -- Chapter 19. Remediation of Agrochemicals in Soil and Environment -- Chapter 20. Alleviation in the Toxicity of Heavy Metals on Agricultural Crops by Metal Resistant Bacteria -- Chapter 21. Bioremediation Strategies to Mitigate the Impact of Atrazine in the Environment: Recent Advances and Prospects. Chapter 22. Aspergillus Mediated Bioremediation of Agrochemicals- Current Progress and Future Perspectives -- Chapter 23. Implications of Phytohormones as Agro-chemicals under Dynamic Environmental Conditions -- Chapter 24. Role of Genetically Modified Bacteria for Alleviating of Agrochemical Impact on the Environment -- Chapter 25. ‘Omics Perspective’ - Molecular Blue-print for Agrochemical Remediation -- Chapter 26. Impact and Remediation of Agrochemicals in Soil and Environment: Conclusions and Future Perspectives.
    Kurzfassung: This volume ‘Agrochemicals in Soil and Environment: Impacts and Remediation’ is a comprehensive collection of important literature on agrochemical contamination. The main focus of this book is to point out undesirable changes in biological, physical and chemical characteristics of agricultural soils and its impacts on global agricultural crop productivity. Soil is one of the important resources of basic needs for our sustenance but due to various anthropogenic activities like urbanization and industrialization, the soil is losing its basic quality characteristics. Soil microorganisms, water holding capacity, minerals, salts and nutrients are under the direct threat due to agrochemicals therefore, agricultural sector is facing a serious challenge. Lack of proper knowledge and luxurious applications of agrochemicals resulting into degradation and deterioration of soil quality, loss of soil and crop productivity and threatening the food security. Therefore, it is imperative to develop indices, indicators and soil parameters for the monitoring and impact assessment of agricultural contaminants. Further, biotic and abiotic stresses and their tolerance mechanisms in plants in relation to the soil contaminants such as toxic pollutants, heavy metals, inorganic and organic matters, variety of pesticides, insecticides, herbicides, agricultural runoffs and solid wastes, and chemical fertilizers are also highlighted in this volume. This book also discusses causes of reduced agriculture productivity and suggests sustainable measures such as plant-based technologies, bioremediation and nanotechnology, that can be used to overcome the crop losses. The book is interest to research students, teachers, agricultural scientists, agronomists, environmentalists as well as policy makers.
    Materialart: Online-Ressource
    Seiten: XXVI, 612 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811693106
    URL: https://doi.org/10.1007/978-981-16-9310-6
    DOI: 10.1007/978-981-16-9310-6
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 32
    Online-Ressource
    Online-Ressource
    Skin Cancer: Pathogenesis and Diagnosis (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Biomedical engineering. ; Biochemical markers. ; Nanomedicine. ; Cancers. ; Biomedical Engineering and Bioengineering. ; Biomarkers. ; Cancer Nanotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Cancer of the Skin:Type and Etiology -- Chapter 2. Therapeutic intervention in skin cancer: Future prospects -- Chapter 3. Melanin Based Classification of Skin Types and Their Susceptibility to UV-induced Cancer -- Chapter 4. The Epidemiology of Skin Cancer Worldwide -- Chapter 5. UV-R induced Vitamin D synthesis and skin cancer -- Chapter 6. The role of microbiome in the induction, diagnosis and therapy of skin cancer -- Chapter 7. Skin Cancer: Molecular Biomarker for Diagnosis, Prognosis, Prevention and Targeted Therapy -- Chapter 8. Therapeutics intervention of skin cancer in the OMICS era -- Chapter 9. Artificial intelligence in Skin Cancer: Diagnosis and Therapy -- Chapter 10. Biomedical engineering in cancer diagnosis and therapy -- Chapter 11. Skin cancer treatment with Emphasis on Nanotechnology -- Chapter 12. Non-long coding RNA and role in skin cancer diagnosis and therapy -- Chapter 13. Potential of long non-coding RNAs in the diagnosis and therapy of melanoma skin cancer.-.
    Kurzfassung: This book highlights the molecular and cellular mechanisms involved in the initiation and progression of skin cancer. It also explains the role of the environment in skin cancer development and explores the potential of microbiome in the diagnosis, prevention and treatment of skin cancer. The book also presents potential biomarkers for early detection of skin cancer and discusses recent advances in skin cancer prevention and treatment using photodynamic therapy. Lastly, it summarizes the applications of biomedical engineering, non-coding and nanotechnology in the diagnosis and therapeutics in skin cancer. It is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, and dermatologists.
    Materialart: Online-Ressource
    Seiten: VIII, 250 p. 27 illus., 20 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811603648
    URL: https://doi.org/10.1007/978-981-16-0364-8
    DOI: 10.1007/978-981-16-0364-8
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 33
    Online-Ressource
    Online-Ressource
    Freshwater Red Algae : Phylogeny, Taxonomy and Biogeography (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Ecology . ; Water. ; Hydrology. ; Plant Science. ; Ecology. ; Water. ; Water. ; Water.
    Beschreibung / Inhaltsverzeichnis: History of freshwater red algae; taxonomic diversity and phylogeny; biogeographic trends; how to collect freshwater red algae; scope and organization of this book -- Subphylum Cyanidiophytina: Class Cyanidiophyceae; Subphylum Proteorhodophytina: Classes Compsopogonophyceae, Porphyridiophyceae, Rhodellophyceae and Stylonematophyceae -- Subphylum Eurhodophytina: Classes Bangiophyceae and Florideophyceae (Subclasses Corallinophycidae, Hildenbrandiophycidae and Rhodymeniophycidae) -- Subphylum Eurhodophytina: Class Florideophyceae, Subclass Nemaliophycidae, Orders Acrochaetiales, Balbianiales and Thoreales -- Subphylum Eurhodophytina: Class Florideophyceae, Subclass Nemaliophycidae, Order Batrachospermales.
    Kurzfassung: This book presents the phylogeny, taxonomy and biogeography of freshwater red algae. Its content is divided into five chapters. The first chapter provides a brief history of freshwater red algal research, habits and collecting methods, general biogeographic trends and an overview of the taxonomic/phylogenetic placement of freshwater taxa. The other four chapters are taxonomic treatments of non-marine red algae based on taxonomic levels, i.e. classes within the phylum Rhodophyta, orders within each class, families within each order, and genera within each family. Descriptions, phylogenetic data (including numerous trees), geographic range (maps for most species) and dichotomous keys for identification are presented. Comprehensive data are provided for more than 220 species.
    Materialart: Online-Ressource
    Seiten: XII, 338 p. 113 illus., 112 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030839703
    URL: https://doi.org/10.1007/978-3-030-83970-3
    DOI: 10.1007/978-3-030-83970-3
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 34
    Online-Ressource
    Online-Ressource
    Genetic Polymorphism and cancer susceptibility (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Genetics. ; Medical genetics. ; Cancers. ; Genetics and Genomics. ; Medical Genetics. ; Cancer Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Polymorphisms and Mutation: What is difference? -- Chapter 2. Single nucleotide polymorphisms and pharmacogenomics -- Chapter 3. Impact of MicroRNA Polymorphisms on Breast Cancer Susceptibility -- Chapter 4. From inflammation to cancer: Role of genetic polymorphisms of Inflammatory Pathway Molecules in Gastric Cancer -- Chapter 5. Colorectal Cancer and genetic polymorphism in key regulatory low penetrance genes -- Chapter 6. Role of Genetic Polymorphisms in Breast Cancer -- Chapter 7. Genetic Polymorphisms of Essential Immune Pathogenic Response Genes and Risk of Cervical Cancer -- Chapter 8. Thyroid Cancer and genetic polymorphism -- Chapter 9. SNPs of TLRs and Bladder Cancer -- Chapter 10. Role of genetic polymorphisms in Lung Cancer.
    Kurzfassung: This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.
    Materialart: Online-Ressource
    Seiten: XXI, 339 p. 48 illus., 46 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789813366992
    URL: https://doi.org/10.1007/978-981-33-6699-2
    DOI: 10.1007/978-981-33-6699-2
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 35
    Online-Ressource
    Online-Ressource
    Opuntia spp.: Chemistry, Bioactivity and Industrial Applications (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Food science. ; Plant Science. ; Food Science.
    Beschreibung / Inhaltsverzeichnis: 1-Introduction to Opuntia spp.: Chemistry, bioactivity and Industrial Applications -- 2-South African perspective on Opuntia spp.: cultivation, human and livestock food and industrial applications -- 3-Ethnobotany, medicinal utilization and Systematics of Opuntia species from Deserts of Pakistan -- 4-Cactus Pear (Opuntia spp.) Species and Cultivars -- 5-Classification, Distribution and Morphological Characterization of Opuntia species -- 6-Cultivation and Cultural Practices of Opuntia spp -- 7-Molecular characterization of Opuntia spp -- 8-Genetic diversity and ecotypes of Opuntia spp -- 9-Potential attribute of crassulacean acid metabolism of Opuntia spp. production in water-limited conditions -- 10-Harvest and Postharvest Technology of Opuntia spp -- 11-Chemistry and functionality of Opuntia spp. nopal cladodes -- 12-Opuntia ficus-indica (L.) Mill. Bioactive Ingredients and Phyto-constituents -- 13-Opuntia Fiber and its Health-Related Beneficial Properties -- 14-Opuntia spp. chemical constituents and bioactive compounds, with particular regards to polyphenols -- 15-Profile and Biological Properties of the main Phenolic compounds in cactus pear (Opuntia spp.) -- 16-Opuntia spp. essential oils -- 17-Antioxidant activity of Opuntia spp.: A review -- 18-Natural antimicrobial molecules from Opuntia spp. and their role in poultry nutrition -- 19-Genus Opuntia: A golden source of compounds with anti-inflammatory potential -- 20-Opuntia spp. benefits in chronic diseases -- 21-Traceability of Opuntia spp -- 22-Antidiabetic Activity of Opuntia spp -- 23-Anticancer Activity of Opuntia spp -- 24-Innovative technologies for the identification of chemical and bioactive compounds in Opuntia spp. plant, food and waste -- 25-Innovation technologies for extracting Opuntia spp. seed oil -- 26-Novel pectins from prickly pear (Opuntia albicarpa) fruits: structural features and rheological properties -- 27-Modern Technologies in Opuntia spp. Juice Processing -- 28-Novel Technologies in Juice Processing from Opuntia spp. Fruits -- 29-Potential use of prickly pear juice prepared from shelf-grown cultivars as an authentic and nutritional fruit supplement -- 30-Fermented Beverages from Opuntia species: Composition, Commercialization and Future Outlook -- 31-Opuntia spp. Marmalade -- 32-Opuntia pear peel as a source of functional ingredients and their utilization in meat products -- 33-Opuntia spp. Seed Oil -- 34-Prickly pear (Opuntia ficus indica) processing by extrusion-cooking -- 35-Opuntia spp. and Extruded Food Products -- 36-Opuntia spp. Extruded Food Products -- 37-Industrial uses of Opuntia spp. by-products -- 38-Bread Enrichment with Opuntia spp. Derivatives -- 39-Opuntia spp. products and by-products as a potential source of edible films and coatings -- 40-Microencapsulation technology: an alternative preservation method for Opuntia spp. derived products and their bioactive compounds -- 41-Prickly pear (Opuntia spp.) in animal and poultry feed -- 42-Industrial applications of Opuntia spp. (nopal, fruit and peel) -- 43-Opuntia spp. as a source of sugars for the ethanol production -- 44-Opuntia spp. in biogas production -- 45-Opuntia spp. in dye-sensitized solar cells -- 46-Incorporation of Opuntia spp. into Food Systems -- 47-Opuntia spp. in cosmetics and pharmaceuticals -- 48-Food and non-food applications of Opuntia spp. seed oil -- 49-Opuntia spp. in the textile industry -- 50-Cactus pear as colorants and coloring foods: application in different food matrices.
    Kurzfassung: The Opuntia fruits, commonly known as cactus pears or prickly pears, have been suggested by the Food and Agriculture Organization to be a promising and strategic crop in regions suffering from lack of water. In Mexico, India, South Africa, and the Mediterranean, the Opuntia fruits have become popular due to their nutritive value and health-promoting benefits, including antioxidant, antiulcerogenic and antiatherogenic traits and protective effects against LDL oxidation. Additionally, readily absorbable sugars, high vitamin C and mineral content, and a pleasant flavour make Opuntia tailor-made for novel food. Due to their ecological advantages, high functional value, and health-related traits, Opuntia fruits can be highly exploited in different food processing applications. For instance, Opuntia cactus fruits are used for the preparation of juices and marmalades; Opuntia cactus plants are used to feed animals in African and Latin American countries; Peruvian farmers cultivate Opuntia cactus for growing the cochineal (Dactylopius coccus) insect and producing the natural dye carmine; and the commercial production of food and non-food products from Opuntia has been established in Mexico, USA and several Mediterranean countries. Opuntia spp.: Chemistry, Bioactivity and Industrial Applications creates a multidisciplinary forum of discussion on Opuntia cactus with special emphasis on its horticulture, post-harvest, marketability, chemistry, functionality, health-promoting properties, technology and processing. The text includes detailed discussion of the impact of traditional and innovative processing on the recovery of high-added value compounds from Opuntia spp. by-products. Later chapters explore the potential applications of Opuntia spp. in food, cosmetics and pharmaceutical products.
    Materialart: Online-Ressource
    Seiten: XIX, 1059 p. 98 illus., 46 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030784447
    URL: https://doi.org/10.1007/978-3-030-78444-7
    DOI: 10.1007/978-3-030-78444-7
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 36
    Online-Ressource
    Online-Ressource
    Fruits of the Brazilian Cerrado : Composition and Functional Benefits (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Botanical chemistry. ; Food science. ; Medicine, Preventive. ; Health promotion. ; Agriculture. ; Plant Science. ; Plant Biochemistry. ; Food Science. ; Health Promotion and Disease Prevention. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: 1. Acrocomia aculeata -- 2. Attalea dubia & Attalea phalerata -- 3. Campomanesia genus -- 4. Caryocar spp -- 5. Mauritia flexuosa -- 6. Dipteryx alata -- 7. Solanum lycocarpum -- 8. Attalea speciosa -- 9. Syagrus romanzoffiana -- 10. Hancornia speciosa.
    Kurzfassung: Fruits of the Brazilian Cerrado: Composition and Functional Benefits describes the nutritional, chemical and physical characteristics of the fruits of the Cerrado, as well as their pharmacological effects and use in phytotherapics. Chapters are dedicated to the morphological characteristics, macronutrients, micronutrients and active compounds of various fruits, with separate sections covering their peels, leaves, nuts, pulps, and other components. The text also includes detailed studies on the treatment of diseases with these natural products, as well as their applications in popular use by local communities. Authors explain the importance of bioactive compounds found in the fruits and their possible mechanisms of action in the organism. This text thus provides a valuable reference to researchers studying a range of topics, including functional foods, phytotherapy, and plant science.
    Materialart: Online-Ressource
    Seiten: XIII, 186 p. 31 illus., 21 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030629496
    URL: https://doi.org/10.1007/978-3-030-62949-6
    DOI: 10.1007/978-3-030-62949-6
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 37
    Online-Ressource
    Online-Ressource
    Medicinal and Aromatic Plants of India Vol. 1 (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Agronomy. ; Plant diseases. ; Plant Science. ; Agronomy. ; Plant Pathology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. History of medicinal plants research in India -- Chapter 2. Importance of medicinal and aromatic plants in our day-to-day life -- Chapter 3. Major diseases of important medicinal and aromatic plants An Indian subcontinent perspective -- Chapter 4. Introduction to MAPs in India : Distribution , diversity and conservation and uses -- Chapter 5. Diversity of MAPs in India and its potential -- Chapter 6. Ethnomedicinal , phytochemistry and pharmacological properties of Arnebia species -- Chapter 7. Diversity of medicinal and aromatic plants with special reference to endemic plants of India -- Chapter 8. Distribution, chemical composition and ethnomedicinal appraisal of endangered medicinal plants of Kashmir Himalaya , India -- Chapter 9. Chemical diversity and ethnobotanical survey of Indian MAP species -- Chapter 10. Traditional uses of medicinal and aromatic plants among Indian tribes -- Chapter 11. Opportunities and challenges in ethnobotanical survey of Indian medicinal and aromatic plants -- Chapter 12. Breeding of MAPs in India : Achievements and prospects -- Chapter 13. Conservation of wild MAPs : Constraints achievements and prospects -- Chapter 14. Quality assurance and quality control of MAPs in India -- Chapter 15. Chromatographic analysis of medicinal plants for quality control -- Chapter 16. Expanding horizones : Role of biotechnology in MAP research, production and utilization -- Chapter 17. Role of biotechnology in MAP research, production and utilization -- Chapter 18. Integrated transcriptomics and proteomics approaches to study secondary metabolic pathways in medicinal plants: Recend trends -- Chapter 19. Demand and use of medicinal plants of India -- Chapter 20. Major diseases of medicinal and aromatic plants : An overview of constraints in production and management strategies -- Chapter 21. Role of medicinal and aromatic plants in the cosmetic industry -- Chapter 22. Harbouring the potential of medicinal and aromatic plants of India: A biotechnological approach -- Chapter 23. Quality assurance of cultivated and aromatic plants : Good agricultural and collection practices (GAP and GCP) -- Chapter 24. Breeding and Germplasm preservation of medicinal and aromatic plants of India.
    Kurzfassung: This book is the 8th volume of the popular series ‘Medicinal and Aromatic Plants of the World’. Like the previous volumes, this volume is being introduced in a monographic format containing an extremely rich and diverse medicinal flora of India. Both well-known and somewhat still ignored species have been described in view of their traditional, present day and prospective uses. The scientific and technological achievements are also included aptly in this volume, together with a careful and critical consideration to our contemporary knowledge of this vast interdisciplinary domain with an Indian focus. In the era of global climate change and pandemics, building on the huge Indian traditions, this volume will make an important contribution to the better knowledge and understanding of MAPs. The Indian flora has always been recognized for its medicinal and aromatic plant values and this volume is explicitly focusing in that direction. With the rapidly expanding scope of natural nutraceuticals and herbal formulations, this book will be a fruitful acquisition for the interested readers globally.
    Materialart: Online-Ressource
    Seiten: XVIII, 430 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030987015
    Serie: Medicinal and Aromatic Plants of the World, 8
    URL: https://doi.org/10.1007/978-3-030-98701-5
    DOI: 10.1007/978-3-030-98701-5
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 38
    Online-Ressource
    Online-Ressource
    The Amaranth Genome (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Genome and Transcriptome of Amaranth Species -- Chapter 2. Organelle Genomics: The Chloroplast Genome of Amaranth -- Chapter 3. Genetic and Phenotypic Odyssey: Voyage of the Grain Amaranths from the Americas to the Old World -- Chapter 4. Genetics of Betalain Pigments in Amaranth Species -- Chapter 5. Molecular Characterization of Seed Storage Proteins (SSPs) in Grain Amaranth -- Chapter 6. Genetic Diversity in Amaranth and its Close Relatives -- Chapter 7. Searching for an Identity: Functional Characterization of Taxonomically Restricted Genes in Grain Amaranth -- Chapter 8. How to Overcome Recalcitrance? Novel Strategies and Recent Advances in the Genetic Transformation of Grain Amaranth -- Chapter 9. Polyploidy and Hybridization for Amaranth Crop Improvement -- Chapter 10. Amaranth Transcription Factors in Response to Biotic and Abiotic Stresses.
    Kurzfassung: This book describes the development of genetic resources in amaranths, with a major focus on genomics, reverse, and forward genetics tools and strategies that have been developed for crop improvement. Amaranth is an ancient crop native to the New World. Interest in amaranths is being renewed, due to their adaptability, stress tolerance, and nutritional value. There are about 65 species in the genus, including Amaranthus caudatus L., A. cruentus L., and A. hypochondriacus L., which are primarily grown as protein-rich grains or pseudocereals. The genus also includes major noxious weeds (e.g., A. palmeri). The amaranths are within the Caryophyllales order and thus many species (e.g., A. tricolor) produce red (betacyanin) or yellow (betaxanthin) betalain pigments, which are chemically distinct from the anthocyanins responsible for red pigmentation in other plants. A. hypochondriacus, which shows disomic inheritance (2n = 32; n= 466 Mb), has been sequenced and annotated with 23,059 protein-coding genes. Additional members of the genus are now also been sequenced including weedy amaranths, other grain amaranths, and their putative progenitors.
    Materialart: Online-Ressource
    Seiten: XVII, 181 p. 53 illus., 45 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030723651
    Serie: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-72365-1
    DOI: 10.1007/978-3-030-72365-1
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 39
    Online-Ressource
    Online-Ressource
    Circulating Tumor Cells : Advances in Liquid Biopsy Technologies (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Cancer Therapy. ; Tumour Biomarkers.
    Beschreibung / Inhaltsverzeichnis: Part 1. CTC Technologies -- Affinity -- Physical -- ctDNA -- miRNA -- Exosomes -- Part 2 -- Biology of CTC -- Dormancy -- Culture -- EMT -- ctDNA and Exosomes -- Cells in circulation with CTC -- Part 3 -- CTC Analysis -- IHC, FISH, and other molecular assays -- Functional characterization -- Advanced microscopy and AI -- Analysis of non-cellular circulating markers -- Part 4 -- Clinical Applications of the Liquid Biopsy -- Early detection and cancer screening -- Prognosis and therapeutic monitoring -- Applications in Clinical Trials -- Applications in Drug Development.
    Kurzfassung: It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other emerging aspects of the liquid biopsy, including circulating tumor DNA and methylated DNA (ctDNA, ct meDNA), ctRNA, ct miRNA, circulating tumor proteins (and other) biomarkers and circulating tumor derived exosomes (ctExosomes).
