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  • 1
    Online Resource
    Online Resource
    Ecosystem and Species Habitat Modeling for Conservation and Restoration (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology Methodology. ; Biotic communities. ; Plant ecology. ; Ecological Modelling. ; Ecosystems. ; Plant Ecology.
    Description / Table of Contents: 1. Modelling tools and plausible scenarios in science-policy to improve evidence based decision making for human-well-being -- 2. Basic Introduction to Species Distribution Modelling -- 3. Machine Learning based predictive modelling approaches for better understanding evolutionary history, distribution and niche occupancy: Experience from Western Ghats -- 4. Mapping the impact of climate change on eco-sensitive hotspots using species distribution modelling (SDMs) – Gaps, Challenges and Future Perspectives -- 5. Approaches for modelling the climate change impacts on ecosystems -- 6. Developing a Bayesian Model of Climate-Induced Lake Overturn in Talisay, Taal Lake -- 7. Global sensitivity and uncertainty analysis of MaxEnt model: Implications in species habitat projections -- 8. Tree species diversity and richness patterns reveal high priority areas for conservation in Eswatini -- 9. Improving the conservation status of a threatened tree (Acer sikkimensis Miq. syn. Acer hookeri Miq.) through standardization of seed germination protocol and using ecological niche modeling -- 10. Ecological Niche Modeling of the endemic Himalayan near-threatened treeline conifer Abies spectabilis (D.Don) Mirb. in the Indian Central Himalaya -- 11. Modeling the distribution of a medicinal plant Oroxylum indicum (L.) Kurz for its conservation in Arunachal Pradesh -- 12. Habitat Suitability and Niche Modeling for Conservation and Restoration of Aconitum heterophyllum Wall. in Temperate Himalayan Forest Ecosystem -- 13. Application of species distribution modeling for conservation and restoration of forest ecosystems -- 14. Habitat suitability analysis of Asiatic Elephants (Elephas maximus) in the Tropical Moist Deciduous Forest of Assam using Analytic Hierarchy Process (AHP) -- 15. Factors Affecting the Habitat Suitability of Eastern Swamp Deer (Rucervus duvaucelii ranjitsinhi Groves, 1982) in Manas National Park and Implication for Terai Grassland Restoration -- 16. Evaluating Potential Habitats of Chital, Sloth Bear and Jungle Cat in Selected Areas of Central Indian Landscape -- 17. Habitat suitability modeling of Tor tor (Hamilton, 1822) in the Indian drainage systems using MaxEnt -- 18. Modelling the influence of Marine Fishery Advisories on the reduction of Carbon Dioxide emissions for Odisha under varying Climate Change Scenarios using CMIP models – an evidence-based approach for policymaking -- 19. Impacts of pollution on tropical montane and temperate forests of South Asia: Preliminary studies by post graduate students in India and Sri Lanka -- 20. Selection of strategic sampling sites for river quality assessments near mined areas as a policy handle for low-impact development and biodiversity conservation – a case study of River Godavari -- 21. Ecological niche modeling predicts the potential area for cultivation of Melia dubia Cav. (Meliaceae): a promising tree species for agroforestry in India -- 22. Proportions of change in the airborne particulate matter (PM10) concentrations across selected states in Peninsular India - a study of decadal, pre-pandemic trends for planning restoration -- 23. Decomposition of Sunflower Cuttings and its Impact on Soil Fertility of Rice Terraces (Payoh) in Banaue, Ifugao, Philippines -- 24. Forest ecosystem modeling for policy planning: A review -- 25. Ecological Carrying Capacity Modelling and Sustainability Assessment of the Seven Lakes of San Pablo City, Laguna, Philippines -- 26. Assessment of the contribution of Fresh Water Ecosystem Services to the Hydropower Sector in the Kura-Araz basin -- 27. Eutrophication modelling of Chilika Lagoon using an artificial neural network approach.
    Abstract: This edited book is focused on SDG 15. This volume covers aspects of species and ecosystem modeling in understanding the complexity of ecological systems, restoration, protected area management, and species conservation. The book follows a systematic and situation-sensitive approach to discuss ecosystem and species modeling tools, approaches, science, case studies, opportunities, and gaps for enhancing conservation efforts, ensuring ecosystem resilience, and addressing sustainability issues. The book emphasizes on science, innovations, case studies, and strategic relevance as main pillars of using ecosystem and species modeling tools and implementing the outcomes and results. In addition, clear conceptual frameworks, elaborated methodologies, and their applications are included to support policy planning and interventions to reduce and reverse human encroachment in human-dominated natural ecosystems, their degradation, and loss of important species and ecosystem services. Essential information with a special focus on advances and opportunities in advancing the implementation of results and outputs of the modeling tools, challenges and constraints for addressing loss of ecosystem services, designing and implementing sustainable landscape restoration, environmental risk assessment, and finally understanding policy implications and concerns for mainstreaming modeling results in conservation planning and decision-making is included in the book. Further topics include ultimate translational value of modeling tools and efforts across transitional ecosystems and species habitat to provide better evidence to influence the nature-based solutions (NbS) and ecosystem health assessment using Red List of Ecosystems (RLE). The emerging roles of integrative socio-ecological as well as techno-cultural factors in promoting the relevance of ecosystem and species modeling is one of the key features of this book. This edited volume is of interest and useful to researchers, students, scholars, policy makers, forest managers, consultants, and policy makers in the fields of protected area management, forest department, conservation, modeling, climate change, and sustainability science, and also authors engaged in IPBES, IPCC, and several other assessments.
    Type of Medium: Online Resource
    Pages: XXXV, 570 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819901319
    URL: https://doi.org/10.1007/978-981-99-0131-9
    DOI: 10.1007/978-981-99-0131-9
    DDC: 577
    Language: English
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  • 2
    Online Resource
    Online Resource
    Theories in Ecological Risk Assessment (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Environmental sciences Mathematics. ; Environment. ; Conservation biology. ; Statistics . ; Ecology. ; Mathematical Applications in Environmental Science. ; Environmental Sciences. ; Conservation Biology. ; Statistics.
    Description / Table of Contents: 0. Introduction - Ecologist in Wonderland -- Part 1. Linking Ecotoxicology and Ecology -- Chapter 1. Basic Concepts of Ecological Risk Assessment -- Chapter 2. Population-level assessment -- Chapter 3. Population models of extinction -- Chapter 4. Population level assessment using the canonical model -- Part 2. Models for ecotoxicology -- Chapter 5. Species Sensitivity Distribution in Ecological Risk Assessment -- Chapter 6. BLM: A model for predicting metal toxicities -- Chapter 7.Mathematical models for chemical mixtures -- Chapter 8.Statistics and related topics.
    Abstract: This book introduces various mathematical models used in ecological risk assessment, primarily discussing models used in hazard assessment. The book aims to link ecology and conservation biology with risk assessments, bringing together the knowledge of ecotoxicology and ecology for effective risk assessment. The first part describes population-level assessment in ecological risk assessment. The chapters cover current methodologies for ecological risk assessment, individual-level assessment, population dynamics models for population-level assessment, case studies, mathematical models for population extinctions, the derivation of mean time to extinction (MTE) and their case studies. The second part of the book discusses the mathematical models involved in hazard assessments. It introduces the method of risk assessment using species sensitivity distributions (SSDs), hazard assessment of metals, chemical mixtures using the Michaelis-Menten equation, basic elements of statistics and related topics. Expected readers are risk assessors in governments and public sectors, students and young researchers interested in environmental science. The book is made accessible and easy to follow by beginners in mathematical biology and theoretical ecology.
    Type of Medium: Online Resource
    Pages: XIV, 202 p. 90 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903092
    Series Statement: Theoretical Biology,
    URL: https://doi.org/10.1007/978-981-99-0309-2
    DOI: 10.1007/978-981-99-0309-2
    DDC: 577
    Language: English
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  • 3
    Online Resource
    Online Resource
    River Dynamics and Flood Hazards : Studies on Risk and Mitigation (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotic communities. ; Freshwater ecology. ; Marine ecology. ; Ecosystems. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Part (I) Introduction to river hazards and their management: Chapter 1. Natural River Hazards: Their Impacts and Mitigation Techniques -- Chapter 2. Assessment of sediment hazard and associated measurement -- Chapter 3. Modelling approach to study the riverine flood hazard of lower Damodar river -- Chapter 4. Field measurement of accumulated surface water and infiltration depth in a flood-prone Langol catchment of Manipur valley region -- Chapter 5. Soil erosion analysis with respect to land use / land cover change in Godavari basin -- Part (II) Stability of Hydraulic Structures and Sediment Transport: Chapter 6. Stability of hydraulic structures against erosion and scour due to water jets -- Chapter 7. Stabilization of Manmade Embankments at Indian Sundarban Estuary through Turbulence Control at Flow-Sediment Interface: Field Survey and Flume Experimentation -- Chapter 8. A Review of Sedimentation on Different Types of Weirs -- Chapter 9. A Review on Parametric Studies of Piano Key Weir -- Chapter 10 Influence of boundary condition on the modified 2D shallow water model near the flow-structure interaction zone: a case study in Brahmaputra River -- Chapter 11. A Review on Estimation Methods of Scour Depth around Bridge Pier -- Chapter 12. Estimation of Shear force Distribution in Two-stage open channel using SVM and ANFIS -- Chapter 13. Sediment transport modelling through machine learning methods: Review of current challenges and strategies -- Chapter 14. Impact of Anthropocene on the fluvial sediment supply: The Mahanadi River basin perspective -- Chapter 15. Assessment of sediment hazards by bed level variations around the bridge pier -- Chapter 16. Equation development for equilibrium bed load -- Part (III) Hydrological hazards and ecological restoration: Chapter 17. Flood mitigation with river restoration using Porcupine systems -- Chapter 18. Flood prioritisation of basins based on geomorphometric properties using Morphometric analysis and Principal component analysis: A case study of the Maner River basin -- Chapter 19. Flood modelling of Krishna river at Sangli using HEC-RAS -- Chapter 20. Development of Machine Learning based Flood Prediction Model for Godavari River Basin -- Chapter 21. Field study on soil organic matter content in inundation areas of Langol catchment by loss- on-ignition” method -- Chapter 22. Agricultural Drought Assessment using Satellite based Surface Soil Moisture Estimate -- Chapter 23. A Review on Hydrodynamics of Vegetated Streams -- Chapter 24. Analysis of Stormwater Drainage Network of the Central Zone in the Surat City by Using SWMM 5.1 Software -- Chapter 25. Review of state-of-the-art research on river hydrological hazards, restoration and management -- Chapter 26. Erosion Susceptibility Mapping based on Hypsometric Analysis using Remote Sensing and Geographical Information System Techniques -- Part (IV) Climate change and Global warming issues: Chapter 27. Climate Change Implication and Adaptation for River systems -- Chapter 28. Non-parametric approaches to identify rainfall pattern in semi-arid regions: Ranipet, Vellore, and Tirupathur districts, Tamil Nadu, India -- Chapter 29. Decadal-based analysis of hydrological components in the Kesinga sub-catchment in Mahanadi Basin: An assessment of climate variability impact -- Chapter 30. Prediction of Future Rainfall in the Upper Godavari Basin Using Statistical Downscaling Model -- Chapter 31. Projecting Future Maximum Temperature Changes in River Ganges Basin using Observations and Statistical Downscaling Model (SDSM) -- Chapter 32. Trend Assessment of Rainfall over Mumbai and Pune Cities -- Chapter 33. Evaluation of Potential lakes Susceptible to GLOF using Multi-Criteria Assessment in Jhelum Sub-basin of Indus Basin.
    Abstract: This edited book covers all aspects of River related disasters, challenges, and opportunities. Step-by-step descriptions are provided of river dynamics and associated hazards, and their applications in hazard assessments, accompanied by several experimental, filed and numerical studies. In addition, a systematic table of content is given to aid in identifying River hazards challenges and opportunities. Essential information is provided on River dynamics, hydrological processes and climate change issues, and an individual chapter is devoted to ecological restoration and river hazard management. Further topics include the stability of hydraulic structures, sediment transport, and debris flow in the hilly streams. This book will provide students, researchers, scientists, water resources managers with a comprehensive overview of the River dynamics and flood hazards in various sectors of water-related disasters and will enable them to explore the scope of application of the computational techniques and will enable them to explore the scope of River related disasters, allied branches and their field-specific problems. Professionals and policymakers may also explore the implementation of these approaches in their workplace to tackle complex river dynamics and hydrological phenomena occurring in their study area.
    Type of Medium: Online Resource
    Pages: X, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811971006
    Series Statement: Disaster Resilience and Green Growth,
    URL: https://doi.org/10.1007/978-981-19-7100-6
    DOI: 10.1007/978-981-19-7100-6
    DDC: 577
    Language: English
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  • 4
    Online Resource
    Online Resource
    Circulating Tumor Cells : Advances in Liquid Biopsy Technologies (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Cancer Therapy. ; Tumour Biomarkers.
    Description / Table of Contents: Part 1. CTC Technologies -- Affinity -- Physical -- ctDNA -- miRNA -- Exosomes -- Part 2 -- Biology of CTC -- Dormancy -- Culture -- EMT -- ctDNA and Exosomes -- Cells in circulation with CTC -- Part 3 -- CTC Analysis -- IHC, FISH, and other molecular assays -- Functional characterization -- Advanced microscopy and AI -- Analysis of non-cellular circulating markers -- Part 4 -- Clinical Applications of the Liquid Biopsy -- Early detection and cancer screening -- Prognosis and therapeutic monitoring -- Applications in Clinical Trials -- Applications in Drug Development.
    Abstract: It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other emerging aspects of the liquid biopsy, including circulating tumor DNA and methylated DNA (ctDNA, ct meDNA), ctRNA, ct miRNA, circulating tumor proteins (and other) biomarkers and circulating tumor derived exosomes (ctExosomes).
    Type of Medium: Online Resource
    Pages: XXI, 668 p. 77 illus., 72 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031229039
    Series Statement: Current Cancer Research,
    URL: https://doi.org/10.1007/978-3-031-22903-9
    DOI: 10.1007/978-3-031-22903-9
    DDC: 571.978
    Language: English
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  • 5
    Online Resource
    Online Resource
    Psammic Peinobiomes : Nutrient-Limited Ecosystems of the Upper Orinoco and Rio Negro Basins (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Soil science. ; Plant ecology. ; Geomorphology. ; Ecophysiology. ; Conservation biology. ; Ecology . ; Ecosystems. ; Soil Science. ; Plant Ecology. ; Geomorphology. ; Ecophysiology. ; Conservation Biology.
    Description / Table of Contents: 1 Introduction -- Part I: Forest and woodland biomes -- 2 White sand ecosystems in the Amazon basin: geographic distribution, distinctive features, and ecology. An overview -- 3 The forests of the Rio Negro basin in the north-western Amazon: a phytosociological classification -- 4 Amazon caatinga complex: sclerophyllous vegetation on nutrient-poor white sand soils -- Part II: Meadow biomes -- 5 Mapping white-sand ecosystems by integrating Global PALSAR-2 and SENTINEL-1 with NDVI (LANDSAT data) -- 6 The study areas: landscapes and soils -- 7 Soil properties, formation, distribution, and classification -- 8 Origin and sources of sand: from highlands to lowlands -- 9 Sand dynamics and distribution: a geo-sedimentological approach -- 10 Features and trends of meadow landscape evolution -- 11 Meadow phytodiversity: flora, endemism, vegetation types, and geographic distribution patterns -- 12 Synthesis: white-sand and meadow-vegetation relationships.
    Abstract: The book represents a multidisciplinary approach to understanding soil–landscape–vegetation relationships and, specifically, the ecophysiology of plant communities developing on sandy soils of very low fertility that are subject to seasonal flooding. It provides an overview of the white sand ecosystems within the Amazon basin, and focuses on the forest and herbaceous (meadows) vegetation growing on the dystrophic sandy soils of the upper Negro and Orinoco river basins. Several chapters describe physiographic aspects of the study area using integrated remote sensing and in situ sampling. By doing so they attain a comprehensive description of the origin and evolution of soils and landscapes, an advanced classification of soils, and a mapping of the geographic distribution of psammophilous vegetation. This volume also provides a phytosociological classification of extensive forested areas, and a detailed description of the structure and diversity of little-known herbaceous formations. It targets professionals in the fields of ecology, ecophysiology, geomorphology, soils, vegetation, and the environmental sciences. The information it offers may be of significant use to researchers, protected area planners, and environmental policy makers.
    Type of Medium: Online Resource
    Pages: XIV, 541 p. 136 illus., 122 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031207990
    Series Statement: Ecological Studies, Analysis and Synthesis, 247
    URL: https://doi.org/10.1007/978-3-031-20799-0
    DOI: 10.1007/978-3-031-20799-0
    DDC: 577
    Language: English
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  • 6
    Online Resource
    Online Resource
    Sustainable Utilization and Conservation of Africa’s Biological Resources and Environment (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Biodiversity. ; Biotic communities. ; Population biology. ; Agricultural ecology. ; Ecology. ; Biodiversity. ; Community and Population Ecology. ; Agroecology.
    Description / Table of Contents: Chapter 1. Overview of African Biological Resources and Environment -- Chapter 2. Biodiversity Conservation and Tourism Sustainability in Africa -- Chapter 3. Biodiversity Conservation Strategies and Sustainability -- Chapter 4. Potentials, threats, and sustainable conservation strategies of Plankton and Macrophytes -- Chapter 5. Threats and conservation status of cercopithecus sclateri in Akwa Ibom State, Nigeria -- Chapter 6. Potential threats and possible conservation strategies of Biodiversity in Niger Delta region of Nigeria -- Chapter 7. Exploration of Local Beliefs and Cultural Heritages as Tools for Species Conservation in Selected Sites in Africa -- Chapter 8. The need to conserve and protect forest resources -- Chapter 9. Rationale behind conservation of Africa’s biological resources -- Chapter 10. The Value of Biodiversity to Sustainable Development in Africa -- Chapter 11. Medicinal potentials of Aloe vera (Aloe barbadensis Miller): Technologies for the production of Therapeutics -- Chapter 12. Sustainable utilization of important medicinal plants in Africa -- Chapter 13. Local Food Crops In Africa: Sustainable Utilization, Threats, And Traditional Storage Strategies -- Chapter 14. Environmental Pollution: Threats, Impact on Biodiversity, and Protection Strategies -- Chapter 15. Environmental Degradation in the Niger Delta Ecosystem: the role of Anthropogenic pollution -- Chapter 16. Climate Change and Other Environmental Factors as Drivers of Fauna and Flora Biodiversity in Africa -- Chapter 17. Contamination of African water resources: impacts on biodiversity and strategies for conservation and restoration -- Chapter 18. Disease Outbreaks In Ex-Situ Plant Conservation And Potential Management Strategies -- Chapter 19. Challenges of sea turtle conservation in African territorial waters: the way out -- Chapter 20. An Overview of Environmental Resources in Africa: Emerging Issues and Sustainable Exploitation -- Chapter 21. Touristic Value of African Environment: A Socio-Economic Perspective. Chapter 22. Environmental Sustainability: Relevance of Forensic Insects and other Ecosystem Services in Africa -- Chapter 23. Intrinsic Values of the African Environment: A Sustainable Perspective -- Chapter 24. Towards sustainable biological and environmental policies in Africa.
    Abstract: This edited book highlights the potential and actual contributions of the sustainable management and utilization of indigenous biological resources and environment for the development of Africa. The book centers on documenting current trends and issues in the field of resource use and conservation with the view of emphasizing their benefits to the pursuit of development within the region. By documenting the array of natural resources and environment in Africa, this book addresses the topical knowledge and understanding gaps that characterize conservation (rationale for sustainable resource exploration), utilization patterns, and conservation challenges including policy status, environmental threats, impacts of tourism, reduction in food resources, etc., and their effects on the sustainable development of Africa. Through an integrated approach, the book focuses on below and above-ground biological resources and the diverse scales of environment that characterize Africa. This collection of works is very helpful for natural and social scientists, policymakers, strategists, researchers, government and non-government organizations, biodiversity and environmental managers, climate change scientists, practitioners, activists, conservationists, academics, ecologists, undergraduate and postgraduate students, and others who want to learn about and understand the best way to use and protect Africa's resources and heritage sustainably.
    Type of Medium: Online Resource
    Pages: XV, 691 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811969744
    Series Statement: Sustainable Development and Biodiversity, 32
    URL: https://doi.org/10.1007/978-981-19-6974-4
    DOI: 10.1007/978-981-19-6974-4
    DDC: 577
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cancer Neuroscience (2023)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Cancer Treatment. ; Neurosciences. ; Immunotherapy. ; Cancer Biology. ; Cancer Therapy. ; Neuroscience. ; Cancer Microenvironment. ; Immunotherapy.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Neuronal influence on cancer initiation and growth -- Chapter 2.1 Paracrine signaling in CNS primary tumors and brain metastases -- Chapter 2.2 Paracrine signaling in PNS primary tumors -- Chapter 3. Neuronal influence on cancer invasion and metastasis including perineurial invasion -- Chapter 4. Neurotrophic activity of tumors -- Chapter 5. Cancer interactions with Schwann cells -- Chapter 6. Cancer-glial interactions -- Chapter 7. Neuron-cancer synaptic and other electrical signaling -- Chapter 8. Neuro-immune interactions system and immuno-oncology -- Chapter 9. Nervous system interactions with non-immune elements in the cancer microenvironment -- Chapter 10. Cancer-induced remodeling of the nervous system -- Chapter 11. Cancer and pain -- Chapter 12. Systemic interactions of cancer and the impact on the nervous system -- Chapter 13. Tools and model systems to study nerve-cancer interactions -- Chapter 14. Conclusions and Future Directions.
    Abstract: This volume is the first on the market to address and discuss the emerging field of cancer neuroscience. Edited by pioneers in the field with contributions from top researchers, the volume serves as a comprehensive overview of the role of nerves in tumorigenesis and cancer progression. Chapters will address how the innervation of tumors can serve as both prognostic and predictive biomarkers as well as actionable therapeutic targets. Authors will describe current research efforts, and future directions for study and translation to the clinic. It is becoming increasingly apparent that certain treatments will need to consider interactions between the nervous system and cancer, and the novel concepts presented in the book address related accumulating evidence regarding therapeutic strategies. This unique volume will be useful for cancer researchers, neuroscientists, cancer biologists, oncologists, and others looking to gain a greater understanding of this emerging field.
    Type of Medium: Online Resource
    Pages: XII, 202 p. 21 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031324291
    URL: https://doi.org/10.1007/978-3-031-32429-1
    DOI: 10.1007/978-3-031-32429-1
    DDC: 571.978
    Language: English
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  • 8
    Online Resource
    Online Resource
    Hepatobiliary Cancers: An Interdisciplinary Approach (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Cancer. ; Cancer Treatment. ; Tumors Immunological aspects. ; Immunotherapy. ; Cancer Genetic aspects. ; Stem cells. ; Cancer Biology. ; Cancer Therapy. ; Tumour Immunology. ; Immunotherapy. ; Cancer Genetics and Genomics. ; Cancer Stem Cells.
    Description / Table of Contents: Interdisciplinary Approach in Hepatobiliary Cancers -- Liver Cancer: Interdisciplinary Approach -- The Immune System in Liver Cancer: From Beginning to Progression -- The Tumor Microenvironment in Hepatocellular Carcinoma -- Metabolic Alterations of Hepatocellular Cancer Stem Cells -- Τhe Role of Senescence in NASH-related HCC -- Regulators of Genetic Risk for the Progression of Non-alcoholic Fatty Liver Disease to Hepatocellular Carcinoma: Reconstruction of Transcriptional Network and Signature-Based Metabolic Profiling -- Tumor Microenvironment and Immunotherapy in Advanced Biliary Tract Cancers -- Fibrosis and Immunotherapy in Hepatocellular Carcinoma -- Liver Cancer and the Curative Potential of Nanomedicine -- Locoregional Therapies for Hepatocellular Carcinoma -- Drug Resistance in Hepatocellular Carcinoma -- Liver Stereotactic Body Radiotherapy.
    Abstract: Hepatobiliary cancers, including hepatocellular carcinoma and biliary tract cancers, have high rate of mortality and low survival rate. The third volume of the “Interdisciplinary Cancer Research” series, entitled “Hepatobiliary Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of hepatobiliary cancers and therapeutic modalities and presents the most updated and peer-reviewed chapters on hepatobiliary cancers. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on hepatobiliary cancers.
    Type of Medium: Online Resource
    Pages: XI, 365 p. 22 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031445286
    Series Statement: Interdisciplinary Cancer Research, 3
    URL: https://doi.org/10.1007/978-3-031-44528-6
    DOI: 10.1007/978-3-031-44528-6
    DDC: 571.978
    Language: English
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  • 9
    Online Resource
    Online Resource
    Gastrointestinal Cancers: An Interdisciplinary Approach (2023)
    Cham :Springer Nature Switzerland :
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    Keywords: Cancer. ; Cancer Treatment. ; Oncology. ; Immunotherapy. ; Tumors Immunological aspects. ; Nanomedicine. ; Cancer Biology. ; Cancer Therapy. ; Oncology. ; Immunotherapy. ; Tumour Immunology. ; Cancer Nanotechnology.
    Description / Table of Contents: Interdisciplinary Approach in Gastrointestinal Cancers -- Gastrointestinal Cancers: What Is the Real Board of Microenvironment and the Role of Microbiota-Immunity Axis -- Epithelial-Mesenchymal Transition in Gastrointestinal Cancer: From a Basic to a Clinical Approach -- Metabolomics of Gastrointestinal Cancers -- Deregulation of Immune System in Gastric Cancer Development, How Immune Nutrition Might Restore the Functions of Immune Cells -- Helicobacter pylori Virulence Factors, Pathogenicity, and Gastric Cancer -- Gastric Cancer and Helicobacter pylori -- Role of Neuromodulators in Regulation of the Tumor Microenvironment of Gastric and Colorectal Cancers -- The Role of Tumor Microenvironment in Colon Cancer -- Unraveling the Esophageal Cancer Tumor Microenvironment: Insights and Novel Immunotherapeutic Strategies -- The Interplay Between Immunity and Gut Microbiota in Colon Cancer -- Immunotherapy in Gastrointestinal Cancer Focusing on CAR-T Cell Therapy -- Development of Biocompatible Nanocarriers for the Treatment of Colorectal Cancer -- Challenges of Onco-therapeutics in Early Onset Colorectal Cancer -- Unintentional Weight Loss and Malnutrition After Esophageal Cancer and Treatment -- Current Clinical Landscape of Immunotherapeutic Approaches in Pancreatic Cancer Treatment. The Tumor Microenvironment in Pancreatic Cancer and Challenges to Immunotherapy. .
    Abstract: Gastrointestinal cancers are among the most prevalent malignancies worldwide, with high rate of global cancer incidence and cancer-related death. Gastrointestinal cancers include esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and liver cancer, which all, except the last one, are covered in this volume. The fourth volume of the “Interdisciplinary Cancer Research” series, entitled “Gastrointestinal Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of gastrointestinal cancers and novel immunotherapy opportunities and presents the most updated and peer-reviewed chapters on gastrointestinal cancers therapy. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on gastrointestinal cancers.
    Type of Medium: Online Resource
    Pages: XI, 404 p. 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031483714
    Series Statement: Interdisciplinary Cancer Research, 4
    URL: https://doi.org/10.1007/978-3-031-48371-4
    DOI: 10.1007/978-3-031-48371-4
    DDC: 571.978
    Language: English
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  • 10
    Online Resource
    Online Resource
    Movement Ecology of Afrotropical Forest Mammals (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Vertebrates. ; Animal behavior. ; Population biology. ; Ecology. ; Vertebrate Zoology. ; Behavioral Ecology. ; Population Dynamics.