    Materialart: Online-Ressource
    Seiten: XXI, 668 p. 77 illus., 72 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031229039
    Serie: Current Cancer Research,
    URL: https://doi.org/10.1007/978-3-031-22903-9
    DOI: 10.1007/978-3-031-22903-9
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 40
    Online-Ressource
    Online-Ressource
    The Brassica juncea Genome (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Brassica juncea: A Crop for Food and Health -- Chapter 2. Botanical Descriptions of Brassica juncea: Taxonomy, Cytology, Cytogenetics and Phylogenetic Relationships -- Chapter 3. Chemical Composition of Oil and Cake of Brassica juncea: Implications on Human and Animal Health -- Chapter 4. Genepools of Brassica -- Chapter 5. Genetic Diversity Characterization and Population Structure in Brassica juncea -- Chapter 6. Classical Genetics and Traditional Breeding in Brassica juncea -- Chapter 7. Heteroploidy in Brassica juncea: Basics and Applications -- Chapter 8. Introgression Breeding in Brassica juncea -- Chapter 9. In vitro Culture for Micropropagation, Somatic Embryogenesis, Somatic Mutation, and Somatic Hybridization in Brassica juncea -- Chapter 10. Genetic Modification of Brassica juncea: Current Scenario and Future Prospects -- Chapter 11. Molecular Linkage Mapping in Brassica juncea: Founding the basis for Marker Assisted Selection -- Chapter 12. Brassica juncea Genome Sequencing: Structural and Functional Insights -- Chapter 13. Brassica juncea Genome Assemblies – Characteristics and Utilization -- Chapter 14. Resequencing in Brassica juncea for Elucidation of Origin and Diversity -- Chapter 15. Large Scale Genome Analysis: Genome Sequences, Chromosomal Reorganization, and Repetitive DNA in Brassica juncea and Relatives -- Chapter 16. Brassica juncea L. : Chloroplast Genome -- Chapter 17. Transcriptomics Research and Resources in Brassica spp -- Chapter 18. Metabolomics of Brassica juncea -- Chapter 19. Proteomics Approach to Uncoverkey Signaling Pathways in Brassica juncea in Abiotic and Biotic stress -- Chapter 20. Genomics Approaches to Understand the Evolution of Brassica juncea -- Chapter 21. Regulatory Genes in Development and Adaptation, and Their Utilization in Trait Improvementin Brassica juncea: Challenges and Opportunities -- Chapter 22. Advanced Molecular Breeding for Yield -- Chapter 23. Advanced Breeding for Oil and Oil Cake Quality in Brassica juncea -- Chapter 24. Advances in Breeding Strategies for Improving Stress Tolerance in Brassicas -- Chapter 25. Genome Editing in Polyploid Brassica Crops.
    Kurzfassung: This book is the first comprehensive compilation of deliberations on elucidation and augmentation of the genome of Brassica juncea, one of the leading oilseed crops of the world, popularly called as brown mustard, Indian mustard, Chinese mustard, or Oriental mustard. It includes discussions on genepools; genetic diversity and its characterization; classical genetic and traditional breeding; basics and application of heteroploidy; techniques and applications of introgressive hybridization; in vitro culture for micro-propagation, somatic mutation, somatic embryogenesis, and somatic hybridization; genetic engineering including genetic transformation and gene silencing; and molecular genetic mapping and mapping of genes and comprehensive delineations on genome sequencing and comparative genomics; resequencing for elucidation of origin and diversity; large-scale genome analysis; plastid genome sequence; transcriptomics; metabolomics; proteomics; evolutionary genomics; role of regulatory genes in development and adaptation and their utilization in trait improvement; precise breeding for yield, quality, and resistance to biotic and abiotic stresses; and prospects of genome editing.
    Materialart: Online-Ressource
    Seiten: XXXVII, 491 p. 36 illus., 31 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030915070
    Serie: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-91507-0
    DOI: 10.1007/978-3-030-91507-0
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 41
    Online-Ressource
    Online-Ressource
    Immuno-Oncology Crosstalk and Metabolism (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Tumors Immunological aspects. ; Cancer Treatment. ; Biochemistry. ; Metabolism. ; Cell biology. ; Immunology. ; Cancer Biology. ; Cancer Microenvironment. ; Tumour Immunology. ; Cancer Therapy. ; Metabolic Pathways. ; Immunology.
    Beschreibung / Inhaltsverzeichnis: 1 Cancer Metabolism and Aggressive Tumor Behaviour -- 2 Immune Cell Metabolism and Function -- 3 Cancer Cell Metabolism Effecting Immune function -- 4 Immune Cell Metabolites as Fuel for Cancer Cells -- 5 Immuno-Onco metabolism and Resistance to Therapy -- 6 Targeting Immuno-Onco metaolism in Cancers -- 7 Timing of the major metabolic switches in immune cell activation and differentiation during cancer development.
    Kurzfassung: This book discusses the novel metabolic cross-talk between immune and tumor cells in the tumor microenvironment that promotes their growth and progression. It also describes deregulated metabolism in cancer cells that promotes suppressive and cancer cell-favourable microenvironment. Further, the book provides novel insights on the metabolic changes in immune cells that promote tumor cell growth and survival. In turn, it also reviews the involvement of immuno-onco metabolic cross-talk in the development of resistance to chemo-radiation therapy (CRT) in tumor cells. Lastly, it also explores the potential of immuno-oncology metabolism as a therapeutic approach against tumor cells.
    Materialart: Online-Ressource
    Seiten: X, 218 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811662263
    URL: https://doi.org/10.1007/978-981-16-6226-3
    DOI: 10.1007/978-981-16-6226-3
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 42
    Online-Ressource
    Online-Ressource
    Dietary Research and Cancer (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Biology. ; Cancer Treatment. ; Biotechnology. ; Molecular biology. ; Physiology. ; Cancer Biology. ; Biological Sciences. ; Cancer Therapy. ; Biotechnology. ; Molecular Biology. ; Physiology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction to Dietary Research and Cancer -- Chapter 2. Healthy Dietary Patterns and Cancer -- Chapter 3. Frequently Asked Diet and Nutrition Related Questions by Cancer Survivors -- Chapter 4. Dietary Recommendations of Worldwide Cancer Related Organizations -- Chapter 5. Outcome of ‘Diet and Cancer’ Related Clinical Trials -- 6. Diet and Cancer Epigenetics: A Step Towards Developing Cancer Epigenetic Diet -- 7. Role of Dietary Ingredients on Expression of Oncogenic and Tumor Suppressor miRNA -- 8. Can Diet Influence Metastasis? -- 9. Impact of Dietary Interventions on Cancer Stem Cells -- 10. Interaction of Dietary Metabolites with Anti-cancer Drug Targets -- 11. Revisiting the Anticancer Drug-Food Interactions -- 12. Functional Foods, Nutraceuticals, and Dietary Supplements in Cancer Prevention -- 13. Do Antioxidants Really Help Cancer Patients? The Puzzle of Benefits and Perils -- 14. Market of Dietary Supplements: Analysis of Health Benefits and Risk in Cancer -- 15. Cancer and Fasting: Can Fasting/Calorie Restriction (CR) or Fasting Mimicking Diet (FMD) Helps Fight Cancer? Molecular Basis of Fasting Response -- 16. Do Fasting, CR, and FMD Improves the Chemotherapy Response, Reduce Off Target Toxicities and Enhance Antitumor Immunity? Illusion or Clinical Reality? -- 17. Future Prospectus of Dietary Interventions in the Integrated Management of Cancer.
    Kurzfassung: This book reviews all important aspects of dietary research associated with cancer with the aim of shedding new light on these conditions through combined understanding of traditional and new paradigms. The book is divided into 17 chapters, the first portion reinterprets healthy diets for cancer based on up-to-date evidence from a network science perspective, examining the dietary patterns, outcome of diet related clinical trials, emerging framework of molecular mechanisms and interactions of dietary interventions and their applications in personalized diet, ground realities of benefits and regulatory frame work for functional foods, nutraceuticals and supplements in cancer prevention and upcoming future prospectus in diet-cancer research.. The later part of the book discusses recent advances in understanding of the elaborative discourse on cancer and fasting, covering, for example, calorie restriction and fasting mimicking diet. Finally, different Dietary research and approaches are considered in the context of novel intervention for cancer research. Dietary Research in Cancer will be of interest for all researchers, nutritionists, students and clinicians in the field.
    Materialart: Online-Ressource
    Seiten: XX, 197 p. 57 illus., 16 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811660504
    URL: https://doi.org/10.1007/978-981-16-6050-4
    DOI: 10.1007/978-981-16-6050-4
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 43
    Online-Ressource
    Online-Ressource
    Pharmacovigilance for Herbal and Traditional Medicines : Advances, Challenges and International Perspectives (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Alternative medicine. ; Pharmacovigilance. ; Plant Science. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance.
    Beschreibung / Inhaltsverzeichnis: Adverse effects of herbal medicines -- Interactions between herbal and conventional medicines -- Molecular basis of herbal adverse drug reactions (ADRs) -- Detecting and assessing signals of herbal safety concerns -- Spontaneous reporting of suspected herbal ADRs: national and global perspectives -- Herbal-sector: initiated schemes for reporting herbal ADRs -- Industry and regulatory perspectives on herbal ADRs and ADR reporting -- Applying pharmacoepidemiological methods to investigating safety of herbal medicines -- Impact of traditional herbal medicinal products directive on pharmacovigilance of herbal medicines -- Communication of herbal safety concerns -- Risk management strategies for herbal medicines -- Pharmacogenomics and herbal medicines -- Nomenclature and quality of herbal medicines. .
    Kurzfassung: This remarkable new book is the first text dedicated to the topic of pharmacovigilance for herbal and traditional medicines. Taking a truly global perspective, this volume draws together contributions from a diverse group of experts, writing on current knowledge and practices in pharmacovigilance for herbal and traditional medicines, and on advances and innovation in monitoring the safety of this unique and complex category of products and preparations. In part one, the book discusses the current status of pharmacovigilance for herbal and traditional medicines, including the importance of natural products chemistry to harms, and its relevance in considering how pharmacovigilance for these products could be undertaken. Several other chapters discuss methodological approaches and ongoing challenges in pharmacovigilance for herbal and traditional medicines, including issues relating to nomenclature, coding and classification, and the nuances involved in causality assessment. Part two of the book focusses on pharmacovigilance for herbal and traditional medicines around the world, with chapters from authors in several different countries representing diverse historical, ethnic, cultural, social and political contexts. These chapters provide deeper insights and perspectives into spontaneous reporting for herbal and traditional medicines in those countries, and in the context of the local use, practice and regulatory landscape for these products. Part two also provides an overview and new analysis of international case safety reports for herbal medicines held in VigiBase (the World Health Organization's global database of individual case safety reports, maintained by the Uppsala Monitoring Centre). This book is aimed at pharmacists, doctors, nurses and other health professionals, herbal-medicine practitioners and organisations, herbal medicine and pharmaceutical industry personnel, pharmacovigilance specialists, medicines’ regulators, health and social science researchers and academics, pharmacovigilance and health professional students, and students of herbal and traditional medicine, throughout the world. It is an extremely valuable resource for all individuals whose work touches the intersection between herbal medicines and pharmacovigilance, and it provides both an introduction to the topic and a deeper, comprehensive, contemporary account of the topic.
    Materialart: Online-Ressource
    Seiten: XXII, 409 p. 22 illus., 16 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031072758
    URL: https://doi.org/10.1007/978-3-031-07275-8
    DOI: 10.1007/978-3-031-07275-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 44
    Online-Ressource
    Online-Ressource
    The Moso Bamboo Genome (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Economic Value and Research Significance of Moso Bamboo -- Chapter 2. Moso Bamboo Germplasm Resources in China/World -- Chapter 3. Biological Traits of Moso Bamboo -- Chapter 4. Moso Bamboo Genome -- Chapter 5. Moso Bamboo Transposon -- Chapter 6. Transcriptome of Moso Bamboo -- Chapter 7. Moso Bamboo Alternative Splicing (AS ) and Polyadenylation -- Chapter 8. Characterizations and Function of Transcript Factor Gene families -- Chapter 9. MicroRNAs of Moso Bamboo -- Chapter 10. Mitochondrial Genome of Endophytic Fungi from the Seed of Moso Bamboo -- Chapter 11. Breeding Strategies of Moso Bamboo.
    Kurzfassung: This book is the first comprehensive compilation describing the botanical traits, genetic resources, whole genome sequencing, Mitochondrial genome, transcriptomes of different organs with developmental stages, transcription factors, delineating gene evolution of gene family in Bambusoideae, alternative splicing (AS) and polyadenylation, case studies for economically important traits such as internode length, shoot fast growing, flowering, ageing and stress-resistant genes and small RNAs-mediated gene regulation of moso bamboo flowering and other developmental stages. Applications of transcriptome and genome approaches in moso bamboo in general and the prospects of transgenic breeding and genome editing technologies in bamboo are also discussed. Altogether, the book comprises eleven chapters covered over 200 pages authored by the researchers involved in genomic science, molecular biology, and breeding. This book appeals to graduate students, post-graduate students, research scholars, researchers, and industry players in the field of plantation bamboo in general, bamboo processing and bamboo garden owner and fans of bamboo culture in particular.
    Materialart: Online-Ressource
    Seiten: XXII, 208 p. 124 illus., 110 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030808365
    Serie: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-80836-5
    DOI: 10.1007/978-3-030-80836-5
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 45
    Online-Ressource
    Online-Ressource
    Latin American Blackberries Biology : Mora de Castilla (Rubus glaucus Benth.) Vol 1 (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Biomolecules. ; Physical biochemistry. ; Macromolecules. ; Plant Science. ; Agriculture. ; Structural Biology.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction -- 2. Floral morphology and phenology -- 3. Pollen grain morphology, viability, and insect visitation -- 4. The phenology of Rubus glaucus Benth. characterized by the BBCH scale -- 5.Propagation and cultivation -- 6.Fruit and chromosome number -- 7.Post-harvest physiology and nutritional facts -- 8.Genetic diversity -- 9.Breeding programs -- 10.Morphological diversity -- 11.Rubus glaucus and climate change.
    Kurzfassung: The current book focuses on Mora de Castilla (Rubus glaucus Benth.). It explores aspects, such as origin, phenology, propagation, floral and fruit morphology, arthropod visitors, pollination mechanisms, propagation methods, chromosome number, fruit development, breeding, morphological diversity, and the impact of climate change. It includes novel data about plant phenology, flowering, insect visitors, seed germination, fruit morphology, and allometric relationships. This work includes an in-depth review of the most recently published information on the topic. Mora de Castilla is an economically important fruit crop from the Andes. It has been crossed with other Rubus species due to its high yield and everbearing habit. Currently, it is an economically important plant. It has been hybridized with other Rubus species producing new and better-quality hybrids This book contains numerous photographs selected by the author to provide the reader with detailed information about the plant´s morphological features and arthropod visitors. .
    Materialart: Online-Ressource
    Seiten: XVIII, 178 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031317507
    URL: https://doi.org/10.1007/978-3-031-31750-7
    DOI: 10.1007/978-3-031-31750-7
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 46
    Online-Ressource
    Online-Ressource
    Biomes of the Southern Hemisphere (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Botany. ; Ecology . ; Biodiversity. ; Biotic communities. ; Population biology. ; Plant Science. ; Ecology. ; Biodiversity. ; Community and Population Ecology.
    Beschreibung / Inhaltsverzeichnis: 1 -- Introduction -- 2. Southern tropical and subtropical rainforests -- 3. Multi-faced southern seasonal tropics 3.1 Heterogeneity of the savanna biomes: a southern perspective -- 4. Southern mediterranean: an extratropical plant marvel -- 5. Dry face of the ‘wet hemisphere’: southern deserts and semideserts -- 6. Austral temperate forests: a biome-classification conundrum -- 7. Southern ‘steppes’ and other grassy oddballs -- 8. The biomes of the coldest corners of the World -- 9. Synthesis: A New Global Zonobiome System -- 10. Further Challenges and Research Agenda -- References.
    Kurzfassung: This is the first comprehensive and critical evaluation of the biome (large-scale, functional biotic communities) patterns in the Southern Hemisphere. Revising the Heinrich Walter's zonobiome system for the Southern Hemisphere appeared as necessary because of the bioclimatic imbalance between the Hemispheres. This revision resulted in formulation of a new zonobiome system, considering the geographic peculiarities of both Hemispheres, hence creating a new, powerful tool of global nature-resource survey and conservation. The system has a potential to attract the interest of the global climate modeling community as the concept of biome (and associated hierarchical system) has a strong functional focus. All zonal biomes of the Southern Hemisphere are featured, and the major challenges we face in understanding their origins, structure, and functioning are discussed. The book contains a wealth of original data resulting from collation of bioclimatic data and vegetation mapping.
    Materialart: Online-Ressource
    Seiten: XIV, 219 p. 71 illus., 69 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031267390
    Serie: Biome Ecology, 1
    URL: https://doi.org/10.1007/978-3-031-26739-0
    DOI: 10.1007/978-3-031-26739-0
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 47
    Online-Ressource
    Online-Ressource
    Biodiesel from Flowering Plants (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Anatomy. ; Biotechnology. ; Plant Science. ; Anatomy. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2. History of Biodiesel -- Chapter 3. Anacardiaceae -- Chapter 4. Apocynaceae -- Chapter 5. Arecaceae -- Chapter 6. Asteraceae -- Chapter 7. Betulaceae -- Chapter 8. Brassicaceae -- Chapter 9. Caryocaraceae -- Chapter 10. Chrysobalanaceae -- Chapter 11. Clusiaceae -- Chapter 12. Combretaceae -- Chapter 13. Compositae -- Chapter 14. Cornaceae -- Chapter 15. Cucurbit -- Chapter 16. Cyperaceae -- Chapter 17. Dipterocarpaceae -- Chapter 18. Euphorbiaceae -- Chapter 19. Fabaceae -- Chapter 20. Irvingiaceae -- Chapter 21. Linaceae -- Chapter 22. Magnoliaceae -- Chapter 23. Malvaceae -- Chapter 24. Meliaceae -- Chapter 25. Nyssaceae -- Chapter 26. Oleaceae -- Chapter 27. Papavaraceae -- Chapter 28. Pedaliaceae -- Chapter 29. Poaceae -- Chapter 30. Putranjivaceae -- Chapter 31. Rosaceae -- Chapter 32. Rutaceae -- Chapter 33. Salicaceae -- Chapter 34. Salvadoraceae -- Chapter 35. Sapindaceae -- Chapter 36. Sapotaceae -- Chapter 37. Schisandraceae -- Chapter 38. Simaroubaceae -- Chapter 39. Simmondsiaceae -- Chapter 40. Solanaceae -- Chapter 41. Sterculiaceae -- Chapter 42. Theaceae -- Chapter 43. Zygophyllaceae -- Chapter 44. Catalyst for Transesterification -- Chapter 45. Standards for Biodiesel.
    Kurzfassung: This book offers an exhaustive coverage of process modifications in biodiesel production from oil drawn from 84 oleaginous plant species occurring in all parts of the world, thereby enlisting the scope and potential of many new and non-conventionally obscure plant sources. Biodiesel, now prepared from major vegetable oils, has become a compulsion to offset the dwindling reserve of petro-diesel, which naturally intrudes into the cooking oil demand. This has necessitated search for new sources. The book consolidates the biodiesel production from oils being extracted from conventional plants and also from a plethora of new and non-conventional plants along with their habit and habitats, history of biodiesel’s invention, explanation on species-wise biodiesel process variables, catalytic inclusions, global standards, fuel properties varying with species, blending benefits, cost effectiveness, shelf life, ignition characteristics, fuel consumption and engine performances with eco-friendly exhaust. This book is of immense use to teachers, researchers, scientists of climatology and carbon footprint, energy consultants, fuel chemists, students of agriculture and forestry, automobile engineering, industrial chemistry, environmental sciences and policy makers or anyone who wishes to scale up the biodiesel industry.
    Materialart: Online-Ressource
    Seiten: XXIV, 675 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811647758
    URL: https://doi.org/10.1007/978-981-16-4775-8
    DOI: 10.1007/978-981-16-4775-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 48
    Online-Ressource
    Online-Ressource
    The Citron Compendium : The Citron (Etrog) Citrus medica L.: Science and Tradition (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Judaism. ; Religion and science. ; Arts. ; Plant Science. ; Judaism. ; Religion and Sciences. ; Arts.
    Beschreibung / Inhaltsverzeichnis: The Biology of the Citron -- Citron Genomics -- Citron Phytochemistry -- Selected Aspects of Commercial Production in Etrog Orchards -- Preserving Etrog Quality After Harvest: Doctrine and Practice -- Citron Arthropod Pests in the Mediterranean, Their Origin and Notes On Their Biology and Management -- Diseases of the Etrog Citron and Other Citrus Trees -- The Citron ( Citrus medica L.) in China -- The Citron in Italy and Its cultivation in Calabria -- The Citron in Corsica -- The Citron in the United States -- The Citron in Mediterranean Food and Beverages -- 'Fruit of the Goodly Trees’: The Talmudic Discourse on the Etrog Citron -- From Theophrastus to the Present: The Citron in Medicine -- The Etrog Citron in Art -- The Etrog Citron in Midrashic and Kabbalistic Literature -- From ‘An Etrog’ to ‘One's Etrog’: A Literary Analysis of S.Y. Agnon’s Story -- History of the Citron in Ancient Israel and the Near East -- The Etrog Citron Trail to the North: Genoa and Trieste -- The Corfu Etrog Citron Polemic -- The Grafted Etrog Citron Controversy -- Etrog Citrons of the Land of Israel in Modern Times.
    Kurzfassung: This comprehensive book covers the theoretical and practical aspects of citron trees and fruit. The citron (Citrus medica L.), one of the three primary species ancestral to most citrus types, is used for traditional medicine and is highly revered in the Jewish religion during the Tabernacles feast, referred to by the name 'Etrog'. This book’s three sections address biology (botany, genomics, Chinese and Mediterranean citrons, diseases, pests, and horticulture), tradition (Talmudic discourse, mysticism, medicine, literature, art, food, and beverages) and history (archaeology, trade, grafting controversies); these sections are supplemented by a glossary and pictorial album. The 22 chapters, some new and some translated and considerably expanded from the 2018 Hebrew edition, were written by world-renowned specialists from Israel, Italy, France, the U.S.A., China and Australia. The book is written in an accessible scientific style aimed at a wide range of readers. .
    Materialart: Online-Ressource
    Seiten: XVIII, 607 p. 228 illus., 196 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031257759
    URL: https://doi.org/10.1007/978-3-031-25775-9
    DOI: 10.1007/978-3-031-25775-9
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 49
    Online-Ressource
    Online-Ressource
    Plant-Based Therapeutics, Volume 1 : Cannabis sativa (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Alternative medicine. ; Pharmacology. ; Medicinal chemistry. ; Physiology. ; Agriculture. ; Plant Science. ; Complementary and Alternative Medicine. ; Pharmacology. ; Medicinal Chemistry. ; Physiology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 The History of Cannabis -- Chapter 2 The Bioactive Components of Plants -- Chapter 3 Chemical Constituents of Cannabis -- Chapter 4 The Bioactive Components of Cannabis -- Chapter 5 Neurological Effects of Cannabis -- Chapter 6 Psychotropic Effects of Cannabis -- Chapter 7 The Analgesic effects of Cannabis -- Chapter 8 Cannabis and Perinatal Development -- Chapter 9 Cannabis and Multiple Sclerosis -- Chapter 10 Cannabis and Cancer -- Chapter 11 Cannabis and Parkinson’s disease -- Chapter 12 Cannabis and the Skin -- Chapter 13 Antiviral Activities of Cannabis -- Chapter 14 Alkaline Phosphatase Stimulation.
    Kurzfassung: By examining historical applications of the compounds found in plants, this five-volume series serves as a reference for quality assurance, research, product development, and regulatory guidance of the compounds found in plant-based medicines. This work supports the growing consumers' interest in herbal medicine for wellness and health. Plant-Based Therapeutics, Volume 1: Cannabis sativa, the first in the series, covers a unique plant species and provides the framework to integrate its evidence-based scientific discoveries with healthcare therapies. Cannabis has been used in religious ceremonies and medical purposes for thousands of years. Cannabidiol (CBD), the main non-psychoactive component of Cannabis, was isolated in the 1940s, and its structure was established in the 1960s. In 1964 tetrahydrocannabinol (THC), the psychoactive component, was isolated. Cannabis has more than 500 components, of which 104 cannabinoids have been identified. Two of them, THC and CBD, have been the primary components of scientific investigations. They were approved by the FDA for chemotherapy-induced nausea and vomiting in 1985; for appetite stimulation in wasting conditions, such as AIDS, in 1992, and in 2018 for treating two forms of pediatric epilepsy, Dravet syndrome and Lennox-Gastaut syndrome. Beyond the indications for which cannabinoids are FDA-approved, the evidence reveals that cannabinoid receptors are present throughout the body, embedded in cell membranes, and are believed to be more numerous than any other receptor system. When cannabinoid receptors are stimulated, a variety of physiologic processes ensue. Thus, other constituents of Cannabis are extremely promising either as individual compounds or their potential synergistic or entourage effects in the treatment of numerous medical conditions. .
    Materialart: Online-Ressource
    Seiten: XXI, 657 p. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031351556
    URL: https://doi.org/10.1007/978-3-031-35155-6
    DOI: 10.1007/978-3-031-35155-6
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 50
    Online-Ressource
    Online-Ressource
    Genomic Designing for Abiotic Stress Resistant Oilseed Crops (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Genomic Designing For Abiotic Stress Tolerant Soybean -- Designing the Rapeseed Genome for Abiotic Stress Tolerance -- Sunflower and Abiotic Stress: Genetics and Breeding for Resistance in the Post-Omics Era -- Integration of Genomics Approaches in Abiotic Stress Tolerance in Groundnut (Arachis hypogaea L.): An overview -- Drought Tolerance in Rape and Mustard: Conventional and Molecular Approaches -- Genomic Designing For Sesame Resistance To Abiotic Stresses -- Abiotic Stresses in Castor Plant -- Designing Genomic Solutions to Enhance Abiotic Stress Resistance in Flax.
    Kurzfassung: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in oilseed crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The eight chapters each dedicated to a oilseed crop in this volume elucidate on different types of abiotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Materialart: Online-Ressource
    Seiten: XXIII, 283 p. 18 illus., 16 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030900441
    URL: https://doi.org/10.1007/978-3-030-90044-1
    DOI: 10.1007/978-3-030-90044-1
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 51
    Online-Ressource
    Online-Ressource
    Baccharis : From Evolutionary and Ecological Aspects to Social Uses and Medicinal Applications (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Ecology . ; Conservation biology. ; Botanical chemistry. ; Plant physiology. ; Pharmacology. ; Plant Science. ; Ecology. ; Conservation Biology. ; Plant Biochemistry. ; Plant Physiology. ; Pharmacology.
    Beschreibung / Inhaltsverzeichnis: Part I: Ecological and Evolutionary pathways -- Chapter 1: The Ecological and Applied Potential of Baccharis -- Chapter 2: Baccharis: Diversity and Distribution -- Chapter 3: The Evolution of Genetic Studies of Baccharis -- Chapter 4: Intersexual Differences in Demography, Resource Investment, and Herbivory in Baccharis -- Chapter 5: Multitrophic and Indirect Interactions in the Baccharis dracunculifolia System -- Chapter 6: Endophytic Fungi of Baccharis -- Chapter 7: Baccharis as Nurse Plants -- Chapter 8: Biological Invasion by Baccharis -- Part II: Structure and Chemistry of Baccharis -- Chapter 9: Morpho-anatomical Characteristics of Species of Baccharis -- Chapter 10: Essential Oils of Baccharis: Chemical Composition and Biological Activities -- Chapter 11: Flavonoids of Baccharis -- Chapter 12: Chemistry and Biological Activities of Phenolic Compounds from Baccharis Genus -- Chapter 13: Baccharis Terpenoid Compounds -- Chapter 14: Macrocyclic Trichothecenes of Baccharis -- Chapter 15: Livestock Intoxication by Baccharis -- Part III: Baccharis: Applications and Innovations -- Chapter 16: An Overview of the Cultural and Popular Use of Baccharis -- Chapter 17: CPQBA 1: First Cultivar Registered and Protected From a Brazilian Medicinal Plant -- Chapter 18: Perspectives of Baccharis Secondary Metabolites as Sources for New Anticancer Drug Candidates -- Chapter 19: Innovation and Knowledge of Prospective Studies on the Genus Baccharis -- Part IV: Propolis of Baccharis -- Chapter 20: Chemical Constituents and Antioxidant Properties of Green Propolis -- Chapter 21: Possible Role of Propolis-derived Components in the Prevention and Treatment of Obesity and Diabetes -- Chapter 22: Effects of the Green Propolis on the Immune Response -- Chapter 23: From Innovation to Market: an Analysis of the Propolis Production Chain.
    Kurzfassung: This book has a broad scope and provides a comprehensive overview of the most up-to-date knowledge of the plant genus Baccharis. The book is organized into four major topics encompassing the evolution, ecology, chemistry, as well as environmental and medical applications of the genus. This publication is a major reference for an audience of practising researchers, academics, PhD students, and other scientists in a wide-ranging collection of fields, from Sociology to Medicine to bioeconomy.
    Materialart: Online-Ressource
    Seiten: XIX, 578 p. 137 illus., 79 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030835118
    URL: https://doi.org/10.1007/978-3-030-83511-8
    DOI: 10.1007/978-3-030-83511-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 52
    Online-Ressource
    Online-Ressource
    Fundamentals of Field Crop Breeding (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Genetics. ; Biotechnology. ; Plant Science. ; Agriculture. ; Genetics and Genomics. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Breeding Field Crops – History, Current Status And Introspections -- Chapter 2: Wheat Breeding -- Chapter 3: Rice Breeding -- Chapter 4: Maize Breeding -- Chapter 5: Barley Breeding -- Chapter 6: Pearl Millet Breeding. Chapter 7: Sorghum Breeding. Chapter 8: Small Millets Breeding -- Chapter 9: Sugarcane Breeding -- Chapter 10: Jute Breeding -- Chapter 11: Cotton Breeding -- Chapter 12: Maintenance Breeding Of Pusa Basmati Varieties -- Chapter 13: Maintenance Breeding -- Chapter 14: Efficient Breeding Of Crop Plants -- Chapter 15: Brassica Breeding -- Chapter 16: Groundnut Breeding -- Chapter 17: Soybean Breeding -- Chapter 18: Castor Breeding -- Chapter 19: Sunflower Breeding -- Chapter 20: Chickpea Breeding -- Chapter 21: Pigeonpea Breeding -- Chapter 22: Mungbean Breeding -- Chapter 23: Urdbean Breeding -- Chapter 24: Lentil Breeding -- Chapter 25: Fieldpea Breeding -- Chapter 26: Lathyrus Breeding.
    Kurzfassung: This book is an advanced textbook and a reference book for the post-graduate plant-breeding students and the plant breeders. It consolidates fundamental concepts and also the latest advances in plant-breeding practices including development in crop genomics. It contains crop wise explanation on origin, reproduction, genetics of yield contributing traits, biotic and abiotic stresses, nutritional improvement and crop specific plant-breeding procedures and techniques. The chapters are planned to describe crop-focused breeding procedure for the major crop plants as per their economic importance. The recent developments in breeding of field crops have been reported. The recent progress made in mapping traits of economic importance has been critically reviewed for each crop. The progress made in markers assisted selected in few crops has been summarized. This book bridges the knowledge gap and bring to the researchers and students information on modern breeding tools for developing biotic and abiotic stress tolerant, climate resilient and micronutrient rich varieties of field crops. The chapters in book are contributed by experienced Plant Breeders.
    Materialart: Online-Ressource
    Seiten: XIV, 1389 p. 109 illus., 98 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811692574
    URL: https://doi.org/10.1007/978-981-16-9257-4
    DOI: 10.1007/978-981-16-9257-4
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 53
    Online-Ressource
    Online-Ressource
    Cancer Neuroscience (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Cancer Treatment. ; Neurosciences. ; Immunotherapy. ; Cancer Biology. ; Cancer Therapy. ; Neuroscience. ; Cancer Microenvironment. ; Immunotherapy.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2. Neuronal influence on cancer initiation and growth -- Chapter 2.1 Paracrine signaling in CNS primary tumors and brain metastases -- Chapter 2.2 Paracrine signaling in PNS primary tumors -- Chapter 3. Neuronal influence on cancer invasion and metastasis including perineurial invasion -- Chapter 4. Neurotrophic activity of tumors -- Chapter 5. Cancer interactions with Schwann cells -- Chapter 6. Cancer-glial interactions -- Chapter 7. Neuron-cancer synaptic and other electrical signaling -- Chapter 8. Neuro-immune interactions system and immuno-oncology -- Chapter 9. Nervous system interactions with non-immune elements in the cancer microenvironment -- Chapter 10. Cancer-induced remodeling of the nervous system -- Chapter 11. Cancer and pain -- Chapter 12. Systemic interactions of cancer and the impact on the nervous system -- Chapter 13. Tools and model systems to study nerve-cancer interactions -- Chapter 14. Conclusions and Future Directions.
    Kurzfassung: This volume is the first on the market to address and discuss the emerging field of cancer neuroscience. Edited by pioneers in the field with contributions from top researchers, the volume serves as a comprehensive overview of the role of nerves in tumorigenesis and cancer progression. Chapters will address how the innervation of tumors can serve as both prognostic and predictive biomarkers as well as actionable therapeutic targets. Authors will describe current research efforts, and future directions for study and translation to the clinic. It is becoming increasingly apparent that certain treatments will need to consider interactions between the nervous system and cancer, and the novel concepts presented in the book address related accumulating evidence regarding therapeutic strategies. This unique volume will be useful for cancer researchers, neuroscientists, cancer biologists, oncologists, and others looking to gain a greater understanding of this emerging field.
    Materialart: Online-Ressource
    Seiten: XII, 202 p. 21 illus., 20 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031324291
    URL: https://doi.org/10.1007/978-3-031-32429-1
    DOI: 10.1007/978-3-031-32429-1
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 54
    Online-Ressource
    Online-Ressource
    Medicinal Plants: Biodiversity, Biotechnology and Conservation (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Biodiversity. ; Plant biotechnology. ; Plant Science. ; Biodiversity. ; Plant Biotechnology.
    Beschreibung / Inhaltsverzeichnis: 1. The Current Status of Population Extinction and Biodiversity Crisis of Medicinal Plants -- 2. Medicinal Plants and Bioactive Phytochemical Diversity: A Fountainhead of Potential Drugs against Human Diseases -- 3. Threats and opportunities for sustainable use of medicinal plants in Brazilian Atlantic Forest based on the knowledge of Indigenous Peoples and Local Communities -- 4. Climate Change Impact on Medicinal Plants: An Insight from the IUCN Red List Of Threatened Species -- 5. Securing Conservation Status of Paris Polyphylla, a Medicinally Important Plant of the Indian Himalayan Region -- 6. Endophytic Fungal Diversity in Solanaceous Medicinal Plants and Their Beneficial Impact -- 7. Genetic Studies on Threatened Medicinal Plants of Brazil: Mind the Gap -- 8. Medicinal Plants of North-east India: Biodiversity and Their Ethno-Medicinal Values -- 9. Strategies for Conservation and Sustainable Use of Medicinal Plants -- 10. Scientific Databases for Conservation of Medicinal Plants -- 11. International Trade of Medicinal and Aromatic Plants (MAPs) -- 12. Inventorization of Ecology, Ethnobotany and Conservation Status of Dactylorhiza hatagirea: Problems Progress and Prospects -- 13. Conservation and Sustainable Use of Medicinal Plants -- 14. Traditional Practices of Ethnomedicinal Plants in North-East Region of India and Their Conservation for Sustainable Utilization -- 15. Occurrence and Diversity of Major Naphthoquinones in Higher Plants: Their Distribution and Conservation Strategies -- 16. Astragalus fridae genetic Source,Applications, and Conservation -- 17. Tinospora cordifolia as a Potential Candidate for Health Care Of Post-Menopausal Women -- 18. The Potential Role of Medicinal Plants, Traditional Herbal Medicines and Formulations to Overcome SARS-CoV-2 Induced Health Crisis -- 19. Bioactive Compounds from Medicinal Plants and Its Therapeutic Uses in the Traditional Health Care System -- 20. In-Vitro conservation and propagation of endangered Ethno-Medicinal Orchids from the Northeast Region of India -- 21. Artificial Seed Production and Cryopreservation Technology for Conservation of Plant Germplasm with Special Reference to Medicinal Plants -- 22. Biotechnological Studies on Nasturtium Officinale (Watercress) - An Endangered Species of Significant Relevance in Medicine, Cosmetic, and Food Industries -- 23. Isatis tinctoria L. (woad) – Cultivation, Phytochemistry, Pharmacology, Biotechnology, and Utilization -- 24. Tissue Culture Techniques to Conserve Endangered Medicinal Plants with Antimicrobial and Antiviral Activities -- 25. Insights into the In Vitro Approaches for the Production of Secondary Metabolites Towards The Conservation of Medicinal Orchids -- 26. Biotechnological Approaches for Ex Situ Conservation of Medicinal Plants -- 27. Conservation of Medicinal Plants by Tissue Culture Techniques -- 28. Current Status of Metabolic Engineering of Medicinal Plants for Production of Plant-derived Secondary Metabolites -- 29. Stationary, Agitated and Bioreactor Cultures of Verbena officinalis L. (Common Vervain) - A Potential Rich Source of Bioactive Phenolic Compounds for Pharmacy, Health Food Industry and Cosmetology.
    Kurzfassung: This contributed volume provides a comprehensive, in-depth and subject-based reviews on the current status of active ingredients, sustainable use, biodiversity and conservation of certain endangered medicinal plants. The book also explores conventional and non-conventional biotechnological interventions for their biodiversity conservation. Medicinal plants have been used in worldwide as a major source of raw material for the traditional herbal healthcare practices as well as for drug discovery and development in pharmaceutical industry. The cumulative consequences of various human activities and environmental factors cause decline in the biodiversity of medicinal plants at an unprecedented rate worldwide. Thus, the overall understanding of ecology, species and genetic diversity along with assessment of the status of different threats and their impact on medicinal plants is crucial to sustain existing biodiversity, its utilization and conservation. All the latest advancements in the biotechnological approaches for the conservation research of endangered medicinal plants and the future perspectives have been described. This book provides comprehensive reviews spreading over about 25 chapters divided in three sections. The chapters of this book are written by recognized scientists in their respective fields which are useful to students, academicians, researchers, botanists, biotechnologists, policy makers, conservationists and industries interested in biodiversity conservation and medicinal plant research for the production of secondary metabolites.
    Materialart: Online-Ressource
    Seiten: XIX, 906 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811999369
    Serie: Sustainable Development and Biodiversity, 33
    URL: https://doi.org/10.1007/978-981-19-9936-9
    DOI: 10.1007/978-981-19-9936-9
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 55
    Online-Ressource
    Online-Ressource
    Aspects of Brazilian Floristic Diversity : From Botany to Traditional Communities (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Biodiversity. ; Plant ecology. ; Conservation biology. ; Ecology . ; Plant Science. ; Biodiversity. ; Plant Ecology. ; Conservation Biology.
    Beschreibung / Inhaltsverzeichnis: Flowering phenology in a restinga community: seven years of study -- Dioecy: the dimorphic sexual system and pollination in restinga vegetation -- Male and female sterility in flowering plants -- Broad-scale variation of phytoplankton richness in Brazilian inland waters -- The Importance of Palynology to Taxonomy -- Ecological Palynology -- Scientific Exploration Commission (1859-1861): Freire Allemão and the invisible network of collaborators -- The former Imperial Plant Nursery of Quinta da Boa Vista -- Medicinal plants used in Quilombola communities in Piranga, State of Minas Gerais, Brazil -- From mulungu to mamulengo”: The sharing of knowledge among teachers, academic researchers and mamulengueiros (traditional puppeteers) in a participatory workshop -- Biocultural heritage through museological narrative as a way of return on research in historical ethnobotany -- Conclusion of the reflections on Aspects of Brazilian Floristic Diversity: From Botany to Traditional Communities.
    Kurzfassung: Aspects of Brazilian Floristic Diversity: From Botany to Traditional Communities offers a unique approach in floristic diversity of the Neotropical region, specifically encompassing the Brazilian flora. This volume combines both theoretical and applied aspects of scientific making knowledge in different perspectives of Botanical Science. In this volume, botanical specialists discuss the many different approaches of taxonomic, reproductive, ecological and ethnobotanical aspects of Brazilian floristic diversity, thereby enlightening the global interest in Neotropical species, in particular those from the Brazilian territory. The book addresses relevant questions from many points of view, including anatomy, reproduction, palinology, conservation and ethnobotany, creating an in-depth perception of the flora in its complexity constitution. The book provides a comprehensive outlook on Botany Sciences, considering the history and traditional knowledge of plants, and relating it to contemporary problems and concerns of flora conservation today. With this current perspective, this book reaches a vast audience from the research lines of Botany, and encompasses a broader and interdisciplinary understanding of Aspects of Brazilian Floristic Diversity.
    Materialart: Online-Ressource
    Seiten: XXIV, 268 p. 49 illus., 42 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031074530
    URL: https://doi.org/10.1007/978-3-031-07453-0
    DOI: 10.1007/978-3-031-07453-0
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 56
    Online-Ressource
    Online-Ressource
    Cancer Metastasis Through the Lymphovascular System (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Metastasis. ; Lymphatics. ; Cancer Biology. ; Metastasis. ; Lymphatic System.