    Description / Table of Contents: 1. What do we know about mammal movement in African tropical forests? -- 2. Movements patterns and population dynamics of giant forest hog groups in Kibale National Park, Uganda -- 3. Forest elephant movements in Central Africa – megafauna need megaspaces -- 4. Elephant movements, abundance and use of water sources in Kibale National Park, Uganda -- 5. Movement ecology and evolutionary history of forest buffalo -- 6. Site fidelity and home range shifts in a leaf-eating primate -- 7. Primate movements across the nutritional landscapes of Africa -- 8. Conditions facilitating a “landscape of fear from disease” in African forest mammals -- 9. Do seasonally frugivory and cognition shape foraging movements in wild western gorillas? -- 10. Females Move in Tight Crowds, Males Roam: Society and Movement Ecology of Mandrills -- 11. Linking Movement Ecology to Conservation Biology.
    Abstract: This book brings a unique perspective to animal movement studies because all studies come from African tropical environments where the great diversity, either biological and structurally (trees, shrubs, vines, epiphytes), present the animals with several options to fulfil their basic needs. These conditions have forced the evolution of unique movement patterns and ecological strategies. The book follows on our previous book “Movement Ecology of Neotropical Forest Mammals” but focuses on tropical African forests. Movement is an essential process in the life of all organisms. Animals move because they are looking for primary needs such as food, water, cover, mating and to avoid predators. Understanding the causes and consequences of animal movement is not an easy task for behavioural ecologists. Many animals are shy, move in secretive ways and are very sensible to human presence, therefore, studying the movements of mammals in tropical environments presents logistical and methodological challenges. However, researchers have recently started to be solved these challenges and exciting new information is emerging. In this book we are compiling a set of extraordinary studies where researchers have used new technology and the strongest methodological approaches to understand movement patterns in wild African forest mammals. This second book should inspire early career researchers to investigate wild mammal´s movements in some of the most amazing forest in the world: African tropical forests. .
    Type of Medium: Online Resource
    Pages: XVII, 196 p. 42 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031270307
    URL: https://doi.org/10.1007/978-3-031-27030-7
    DOI: 10.1007/978-3-031-27030-7
    DDC: 577
    Language: English
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  • 11
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    Online Resource
    Artificial Intelligence and Precision Oncology : Bridging Cancer Research and Clinical Decision Support (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Cancer. ; Oncology. ; Medical screening. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Oncology. ; Cancer Screening. ; Cancer Therapy. ; Tumour Biomarkers.
    Description / Table of Contents: Chapter 1. Introduction: The Application of AI in Precision Oncology: Tailoring Diagnosis, Treatment, and the Monitoring of Disease Progression to the Patient -- Part I. Artificial Intelligence for Screening, Diagnosis, Monitoring in Precision Oncology -- Chapter 2. Application of AI in Novel Biomarkers Detection that Induce Drug Resistance, Enhance Treatment Regimens and Advancing Precision Oncology -- Chapter 3. Use of Artificial Intelligence in Implementing Mainstream Precision Medicine to Improve Traditional Symptom-driven Practice of Medicine: Allowing Early Interventions and Tailoring better-personalized Cancer Treatments -- Chapter 4. AI as a Novel Approach for Exploring ccfNAs in Personalized Clinical Diagnosis and Prognosis: Providing Insight into the Decision-Making in Precision Oncology -- Chapter 5. AI-Enhanced Digital Pathology and Radiogenomics in Precision Oncology -- Part II. Artificial Intelligence and Omics in Precision Oncology -- Chapter 6. Epigenetics Analysis Using Artificial Intelligence in the Era of Precision Oncology -- Chapter 7. Association of Metabolomics with AI in Precision Oncology: Emerging Perspectives for More Effective Cancer Care -- Chapter 8. Artificial Intelligence Application to Microbiomics Data for Improved Clinical Decision Making in Precision Oncology -- Part III. Artificial Intelligence in Cancer Therapy and the Clinical Applications -- Chapter 9. AI and Nanotechnology in Realizing the Goal of Precision Medicine: Tailoring the Best Treatment for Personalized Cancer Treatment -- Chapter 10. Artificial Intelligence-Based Medical Devices Revolution in Cancer Screening: Impact into Clinical Practice -- Chapter 11. Intelligent Drug Design and Use for Cancer Treatment: The Roles of AI and Precision Oncology in Targeting Patient-Specific Splicing Profiles -- Chapter 12. Applying Artificial Intelligence Prediction Tools for Advancing Precision Oncology in Immunotherapy: Future Perspectives in Personalized Care -- Chapter 13. Employing AI-Powered Decision Support Systems in Recommending the Most Effective Therapeutic Approaches for Individual Cancer Patients: Maximizing Therapeutic Efficacy -- Chapter 14. AI-Pathway Companion in Clinical Decision Support: Enabling Personalized and Standardized Care Along Care Pathways in Oncology -- Chapter 15. AI Tools Offering Cancer Clinical Applications for Risk Predictor, Early Detection, Diagnosis, and Accurate Prognosis: Perspectives in Personalised Care -- Chapter 16. Conclusion and Insights into the Future of AI in Precision Oncology.
    Abstract: This book highlights the use of artificial intelligence (AI), big data and precision oncology for medical decision making in cancer screening, diagnosis, prognosis and treatment. Precision oncology has long been thought of as ideal for the management and treatment of cancer. This strategy promises to revolutionize the treatment, control, and prevention of cancer by tailoring tests, treatments and predictions to specific individuals or population groups. In order to accomplish these goals, vast amounts of patient or population group specific data needs to be integrated and analysed to be able to identify key patterns or features which can be used to define or characterize the disease or the response to the disease in these individuals. These patterns or features can be as varied as molecular patterns or features in medical images. This level of data analysis and integration can only be achieved through the use of AI. The book is divided into three parts starting with a section on the use of artificial intelligence for screening, diagnosis and monitoring in precision oncology. The second part: Artificial intelligence and Omics in precision oncology, highlights the use of AI and epigenetics, metabolomics, microbiomics in precision oncology. The third part covers artificial intelligence in cancer therapy and its clinical applications. It also highlights the use of AI tools for risk prediction, early detection, diagnosis and accurate prognosis. This book, written by experts in the field from academia and industry, will appeal to cancer researchers, clinical oncologists, pathologists, medical students, academic teaching staff and medical residents interested in cancer research as well as those specialising as clinical oncologists.
    Type of Medium: Online Resource
    Pages: XIV, 315 p. 64 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031215063
    URL: https://doi.org/10.1007/978-3-031-21506-3
    DOI: 10.1007/978-3-031-21506-3
    DDC: 571.978
    Language: English
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  • 12
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    Online Resource
    Molecular Biology of Human Cancers (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Oncology. ; Cancer Biology. ; Biomedical Research. ; Oncology.
    Description / Table of Contents: Part I: Molecules, Genes, Cells and Mechanisms -- Chapter 1: An Introduction to Human Cancers -- Chapter 2: Cancer Genetics -- Chapter 3: DNA Damage and DNA Repair -- Chapter 4: Oncogenes -- Chapter 5: Tumor Suppressor Genes -- Chapter 6: Cancer Pathways -- Chapter 7: Cell Death and Replicative Senescence in Cancer -- Chapter 8: Cancer Epigenetics -- Chapter 9: Invasion and Metastasis -- Part II: Human Cancers -- Chapter 10: Leukemias And Lymphomas -- Chapter 11: Pediatric Cancers -- Chapter 12: Cancers of the Skin -- Chapter 13: Colorectal Cancer -- Chapter 14: Bladder Cancer -- Chapter 15: Lung Cancer -- Chapter 16: Renal Cell Carcinomas -- Chapter 17: Liver Cancer -- Chapter 18: Gastric Cancer -- Chapter 19: Breast Cancer -- Chapter 20: Prostate Cancer -- Part Iii: Prevention, Diagnostics and Therapy -- Chapter 21: Cancer Prevention -- Chapter 22: Cancer Diagnostics -- Chapter 23: Cancer Therapy.
    Abstract: This textbook describes the most relevant molecular and biological processes in cancer, how they contribute to the development and progression of individual cancer types in humans, and how insights from molecular cancer research can be applied to improve cancer prevention, diagnostics and treatment. Part I of the textbook summarizes the current fundamental knowledge on the general properties of cancers, the causes of cancer, cancer genetics, genomics and epigenetics. Individual chapters address the functions of DNA damage and repair, oncogenes and tumor suppressors in carcinogenesis and discuss crucial mechanisms in cancer pathogenesis, such as apoptosis and replicative senescence, as well as the most relevant signal transduction pathways and regulatory networks. Part I concludes with a chapter on tumor invasion and metastasis and tumor immunology. In Part II, the most relevant mechanisms acting in individual human cancers (and subtypes) are described in more detail. This central part of the book contains individual sections on the most common human cancers highlighting the diversity in their genetic, molecular and cellular pathogenic mechanisms. How insights from molecular cancer research are translated into improvements in prevention, diagnosis, and treatment is outlined in Part III. This new edition has been extensively revised and includes in particular updated information on cancer genomics, epigenetics, viral carcinogenesis, cancer diagnostics and cancer therapy and a new chapter on lung cancers. Now more than ever, cancer research is an interdisciplinary endeavor that requires a basic knowledge of commonly used terms, facts and concepts. The aim of this book is to provide advanced students and practitioners in various disciplines with this foundation, bridging the gap between standard textbooks of molecular biology, pathology and oncology on the one hand and the specialized cancer literature on the other.
    Type of Medium: Online Resource
    Pages: XXI, 542 p. 229 illus., 221 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031162862
    URL: https://doi.org/10.1007/978-3-031-16286-2
    DOI: 10.1007/978-3-031-16286-2
    DDC: 571.978
    Language: English
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  • 13
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    Online Resource
    Therapeutic potential of Cell Cycle Kinases in Breast Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Cancer Treatment. ; Cancer Genetic aspects. ; Cancers. ; Cancer Therapy. ; Cancer Genetics and Genomics.
    Description / Table of Contents: Chapter 1 An introduction to breast cancer -- Chapter 2 Current treatment approaches to breast cancer. Chapter 3 Introduction to cell cycle and its regulators -- Chapter 4 Cell cycle and cancer -- Chapter 5 cell cycle dysregulation in breast cancer -- Chapter 6 Molecular Subtypes of breast cancer and CDK dysregulation -- Chapter 7 Breast tumor micro environment and CDks -- Chapter 8 CDK Dysregulation in Breast Cancer: A Bioinformatics Analysis -- Chapter 9 CDK1 Dysregulation in Breast Cancer -- Chapter 10 CDK4/CDK6 dysregulation in estrogen positive receptor breast cancers -- Chapter 11 Therapeutic implications of CDKs in Breast Cancer -- Chapter 12 Novel CDK Inhibitors in Breast Cancer -- Chapter 13 Targeting CDKs with other chemotherapeutic drugs- A combinatorial approach -- Chapter 14 CDKs in cell-cycle progression and therapeutic strategies in Human breast cancer -- Chapter 15 CDk inhibitor for treatment of breast cancer -- Chapter 16 Response of therapy in cell cycle regulatory genes in breast cancer -- Chapter 17 Different cyclins and their significance in Breast cancer.
    Abstract: This book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints and dysregulation in breast cancer. It also examines the prognostic significance of CDKs in breast cancer. and CDK inhibitors for the treatment of metastatic breast cancer. Further, the book discusses the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. Additionally, it examines the role of immunogenic effects of CDK inhibitors, the mechanism of resistance and the current clinical trials in breast cancer treatment. Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. This book is a comprehensive yet concise resource for oncologists and researchers interested in exploring the therapeutic potential of Cyclin-Dependent Kinases in breast cancer.
    Type of Medium: Online Resource
    Pages: XVII, 373 p. 133 illus., 92 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811989117
    URL: https://doi.org/10.1007/978-981-19-8911-7
    DOI: 10.1007/978-981-19-8911-7
    DDC: 571.978
    Language: English
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  • 14
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    Online Resource
    Ecology of Angola : Terrestrial Biomes and Ecoregions (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Biodiversity. ; Conservation biology. ; Environmental management. ; Environmental geography. ; Ecology. ; Terrestial Ecology. ; Biodiversity. ; Conservation Biology. ; Environmental Management. ; Integrated Geography.
    Description / Table of Contents: Introduction -- Biomes: Concepts, Characteristics and Terminology -- Profiles of Angola’s Biomes and Ecoregiens -- Landscapes: Geology, Hydrology and Geomorphology.
    Abstract: This open access book richly illustrates the first, and comprehensive, account of the country’s biomes and ecoregions, the driving forces that account for their diversity and vulnerability, and the ecological principles that provide an understanding of the patterns and processes that have shaped landscapes, ecoregions, and ecosystems. Angola encompasses the greatest diversity of terrestrial biomes and is the second richest in terms of ecoregions, of any African country. Yet its biodiversity and the structure and functioning of its ecosystems are largely undocumented. The author draws on personal field observations from over 50 years of involvement in ecological and conservation studies in Angola and across Southern Africa. The vast recent literature published by researchers in neighboring, better resourced countries provides depth to the accounts of ecological principles and processes relevant to Angola and thus contributing to the understanding and sustainable management of its natural resources. .
    Type of Medium: Online Resource
    Pages: XIX, 459 p. 220 illus., 170 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031189234
    URL: https://doi.org/10.1007/978-3-031-18923-4
    DOI: 10.1007/978-3-031-18923-4
    DDC: 577
    Language: English
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  • 15
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    Online Resource
    Aquaculture Ecology (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Ecology . ; Vertebrates. ; Ecology. ; Vertebrate Zoology.
    Description / Table of Contents: Introduction -- Aquaculture ecosystems -- Productivity and carrying capacity of aquaculture waters -- Interactions between aquaculture and environment -- Growth of aquaculture animals -- Effects of cyclical fluctuation of environmental factors on aquatic organisms -- Biological control of water quality in aquaculture -- Sediment and remediation of aquaculture ponds -- Integrated aquaculture and their structure optimization -- Land based intensive aquaculture -- Pond aquaculture in waterlogged salt-alkali land -- Fish cage farming in open waters -- Health maintenance and welfare of aquaculture animals -- Sustainability of aquaculture production systems.
    Abstract: This book introduces aquaculture ecology as a science of the interaction between commercial aquatic organisms as well as their farming activities and the environment, including the rationales of building and management of aquaculture systems. This book covers productivity and carrying capacity, effects of cyclical fluctuation of environmental factors on aquatic organisms, biological control of water quality, structural optimization of aquaculture systems and ecological prevention of disease. In the last chapter, aquaculture production systems are introduced from multiple perspectives. This book has been designed to provide a stimulating and informative text for researchers in aquaculture, fisheries as well as hydrobiology.
    Type of Medium: Online Resource
    Pages: XVII, 573 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811954863
    URL: https://doi.org/10.1007/978-981-19-5486-3
    DOI: 10.1007/978-981-19-5486-3
    DDC: 577
    Language: English
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  • 16
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    Online Resource
    Climate Change and Urban Environment Sustainability (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Urban ecology (Biology). ; Biotic communities. ; Ecology. ; Urban Ecology. ; Ecosystems.
    Description / Table of Contents: Chapter 1Climate Change and Urban Environment Sustainability: Issues and Challenges -- Chapter 2 Infrastructure, Energy Needs and Waste Management for Sustainable Urban Regions -- Chapter 3 Climate Change and Sustainable Urban Transport Environment -- Chapter 4 Importance of Climatological Inputs in the Green Infrastructure Design, Sustainable City Planning towards Better Urban Settlement -- Chapter 5 Methodology for Sustainable Urban Planning -- Chapter 6 Exploring Sustainable Food Systems for Urban Sustainability -- Chapter 7 Seagrasses in the Indian ocean region with special reference to urbanization -- Chapter 8 Water Quality Index: An Important Tool to Access Water Quality for Sustainable Development -- Chapter 9 Urbanization trends, Climate change and Environmental sustainability -- Chapter 10 Novel Technologies and Eco-friendly Lifestyle for Sustainable Cities -- Chapter 11 Spatial Analysis of Precipitation Climatology over India: Using satellite Remote Sensor -- Chapter 12 Timberline and Climate in the Indian Western Himalayan Region: Changes and Impact on Timberline Elevations -- Chapter 13 Design of Humanitarian Logistics Network Using Imperialist Competitive Algorithm -- Chapter 14 Impact of Climate Change Related Heat Stress on Thermophysiological Vulnerability Among Workers in Unorganized Sectors -- Chapter 15 Seagrass of Southeast Asia: Challenges, Prospects, and Management Strategies -- Chapter 16 Effect of Climate Change and Urbanization on Mangrove Ecosystems -- Chapter 17 Urbanization and climate change impact on habitat destruction and zoonotic species emergence -- Chapter 18 Roles of Community Resilience and Risk appraisal in climate change adaptation.
    Abstract: This book covers the understanding on relationship between climate change, urban development, and environment sustainability with emphasis on relevant issues and challenges of urban environment sustainability. It deals with the concept of climate resilient urban development, effective implementation of climate change adaptation and mitigation actions to promote urbanization from a social, economic, and environmental perspective. Climate change is a critical issue and having serious concern. Understanding the mechanism of climate change and climate variability is an important aspect and requires monitoring in their regional perspectives. Smart and resilient urbanization are essential in tackling the growing threat of climate instability. Different analytical and practical approaches to foster resilience and environmental sustainability in urban areas covering the recent trends, developments and tools related to urban environment, sustainability, and climate change. There is a big demand of understanding on the relationship between climate change, urban environment sustainability due to fast urbanization and an urgent need for constructive and effective mechanism to protect the life and property of human being from expected or anticipated hazards and disasters. This book is of interest and useful to academicians, researchers, scientists, environmentalists, land resource managers, climate change scientists, forest administrators. Also, the book serves as a reference to researchers and students of agriculture, forestry, ecology, soil science, and environmental sciences. Policy makers will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XIII, 329 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811976186
    Series Statement: Disaster Resilience and Green Growth,
    URL: https://doi.org/10.1007/978-981-19-7618-6
    DOI: 10.1007/978-981-19-7618-6
    DDC: 577
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  • 17
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    Sustainable Squirrel Conservation : A Modern Reassessment of Family Sciuridae (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Animal culture. ; Sustainability. ; Geographic information systems. ; Environment. ; Ecology. ; Animal Science. ; Sustainability. ; Geographical Information System. ; Environmental Sciences.
    Description / Table of Contents: Part 1: Introduction to squirrels of the world and their conservation trends. Chapter 1: The World’s Squirrel Taxonomy -- Chapter 2: Evolution, habitat trends, and extinction rate estimates of the world squirrels -- Part 2: Squirrels of the world in the Anthropocene. Chapter 3: Habitat Trends and the Squirrel-Human Interface -- Chapter 4: A Meta-analysis based on Open Access Big Data Mining of Global Predicted Squirrel Distribution Models with Machine Learning for IUCN Conservation Status and Trend Policy Assessments -- Chapter 5: Squirrels in Cities -- Chapter : Squirrels in the Tropics -- Chapter 7: Squirrels on Islands -- Chapter 8: Tree squirrels in old-growth forests? -- Chapter 9: Can squirrels be used as indicators to identify and protect old-growth forest reserves? -- Chapter 10: Squirrel Economics -- Part 3: Problems and governance in the squirrel world. Chapter 11: Squirrel Hunting Regulations and Enforcement (Or Lack Thereof) -- Chapter 12: Where do the World’s Squirrel Hotspots and Coldspots of 230+ species go with Climate change 2100? -- Chapter 13: Squirrel’s marginalization and modern lack of conservation and poor sustainability outlook as a call to good action -- Part 4: First conclusions and the way forward. Chapter 14: A Conservation Management SWOT analysis for over 300 Squirrels of the World using 132 GIS layers confirming the PESTLE assessment -- Chapter 15: First Conclusions, Success stories, and Calls-to-action for the conservation of the world’s squirrels.
    Abstract: This book attempts to move the family of squirrels (Sciuridae) out of the shadow of large charismatic mammals and to highlight management failures with the goal of moving towards an improved conservation approach. Particular attention is paid to the influence of taxonomic science on squirrel conservation. In addition, the authors show how human-driven climate change, global change and modern politics are shaping global squirrel populations as well as their surrounding environments and ecosystems. Squirrels are widespread around the globe, naturally occurring on every continent except Antarctica and Oceania, and they are certainly among the animals most commonly encountered in everyday life. Despite this, the authors of this volume identify worrying gaps in squirrel conservation. Squirrels are often hunted, trapped, poached, and stressed, and management strategies and legislation are often devised in the absence of proper knowledge of issues such as population sizes, taxonomies, and trends. Together, this can result in severe population declines and even species extinction. By assessing their taxonomic situation, ecology, the evolution and divergence of Sciuridae around the globe, and squirrels’ well-being across habitats, the authors set a baseline from which to launch future investigations into the conservation of squirrels and other species. Additionally, the authors highlight the influences of climate change, unsustainable growth, and various man-made threats to the future of this family.
    Type of Medium: Online Resource
    Pages: XVII, 380 p. 228 illus., 221 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031235474
    URL: https://doi.org/10.1007/978-3-031-23547-4
    DOI: 10.1007/978-3-031-23547-4
    DDC: 577
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  • 18
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    Oncology: Genomics, Precision Medicine and Therapeutic Targets (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Cancer Genetic aspects. ; Oncology. ; Therapeutics. ; Cancer Biology. ; Cancer Genetics and Genomics. ; Oncology. ; Therapeutics.
    Description / Table of Contents: Chapter 1 Evolution of translational cancer therapeutics -- Chapter 2 Oncology: Way forward from clinical and molecular diagnosis to treatment -- Chapter 3 Oncogenic genomics alterations in cancer patient -- Chapter 4 Altered mRNA expression profiles in cancer patients -- Chapter 5 microRNAs and long non-coding RNAs as key targets -- Chapter 6 Oncogenic alterations translated into diagnostics -- Chapter 7 Precision medicine in oncology -- Chapter 8 Precision medicine – translation of individualistic treatment in oncology -- Chapter 9Pharmacogenetics and Pharmacogenomics in Precision Medicine -- Chapter 10 Pharmacogenetic factors in pharmacodynamic/pharmacokinetic (PD/PK) modulations of medicines -- Chapter 11 Biomarkers in Precision Medicine in oncology -- Chapter 12 Bioinformatics and biostatistics in Precision Medicine -- Chapter 13 Omics in Precision medicine -- Chapter 14 Translational therapeutic targets : from bench to clinical trials -- Chapter 15 Strength of integartive genomic alterations, precision medicine and therapeutic targets as treatment choice in patient care.
    Abstract: This book describes translational cancer therapeutics and the way forward from clinical and molecular diagnosis to treatment. In addition, genomics alterations, microRNAs, and long non-coding RNAs translate precision medicine for the individualistic therapy of cancer patients. It describes the involvement of various pharmacogenetic factors in pharmacodynamic/pharmacokinetic (PD/PK) modulations of medicines. Indeed, the role of bioinformatics and biostatistics, considering the extensive data analysis serving precision medicine approaches, has also been entertained in the present book. Therefore, intended book demonstrates the successful medical evidence for the use of precision medicine in the treatment of cancer and its future clinical perspectives. It fills the gaps in cancer biology and precision medicine with its up-to-date content and well-designed chapters. It will serve as a valuable resource for science, medical students, and interdisciplinary researchers. It is a very welcome addition for the scientific community, research centers, and university-industry research collaborators to find out a complete capsular package about cancer drug targets, precision, and personalized medicine (including an introduction to cancer cell signaling, genomic alterations, miRNA targeting, pharmacogenetics, biomarkers, and metabolomics in precision medicine, etc.) at a single platform.
    Type of Medium: Online Resource
    Pages: XVI, 274 p. 23 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819915293
    URL: https://doi.org/10.1007/978-981-99-1529-3
    DOI: 10.1007/978-981-99-1529-3
    DDC: 571.978
    Language: English
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  • 19
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    Online Resource
    Cancer Research: An Interdisciplinary Approach (2023)
    Cham :Springer Nature Switzerland :
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    Keywords: Cancer. ; Cancer Treatment. ; Stem cells. ; Cytology. ; Medical genetics. ; Immunology. ; Cancer Biology. ; Cancer Therapy. ; Cancer Stem Cells. ; Cell Biology. ; Medical Genetics. ; Immunology.
    Description / Table of Contents: Interdisciplinary Approaches in Cancer Research -- Role of Immune Cells in the Tumor Microenvironment -- Spatial Transcriptomic Approaches for Understanding the Tumor Microenvironment (TME) -- Role of Mesenchymal Stem/Stromal Cells in Cancer Development -- Cancer-associated Fibroblasts and Their Role in Cancer Progression -- The Role of Tumoroids in Cancer Research -- Myokines Expression in Cancer Cachexia -- Epigenetics in Cancer Biology -- Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation -- Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity -- Molecular Mechanisms of Metal-induced Carcinogenesis -- Epi-drugs Targeting RNA Dynamics in Cancer -- Oncologic Emergencies: Pathophysiology, Diagnosis, and Initial Management -- Malignancies in Inborn Errors of Immunity -- Hematopoietic Stem Cell Transplantation in Patients with Inborn Errors of Immunity and Malignancy -- Personalized Immuno-oncology with Immunodeficiency Mouse Models -- Allergy and Cancer: New Perspectives -- Depression and Cancer: the Inflammatory Bridge -- Impact of Cancer-Related Sarcopenia on Systemic Immune Status -- Surveillance of Subclinical Cardiovascular Complications in Childhood Cancer Survivors: Exercise as a Diagnostic and Therapeutic Modality.
    Abstract: Cancer is a major public health concern and one of the leading causes of death. There is no simple solution for this complex disease, therefore interdisciplinary approaches might help to find solutions to many unanswered questions and challenges about cancer. The rapid flow of interdisciplinary research in cancer during recent years has increased our understanding of the nature of cancers. Such interdisciplinary approaches could be helpful for both the diagnosis and the development of more effective therapeutic strategies. The “Interdisciplinary Cancer Research” series publishes comprehensive volumes on different cancers and presents the most updated and peer-reviewed articles on human cancers. Over the past decade, increased cancer research has greatly improved our understanding of the nature of cancerous cells which has led to the development of more effective therapeutic strategies to treat cancers. This interdisciplinary series is of special value to researchers and practitioners working on cell biology, immunology, hematology, biochemistry, genetics, oncology and related fields. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN).
    Type of Medium: Online Resource
    Pages: XI, 611 p. 31 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031324581
    Series Statement: Interdisciplinary Cancer Research, 1
    URL: https://doi.org/10.1007/978-3-031-32458-1
    DOI: 10.1007/978-3-031-32458-1
    DDC: 571.978
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  • 20
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    Online Resource
    Rangeland Wildlife Ecology and Conservation (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Conservation biology. ; Zoology. ; Animal culture. ; Biotic communities. ; Freshwater ecology. ; Marine ecology. ; Ecology. ; Conservation Biology. ; Zoology. ; Animal Science. ; Ecosystems. ; Freshwater and Marine Ecology.
    Description / Table of Contents: 1. Introduction to Rangeland Wildlife Ecology and Conservation -- Part I Rangeland Ecosystems and Processes -- 2. Rangelands of Western North America -- 3. A History of North American Rangelands -- 4. Western Rangeland Livestock Production Systems and Grazing Management -- 5. Manipulation of Rangeland Wildlife Habitats -- 6. Role and Management of Fire in Rangelands -- 7. Water is Life: Importance and Management of Riparian Areas for Rangeland Wildlife -- 8. Rangeland Biodiversity -- Part II Species Accounts -- 9. Prairie Grouse -- 10. Sage-Grouse -- 11. Quails -- 12. Rangeland Songbirds -- 13. Wetland Birds of Rangelands -- 14. Avian Predators in Rangelands -- 15. Burrowing Rodents -- 16. Mesocarnivores of Western Rangelands -- 17. Black-tailed and Mule Deer -- 18. White-tailed Deer -- 19. Pronghorn -- 20. Elk -- 21. Feral Equids -- 22. Mountain Ungulates -- 23. American Bison -- 24. Large Carnivores -- 25. Amphibians and Reptiles -- 26. Insects in Grassland Ecosystems -- Part III Social-Ecological Considerations -- 27. Wildlife, Rural Communities, and the Rangeland Livelihoods they Share: Opportunities in a Diverse Economies Approach -- 28. Living with Predators: A 20-year Case Study in the Blackfoot River Watershed of Montana -- 29. A Perspective on Rangeland and Wildlife Disciplines: Similarities Over Differences -- 30. Future of Rangeland Wildlife in North America.