    Beschreibung / Inhaltsverzeichnis: Section 1: Genetic and Molecular Pathways of Cancer Growth and Metastasis -- Chapter 1. Hallmarks of Cancer: Molecular Underpinnings -- Chapter 2. Unifying concept of genomic changes: The mutational landscape of cancers -- Chapter 3. Tumor Microenvironment: Coconspirator in Tumorigenesis -- Chapter 4. Hallmarks of Metastasis: Molecular Underpinnings -- Chapter 5. Hereditary Cancer Syndromes and Cancer Metastasis -- Section 2: Pathology of Cancer Growth and Metastasis -- Chapter 6. Pathologic Assessment of Lymph Node Metastasis -- Chapter 7. Pathologic Assessment of Systemic or Distant Metastasis -- Chapter 8. The Role of Angiotropic Extravascular Migratory Metastasis in Metastases -- Section 3: Dormant Cancer Cells and their Reactivation in the Host Cancer Microenvironment -- Chapter 9. Tumor Dormancy and Relapse Regulated by the Extracellular Matrix -- Chapter 10. Therapy-Induced Dormancy and Residual Disease -- Section 4: The Microenvironment of Site-Specific Metastasis - Isaac P. Witz -- Chapter 11. The Microenvironment of Site-Specific Metastasis -- Section 5: Circulating Cancer Cells and Liquid Biopsy -- Chapter 12. Circulating tumor cells and ctDNA in sarcomas -- Chapter 13. Liquid biopsy using cell-free tumor DNA for gastrointestinal cancers -- Chapter 14. Circulating tumor cells and ctDNA in prostate cancer.-Chapter 15. Circulating Tumor Cells in Lung Cancer -- Chapter 16. CTCs/ ctDNA and Brain Metastasis.-Chapter 17. Epigenetics and liquid biopsy in oncology: role in metastasis and clinical utility -- Chapter 18. Metabolic reprogramming of circulating tumor cells for metastasis -- Section 6: Lymphatic System and Cancer Metastasis -- Chapter 19. Lymphatic System Biology, Pathobiology, and Relation to Cancer Metastasis -- Chapter 20. Lymphatic Specification and Development, EMT-MET, and Cancer Spread -- Chapter 21. Lymphangiogenesis, Lymph Nodes, Cancer Lymphangiogenesis and Metastasis -- Chapter 22. Immune cell trafficking in the lymphatics, hyaluronan biology and tumour metastasis -- Chapter 23. Lymphvascular Genomics and Proteomics, Clinical Syndromes, and Cancer Metastasis -- Chapter 24. Imaging of the Lymphatic System with Relevance to Cancer and Cancer Metastasis -- Chapter 25. Lymphedema: general pathophysiology, prevention and management in invasive cancer -- Section 7: Radiological Imaging of Early Cancer and Cancer Metastases -- Chapter 26. Primary Tumor Staging and Detection of Common Sites of Distant Metastatic Disease -- Chapter 27. Imaging Modalities in the Detection and Diagnosis of Metastatic Disease -- Chapter 28. Imaging of Bone Metastases -- Chapter 29. Imaging of Lung and Soft Tissue Metastases -- Chapter 30. Image-Guided Biopsy and Intervention for Metastatic Disease -- Section 8: Sentinel Lymph Node Surgery for Solid Cancer. Chapter 31. Sentinel Lymph Node Biopsy for Primary Cutaneous Malignancy -- Chapter 32. Sentinel Lymph Node Biopsy in Breast Cancer -- Chapter 33. Sentinel node navigation surgery for upper gastrointestinal cancer -- Chapter 34. Sentinel Lymph Node Mapping in Non-Small Cell Lung, Colon, and Thyroid Carcinomas -- Section 9: Surgical Treatment of Primary and Metastatic Cancer -- Chapter 35. The efficacy and evolution of surgical management based on cancer biology -- Chapter 36. The role of surgery in managing primary and metastatic melanoma -- Chapter 37. The Role of Surgery in Managing Primary and Metastatic Breast Cancer -- Chapter 38. The role of surgery in managing primary and metastatic colorectal cancer -- Chapter 39. The Role of Surgery in Management of Gastric Cancer -- Chapter 40. The role of surgery in managing primary and metastatic hepatopancreaticobiliary cancers -- Section 10: Cancer Metastasis to the Lung -- Chapter 41. Metastatic disease of the lung -- Section 11: Cancer Metastasis to the Liver -- Chapter 42. Tumor Resection and Ablation as a Means of Controlling Hepatic Metastases -- Chapter 43. Regional Arterial Infusional Therapy as a Means of Controlling Hepatic Metastases -- Section 12: Cancer Metastasis to the Bone -- Chapter 44. Molecular Mechanisms of Metastasis to the Bone.-Chapter 45. Surgical Management of Metastatic Disease to the Upper Extremity -- Chapter 46. Surgical Management of Metastatic Disease to the Lower Extremity -- Chapter 47. Surgical management of metastatic disease to the pelvis -- Chapter 48. Surgical Management of Metastatic Disease to the Spine -- Chapter 49. Interventional radiology techniques for management of skeletal metastases -- Section 13: Cancer Metastasis to the Brain and the Nervous System -- Chapter 50. Brain Metastases: Overview and Molecular Mechanisms -- Chapter 51. Indications and Techniques for Surgical Intervention in Patients with Metastatic Brain Tumors -- Chapter 52. Brain Metastases: Current and Future pharmacological treatment -- Chapter 53. Radiotherapy for CNS Metastases -- Chapter 54. Leptomeningeal Carcinomatoses -- Section 14: Urologic Cancer and 1st Patterns of Metastasis -- Chapter 55. Urologic Cancer and 1st Patterns of Metastasis -- Section 15: Biology and Clinical Aspects of Sarcoma Progression -- Chapter 56. Soft Tissue Sarcoma -- Chapter 57. Bone Sarcoma -- Chapter 58. Liposarcoma Metastasis -- Chapter 59. Desmoid Tumors.-Chapter 60. Atypical patterns of metastases: How do Sarcoma’s metastasize? -- Chapter 61. Tumor Immune Microenvironment of Soft Tissue Sarcoma -- Section 16: The Role of Radiation in the Treatment of Primary and Metastatic Cancer -- Chapter 62. Basic Principles of Radiobiology and Cancer Metastasis Prevention -- Chapter 63. Technical Innovations in the Delivery of Radiation Therapy -- Chapter 64. Radiation Therapy in the Definitive Treatment of Cancer -- Chapter 65. Radiation Therapy for Extracranial Oligometastatic Disease -- Chapter 66. Spine Radiotherapy -- Section 17: Immunotherapy of Solid Malignancies -- Chapter 67. Immunotherapy in Melanoma and Merkel Cell Cancer -- Chapter 68. Landscape of Immunotherapy in Lung Cancer -- Chapter 69. Immuno-oncologic Treatment of Genitourinary Malignancies -- Section 18: Current Topics -- Chapter 70. Personalized Systemic Cancer Therapy -- Chapter 71. Cancer Stem Cells and Their Role in Metastasis -- Chapter 72. HPV Induced Cancers -- Chapter 73. Microbiome and Cancer Metastasis -- Chapter 74. Application of Artificial Intelligence in Research on Cancer and Its Metastasis.
    Kurzfassung: This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. .
    Materialart: Online-Ressource
    Seiten: XXIV, 806 p. 145 illus., 106 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030930844
    URL: https://doi.org/10.1007/978-3-030-93084-4
    DOI: 10.1007/978-3-030-93084-4
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 57
    Online-Ressource
    Online-Ressource
    Root-Galling Disease of Vegetable Plants (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Plant physiology. ; Plant diseases. ; Plant Science. ; Plant Physiology. ; Plant Pathology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 -- Root-knot Nematodes (Meloidogyne spp.), Chapter 2 -- Meloidogyne species: Threat to Vegetable Produce, Chapter 3 -- hemotaxis in Root-Knot Nematodes, Chapter 4 -- Phytohormone-Mediated Feeding Site Development, Chapter 5 -- 5. Current and Future Studies on the Genes for Parasitism in Meloidogyne, Chapter 6 -- Natural Product Repertoire for Suppressing the Immune Response of Meloidogyne species, Chapter 7 -- Epigenetic Mechanisms and their Role in Root Gall Formation,Chapter 8 -- Mass Spectrometry Imaging (MSI) and Root Gall Elucidation, Chapter 9 -- 9. Root-Knot Disease Complex: An Interactive Perspective with Microorganisms, Chapter 10 -- Breeding for Resistance in Vegetables against Meloidogyne species causing Root Gall Disease, Chapter 11 -- An Overview of Predacious Fungi for the Management of Root-knot Disease in Vegetables, Chapter 12 -- Biofertilizer of Organic Origin for Management of Root Galling Disease of Vegetables, Chapter 13 -- Prospects for the Use of Metabolomics Engineering in Exploring and Harnessing Chemical Signalling in Root Galls.
    Kurzfassung: This book provides the most comprehensive and up-to-date review of research on vegetable plants associated with root-galls disease caused by root-knot nematodes (RKNs), Meloidogyne spp. Vegetables retain a key position in cultural cuisines and their consumption worldwide due to rich sources of micronutrients, including vitamins, minerals and antioxidants, but root galls disease of these crops caused by RKNs steals both quantity and quality from production. The field of plant nematology has experienced exponential growth over the past decade, and these RKNs are now known as widely damaging obligate plant parasites of vegetable plants. Advances are being made in understanding their biology, parasitism in the root system, giant cell development, root gall formation, chemical signalling, root-knot disease complexes, and management systems. This compilation provides an invaluable resource for studying root-galls disease of vegetable plants to those readers associated with plant nematology, plant pathology, plant protection, and agricultural science, including researchers, teachers, advanced undergraduates and graduate students, and even agricultural extension agents and farmers.
    Materialart: Online-Ressource
    Seiten: XIX, 338 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819938926
    URL: https://doi.org/10.1007/978-981-99-3892-6
    DOI: 10.1007/978-981-99-3892-6
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 58
    Online-Ressource
    Online-Ressource
    Genomic Designing for Abiotic Stress Resistant Cereal Crops (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Genomic Improvement of Rice for Drought, Aluminum, and Iron Toxicity Stress Tolerance -- Advances In Breeding For Abiotic Stress Tolerance in Wheat -- Resistance to Abiotic Stress: Theory and Applications in Maize Breeding -- Genetic Diversity for Barley Adaptation to Stressful Environments -- Advances in Genomic Designing for Abiotic Stress Tolerance in Sorghum -- Genomic Designing for Abiotic Stress Tolerance in Pearl Millet -- Genomic Designing for Abiotic Stress Tolerance in Foxtail millet -- Genomic-Assisted Breeding in Finger Millet.
    Kurzfassung: This book presents abiotic stresses that cause crop damage in the range of 6-20%. Understanding the interaction of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., is important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in cereal crops is imperative for addressing FPNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has facilitated precise information about the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The nine chapters each dedicated to a cereal crop in this volume are deliberate on different types of abiotic stresses and their effects on and interaction with crop plants; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; are brief on the classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; elucidate on the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different emerging genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Materialart: Online-Ressource
    Seiten: XXIV, 317 p. 24 illus., 22 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030758752
    URL: https://doi.org/10.1007/978-3-030-75875-2
    DOI: 10.1007/978-3-030-75875-2
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 59
    Online-Ressource
    Online-Ressource
    Mineral Biofortification in Crop Plants for Ensuring Food Security (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Human ecology Study and teaching. ; Plant Science. ; Environmental Studies.
    Beschreibung / Inhaltsverzeichnis: 1. Agronomic Biofortification- An Effective Tool for Alleviating Nutrient Deficiency in Plants and Human Diet -- 2. The Role of Biofortification in Enhancing Plant Growth, Development, Yield, and Quality -- 3. Improving Zinc Biofortification in Plants 4. Biofortification of Zinc: Uptake from the Soil and Transportation up to the Grains through ZIP Family Transporters -- 5. Mechanisms of Iron Uptake and Homeostasis in Plants: Implications for Biofortification in Cereal Grains -- 6. Selenium Biofortification in Agronomic Crops -- 7. Selenium Bio-fortification in Cereal Crops: An Overview -- 8. Nanoparticles Based Biofortification in Food Crops: Overview, Implications, and Prospects -- 9. Role of Nanoparticles in Improving Biofortification -- 10. Role of Nanoparticles in Improving Biofortification of Zinc and Iron in Vegetables -- 11. Scope of Seed Priming in Inducing Biofortification in Plants -- 12. Biofortification Through Seed Priming in Food Crops; Potential Benefits and Future Scope -- 13. Biochar for the Improvement of Crop Production -- 14. Phytohormones as Stress Mitigators in Plants.
    Kurzfassung: This book provides a comprehensive summary of the recent advances in the biofortification of plants under climate change and how it affects food security globally. The need for mineral biofortification to eradicate or alleviate malnutrition through sustainable agriculture is also discussed. Biofortification of edible plants is considered the most appropriate approach to alleviate nutritional problems and nutrient deficiencies. In contrast, biofortification focuses on improving the nutritional content of the region's current agricultural biodiversity while preserving its habits and customs. Emphasis is also placed on recent advances and developments in omics, particularly metabolomics and related techniques, to unravel the potential alterations in plants caused by biofortification. The book brings together eminent scientists to present the latest developments in the field. This timely publication addresses practical scenarios of bio-fortified food production and climate change. The book focuses on the methods, techniques, and environmental changes used to enhance and improve agricultural products. This book is one of the first to provide information on the use of modern biotechnologies to modify crops for health benefits. It also examines the mechanisms of the plant responses to genetically induced biofortification, the production and responses of fortified plants under climate change, and their effects on food security. The book will be useful for students and researchers, especially crop scientists, environmental scientists, biotechnologists, botanists, and agronomists, to understand the techniques and mechanisms of biofortification, and responses of biofortified plants under climate change.
    Materialart: Online-Ressource
    Seiten: XI, 338 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819940905
    URL: https://doi.org/10.1007/978-981-99-4090-5
    DOI: 10.1007/978-981-99-4090-5
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 60
    Online-Ressource
    Online-Ressource
    The Alfalfa Genome (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Economic Importance, Practical Limitations to Production, Management and Breeding Targets of Alfalfa -- Chapter 2. Factors Influencing Yield and Quality -- Chapter 3. The Origin, Evolution and Genetic Diversity of Alfalfa -- Chapter 4. Germplasm Collection, Genetic Resources and Gene Pools in Alfalfa -- Chapter 5. Biotechnology Advances in Alfalfa -- Chapter 6. Sequencing, Assembly and Annotation of the Alfalfa Genome -- Chapter 7. Transcription Factors in Alfalfa (Medicago sativa L.): Genome-Wide Identification and a Web Resource Center AlfalfaTFDB -- Chapter 8. Genomics of Forage Quality in Alfalfa -- Chapter 9. Physiological, Morphological, Biochemical, and Genetic Responses of Alfalfa to Salinity -- Chapter 10. Developing SNPs and Strategies for Genomic Analysis in Alfalfa -- Chapter 11. Genomics Resources for Breeding in Alfalfa: Availability, Utility, and Adoption -- Chapter 12. Genomic Selection for Higher Yield and Quality in Alfalfa -- Chapter 13. Identification and Characterization of Disease Resistance Genes in Alfalfa and Medicago truncatula for Breeding Improved Cultivars -- Chapter 14. Genetic and Genomic Assessments for Improving Drought Resilience in Alfalfa -- Chapter 15. Self-Incompatibility, Inbreeding Depression, and Potential to Develop Inbred Lines in Alfalfa -- Chapter 16. Targeted Mutagenesis of Alfalfa.
    Kurzfassung: This book is the first comprehensive compilation of deliberations on whole genome sequencing of the diploid and tetraploid alfalfa genomes including sequence assembly, gene annotation, and comparative genomics with the model legume genome, functional genomics, and genomics of important agronomic characters. Other chapters describe the genetic diversity and germplasm collections of alfalfa, as well as development of genetic markers and genome-wide association and genomic selection for economical important traits, genome editing, genomics, and breeding targets to address current and future needs. Altogether, the book contains about 300 pages over 16 chapters authored by globally reputed experts on the relevant field in this crop. This book is useful to the students, teachers, and scientists in the academia and relevant private companies interested in genetics, breeding, pathology, physiology, molecular genetics and breeding, biotechnology, and structural and functional genomics. The work is also useful to seed and forage industries.
    Materialart: Online-Ressource
    Seiten: XXV, 283 p. 64 illus., 52 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030744663
    Serie: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-74466-3
    DOI: 10.1007/978-3-030-74466-3
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 61
    Online-Ressource
    Online-Ressource
    Hepatobiliary Cancers: An Interdisciplinary Approach (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Cancer. ; Cancer Treatment. ; Tumors Immunological aspects. ; Immunotherapy. ; Cancer Genetic aspects. ; Stem cells. ; Cancer Biology. ; Cancer Therapy. ; Tumour Immunology. ; Immunotherapy. ; Cancer Genetics and Genomics. ; Cancer Stem Cells.
    Beschreibung / Inhaltsverzeichnis: Interdisciplinary Approach in Hepatobiliary Cancers -- Liver Cancer: Interdisciplinary Approach -- The Immune System in Liver Cancer: From Beginning to Progression -- The Tumor Microenvironment in Hepatocellular Carcinoma -- Metabolic Alterations of Hepatocellular Cancer Stem Cells -- Τhe Role of Senescence in NASH-related HCC -- Regulators of Genetic Risk for the Progression of Non-alcoholic Fatty Liver Disease to Hepatocellular Carcinoma: Reconstruction of Transcriptional Network and Signature-Based Metabolic Profiling -- Tumor Microenvironment and Immunotherapy in Advanced Biliary Tract Cancers -- Fibrosis and Immunotherapy in Hepatocellular Carcinoma -- Liver Cancer and the Curative Potential of Nanomedicine -- Locoregional Therapies for Hepatocellular Carcinoma -- Drug Resistance in Hepatocellular Carcinoma -- Liver Stereotactic Body Radiotherapy.
    Kurzfassung: Hepatobiliary cancers, including hepatocellular carcinoma and biliary tract cancers, have high rate of mortality and low survival rate. The third volume of the “Interdisciplinary Cancer Research” series, entitled “Hepatobiliary Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of hepatobiliary cancers and therapeutic modalities and presents the most updated and peer-reviewed chapters on hepatobiliary cancers. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on hepatobiliary cancers.
    Materialart: Online-Ressource
    Seiten: XI, 365 p. 22 illus., 21 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031445286
    Serie: Interdisciplinary Cancer Research, 3
    URL: https://doi.org/10.1007/978-3-031-44528-6
    DOI: 10.1007/978-3-031-44528-6
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 62
    Online-Ressource
    Online-Ressource
    Gastrointestinal Cancers: An Interdisciplinary Approach (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Cancer. ; Cancer Treatment. ; Oncology. ; Immunotherapy. ; Tumors Immunological aspects. ; Nanomedicine. ; Cancer Biology. ; Cancer Therapy. ; Oncology. ; Immunotherapy. ; Tumour Immunology. ; Cancer Nanotechnology.
    Beschreibung / Inhaltsverzeichnis: Interdisciplinary Approach in Gastrointestinal Cancers -- Gastrointestinal Cancers: What Is the Real Board of Microenvironment and the Role of Microbiota-Immunity Axis -- Epithelial-Mesenchymal Transition in Gastrointestinal Cancer: From a Basic to a Clinical Approach -- Metabolomics of Gastrointestinal Cancers -- Deregulation of Immune System in Gastric Cancer Development, How Immune Nutrition Might Restore the Functions of Immune Cells -- Helicobacter pylori Virulence Factors, Pathogenicity, and Gastric Cancer -- Gastric Cancer and Helicobacter pylori -- Role of Neuromodulators in Regulation of the Tumor Microenvironment of Gastric and Colorectal Cancers -- The Role of Tumor Microenvironment in Colon Cancer -- Unraveling the Esophageal Cancer Tumor Microenvironment: Insights and Novel Immunotherapeutic Strategies -- The Interplay Between Immunity and Gut Microbiota in Colon Cancer -- Immunotherapy in Gastrointestinal Cancer Focusing on CAR-T Cell Therapy -- Development of Biocompatible Nanocarriers for the Treatment of Colorectal Cancer -- Challenges of Onco-therapeutics in Early Onset Colorectal Cancer -- Unintentional Weight Loss and Malnutrition After Esophageal Cancer and Treatment -- Current Clinical Landscape of Immunotherapeutic Approaches in Pancreatic Cancer Treatment. The Tumor Microenvironment in Pancreatic Cancer and Challenges to Immunotherapy. .
    Kurzfassung: Gastrointestinal cancers are among the most prevalent malignancies worldwide, with high rate of global cancer incidence and cancer-related death. Gastrointestinal cancers include esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and liver cancer, which all, except the last one, are covered in this volume. The fourth volume of the “Interdisciplinary Cancer Research” series, entitled “Gastrointestinal Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of gastrointestinal cancers and novel immunotherapy opportunities and presents the most updated and peer-reviewed chapters on gastrointestinal cancers therapy. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on gastrointestinal cancers.
    Materialart: Online-Ressource
    Seiten: XI, 404 p. 22 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031483714
    Serie: Interdisciplinary Cancer Research, 4
    URL: https://doi.org/10.1007/978-3-031-48371-4
    DOI: 10.1007/978-3-031-48371-4
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 63
    Online-Ressource
    Online-Ressource
    Spores : Tulips with Fever, Rusty Coffee, Rotten Apples, Sad Oranges, Crazy Basil. Plant Diseases that Changed the World as Well as My Life (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Food Safety measures. ; Plant diseases. ; Agriculture. ; Environment. ; Public health. ; Plant Science. ; Food Safety. ; Plant Pathology. ; Agriculture. ; Environmental Sciences. ; Public Health.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Ancient Spores -- Spores of My Life -- Scary Spores -- Spores of the Future -- Conclusions.
    Kurzfassung: This book aims to describe, though in a quite light way, the social role of plant diseases, letting the reader know the topical importance of plant pathology, as well as the role of plant pathologists in our society. Plant diseases caused, in the past, significant economic losses, deaths, famine, wars, and migration. Some of them marked the history of entire countries. One example among many: the potato late blight in Ireland in 1845. Today plant diseases are still the cause of deaths, often silent, in developing countries, and relevant economic losses in the industrialized ones. This book, written with much passion, neither wants to be a plant pathology text. On the contrary, it wants to describe, in simple words, often enriched by the author's personal experience, various plant diseases that, in different times and countries, did cause severe losses and damages. Besides the so-called “historical plant diseases”, in the process of writing this book, she wanted to describe also some diseases that, though not causing famine or billions of losses, because of their peculiarity, might be of interest for the readers. Thus, this book has not been conceived and written for experts, but for a broader audience, of different ages, willing to learn more about plant health and to understand the reasons why so many people in the past and nowadays choose to be plant pathologists. This is because plants produce most of the food that we consume, that we expect healthy and safe, and because plants make the world beautiful. The title “Spores” is evocative of the reproduction mean of fungi. Spores are small, light structures, often moving fast. The chapters of this book are short and concise. Just like spores!
    Materialart: Online-Ressource
    Seiten: XXVI, 289 p. 174 illus., 166 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030699956
    URL: https://doi.org/10.1007/978-3-030-69995-6
    DOI: 10.1007/978-3-030-69995-6
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 64
    Online-Ressource
    Online-Ressource
    Mineral nutrition of tropical plants (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Plant physiology. ; Agriculture. ; Forestry. ; Plant Science. ; Plant Physiology. ; Agriculture. ; Forestry.
    Beschreibung / Inhaltsverzeichnis: Introduction to Plant Nutrition -- Ion Uptake by Roots -- Foliar Ion Uptake -- Nitrogen -- Sulphur -- Phosphorus -- Potassium -- Calcium -- Magnesium -- Boron -- Zinc -- Manganese -- Iron -- Copper -- Molybdenum -- Chlorine -- Nickel -- Potentially toxic metals -- Visual and Leaf Diagnosis -- Interactions between nutrients.
    Kurzfassung: This textbook aims to describe the role of minerals in plant life cycle; how these nutrients are absorbed, distributed, stored; what functions each mineral plays and the disorders that their excess or absence may cause. From an agronomic perspective, such knowledge is key to boost crop production and improve its quality, and it also helps understand how to better manage fertilizers and prevent environmental issues. The book has focus on tropical agriculture and its specific demands, providing examples of major crops (such as sugarcane, soybeans, coffee etc), silviculture and pasture species.
    Materialart: Online-Ressource
    Seiten: XVII, 339 p. 119 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030712624
    URL: https://doi.org/10.1007/978-3-030-71262-4
    DOI: 10.1007/978-3-030-71262-4
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 65
    Online-Ressource
    Online-Ressource
    Genomic Designing for Abiotic Stress Resistant Vegetable Crops (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Tomato -- Potato -- Capsicums -- Eggplant -- Vegetable Brassica -- Cucurbits -- Allums -- Amaranth.
    Kurzfassung: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in vegetable crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The nine chapters each dedicated to a vegetable crop or crop group in this volume elucidate on different types of abiotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops.
    Materialart: Online-Ressource
    Seiten: XXIII, 324 p. 16 illus., 13 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031039645
    URL: https://doi.org/10.1007/978-3-031-03964-5
    DOI: 10.1007/978-3-031-03964-5
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 66
    Online-Ressource
    Online-Ressource
    Translating Physiological Tools to Augment Crop Breeding (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Plant physiology. ; Agricultural genome mapping. ; Agriculture. ; Plant Science. ; Plant Physiology. ; Agricultural Genetics. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: 1. Importance of integrating physiological breeding to augment crop breeding -- 2. Stacking of complex traits through physiological pre breeding -- 3. Strategies to develop heat and drought tolerant wheat varieties following physiological breeding -- 4. Developing crop varieties by physiological breeding for improving plant nutrition -- 5. Role of Transpiration in Regulating Leaf Temperature and its Application in Physiological Breeding -- 6. Photosynthesis as a trait for improving yield potential in crops -- 7. Cuticular waxes and its application in crop improvement -- 8. Radiation use efficiency (RUE)-target for improving yield potential: Current status and future prospect -- 9. Application of Stable Isotopes in Crop Improvement -- 10. Root phenotyping for improved resource use efficiency in crops -- 11. Root system architecture and phenotyping for improved resource use efficiency in crops -- 12. Harnessing Root associated traits and Rhizosphere efficiency for Crop improvement -- 13. High throughput phenomics of crops for water and nitrogen stress -- 14. Metabolomics as a selection tool for abiotic stress tolerance in crops -- 15. Remote Sensing Algorithms and their Applications in Plant Phenotyping -- 16. Endophyte mediated crop improvement: Manipulation of abiotic stress‐specific traits -- 17. Impact of high temperature stress on selected food grain crops -- 18. Morpho-physiological basis of finger millet to withstand climatic extremes: A special reference to drought -- 19. Comprehending the physiological efficiency of millets under abiotic stress -- 20. Role of Next-generation sequencing in trait identification, genetic mapping, and crop improvement -- 21. Application of Artificial Intelligence and Machine Learning in Agriculture.
    Kurzfassung: This book covers different physiological processes, tools, and their application in crop breeding. Each chapter emphasizes on a specific trait/physiological process and its importance in crop, their phenotyping information and how best it can be employed for crop improvement by projecting on success stories in different crops. It covers wide range of physiological topics including advances in field phenotyping, role of endophytic fungi, metabolomics, application of stable isotopes, high throughput phenomics, transpiration efficiency, root phenotyping and root exudates for improved resource use efficiency, cuticular wax and its application, advances in photosynthetic studies, leaf spectral reflectance and physiological breeding in hardy crops like millets. This book also covers the futuristic research areas like artificial intelligence and machine learning. This contributed volume compiles all application parts of physiological tools along with their advanced research in these areas, which is very much need of the hour for both academics and researchers for ready reference. This book will be of interest to teachers, researchers, climate change scientists, capacity builders, and policy makers. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, physiology, botany, ecology, and environmental sciences. National and international agricultural scientists will also find this a useful resource.
    Materialart: Online-Ressource
    Seiten: XIV, 457 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811974984
    URL: https://doi.org/10.1007/978-981-19-7498-4
    DOI: 10.1007/978-981-19-7498-4
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 67
    Online-Ressource
    Online-Ressource
    Dietary Phytochemicals : A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Food science. ; Cancer Prevention. ; Nutrition   . ; Plant Science. ; Food Science. ; Cancer Prevention. ; Nutrition.
    Beschreibung / Inhaltsverzeichnis: 1. Etiology of obesity, cancer, and diabetes -- 2. Pathophysiology of Obesity and Diabetes -- 3. Pathophysiology of obesity and cancer: Drugs and signaling targets -- 4. Peptides Involved in body weight regulation -- 5. Insulin resistance- a link between obesity and cancer -- 6. Role of the cytoskeletal protein, actin in various diseases -- 7. Diabetes mellitus and its management with plant-based therapy -- 8. Fruits and vegetables as sources of functional phytochemicals for the management of obesity, diabetes, and cancer -- 9. Spices in diabetes, cancer and obesity treatment -- 10. MicroRNAs as Targets of Dietary Phytochemicals in Obesity and Cancer -- 11. Natural phenolic compounds as anti-obesityand anti-cardiovascular disease agent -- 12. Harnessing the Potential of Phytochemicals for Breast Cancer Treatment.
    Kurzfassung: This book presents comprehensive coverage on the importance of good nutrition in the treatment and management of obesity, cancer and diabetes. Naturally occurring bioactive compounds are ubiquitous in most dietary plants available to humans and provide opportunities for the management of diseases. The text provides information about the major causes of these diseases and their association with nutrition. The text also covers the role of dietary phytochemicals in drug development and their pathways. Later chapters emphasize novel bioactive compounds as anti-diabetic, anti-cancer and anti-obesity agents and describe their mechanisms to regulate cell metabolism. Written by global team of experts, Dietary Phytochemicals: A Source of Novel Bioactive Compounds for the Treatment of Obesity, Cancer and Diabetes describes the potentials of novel phytochemicals, their sources, and underlying mechanism of action. The chapters were drawn systematically and incorporated sequentially to facilitate proper understanding. This book is intended for nutritionists, physicians, medicinal chemists, drug developers in research and development, postgraduate students and scientists in area of nutrition and life sciences.
    Materialart: Online-Ressource
    Seiten: VIII, 265 p. 22 illus., 18 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030729998
    URL: https://doi.org/10.1007/978-3-030-72999-8
    DOI: 10.1007/978-3-030-72999-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 68
    Online-Ressource
    Online-Ressource
    Genomic Designing for Abiotic Stress Resistant Fruit Crops (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Genomics of Abiotic Stress Resistance in Malus domestica -- Genomic Designing for Abiotic Stress Resistant Banana -- Genetic Improvement of Citrus Limon (L. Burm f.) for Resistance to Mal Secco Disease -- Genomic Designing for Abiotic Stress Resistant Grapevine -- Wild and Related Species as a Breeding Source for Abiotic Stress Resistance of Peach Cultivars and Rootstocks -- Genomic Designing of new Almond-Peach Rootstock-variety Combinations Resistance to Plum pox virus -- Genomic Designing of New Plum Pox Virus Resistant Plumcot -- Integrated Genomic Designing and Insights for Disease Resistance and Crop Protection against Pathogens in Cherry -- Development of Abiotic Stress Tolerant Berries.
    Kurzfassung: This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in fruit crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing in many of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The seven chapters each dedicated to a fruit crop and a fruit crop group in this volume elucidate different types of abiotic stresses and their effects on and interaction with the crops; enumerate the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops. .
    Materialart: Online-Ressource
    Seiten: XXII, 249 p. 16 illus., 15 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031098758
    URL: https://doi.org/10.1007/978-3-031-09875-8
    DOI: 10.1007/978-3-031-09875-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 69
    Online-Ressource
    Online-Ressource
    Tumor Microenvironment : State of the Science (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Biomechanics. ; Cancer Biology. ; Biomechanics.
    Beschreibung / Inhaltsverzeichnis: Metabolism in the tumor microenvironment -- Neutrophil Elastase and Neutrophil Extracellular Traps in the Tumor Microenvironment -- Viral hepatitis, inflammation, and tumour microenvironment -- Effects of HIV on the tumor microenvironment -- GLI2-mediated inflammation in the tumor microenvironment -- Stellate Cells in the Tumor Microenvironment -- Endothelial Progenitors in the Tumor microenvironment -- Chimeric antigen receptors for the tumour microenvironment -- Toll-Like Receptors (TLRs) in the Tumor Microenvironment (TME): A dragon-Like Weapon in a Non-Fantasy Game of Thrones -- Multiple dynamics in tumor microenvironment under radiotherapy -- Index.
    Kurzfassung: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research in the field. A variety of topics are covered, including metabolism in the tumor microenvironment, stellate cells and endothelial progenitors in the tumor microenvironment, as well as the effects of HIV, viral hepatitis, and inflammation in the tumor microenvironment, and more. Taken alongside its companion volumes, Tumor Microenvironment: State of the Science updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Materialart: Online-Ressource
    Seiten: XIII, 208 p. 28 illus., 26 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030445188
    Serie: Advances in Experimental Medicine and Biology, 1263
    URL: https://doi.org/10.1007/978-3-030-44518-8
    DOI: 10.1007/978-3-030-44518-8
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 70
    Online-Ressource
    Online-Ressource
    Tumor Microenvironment : Recent Advances (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Stem cells. ; Regenerative medicine. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering.
    Beschreibung / Inhaltsverzeichnis: Novel techniques to study the bone-tumor microenvironment -- An emerging model for cancer development from a tumor -- microenvironment perspective in mice and humans -- Effects of Exercise on the Tumour Microenvironment -- Effects of inhaled tobacco smoke on the pulmonary tumor microenvironment -- Multimodal molecular imaging of the tumour microenvironment -- Necrosis in the tumor microenvironment and its role in cancer recurrence -- The Multifaceted Effects of Autophagy on the Tumor Microenvironment -- The Sociobiology of Brain Tumors -- Tumor microenvironment conditioning by abortive lytic replication of oncogenic γ-herpesviruses -- The microbiome as a component of the tumor microenvironment -- Index.
    Kurzfassung: This volume discusses recent research advances in cancer biology, focusing on the role of the tumor microenvironment. Taken alongside its companion volumes, Tumor Microenvironment: Recent Advances covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.
    Materialart: Online-Ressource
    Seiten: XI, 160 p. 31 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030357276
    Serie: Advances in Experimental Medicine and Biology, 1225
    URL: https://doi.org/10.1007/978-3-030-35727-6
    DOI: 10.1007/978-3-030-35727-6
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 71
    Online-Ressource
    Online-Ressource
    Tumor Microenvironment : Non-Hematopoietic Cells (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Stem cells. ; Regenerative medicine. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering.
    Beschreibung / Inhaltsverzeichnis: Adipocytes in the tumour microenvironment -- Fibroblasts in the tumor microenvironment -- Mesenchymal stem cells in the tumor microenvironment -- Hepatic stellate cells in liver tumor -- Pancreatic stellate cells: The key orchestrator of the pancreatic tumor microenvironment -- Endothelial cells in the tumor microenvironment -- Lymphatic endothelial cell progenitors in the tumor microenvironment -- Oligodendrocyte progenitors in the tumor microenvironment -- Index.
    Kurzfassung: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on non-hematopoietic cells within the tumor microenvironment.Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include fibroblasts, adipocytes, mesenchymal stem cells, stellate cells, and more. Taken alongside its companion volumes, Tumor Microenvironment: Non-Hematopoietic Cells updates us on what we know about the different aspects of the tumor microenvironment as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists focused in the tumor microenvironment and how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment. All of the chapter authors are renowned international experts in the cancer biology field in specific subfields that will be the focus of their chapters.
    Materialart: Online-Ressource
    Seiten: X, 129 p. 31 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030371845
    Serie: Advances in Experimental Medicine and Biology, 1234
    URL: https://doi.org/10.1007/978-3-030-37184-5
    DOI: 10.1007/978-3-030-37184-5
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 72
    Online-Ressource
    Online-Ressource
    Phytoremediation : In-situ Applications (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Pollution. ; Botanical chemistry. ; Plant Science. ; Agriculture. ; Pollution. ; Plant Biochemistry.
    Beschreibung / Inhaltsverzeichnis: In-Situ Phytoremediation of Metals -- Phytoremediation of Organic Pollutants -- Phytoremediation of Agricultural Pollutants -- Prinicples of Phytoremediation -- Rhizobacteria enhance root exudation, metal uptake and plant growth under abiotic stress -- Exploiting the Rhizosphere for Phytoremediation Enhancement -- Phytoremiediation of metals by aquatic macrophytes -- Phytoremediation using crop plants -- Phytoremediation using algae -- Impact of munitions compounds on native vegetation -- Phytoremediation of soils contaminated by hydrocarbon -- Exploitation of Rhizosphere for Phytoenhancement of HM Contaminated Industrial Soils using MYCORRHIZOREMEDIATION Technology -- Phytoremediation using Native Plants -- Phytoremediation using Aquatic Plants -- Growing Role of Biotechnology in Phytoremediation -- History of Phytoremediation -- Exploiting the Rhizosphere for Phytoremediation Enhancement -- Phytoremediation of wastewater -- Rhizosphere for Phytoremediation Enhancement.
    Kurzfassung: This book provides in-situ phytoremediation strategies that are particularly well suited for developing nations. Its goal is to promote the use of field-tested phytoremediation methods for removing soil and water pollutants from agricultural, industrial, military, and municipal sources. These strategies include using algae and a variety of aquatic and terrestrial plants. The book subsequently discusses the use of crops and native plants for phytoremediation, and how phytoremediation efforts impact the rhizosphere. After having finished the book, readers will be able to directly adapt the strategies described here for their specific purposes. .
    Materialart: Online-Ressource
    Seiten: VIII, 367 p. 38 illus., 28 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030000998
    Serie: Concepts and Strategies in Plant Sciences,
    URL: https://doi.org/10.1007/978-3-030-00099-8
    DOI: 10.1007/978-3-030-00099-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 73
    Online-Ressource
    Online-Ressource
    'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Oncology. ; Medical genetics. ; Bioinformatics. ; Microtechnology. ; Microelectromechanical systems. ; Cancer Biology. ; Oncology. ; Medical Genetics. ; Bioinformatics. ; Microsystems and MEMS.
    Beschreibung / Inhaltsverzeichnis: Module 1_ Introduction -- Module 2_ Cancer Metastasis -- Module 3_ Role of Transcriptomics in cancer treatment strategies -- Module 4_Computational approaches -- Module 5_Biostatistics and clinical oncology -- Module 6_Pharmacogenomics in cancer -- Chapter 7_Case studies.
    Kurzfassung: This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.
    Materialart: Online-Ressource
    Seiten: XVIII, 499 p. 59 illus., 50 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811510670
    URL: https://doi.org/10.1007/978-981-15-1067-0
    DOI: 10.1007/978-981-15-1067-0
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 74
    Online-Ressource
    Online-Ressource
    Diseases of the Breast during Pregnancy and Lactation (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Human physiology. ; Medicine Research. ; Biology Research. ; Gynecology . ; Cancer Biology. ; Human Physiology. ; Biomedical Research. ; Gynecology.
    Beschreibung / Inhaltsverzeichnis: Preface -- PART 1: Basic Considerations -- Anatomy and Physiology of the Breast during Pregnancy and Lactation -- Diagnosis of Breast Disorders in Pregnancy and Lactation -- Clinical Presentations of Breast Disorders in Pregnancy and Lactation -- PART 2: Benign and Premalignant Disorders of the Breast in Pregnancy and Lactation -- Benign Disorders of the Breast in Pregnancy and Lactation -- Mastitis, Breast Abscess, and Granulomatous -- Premalignant disorders of the Breast in Pregnancy and Lactation -- PART 3: Breast Cancer in Pregnancy and Lactation -- Epidemiology of Pregnancy-Associated Breast Cancer -- Histology of Pregnancy-Associated Breast Cancer -- Clinical presentation, Diagnosis, and Prognosis of Pregnancy-Associated Breast Cancer -- . Treatment of Pregnancy-Associated Breast Cancer -- Special Clinical Situations -- Prenatal Care during and after Breast Cancer Treatment -- Lactation during and after Breast Cancer -- Pregnancy in Breast Cancer Survivors. Impact of Breast Cancer Treatment on Fertility -- Fertility Counseling and Preservation for Breast Cancer Patients -- Pregnancy after Breast Reconstruction -- Pregnancy and Lactation: Risk or Protective Factors for Breast Cancer -- Psychological Aspects of Pregnancy and Lactation in Patients with Breast Cancer.
    Kurzfassung: Symptoms of the breast in gravid women commonly represent physiological changes, however they may also be related to serious underlying breast disease; this challenging dilemma is aggravated by diagnostic and therapeutic limitations imposed by safety issues regarding the mother and fetus. A comprehensive coverage of all aspects of normal and pathologic breast changes during pregnancy and lactation, their diagnosis and management is provided in the present work. The organized structure of this book begins with gestational changes of the breast, while discussing safety, hazards, and arguments regarding diagnostic approaches. It then goes on by describing various clinical presentations and common and uncommon benign disorders during gravidity. The book then addresses pre-malignant lesions of the breast, opening the dialogue on how to manage these confusing lesions in pregnant and nursing women. It continues toward pregnancy-associated breast cancer, focusing on every facet of the problem, including epidemiology, diagnosis, treatment and complications, anesthetic considerations, prenatal care, and rare malignancies; and comes to an end by arguing main psychological concerns. In the midst of this orderly sequence fertility issues, pregnancy, and breastfeeding in women who have overcome their breast cancer are also discussed. This unique reference has been written by academic experts from different centers and diverse disciplines in a practical format. It is intended to be an ideal resource for every practitioner and specialist who manages complaints of gravid and nursing women or treats breast disorders in women of child bearing age.
    Materialart: Online-Ressource
    Seiten: XXV, 216 p. 55 illus., 38 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030415969
    Serie: Advances in Experimental Medicine and Biology, 1252
    URL: https://doi.org/10.1007/978-3-030-41596-9
    DOI: 10.1007/978-3-030-41596-9
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 75
    Online-Ressource
    Online-Ressource
    The Teak Genome (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Teak: The King of Timbers -- Chapter 2. Teak Plantations and Wood Production -- Chapter 3. Modern Silvicultural Practices and Productivity of Teak -- Chapter 4. Analysis and Modeling of Teak growth: New Perspectives for Productivity Evaluation -- Chapter 5. Economics of Teak -- Chapter 6. Teak Biology and Ecology -- Chapter 7. Teak Wood Chemistry and Natural Durability -- Chapter 8. Wood Properties and their Variations in Teak -- Chapter 9. Seed Biology and Seed Orchard Dynamics in Teak -- Chapter 10. Clonal Teak -- Chapter 11. Clonal Characterization and Variety Registration of Teak -- Chapter 12. Genetic Diversity and Population Genetic Structure of Teak -- Chapter 13. Genetic Improvement of Teak -- Chapter 14. Molecular Physiology of Teak -- Chapter 15. Genome of Teak: Structure and Features -- Chapter 16. Functional Genomics of Teak. .
    Kurzfassung: This book is the first comprehensive compilation of knowledge on teak biology, ecology, clonal forestry, clonal registration, seed biology, and seed orchards. The teak genetic diversity, the sequenced genome, and transcriptomes from different tissues and their implications in modern tree improvement and material selection have been comprehensively discussed. The book also presents a narrative on wood characterization, wood chemistry, modern silviculture, growth and modelling, and economics of this valued tropical species. Altogether, the book contains about 200 pages over 16 chapters authored by globally reputed experts on the relevant field in this tropical tree. This book is useful to students, teachers, and scientists, and wood-based industries are interested in forestry, biology, seed orchards, breeding, genetic diversity, molecular genetics, in vitro culture, wood chemistry, and structural and functional genomics.