    Abstract: This open access book reviews the importance of ecological functioning within rangelands considering the complex inter-relationships of production agriculture, ecosystem services, biodiversity, and wildlife habitat. More than half of all lands worldwide, and up to 70% of the western USA, are classified as rangelands—uncultivated lands that often support grazing by domestic livestock. The rangelands of North America provide a vast array of goods and services, including significant economic benefit to local communities, while providing critical habitat for hundreds of species of fish and wildlife. This book provides compendium of recent data and synthesis from more than 100 experts in wildlife and rangeland ecology in Western North America. It provides a current and in-depth synthesis of knowledge related to wildlife ecology in rangeland ecosystems, and the tools used to manage them, to serve current and future wildlife biologists and rangeland managers in the working landscapes of the West. The book also identifies information gaps and serves as a jumping-off point for future research of wildlife in rangeland ecosystems. While the content focuses on wildlife ecology and management in rangelands of Western North America, the material has important implications for rangeland ecosystems worldwide.
    Type of Medium: Online Resource
    Pages: XI, 1023 p. 111 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031340376
    URL: https://doi.org/10.1007/978-3-031-34037-6
    DOI: 10.1007/978-3-031-34037-6
    DDC: 577
    Language: English
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    Online Resource
    Online Resource
    How to Fulfil the UN Sustainability Goals : Rethinking the Role and Concept of Money in the Light of Sustainability (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Sustainability. ; Energy policy. ; Energy and state. ; Schools of economics. ; Ecology. ; Sustainability. ; Energy Policy, Economics and Management. ; Heterodox Economics.
    Description / Table of Contents: Part I - Money and its role in the economy -- 1. Introduction: the world is on a collision course -- 2. What is money? -- 3. Money is like the ‘blood’ of the economy -- Part II Money and the unsustainability in stricto sensu -- 4. The growth imperative inherent in our financial system -- 5. The effect of the money interest rate on money supply, demand and growth -- 6. Economic growth in the long run is unsustainable -- 7. Economic growth or unemployment -- Part III. Money and inequality -- 8. Our current monetary system produces income inequality -- 9. Moral-ethic aspects of interest-induced inequality -- Part IV Natural money as solution -- 10. Gesell’s solution -- 11. Gesell’s Solution to achieve the SDGs -- 12. How to implement Gesell’s solution in today’s world -- 13. Alternatives to Gesell’s solution -- 14. Experiences with Gesell’s solution -- Part V Outlook and final considerations -- 15. Towards a Development at Human Scale -- 16. Economic resilience in presence of externals shocks -- 17. Final considerations.
    Abstract: This book combines the field of economics —especially monetary theory— with other disciplines like ecology, physics, humanities, social sciences and development theory. This transdisciplinary approach makes the book a unique contribution for researchers, students, policy makers and professionals working in governmental or nongovernmental institutions, as well as anyone interested in society’s well-being and achieving a true social-ecological transformation. It is written in an accessible language in order to reach a broad audience. In 2015, more than 190 world leaders recognized that the world is on a “collision course” (Max-Neef) and committed to 17 Sustainable Development Goals (SDGs). Many conferences and high-level meetings have been held since then, and one of the most frequently discussed topics is how to finance these goals. There is a widespread belief that coming up with more money for sustainable development will “do the trick”. Usually, the discussions focus on finding additional financial resources in order to achieve the goals faster. In this book it is argued that not only is more money needed, but it needs to be a different kind of money. The book demonstrates that ALL but one of the SDGs are directly linked to our monetary system, which —being completely unnatural— can be seen as the most important, but at the same time least recognized, reason for market failure. Many people think we just need to do more, faster, better. Very few say that we have done things fundamentally wrong and that the institutions and values which motivated us to do those things need to be changed. It will be concluded that only if we change our unnatural design of money to a more natural one, will we be able to reach these goals.
    Type of Medium: Online Resource
    Pages: XXV, 357 p. 54 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031377686
    URL: https://doi.org/10.1007/978-3-031-37768-6
    DOI: 10.1007/978-3-031-37768-6
    DDC: 577
    Language: English
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  • 22
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    Online Resource
    Ecosystem and Species Adaptations in the Andean-Amazonian Region : Traditional Land-Use Systems in Peru (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Biotic communities. ; Botany. ; Bioclimatology. ; Ecophysiology. ; Ecology. ; Ecosystems. ; Plant Science. ; Climate Change Ecology. ; Ecophysiology.
    Description / Table of Contents: 1- Basic concepts of ecology applied on the neotropic ecosystems -- 2 - Natural resources and sustainable development in Peru -- 3 - Classification of the Peruvian Ecosystems -- 4 - Peruvian ecosystems geography -- 5 - Biodiversity and endemism of the Andes -- 6 - Ecological communities, populations and metapopulations -- 7 - Succession and change of the ecosystems -- 8 - Biodiversity of the Amazonia Basin -- 9 - Peruvian protected natural areas -- 10 - The paramo ecosystems -- 11 - The Humboldt National Forest -- 12 - The Northwest Biosphere Reserve -- 13 - Urban ecosystems and development -- 14 - Climate changes -- 15 - Traditional land-use systems and agrobiodiversity in Peru -- Index.
    Abstract: This book focuses on ecosystems and species adaptations in the unique Peruvian Andean-Amazonian region. The presence of the Andes as the backbone is the cause of the huge ecosystem diversity and biodiversity of species that characterize the Andean-Amazonian ecosystems. The complex orography of Peru as results of the Andes presence in its tropical setting favors the occurrence of local climatic features that provide diverse environmental conditions for multiple, unique plant and animal species, many of them endemic to the Andes. The book will introduce the reader to the climatic history and geography of the Peruvian Andes and the Peruvian Natural Areas Protection system focusing on the Manu and Northwest biosphere reserves given their relevant ecological importance as well as the relationship between them and the local population. Important global topics like urbanization, deglaciation and global warming will be analyzed and discussed due to their impact in the Andes-Amazon ecosystems. Finally, the traditional land-use systems, agrobiodiversity and agrodiversity in Peru are present and linked with the climate change adaptations.
    Type of Medium: Online Resource
    Pages: XXI, 200 p. 31 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031443855
    URL: https://doi.org/10.1007/978-3-031-44385-5
    DOI: 10.1007/978-3-031-44385-5
    DDC: 577
    Language: English
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  • 23
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    Online Resource
    Microplastic sources, fate and solution (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Medicine Research. ; Biology Research. ; Biotechnology. ; Environmental engineering. ; Bioremediation. ; Environmental management. ; Ecology. ; Biomedical Research. ; Biotechnology. ; Environmental Engineering/Biotechnology. ; Environmental Management.
    Description / Table of Contents: Chapter 1. Microplastics in the freshwater and earthbound conditions: Prevalence, destinies, impacts and supportable arrangements -- Chapter 2. Effect of microplastics on microbial network -- Chapter 3.Quick estimation of microplastic in meat -- Chapter 4.Source, migration and toxicology of microplastics in soil -- Chapter 5.Impact of microplastics on nutrient -- Chapter 6.Agricultural plastic mulching as a source of microplastics in the terrestrial condition -- Chapter 7.Worldly and spatial varieties of microplastics in side of the road dust from provincial and urban area, : Implications for diffuse contamination -- Chapter 8.Microplastic particles in the Persian/Arabian Gulf -- Chapter 9.Impacts of microplastic biofilms on supplement cycling in recreated freshwater frameworks -- Chapter 10.Conveyance, bounty and dangers of microplastics in nature -- Chapter 11.Accumulation system of antibiotic medication hydrochloride from fluid arrangements by nylon microplastics -- Chapter 12.Expulsion of microplastics by means of drinking water treatment: Current information and future headings -- Chapter 13.Impacts of polystyrene microplastics on larval advancement, settlement, and transformation -- Chapter 14.Bioaccumulation of microplastics and its in vivo connections -- Chapter 15.Microplastics in oceanic situations: Toxicity to trigger biological results -- Chapter 16.Waterfront sea elements decrease the fare of microplastics to the vast sea -- Chapter 17.Barnacles as potential bioindicator of microplastic contamination in Hong Kong -- Chapter 18.Microplastic accumulation in remote ocean dregs from the Rockall Trough -- Chapter 19.Environmental microplastics: A survey on current status and points of view -- Chapter 20.The joined poisonous quality impact of microplastics and nonylphenol on microalgae Chlorella pyrenoidosa -- Chapter 21.Daylight interceded cadmium discharge from shaded microplastics containing cadmium color in watery stage -- Chapter 22.Environmental microplastic testimony in a urban environment and an assessment of transport -- Chapter 23.Biofilm modifies antibiotic medication and copper adsorption practices onto polyethylene microplastics.
    Abstract: This book provides an overview of the sources, occurrence, fate and solution of microplastics. Microplastics in sediment and soil environment have been only scarcely surveyed, and no profound discussion on microplastics removal is summarized until this book. Here we focus on sharing clear schematic information and the book sufficiently supports important microplastic topics: such as microbial network, microplastic toxicology and accumulation, agricultural plastics, nylon microplastics, polystyrene microplastics, polyethylene microplastics and many more. The book mainly provides an overview of recent advances in knowledge of sources, occurrence, distribution, chemical behavior and ecological threats while it also presents information related to feasible solutions for microplastic pollution management. This comprehensive resource will be valuable up-to-date knowledge for environmental scientists, ecotoxicologists, ecologists, marine biologists, environmental chemists in the academic field and this book is intended to be beneficial information for environmental managers, water suppliers, wastewater treatment, plastics manufacturer, and policy makers as well.
    Type of Medium: Online Resource
    Pages: XI, 129 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819906956
    URL: https://doi.org/10.1007/978-981-99-0695-6
    DOI: 10.1007/978-981-99-0695-6
    DDC: 577
    Language: English
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  • 24
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    Online Resource
    Autophagy in Stem Cell Maintenance and Differentiation (2023)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Stem cells. ; Cytology. ; Developmental biology. ; Cancer Stem Cells. ; Cell Biology. ; Developmental Biology and Stem Cells.
    Description / Table of Contents: Assays for monitoring autophagy in stem cells -- Autophagy in Stem Cell Maintenance and Differentiation -- Autophagy in Embryonic stem cells and Neural stem cells -- Autophagy in Germline Stem Cells -- The role of autophagy in the regulation of hematopoietic stem cells -- Autophagy in Muscle Stem Cells -- Autophagy in Intestinal Stem Cells -- The autophagy lysosomal pathway: friend or foe in adult neural stem cells? -- Autophagy in Mesenchymal Stem Cell-based therapy -- Autophagic control of stem cells differentiation into osteogenic lineage- Implications in bone disorders -- Autophagy in Cancer Metastasis.
    Abstract: This book covers a wide range of topics that illustrate the various functions of autophagy in stem cells and offers insights on the mechanisms by which autophagy can regulate stem-cell self-renewal and facilitate specific differentiation programs. Stem cells are unique cells present in most multicellular animals and are essential for their survival. They have two unique properties: the ability to self-renew and the ability to differentiate into one or more cell types. These characteristics of stem cells have found immense therapeutic potential in regenerative medicine. Autophagy is a crucial membrane trafficking pathway that is essential for maintaining cellular homeostasis that involves sequestration of non-functional proteins, protein aggregates and damaged organelles in double-membraned vesicles called autophagosomes, which are subsequently targeted to the lysosome for degradation. The primary aim of this book is to provide knowledge of recent developments in our understanding of the role of autophagy in stem cells, including germline stem cells. Autophagy is considered a promising target for many diseases. Significant efforts are being developed to identify specific modulators of autophagy, which will aid in designing combinatorial therapeutic strategies that will allow significant improvements in regenerative medicine.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 41 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031173622
    Series Statement: Stem Cell Biology and Regenerative Medicine, 73
    URL: https://doi.org/10.1007/978-3-031-17362-2
    DOI: 10.1007/978-3-031-17362-2
    DDC: 571.978
    Language: English
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  • 25
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    Online Resource
    Tropical Forest Ecosystem Services in Improving Livelihoods For Local Communities (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotic communities. ; Forestry. ; Ecology . ; Ecosystems. ; Forestry. ; Ecology.
    Description / Table of Contents: Chapter 1. Conservation of Tropical Forest for the Well-being of Community -- Chapter 2. Forest Pathology in Ecosystem Services -- Chapter 3. Non-Timber Forest Problems: NTFPs in Conservation and Development Initiatives -- Chapter 4. Characterizing and assessing forest density and productivity of Ulu Muda Forest Reserve based on satellite imageries -- Chapter 5. Temporal Reduction of Forest Ecosystem Services and Drivers of Deforestation -- Chapter 6. A Trade-Off Analysis of Sustainable Landscape Planning: A Case Study of Sintang Regency (Heart of Borneo), Kalimantan -- Chapter 7. Land Use and Land Cover Change Prediction using ANN-CA model -- Chapter 8. Linking Blue-Green Infrastructure to Micoclimate and Human Thermal Comfort for Urban Cooling: A review -- Chapter 9. Assessing the Community Participation in Ecotourism at Ulu Muda Forest Reserve Malaysia -- Chapter 10. Improving Livelihood of Sugar Palm Community in Malaysia -- Chapter 11. Local community involvement in Mangrove Forest conservation and edutourism in Kampung Sijangkang -- Chapter 12. The Resilience of the Natural Resource Dependency of Indigenous People in a Wilderness Area: The Case of Virachey National Park, Cambodia -- Chapter 13. Reconciling the values and needs of wildlife and local communities: A way forward to deal with human-wildlife conflicts in Malaysia.
    Abstract: This edited book covers major importance of tropical forest diversity and its values to vegetation, wildlife, and the local community. It addresses the current issues and opportunities in the Southeast Asia’s tropical forests. This book lays the groundwork for a better understanding of tropical forest ecosystem services. Ecosystem services has four concepts: provisioning, regulating, cultural and supporting services. In an era of rapid population growth and increasing pressure on tropical natural resources, ecosystem services have become central to the discussion of climate change mitigation. The values of tropical forest ecosystem services deserve to be the highlighted when it comes to shaping responsible behaviors towards sustainable development goals (SDGs). This book is of interest and useful to researchers and academics teaching in the field of tropical forest conservation, tropical ecosystems, tropical products technology, ecotourism, forest plantation management, bio industrial economy, agroforestry business and marketing. Professionals, foresters, industrial entrepreneurs, ecologists, and a valuable source of reference to the relevant researchers and students in the region.
    Type of Medium: Online Resource
    Pages: VIII, 249 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811933424
    URL: https://doi.org/10.1007/978-981-19-3342-4
    DOI: 10.1007/978-981-19-3342-4
    DDC: 577
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  • 26
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    Online Resource
    Methods in Cancer Stem Cell Biology (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Biology Technique. ; Stem cells. ; Cancer Biology. ; Biological Techniques. ; Cancer Stem Cells. ; Stem Cell Biology.
    Description / Table of Contents: 1. On the origin of cancer -- 2. Culture of Cells: Basic Principles -- 3. Stem cell culture from embryos -- 4. Reprogramming of normal cells -- 5. Maintenance of human Pluripotent Stem Cells -- 6. Identification of cancer stem cells by different molecular markers -- 7. Enrichment of Cancer Stem Cell from malignant tumor -- 8. Isolation of single clonal cell from primary cultured cells and establishment of a cancer stem cell line -- 9. Artificial Generation of Cancer Stem Cells from Normal Stem Cells -- 10. Quick method to assess non-mutagenic carcinogens with iPS cells -- 11. Self-renewal potential of caner stem cells -- 12. Differentiation potential of cancer stem cells in vitro -- 13. Tumor Angiogenesis by cancer stem cells in vivo -- 14. Invasion and Metastatic potential of cancer stem cells in vitro -- 15. Metastatic potential of cancer stem cells In Vivo- 16. Anchorage-independent cell growth assay for Cancer Stem Cells: Tumorigenic assay in vitro -- 17. Tumorigenic potential of cancer stem cells in vivo -- 18. Development of immunoliposomes using monoclonal antibodies targeting cancer stem cells -- 19. In-vitro evaluation of anti-cancer stem cell drugs -- 20. In vitro Tumoroid Model Using Cancer Stem Cells.
    Abstract: This book describes the use of stem cells and cancer stem cell generation in the inflammatory microenvironment (cancer-inducing niche) using induced pluripotent stem cells. It provides step-by-step techniques and manuals for studying stem cell and cancer stem cell generation with different applications in cancer research. The development of induced pluripotent stem cells has provided a new approach to studying cancer initiation by producing cancer stem cells without introducing mutations or foreign genes. The book features the research of the authors’ group, which was the first to generate cancer stem cells from stem cells in the presence of inflammatory conditions. The 20 chapters if this book cover topics such as generating pluripotent stem cells, converting normal stem cells to cancer stem cells, enriching, isolating and evaluating cancer stem cells. Methods for evaluating the characteristics of cancer stem cells and possible therapies against them are also discussed. The book provides easy-to-follow protocols that help researchers in the study of cancer stem cells. Illustrations help readers understand how the method of cancer stem cell generation can be applied as an essential method for assessing the carcinogenic potential of various non-mutagenic compounds. It will be a useful resource for graduate students, researchers, technicians, and physicians working in academic, hospital, and pharmaceutical settings. .
    Type of Medium: Online Resource
    Pages: XVII, 243 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819913312
    URL: https://doi.org/10.1007/978-981-99-1331-2
    DOI: 10.1007/978-981-99-1331-2
    DDC: 571.978
    Language: English
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  • 27
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    Online Resource
    Hypoxia in Cancer: Significance and Impact on Cancer Therapy (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Cancer Treatment. ; Tumors Immunological aspects. ; Cancers. ; Cancer Therapy. ; Cancer Biology. ; Tumour Immunology.
    Description / Table of Contents: Chapter 1. Hypoxia and its Biological Implications for Cancer Therapy -- Chapter 2. Hypoxia's function in cancer -- Chapter 3. Role of Hypoxia and Reactive Oxygen Species in cancer biology -- Chapter 4. Hypoxic tumor microenvironment: driver for cancer progression -- Chapter 5. Hypoxia and Senescence: Role of Oxygen in Modulation of Tumor Suppression -- Chapter 6. Hypoxia Regulated Gene Expression and Metastasis -- Chapter 7. piRNA based cancer therapy in hypoxic tumor -- Chapter 8. MicroRNA Signatures of Tumor Hypoxia -- Chapter 9. Hypoxia and the Metastatic Cascade -- Chapter 10. Hypoxia and Extra Cellular Matrix-major drivers of tumor Metastasis -- Chapter 11. Role of Hypoxia in Cancer Therapy – Introduction -- Chapter 12. Hypoxic regulation of telomerase gene expression in cancer -- Chapter 13. CRISPR/Cas9-editing-based modeling of tumor hypoxia -- Chapter 14. Tumor-on-a-chip: Microfluidic models for Hypoxic tumor microenvironment -- Chapter 15. Imaging the Hypoxic Tumor microenvironment in cancer models -- Chapter 16. Hypoxia-targeting drugs as new cancer chemotherapy agents Hypoxia-targeting drugs as new cancer chemotherapy agents - Molecular Insights -- Chapter 17. Identification of Hypoxia targeting drugs in the tumor microenvironment and prodrug Strategies for Targeting Tumor Hypoxia -- Chapter 18. Hypoxia Induced Apoptosis in Cancer Development -- Chapter 19. Hypoxia in drug resistance and radioresistance.
    Abstract: This book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and treatment of cancer. The book provides an overview of hypoxia imaging, its biological relevance, and mechanism of action. It helps in understanding the molecular mechanisms of the regulation of senescence by hypoxia. It explores the contribution of hypoxia to immune resistance and immune suppression/tolerance and determines the hypoxia-responsive long non-coding RNAs in regulating hypoxic gene expression at chromatin, transcriptional, and post-transcriptional levels. Further, it presents the functional link between hypoxia and miRNA expressions and hypoxia-regulated miRNAs in cancer cell survival in a low oxygen environment. Lastly, it discusses the applications of tumor-on-a-chip technology for the understanding of hypoxia-tumor microenvironment. This book is a valuable source for oncologists and scientists working to understand the role of hypoxia in cancer and therapeutic approaches.
    Type of Medium: Online Resource
    Pages: XV, 447 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903139
    URL: https://doi.org/10.1007/978-981-99-0313-9
    DOI: 10.1007/978-981-99-0313-9
    DDC: 571.978
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  • 28
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    Online Resource
    Evolutionary Dynamics of Malignancy : The Genetic and Environmental Causes of Cancer (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cancer Animal models. ; Cancer Treatment. ; Cancer Genetic aspects. ; Cancer Biology. ; Cancer Models. ; Cancer Therapy. ; Cancer Genetics and Genomics. ; Cancer Microenvironment.
    Description / Table of Contents: Chapter 1: Cancer as a Disease of Cell Proliferation -- Chapter 2: Genetic and Chromosomal Instability -- Chapter 3: Cancer as a Disease of Defective Cell Cycle Checkpoint Function -- Chapter 4: The DNA Damage Checkpoint -- Chapter 5: Dynamics of the Spindle Assembly Checkpoint -- Chapter 6: Cancer as a Disease of Complexity: The Dynamics of Drug Resistance -- Chapter 7: Chronic Myeloid Leukaemia: a One-Hit Malignancy -- Chapter 8: Chronic Myelomonocytic Leukaemia: a Three-Hit Malignancy -- Chapter 9: The Cancer Stem Cell and Tumour Progression -- Chapter 10: Evading the antitumour immune response -- Chapter 11: Implications of Evolutionary Dynamics for Cancer Treatment and Prevention -- Chapter 12: In science, all conclusions are provisional.
    Abstract: Advances in cancer genomics are transforming our understanding of cancer, and have profound implications for its prevention, diagnosis, and treatment. Evolutionary dynamics suggests that as few as two mutations can cause transformation of normal cells into cancer stem cells. A process of Darwinian selection, involving a further three or more mutations, taking place over a period of years, can then result in progression to a life-threatening tumour. In many cases the immune response can recognise and eliminate the mutant cells, but most advanced tumours have mutations that activate immune checkpoints and enable the tumour to hide from the immune system. For the most hard-to-treat tumours, future progress will require molecular diagnostics to detect cancer-causing mutations in healthy subjects, and new drugs or vaccines that prevent the progression process. Chapters of this book deal with the signalling pathways that control cell division, and changes in these pathways in cancer cells. Three cell cycle checkpoints that are often mutated in cancer are analysed in detail. A discussion of chronic myeloid leukaemia illustrates the role of reactive oxygen species in driving progression from a chronic to an acute condition. A single drug that suppresses reactive oxygen can prevent disease progression and turn an otherwise deadly disease into a condition that can be managed to enable many years of normal life. Another chapter discusses chronic myelomonocytic leukaemia, a disease that involves both genetic and epigenetic change. Tumour progression is discussed as a multi-stage process in which cancer stem cells evolve into genetically unstable, invasive, metastatic, drug-resistant growths. Each of these stages can act as targets for drugs or immunomodulators, but the future of cancer treatment lies in understanding tumour dynamics, and arresting malignancy at the earliest possible stage. Evolutionary dynamics is a primarily mathematical technique, but the target readership will be tumour biologists, clinicians, and drug developers. Computational detail is provided in an online supplement, but the main text emphasises the implications of the dynamics for an understanding of tumour biology and does not require mathematical expertise.
    Type of Medium: Online Resource
    Pages: XIV, 269 p. 96 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031325731
    URL: https://doi.org/10.1007/978-3-031-32573-1
    DOI: 10.1007/978-3-031-32573-1
    DDC: 571.978
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  • 29
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    Biodiversity, Functional Ecosystems and Sustainable Food Production (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Food science. ; Biodiversity. ; Environmental sciences Social aspects. ; Ecosystems. ; Food Science. ; Biodiversity. ; Environmental Social Sciences.
    Description / Table of Contents: 1. Agro-biodiversity across the food chain -- 2. Emerging risks to plant health -- 3. Future-proofing Plants against Climate Change- A path to ensure Sustainable Food Systems -- 4. The role of Integrated Pest Management for sustainable food production: The soybean example -- 5. (Alternative approaches to pesticide use): Plant-derived pesticides -- 6. Antimicrobial use in animal food production -- 7. Impacts of environment-friendly unit operations on the functional properties of bee pollen -- 8. Microbiome applications for sustainable food systems -- 9. Healthier and sustainable food systems: integrating underutilized crops in a ‘Theory of Change Approach -- 10. Alternative proteins for food and feed.
    Abstract: In recent decades, practices like the cultivation of a few high-yielding crop varieties on a large scale, the application of heavy machinery and continued mechanization of agriculture, the removal of natural habitats, and the application of pesticides and synthetics have resulted in the simplification of agro-ecosystems. This has enabled a substantial increase in food production but has at the same time transformed landscapes. Indeed, there is a concern that a decline in biodiversity has affected microbiome activities that support processes across soils, plants, animals, the marine environment, and humans. Although they have increased food production, the above practices cannot be considered sustainable in long-term applications. Biodiversity, Functional Ecosystems, and Sustainable Food Production explore ecosystems in terms of crop and animal production, pest and disease control, nutrient cycling, and soil fertility. Chapters range from agro-biodiversity to antimicrobial use in animal food production to microbiome applications for sustainable food systems and the impacts of environment-friendly unit operations on the functional properties of bee pollen. By examining such topics about each other, the text emphasizes how food production, ecosystem function, food quality, and consumer health are all interconnected.
    Type of Medium: Online Resource
    Pages: X, 354 p. 90 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031074349
    URL: https://doi.org/10.1007/978-3-031-07434-9
    DOI: 10.1007/978-3-031-07434-9
    DDC: 577
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  • 30
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    Online Resource
    Faunal Ecology and Conservation of the Great Nicobar Biosphere Reserve (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Biotic communities. ; Biodiversity. ; Freshwater ecology. ; Marine ecology. ; Ecology. ; Ecosystems. ; Biodiversity. ; Freshwater and Marine Ecology.
    Description / Table of Contents: 1. Great Nicobar Biospehere reserve: An Overview -- 2. Floral diversity of great nicobar biospehere reserve Andaman & Nicobar Islands, INDIA -- 3. Odonata of great nicobar biosphere reserve -- 4. Butterfly diversity of great nicobar biospehere reserve -- 5. Aquatic beetles of great nicobar biosphere reserve - (Coleoptera: Noteridae, Dytiscidae, and Hydrophildae) -- 6. Moths (Lepidoptera) of great nicobar biosphere reserve -- 7. Termite fauna of great nicobar biosphere reserve, India -- 8. Scorpionida and amblypygi diversity of great nicobar biosphere reseve -- 9. Diversity and species abundance of spiders of great nicobar biosphere reserve -- 10. Non-Marine Molluscs of great nicobar biosphere reserve, andaman and nicobar island, India -- 11. Reptiles of great nicobar biosphere reserve -- 12. Fresh water and estuarine fishes of great nicobar islands -- 13. Diversity and species abundance of bird commnuities in great nicobar biosphere reserve, India -- 14. Present status and distribution of nicobar megapode megapodius nicobariensis in nicobar islands -- 15. Mammalian fauna of great nicobar biosphere reserve -- 16. Status and distribution of long-tailed macaque fascicularis umbrosa miler, 1902 in great nicobar biosphere reserve, India -- 17. Conservation perspectives of dugongs and sea turtles in andaman and nicobar islands -- 18. Mesozooplankton diversity in the marine waters of great nicobar island, andaman and Nicobar Archipelago -- 19. Current status of diversity of marine microplankton from great nicobar island, andaman and nicobar archipelago -- 20. Marine sponges of great nicobar biosphere reserve -- 21. Great Nicobar Biosphere reserve - A Biological treasure trove for scleractinan corals -- 22.Hydrozoan diversity and distribution in great nicobar biosphere reserve -- 23. Diversity and distribution of octocorals (Octocorollia) in great nicobar biosphere reserve -- 24. Status and distribution of sea anemone in great nicobar biosphere reserve -- 25. Polyclads of great nicobar biosphere reserve -- 26. Decapods (Crustacea: Decapoda) of great status of great Nicobar biosphere reserve -- 27. Current status of the marine polychaete (Annelida: Polychaeta) from Nicobar islands -- 28. Diversity and distribution of intertdial mollusca of great nicobar biosphere reserve. 29. Status and distribution of Opisthobranchs of Great nicobar isalnd, India -- 30. Diversity and distribution of echinoderms of great niocobar biosphere reserve, Andaman and Nicobar islands -- 31. Marine Icthyofaunal Diversity in great Nicobar Biosphere resere,- India. 32. Marine Mammals of the Nicobar group of Islands, India.