    Materialart: Online-Ressource
    Seiten: XXV, 265 p. 48 illus., 40 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030793111
    Serie: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-030-79311-1
    DOI: 10.1007/978-3-030-79311-1
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 76
    Online-Ressource
    Online-Ressource
    Underutilised Crop Genomes (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. The Broomcorn Millet Genome -- Chapter 2. Buckwheat Genome and Genomics -- Chapter 3. Tef [Eragrostistis tef (Zucc.) Trotter] -- Chapter 4. The Apricot Genome -- Chapter 5. Chinese Jujube: Crop Background and Genome Sequencing -- Chapter 6. The Longan (Dimocarpus longan) Genome -- Chapter 7. The Mangosteen Genome -- Chapter 8. The Passion Fruit Genome -- Chapter 9. The Soursop Genome (Annona muricata L., Annonaceae) -- Chapter 10. Underutilised Fruit Tree Genomes from Indonesia -- Chapter 11. The Bambara Groundnut Genome: From the Crop to the Genome -- Chapter 12. Grasspea -- Chapter 13. The Lablab Genome -- Chapter 14. The Perennial Horse Gram (Macrotyloma axillare) Genome, Phylogeny, and Selection Across the Fabaceae -- Chapter 15. Breeding and Genomics of Pigeonpea in the Post-NGS Era -- Chapter 16. Rice Bean -- Chapter 17. The Winged Bean Genome: One Species Supermarket -- Chapter 18. Castor Bean: Recent Progress in Understanding the Genome of this Underutilized Crop -- Chapter 19. Genome Resources for Ensete Ventricosum (enset) and Related Species -- Chapter 20. Yam Genomics -- Chapter 21. The African Eggplant -- Chapter 22. Sequencing of the Bottle Gourd Genomes Enhances Understanding of the Ancient Orphan Crop -- Chapter 23. Advances and Prospects in Genomic and Functional Studies of the Aquatic Crop, Sacred Lotus -- Chapter 24. Utilising Public Resources for Fundamental Work in Underutilised and Orphan Crops.
    Kurzfassung: This book highlights the uses for underutilized crops, presenting the state-of-the-art in terms of genome sequencing for over 30 crops, previously understudied and under-researched. In a changing climate and with significant pressure on the land, it is the ideal time to be discussing novel crops, with significant biotic and abiotic tolerances and/or rich nutrient profiles for consumers. Previously, the only species with sequenced genomes were high-profile internationally recognized crops, but in the current era genomes are being sequenced for dozens of crops, including those previously classified as underutilized, now being investigated. This book covers food crops, from fruits to tubers, and from grasses to legumes, as well as crops with non-food applications. Some of these crops have draft genomes, and others have polished genomes with extensive resequencing panels. Each chapter tells the story of an individual crop or crop group, written by experts, focusing on the genome data available, revealing more about crop domestication and genetic variation, and the current and future prospects given that this data is now becoming available. It also highlights how even small sequencing projects can provide draft genome sequences suitable for gene discovery, comparative genomics, and identification of molecular markers for understanding these crops further.
    Materialart: Online-Ressource
    Seiten: XXIV, 450 p. 125 illus., 105 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031008481
    Serie: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-031-00848-1
    DOI: 10.1007/978-3-031-00848-1
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 77
    Online-Ressource
    Online-Ressource
    Systems Biology of MicroRNAs in Cancer (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Tumor markers. ; Non-coding RNA. ; Cancers. ; Tumour Biomarkers. ; Non-coding RNAs.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. The Role of MicroRNAs in Cancer Biology and Therapy from a Systems Biology Perspective -- Chapter 2. Circulating MicroRNAs as Cancer Biomarkers in Liquid Biopsies -- Chapter 3. Regulation of Immune Cells by MicroRNAs and MicroRNA-Based Cancer Immunotherapy -- Chapter 4. Machine-Learning-Based Methods and Best Practices of MicroRNA-Target Prediction and Validation -- Chapter 5. Turning Data to Knowledge: Online Tools, Databases and Resources in MicroRNA Research -- Chapter 6. Bioinformatics Methods for Modeling MicroRNA Regulatory Networks in Cancer -- Chapter 7. Analysis of the p53/MicroRNA Network in Cancer -- Chapter 8. Machine Learning Using Gene-Sets to Infer miRNA Function -- Chapter 9. miRNA:miRNA Interactions: A Novel Mode of miRNA Regulation and Its Effect on Disease -- Chapter 10. ClustMMRA v2: A Scalable Computational Pipeline for the Identification of MicroRNA Clusters Acting Cooperatively on Tumor Molecular Subgroups -- Chapter 11. 3D Modeling of Non-coding RNA Interactions.
    Kurzfassung: This book provides an update on the latest development in the field of microRNAs in cancer research with an emphasis on translational research. Since the early 2000s, microRNAs have been recognized as important and ubiquitous regulators of gene expression. Soon it became evident that their deregulation can cause human diseases including cancer. This book focuses on the emerging opportunities for the application of microRNA research in clinical practice. In this context, computer models are presented that can help to identify novel biomarkers, e.g. in circulating microRNAs, and tools that can help to design microRNA-based therapeutic interventions. Other chapters evaluate the role of microRNAs in immunotherapy, immune responses and drug resistance. Covering key topics on microRNAs in cancer research this book is a valuable resource for both emerging and established microRNA researchers who want to explore the potential of microRNAs as therapeutic targets or co-adjuvants in cancer therapies.
    Materialart: Online-Ressource
    Seiten: VII, 317 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031083563
    Serie: Advances in Experimental Medicine and Biology, 1385
    URL: https://doi.org/10.1007/978-3-031-08356-3
    DOI: 10.1007/978-3-031-08356-3
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 78
    Online-Ressource
    Online-Ressource
    The Seabuckthorn Genome (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Biosystematics and Botanical Descriptions of Seabuckthorn (Hippophae Sp.) in India -- Genetic Diversity, Evolution and Biogeography of Seabuckthorn -- Current Status of Chromosome-based Gender Determination in Seabuckthorn -- Analytical Techniques for the Biochemical Profiling in Seabuckthorn -- Effect of Processing and Storage on Seabuckthorn Products -- Metabolomic Diversity of Seabuckthorn Collections from Different Geographical Regions -- Deciphering the Proteomes and Nanotechnological Potential of an Unexplored Plant Seabuckthorn -- Biotechnological Approaches for Seabuckthorn Improvement -- Repertoire of Molecular Markers and their Applications in Seabuckthorn -- Barcoding-based Identification of Hippophae species -- Transcriptome Sequencing and Analysis of Seabuckthorn (Hippophae Sp.) -- Mining of Microsatellites and Transcription Factors in Seabuckthorn (Hippophae Sp.) Transcriptomes -- Frankia – The Endo-micro-symbiont of Hippophae Sp -- Medicinal and Nutraceutical Properties of Seabuckthorn -- Molecular and Cellular Mechanisms of the Anti-oxidative Activity of Seabuckthorn (Hippophae rhamnoides L.) -- Knowing More About Seabuckthorn (Hippophae rhamnoides)- A Promising Source of Safe and Effective Medical Radiation Countermeasure -- Methods in Seabuckthorn Breeding -- Global Distribution of Seabuckthorn (Hippophae Sp.) Resources and their Utilization .
    Kurzfassung: This work is the first compilation of comprehensive deliberations on botany, cytogenetics and sex determination, genetic resources and diversity, classical breeding, molecular markers and genome sequence resources, and application of omics technology including transcriptomics, proteomics, and metabolomics resources in the multipurpose medicinal plant seabuckthorn. The book also presents a detailed narrative on antioxidative, radioprotective nutraceutical, and medicinal applications of seabuckthorn products. A detailed treatment has been included on analytical techniques and processing technologies. Altogether, the book contains about 300 pages over 17 chapters contributed by globally reputed experts on the relevant field in this important plant species. This book will be useful to the research students, teachers, and scientists in the academia and private sector engaged in horticulture, genetics, breeding, molecular biology, biotechnology, and breeding. The book will also be a useful source for workers involved in the development of plant-based medicines, nutraceuticals, therapeutics, and cosmeceuticals and extension workers involved in the development of rural farmers and small-scale industries.
    Materialart: Online-Ressource
    Seiten: XXIX, 368 p. 74 illus., 63 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031112768
    Serie: Compendium of Plant Genomes,
    URL: https://doi.org/10.1007/978-3-031-11276-8
    DOI: 10.1007/978-3-031-11276-8
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 79
    Online-Ressource
    Online-Ressource
    Tumor Microenvironment : Extracellular Matrix Components – Part B (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Stem cells. ; Regenerative medicine. ; Cytology. ; Cancer Microenvironment. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Elastin in the Tumor Microenvironment -- Decorin in the tumor microenvironment -- Syndecan-1 in the tumor microenvironment -- Versican in the tumor microenvironment -- Chondroitin Sulphate Proteoglycans in the Tumour Microenvironment -- Lipoproteins and the Tumor Microenvironment -- The Role of BEHAB/Brevican in the Tumor Microenvironment: Mediating Glioma Cell Invasion and Motility -- Thrombospondin in Tumor Microenvironment -- Tenascin-C function in glioma: immunomodulation and beyond -- Index.
    Kurzfassung: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components of the tumor microenvironment during cancer development. Furthermore, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include elastin, decorin, syndecan-1, versican, lipoproteins, brevican, thrombospondin, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part B updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newest generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book is an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapters authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.
    Materialart: Online-Ressource
    Seiten: XIII, 178 p. 36 illus., 33 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030484576
    Serie: Advances in Experimental Medicine and Biology, 1272
    URL: https://doi.org/10.1007/978-3-030-48457-6
    DOI: 10.1007/978-3-030-48457-6
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 80
    Online-Ressource
    Online-Ressource
    Phytochemical Genomics : Plant Metabolomics and Medicinal Plant Genomics (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Genetics. ; Biology Technique. ; Biology. ; Molecular biology. ; Biochemistry. ; Plant Science. ; Genetics and Genomics. ; Biological Techniques. ; Biological Sciences. ; Molecular Biology. ; Chemical Biology.
    Beschreibung / Inhaltsverzeichnis: 1.Phytochemical genomics: integration of omics approaches for understanding genomic basis of phytochemicals -- 2.Gene-metabolite networks -- 3.Computational approaches in phytochemical genomics -- 4.Databases relevant to phytochemicals and genes responsible -- 5.Biosynthetic pathways of important metabolites using genomics and metabolomics approaches -- 6.Phytochemical diversity and the diverse roles of phytochemicals in plants -- 7.Role of genomics and metabolomics for breeding crops with higher quantity of metabolites -- 8.Metabolic quantitative trait loci mapping of medicinal plants and crops -- 9.Tools for metabolomics analysis of plants -- 10.Trichomes as an important chemical factories of metabolites -- 11.Stress and metabolites -- 12.Evolution of metabolite diversity and defense mechanisms in plants -- 13.Pathway engineering of genes -- 14.Demand-supply of phytochemicals and the need for ensuring sustainable supply of plants -- 15.Drug discovery and omics -- 16.Gene editing technologies for scaling up production of secondary metabolites -- 17.Medicinal plants and use of omics approaches -- 18.Metabolomics of important medicinal plants -- 19.Transcriptomics of important medicinal plants.
    Kurzfassung: This book provides a comprehensive reference for various plant bioactive compounds for research and pharmacological significance across the entire spectrum of phytochemical genomics. The book opens with general information on diversity, analysis and genomic basis of phytochemicals, computational approaches, databases for responsible genes, and biosynthetic pathways, and it delves very much into the details behind phytochemical diversity and diverse roles of plant metabolites. The later parts of the book also explore the direct drug discovery and omics approaches including metabolomics, transcriptomics, as well as gene editing technology experiments to further inspire readers into its unlimited potentials. Each chapter includes detailed analysis and relevant experiments for better and deeper understanding of the concepts. The book will be an invaluable aid for medicinal plant researchers and a rich source of information and advice for advanced undergraduates and graduates in the fields of medicine, nutraceuticals, cosmetics, flavor, and fragrance studies.
    Materialart: Online-Ressource
    Seiten: XVIII, 698 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811957796
    URL: https://doi.org/10.1007/978-981-19-5779-6
    DOI: 10.1007/978-981-19-5779-6
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 81
    Online-Ressource
    Online-Ressource
    Immunotherapy (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Immunology. ; Oncology. ; Cancer Biology. ; Immunology. ; Oncology.
    Beschreibung / Inhaltsverzeichnis: Overview of Basic Immunology and Clinical Application -- Advances in Diagnostic Procedures and their Applications in the era of Cancer Immunotherapy -- Immunotherapy for Melanoma -- Immunotherapy in Lung Cancer: From a minor God to the Olympus -- Immunotherapy in Gastrointestinal Malignancies -- Current Landscape of Immunotherapy in Genitourinary Malignancies -- Immuno-oncology for Gynecologic Malignancies -- Immunotherapy for Neuro-Oncology -- Immunotherapy and Radiation -- CAR T-cells -- Skin Reactions to Immune Checkpoint Inhibitors -- Gastrointestinal Tract Adverse Events -- Immune-Related Adverse Events: Pneumonitis -- Hepatobiliary Adverse Events -- Immune Checkpoint Inhibitors (ICIs) Related Cardiotoxicity -- Renal Toxicity -- Immune-Related Oral, Otologic and Ocular Adverse Events -- Cancer Imaging in Immunotherapy -- The Microbiome in Immuno-Oncology -- New developments in the use of Patient-reported outcomes in Cancer Patients undergoing Immunotherapies.
    Kurzfassung: Immunotherapy is a rapidly evolving field that mandates frequent revision of the book as new insights to fight cancer emerge. The third edition of Immunotherapy is an updated overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. It explores the breath of immunotherapeutic strategies available to treat a wide range of cancers, from melanoma and non-small cell lung cancer to gastrointestinal, genitourinary, gynecologic and nervous system malignancies. With increasing use of checkpoint inhibitors as standard of care and in clinical trials, the challenges associated with their use undoubtedly increase. As objective response is limited to a subset of patients and is often associated with distinct immune related side effects that are potentially life threatening, it is essential to identify patients who are likely to respond to immunotherapy and those who are at a risk for developing treatment-related side effects. In the absence of a validated predictive biomarker, innovative technologies and assays are being used to identify critical biomarkers that drive the immune response. Hence, a chapter to provide a basic understanding of the diagnostic procedures has been included besides the chapter on the cellular components of the human immune system. This new edition will also inform readers on use of novel microbiome and imaging approaches. Finally, the book includes a chapter on patient-reported outcomes in patients treated with immunotherapies as the authors recognize the importance of including missing patient voice in clinical trials and longitudinal assessment of symptom reports. In short, the third edition of this book provides a comprehensive overview of the latest developments in the field of immune-oncology that will help health care professionals make informed treatment decisions. The book’s chapters are written by a diverse cast of experts conducting cutting-edge research, providing the reader with the most up-to-date science.
    Materialart: Online-Ressource
    Seiten: XII, 339 p. 44 illus., 35 illus. in color. , online resource.
    Ausgabe: 3rd ed. 2020.
    ISBN: 9783030410087
    Serie: Advances in Experimental Medicine and Biology, 1244
    URL: https://doi.org/10.1007/978-3-030-41008-7
    DOI: 10.1007/978-3-030-41008-7
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 82
    Online-Ressource
    Online-Ressource
    Circulating Tumor Cells in Breast Cancer Metastatic Disease (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Stem cells. ; Cancer Biology. ; Biomedical Research. ; Biotechnology. ; Stem Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Preface -- Introduction – Biology of Breast Cancer Metastasis and Importance of the Analysis of CTCs -- Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis -- Disseminated Tumor Cells and Dormancy in Breast Cancer Progression -- Methodology for the Isolation and Analysis of CTCs -- Advances in the Characterization of Circulating Tumor Cells in Metastatic Breast Cancer: Single Cell Analyses and Interactions, and Patient-derived Models for Drug Testing -- Circulating Tumor Cells (CTCs) Heterogeneity in Metastatic Breast Cancer: Different Approaches for Different Needs -- Relevance of CTC Clusters in Breast Cancer Metastasis -- Epigenetics of Circulating Tumor Cells in Breast Cancer -- Circulating Tumor Cells: Applications for Early Breast Cancer -- Clinical Relevance and Therapeutic Application of CTCs in Advanced Breast Cancer. .
    Kurzfassung: This book compiles the latest research and key findings about the role of circulating tumor cells (CTCs) in Breast Cancer progression, both from the research and clinical standpoint. Based on latest advancements, the content of the book is set out to provide a clear overview about the biology and use of CTCs as a tool for the monitoring and management of breast cancer patients. This work covers basic concepts about the process of metastasis, the biology of CTCs and their potential applications as a biomarker in breast cancer. It will enable readers to delve into the process of epithelial-mesenchymal plasticity (EMP), mechanisms and clinical implications of tumor cell dormancy and minimal residual disease, and into the phenotypical and molecular heterogeneity of CTCs and CTC clusters, including the epigenetic characterization of CTCs. Readers will find out about the key technologies used for the isolation of CTCs as well as the latest advances towards the characterization of CTCs, involving single cell analyses and patient-derived models. It will discuss the evidences about the use of CTCs as a tool to monitor breast cancer progression and therapy response, as well as to unravel mechanisms of resistance to therapy and to identify new therapeutic targets favoring the development of novel anticancer drugs. Lastly, it will discuss ongoing clinical trials and try to foresee the future of CTCs in terms of clinical application and implementation in the clinical routine. The topic of this book is particularly relevant for cancer researchers and oncologist with an interest in the field, looking to refresh or to broaden their knowledge and understanding about the use of CTCs as a diagnostic biomarker in breast cancer.
    Materialart: Online-Ressource
    Seiten: XV, 167 p. 15 illus., 14 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030358051
    Serie: Advances in Experimental Medicine and Biology, 1220
    URL: https://doi.org/10.1007/978-3-030-35805-1
    DOI: 10.1007/978-3-030-35805-1
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 83
    Online-Ressource
    Online-Ressource
    Artificial Intelligence and Precision Oncology : Bridging Cancer Research and Clinical Decision Support (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Cancer. ; Oncology. ; Medical screening. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Oncology. ; Cancer Screening. ; Cancer Therapy. ; Tumour Biomarkers.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction: The Application of AI in Precision Oncology: Tailoring Diagnosis, Treatment, and the Monitoring of Disease Progression to the Patient -- Part I. Artificial Intelligence for Screening, Diagnosis, Monitoring in Precision Oncology -- Chapter 2. Application of AI in Novel Biomarkers Detection that Induce Drug Resistance, Enhance Treatment Regimens and Advancing Precision Oncology -- Chapter 3. Use of Artificial Intelligence in Implementing Mainstream Precision Medicine to Improve Traditional Symptom-driven Practice of Medicine: Allowing Early Interventions and Tailoring better-personalized Cancer Treatments -- Chapter 4. AI as a Novel Approach for Exploring ccfNAs in Personalized Clinical Diagnosis and Prognosis: Providing Insight into the Decision-Making in Precision Oncology -- Chapter 5. AI-Enhanced Digital Pathology and Radiogenomics in Precision Oncology -- Part II. Artificial Intelligence and Omics in Precision Oncology -- Chapter 6. Epigenetics Analysis Using Artificial Intelligence in the Era of Precision Oncology -- Chapter 7. Association of Metabolomics with AI in Precision Oncology: Emerging Perspectives for More Effective Cancer Care -- Chapter 8. Artificial Intelligence Application to Microbiomics Data for Improved Clinical Decision Making in Precision Oncology -- Part III. Artificial Intelligence in Cancer Therapy and the Clinical Applications -- Chapter 9. AI and Nanotechnology in Realizing the Goal of Precision Medicine: Tailoring the Best Treatment for Personalized Cancer Treatment -- Chapter 10. Artificial Intelligence-Based Medical Devices Revolution in Cancer Screening: Impact into Clinical Practice -- Chapter 11. Intelligent Drug Design and Use for Cancer Treatment: The Roles of AI and Precision Oncology in Targeting Patient-Specific Splicing Profiles -- Chapter 12. Applying Artificial Intelligence Prediction Tools for Advancing Precision Oncology in Immunotherapy: Future Perspectives in Personalized Care -- Chapter 13. Employing AI-Powered Decision Support Systems in Recommending the Most Effective Therapeutic Approaches for Individual Cancer Patients: Maximizing Therapeutic Efficacy -- Chapter 14. AI-Pathway Companion in Clinical Decision Support: Enabling Personalized and Standardized Care Along Care Pathways in Oncology -- Chapter 15. AI Tools Offering Cancer Clinical Applications for Risk Predictor, Early Detection, Diagnosis, and Accurate Prognosis: Perspectives in Personalised Care -- Chapter 16. Conclusion and Insights into the Future of AI in Precision Oncology.
    Kurzfassung: This book highlights the use of artificial intelligence (AI), big data and precision oncology for medical decision making in cancer screening, diagnosis, prognosis and treatment. Precision oncology has long been thought of as ideal for the management and treatment of cancer. This strategy promises to revolutionize the treatment, control, and prevention of cancer by tailoring tests, treatments and predictions to specific individuals or population groups. In order to accomplish these goals, vast amounts of patient or population group specific data needs to be integrated and analysed to be able to identify key patterns or features which can be used to define or characterize the disease or the response to the disease in these individuals. These patterns or features can be as varied as molecular patterns or features in medical images. This level of data analysis and integration can only be achieved through the use of AI. The book is divided into three parts starting with a section on the use of artificial intelligence for screening, diagnosis and monitoring in precision oncology. The second part: Artificial intelligence and Omics in precision oncology, highlights the use of AI and epigenetics, metabolomics, microbiomics in precision oncology. The third part covers artificial intelligence in cancer therapy and its clinical applications. It also highlights the use of AI tools for risk prediction, early detection, diagnosis and accurate prognosis. This book, written by experts in the field from academia and industry, will appeal to cancer researchers, clinical oncologists, pathologists, medical students, academic teaching staff and medical residents interested in cancer research as well as those specialising as clinical oncologists.