    Abstract: This edited book brings out a comprehensive account of the faunal diversity in Great Nicobar Biosphere Reserve which is part of the Sundaland Biodiversity hotspot. The main focus of this volume is to address the ecological and economic significance of the biodiversity of this region. The book provides latest information on the faunal diversity of Great Nicobar Biosphere. It focuses on various faunal communities of this regions such as Floral diversity, Butterflies, Moths, Dragonflies & Damselflies, Termites, Hymenoptera, Coleoptera, Scorpion, Spiders, Turtle, Nicobar megapode. Chapters in this volume also covers Reptiles & Amphibians, Fishes, Mammals, Land and freshwater Mollusca. Marine animals such as Opisthobranchs, Sponges, Scleractinian Corals and Soft corals, Sea Anemones, Polyclads, Marine Molluscs, Echinoderms are also discussed. It is of interest for the researchers, teachers, scientists, capacity builders, policy makers. Also serve as reading materials for graduate and post graduate students e.g., Wildlife Biology, Forestry, Environmental Science, Wildlife Ecology, Zoology, Life sciences, Parks/Sanctuaries managers, National and International scientists, policy makers will also find this to be a useful document.
    Type of Medium: Online Resource
    Pages: XVI, 666 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811951589
    URL: https://doi.org/10.1007/978-981-19-5158-9
    DOI: 10.1007/978-981-19-5158-9
    DDC: 577
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  • 31
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    Online Resource
    Neotropical Gradients and Their Analysis (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Evolution (Biology). ; Ecology Methodology. ; Biodiversity. ; Biotic communities. ; Population biology. ; Ecology. ; Evolutionary Ecology. ; Ecological Modelling. ; Biodiversity. ; Community and Population Ecology.
    Description / Table of Contents: 1. Introduction. Randall W. Myster -- 2. Mountain gradients in the Neotropics, a bracken fern perspective. Jorge Luis Avila Nuñez, Maria Pia Calcagno-Pissarelli, Miguel E. Alonso-Amelot -- 3. Effects of agricultural expansion on lotic benthic macroinvertebrate communities: a review and case study from Brazil. Elaine C. Corrêa and Ryan M. Utz -- 4. Plant competition across topographic gradients in Neotropical Cerrado savannas: an isotopic approach. Davi R. Rossatto and Augusto C. Franco -- 5. Diversity of aquatic macroinvertebrates along altitudinal gradients in Colombian. Cesar E. Tamaris-Turizo, Gabriel A. Pinilla-A and Juan D. González-Trujillo -- 6. Intraspecific trait variability of emblematic grass and tree species from Venezuelan savannas across extended physical gradients. Zdravko Baruch -- 7. Latitudinal trends in scorpion assemblages of Brazilian Atlantic Forest: do the Rapoport’s and Bergmann’s rules apply? André F.A. Lira, Alessandra R.S. Andrade and Stênio I.A. Foerster -- 8. Species diversity of three faunal communities along a successional cloud forest gradient. Juan Manuel Díaz-García, Fabiola López-Barrera, Eduardo Pineda, Jorge Valenzuela-González and Adriana Sandoval-Comte -- -- 9. Ecohydrological gradient in Neotropical montane ecosystems: From tropical montane forests to glacier. Conrado Tobón, Erick Castro, and Jorge Luís Ceballos -- 10. Communities of small terrestrial arthropods change rapidly along a Costa Rican elevation gradient. M. Alex Smith, Connor Warne, Kate Pare, Sarah Dolson, Elyssa Loewen, Kelsey Jones, Megan McPhee, Lauren Stitt, Lauren Janke, Rebecca M. Smith, Heather Coatsworth, Alexandre M. M. C. Loureiro, Angel Solis, Carlos F. Viquez, Josephine Rodriguez, Jose Fernandez-Triana, Michael J. Sharkey, James Whitfield, Alejandro Masís, María Marta Chavarría, Roger Blanco, Felipe Chavarria, Eugenie Phillips-Rodríguez, Roberto Fernández, Dunia Garcia, Guillermo Pereira, Harry Ramirez, Manuel Pereira, Winnie Hallwachs and Daniel H. Janzen -- 11 Neotropical gradients of insect groups in Brazilian mountains. Lucas Neves Perillo, Frederico de Siqueira Neves, Flávio Siqueira de Castro and Ricardo Ribeiro de Castro Solar -- 12. Altitudinal Pattern of Soil Organic Carbon and Nutrients in a Tropical Forest in Puerto Rico. Dingfang Chen, Mei Yu, Grizelle González, Qiong Gao -- 13. Elevational and latitudinal species richness patterns of dung beetles in North and South America and the role played by historical factors. Jorge M. Lobo and José Gutiérrez -- 14. Diversity patterns of vascular plant groups along gradients of elevation and disturbance in Mexico. Jorge A. Gómez-Díaz, Alma P. Bautista-Bello, César I. Carvajal-Hernández, Valeria Guzmán-Jacob, María Leticia Monge-González and Thorsten Krömer -- 15 Gradients and the Structure of Neotropical Metacommunities: Effects of Disturbance -- Elevation, Landscape Structure, and Biogeography. Steven J. Presley, Michael R. Willig -- 16. Socioecological gradients: contesting traditional ecoclines to explain the high biocultural diversity of the Andean verdant. Fausto Sarmiento, Andreas Haller, Domenico Branca, Christiam Aguirre, Vladimir Kremsa, Carla Marchant, Masahito Yoshida -- 17. Conclusions, synthesis and future directions. Randall W. Myster.
    Abstract: The importance of the Neotropics to the world's climate, biogeochemical cycling and biodiversity cannot be questioned. This book suggests that gradients are key to understanding both these issues and Neotropical ecosystem structure, function and dynamics in general. Those gradients are either spatial, temporal or spatio-temporal, where many temporal and spatio-temporal gradients are initiated by disturbances (e.g., tree-fall, landslide, cultivation). And in particular for the Neotropics, three large spatial gradients - latitude, longitude, altitude (elevation) - are of critical importance. The editor has over 30 years of experience investigating Neotropical gradients in Costa Rica, Puerto Rico, Peru and Ecuador, and has published 5 previous books on different aspects of the Neotropics. Once again he has assembled top-shelf Neotropical scientists and researchers, here to focus on gradients: their nature, interactions and how they structure ecosystems.
    Type of Medium: Online Resource
    Pages: XVII, 468 p. 114 illus., 84 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031228483
    URL: https://doi.org/10.1007/978-3-031-22848-3
    DOI: 10.1007/978-3-031-22848-3
    DDC: 577
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    Genetics and Epigenetics of Breast Cancer (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Cancer Genetic aspects. ; Cancer Treatment. ; Cancer Biology. ; Cancer Genetics and Genomics. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1. Breast cancer -- Chapter 1.1. Epidemiology -- Chapter 1.2. Etiology -- Chapter 1.3. Types of breast cancer -- Chapter 1.4. Signs and symptoms -- Chapter 1.5. Stages -- Chapter 1.6. Diagnosis -- Chapter 1.7. Treatment -- Chapter 2. Genetic landscape of breast carcinogenesis -- Chapter 2.1. Hormone receptor positive breast cancer -- Chapter 2.1. Her2 positive breast cancer -- Chapter 2.2. Triple negative breast cancer -- Chapter 3. Epigenetic involvement in breast carcinogenesis -- Chapter 3.1. Histone modification -- Chapter 3.2. DNA methylation -- Chapter 3.3. miRNA -- Chapter 4. Breast cancer control -- Chapter 4.1. Conventional drugs targeting Genetic and Epigenetics in Breast cancer -- Chapter 4.2. Pitfalls of conventional therapy -- Chapter 4.3. Natural remediation -- Chapter 5. Conclusion.
    Abstract: This book discusses the contribution of genetics and epigenetics alterations in the initiation, development, and recurrence of breast cancer. It also reviews the potential of translating the epigenetic alterations into diagnosis, prognosis, and breast cancer therapy. The initial chapters explore the epigenetics, etiology, and conventional treatment strategies for breast cancer. The subsequent chapters discuss the genetic landscape and cover three main epigenetic modulation mechanisms; histone modification, DNA methylation, and miRNA silencing. Further, the book explores the potential of epigenetic drugs in treating breast cancer. Lastly, it covers the phytochemicals targeting epigenetic modulators in breast cancer treatment. This book is an essential source for researchers and practitioners interested in exploring the potential of epigenetics modulators in breast cancer treatment.
    Type of Medium: Online Resource
    Pages: X, 87 p. 13 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811999253
    URL: https://doi.org/10.1007/978-981-19-9925-3
    DOI: 10.1007/978-981-19-9925-3
    DDC: 571.978
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    Cancer Stem Cells: Basic Concept and Therapeutic Implications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Stem cells. ; Cancer Treatment. ; Cancer Genetic aspects. ; Cancer Stem Cells. ; Cancer Therapy. ; Cancer Biology. ; Cancer Genetics and Genomics.
    Description / Table of Contents: 1. Introduction and perspective in carcinogenesis -- 2. Origin and Development of Cancer Stem Cells -- 3. Detection and Isolation of Cancer Stem Cells -- 4. The genetic and epigenetic landscape of cancer stem cells -- 5. Metabolism of Cancer Stem Cell -- 6. Plasticity of Cancer Stem Cell -- 7. Cancer Stem Cells in Cancer Initiation and Progression -- 8. Cancer Stem Cells and Metastasis -- 9. Roles of Cancer Stem Cells in Therapy resistance and Disease Recurrence -- 10. Novel therapeutics targeting cancer stem cell surface markers -- 11. Therapeutics targeting cancer stem cells signalling pathways -- 12. Cancer stem cells therapeutics delivery and EPR effect -- 13. Immunotherapy against cancer stem cells -- 14. Engineering nanobody targeting cancer stem cells -- 15. Biological barriers for drug delivery to cancer stem cells -- 16. Cancer Stem Cell Markers in Haematological Malignancies -- 17. Diagnostic and Prognostic Significance of Cancer Stem Cells Surface Markers -- 18. Diagnostic and prognostic implications of cancer stem cells transcription factors -- 19. Diagnostic and prognostic significance of intracellular markers of CSCs in patients with cancers. .
    Abstract: This book comprehensively reviews the role of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to anticancer therapies. The initial chapters examine the methods and procedure of the detection, isolation, and characterization of CSCs. It also introduces various epigenetic pathways that contribute to cancer initiation and tumorigenesis, particularly regarding the maintenance and survival of CSCs. It also explores the role of CSCs metabolism and the mechanisms of metabolic plasticity of CSCs in cancer biology. Further, it also presents the implications of CSCs on the origin of tumor heterogeneity and on heterogeneity of the therapeutic response. Towards the end, this book highlights the different immunotherapeutic approaches targeting CSCs with the potential of strongly improving cancer outcomes. This book offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications.
    Type of Medium: Online Resource
    Pages: XVI, 372 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819931859
    URL: https://doi.org/10.1007/978-981-99-3185-9
    DOI: 10.1007/978-981-99-3185-9
    DDC: 571.978
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    Restoration of Ecosystems – Bridging Nature and Humans : A Transdisciplinary Approach (2023)
    Berlin, Heidelberg :Springer Berlin Heidelberg :
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    Keywords: Biotic communities. ; Human geography. ; Ecosystems. ; Human Geography.
    Description / Table of Contents: Introduction to Restoration Ecology - Which habitat should be restored? Reference ecosystems for restoration -- Measures for ecosystem restoration -- Reintroduction of plant and animal species -- For dealing with non-native species in ecosystem restoration -- Monitoring and success control -- Forests -- Moors -- Subalpine and alpine grasslands -- Running waters -- Natural and anthropogenic still waters - Ecosystems and types of use influenced by salt - Marine habitats in the North Sea and Baltic Sea - Heath in the lowlands and mountains - Meadows and pastures in mesophilic, moist and calcareous locations - Lean or dry sand grasslands of the coasts and des Inland areas - Fields - Traditional agroforestry systems - Urban ecosystems - Mining or open pit sites and landfills.
    Abstract: Bridging the natural and social sciences, this cross-disciplinary textbook comprehensively presents both the scientific basis of restoration ecology and practical aspects of ecosystem restoration. In doing so, it highlights the diversity of land-use types with a focus on Central Europe and presents case studies of practical restoration projects. The textbook provides a profound and up-to-date, but also critical overview of the state of knowledge for students dealing with the environment, scientists as well as practitioners. This book opens up the broad spectrum of degraded ecosystems of Central European natural and cultural landscapes. In further chapters, marine ecosystems and their restoration as well as development potentials but also limitations of ecosystem restoration are discussed in more detail. The ecological basics are extended by an interdisciplinary perspective taking into account environmental ethics, sociology, anthropology and economics. In addition to providing an up-to-date overview of the various fields and areas of activity in restoration ecology and ecosystem restoration, this textbook offers a valuable foundation for science, study and practice. Readers will also receive guidance on literature searches and critical fact analysis, and instructors on teaching in Higher Education and interdisciplinary approaches to discussions in restoration ecology. The author Stefan Zerbe is a landscape ecologist and teacher and researcher at the Free University of Bozen-Bolzano in South Tyrol (Italy). He is particularly interested in restoration ecology and building interdisciplinary bridges between the natural and social sciences. Against this background, he was in charge of developing and managing two international master’s programs. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent intense human revision was done primarily in terms of scientific terms, style and content so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.
    Type of Medium: Online Resource
    Pages: XXI, 723 p. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783662656587
    URL: https://doi.org/10.1007/978-3-662-65658-7
    DOI: 10.1007/978-3-662-65658-7
    DDC: 577
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    Ecology of Himalayan Treeline Ecotone (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Ecology . ; Forestry. ; Ecology. ; Forestry. ; Terrestial Ecology.
    Description / Table of Contents: 1 Treeline Research in Himalaya: Current Understanding and Future Imperatives -- 2 Capturing Himalayan Timberline Dimensionand Ecological Attributes In Warming Climate Through Team Science -- 3 Temperature lapse rate in different himalayan treeline environments: regional analysis of patterns, seasonality and variability -- 4 Relationship between timberline elevation and climate in sikkim himalaya -- 5 The treeline ecotone in Rolwaling Himal, Nepal: Pattern-process relationshipsand treeline shift potential -- 6 Challenges of timberline mapping in the himalaya: a case study of sikkim himalaya -- 7 Mapping the Spatial Patterns of Biodiversity Along the Alpine Treeline Ecotone in EasternHimalaya Using Information Theory -- 8 Quantifying Variation In Canopy Height From Lidar Data As A Function Of Altitude Along Alpine Treeline Ecotone In Indian Himalaya -- 9 Patterns of Plant Taxonomic, Life-form and Phylogenetic Diversity at a Treeline Ecotone in Northwestern Himalaya: Role of Aspect and Elevation -- 10 Vegetation Structure along an Elevation Gradient at the Treeline Ecotone of Eastern Himalayan forests in Sikkim -- 11 Patterns of Plant Species Richness across the Himalayan Treeline Ecotone -- 12 Lichen Diversity in High Elevations of Western Himalaya with special reference to Treeline Ecotone: Conservation and Indicator Value -- 13 Community-Level Lichen Diversity Assessment In Alpine Zone Of Indian Himalaya: Climate Change Implications -- 14 Lower Plants of Tungnath-Chopta Timberline Zone, Garhwal Himalaya -- 15 Phenological response of treeline ecotone tree species to global warming in Western Himalaya -- 16 Water Relations Of The Indian Himalayan Treeline Species -- 17 Herbaceous Vegetation Structure And Phenology At Treeline Ecotone In Relation To Natural Snowmelt -- 18 Responses Of Herbaceous Species Of Alpine Treeline To Elevated Co2 -- 19 Age-Girth Stand Structure of Himalayan fir and Growth-NDVI relationship in the Treeline transects of western Himalaya: An ecological perspective -- 20 Response Of Radial Growth In Abies Pindrow (Royle Ex D.Don) Royle To Climate At Treeline Ecotone In The Northwestern Himalaya -- 21 Pastoralism in Timberline Forests of Western Himalaya -- 22 Treeline Research In The Nepal Himalaya: Status And Future Prospects. .
    Abstract: This book brings together comprehensive multi-disciplinary knowledge on diverse aspects of the Himalayan treeline ecotone which is considered one of the most sensitive ecosystems to climate change. The contents of this book are based on the results of extensive research and provide a holistic understanding of the treeline ecotone in Himalaya. The book will serve as an important reference manual and a textbook on treeline ecology. The book is unique in the sense that it provides an engaging account of almost all the aspects of the treeline ecotone, such as taxonomic, functional and phylogenetic species diversity, temperature lapse rates, tree phenology, water relations, and stress physiology, tree ring width chronology, and climate relationships and the role of treeline ecotone in human sustenance in the Indian Himalayan region The treelines in the Himalaya, being the highest in the Northern Hemisphere (up to 4900 m), are among the least investigated systems and hence this book is timely and fills all-important knowledge gaps vis-à-vis treeline shifts, physiognomic, structural, and functional changes in mountain landscapes and ecosystems, particularly under the changing climate This book, for the first time, summarizes evidence-based knowledge about various aspects of treeline ecotone in Himalaya that was largely generated through a well-coordinated a team science approach. The book will be of interest to ecologists, climatologists, dendrochronologists, foresters, plant physiologists and resource managers and policy planners for a better understanding of the organization and dynamics of this fragile ecosystem in relation to climate change and other anthropogenic stresses that are rampant in the Himalaya. The book lays a solid foundation for further investigation of the ecology and dynamics of the treeline ecotone in the Himalayas and provides a rationale for pursuing a team science approach for macroecological investigations.
    Type of Medium: Online Resource
    Pages: XXVI, 569 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811944765
    URL: https://doi.org/10.1007/978-981-19-4476-5
    DOI: 10.1007/978-981-19-4476-5
    DDC: 577
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    Cytokine and Chemokine Networks in Cancer (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Tumors Immunological aspects. ; Therapeutics. ; Cancers. ; Tumour Immunology. ; Therapeutics.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Expression pattern of Chemokines in Cancer -- Chapter 3_Implications of Cytokine-Chemokine Heterogenity in Cancer -- Chapter 4_Cytokine and chemokines networks in cancer stemness -- Chapter 5_Cytokine and chemokines networks in angiogeneis -- Chapter 6_Role of Cytokine-Chemokine cascades in Epithelial to Mesenchymal Transition -- Chapter 7_Role of Chemokines in establishment of Metastatic Niche -- Chapter 8_CXCL12-CXCR4 axis in Metastasis -- Chapter 9_Chemokine and cytokine networks in the tumor microenvironment -- Chapter 10_CXCL9, CXCL10, CXCL11/CXCR3 axis and Immune Activation -- Chapter 11_CXCL8-CXCR1/2 axis in cancer and inflammatory diseases -- Chapter 12_Cytokine and Chemokine Networks in Therapeutic Resistance -- Chapter 13_Prognostic and diagnostic significance of Chemokines and cytokines in cancer -- Chapter 14_Therapeutic implications of Chemokines and cytokines networks in cancer -- Chapter 15_Chemokines in cancer therapy.
    Abstract: Cytokine and Chemokine Networks in Cancer" provides a comprehensive exploration of the roles of cytokines and chemokines in cancer biology. It offers valuable insights into their diagnostic, prognostic, and therapeutic implications, making it a valuable resource for researchers, clinicians, and students interested in the field of cancer immunology and therapy. This book illustrates the importance and significance of the cytokine and chemokine signaling networks in tumor development and progression. It describes the complex networks mediated by cytokine and chemokine receptors promoting tumor cell proliferation, site-directed metastasis, and activation of angiogenic switch in tumor cells. The books also shed light on the heterogeneity of cytokines and chemokine in solid malignancies and their impact on tumor progression and therapeutic outcomes. The chapters provide current information about the types of cytokine-chemokine interactions in promoting cancer stem cell-like characteristics, epithelial to mesenchymal transition, and modulation of the tumor microenvironment. The significance of the complex interactions in cancer biology in the light of therapeutic resistance is also highlighted. The chapters also describe recent advancements in the therapeutic potential of targeting the pro-tumor cytokine and chemokine networks and limiting tumor cell metastasis. Finally, the book also provides a comprehensive yet representative description of a large number of challenges associated with targeting these vital chemokine-cytokine networks. Given its content, the book provides valuable information for researchers in the field of cancer biology and molecular medicine.
    Type of Medium: Online Resource
    Pages: XVII, 440 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819946570
    URL: https://doi.org/10.1007/978-981-99-4657-0
    DOI: 10.1007/978-981-99-4657-0
    DDC: 571.978
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    The Macroecological Perspective : Theories, Models and Methods (2023)
    Cham :Springer International Publishing :
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    Keywords: Ecology . ; Biodiversity. ; Biotic communities. ; Population biology. ; Biogeography. ; Ecology. ; Biodiversity. ; Community and Population Ecology. ; Biogeosciences.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter Two. Theories and Models -- Chapter 3. The Structure of Macroecological Data -- Chapter 4. Structure and Dynamics of Geographic Ranges -- Chapter 5. The Macroecological Understanding of Ecological Niches -- Chapter 6. Richness and Diversity Patterns -- Chapter 7. Macroecological Assemblages -- Chapter 8. Patterns in Body Size -- Chapter 9. From Theoretical to Applied Macroecology -- Chapter 10. Concluding Remarks. .
    Abstract: This comprehensive volume discusses the patterns and processes analyzed in macroecology with a distinct look at the theoretical and methodological issues underlying the discipline as well as deeper epistemological matters. The book serves as a synthesis of macroecological literature that has been published since Brown and Maurer proposed and defined the term “macroecology” in 1989. Author José Alexandre Felizola Diniz-Filho draws from the different disciplines and branches (ecology, evolutionary biology, physiology, behavioral sciences, climatology, and paleontology) that make up macroecology to present a full, holistic picture of where the discipline stands. Through ten chapters, Diniz-Filho moves from a discussion of what macroecology actually is to macroecological modeling to the more applied side of the discipline, covering topics such as richness and diversity patterns and patterns in body size. The book concludes with a synthesis of how macroecological research is done in a theoretical and operational sense as well as unifying explanations for each of the macroecological patterns discussed, moving on to evaluate which theories and models are still useful and which ones can be abandoned. The book is intended for academics, young researchers and students interested in macroecology and conservation biogeography. In addition, because of the integrative nature of macroecology and the theoretical and methodological background in the book, it can be of interest to researchers working in related fields including but not limited to ecology and evolutionary biology.
    Type of Medium: Online Resource
    Pages: XX, 449 p. 101 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031446115
    URL: https://doi.org/10.1007/978-3-031-44611-5
    DOI: 10.1007/978-3-031-44611-5
    DDC: 577
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    Redox Regulation and Therapeutic Approaches in Cancer (2023)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Metabolism. ; Cancer Treatment. ; Biochemistry. ; Oxidation-reduction reaction. ; Cancer Metabolism. ; Cancer Therapy. ; Redox Biology.
    Description / Table of Contents: 1. ROS, redox regulation and signaling in cancer cells -- 2. ROS and redox regulation/signaling and metabolism in cancer stem cells -- 3. . ROS/Redox regulation with dietary phytochemicals and role in anticancer activity -- 4. ROS/Redox signaling and apoptosis/necroptosis/autophagy in cancer -- 5. Cancer Metastasis, ROS/redox signaling and PCD resistance/redox metabolism -- 6. Immune system, redox signaling and cancer immunity -- 7. P53, ROS- redox regulation signaling, metabolic reprogramming and autophagy in cancer -- 8. Cell cycle, DNA damage-repair systems and impact of redox regulation in cancer -- 9. ROS, redox regulation and anticancer therapy -- 10. Perspectives in ROS/redox regulation cancer therapy.
    Abstract: This book aims to provide an association of the major redox-sensitive pathways and networks involved in cancer. The initial chapter of the book discusses basic information about oxidative stress, its generation, and regulation (redox regulation or redox homeostasis) via cell signaling in normal and cancer cells. The book also explores antioxidants and metabolic events in cancer cells compared to normal cells. It further covers the application of nanoparticles in redox regulation in cancer cells. The role of redox regulation in cancer therapy, its influence, and its involvement in programmed cell death (PCD), metastasis, immune system, p53, and cell cycle/DNA damage repair pathways have been discussed in separate chapters. It further reviews the importance of dietary phytochemicals in redox regulation in normal and cancer pathophysiology. Towards the end, the book focuses on the role of redox balance, especially in ROS-dependent cellular processes in cancer stem cells.
    Type of Medium: Online Resource
    Pages: XI, 431 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819973422
    URL: https://doi.org/10.1007/978-981-99-7342-2
    DOI: 10.1007/978-981-99-7342-2
    DDC: 571.978
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    Terrestrial Environment and Ecosystems of Kuwait : Assessment and Restoration (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Ecology . ; Water. ; Hydrology. ; Sustainability. ; Environmental management. ; Agriculture. ; Terrestial Ecology. ; Water. ; Sustainability. ; Environmental Management. ; Agriculture.
    Description / Table of Contents: Part I. Soils, Geographical and Climatic Features, Eco-Resources, and Desertification -- Chapter 1. Potential Threats to Soil Functions and Mitigation Options for Sustainable Uses -- Chapter 2. Perspectives of Geography, Environment, and Physiography of Kuwait -- Chapter 3. Climate and Climate Change Aspects of Kuwait -- Chapter 4. Ecological Footprint and Biocapacity of Kuwait and Proposed Eco-Resources Management Strategies – A Review -- Chapter 5. Desertification – A Central Problem to Restore Ecosystems -- Part II. Water Resources, Salinization Aspects and Modeling -- Chapter 6. Current Status, Challenges and Future Management Strategies for Water Resources of Kuwait -- Chapter 7. Groundwater Salinization in Kuwait: A Major Threat to Indigenous Ecosystems -- Chapter 8. Predicting the Behavior of the Salt/Fresh-Brackish Water Transition Zone During Scavenger Well Pumping: 1. Numerical Model Development and Testing -- Chapter 9. Predicting the Behavior of the Salt/Fresh-Brackish Water Transition Zone During Scavenger Well Pumping: 2. Model Application in Kuwait and Pakistan -- Part III. Terrestrial Ecosystems and their Management -- Chapter 10. Terrestrial Habitats and Ecosystems of Kuwait -- Chapter 11. Native Vegetation and Flora of Kuwait -- Chapter 12. Wildlife of the Terrestrial Ecosystems of Kuwait -- Chapter 13. Major Threats to the Terrestrial Ecosystems and Proposed Conservation Practices -- Chapter 14. Kuwait Deserts and Ecosystems in the Context of Changing Climate -- Part IV. Agriculture, Food Security and Water Footprint of Crops -- Chapter 15. Prospective of Agricultural Farming in Kuwait and Energy-Food-Water-Climate Nexus -- Chapter 16. Agricultural Water Footprint of Major Crops in Kuwait Compared to the World Average – A Review.