    Materialart: Online-Ressource
    Seiten: XIV, 315 p. 64 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031215063
    URL: https://doi.org/10.1007/978-3-031-21506-3
    DOI: 10.1007/978-3-031-21506-3
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 84
    Online-Ressource
    Online-Ressource
    Grape Rootstocks and Related Species (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Genetics. ; Plant Science. ; Agriculture. ; Genetics and Genomics.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Grape Species -- Grape Rootstocks Breeding -- Grape Scion And Rootstock -- Biotic Stresses And Rootstock Selection -- Abiotic Stresses And Rootstock Selection -- Rootstocks And Vineyard Design Considerations -- Function Of Grape Rootstock -- Choosing Grape Rootstock -- Nursery Stock Certification And Testing Programs -- Commercial Grape Rootstocks Selections. .
    Kurzfassung: This book covers about 20 grape species that are vitally important in breeding programs and provide information on approximately 150 of the most familiar grape rootstocks in the world. Today, grape rootstocks play a fundamental role in resistance to biotic and abiotic stresses and adaptation of grapevine to different environmental conditions, a factor that has opened commercial grape growing up to regions that might otherwise be overlooked. Grape rootstocks can be used for adaptation to a variety of soil conditions, including soil texture, depth, nutrient availability, pH, salinity, lime content, water availability (drought), and water drainage. Rootstocks can also be used to shift scion cultivar; the timing of various key phenological events and indirectly affects vineyard design. There are around 1500 grape rootstocks developed in the world, of which around 50 are commonly used as commercial rootstock. North American species account for around 30 species, and two-third of them have already been used for rootstock breeding at one time or another. However, the most commonly available rootstocks are derived from just three American species (V. berlandieri, V. rupestris, and V. riparia). Therefore, the most common grape rootstocks have a narrow genetic base, and efforts to extend the gene pools for breeding programs by using the other species are of ongoing importance to the industry and scientific community. .
    Materialart: Online-Ressource
    Seiten: XVIII, 201 p. 32 illus., 17 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030994075
    URL: https://doi.org/10.1007/978-3-030-99407-5
    DOI: 10.1007/978-3-030-99407-5
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 85
    Online-Ressource
    Online-Ressource
    Plant Responses to Soil Pollution (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Environmental health. ; Environmental chemistry. ; Biotic communities. ; Plant Science. ; Agriculture. ; Environmental Health. ; Environmental Chemistry. ; Ecosystems.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Soil Acidification and Its Impact on Plants -- Chapter 2: Challenges to Organic farming in Restoration of Degraded Land in India -- Chapter 3: Biochemical and Molecular Responses of Plants exposed to Radioactive Pollutants -- Chapter 4: Cadmium: A Threatening Agent for Plants -- Chapter 5: Effect of Soil Polluted by Heavy Metals: Effect on Plants, Bioremediation and adoptive evolution in plants -- Chapter 6: Plant Responses to Sewage Pollution -- Chapter 7: Soil Pollution caused by Agricultural Practices and Strategies to Manage Them -- Chapter 8: Inorganic Soil Contaminants and their Biological Remediation -- Chapter 9: Phytoremediation of pollutants from soil -- Chapter 10: Impacts of Soil Pollution on Human Health with Special Reference to Human Physiognomy and Physiology -- Chapter 11: Impact of Herbicide Use on Soil Microorganisms -- Chapter 12: Biological Magnification of Soil Pollutants -- Chapter 13: Soil Pollution and Human Health -- Chapter 14: Emission of Greenhouse Gases from Soil: An Assessment of Agricultural Management Practices.
    Kurzfassung: Soil is a vital support system for all life forms, and is directly or indirectly exposed to various pollutants and harmful chemicals. Any pollutant entering the soil system not only affects the quality of the soil, but also the plants and crops growing in it. Further, soil pollution has far-reaching impacts, since harmful chemicals can become biomagnified and enter the food chain, causing severe health concerns. Degraded soils can adversely affect various plant systems by creating biotic and abiotic stress, which increases the chances of biochemical and physiological disorders. Chronic diseases and lower yield have been reported as consequences of soil pollution. Drawing on decades of soil-related research, this book focuses on soil pollution, types of soil pollutants, and their impacts on plant physiological and biochemical systems, along with crop productivity. The book begins with a brief introduction to soil pollution and continues with a discussion of the different types and their effects, together with remediation methods. It highlights various sources of soil pollution such as herbicides, acidification, chemical fertilizers, sewage sludge, heavy metals, and radioactive pollutants. It also covers plant responses to combinations of pollutants, effects of pollutants on plant ultrastructure, interactions between pollutants and plant diseases, and interactions between pollutants and agricultural practices. In closing, it addresses the challenges involved in the restoration of degraded land, side effects of agricultural practices in the form of greenhouse gases, and strategies for mitigating these effects. Plant Responses to Soil Pollution offers an essential guide for students, environmental consultants, researchers and other professionals involved in soil and plant-related research.
    Materialart: Online-Ressource
    Seiten: XXI, 248 p. 27 illus., 17 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811549649
    URL: https://doi.org/10.1007/978-981-15-4964-9
    DOI: 10.1007/978-981-15-4964-9
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 86
    Online-Ressource
    Online-Ressource
    Black cumin (Nigella sativa) seeds: Chemistry, Technology, Functionality, and Applications (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Botanical chemistry. ; Chemistry, Organic. ; Food science. ; Pharmaceutical chemistry. ; Nutrition   . ; Plant Science. ; Plant Biochemistry. ; Organic Chemistry. ; Food Science. ; Pharmaceutics. ; Nutrition.
    Beschreibung / Inhaltsverzeichnis: 1.Introduction to black cumin (Nigella sative): Chemistry, Technology, Functionality and Applications -- Section 1. Nigella sative seeds: Cultivation, Composition and Applications -- 2. Effect of cultivation, fertilization and irrigation practices on Nigella sative yield and quality -- 3. Morphological characters of Nigella sativa -- 4. Micro and macroscopic characterization of traded Nigella sativa seeds using applied systematics techniques -- 5. Composition of Nigella sativa seeds -- 6. Nigella sativa seed peptides (Thionins) -- 7. Black cumin polysaccharides -- 8. Thymoquinone: Chemistry and cunctionality -- 9. Novel Prospective of Nigella sativa Essential Oil Analysis, Culinary and Medicinal Uses -- 10. Rediscovering Nigella Seeds Bioactives Chemical Composition using Metabolomics Technologies -- 11. Health promoting activities of Nigella sativa seeds -- 12. Nigella sativa seed extract in green synthesis and nanocomposite -- 13. Food applications of Nigella sative seeds -- 14. Nutraceutical importance and applications of Nigella sativa seed flour -- 15. Nigella sativa seed cake: nutraceutical significance and applications in the food and cosmetic industry -- 16. Nigella sative seeds in cosmetic products -- 17. Nigella sativa supplementation in ruminant diets: production, health, and environmental perspectives -- 18. Nigella sativa seeds and its derivatives in poultry feed -- 19. Nigella sative Seeds and Its Derivatives in Fish Feed -- Section 2: Nigella sative fixed oil: Chemistry, Technology, Functionality and Applications -- 20. Composition and Functionality of Nigella sativa Fixed Oil -- 21. Effect of processing on the composition and quality of Nigella sativa fixed oil -- 22. Food applications of Nigella sativa Fixed Oil -- 23. Health-Promoting Activities of Nigella sativa Fixed Oil -- 24. Micro- and Nano-encapsulation of Nigella sativa Oil -- 25. Biodiesel Production Potential of Nigella sativa Oil -- Section 3: Nigella sative essential oil: Chemistry, Technology, Functionality and Applications -- 26. Composition and functionality of Nigella sativa essential oil -- 27. Effect of processing on the composition and quality of Nigella sativa essential oil -- 28. Food applications of Nigella sativa essential oil -- 29. Health-promoting activities of Nigella sativa essential oil -- Section 4: Nigella sative seed extracts: Chemistry, Technology, Functionality and Applications -- 30. Composition and Functionality of Nigella sativa Seed Extracts -- 31. Nigella sativa seed extracts in functional foods and nutraceutical applications -- 32. Health promoting activities of Nigella sativa seed extracts.
    Kurzfassung: Recent developments in the field of nutrition have led to increased interest in herbs and medicinal plants as phytochemical-rich sources for functional food, nutraceuticals, and drugs. As research sheds light on the therapeutic potential of various bioactive phytochemicals, the demand for plant extracts and oils has increased. Black cumin or black seeds (Nigella sativa) have particularly widespread nutritional and medicinal applications. In traditional medicine, black seeds are used to manage fatigue and chronic headache. Black seed oil is used as an antiseptic and analgesic remedy and for treatment of joint's pain and stiffness and can be mixed with sesame oil to treat dermatosis, abdominal disorders, cough, headache, fever, liver ailments, jaundice, sore eyes, and hemorrhoids. Thymoquinone, the main constituent in black seed volatile oil, has been shown to suppress carcinogenesis. Black cumin (Nigella sativa) seeds: Chemistry, Technology, Functionality, and Applications presents in detail the chemical composition, therapeutic properties, and functionality of high-value oils, phytochemicals, nutrients, and volatiles of the Nigella sativa seed. Organized by formulation (seeds, fixed oil, essential oil, and extracts), chapters break this seed down into its chemical constituents and explore their role in the development of pharmaceuticals, nutraceuticals, novel food, natural drugs, and feed. Following numerous reports on the health-promoting activities of Nigella sativa, this is the first comprehensive presentation of the functional, nutritional, and pharmacological traits of Nigella sativa seeds and seed oil constituents.
    Materialart: Online-Ressource
    Seiten: XXII, 558 p. 59 illus., 35 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030487980
    Serie: Food Bioactive Ingredients,
    URL: https://doi.org/10.1007/978-3-030-48798-0
    DOI: 10.1007/978-3-030-48798-0
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 87
    Online-Ressource
    Online-Ressource
    Anoikis : How the Extracellular Matrix Regulates Life-or-Death Decisions (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Cell death. ; Cancer Biology. ; Cell Death.
    Beschreibung / Inhaltsverzeichnis: Preface -- Introduction -- The intersection of anoikis resistance and fatty acid metabolism in cancer -- Anoikis resistance in melanoma -- Anoikis mediated by stress-activated MAPK signaling pathways -- Metabolic Regulation of Anoikis -- Metabolic Reprogramming contributes to Anoikis resistance in Cancer Cells -- Role of the nuclear receptors in anoikis -- The roles of anoikis in cervical cancer -- Shc and the control of small GTPase dynamics in cellular anchorage -- Anoikis and the Human Gut Epithelium in Health and Disease -- Epithelial cell extrusion: the prelude to anoikis -- Microtubule modifications and mitochondria: role in anoikis.
    Kurzfassung: This book provides a useful resource for graduate-level cancer cell biology courses. Since the first report, in 1994, of “anoikis”—the apoptosis that occurs when cells lack appropriate contact with the extracellular matrix—over 2,100 papers have been published on this subject. This book is the first comprehensive, in-depth and up-to-date compendium on anoikis. Chapters are authored by some of the leading researchers in the field. This book provides both mechanistic and translational information regarding anoikis, in a convenient format. Mechanistically, the following topics will be addressed in detail: The role of MAP kinase signaling The role of Shc proteins as cellular anchorage sensors The role of cellular metabolism, and fatty acid metabolism in particular, and how they are affected by oncogenic transformation How epithelial cell extrusion – the prelude to anoikis—is regulated in normal and cancer cells The convergence of TGF-b and androgen receptor signaling in the regulation of anoikis This book also discusses the specialized functions and dysregulation of anoikis in the following cancer settings: Colon cancer Melanoma Cervical cancer The book serves to update i nvestigators actively working on problems in the anoikis field, in either experimental or translational settings. For investigators encountering novel biological phenomena that might relate to anoikis, it serve as an entry point to the literature that does not require an extensive background in cell adhesion signaling or apoptosis mechanisms. .
    Materialart: Online-Ressource
    Seiten: VIII, 202 p. 6 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030738563
    URL: https://doi.org/10.1007/978-3-030-73856-3
    DOI: 10.1007/978-3-030-73856-3
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 88
    Online-Ressource
    Online-Ressource
    Novel therapeutic approaches for gastrointestinal malignancies (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Nanotechnology. ; Radiology. ; Molecular genetics. ; Cancer Biology. ; Nanotechnology. ; Radiology. ; Molecular Genetics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Role of selected transcription factors in pancreatic and colorectal cancer growth and metastasis -- Chapter 2. Adiponectin in gastrointestinal malignancies -- Chapter 3. Small molecule-targeted therapies for GI cancers: success and failures -- Chapter 4. Epigenetic biomarkers for the detection of Gastrointestinal Cancers -- Chapter 5. CD151: A Lateral organizer and modulator of Tumor microenvironment in gastrointestinal cancers -- Chapter 6. Targeting Pathways in GI Malignancies -- Chapter 7. Identification of Potential Key Genes Involved In Progression of Gastric Cancer Using Bioinformatics Analysis -- Chapter 8. Recent Development in the biomarkers for the gastric cancer -- Chapter 9. Gastric Cancer and it’s remedy -- Chapter 10. An intergenic variant rs4779584 between SCG5 and GREM1 contributes to the increased risk of colorectal cancer: A meta-analysis -- Chapter 11. Phytochemicals plus nanomaterial’s on colorectal cancer -- Chapter 12. Pancreatic Ductal Adenocarcinoma and Type 2 Diabetes Mellitus: Distant Relatives or the Close Ones? -- Chapter 13. Tumor Biomarkers and Diagnosis of Pancreatic Adenocarcinoma -- Chapter 14. Immunotherapy in Gastrointestinal Malignancies -- Chapter 15. The Role of HIF-1α in Hepatocellular Carcinoma.
    Kurzfassung: This book provides an up-to-date overview of gastrointestinal malignancies, including prevention, early detection, intervention, and life-extending therapeutics. It also assesses various biomarkers used for diagnostics, prognostics and prediction of response to chemoresistance. Further, it discusses the latest trends in the use of small-molecule targeted therapies and immunotherapies as single agents or combination with other treatments. Since resistance to radiation and chemotherapy contribute to the high recurrence and poor survival rates, improving the outcome for GI malignancies is dependent on the introduction of new biomarkers and therapeutic agents. Lastly, the book systematically investigates novel theranostics approaches using nanotechnology for the detection, diagnosis, and personalized treatment of GI malignancies.
    Materialart: Online-Ressource
    Seiten: XII, 259 p. 53 illus., 39 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811554711
    Serie: Diagnostics and Therapeutic Advances in GI Malignancies,
    URL: https://doi.org/10.1007/978-981-15-5471-1
    DOI: 10.1007/978-981-15-5471-1
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 89
    Online-Ressource
    Online-Ressource
    Molecular Biology of Human Cancers (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Medicine Research. ; Biology Research. ; Oncology. ; Cancer Biology. ; Biomedical Research. ; Oncology.
    Beschreibung / Inhaltsverzeichnis: Part I: Molecules, Genes, Cells and Mechanisms -- Chapter 1: An Introduction to Human Cancers -- Chapter 2: Cancer Genetics -- Chapter 3: DNA Damage and DNA Repair -- Chapter 4: Oncogenes -- Chapter 5: Tumor Suppressor Genes -- Chapter 6: Cancer Pathways -- Chapter 7: Cell Death and Replicative Senescence in Cancer -- Chapter 8: Cancer Epigenetics -- Chapter 9: Invasion and Metastasis -- Part II: Human Cancers -- Chapter 10: Leukemias And Lymphomas -- Chapter 11: Pediatric Cancers -- Chapter 12: Cancers of the Skin -- Chapter 13: Colorectal Cancer -- Chapter 14: Bladder Cancer -- Chapter 15: Lung Cancer -- Chapter 16: Renal Cell Carcinomas -- Chapter 17: Liver Cancer -- Chapter 18: Gastric Cancer -- Chapter 19: Breast Cancer -- Chapter 20: Prostate Cancer -- Part Iii: Prevention, Diagnostics and Therapy -- Chapter 21: Cancer Prevention -- Chapter 22: Cancer Diagnostics -- Chapter 23: Cancer Therapy.
    Kurzfassung: This textbook describes the most relevant molecular and biological processes in cancer, how they contribute to the development and progression of individual cancer types in humans, and how insights from molecular cancer research can be applied to improve cancer prevention, diagnostics and treatment. Part I of the textbook summarizes the current fundamental knowledge on the general properties of cancers, the causes of cancer, cancer genetics, genomics and epigenetics. Individual chapters address the functions of DNA damage and repair, oncogenes and tumor suppressors in carcinogenesis and discuss crucial mechanisms in cancer pathogenesis, such as apoptosis and replicative senescence, as well as the most relevant signal transduction pathways and regulatory networks. Part I concludes with a chapter on tumor invasion and metastasis and tumor immunology. In Part II, the most relevant mechanisms acting in individual human cancers (and subtypes) are described in more detail. This central part of the book contains individual sections on the most common human cancers highlighting the diversity in their genetic, molecular and cellular pathogenic mechanisms. How insights from molecular cancer research are translated into improvements in prevention, diagnosis, and treatment is outlined in Part III. This new edition has been extensively revised and includes in particular updated information on cancer genomics, epigenetics, viral carcinogenesis, cancer diagnostics and cancer therapy and a new chapter on lung cancers. Now more than ever, cancer research is an interdisciplinary endeavor that requires a basic knowledge of commonly used terms, facts and concepts. The aim of this book is to provide advanced students and practitioners in various disciplines with this foundation, bridging the gap between standard textbooks of molecular biology, pathology and oncology on the one hand and the specialized cancer literature on the other.
    Materialart: Online-Ressource
    Seiten: XXI, 542 p. 229 illus., 221 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031162862
    URL: https://doi.org/10.1007/978-3-031-16286-2
    DOI: 10.1007/978-3-031-16286-2
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 90
    Online-Ressource
    Online-Ressource
    Nanobiotechnology : Mitigation of Abiotic Stress in Plants (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Agriculture. ; Plant Science. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Abiotic Stress in Plants: Socio-economic Consequences and Crop Plants Responses -- Plant Abiotic Stress Tolerance Mechanisms -- Biotechnology Strategies to Combat Plant Abiotic Stress -- Nanomaterials Fundamentals: Classification, Synthesis and Characterization -- Utilization of Nanobiotechnology in Modern Agriculture -- Contributions of Nano Biosensors in Managing Environmental Stresses under Climate Change Era -- Utilization of Nanobiotechnology to Alleviate Impact of Abiotic Stress in Crop Plants -- Green Synthesis of Nanoparticles Using Different Plant Extracts and their Characterizations -- Applications of Plant-Derived Nanomaterials in Mitigation of Crop Abiotic Stress -- Biosynthesis and Characterization of Microorganisms-Derived Nanomaterials -- Utilization of Nanofertilizers in Plant Tolerance to Abiotic Stress -- Role of Nanomaterials in Regulating Reactive Species as a Signaling Molecule of Abiotic Stress -- Role of Nanomaterials in Regulating Oxidative Stress -- Plant Stress Enzymes Nanobiotechnology -- Plant Stress Hormones Nanobiotechnology -- Effect of Nanoparticle on Plant Growth and Development -- Application of Nanobiotechnology in Overcoming Salinity Stress -- Application of Nanobiotechnology in Overcoming Drought Stress -- Application of Nanobiotechnology in Overcoming Temperature Stress -- Application of Nanobiotechnology in Overcoming Mineral Nutrients Stress -- Nanomaterials Combat Heavy Metals Toxicity by Modulating Oxidative Stress Pathways in Plants -- Nanonutrients: Plant Nutritive and Possible Antioxidant Regulators -- Impact of Nanomaterials Stress on Plants -- Biosafety of Nanomaterials for Plants to Coup with Stress Conditions -- Nanomaterials in Combating Plant Stress: An Approach for Future Applications.
    Kurzfassung: This book provides up-to-date knowledge of the promising field of Nanobiotechnology with emphasis on the mitigation approaches to combat plant abiotic stress factors, including drought, salinity, waterlog, temperature extremes, mineral nutrients, and heavy metals. These factors adversely affect the growth as well as yield of crop plants worldwide, especially under the global climate change. Nanobiotechnology is viewed to revolutionize crop productivity in future. The chapters discuss the status and prospects of this cutting-edge technology toward understanding tolerance mechanisms, including signaling molecules and enzymes regulation in addition to the applications of Nanobiotechnology to combat individual abiotic stress factors. .
    Materialart: Online-Ressource
    Seiten: XVII, 590 p. 98 illus., 88 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030736064
    URL: https://doi.org/10.1007/978-3-030-73606-4
    DOI: 10.1007/978-3-030-73606-4
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 91
    Online-Ressource
    Online-Ressource
    Therapeutic potential of Cell Cycle Kinases in Breast Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Cancer Treatment. ; Cancer Genetic aspects. ; Cancers. ; Cancer Therapy. ; Cancer Genetics and Genomics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 An introduction to breast cancer -- Chapter 2 Current treatment approaches to breast cancer. Chapter 3 Introduction to cell cycle and its regulators -- Chapter 4 Cell cycle and cancer -- Chapter 5 cell cycle dysregulation in breast cancer -- Chapter 6 Molecular Subtypes of breast cancer and CDK dysregulation -- Chapter 7 Breast tumor micro environment and CDks -- Chapter 8 CDK Dysregulation in Breast Cancer: A Bioinformatics Analysis -- Chapter 9 CDK1 Dysregulation in Breast Cancer -- Chapter 10 CDK4/CDK6 dysregulation in estrogen positive receptor breast cancers -- Chapter 11 Therapeutic implications of CDKs in Breast Cancer -- Chapter 12 Novel CDK Inhibitors in Breast Cancer -- Chapter 13 Targeting CDKs with other chemotherapeutic drugs- A combinatorial approach -- Chapter 14 CDKs in cell-cycle progression and therapeutic strategies in Human breast cancer -- Chapter 15 CDk inhibitor for treatment of breast cancer -- Chapter 16 Response of therapy in cell cycle regulatory genes in breast cancer -- Chapter 17 Different cyclins and their significance in Breast cancer.