    Abstract: This book is an outcome of collaborative efforts of a multidisciplinary team of scientists. The core objective of this book is to provide cross-sectoral information on the different aspects of the terrestrial environment and ecosystems of Kuwait. The book will be considered as a ready source of information for those seeking information on the terrestrial environment and ecosystems, assessment and restoration, as well as sustainable uses and management. In spite of Kuwait’s hyper-arid environment, it is rich in natural resources including a wide range of native plants, animal species, different habitats, protected areas, diversified soils and water and oil resources. While the desert of Kuwait constitutes various features, such as sand sheet, sand dunes, nebkhas, inland and coastal sabkhas, rock outcrop, wadis and farming areas, it is rich in flora and fauna (native plants, mammals, birds, reptiles, etc.). Due to changing climate, deserts of Kuwait as well as other countries are under severe threat of degradation and the degradation may be irreversible. To realize these impacts, an effort is being made to provide a ready source of information to highlight the potential threats to the terrestrial ecosystems and formulate adaptation and mitigation strategies for long-term ecosystems services in Kuwait as well as other countries located in a desert environment, such as Gulf Cooperation Council Countries, Africa and countries in the Arab region. The book includes sixteen chapters covering multidiscipline subjects (such as natural resources, climate and climate change, geographical features, terrestrial habitats, ecosystems and threats, water and soil resources, agriculture, food security, water-energy-food-climate nexus, green-grey-blue water footprints of various crops, etc.). Thus, this book is a unique resource that provides the latest scientific information in a single volume.
    Type of Medium: Online Resource
    Pages: XXV, 420 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031462627
    URL: https://doi.org/10.1007/978-3-031-46262-7
    DOI: 10.1007/978-3-031-46262-7
    DDC: 577
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    Microplastics in the Mediterranean Sea : Impacts on Marine Environment (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Biotic communities. ; Population biology. ; Ecology. ; Freshwater and Marine Ecology. ; Pollution. ; Community and Population Ecology. ; Ecosystems.
    Abstract: The book provides for the first time an overview of the latest scientific studies conducted on micro and nano plastic pollution in the Mediterranean Sea both from the biological and environmental point of view as well as from the chemical point of view in order to have a more real idea of the current situation.
    Type of Medium: Online Resource
    Pages: XII, 109 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031304811
    Series Statement: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-3-031-30481-1
    DOI: 10.1007/978-3-031-30481-1
    DDC: 577
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    Ecosystem Restoration: Towards Sustainability and Resilient Development (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Biodiversity. ; Ecology Methodology. ; Ecology. ; Biodiversity. ; Ecological Modelling.
    Description / Table of Contents: Chapter 1. Ecological restoration: An Overview of Science & Policy Regime -- Chapter 2. Lifestyle for Environment: Life Mission and Synergies with Eco-restoration -- Chapter 3. Optimal Management of Potential Water and Sediment Yield from Urban Hilly Watershed -- Chapter 4. Mainstreaming Peri-Urban Ecosystems for Urban Resilience through Policy-Planning Framework: An Opportunity Analysis for Indian Cities -- Chapter 5. Urban Forest and Ecosystem Services Intercede Urban Habitat in Delhi -- Chapter 6. Restoration and rejuvenation of rivers, streams and wetlands: Challenges and way forward -- Chapter 7. Ecosystem services for Water Management: A review of global approaches and experiences -- Chapter 8. Rejuvenation of Rivers in India-A Case Study on efforts for Rejuvenation of River Ganga -- Chapter 9. Rejuvenation of Kukrail Drain -- Chapter 10. Hydrological modelling using HEC-HMS and estimation of the flood peak by Gumbel’s method of Hasdeo Basin, Chhattisgarh, India -- Chapter 11. Comparing Runoff of NRCS-CN Method and Observed Runoff Data A Case Study -- Chapter 12. Artificial neural network models for rainfall-runoff modeling in India- studies from of Kolar and Kuttiyadi River watersheds -- Chapter 13. Analysis of urbanization and assessment of its impact on ground water & land use land cover using GIS techniques – Case study of Bhopal & Gurugram district -- Chapter 14. Application of Water Accounting Plus Framework for the assessment of the Water consumption pattern and Food security -- Chapter 15. Comparison of Probability Distributions for Extreme Value Analysis and Predicting Monthly Rainfall Pattern using Bayesian Regularized-ANN -- Chapter 16. An Indexing Method for Evaluating Managerial Effectiveness of a Watershed Project and Functional Involvement of Participant Organisations -- Chapter 17. Pathways to build resilience towards the impact of climate change on the Indian Sunderban -- Chapter 18. Eco-restoration for Climate Resilience and Disaster Risk Reduction -- Chapter 19. Ecosystems and Nature - Based Solutions (NbS) for Health Protection and Epidemic Resilience -- Chapter 20. Fresh Water Ecosystem Conservation for Social Protection, Business, and Local Economy.
    Abstract: This edited book offers coverage towards SDG 15 in particular, but it provides for all the SDGs in general. The book is an inclusive comprehension on ecosystem restoration and sustainability including agricultural and ecosystem resilience, the role of biodiversity, climate change and water resources, hydrological modelling, extreme events, disaster risk and management, sustainable policy making on disaster management. The world is facing diverse and severe challenges. Millions of people are suffering from the catastrophic effects of extreme disasters, climate emergencies, water and food insecurity, and the repercussions of COVID-19 pandemic. Ecosystems are essential players in people’s capacity to meet these challenges. Hence, managing them and protecting their resources in sustainable ways is crucial. The book ‘Ecosystem Restoration: Towards Sustainable and Resilient Development’ provides comprehensive information on fundamentals, approaches and latest developments in the field of ecosystem restoration, resilience and sustainability. This book is of interest to teachers, researchers, climate change scientists, and valuable source of reference to the professionals and students in the relevant disciplines. Besides, the book serves as additional reading for graduate students of water, ecology, restoration forestry, soil science, and environmental sciences. National and international ecological policy makers, scientists and planners will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XVIII, 366 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936878
    Series Statement: Disaster Resilience and Green Growth,
    URL: https://doi.org/10.1007/978-981-99-3687-8
    DOI: 10.1007/978-981-99-3687-8
    DDC: 577
    Language: English
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    Online Resource
    Circular Economy Adoption : Catalysing Decarbonisation Through Policy Instruments (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Environment. ; Human ecology Study and teaching. ; Environmental policy. ; Ecology. ; Environmental Sciences. ; Environmental Studies. ; Environmental Policy.
    Description / Table of Contents: Part 1. Decarbonisation and Policies for Circular Economy adoption -- Chapter 1. Circular Economy Catalysing Decarbonisation -- Part 2. Policy supports toward Circular Economy -- Chapter 2. Policies and Practice of Sound Material Cycle Society in Japan - transition towards the Circular Economy.-Chapter 3. The pathway towards circular economic development in China: Policies, case studies and the role of universities -- Chapter 4. Circular Economy Policies and Innovations in Africa -- Chapter 5. Waste Management in Indonesia: Strategies and Implementation of Sustainable Development Goals (SDGs) and Circular Economy -- Part 3. Implementation Status of Circular Economy Concepts -- Chapter 6. On the Way to Circular Economy: Türkiye’s Waste Management and Zero Waste Project -- Chapter 7. Circular economy transition in EU and Italy in key priority sectors: policies, initiatives and perspectives -- Chapter 8. Status of the adoption and practice of circular economy in Mexico -- Part 4. Circular Economy adoption in Industries -- Chapter 9. Circular Manufacturing Transformation: manufacturing perspectives, examples and experiences from implementation of Circular Economy in Asia -- Chapter 10. The circular economy, employment and low carbon in the UK manufacturing sector -- Chapter 11. Circular Economy through technology for Waste-to-Energy -- Chapter 12. Utilization of household sewage sludge - the effect of the temperature of pyrolysis on the chemical properties -- Chapter 13. Shifting toward Resource Management in Remote Area: A Case Study of Lake Toba, Indonesia -- Chapter 14. Circular Bioeconomy through Anaerobic Digestion.
    Abstract: This edited book brings out a comprehensive collection of information on principle and policy of circular economy. It deals with the general principles, pathways of circular economic development in different countries, use of circular economy in achieving sustainable development goals. The book covers policy instruments that helps implementing resource efficient processes, strategies of implementing circular economy concepts, Decarbonisation, and developing business promoting circular economy principles. The circular economy has gained increasing prominence as a tool which presents solutions to some of the world’s most pressing sustainable development challenges. By addressing root causes, the concept of a circular economy, an economy in which waste and pollution do not exist by design, products and materials are kept in use, and natural systems are regenerated provides promise to achieving SDGs. This book is of interest and use to practitioners, capacity builders and policymakers, entrepreneurs, NGOs, general people, and valuable source of reference to the relevant researchers and students in global markets. As circular economy is gaining momentum and interest in general, the book serves as reading material for undergraduate and graduate students in any field specifically environmental science, waste management, medical science as well as environmental management at national and international level.
    Type of Medium: Online Resource
    Pages: XIV, 468 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819948031
    URL: https://doi.org/10.1007/978-981-99-4803-1
    DOI: 10.1007/978-981-99-4803-1
    DDC: 577
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  • 43
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    Online Resource
    Biodiversity in India: Status, Issues and Challenges (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Conservation biology. ; Biotic communities. ; Population biology. ; Plant ecology. ; Animal culture. ; Ecology. ; Conservation Biology. ; Community and Population Ecology. ; Plant Ecology. ; Animal Science.
    Description / Table of Contents: Section 1 -- Chapter 1. Introduction -- Section 2. Plant Diversity -- Chapter 2. Status, issues and challenges of biodiversity:Lower plants (Non-vascular) -- Chapter 3. Status, issues and Challenges of Biodiversity:Higher Plants -- Chapter 4. Status, issues and challenges of biodiversity: Trees and Shrubs -- Chapter 5. Underutilized Plant Strength of India -- Section 3. Faunal Diversity -- Chapter 6. Status, Issues and Challenges of Biodiversity: Invertebrate -- Chapter 7. Diversity, Distribution and Endemicity of Herpetofauna in Different Biogeographic Zones and Biodiversity Hotpots of India -- Chapter 8. Status, Issues, and Challenges of Biodiversity: Wild Animals -- Chapter 9. Indian Avian Diversity:Status, Challenges and Solutions -- Chapter 10. Status, Issues and Challenges of Indian Livestock Biodiversity -- Section 4. Ecosystem Diversity -- Chapter 11. Agricultural Crop Diversity: Status, Challenges and Solutions -- Chapter 12. Biodiversity of Agriculturally Important Insects: Status, Issues and Challenges -- Chapter 13. Biodiversity Issues and Challenges:Non-Agriculture Insects -- Chapter 14. Status, issues and challenges of biodiversity: Forest Insects -- Chapter 15. Status, Issues and Challenges of Biodiversity: Marine Biota -- Chapter 16. Diatoms the living jewels their biodiversity, phycosphere and associated phenotypic plasticity: a lesson to learn from current pandemic of corona virus -- Chapter 17. Plant Diversity at Ecosystems level in India: Dynamics and Status -- Chapter 18. Faunal Diversity at Ecosystems level in India: Dynamics and Status -- Section 5. Challenges and reasons of Biodiversity loss -- Chapter 19. Challenges on Account of Invasive Alien Terrestrial Plants -- Chapter 20. Alien Invasive Aquatic Fauna:Challenges and Mitigation -- Chapter 21. Reasons of Biodiversity Loss in India -- Section 6. Efforts Conservation -- Chapter 22. Conservation of National Biodiversity: Efforts of the Indian Government -- Chapter 23. Legal Framework for Conservation of Biodiversity in India -- Chapter 24. Index.
    Abstract: This contributed book is based on the current status of biodiversity in India, issues and challenges faced by the authorities involved in conservation efforts, and the imperative role of various direct and indirect stakeholders in biodiversity conservation. The book discusses the current status of different forms of biodiversity in India, challenges faced by stakeholders, issues and reasons for biodiversity losses, and efforts by government through various laws, policies, and programs in a concise and comprehensive manner throughout its many chapters. In this way, readers can access diverse information on Indian biodiversity through this book. It is compiled by leading experts in the field of conservation. In 18 chapters, it covers biodiversity of both fauna and flora, on land and in aquatic ecosystems, legal and policy aspects, as well as innovative conservation tool and techniques. It is useful for undergraduates and graduate students and also educates policy planners, bureaucrats, foresters, and researchers in India and abroad.
    Type of Medium: Online Resource
    Pages: X, 665 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811697777
    URL: https://doi.org/10.1007/978-981-16-9777-7
    DOI: 10.1007/978-981-16-9777-7
    DDC: 577
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  • 44
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    The Systemic Effects of Advanced Cancer : A Textbook on Cancer-Associated Cachexia (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Oncology. ; Immunology. ; Metastasis. ; Cytology. ; Cancer Biology. ; Oncology. ; Immunology. ; Metastasis. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Systemic View of Metastatic Disease: Inter-organ Crosstalk and Therapeutic Implications -- Part I. Systemic Regulation in Metastatic Disease -- Chapter 2. Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles -- Chapter 3. Bone Metastasis: Systemic Regulation and Impact on Host -- Chapter 4. Targeting Metastatic Disease: Challenges and New Opportunities -- Part II. Cachexia: A Debilitating Systemic Effect of Cancer -- Chapter 5. Signaling Pathways That Promote Muscle Catabolism in Cachexia -- Chapter 6. The Role of Interleukin-6 Cytokines in Cancer Cachexia -- Chapter 7. NF-kB Signaling in the Macroenvironment of Cancer Cachexia -- Part III. Therapy-induced Muscle Wasting -- Chapter 8. Therapy-induced Toxicities Associated with the Onset of Cachexia -- Chapter 9. Bone-muscle Crosstalk in Advanced Cancer and Chemotherapy -- Part IV. Preventing and Targeting Cachexia in Cancer -- Chapter 10. New Developments in Targeting Cancer Cachexia -- Chapter 11. Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer.
    Abstract: This textbook discusses the systemic consequences of cancer, covering a range of topics from tumor-promoting systemic effects to the development of cachexia, as summarized in the introductory chapter 1. Part I of this textbook focuses on tumor-promoting systemic effects and begins with a chapter on how tumor-derived extracellular vesicles and particles lay the foundation for future metastases (Chapter 2). Chapter 3 discusses how metastatic cells that have colonized the bone impact the local bone microenvironment, neighboring muscles, and host physiology. Chapter 4 summarizes the available strategies for targeting metastatic cancer and emphasizes the need to incorporate a systemic view of the disease. Following this overview of the systemic effects of cancer progression, Part II of the textbook discusses cancer-induced cachexia, a debilitating systemic effect of advanced cancer. Chapters 5-7 examine the key signaling pathways (interleukin-6/GP130, NF-kB, and muscle proteolysis) that drive the development of cancer cachexia. Chapters 8 and 9 in Part III of this textbook explore how toxicities from anti-cancer therapy are associated with the onset of cachexia in cancer patients, and provide insight into potential approaches to simultaneously target both cancer and cachexia. Chapters 10 and 11 (Part IV) conclude this textbook by outlining promising approaches for the diagnosis and treatment of cachexia as well as strategies to prevent the development of cachexia through exercise. An understanding of the systemic effects of cancer is essential for the design of effective anti-cancer and anti-cachexia treatment strategies. As such, this textbook provides key information for both students and scientists engaged in cancer research and oncology.
    Type of Medium: Online Resource
    Pages: VI, 203 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031095184
    URL: https://doi.org/10.1007/978-3-031-09518-4
    DOI: 10.1007/978-3-031-09518-4
    DDC: 571.978
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  • 45
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    Online Resource
    Airborne Particulate Matter : Source, Chemistry and Health (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotic communities. ; Ecology . ; Environmental chemistry. ; Environmental sciences Social aspects. ; Ecosystems. ; Ecology. ; Environmental Chemistry. ; Environmental Social Sciences.
    Description / Table of Contents: 1 Introduction to Airborne Particulate Matter - Source, Chemistry and Health -- 2 Emission Sources of Particulate Matter -- 3 Geographic Distribution and Transport of Atmospheric Particulate Matter -- 4 Airborne particles in indoor and outdoor environments -- 5 High-resolution ambient record of aerosols over Delhi and associated typical health effects -- 6 Characterization of Primary and Secondary Airborne Particulate -- 7 Toxicological implications of fine particulates: sources, chemical composition and possible underlying mechanism -- 8 Bioaerosol and its impact on human health -- 9 Human Health Effects of Particulate Matter -- 10 Impacts and Responses of Particulate Matter Pollution on Vegetation -- 11 Mitigation and Management of Ambient Particulate Matter -- 12 Particulate Matter Regulatory Policies: National and Global Approach. .
    Abstract: This book is about airborne particulate matter, sources, chemistry and health and contained a complete information about their emission source, transport, atmospheric chemistry, distribution at local, regional and global levels, and their level in indoor and outdoor settings. Primary and secondary particulate matters in the ambient atmosphere also describe in detail. Analytical techniques, statistical tools and mathematical models used in airborne particulate research is also described. This book also covers the important aspects of the particulate matter chemistry in atmosphere, and their adverse impact on plant and human health. A detailed insight about the harmful impact of airborne particulate matter (biogenic and anthropogenic both) on different human system is described in detail. The toxicological significance of particulate matter on human body was also mentioned. The mitigation, management and regulatory policies to control ambient particulate matter is also provided. This book is also written in simple language with helpful photographs, diagrams, tables and flowcharts which will make the reader comfortable in understanding the concepts a more relatively easier way. Overall, the present book is a valuable tool for students working in the fields of Atmospheric Science, Environmental Science, Biological Sciences, Epidemiology and Agriculture Science. This book also a unique resource for environmental consultants, researchers, policymakers and other professionals involved in air quality, plant and human health.
    Type of Medium: Online Resource
    Pages: XIX, 314 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811653872
    URL: https://doi.org/10.1007/978-981-16-5387-2
    DOI: 10.1007/978-981-16-5387-2
    DDC: 577
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  • 46
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    Immuno-Oncology Crosstalk and Metabolism (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Tumors Immunological aspects. ; Cancer Treatment. ; Biochemistry. ; Metabolism. ; Cell biology. ; Immunology. ; Cancer Biology. ; Cancer Microenvironment. ; Tumour Immunology. ; Cancer Therapy. ; Metabolic Pathways. ; Immunology.
    Description / Table of Contents: 1 Cancer Metabolism and Aggressive Tumor Behaviour -- 2 Immune Cell Metabolism and Function -- 3 Cancer Cell Metabolism Effecting Immune function -- 4 Immune Cell Metabolites as Fuel for Cancer Cells -- 5 Immuno-Onco metabolism and Resistance to Therapy -- 6 Targeting Immuno-Onco metaolism in Cancers -- 7 Timing of the major metabolic switches in immune cell activation and differentiation during cancer development.
    Abstract: This book discusses the novel metabolic cross-talk between immune and tumor cells in the tumor microenvironment that promotes their growth and progression. It also describes deregulated metabolism in cancer cells that promotes suppressive and cancer cell-favourable microenvironment. Further, the book provides novel insights on the metabolic changes in immune cells that promote tumor cell growth and survival. In turn, it also reviews the involvement of immuno-onco metabolic cross-talk in the development of resistance to chemo-radiation therapy (CRT) in tumor cells. Lastly, it also explores the potential of immuno-oncology metabolism as a therapeutic approach against tumor cells.
    Type of Medium: Online Resource
    Pages: X, 218 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811662263
    URL: https://doi.org/10.1007/978-981-16-6226-3
    DOI: 10.1007/978-981-16-6226-3
    DDC: 571.978
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  • 47
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    Online Resource
    Hidden Pathways to Extinction (2022)
    Cham :Springer International Publishing :
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    Keywords: Ecology . ; Parasitology. ; Conservation biology. ; Environment. ; Applied ecology. ; Ecology. ; Parasitology. ; Conservation Biology. ; Conservation Biology. ; Environmental Sciences. ; Applied Ecology.
    Abstract: This book provides, for the first time, a comprehensive overview of the fundamental roles that ecological interactions play in extinction processes, bringing to light an underground of hidden pathways leading to the same dark place: biodiversity loss. We are in the midst of the sixth mass extinction. We see species declining and vanishing one after another. Poached rhinos, dolphins and whales slaughtered, pandas surviving only in captivity are strong emotional testimonials of what is happening. Yet, the main threat to natural communities may be overshadowed by the disappearance of large species, with most extinctions happening unnoticed and involving less eye-catching organisms, such as parasites and pollinators. Ecosystems hide countless, invisible wires connecting organisms in dense networks of ecological interactions. Through these networks, perturbations can propagate from one species to another, producing unpredictable effects. In worst case scenarios, the loss of one species might doom many others to extinction. Ecologists now consider such mechanisms as a fundamental – and still poorly understood - driver of the ongoing biodiversity crisis. Hidden Pathways to Extinction makes the invisible links connecting the fates of species and organisms evident, exploring why complexity can enhance ecosystem stability and yet accelerate species loss. Page after page, Strona provides convincing evidence that we are primarily responsible for the fall in biodiversity, that we are falling too, and that we need to redouble our conservation efforts now, or it won't be long before we hit the ground.
    Type of Medium: Online Resource
    Pages: IX, 237 p. 88 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030867645
    Series Statement: Fascinating Life Sciences,
    URL: https://doi.org/10.1007/978-3-030-86764-5
    DOI: 10.1007/978-3-030-86764-5
    DDC: 577
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  • 48
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    Blue-Green Infrastructure Across Asian Countries : Improving Urban Resilience and Sustainability (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Urban ecology (Biology). ; Biotic communities. ; Population biology. ; Ecology Methodology. ; Ecology. ; Urban Ecology. ; Community and Population Ecology. ; Ecological Modelling.
    Description / Table of Contents: Chapter 1. Mainstreaming Blue-Green Infrastructure for improving urban resilience and sustainability in the warming world -- Chapter 2. Regional trends in Social-Ecological Technological (SET) approaches to Sustainable Urban Planning: Focus on Asia -- Chapter 3. A Risk Assessment Approach to Urban Resilience -- Chapter 4. Promoting Blue Green Infrastructure in Urban Spaces through Citizen Science initiatives -- Chapter 5. Is Ensuring the Sustainable Implementation of BGI Possible? System Thinking of Urban Rivers as Social-Ecological Systems -- Chapter 6. Understanding Blue-Green Infrastructure through Spatial Maps: Contribution of Remote Sensing and GIS Technology -- Chapter 7. Cities and Biodiversity: Hidden Connections Between the Built Form and Life -- Chapter 8. Assessing ecological risks of urban air and water environment to analyse the scenarios for mainstreaming Nature-based Solutions: a case study of Bengaluru city, India -- Chapter 9. Do people appreciate economic value of water in Baku city of Azerbaijan? -- Chapter 10. Homegardens as sustainable urban agroforestry systems to promote household well-being in Kandy, Sri Lanka -- Chapter 11. Opportunities for Improving Urban Tree Cover - A Case Study in Kochi -- Chapter 12. Changing people-nature linkages around green infrastructure in rapidly urbanizing landscapes: the case of a protected area in Bengaluru Metropolitan Region of South India -- Chapter 13. Remodelling Urban Spaces in the Light of Blue-Green Infrastructure: A Case Study of Guwahati, India -- Chapter 14. Nature-based Solutions for the Restoration of the Abukuma River Ba-sin (Japan) after Typhoon Hagibis -- Chapter 15. Nature based solutions (NbS) for sustainable development of the resource-base and ecosystem services of marine and coastal ecosystems of India -- Chapter 16. Physical Vulnerability Assessment to Flooding of Residential Houses along the Coastal Areas in Sta. Rosa City, Laguna, Philippines -- Chapter 17. The significance of ancient water systems and the sacred groves in the landscape of Badami, Karnataka - A geospatial study -- Chapter 18. Urban Sustainability and Resilience building: Blue-Green infrastructure for air pollution abatement and realising multiple co-benefits -- Chapter 19. Disaster Risks and Resilience of Urban Bangladesh: Role of Blue Green Infrastructure -- Chapter 20. Endorsing City Biodiversity Index (CBI): Assessing Ecosystem Health in urban sprawls and Eco-DRR inclusive urban planning -- Chapter 21. Greenhouse Gas Mitigation by Integrating Waste Treatment System towards Low-Carbon City in Vietnam -- Chapter 22. The roles of non-governmental actors in facilitating urban blue-green infrastructures: A comparative review of the community initiatives in Taipei City, Taiwan -- Chapter 23. Mainstreaming blue-green infrastructure in policy and planning for urban resilience in the global south: promises and pitfalls.
    Abstract: This edited book discusses Blue-Green Infrastructure (BGI) from conception to implementation in building resilience and urban sustainability. The book emphasizes on infrastructures, institutions, and perceptions as three main pillars of implementing and managing successful BGI, with a special focus on Asia. The book highlights concepts as well as field-based experiences from different parts of Asia by experts, with a special focus on advances and opportunities in advancing BGI, challenges and constraints, followed by case studies on BGI mainstreaming. It addresses sustainable water management, multiscale environmental design, environmental risk assessment, and finally understanding policy implications and concerns for BGI mainstreaming in growing urban sprawls of the region. There has been growing global momentum and recognition of Blue-Green Infrastructure (BGI) as a multifunctional Nature-based Solution (NbS) with multiple co-benefits. There is strong evidence from many urban centres of Europe, USA, China, and South Africa demonstrating that mainstreaming BGI can help in addressing growing vulnerability of urban areas by ensuring safety, resilience, and sustainability for urban residents in the warming world. This book is a timely contribution for researchers, students, scholars, urban planners, consultants, and policy makers in the fields of environment, resilience, urban planning, climate adaptation, and sustainability science. .
    Type of Medium: Online Resource
    Pages: XXI, 518 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811671289
    URL: https://doi.org/10.1007/978-981-16-7128-9
    DOI: 10.1007/978-981-16-7128-9
    DDC: 577
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    Satoumi Science : Co-creating Social-Ecological Harmony Between Human and the Sea (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Environmental management. ; Oceanography. ; Sustainability. ; Biotic communities. ; Ecology. ; Environmental Management. ; Ocean Sciences. ; Sustainability. ; Ecosystems.
    Description / Table of Contents: Chapter 1. Prologue: What is Satoumi? -- Chapter 2. The History and Future of Satoumi Concept -- Chapter 3.Global Effect of the Satoumi Concept – Harmony of Human Society with the Ocean Biome -- Chapter 4. Roles of Women in Satoumi -- Chapter 5. Enlivening Ecosystems with Human Hands: Building Satoumi through Coral Reef Culture -- Chapter 6. Restoring Eelgrass Beds and Culturing Oysters -- Chapter 7. Reviving Abandoned Aquaculture Ponds and Coastal Areas by Integrated Multi Tropic Aquaculture -- Chapter 8. Conserving Multiple Coral Reef Resources -- Chapter 9. Villagers Managing Lake Fisheries Resources by Themselves: Mbenji Islands in Lake Malawi -- Chapter 10. Protecting Fisheries Resources through Marine Protected Area Networks – Fiji -- Chapter 11. Connecting Local Regions and Cities through Mozuku Seaweed Farming and Coral Reef Restoration: Onna Village, Okinawa -- Chapter 12. Divers and Fishermen Working Together to Create Satoumi -- Chapter 13. Models for Implementing the Satoumi Concept via Residential Research Institute Collaborations with Citizen Scientists in the United States -- Chapter 14. Epilogue: Opening the Way to Sustainable Futures with Satoumi.
    Abstract: This book guides readers to the new concept of “Satoumi” and explains how its practice works to solve challenges in complex social-ecological systems of coastal areas. The book describes the significance of Satoumi Science as a transdisciplinary process. It starts with introducing the definition of Satoumi, highlights the important distinction between active measures (direct actions to improve ecosystem functions and services) and passive measures (a variety of management activities), and presents the concept of Integrated Local Environmental Knowledge (ILEK) as a knowledge base for Satoumi activities. It also introduces residential researchers and bilateral knowledge translators as the key actors of Satoumi co-creation through the transdisciplinary processes. The concept of Satoumi goes beyond the idea of protecting pristine nature by eliminating humans. It is about creating coastal environments where humans closely connect with the sea, which leads to the effective conservation and sustainable management of various natural resources and ecosystem services. This book will be of high interest to managers, governments, environmental groups, and the research community. Chapters cover current and emerging concerns, such as over- and under-use of natural resources, restoration of damaged ecosystems, and co-creation of new relations between humans and coastal seas, from transdisciplinary approaches to tackle with complex and 'wicked' challenges of coastal social-ecological systems. .