    Kurzfassung: This book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints and dysregulation in breast cancer. It also examines the prognostic significance of CDKs in breast cancer. and CDK inhibitors for the treatment of metastatic breast cancer. Further, the book discusses the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. Additionally, it examines the role of immunogenic effects of CDK inhibitors, the mechanism of resistance and the current clinical trials in breast cancer treatment. Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. This book is a comprehensive yet concise resource for oncologists and researchers interested in exploring the therapeutic potential of Cyclin-Dependent Kinases in breast cancer.
    Materialart: Online-Ressource
    Seiten: XVII, 373 p. 133 illus., 92 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811989117
    URL: https://doi.org/10.1007/978-981-19-8911-7
    DOI: 10.1007/978-981-19-8911-7
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 92
    Online-Ressource
    Online-Ressource
    Research Methodology in Bioscience and Biotechnology : Research Mindset • Best Practices • Integrity • Publications • Societal Impact (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Biology Technique. ; Biotechnology. ; Plant Science. ; Biological Techniques. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 Science and philosophy -- Chapter 2 Student’s proposal, dissertation, or thesis -- Chapter 3 Research integrity and publication ethics -- Chapter 4 Good Research Practices -- Chapter 5 Publication 101 -- Chapter 7 Lessons learned from Nature’s reports -- Chapter 8 Success can be learned.
    Kurzfassung: This monograph offers a comprehensive guide to good research practices and mindsets, covering a wide range of topics across 8 chapters. Readers will find numerous themes and strategies that can help them develop their research skills and achieve their objectives, from effective proposal writing to stress management and upskilling. This book explains the purpose, process, tips, and mistakes of writing proposals, theses, articles, and reviews in clear and straightforward language, allowing readers to develop good research plans. By applying the advice and insights offered in this book, students and researchers can improve the quality of their work, cultivate research integrity, and develop good publication plans, write well, and reduce rejection rates. Research outputs will be more likely to be of high quality if students and researchers are encouraged to cultivate these pieces of advice. The focus of the book is not solely on the outcomes of research. Rather, it also delves into mindset, habits, adaptability, time management, stress management, recent tools for upskilling, planning, and execution. Throughout the book, the author seeks to instill a growth mindset in the readers, encouraging them to develop positive research habits and behaviors. KPIs, particularly publications, shall not be used as a reason to erode research integrity and ethnicity; therefore, plagiarism, self-citation, falsifying data, exaggerating findings, authorship in publications, the use of AI tools, CRediT, and COPE are discussed. This book contains interviews with high-profile researchers, top management at institutions, policy advisers, etc., whose opinions and advice the readers will find valuable. Overall, this all-in-one guide is an essential resource for postgraduate students, post-doctoral fellows, and academics who are struggling to find a survival strategy in the rapidly changing research environment. The book assists readers in developing right mindset, planning their research and publications, and in achieving their predetermined objectives. .
    Materialart: Online-Ressource
    Seiten: XXIII, 241 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819928125
    URL: https://doi.org/10.1007/978-981-99-2812-5
    DOI: 10.1007/978-981-99-2812-5
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 93
    Online-Ressource
    Online-Ressource
    Genome Engineering for Crop Improvement (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Plant genetics. ; Agriculture. ; Plant Science. ; Plant Genetics. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Source-Sink relationships and its effect on plant productivity: manipulation of primary carbon and starch metabolism -- Transgenic Approaches to Develop Virus Resistance in Rice -- Virus free improved food in the era of bacterial immunity -- Host-induced gene silencing (HIGS): An emerging strategy for the control of fungal plant diseases -- Genetic Engineering for Biotic Stress Management in Rice -- Genome improvement for rust disease resistance in wheat -- Novel technologies for transgenic management for plant virus resistance -- Cisgenesis: Engineering plant genomes by harnessing compatible gene pools -- Improving biotic and abiotic stress tolerance in plants: A CRISPR-Cas approach -- RNA interference (RNAi) in Functional Genomics of Wheat.
    Kurzfassung: This book serves the teachers, researchers and the students as a handy and concise reference as well as guidebook while designing and planning for use of the advanced technologies for crop improvement. The content of the book is designed to cover the latest genome engineering techniques for crop improvement. The conventional breeding has got its limitations such as non-availability of desired genes within the genepool. In many cases, breeding has been highly used and it has nearly reached its highest limit so far as the productivity and production of crops are concerned. However, with increasing need of food and decreasing resources, including water, land, labour, etc., to feed the growing population, the alternative available ways of increasing crop productivity need to be explored and exploited. Genome engineering has a wide scope that includes technologies such as genetic engineering and transgenesis, RNA technologies, CRISPR, cisgenics and subgenics for better productivity and more efficient biotic and abiotic stress management. Therefore, the book is planned to enlighten the readers with the advanced technologies with examples and case studies, whenever possible. Efforts will be made to emphasize on general efforts on various major food crops; however, it would also be made clear that such efforts could be taken as proofs of concepts and that this could be extrapolated keeping the demand in mind.
    Materialart: Online-Ressource
    Seiten: XVII, 264 p. 25 illus., 24 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030633721
    Serie: Concepts and Strategies in Plant Sciences,
    URL: https://doi.org/10.1007/978-3-030-63372-1
    DOI: 10.1007/978-3-030-63372-1
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 94
    Online-Ressource
    Online-Ressource
    Inflammation, Infection, and Microbiome in Cancers : Evidence, Mechanisms, and Implications (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Human physiology. ; Immunology. ; Cancer Biology. ; Medical Microbiology. ; Biomedical Research. ; Human Physiology. ; Immunology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: The Microbiome And The Hallmarks Of Cancer -- Chapter 2: Microbiome In Human GI Cancers -- Chapter 3: The Gut Microbiome And Colorectal Cancer -- Chapter 4: Salmonella Infection In Human Cancers -- Chapter 5: Biomarkers Of Esophageal Cancers And Precancerous Lesions -- Chapter 6: Epithelial And Immune Cell Responses To Helicobacter Pylori That Shape The Gastric Tumor Microenvironment -- Chapter 7: Microbiome And Liver Cancer -- Chapter 8: THE MICROBIOME AND UROLOGIC CANCERS -- Chapter 9: Role Of Infections And Tissue Inflammation In The Pathology Of The Fallopian Tube And High-Grade Serous Ovarian Cancer -- Chapter 10: Commensal Microbes And Their Metabolites: Influence On Host Pathways In Health And Disease -- Chapter 11: Dietary And Microbiome In Cancer Prevention -- Chapter 12: Autophagy And Cancer-Current Biology And Drug Development -- Chapter 13: Mitochondrial Regulation Of Inflammation In Cancer -- Chapter 14: Modern Germ-Free Study Designs And Emerging Static Housing Technology In A Growing ‘Human Microbiome’ Market -- Chapter 15: Machine Learning In Identification Of Disease-Associated Microbiota -- Chapter 16: Mediation Analysis Of Microbiome Data And Detection Of Causality In Microbiome Studies.
    Kurzfassung: This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.
    Materialart: Online-Ressource
    Seiten: XII, 509 p. 31 illus., 28 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030679514
    Serie: Physiology in Health and Disease,
    URL: https://doi.org/10.1007/978-3-030-67951-4
    DOI: 10.1007/978-3-030-67951-4
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 95
    Online-Ressource
    Online-Ressource
    The Extracellular Matrix and the Tumor Microenvironment (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Cytology. ; Clinical biochemistry. ; Cancer Biology. ; Cell Biology. ; Medical Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Small leucine-rich proteoglycans regulate cancer cell growth, apoptosis-and associated inflammation -- Chapter 2: The role of decorin in cancer -- Chapter 3: The mystery of syndecan-1 in tumor development and progression -- Chapter 4:Syndecan-2 Biology and its Role in Colorectal Carcinoma -- Chapter 5: Versican in Tumor Progression, Tumor-Host Interactions and Cancer Immunotherapy -- Chapter 6:Circulating proteoglycans/glycosaminoglycans as cancer biomarkers -- Chapter 7: Hyaluronan in the Extracellular Matrix of hematological and solid tumors. Its biological effects" -- Chapter 8: Heparanase: a paramount enzyme for cancer initiation, progression and metastasis -- Chapter 9: Laminins and matrix metalloproteinases connection: a subtle relationship that can go wrong in a tumor context, particularly if CD44 gets involved -- Chapter 10:Basement membrane, collagen, and fibronectin: physical interactions with cancer cells -- Chapter 11: Integrins in cancer: re-focusing on the tumor microenvironment -- Chapter 12: Adipose compounds in breast tumor extracellular matrix -- Chapter 13: Extracellular matrix as a metabolic niche in cancer -- Chapter 14: The role of inflammatory cells in tumor angiogenesis -- Chapter 15: Cancer angiogenesis and its master regulator perlecan -- Chapter 16: The microRNA-extracellular matrix interplay in breast cancer -- Chapter 17: The impact of the extracellular matrix on immunotherapy success -- Chapter 18: Exploiting hyaluronan-CD44 network in tumor therapy.
    Kurzfassung: This book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression. Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression. Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM. This book is an interesting read for anyone who want to know more about ECM and cancer biology. Early career scientists can use it as an introduction to the field, offering an excellent tool for studying ECM. Advanced researchers and clinicians can gain a broader overview of the subject, considering the role of ECM for influencing every cancer hallmark as well as in the response of cancer treatments. The work serves to inspire future research and shows that the ECM should be considered as an important factor in the development of cancer therapeutics. The series "Biology of Extracellular Matrix" is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
    Materialart: Online-Ressource
    Seiten: X, 494 p. 40 illus., 34 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030997083
    Serie: Biology of Extracellular Matrix, 11
    URL: https://doi.org/10.1007/978-3-030-99708-3
    DOI: 10.1007/978-3-030-99708-3
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 96
    Online-Ressource
    Online-Ressource
    Mangroves: Ecology, Biodiversity and Management (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Botany. ; Ecology . ; Biotic communities. ; Plant Science. ; Ecology. ; Ecosystems.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Mangroves: Types and Importance -- Chapter 2. Biogeography of the Mangrove Ecosystem: Floristics, population structure and conservation strategies -- Chapter 3. Mangroves as feeding and breeding grounds -- Chapter 4. Factors influencing mangrove ecosystems -- Chapter 5. Energy Flux in Mangrove Ecosystems -- Chapter 6. Nitrogen and Phosphorus budget in mangrove ecosystem -- Chapter 7. Mangroves as a Carbon Sink/Stocks -- Chapter 8. Estimation of Blue Carbon stock of mangrove ecosystem and its dynamics in relation to hydrogeomorphic settings and land use-landcover -- Chapter 9. Responses of Mangrove Ecosystems to Climate Change in the Anthropocene -- Chapter 10. Roles of mangroves in combating the climate change -- Chapter 11. Role of mangroves in pollution abatement -- Chapter 12. Measurement and modeling of above-ground root systems as attributes of flow and wave attenuation function of mangroves -- Chapter 13. Mangrove as Natural Barrier to Environmental Risks and Coastal Protection -- Chapter 14. Diversity and community structure of polychaetes in mangroves of Indian coast -- Chapter 15. Structure and Diversity of Plants in Mangrove Ecosystems -- Chapter 16. Livelihood of Forest Dependent Dwellers in relation to the Exploitation of Resources at the fringe of Indian Sundarban -- Chapter 17. The Roles of Mangroves in Sustainable Tourism Development -- Chapter 18. Aquaculture in Mangroves -- Chapter 19. Ecological Valuation and Ecosystem Services of Mangroves -- Chapter 20. Management Action Plans for Development of Mangrove Forest Reserves -- Chapter 21. Geo-spatial tools for Mapping and Monitoring Coastal Mangroves.
    Kurzfassung: Mangroves are one of the most productive and biologically important blue-carbon ecosystems across the coastal intertidal zone of earth. In the current scenario of serious environmental changes like global warming, climate change, extreme natural disasters, mangrove forests play a vital role in mitigating greenhouse gas emissions and maintaining ecosystem balance. Mangroves are unique ecosystems with rich biological diversity of different taxonomic groups exhibiting great ecological and commercial importance. The book consolidates existing and emerging information on ecology of mangroves, with a special reference to their biodiversity and management. It emphasizes on the role of mangroves in providing various ecological services. The book is a comprehensive compilation covering all aspects of mangrove ecology. It is useful for students and researchers in ecology, plants sciences and environmental sciences. .
    Materialart: Online-Ressource
    Seiten: XIII, 551 p. 107 illus., 80 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811624940
    URL: https://doi.org/10.1007/978-981-16-2494-0
    DOI: 10.1007/978-981-16-2494-0
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 97
    Online-Ressource
    Online-Ressource
    Breast Cancer: From Bench to Personalized Medicine (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Cancer. ; Cancer Epidemiology. ; Cancer Genetic aspects. ; Cancer Biology. ; Cancer Epidemiology. ; Cancer Genetics and Genomics.
    Beschreibung / Inhaltsverzeichnis: Module 1_Overview of Breast Cancer -- Module 2_Cell and Molecular Biology of Breast Cancer-Diagnosis and Prognosis -- Module 3_Breast Cancer Treatment.
    Kurzfassung: This book provides detailed information on the etiology, pathogenesis, diagnosis, prognosis, and treatment strategies for breast cancer. The first section of the book presents epidemiology, risk factors, histopathological, immunohistochemistry, and molecular subtypes of breast cancer based on the receptor status. It also discusses the association of breast cancer with other hormone-sensitive cancers. The second section of the book covers cover BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression of breast cancer, and noninvasive biomarkers for the early detection of breast cancer. It also discusses the role of epigenetic modifications and non-coding RNAs in breast cancer metastasis and explores these as the biomarkers and therapeutic targets for breast cancer therapy. Further, it discusses the role of fibrinolytic mechanisms and circulating tumor cells in breast cancer diagnosis, prognosis, and treatment. The book also provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors to treat breast cancer. Finally, it offers potential new options for personalized therapies for breast cancer patients, including optimizing drug dosage and identifying genetic changes associated with cancer symptom occurrence and severity.
    Materialart: Online-Ressource
    Seiten: XVII, 536 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811901973
    URL: https://doi.org/10.1007/978-981-19-0197-3
    DOI: 10.1007/978-981-19-0197-3
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 98
    Online-Ressource
    Online-Ressource
    Hormonal Pathology of the Uterus (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Cancer. ; Endocrinology. ; Pathology. ; Cancer Biology. ; Endocrinology. ; Pathology.
    Beschreibung / Inhaltsverzeichnis: 1. Biophysiology of the uterus: development, cyclic changes, menopause -- 2. Hormonal effects in reproductive technology (ovulation stimulation, in vitro fertilization) -- 3. Hormonal role and therapy in common benign uterine lesions: endometrial polyps, leiomyomas, adenomyosis -- 4. Endometrial hyperplasia; precancerous lesions of the endometrium. Hormone therapy -- 5. Endometrial Carcinoma. Endometriosis, Hormonal Role in Carcinogenesis. Hormonal Therapy -- 6. Menopausal Hormone Therapy. Contraceptives -- 7. Replacement hormone therapy for gender dysphoria and congenital sexual anomalies -- 8. Hormone therapy for endometrial neoplasia related to breast cancer therapy (Tamoxifen) -- 9. Endometrial histopatholigic changes in hormonal therapy (contraceptives, ovulation stimulation, hormone replacement therapy, hormonal antitumoral therapy).
    Kurzfassung: Hormonal influences, both natural and iatrogenic, are implicated in the most frequent health issues of women. Endometrial cancer is now the most common gynecologic cancer in the United States and the industrialized world. This cancer is strongly related to hormonal and metabolic factors. In addition, breast cancer treated with hormone therapy (Tamoxifen) may, in some cases, be associated with uterine pathology. Hormone therapy is used to improve the physiological effects and counteract abnormal and deleterious effects of “natural” hormonal activity. Millions of women receive hormone therapy at some point of their life: using oral contraceptives, reproductive technology, treatment for post-menopausal symptoms, among other uses. This book addresses a range of women’s health issues, from fertility to neoplasms, and their relationship with natural and iatrogenic hormonal effects. Chapters include clinical and pathological descriptions, theoretical and practical medical issues, and original studies and cases. Controversial issues in certain hormone therapies are presented with updated concepts based on clinical studies and novel statistical methods. The book will be useful for specialized and general physicians, oncologists, endocrinologists, researchers, medical students, and others in the field of women’s health. .
    Materialart: Online-Ressource
    Seiten: VIII, 185 p. 66 illus., 59 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030384746
    Serie: Advances in Experimental Medicine and Biology, 1242
    URL: https://doi.org/10.1007/978-3-030-38474-6
    DOI: 10.1007/978-3-030-38474-6
    DDC: 571.978
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 99
    Online-Ressource
    Online-Ressource
    Food and Potential Industrial Applications of Bambara Groundnut (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Food science. ; Food security. ; Plant Science. ; Food Science. ; Food Security.
    Beschreibung / Inhaltsverzeichnis: 1. Bambara groundnut perspective -- 2. Agricultural production practices of bambara groundnut -- 3. Pre- and post- harvest handling and storage of bambara grains -- 4. Characteristics of bambara groundnut: description, structure and composition -- 5. Limitations to bambara groundnut utilization -- 6. Bambara groundnut starch -- 7. Bambara groundnut protein -- 8. Phytochemicals in bambara groundnut -- 9. Traditional food uses of bambara groundnut -- 10. Bambara groundnut in complementary feeding -- 11. Microbiology and safety of bambara groundnut -- 12. Potential industrial applications of bambara -- 13. Conclusions and future trends.
    Kurzfassung: Bambara groundnut (Vigna subterranea) is a crop native to the Bambara tribe of Mali and is grown as a subsistence crop in Africa. Recent advances in research, however, have brought the crop to the forefront of the sustainable agriculture movement. The Bambara plant is highly drought tolerant and rich in protein and carbohydrates, including starch. These macromolecules have enormous industrial potentials. For example, the starch in Bambara grain has been found to exhibit higher (double) viscosity than conventional corn starch. Modified Bambara groundnut starch has been used to produce edible bioplastics that could be upgraded industrially to suit the fourth industrial revolution shift. Bambara plants are also a natural source of soluble fiber, which is gluten-, lactose- and cholesterol-free, with potential as a stabiliser, thickener and gelling agent as well as a cryoprotectant in frozen products. The health benefits include lowering of cholesterol levels, levelling of blood glucose and as a detoxing aid. Furthermore, several researchers have explored the grain either alone or as composite with cereal and tubers for the development of value-added products. Food and Potential Industrial Applications of Bambara Groundnut presents in a clear, coherent way the research findings on Bambara grain and its status as a promising food and industrial crop.
    Materialart: Online-Ressource
    Seiten: XVII, 237 p. 46 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030739201
    URL: https://doi.org/10.1007/978-3-030-73920-1
    DOI: 10.1007/978-3-030-73920-1
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
  • 100
    Online-Ressource
    Online-Ressource
    Hormones and Plant Response (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Botany. ; Plants. ; Stress (Physiology). ; Botanical chemistry. ; Plant biotechnology. ; Agriculture. ; Plant Science. ; Plant Signalling. ; Plant Stress Responses. ; Plant Biochemistry. ; Plant Biotechnology. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Plant hormones and plant defense response against pathogens (Marocco) -- Chapter 2. Plant hormones and nutrient deficiency responses (Romera) -- Chapter 3. Seed germination: Explicit cross talk between hormones and ROS (Kar) -- Chapter 4. Hormones and light-regulated seedling development (Datta) -- Chapter 5. Light-mediated regulation of plant hormone metabolism (Freschi) -- Chapter 6. Hormones in photoperiodic flower induction (Kopcewicz) -- Chapter 7. Recent insight into auxin mediated molecular cross talk events associated with regulation of root growth and architecture during abiotic stress in plants(Mukherjee) -- Chapter 8. Abscisic acid and fruit ripening: Its role in grapevine acclimation to the environment, a case study (Berli) -- Chapter 9. Biosynthesis and molecular mechanism of brassinosteroids action (Bajguz) -- Chapter 10. Regulatory role of melatonin in the redox network of plants and plant hormones relationship in stress (Arnao) -- Chapter 11. Tryptophan: A precursor of signaling molecules in higher plants (Corpas) -- Chapter 12. GABA and proline metabolism in response to stress (Signorelli).
    Kurzfassung: This book provides an overview of the recent advancements for plant scientists with a research focus on phytohormones and their responses (nature, occurrence, and functions) in plant cells. This book focuses on the role of phytohormones in biosynthesis, plant sexual reproduction, seed germination and fruit development and ripening. It further highlights the roles of different phytohormones on signaling pathways as well as on photoperiodism/Gravitropism/Thigmotropism. The volume also explores the role of phytohormones in gene expression and plant melatonin and serotonin and covers how plant hormones react in case of stress/defence response (metals/metalloids/pathogen). Last but not least, this volume also discusses phytohormones in the context of new regulatory molecules such as Nitric oxide, hydrogen sulfide, melatonin.
    Materialart: Online-Ressource
    Seiten: VIII, 314 p. 36 illus., 28 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030774776
    Serie: Plant in Challenging Environments, 2
    URL: https://doi.org/10.1007/978-3-030-77477-6
    DOI: 10.1007/978-3-030-77477-6
    DDC: 580
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    E-BOOKS (AWI ONLY)
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...