    Type of Medium: Online Resource
    Pages: VIII, 272 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811674914
    Series Statement: Ecological Research Monographs,
    URL: https://doi.org/10.1007/978-981-16-7491-4
    DOI: 10.1007/978-981-16-7491-4
    DDC: 577
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  • 50
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    Civil Society and Peacebuilding in Sub-Saharan Africa in the Anthropocene : An Overview (2022)
    Cham :Springer International Publishing :
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    Keywords: Ecology . ; Sustainability. ; Environmental sciences Social aspects. ; Ecology. ; Sustainability. ; Environmental Social Sciences.
    Description / Table of Contents: 1 General Introduction -- 2 Peace Ecology in the Anthropocene for Africa -- 3 Civil Society, Climate Change, Security Risks Management and Peacebuilding in the Anthropocene -- 4 Faith-based Organisations and Environmental Peace: Impact of Laudato Si’ and Its Relevance in the Anthropocene -- 5 Healing Nature and Creation in the Anthropocene: A Reflection on the Role of Religion -- 6 Empowering Women to Build Peace: A Case Study of Grace to Heal Trust in Lupane District -- 7 Peacebuilding through Indigenous Knowledge Systems: Lessons from Civil Society Organisations in Zimbabwe -- 8 Civil Society and Peacebuilding in the Kivu Provinces of the Democratic Republic of Congo -- 9 Zimbabwe’s National Peace and Reconciliation Commission and Civil Society: Partners in Peacebuilding? -- 10 Civil Society and Peacebuilding in the Democratic Republic of Congo: Opportunities, Challenges and Recommendations -- 11 Promoting Democratisation in DR Congo: The Case Study of Act for Transparent and Peaceful Elections -- 12 Civil Society Organisations and School Peace Clubs in South Africa: An Outcome Evaluation -- 13 The Challenges and Opportunities for Civil Society in Peacebuilding: Lessons from the Matabeleland Collective, Zimbabwe -- 14 The Role of Civil Society Participation in Social Cohesion Processes in KwaZulu-Natal, South Africa.-15 Building the Capacity of Civil Society Organisations in Nonviolent Campaigning: A Case Study from South Sudan -- 16 How Informal Peace Committees Complement Macro-infrastructures for Peace in Zimbabwe -- 17 Protecting and Nurturing Children Born from Rape in South Kivu Communities: A Challenge for Civil Society -- 18 Indigenous Peacebuilding Approaches and the Accountability of Former Child Soldiers: African Case Studies -- 19 Navigating Channels for Civil Society Participation in Conflict Prevention and Peace-Making in the African Peace & Security Architecture -- 20 Centre-periphery Relations Between Civil Society Organisations and External Funding Partners: A Case Study of South Kivu’s Peace and Development Agenda. .
    Abstract: This book examines civil society's peacebuilding role in sub-Saharan Africa in the context of climate change and the pursuit of environmental peace and justice in the Anthropocene. Five main research themes emerge from its 20 chapters: · The roles of environmental peacemaking, environmental justice, ecological education and eco-ethics in helping to mitigate the impacts of climate change · Peacebuilding by CSOs after violent conflicts, with particular reference to accountability, reconciliation and healing · CSO involvement in democratic processes and political transition after violent conflicts · Relationships between local CSOs and their foreign funders and the interactions between CSOs and the African Union's peace and security architecture. · The particular role of faith-based CSOs The book underlines the centrality of dialogue to African peacebuilding and the indigenous wisdom and philosophies on which it is based. Such wisdom will be a key resource in confronting the existential challenges of the Anthropocene. The book will be a significant resource for researchers, academics and policymakers concerned with the challenge of climate change, its interactions with armed conflict and the peacebuilding role of CSOs. · This pathbreaking book shows why peacebuilding analysis and efforts need to be urgently re-oriented towards the existential challenges of environmental peace and justice. · It explains the emerging conceptual frameworks which are needed for this new role. · It explains the critical role that CSOs - local and international - will play in implementing this new peacebuilding approach, with particular reference to sub- Saharan Africa.
    Type of Medium: Online Resource
    Pages: XXXVI, 580 p. 43 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030951795
    Series Statement: The Anthropocene: Politik—Economics—Society—Science, 34
    URL: https://doi.org/10.1007/978-3-030-95179-5
    DOI: 10.1007/978-3-030-95179-5
    DDC: 577
    Language: English
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    Online Resource
    Disturbance Ecology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Landscape ecology. ; Plant ecology. ; Ecology. ; Landscape Ecology. ; Plant Ecology. ; Terrestial Ecology.
    Description / Table of Contents: Chap 1: Disturbance ecology: a guideline -- Chap 2: Definitions and quantifications -- Chap 3: Concepts -- Chap 4: Abiotic disturbances -- Chap 5: Biotic disturbances -- Chap 6: Anthropogenic disturbances -- Chap 7: Disturbances in global change -- Chap 8: Disturbances and management.
    Abstract: This edited work presents a multi-faceted view on the causes and consequences of disturbance in ecosystems. Vegetation can be affected by a variety of different disturbances such as wind, floods, fire, and insect attack, leading to an abrupt change in live biomass. Disturbance is a motor of vegetation dynamics, but also sensitive to climate change and poses a challenge for ecosystem management. Readers will discover the global distribution of disturbance regimes and learn about the importance of disturbances for biodiversity and the evolution of plant and animal life. The book provides a Central European perspective on disturbance ecology, and addresses important disturbance agents such as fire, wind, avalanches, tree diseases, insect defoliators, bark beetles and large herbivores in dedicated chapters. It furthermore includes chapters on anthropogenic disturbances in forests and grasslands. The impact of climate change on disturbance regimes and approaches to address disturbance risks in ecosystem management are discussed in concluding chapters. Within the 18 chapters 14 textboxes highlight current topics of disturbance ecology and provide deeper methodological insights into the field. Disturbances strongly shape our landscapes and maintain our biodiversity. A better understanding of their ecology is thus fundamental for contextualizing the dynamic changes in our environment. This book is a valuable resource for students and practitioners interested in disturbances and their management.
    Type of Medium: Online Resource
    Pages: XI, 439 p. 153 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030987565
    Series Statement: Landscape Series, 32
    URL: https://doi.org/10.1007/978-3-030-98756-5
    DOI: 10.1007/978-3-030-98756-5
    DDC: 577
    Language: English
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  • 52
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    Cancer Metastasis Through the Lymphovascular System (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Metastasis. ; Lymphatics. ; Cancer Biology. ; Metastasis. ; Lymphatic System.
    Description / Table of Contents: Section 1: Genetic and Molecular Pathways of Cancer Growth and Metastasis -- Chapter 1. Hallmarks of Cancer: Molecular Underpinnings -- Chapter 2. Unifying concept of genomic changes: The mutational landscape of cancers -- Chapter 3. Tumor Microenvironment: Coconspirator in Tumorigenesis -- Chapter 4. Hallmarks of Metastasis: Molecular Underpinnings -- Chapter 5. Hereditary Cancer Syndromes and Cancer Metastasis -- Section 2: Pathology of Cancer Growth and Metastasis -- Chapter 6. Pathologic Assessment of Lymph Node Metastasis -- Chapter 7. Pathologic Assessment of Systemic or Distant Metastasis -- Chapter 8. The Role of Angiotropic Extravascular Migratory Metastasis in Metastases -- Section 3: Dormant Cancer Cells and their Reactivation in the Host Cancer Microenvironment -- Chapter 9. Tumor Dormancy and Relapse Regulated by the Extracellular Matrix -- Chapter 10. Therapy-Induced Dormancy and Residual Disease -- Section 4: The Microenvironment of Site-Specific Metastasis - Isaac P. Witz -- Chapter 11. The Microenvironment of Site-Specific Metastasis -- Section 5: Circulating Cancer Cells and Liquid Biopsy -- Chapter 12. Circulating tumor cells and ctDNA in sarcomas -- Chapter 13. Liquid biopsy using cell-free tumor DNA for gastrointestinal cancers -- Chapter 14. Circulating tumor cells and ctDNA in prostate cancer.-Chapter 15. Circulating Tumor Cells in Lung Cancer -- Chapter 16. CTCs/ ctDNA and Brain Metastasis.-Chapter 17. Epigenetics and liquid biopsy in oncology: role in metastasis and clinical utility -- Chapter 18. Metabolic reprogramming of circulating tumor cells for metastasis -- Section 6: Lymphatic System and Cancer Metastasis -- Chapter 19. Lymphatic System Biology, Pathobiology, and Relation to Cancer Metastasis -- Chapter 20. Lymphatic Specification and Development, EMT-MET, and Cancer Spread -- Chapter 21. Lymphangiogenesis, Lymph Nodes, Cancer Lymphangiogenesis and Metastasis -- Chapter 22. Immune cell trafficking in the lymphatics, hyaluronan biology and tumour metastasis -- Chapter 23. Lymphvascular Genomics and Proteomics, Clinical Syndromes, and Cancer Metastasis -- Chapter 24. Imaging of the Lymphatic System with Relevance to Cancer and Cancer Metastasis -- Chapter 25. Lymphedema: general pathophysiology, prevention and management in invasive cancer -- Section 7: Radiological Imaging of Early Cancer and Cancer Metastases -- Chapter 26. Primary Tumor Staging and Detection of Common Sites of Distant Metastatic Disease -- Chapter 27. Imaging Modalities in the Detection and Diagnosis of Metastatic Disease -- Chapter 28. Imaging of Bone Metastases -- Chapter 29. Imaging of Lung and Soft Tissue Metastases -- Chapter 30. Image-Guided Biopsy and Intervention for Metastatic Disease -- Section 8: Sentinel Lymph Node Surgery for Solid Cancer. Chapter 31. Sentinel Lymph Node Biopsy for Primary Cutaneous Malignancy -- Chapter 32. Sentinel Lymph Node Biopsy in Breast Cancer -- Chapter 33. Sentinel node navigation surgery for upper gastrointestinal cancer -- Chapter 34. Sentinel Lymph Node Mapping in Non-Small Cell Lung, Colon, and Thyroid Carcinomas -- Section 9: Surgical Treatment of Primary and Metastatic Cancer -- Chapter 35. The efficacy and evolution of surgical management based on cancer biology -- Chapter 36. The role of surgery in managing primary and metastatic melanoma -- Chapter 37. The Role of Surgery in Managing Primary and Metastatic Breast Cancer -- Chapter 38. The role of surgery in managing primary and metastatic colorectal cancer -- Chapter 39. The Role of Surgery in Management of Gastric Cancer -- Chapter 40. The role of surgery in managing primary and metastatic hepatopancreaticobiliary cancers -- Section 10: Cancer Metastasis to the Lung -- Chapter 41. Metastatic disease of the lung -- Section 11: Cancer Metastasis to the Liver -- Chapter 42. Tumor Resection and Ablation as a Means of Controlling Hepatic Metastases -- Chapter 43. Regional Arterial Infusional Therapy as a Means of Controlling Hepatic Metastases -- Section 12: Cancer Metastasis to the Bone -- Chapter 44. Molecular Mechanisms of Metastasis to the Bone.-Chapter 45. Surgical Management of Metastatic Disease to the Upper Extremity -- Chapter 46. Surgical Management of Metastatic Disease to the Lower Extremity -- Chapter 47. Surgical management of metastatic disease to the pelvis -- Chapter 48. Surgical Management of Metastatic Disease to the Spine -- Chapter 49. Interventional radiology techniques for management of skeletal metastases -- Section 13: Cancer Metastasis to the Brain and the Nervous System -- Chapter 50. Brain Metastases: Overview and Molecular Mechanisms -- Chapter 51. Indications and Techniques for Surgical Intervention in Patients with Metastatic Brain Tumors -- Chapter 52. Brain Metastases: Current and Future pharmacological treatment -- Chapter 53. Radiotherapy for CNS Metastases -- Chapter 54. Leptomeningeal Carcinomatoses -- Section 14: Urologic Cancer and 1st Patterns of Metastasis -- Chapter 55. Urologic Cancer and 1st Patterns of Metastasis -- Section 15: Biology and Clinical Aspects of Sarcoma Progression -- Chapter 56. Soft Tissue Sarcoma -- Chapter 57. Bone Sarcoma -- Chapter 58. Liposarcoma Metastasis -- Chapter 59. Desmoid Tumors.-Chapter 60. Atypical patterns of metastases: How do Sarcoma’s metastasize? -- Chapter 61. Tumor Immune Microenvironment of Soft Tissue Sarcoma -- Section 16: The Role of Radiation in the Treatment of Primary and Metastatic Cancer -- Chapter 62. Basic Principles of Radiobiology and Cancer Metastasis Prevention -- Chapter 63. Technical Innovations in the Delivery of Radiation Therapy -- Chapter 64. Radiation Therapy in the Definitive Treatment of Cancer -- Chapter 65. Radiation Therapy for Extracranial Oligometastatic Disease -- Chapter 66. Spine Radiotherapy -- Section 17: Immunotherapy of Solid Malignancies -- Chapter 67. Immunotherapy in Melanoma and Merkel Cell Cancer -- Chapter 68. Landscape of Immunotherapy in Lung Cancer -- Chapter 69. Immuno-oncologic Treatment of Genitourinary Malignancies -- Section 18: Current Topics -- Chapter 70. Personalized Systemic Cancer Therapy -- Chapter 71. Cancer Stem Cells and Their Role in Metastasis -- Chapter 72. HPV Induced Cancers -- Chapter 73. Microbiome and Cancer Metastasis -- Chapter 74. Application of Artificial Intelligence in Research on Cancer and Its Metastasis.
    Abstract: This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. .
    Type of Medium: Online Resource
    Pages: XXIV, 806 p. 145 illus., 106 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030930844
    URL: https://doi.org/10.1007/978-3-030-93084-4
    DOI: 10.1007/978-3-030-93084-4
    DDC: 571.978
    Language: English
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    Systems Biology of MicroRNAs in Cancer (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Tumor markers. ; Non-coding RNA. ; Cancers. ; Tumour Biomarkers. ; Non-coding RNAs.
    Description / Table of Contents: Chapter 1. The Role of MicroRNAs in Cancer Biology and Therapy from a Systems Biology Perspective -- Chapter 2. Circulating MicroRNAs as Cancer Biomarkers in Liquid Biopsies -- Chapter 3. Regulation of Immune Cells by MicroRNAs and MicroRNA-Based Cancer Immunotherapy -- Chapter 4. Machine-Learning-Based Methods and Best Practices of MicroRNA-Target Prediction and Validation -- Chapter 5. Turning Data to Knowledge: Online Tools, Databases and Resources in MicroRNA Research -- Chapter 6. Bioinformatics Methods for Modeling MicroRNA Regulatory Networks in Cancer -- Chapter 7. Analysis of the p53/MicroRNA Network in Cancer -- Chapter 8. Machine Learning Using Gene-Sets to Infer miRNA Function -- Chapter 9. miRNA:miRNA Interactions: A Novel Mode of miRNA Regulation and Its Effect on Disease -- Chapter 10. ClustMMRA v2: A Scalable Computational Pipeline for the Identification of MicroRNA Clusters Acting Cooperatively on Tumor Molecular Subgroups -- Chapter 11. 3D Modeling of Non-coding RNA Interactions.
    Abstract: This book provides an update on the latest development in the field of microRNAs in cancer research with an emphasis on translational research. Since the early 2000s, microRNAs have been recognized as important and ubiquitous regulators of gene expression. Soon it became evident that their deregulation can cause human diseases including cancer. This book focuses on the emerging opportunities for the application of microRNA research in clinical practice. In this context, computer models are presented that can help to identify novel biomarkers, e.g. in circulating microRNAs, and tools that can help to design microRNA-based therapeutic interventions. Other chapters evaluate the role of microRNAs in immunotherapy, immune responses and drug resistance. Covering key topics on microRNAs in cancer research this book is a valuable resource for both emerging and established microRNA researchers who want to explore the potential of microRNAs as therapeutic targets or co-adjuvants in cancer therapies.
    Type of Medium: Online Resource
    Pages: VII, 317 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031083563
    Series Statement: Advances in Experimental Medicine and Biology, 1385
    URL: https://doi.org/10.1007/978-3-031-08356-3
    DOI: 10.1007/978-3-031-08356-3
    DDC: 571.978
    Language: English
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    Sika Deer: Life History Plasticity and Management (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Animal culture. ; Environmental management. ; Population biology. ; Evolution (Biology). ; Conservation biology. ; Ecology. ; Animal Science. ; Environmental Management. ; Population Dynamics. ; Evolutionary Biology. ; Conservation Biology.
    Description / Table of Contents: 1.Introduction -- 2. The Process of Population Expansion of Sika Deer -- 3. The Impact of Sika Deer on Vegetation in Japan -- 4.Estimation of Sika Deer Abundance by Harvest-based Model and the Characteristics of their Population Dynamics -- 5. Variation in the local sika deer density between three areas of Japan with diverse climatic conditions -- 6. Ecological and evolutionary response of sika deer morphology to varying habitat environments: from body size to tooth wear -- 7. Reproductive variation of sika deer -- 8. Movement Patterns of Sika Deer in Hokkaido Region -- 9. Movement Patterns of Sika Deer in Tohoku Region -- 10. Movement patterns of sika deer in the mountainous regions of central Honshu -- 11. Movement Characteristics and Habitat Use of Sika Deer in Kanto Region, Central Japan -- 11. Movement patterns and activity range characteristics of sika deer in the Tanzawa Mountains, central Japan -- 13. Movement patterns of sika deer around Mt. Fuji, central Japan -- 14. Movement Patterns of Sika deer in Western Japan -- 15. Behavior of sika deer in clear-cut areas, plantations, and their surroundings -- 16. Effects of high densities of sika deer on vegetation and the restoration goal: Lessons from deer-vegetation interactions on Nakanoshima Island, Lake Toya -- 17. Irruptive Dynamics of Sika Deer: Search for the Mechanism -- 18. Food habits and body condition of the sika deer population in the Tanzawa Mountains, central Japans -- 19. Effects of sika deer and the unique relationship with forest vegetation in Yakushima Island -- 20. Conserving The Plant Community and Its Resilience Using Deer-Proof Fences in Japan -- 21. Vertebrate Scavenging on Sika Deer Carcasses and Its Effects on Ecological Processes -- 22. Impacts of Sika Deer Overabundance on The Structure and Functions of Dung Beetle Communities in Forest Ecosystems -- 23. Impact of Sika Deer on Soil Properties and Erosion -- 24. Responses of Ground-layer Vegetation and Soil Properties to Increased Population Density of Sika Deer and Environmental Conditions -- 25. Successional Pathways of a Warm-Temperate Forest After Disturbance: Effects of Clearcutting and Herbivory -- 26. Effect of Different Periods of Chronic Deer Herbivory on both Tall Forbs and Soil Seed Banks Following Deer Exclusions in a Damp Beech Forest -- 27. Indirect effects of deer overgrazing on stream ecosystems -- 28. Activity Patterns and Habitat Use Between Sika Deer and Japanese Serow -- 29. Sika in the British Isles: Population Ecology -- 30. History and Management of Sika Deer on the Delmarva Peninsula -- 31. The future of sika deer management in New Zealand; Invasive deer or hunting resource? -- 32. Adaptive Management of Sika Deer Populations on Hokkaido Island, Japan -- 34.Adaptive Management of Sika Deer in Hyogo Prefecture -- 35.Subpopulation Structure Based on Landscape Genetics as a Management Unit -- 36. Future Challenges for Research and Management of Sika Deer.
    Abstract: This book provides complete and up-to-date information on sika deer biology and its management, focusing on their life history with an integrated approach of population dynamics, morphology, genetics, and evolution. The expanding distribution of sika and its increase in population in Japan and other countries are causing damage to agriculture and forestry, impacting ecosystems and affecting other species. We are facing conflicting deer issues regarding the conservation of resource values and pest control of sika deer. This contributed volume compiles new findings focusing on the ecological plasticity of the sika deer. It aims to clarify the ecological characteristics of the deer by integrating studies of different approaches and provides a perspective for their management. The book consists of six parts. Part I introduces the ecological and management background behind the history of sika deer. The following four parts discuss movement ecology (Part II), impact on vegetation and bottom-up effect on sika deer (Part III), impact on ecosystem and its resilience (Part IV), and comparison of life-history characteristics between sika deer and other ungulate species (Part V). The last part (Part VI) covers the science-based management of sika deer. Contributed by recognized experts and young researchers of sika deer, this book appeals to researchers and professionals in wildlife biology and wildlife management, evolution, population dynamics, morphology, genetics, and reproductive physiology. .
    Type of Medium: Online Resource
    Pages: XII, 641 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811695544
    Series Statement: Ecological Research Monographs,
    URL: https://doi.org/10.1007/978-981-16-9554-4
    DOI: 10.1007/978-981-16-9554-4
    DDC: 577
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  • 55
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    The Extracellular Matrix and the Tumor Microenvironment (2022)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Cytology. ; Clinical biochemistry. ; Cancer Biology. ; Cell Biology. ; Medical Biochemistry.
    Description / Table of Contents: Chapter 1: Small leucine-rich proteoglycans regulate cancer cell growth, apoptosis-and associated inflammation -- Chapter 2: The role of decorin in cancer -- Chapter 3: The mystery of syndecan-1 in tumor development and progression -- Chapter 4:Syndecan-2 Biology and its Role in Colorectal Carcinoma -- Chapter 5: Versican in Tumor Progression, Tumor-Host Interactions and Cancer Immunotherapy -- Chapter 6:Circulating proteoglycans/glycosaminoglycans as cancer biomarkers -- Chapter 7: Hyaluronan in the Extracellular Matrix of hematological and solid tumors. Its biological effects" -- Chapter 8: Heparanase: a paramount enzyme for cancer initiation, progression and metastasis -- Chapter 9: Laminins and matrix metalloproteinases connection: a subtle relationship that can go wrong in a tumor context, particularly if CD44 gets involved -- Chapter 10:Basement membrane, collagen, and fibronectin: physical interactions with cancer cells -- Chapter 11: Integrins in cancer: re-focusing on the tumor microenvironment -- Chapter 12: Adipose compounds in breast tumor extracellular matrix -- Chapter 13: Extracellular matrix as a metabolic niche in cancer -- Chapter 14: The role of inflammatory cells in tumor angiogenesis -- Chapter 15: Cancer angiogenesis and its master regulator perlecan -- Chapter 16: The microRNA-extracellular matrix interplay in breast cancer -- Chapter 17: The impact of the extracellular matrix on immunotherapy success -- Chapter 18: Exploiting hyaluronan-CD44 network in tumor therapy.
    Abstract: This book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression. Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression. Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM. This book is an interesting read for anyone who want to know more about ECM and cancer biology. Early career scientists can use it as an introduction to the field, offering an excellent tool for studying ECM. Advanced researchers and clinicians can gain a broader overview of the subject, considering the role of ECM for influencing every cancer hallmark as well as in the response of cancer treatments. The work serves to inspire future research and shows that the ECM should be considered as an important factor in the development of cancer therapeutics. The series "Biology of Extracellular Matrix" is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
    Type of Medium: Online Resource
    Pages: X, 494 p. 40 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030997083
    Series Statement: Biology of Extracellular Matrix, 11
    URL: https://doi.org/10.1007/978-3-030-99708-3
    DOI: 10.1007/978-3-030-99708-3
    DDC: 571.978
    Language: English
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    Breast Cancer: From Bench to Personalized Medicine (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Cancer Epidemiology. ; Cancer Genetic aspects. ; Cancer Biology. ; Cancer Epidemiology. ; Cancer Genetics and Genomics.
    Description / Table of Contents: Module 1_Overview of Breast Cancer -- Module 2_Cell and Molecular Biology of Breast Cancer-Diagnosis and Prognosis -- Module 3_Breast Cancer Treatment.
    Abstract: This book provides detailed information on the etiology, pathogenesis, diagnosis, prognosis, and treatment strategies for breast cancer. The first section of the book presents epidemiology, risk factors, histopathological, immunohistochemistry, and molecular subtypes of breast cancer based on the receptor status. It also discusses the association of breast cancer with other hormone-sensitive cancers. The second section of the book covers cover BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression of breast cancer, and noninvasive biomarkers for the early detection of breast cancer. It also discusses the role of epigenetic modifications and non-coding RNAs in breast cancer metastasis and explores these as the biomarkers and therapeutic targets for breast cancer therapy. Further, it discusses the role of fibrinolytic mechanisms and circulating tumor cells in breast cancer diagnosis, prognosis, and treatment. The book also provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors to treat breast cancer. Finally, it offers potential new options for personalized therapies for breast cancer patients, including optimizing drug dosage and identifying genetic changes associated with cancer symptom occurrence and severity.
    Type of Medium: Online Resource
    Pages: XVII, 536 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811901973
    URL: https://doi.org/10.1007/978-981-19-0197-3
    DOI: 10.1007/978-981-19-0197-3
    DDC: 571.978
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  • 57
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    Green Infrastructure and Climate Change Adaptation : Function, Implementation and Governance (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotic communities. ; Landscape ecology. ; Environmental economics. ; Forestry. ; Bioclimatology. ; Ecosystems. ; Landscape Ecology. ; Environmental Economics. ; Forestry. ; Climate Change Ecology.
    Description / Table of Contents: Chapter 1: Introduction -- Part 1: Concept and synthesis -- Chapter 2: Concept and application of hybrid infrastructure -- Chapter 3: An Economic Analysis of Optimal Hybrid Infrastructure: A Theoretical Approach in a Hydro-Economic Model -- Chapter 4: Flood Management Policy in Shiga Prefecture, Japan: Implementation Approach of a Risk-Based Flood Management System at Catchment Scale -- Chapter 5: Toward social infrastructure: typological idea for evaluating implementation potential of green infrastructure -- Part 2 : Forest ecosystem -- Chapter 6: Riparian Forests and Climate Change: Interactive Zone of Green and Blue Infrastructure -- Chapter 7: Improvement of the flood-reduction function of forests based on their interception evaporation and surface storage capacities -- Chapter 8: Forests for water: A step-by-step guide for payment schemes -- Part 3: River and floodplain ecosystem (including paddy field and other farmlands) -- Chapter 9: Wetland Paddy Fields as Green Infrastructure against Flood -- Chapter 10: Change in Floodwater Retention Function of a Paddy Field due to Cultivation Abandonment in a Depopulating Rural Region in Japan -- Chapter 11: Paddy field as a green inflastructure: their ecosystem services and threatening drivers -- Part 4: Wetland ecosystem (including flood-control pond) -- Chapter 12: Flood-control basins as green infrastructures: flood-risk reduction, biodiversity conservation and sustainable management in Japan -- Chapter 13: Natural Succession of Wetland Vegetation in a Flood-control Pond Constructed on Abandoned Farmland -- Chapter 14: Biodiversity Conservation through Various Citizen Activities in a Flood Control Basin -- Part 5: Urban and city ecosystem -- Chapter 15: Toward holistic Urban Green Infrastructure Implementation -- Chapter 16: Changes in the Use of Green Spaces by Citizens before and during the First COVID-19 Pandemic: A Big data analysis using mobile-tracking GPS data in Kanazawa, Japan -- Chapter 17: Land Use Planning as a Green Infrastructure in a Rural Japanese Depopulated Town -- Chapter 16: Towards an Equitable Distribution of Urban Green Spaces for People and Landscapes; An opportunity for Portland's Green Grid -- Part 6: Coast and estuary ecosystem -- Chapter 19: "Effectiveness and Sustainability of Coastal Hybrid Infrastructures for Low-Frequency Large-Scale Disasters -- A Case Study of Coastal Disaster Assessment for a Complex Disaster" -- Chapter 20: Challenging a Hybrid between Green and Gray Infrastructure – Coastal Sand-covered Embankments -- Chapter 21: Green Infrastructures in Megacity Jakarta: Current Status and Possibilities of Mangroves for Flood Damage Mitigation -- Chapter 22: Implementation of Japanese Blue Carbon Offset Crediting Projects -- Part 7: Economic evaluation -- Chapter 23: Understanding Preference Differences among Individuals for the Reduction in Flood Risk by Green Infrastructure -- Chapter 24: Assessing Public Preference for Construction of Giant Seawalls Using the Best–Worst Scaling Approach -- Chapter 25: "Coastal communities’ preferences of grey, green and hybrid infrastructure against unexpected catastrophes: A case study of Japan" -- Chapter 26: Carbon storage and substitution benefits of harvested wood products -- Part 8: Governance -- Chapter 27: Social System in Collaborative Activities for Conserving Coastal Pine Forest in Karatsu City, Kyusyu, Japan -- Chapter 28: Governance for realizing multifunctional floodplain; flood control, agriculture, and biodiversity in Yolo Bypass Wildlife Area, California, USA -- Chapter 29: Analysis of the description of the multifunctionality of farmland in the administrative plans of local municipalities.
    Abstract: This open access book introduces the function, implementation and governance of green infrastructure in Japan and other countries where lands are geologically fragile and climatologically susceptible to climate change. It proposes green infrastructure as an adaptation strategy for climate change and biodiversity conservation. In the face of climate change, dams, levees and floodways built as disaster prevention facilities do not sufficiently function against extraordinary events such as mega-floods and tsunami disasters. To prevent those disasters and loss of biodiversity in various ecosystems, we should shift from conventional hard measures to more adaptive strategies using various functions that natural and semi-natural ecosystems provide. Green infrastructure is an interconnected network of waterways, wetlands, woodlands, wildlife habitats and other natural areas that support native species, maintain natural ecological processes, sustain air and water resources and contribute to the health and quality of life for communities and people. Green infrastructure has mainly been discussed from adaptation strategy perspectives in cities and urban areas. However, to protect cities, which are generally situated at downstream lower elevations, we explore the preservation and restoration of forests at headwater basins and wetlands along rivers from a catchment perspective. In addition, the quantitative examination of flood risk, biodiversity, and social-economic benefits described in this book brings new perspectives to the discussion. The aim of this book is to accelerate the transformative changes from gray-based adaptation strategies to green- or hybrid-based strategies to adapt to climate change. The book provides essential information on the structure, function, and maintenance of green infrastructure for scientists, university students, government officers, and practitioners.
    Type of Medium: Online Resource
    Pages: XII, 506 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811667916
    Series Statement: Ecological Research Monographs,
    URL: https://doi.org/10.1007/978-981-16-6791-6
    DOI: 10.1007/978-981-16-6791-6
    DDC: 577
    Language: English
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    Biology and Ecology of Earthworms (2022)
    New York, NY :Springer US :
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    Keywords: Ecology . ; Environmental management. ; Refuse and refuse disposal. ; Zoology. ; Ecology. ; Ecology. ; Environmental Management. ; Waste Management/Waste Technology. ; Zoology.
    Description / Table of Contents: Ch. 1. Earthworm Morphology -- Ch. 2. Earthworm Physiology -- Ch. 3. Earthworm Diversity, Dispersal, and Geographical Distribution -- Ch. 4. Earthworm Life Histories and Biology -- Ch. 5. Earthworm Ecology: Populations -- Ch. 6. Earthworm Ecology: Communities -- Ch. 7. The Influence of Environmental Factors on Earthworms -- Ch. 8. The Role of Earthworms in Organic Material and Nutrient Cycles -- Ch. 9 -- Interactions Between Earthworms, Microorganisms, and Other Invertebrates -- Ch. 10. Role of Earthworms in Soil Structure, Fertility and Productivity -- Ch.11. Adverse and Beneficial Aspects of Earthworms -- Ch. 12. Earthworms in Environmental Management -- Ch.13. Earthworms in Organic Waste Management -- Ch.14. Effects of Agricultural Practices and Chemicals on Earthworms. .
    Abstract: Biology and Ecology of Earthworms is established as a key valuable text for students of agriculture, soil science, and soil invertebrate zoology and ecology. This is the 4th Edition of the popular textbook which reviews all aspects of earthworm biology and ecology. The book has been fully revised and updated throughout. Particular changes include: new treatments of earthworm taxonomy, diversity, migration and geographical distribution; interactions between earthworms and other soil organisms, especially microorganisms and soil-borne pests and diseases; as well as the importance of earthworms in organic waste management.
    Type of Medium: Online Resource
    Pages: XVI, 567 p. 92 illus., 11 illus. in color. , online resource.
    Edition: 4th ed. 2022.
    ISBN: 9780387749433
    URL: https://doi.org/10.1007/978-0-387-74943-3
    DOI: 10.1007/978-0-387-74943-3
    DDC: 577
    Language: English
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    Human-Nature Interactions : Exploring Nature’s Values Across Landscapes (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Biodiversity. ; Geography. ; Environmental management. ; Ecosystems. ; Biodiversity. ; Regional Geography. ; Environmental Management.
    Description / Table of Contents: Part I: Conceptualizing human-nature interactions -- Chapter 1. Conceptualizing human-nature interactions – an overview -- Chapter 2. Environmental Values and Nature’s Contributions to People: Towards methodological pluralism in evaluation of sustainable ecosystem services -- Chapter 3. Disentangling trade-offs between the state of coastal ecosystems with human well-being and activities as a strategy addressing sustainable tourism -- Chapter 4. From human-nature dualism towards more integration in socio-ecosystems studies -- Chapter 5. A network approach to Green Infrastructure: how to enhance ecosystem services provision? -- Chapter 6. Transformations of urban coastal nature(s): Meanings and paradoxes of Blue Urbanism and nature-based solutions for climate adaptation in Southeast Asia -- Part II: Mountain systems -- Chapter 7. Values of mountain landscapes: Insights about the Blue Mountains National Park, Australia from Twitter -- Chapter 8. Earth observations of human-nature interactions from a cultural ecosystem service perspective -- Chapter 9. Gendered Values, Roles, and Challenges for Sustainable Provision of Forest-based Ecosystem Services in Nepal -- Chapter 10. Environmental [in]equity: Accessibility to green spaces in a rapidly urbanizing mountain-city -- Chapter 11. Ecosystem services and sustainable development in the European Alps: spatial patterns and mountain-lowland relationships -- Chapter 12. Human-nature relationships for the Flathead Wild and Scenic River System: Analyzing diversity, synergies, and tensions in a mountainous region of Montana, USA -- Chapter 13. Resilience and sustainability of the Maloti-Drakensberg mountain system: a case study on the upper uThukela catchment -- Chapter 14. Invasive alien plants in the montane areas of South Africa: impacts and management options -- Part III: Urban systems -- Chapter 15. Ecosystem service flows across the rural-urban spectrum -- Chapter 16. A typology for green infrastructure planning to enhance multifunctionality incorporating peri-urban agricultural land -- Chapter 17. Urban green spaces in a post-apartheid city: challenges and opportunities for nature-based solutions -- Chapter 18. Green infrastructure and ecosystem services within spatial structure of city – examples from Poznań, Poland -- Chapter 19. Accessibility to and fragmentation of urban green infrastructure: importance for adaptation to climate change -- Chapter 20. Social Demand for Urban Wilderness in Purgatory -- Chapter 21. The Role of Allotment Gardens for Connecting Nature and People -- Chapter 22. Green spaces and their social functions: specific challenges in urban spaces of arrival -- Chapter 23. The link between urban green space planning tools and distributive, procedural and recognition justice -- Part IV: Coastal-marine systems -- Chapter 24. Can local knowledge of Small-scale fishers be used to monitor and assess changes in marine ecosystems in a European context? -- Chapter 25. Marine ecological democracy: participatory marine planning in Indigenous marine areas in Chile -- Chapter 26. The Socio-Ecological Dimension of Ocean Multi-Use -- Chapter 27. Localizing the Sustainable Development Goals for marine and coastal management in Norway: A venture overdue -- Chapter 28. Coastal-Marine ecosystem accounting to support Integrated Coastal Zone Management -- Chapter 29. Exposure of coastal ecosystem services to natural hazards in the Bangladesh coast -- Chapter 30. Adaptations to climate variability in fisheries and aquaculture social-ecological systems in the Northern Humboldt Current Ecosystem: challenges and solutions -- Chapter 31. Socio-Ecological transformations in coastal wetlands: an approach from the south-central zone of Chile -- Chapter 32. A Nature-based Solution for coastal foredune restoration: The Case Study of Maghery, County Donegal, Ireland.
    Abstract: This edited volume aims to widen the discussion about the diversity of human-nature relationships and valuation methods and to stimulate new perspective that are needed to build a more sustainable future, especially in face of ongoing socio-environmental changes. Conceptual and empirical approaches, including qualitative, quantitative, and mixed methodologies have been used to highlight the importance of an integrative understanding of socio-ecological systems, where healthy ecosystems underpin the quality of life and societal activities largely drive environmental changes. Readers will obtain a comprehensive overview of the many and diverse ways the relationships between people and nature can be characterized. This includes understanding how people assign values to nature, discuss how human-nature interactions are shaped and provide examples of how these values and interactions can be systematically assessed across different land systems in Europe and beyond. This open access book is produced by internationally recognized scientists in the field but written in an accessible format to be of interest to a large audience, including prospective students, lecturers, young professionals and scientists embarking to the interdisciplinary field of socio-ecological research and environmental valuation.
    Type of Medium: Online Resource
    Pages: XVIII, 438 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031019807
    URL: https://doi.org/10.1007/978-3-031-01980-7
    DOI: 10.1007/978-3-031-01980-7
    DDC: 577
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    Evolution from a Thermodynamic Perspective : Implications for Species Conservation and Agricultural Sustainability (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Evolution (Biology). ; Ecology Methodology. ; Agriculture. ; Thermodynamics. ; Conservation biology. ; Evolutionary Ecology. ; Ecological Modelling. ; Agriculture. ; Evolutionary Biology. ; Thermodynamics. ; Conservation Biology.
    Description / Table of Contents: C ontents -- Part 1. Theory -- To Understand Economics, Follow the Money: To Understand Ecosystems, Follow the Energy -- Two Views of Ecology, Evolution, and Conservation -- Why I Wrote this Book -- Dualities Still Impede Conservation Efforts -- The Intergovernmental Science-Policy Platform of Biodiversity -- Targets for Conservation -- Evolving Objectives -- Literature Review -- Updating Ecosystem Ecology -- References -- What Can We Learn by Studying Ecosystems that We Can’t Learn from Studying Populations? -- The Predator-Prey Conundrum -- The Serengeti Ecosystem -- Evolution in the “Ecological Theater” -- Predator-Prey Interactions Tell Only Part of the Story -- Evolution in the “Thermodynamic Theater” -- References -- A Thermodynamic Definition of Ecosystems -- Ecosystems in the 20th Century -- Cycling of Strontium-90 -- Cesium-137 in Food Chains -- Recycling of Isotopes in Norwegian Sheep -- Ecological Energetics -- Is it Time to Bury the Ecosystem Concept? -- A Thermodynamic Definition of Life -- A Thermodynamic Definition of Ecosystems -- The Phase Transition between Order and Chaos -- References -- Thermodynamic Characteristics of Ecosystems -- Equilibrium -- The Equilibrium Law -- Thermodynamic Equilibrium -- Open Thermodynamic Systems -- Ecosystems are Thermodynamically Open Non-Equilibrium Systems -- Work is Performed by Non-equilibrium Systems -- Advantage of a Thermodynamically Open System -- 4.3 Ecosystems are Entropic -- 4.4 Ecosystems are Cybernetic -- Cybernetic Systems -- Economic Systems are Cybernetic Ecosystems are Cybernetic -- The Ecosystem Feedback Function -- Indirect vs. Direct Feedback -- Deviation Dampening and Amplifying Feedback -- Set Points -- Ecosystems are Autocatalytic -- Ecosystems have Boundaries -- Ecosystems are Hierarchical -- Hierarchy in Physical Systems -- Hierarchy in Ecological Systems -- Common Currencies -- Macro-and Micro-System Models -- Why an Ecosystem Model that Includes Everything is not Possible -- A Nested Marine Community -- Ecosystems are Deterministic -- Ecosystems are Information Rich -- An Engineering Definition of Information -- Information to Facilitate Exchange -- High Energy Information -- Low Energy Information -- Information Theory -- Genetic Information -- Ecosystems are Non-Teleological -- Criticisms of Ecosystem Models -- References -- Ecosystem Control: A Top-Down View -- Two Ways to Look at Systems -- Composing and Decomposing Trophic Webs -- Decomposers in Soil Organic Matter -- Decomposers in Marshes and Mangroves -- Control of Systems -- Top-Down vs. Bottom-Up -- Top-Down Exogenous Control -- Exogenous Impacts and Stability -- Top-Down Endogenous Control -- Endogenous Control through Nutrient Recycling -- Autocatalysis -- Control of Microbial Activity -- Inhibition of Microbial Activity by Leaf Sclerophylly -- Inhibition of Microbial Activity Chemical Defenses -- Inhibition of Microbial Activity by Ecological Stoichiometry -- The Synchrony Principle -- The Decay Law -- Direct Nutrient Cycling -- The Role of Animals -- Indirect Interactions -- Marine Systems -- Nutrient and Energy Recycling -- Exogenous Control -- Control in Lakes -- Control in Managed Ecosystems -- References -- Ecosystem Control: A Bottom-Up View -- Species as Arbitrageurs of Energy -- Relation Between Rate of Flow and Mass in Hydraulic Systems -- Relation Between Population Biomass and Rate of Energy Flow -- Equilibrium -- Mechanisms of Adjustment -- Adjustments and Climate Change -- Bird Populations -- Dis-equilibrium -- Population Instability vs. Ecosystem Instability -- Control by Interactions: Direct vs. Indirect -- Indirect Interactions -- Direct Interactions -- Predator – Prey -- Mutualisms -- Competition -- Decomposition -- Parasitism and Disease -- Commensalism and Amensalism -- Persistence of Negative Interactions -- References -- Ecosystem Stability -- Background -- A Thermodynamic Definition -- Regime Shift -- Metastability -- Pulsed Stability -- Resistance and Resilience -- Species Richness and Functional Stability -- Species Richness and Cultural Values -- Keystone Species, and Population and Ecosystem Stability -- 7.5.1 Keystone Species in the Yellowstone region of Wyoming -- References -- 8. Case Studies of Ecosystem Control and Stability -- Walden -- “Harmony in Nature” -- Feedback Produces Nature’s “Harmony” -- Feedback Mechanisms -- Perturbations in Amazon Rain Forests -- Top-Down Control -- The San Carlos Project: A Small-scale, Low Intensity, Short Duration Disturbance -- 8.3.2 The Jarí Project: A Large-scale, High Intensity, Long Duration Disturbance -- Bottom-Up Control -- The El Verde Project -- The Long-Term Ecological Research Project in Puerto Rico -- The Lago Guri Island Project -- The Biological Dynamics of Tropical Rainforest Fragments Project -- What have Case Studies Taught us about Stability of Tropical Ecosystems? -- Tropical Ecosystems are Stable -- Tropical Ecosystems are Unstable -- Energy Flow in Tropical Savannas and Rain Forests -- Insects in Tropical Ecosystems -- Application of Lessons to Other Regions -- Relevance to Temperate Zones -- Relevance to Aquatic Ecosystems -- The Experimental Lakes Project (Ecosystem Control of Species) -- Lake Mendota Studies (Species Control of Ecosystems) -- 8.7 Case Studies as Tests of Thermodynamic Theory -- References -- Entropy and Maximum Power -- Entropy -- 9.2 Entropy in a Steel Bar -- Thermodynamic Equilibrium -- Entropic Gradients -- Capturing and Storing Entropy -- Evapotranspiration and Entropy Reduction -- Life is a Balance between Storing and Releasing Entropy -- The Law of Maximum Entropy Production -- Energy for Metabolism as well as Growth -- Unassisted Entropy Capture is a Unique Characteristic of Life.-9.6Entropy Storage by Ecosystems -- 9.6.1 What Causes Entropy to be Stored? -- 9.7 Capturing Pressure -- 9.8 Entropy and Time -- 9.8.1 Time’s Speed Regulator -- Efficiency of Energy Transformations -- Passage of Time for Cats -- 9.9The Maximum Power Principle.-9.10 Optimum Efficiencies for a Truck and its Driver.-9.11 Sustainability -- References -- A Thermodynamic View of Succession -- 10.1 The Population View -- 10.2 The Thermodynamic View -- 10.2.1 Leaf Area Index and Succession -- 10.2.2 Power Output as a Function of Leaf Area Index -- 10.2.3 What Causes Changes in Leaf Area Index? -- 10.2.4 Maximum Entropy Production Principle -- 10.2.5 Successional Ecosystems Move Further from Thermodynamic Equilibrium -- 10.2.6 Entropy Storage by Animals -- 10.3 The Strategy of Ecosystem Development -- A Problem with Odum’s Strategy -- Why Power Output Continues to Increase -- Revised Definition of Maximum Power -- Costs of Ecosystem Stabilization -- Transactional Costs -- Succession, Power Output, and Efficiency -- 10.5.1 Kleiber’s Law -- Are Ecosystems Spendthrifts? -- Interactions Between Species Facilitate Increase in Power Output -- Facilitation -- Tolerance -- Inhibition -- Intermediate Disturbance Hypothesis -- Nutrient Use Efficiency during Succession -- Succession Following Logging vs Following Agriculture -- 10.10 Thermodynamic View of Succession: Implications for Resource Management -- References -- Panarchy -- The Universal Cycle of Systems -- Panarchy -- Thermodynamic Interpretation of the Sacred Rules -- 11.2.1 Growth and Consolidation -- 11.2.2 Collapse -- Renewal -- Sub-systems -- Panarchy over 2 Billion Years of Evolution -- Consolidation, Bureaucracy and System Collapse -- Bureaucracy in Action (Case Studies) -- Case Study: Panarchy in the Georgia Piedmont -- Thermodynamic Interpretation -- References -- 12. A Thermodynamic View of Evolution -- 12.1 Life – A Physicist's View -- 12.1.1 Life is Produced by Capturing Entropy -- 12.1.2 The Origin of Life -- 12.2 Two Approaches to Evolution -- 12.2.1 The Eco-Evo-Devo View -- 12.2.2 The Thermodynamic View -- 12.2.3 Fitness -- 12.2.4 The “Goal” of Evolution -- 12.3 The Relationship between Species and Environment -- 12.3.1 Evolution’s “Theater” -- 12.3.2 Is Evolution Stochastic or Deterministic? -- 12.4 Ecosystem Evolution -- 12.4.1 Succession was the Clue -- 12.4.2 Ecosystems Moved away from Equilibrium -- 12.4.3 Thermodynamic Mechanisms -- 12.4.4 Biological Mechanisms -- 12.4.5 Ecosystem Fitness -- 12.4.6 Ecosystems Evolve One Step at a Time -- 12.5. The Origin of Ecosystems -- 12.5.1 Origin of Feedback Loops -- 12.5.2 Origin of Trophic Levels -- 12.5.3 Why are there Trophic Levels? -- 12.6 The “Goal” of Ecosystem Evolution -- 12.6.1 Conflicting Goals? -- 12.6.2 “Motivations” of Species -- 12.6.3 The Earth Ecosystem -- 12.6.4 Why is there Resistance to the Idea of Ecosystem Evolution? -- 12.6.5 Evolution of Economic Systems -- 12.7 A Thermodynamic Model of Ecosystem Evolution -- 12.7.1 Network Models -- 12.7.2 Increase in Complexity of Trophic Webs -- 12.7.3 Evolution of Trophic Webs -- 12.7.4 Life Moves Ashore -- 12.8 Biodiversity and the Five Great Extinctions -- 12.8.1 The Cretaceous-Tertiary (K-T) Boundary Extinction -- 12.8.2The Amazing Sustainability of Trophic Chains -- 12.8.3 A Test of Thermodynamic Theory -- 12.9 Panarchy and Evolution -- 12.10 Thermodynamic Requirements for Living Systems on Other Planets -- References -- -- Why is Species Diversity Higher in the Tropics? -- 13.1 Tropical Explorations -- 13.2 A Few Theories -- 13.3 A Thermodynamic Explanation -- 13.3.1 The Latitudinal Energy Gradient -- 13.3.2 The Latitudinal Productivity Gradient -- 13.3.3 The Data -- 13.3.4 Other Factors Affecting Productivity -- 13.4 Empirical Evidence for a High Productivity High Diversity Correlation -- 13.5 Humboldt’s Enigma -- 13.5.1 Are Productivity and Species Richness Correlated on Tropical -- Mountains? -- 13.6 The Mechanism Linking Productivity and Diversity -- 13.7 Answer to “Why is Species Diversity Higher in the Tropics?” -- 13.7.1 Differences within the Tropics -- 13.8 Why is Species Diversity Low at High Latitudes? -- 13.9 An Economic Perspective on D.
    Abstract: Survival of the fittest” is a tautology, because those that are “fit” are the ones that survive, but to survive, a species must be “fit”. Modern evolutionary theory avoids the problem by defining fitness as reproductive success, but the complexity of life that we see today could not have evolved based on selection that favors only reproductive ability. There is nothing inherent in reproductive success alone that could result in higher forms of life. Evolution from a Thermodynamic Perspective presents a non-circular definition of fitness and a thermodynamic definition of evolution. Fitness means maximization of power output, necessary to survive in a competitive world. Evolution is the “storage of entropy”. “Entropy storage” means that solar energy, instead of dissipating as heat in the Earth, is stored in the structure of living organisms and ecosystems. Part one explains this in terms comprehensible to a scientific audience beyond biophysicists and ecosystem modelers. Part two applies thermodynamic theory in non-esoteric language to sustainability of agriculture, and to conservation of endangered species. While natural systems are stabilized by feedback, agricultural systems remain in a mode of perpetual growth, pressured by balance of trade and by a swelling population. The constraints imposed by thermodynamic laws are being increasingly felt as economic expansion destabilizes resource systems on which expansion depends.
    Type of Medium: Online Resource
    Pages: XXVI, 384 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030851866
    URL: https://doi.org/10.1007/978-3-030-85186-6
    DOI: 10.1007/978-3-030-85186-6
    DDC: 577
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    Guanacos and People in Patagonia : A Social-Ecological Approach to a Relationship of Conflicts and Opportunities (2022)
    Cham :Springer International Publishing :
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    Keywords: Ecology . ; Conservation biology. ; Applied ecology. ; Environmental management. ; Ecology. ; Conservation Biology. ; Applied Ecology. ; Environmental Management.
    Description / Table of Contents: Introduction: Taxonomy, distribution and conservation status of wild guanaco’s populations -- 1. Zooarchaeological and socio-anthropological perspective of the human - guanaco (Lama guanicoe) interaction over the last 6000 years in the Patagonia, Argentina -- 2. Interspecific competition between guanacos and livestock and its impact on Patagonian rangelands: review and synthesis -- 3. Health status of Patagonian guanaco and its relevance for conservation -- 4. Patagonian pumas and their ungulate prey in the 21st century, a key interaction in a degraded environment -- 5. International policies and national legislation concerning guanaco conservation, management and trade in Argentina -- 6. Guanaco sustainable management as a conservation strategy and socioeconomic rural development -- 7. Historical perspective and current advances in ecology, conservation and management of the guanaco in the Chilean Patagonia -- 8. Lessons for the future of conservation and sustainable use of guanacos.
    Abstract: This book relates one of the most representative species of Patagonian wildlife, the guanaco, to human societies across time, and explores how that relationship has changed over time due to different land uses and productive interests. The book provides information to understand these interactions, and contextualizes the current situation of this species. In some cases, it proposes possible solutions to conflicts, and also shows ongoing activities aimed at sustainable use and conservation. The audience for this book includes researchers, graduate students, policy makers and conservation and rural development professionals. In addition, it will serve as a tool for application authorities and field technicians on the use and conservation of wildlife, to define management actions for this species. .
    Type of Medium: Online Resource
    Pages: XII, 241 p. 23 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031066566
    Series Statement: Natural and Social Sciences of Patagonia,
    URL: https://doi.org/10.1007/978-3-031-06656-6
    DOI: 10.1007/978-3-031-06656-6
    DDC: 577
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    Enhancing Environmental Education Through Nature-Based Solutions (2022)
    Cham :Springer International Publishing :
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    Keywords: Ecology . ; Environment. ; Science Study and teaching. ; Environmental health. ; Sustainability. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Ecology. ; Environmental Sciences. ; Science Education. ; Environmental Health. ; Sustainability. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Part I: About Environmental Education -- Chapter 1 - Training and dissemination about the Environment: keys to impulse the abiotic component of Environmental Education -- Chapter 2 Educating to deliver environmentally focused social innovation -- Chapter 3 - Environmental education for sustainable development: working for fundamental rights -- Chapter 4 - Nature as a teaching resource and the nature of learning -- Part II: Environmental Education and it´s Teaching -- Chapter 5 - The importance of Nature-based solutions to enhance Cabo Verde's Environment -- Chapter 6- Development of Scientific Literacy and the impact of environmental attitudes of citizens in a geological natural space -- Chapter 7- A PBL approach to Environmental Education through a Field Trip and a Science Centre Visit -- Chapter 8- Living labs in higher education: sustainable buildings technologies -- Chapter 9 - What is doing Latin America regarding the teaching of Nature-based solutions to boost Environmental Education? -- Chapter 10 - Lessons learned from including aquaponic experiments into five different tertiary education curricula -- Chapter 11 - Recommendations for promoting Environmental Education through Nature-based solutions at Turkish Higher Education Institutes -- Part III: Environmental Education and Social Engagement -- Chapter 12 - Bees and Society: native biodiversity as a strategy for environmental education based on the processes of nature -- Chapter 13- Perceptions about Sustainable Development of visitants in an Environmental Education Natural Park -- Chapter 14 - Start Park project: co-designing green-blue infrastructures to build resilient communities to climate change -- Chapter 15 - Societal embedding in geoparks: a case study in Portugal -- Chapter 16 - Environmental Education in Naturtejo UNESCO Global Geopark (Portugal): a nature-based approach -- Part IV: – Environmental Education and Nature-Based Solutions -- Chapter 17- Green Roof and walls technology standardisation and market across Europe -- Chapter 18- How Nature-Based Solutions can Contribute to Enhance Circularity in Cities -- Chapter 19- Nature-based solutions to promote environmental education on integral ecological sanitation -- Chapter 20 - Nature-based solutions for environmental education in the East Asian context -- Chapter 21- Decarbonizing the European energy sector: frameworks, examples and how education plays a key role -- Chapter 22- Nature-based solutions for water pollution control: promoting environmental education through case studies.
    Abstract: This Book presents innovative and state of the art studies developed in Environmental Education in different countries to highlight this theme and promote its implementation all over the world. It will give a scientific perspective of Nature-based solutions to promote environmental education in all citizens and a more educational perspective as to how this approach can be implemented at schools and universities. Not less important is that includes science communication as a key factor for training and disseminating about the environment. The invited authors are recognized experts with excellent work developed in Environmental Education. This contributed volume presents innovative and creative work in the area giving a step forward in the implementation of Environmental Education, namely as a target of 2020 United Nations Agenda for Sustainable Development. The invitation of authors from many different countries allows the creation of a network and subsequently the book will bring concrete ideas as to how to develop operational capacities to bring added values to Environmental Education at an international level.
    Type of Medium: Online Resource
    Pages: XI, 432 p. 117 illus., 89 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030918439
    Series Statement: Integrated Science, 4
    URL: https://doi.org/10.1007/978-3-030-91843-9
    DOI: 10.1007/978-3-030-91843-9
    DDC: 577
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    Cancer Biomarkers in Diagnosis and Therapeutics (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Tumor markers. ; Cancer. ; Cancer Treatment. ; Nanomedicine. ; Tumour Biomarkers. ; Cancer Biology. ; Cancer Therapy. ; Cancer Nanotechnology.
    Description / Table of Contents: Chapter 1. Introduction to cancer biomarkers -- Chapter 2.Technologies for identification and validation of cancer biomarkers -- Chapter 3. BIOMARKERS FOR CANCER DRUG DEVELOPMENT -- Chapter 4. Clinical proteomics: diagnostics and prognostic markers of Cancer -- Chapter 5.Microbiome as cancer biomarkers -- Chapter 6. Predictive biomarkers for anticancer drugs -- Chapter 7. Biomarkers in Cancer Survival and Drug Resistance -- Chapter 8. Biomarkers in tumor recurrence and metastasis -- Chapter 9. Biomarkers for Cancer Immunotherapy -- Chapter 10. Role of Biomarkers in Personalized Medicine -- Chapter 11.Development of Novel Cancer Biomarkers for Diagnosis and Prognosis -- Chapter 12. Nanotechnology for Cancer Biomarkers.
    Abstract: This book illustrates the basics and underlying molecular machinery of cancer cells and biochemical assays that detect the type and stage of cancer through cell signaling biomarkers. It starts with a brief introduction to cancer biomarkers and addresses technologies for identifying and validating cancer biomarkers, biomarkers for cancer drug development, prognostic and diagnostic biomarkers, and microbiome as cancer biomarkers. It reviews predictive biomarkers for anticancer drugs, biomarkers in cancer survival and drug resistance, biomarkers in tumor recurrence and metastasis, the role of the biomarker in immunotherapy and personalized medicine, and the development of a novel cancer biomarker. Finally, this book also underpins the role of nanotechnology in the use and detection of cancer biomarkers for enhanced sensitivity and specificity. Lastly, it discusses the challenges with biomarkers in cancer drug discovery and development. This volume is an indispensable tool for researchers working in the field of cancer and also for clinical oncologists.
    Type of Medium: Online Resource
    Pages: XII, 365 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811657597
    URL: https://doi.org/10.1007/978-981-16-5759-7
    DOI: 10.1007/978-981-16-5759-7
    DDC: 571.978
    Language: English
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    Microfluidics and Biosensors in Cancer Research : Applications in Cancer Modeling and Theranostics (2022)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Biochemical markers. ; Microfluidics. ; Pharmacology. ; Cancer Treatment. ; Cancer Biology. ; Biomarkers. ; Microfluidics. ; Pharmacology. ; Cancer Therapy.
    Description / Table of Contents: Part 1. Fundamentals of Microfluidics and Biosensors -- Chapter 1. Fundamentals of Biosensors and Detection Methods -- Chapter 2. How to Get Away with Gradients -- Chapter 3. Sensors and Biosensors in Organs-on-a-chip Platforms -- Chapter 4. Current Trends in Microfluidics and Biosensors for Cancer Research Applications -- Part 2. Modelling the Tumor Microenvironment and Its Dynamic Events -- Chapter 5. The Tumor Microenvironment — an Introduction for the Development of Microfluidic Devices -- Chapter 6. Biomaterials for Mimicking and Modelling Tumor Micro-environment -- Chapter 7. Advancing Tumor Microenvironment Research by Combining Organs-on-chips and Biosensors -- Chapter 8. Microfluidic-driven Biofabrication and the Engineering of Cancer-like Microenvironments -- Chapter 9. Advances in 3d Vascularized Tumor-on-a-chip Technology -- Part 3. Cancer Detection and Diagnosis -- Chapter 10. Biosensors Advances: Contributions to Cancer Diagnostics and Treatment -- Chapter 11. Flexible Sensing Systems for Cancer Diagnostics -- Chapter 12. Coupling Micro-physiological Systems and Biosensors for Improving Cancer Biomarkers Detection -- Chapter 13. Microfluidic Biosensor-based Devices for Rapid Diagnosis and Effective Anti-cancer Therapeutic Monitoring for Breast Cancer Metastasis -- Chapter 14. Liquid Biopsies: Flowing Biomarkers -- Chapter 15. From Exosomes to Circulating Tumor Cells: Using Microfludics to Detect High Predictive Cancer Biomarkers -- Chapter 16. Microfluidics for the Isolation and Detection of Circulating Tumor Cells -- Chapter 17. Evolution in Automatized Detection of Cancer Cells: Advances in Magnetic Microcytometers -- Chapter 18. Droplet-based Microfluidic Chip Design, Fabrication and Use for Ultrahigh-throughput DNA Analysis and Quantification -- Chapter 19. Emerging Microfluidic and Biosensor Technologies for Improved Cancer Theranostics -- Part 4. Clinical Applications: Towards Personalized Medicine -- Chapter 20. Microfluidics for Cancer Biomarker Discovery, Research and Clinical Application -- Chapter 21. Methods for the Detection of Circulating Biomarkers in Cancer Patients -- Chapter 22. Advances in Microfluidics for the Implementation of Liquid Biopsy in Clinical Routine.
    Abstract: This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics. Over the last decades, considerable effort has been made to develop new technologies to improve the diagnosis and treatment of cancer. Microfluidics has proven to be a powerful tool for manipulating biological fluids with high precision and efficiency and has already been adopted by the pharmaceutical and biotechnology industries. With recent technological advances, particularly biosensors, microfluidic devices have increased their usefulness and importance in oncology and cancer research. The aim of this book is to bring together in a single volume all the knowledge and expertise required for the development and application of microfluidic systems and biosensors in cancer modeling and theranostics. It begins with a detailed introduction to the fundamental aspects of tumor biology, cancer biomarkers, biosensors and microfluidics. With this knowledge in mind, the following sections highlight important advances in developing and applying biosensors and microfluidic devices in cancer research at universities and in the industry. Strategies for identifying and evaluating potent disease biomarkers and developing biosensors and microfluidic devices for their detection are discussed in detail. Finally, the transfer of these technologies into the clinical environment for the diagnosis and treatment of cancer patients will be highlighted. By combining the recent advances made in the development and application of microfluidics and biosensors in cancer research in academia and clinics, this book will be useful literature for readers from a variety of backgrounds. It offers new visions of how this technology can influence daily life in hospitals and companies, improving research methodologies and the prognosis of cancer patients.
    Type of Medium: Online Resource
    Pages: XIX, 590 p. 100 illus., 99 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031040399
    Series Statement: Advances in Experimental Medicine and Biology, 1379
    URL: https://doi.org/10.1007/978-3-031-04039-9
    DOI: 10.1007/978-3-031-04039-9
    DDC: 571.978
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    Lateral Asymmetry in Animals : Predator-Prey Interactions, Dynamics, and Evolution (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Ecology . ; Anatomy. ; Biomathematics. ; Behavior genetics. ; Evolution (Biology). ; Ecology. ; Anatomy. ; Mathematical and Computational Biology. ; Behavioral Genetics. ; Ecology. ; Evolutionary Biology.
    Description / Table of Contents: Chapter 1. Laterality of Fish – Anti-symmetry in Fish Populations Maintained by the Interspecific Interaction -- Chapter 2. Universality of laterality among fish and invertebrates in aquatic communities -- Chapter 3.Predominance of Cross Predation or Parallel Predation in Fish -- Chapter 4.Behavioral laterality in the scale-eating cichlid fish: detailed movement, development, and neuronal mechanisms -- Chapter 5.Models of Lateral Asymmetry Dynamics:Realistic Oscillations by Time Delay andFrequency Dependence -- Chapter 6.Mathematical models of predators and prey with laterality -- Chapter 7.Statistical Analysis of Lateral Asymmetry:Detect Antisymmetry and Oscillation fromUnequal-Interval Binomial Data -- Chapter 8.Models of Genetic System of LateralAsymmetry: Population Dynamics DriveEvolution of Genetic System -- Chapter 9.Mechanisms Underlying Variations in the Dentition Asymmetry of Asian Snail-Eating Snakes -- Chapter 10.Single-gene speciation, balanced polymorphism, and antagonistic coevolution in left-right asymmetry of land snails.
    Abstract: This book presents the latest research findings on the laterality of fish and other animals. It describes all aspects of lateral asymmetry, including ecology, morphology, behaviour, dynamics of lefty and righty morphs, genetics and evolution, through field observations, experiments and modeling. Lateral asymmetry in scale-eating cichlids gives a simple and beautiful example of negative frequency-dependent selection and resulting oscillation of lefty and righty morph frequencies. Lateral dimorphism is found not only in scale-eaters but in all orders of fish, shrimps and cuttlefish. Lateral asymmetry interacts between species through "cross-predation." Contrary to fish, lateral asymmetry in snails acts as, in most cases, positive frequency-dependent selection and provides deep insights into speciation. Especially, snakes eating righty snails facilitate speciation of lefty snails. As a collaboration work of field ecologists and theoretical biologists, this book covers a variety of topics on lateral asymmetry, which are consistently related to predation. The topics include behavioral ecology, population dynamics, physiology, evolution, genetics, development, learning and neuroscience, statistics, with the subjects of fish, shrimp, prawn, and crayfish, crab, cuttlefish, and snake and snail. Chapters cover new research results such as cuttlefish laterality dynamics, interaction between laterality of snails and snakes, evolution of laterality genetic system, and statistical analysis of laterality oscillation. Readers will appreciate the simplicity and beauty of lateral asymmetry and its profound impact on ecology and evolution.
    Type of Medium: Online Resource
    Pages: XII, 295 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913426
    Series Statement: Ecological Research Monographs,
    URL: https://doi.org/10.1007/978-981-19-1342-6
    DOI: 10.1007/978-981-19-1342-6
    DDC: 577
    Language: English
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    Greenhouse Gases: Sources, Sinks and Mitigation (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Environmental chemistry. ; Urban ecology (Biology). ; Ecology. ; Environmental Chemistry. ; Urban Ecology.
    Description / Table of Contents: Chapter 1. Introduction to Green House Gases: Sources, Sinks and Mitigation -- Chapter 2. Source Apportionment of Greenhouse Gases in the Atmosphere -- Chapter 3. IDENTIFICATION OF MAJOR SINKS OF GREENHOUSE GASES -- Chapter 4. Greenhouse Gas Emission Flux from Forest Ecosystem -- Chapter 5. EFFECT OF GREEN HOUSE GASES ON HUMAN HEALTH -- Chapter 6. Air Pollution and Greenhouse Gases Emissions: Implications in Food Production and Food Security -- Chapter 7. Optimization of Greenhouse Gas Emissions through Simulation Modeling: Analysis and Interpretation -- Chapter 8. ROLE OF BIOMASS BURNING IN GREENHOUSE GASES EMISSION -- Chapter 9. Ozone Impacts and Climate Forcing: Thailand as a Case Study -- Chapter 10. Role of Nanotechnology in Combating CO2 in Atmosphere -- Chapter 11. Mitigation Strategies of Greenhouse Gas Control: Policy Measures.
    Abstract: This book begins with a brief background on greenhouse gases sources and sinks and continues with a discussion in different sectors including forest fluxes to human health and modeling techniques to policy measures. The chapters explore in detail about the GHG emission budgets, mitigation strategies, technical advancement and input-output analysis. Greenhouse gases (GHGs) occur naturally in our atmosphere and are essential to the survival of most of the organisms on the planet earth. GHGs such as such as carbon dioxide, methane, nitrous oxide, and ozone etc. play a major role in balancing the radiative budget, by absorbing or emitting some of the infrared rays reflecting from the earth’s surface. But unfortunately, anthropogenic activities like use of fossil fuel, intensive agriculture and livestock farming, use of synthetic fertilizers, deforestation, and industrial processes etc. have drastically interfered in the natural air composition, by releasing excess greenhouse gases into the atmosphere. This has led to the increase in the ability of the atmosphere to absorb more infrared energy. This book is a complete information set covering all aspects of GHGs, sources, sinks and control/mitigation strategies. This book is also written in simple language with helpful photographs, diagrams and flowcharts which will make the reader comfortable in understanding the concepts a more relatively easier way. The book is a valuable tool for students in Environmental Science, Ecology, Biological Science, Economics and Agriculture. It is unique to environmental consultants, researchers and other professionals involved in climate change studies, Non-governmental organizations (NGO’s).
    Type of Medium: Online Resource
    Pages: XVI, 257 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811644825
    URL: https://doi.org/10.1007/978-981-16-4482-5
    DOI: 10.1007/978-981-16-4482-5
    DDC: 577
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    Cancer Diagnostics and Therapeutics : Current Trends, Challenges, and Future Perspectives (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Tumors Blood-vessels. ; Blood-vessels Growth. ; Cancer Imaging. ; Cancer Genetic aspects. ; Cancer Biology. ; Tumour Angiogenesis. ; Cancer Imaging. ; Cancer Genetics and Genomics.
    Description / Table of Contents: Part I: Basic Background -- Chapter 1. Fighting with Cancer: A Common Man’s Dilemma -- Chapter 2. Introduction to Cell Biology and Cell Behavior in Cancer -- Chapter 3. Tumor Biology: An Introduction -- Chapter 4. Role of Angiogenesis in Tumours -- Chapter 5. Biology, Chemistry and Physics of Cancer Cell Motility and Metastasis -- Part II: Diagnostics and Theory -- Chapter 6. MRI, CT and PETSCAN: Engineer’s Perspective -- Chapter 7. Diffusion, MRI and Cancer Diagnosis: Physicist’s Outlook -- Chapter 8. Oncology: Radiation Oncologist’s View -- Chapter 9. Oncology: Biochemists’ Perspective -- Chapter 10. Oncology: Pathologist’s View -- Part III: Cancer Therapeutics -- Chapter 11. Surgical Oncology: An Overview -- Chapter 12. Medical Oncology in Cancer Treatment -- Chapter 13. Chemotherapy Effects on Immune System -- Chapter 14. Telomerase and its therapeutic implications in Cancer -- Chapter 15. Pain Management in Oncology -- Part IV: Emerging Trends in Cancer Research -- Chapter 16. New Approaches in Cancer Research: Stem-cell research, Translational Research, Immuno-therapy, and others -- Chapter 17. Cancer Cell Lines: Its Implication for Therapeutic Use -- Chapter 18. Genomics of Cancer -- Chapter 19. Chapter 19: Diabetes and Cancer -- Chapter 20. Oncology Informatics, AI, and Drug Discovery -- Chapter 21. Radiomics: Cropping More from the Images -- Part V: Epidemiology and Statistics of Cancer -- Chapter 22. Statistics in Cancer: Diagnosis, Disease Progression, Treatment Efficacy and Patient Survival Studies -- Chapter 23. Epidemiology of Cancer: Asian Perspective -- Chapter 24. Cancer Genomics and Diagnostics: Northeast Indian Scenario.
    Abstract: This book presents multiple facets of cancer biology, including cancer diagnosis, therapeutics to the latest developments in cancer informatics, and applications of artificial intelligence for improving oncologic care. The initial section of the book discusses factors contributing to the development and causes of cancer. The subsequent sections discuss the basic principle of imaging and therapeutic techniques, including MRI, CT, and positron emission tomography (PET) Scan. The book further, explores the implications of cancer chemotherapy on the immune system and emphasizes the effective management of cancer-related pain. Towards the end, it covers recent advancements in cancer treatment, including targeted therapy, immunotherapy, interventional radiotherapy, and stem cell-based therapy. Lastly, it summarizes essential strategic elements of cancer informatics for improving patient outcome.
    Type of Medium: Online Resource
    Pages: XIX, 529 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647529
    URL: https://doi.org/10.1007/978-981-16-4752-9
    DOI: 10.1007/978-981-16-4752-9
    DDC: 571.978
    Language: English
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    Lipid Metabolism in Tumor Immunity (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Bioinformatics. ; Immunology. ; Cancer Biology. ; Computational and Systems Biology. ; Immunology.
    Description / Table of Contents: 1. Introduction: Introduction of lipids, lipid metabolism and tumor immunity -- 2. ipid metabolism and lipidomics -- 3. Applications of lipidomics in tumour immunity.-4. Overview: Lipid metabolism in tumour microenvironment -- 5. Lipid metabolism in cancer cells -- 6. Lipid metabolism in tumour-associated NK -- 7. Lipid metabolism in tumour-associated macrophages -- 8. Lipid metabolism in tumour-associated MDSCs -- 9. Lipid metabolism in tumour-associated fibroblasts -- 10. Lipid metabolism in tumour-associated B cells -- 11. Lipid metabolism in tumour-infiltrating T cells -- 12. Lipid metabolism and angiogenesis -- 13. Lipid metabolism and tumor antigen-presenting -- 14. Lipid metabolism and immune checkpoints.
    Abstract: This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery. .
    Type of Medium: Online Resource
    Pages: XI, 211 p. 24 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813367852
    Series Statement: Advances in Experimental Medicine and Biology, 1316
    URL: https://doi.org/10.1007/978-981-33-6785-2
    DOI: 10.1007/978-981-33-6785-2
    DDC: 571.978
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    Tumor Microenvironment : Signaling Pathways – Part B (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Biophysics. ; Cell interaction. ; Cytology. ; Cancer Microenvironment. ; Mechanobiological Cell Signaling. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 191 p. 31 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030471897
    Series Statement: Advances in Experimental Medicine and Biology, 1270
    URL: https://doi.org/10.1007/978-3-030-47189-7
    DOI: 10.1007/978-3-030-47189-7
    DDC: 571.978
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    Online Resource
    Cancer Biology: How Science Works (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Genetics. ; Molecular biology. ; Cancer Biology. ; Genetics and Genomics. ; Molecular Biology.
    Description / Table of Contents: 1. Introduction to cancer -- 2. Oncogenes, signal transduction and the hallmarks of cancer -- 3. Tumor suppressor genes and cell fate control -- 4. Multi-step tumorigenesis and genome instability -- 5. Cancer genomics -- 6. Cancer epigenomics -- 7. Aging and cancer -- 8. Tumor microenvironment -- 9. Metastasis and cachexia -- 10. Cancer immunity -- 11. Architecture of cancer therapies.
    Abstract: Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
    Type of Medium: Online Resource
    Pages: XVII, 167 p. 72 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030756994
    URL: https://doi.org/10.1007/978-3-030-75699-4
    DOI: 10.1007/978-3-030-75699-4
    DDC: 571.978
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    Obesity and Cancer (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Diseases. ; Immunology. ; Bioinformatics. ; Cancer Biology. ; Diseases. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Obesity induced chronic low-level inflammation and cancers -- Chapter 2. Adipose tissue produced estrogen as risk factor for cancers -- Chapter 3. Insulin and Insulin-like growth factor-1 associated cancers.-Chapter 4. Adipokines play important role in cell proliferation and antiproliferation -- Chapter 5. mTOR and AMP-activated protein kinase in obesity and cancer -- Chapter 6. Immune response and oxidative stress in obesity induced cancer -- Chapter 7. Role of gene polymorphism in obesity and cancer -- Chapter 8. Therapeutic role of green tea in obesity and cancer -- Chapter 9. Effect of dietary phytochemicals in obesity and cancer -- Chapter 10. Resveratrol as anti-obesity and anticancer agent -- Chapter 11. EGCG as anti-obesity and anticancer agent -- Chapter 12. miRNAs as therapeutic target in obesity and cancer -- Chapter 13. In silico updates on lead identification for obesity and cancer -- Chapter 14. In vivo models for obesity and obesity related carcinogenesis -- Chapter 15. Estrogen signaling based current and potential therapies against obesity and related diseases -- Chapter 16. Autophagy at the crossroad of obesity mediated cancer progression.
    Abstract: This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry. .
    Type of Medium: Online Resource
    Pages: IX, 361 p. 38 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618468
    URL: https://doi.org/10.1007/978-981-16-1846-8
    DOI: 10.1007/978-981-16-1846-8
    DDC: 571.978
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    Alpine Plant Life : Functional Plant Ecology of High Mountain Ecosystems (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Botany. ; Physical geography. ; Conservation biology. ; Ecology. ; Plant Science. ; Earth System Sciences. ; Conservation Biology.
    Description / Table of Contents: PRELIMINARY (ToC of second edition) 1 Plant ecology at high elevations -- The concept of limitation -- A regional and historical account -- The challenge of alpine plant research -- 2 The alpine life zone -- Altitudinal boundaries -- Global alpine land area -- Alpine plant diversity -- Origin of alpine floras -- Alpine growth forms -- 3 Alpine climate -- Which alpine climate -- Common features of alpine climates -- Regional features of alpine climates -- 4 The climate plants experience -- Interactions of relief, wind and sun -- How alpine plants influence their climate -- The geographic variation of alpine climate -- 5 Life under snow: protection and limitation -- Temperatures under snow -- Solar radiation under snow -- Gas concentrations under snow -- Plant responses to snowpack -- 6 Alpine soils -- Physics of alpine soil formation -- The organic compound -- The interaction of organic and inorganic compounds -- 7 Alpine treelines -- About trees and lines -- Current altitudinal positions of climatic treelines -- Treeline-climate relationships -- Intrazonal variations and pantropical plateauing of alpine treelines -- Treelines in the past -- Attempts at a functional explanation of treelines -- A hypothesis for treeline formation -- Growth trends near treelines -- Evidence for sink limitation -- 8 Climatic stress -- Survival of low temperature extremes -- Avoidance and tolerance of low temperature extremes -- Heat stress in alpine plants -- Ultraviolet radiation — a stress factor -- 9 Water relations -- Ecosystem water balance -- Soil moisture at high altitudes -- Plant water relations — a brief review of principles -- Water relations of alpine plants -- Desiccation stress -- Water relations of special plant types -- 10 Mineral nutrition -- Soil nutrients -- The nutrient status of alpine plants -- Nutrient cycling and nutrient budgets -- Nitrogen fixation -- Mycorrhiza -- Responses of vegetation to variable nutrient supply -- 11 Uptake and loss of carbon -- Photosynthetic capacity of alpine plants -- Photosynthetic responses to the environment -- Daily carbon gain of leaves -- The seasonal carbon gain of leaves -- C4 and CAM photosynthesis at high altitudes -- Tissue respiration of alpine plants -- Ecosystem carbon balance -- 12 Carbon investments -- Non-structural carbohydrates -- Lipids and energy content -- Carbon costs of leaves and roots -- Whole plant carbon allocation -- 13 Growth dynamics and phenology -- Seasonal growth -- Diurnal leaf extension -- Rates of plant dry matter accumulation -- Functional duration of leaves and roots -- 14 Cell division and tissue formation -- Cell size and plant size -- Mitosis and the cell cycle -- From meristem activity to growth control -- 15 Plant biomass production -- The structure of alpine plant canopies -- Primary productivity of alpine vegetation -- Plant dry matter pools -- Biomass losses through herbivores -- 16 Plant reproduction -- Flowering and pollination -- Seed development and seed size -- Germination -- Alpine seed banks and natural recruitment -- Clonal propagation -- Alpine plant age -- Community processes -- 17 Global change at high elevation -- Alpine land use -- The impact of altered atmospheric chemistry -- Climatic change and alpine ecosystems -- References (with chapter annotation) -- Taxonomic index (genera) -- Geographical index -- Color plates -- Plant life forms -- The alpine life zone -- Environmental stress -- The human dimension.
    Abstract: This book is a completely revised, substantially extended treatment of the physical and biological factors that drive life in high mountains. The book covers the characteristics of alpine plant life, alpine climate and soils, life under snow, stress tolerance, treeline ecology, plant water, carbon, and nutrient relations, plant growth and productivity, developmental processes, and two largely novel chapters on alpine plant reproduction and global change biology. The book explains why the topography driven exposure of plants to dramatic micro-climatic gradients over very short distances causes alpine biodiversity to be particularly robust against climatic change. Geographically, this book draws on examples from all parts of the world, including the tropics. This book is complemented with novel evidence and insight that emerged over the last 17 years of alpine plant research. The number of figures – mostly in color – nearly doubled, with many photographs providing a vivid impression of alpine plant life worldwide. Christian Körner was born in 1949 in Austria, received his academic education at the University of Innsbruck, and was full professor of Botany at the University of Basel from 1989 to 2014. As emeritus Professor he is continuing alpine plant research in the Swiss Alps.
    Type of Medium: Online Resource
    Pages: XIX, 500 p. 319 illus., 283 illus. in color. , online resource.
    Edition: 3rd ed. 2021.
    ISBN: 9783030595388
    URL: https://doi.org/10.1007/978-3-030-59538-8
    DOI: 10.1007/978-3-030-59538-8
    DDC: 577
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    Research Methods of Environmental Physiology in Aquatic Sciences (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Ecology . ; Water. ; Hydrology. ; Environmental chemistry. ; Environmental sciences. ; Physics. ; Environment. ; Ecology. ; Water. ; Environmental Chemistry. ; Environmental Physics. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1 Measurement of environmental parameters affecting marine plankton physiology -- Chapter 2 Plankton culture techniques -- Chapter 3 Determination of Key Enzymes involved in primary productivity -- Chapter 4 Analyses of pigments -- Chapter 5 Measurements and analyses of photosynthesis and respiration -- Chapter 6 Chlorophyll fluorescence techniques and applications -- Chapter 7 Biochemical and molecular methods -- Chapter 8 Research methods for animal and virus.
    Abstract: This book presents methods for investigating the effects of aquatic environmental changes on organisms and the mechanisms involved. It focuses mainly on photosynthetic organisms, but also provides methods for virus, zooplankton and other animal studies. Also including a comprehensive overview of the current methods in the fields of aquatic physiology, ecology, biochemistry and molecular approaches, including the advantages and disadvantages of each method, the book is a valuable guide for young researchers in marine or aquatic sciences studying the physiological processes associated with chemical and physical environmental changes.
    Type of Medium: Online Resource
    Pages: XI, 352 p. 83 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811553547
    URL: https://doi.org/10.1007/978-981-15-5354-7
    DOI: 10.1007/978-981-15-5354-7
    DDC: 577
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    The Atlantic Forest : History, Biodiversity, Threats and Opportunities of the Mega-diverse Forest (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Botany. ; Zoology. ; Conservation biology. ; Ecology. ; Plant Science. ; Zoology. ; Conservation Biology.
    Description / Table of Contents: Part 1: Historical and biogeographical aspects -- The Atlantic Forest: an introduction to the megadiverse forest of Southern America -- The Atlantic Forest Ecological History: from pre-history to the Anthropocene -- The North-eastern Atlantic Forest: biogeographical, historical and current aspects in the Sugarcane Zone -- The Hileia Baiana - an assessment of natural and historical aspects of the land use and degradation of the central corridor of the Brazilian Atlantic Forest -- The southern Atlantic Forest: Use, degradation, and perspectives for conservation -- Part II – Biodiversity -- Tree diversity in the Brazilian Atlantic Forest: biases and general patterns using different sources of information -- Vascular Epiphytes of the Atlantic Forest: diversity and community ecology -- Social Insects of the Atlantic Forest -- Tetrapod diversity in the Atlantic Forest: maps and gaps -- Freshwater Studies in Atlantic Forest: general overview and prospects -- Part III – Threats -- Land-cover changes and an uncertain future: will the Brazilian Atlantic Forest lose the chance to become a hopespot? -- Climate change and biodiversity in the Atlantic Forest: best climatic models, predicted changes and impacts, and adaptation options -- Non-native species introductions, invasions, and biotic homogenization in the Atlantic Forest -- Causes and consequences of large-scale defaunation in the Atlantic forest -- Pollination systems in the Atlantic Forest: characterization, threats, and opportunities -- IV - Opportunities -- Atlantic Forest: ecosystem services linking people and biodiversity -- Changing the agriculture paradigm in the Brazilian Atlantic Forest: the importance of agroforestry -- Engaging people for large-scale forest restoration: Governance lessons from the Atlantic Forest of Brazil -- The Atlantic Forest Trail: connecting people, biodiversity and protected areas -- Conservation initiatives in the Brazilian Atlantic forest -- Financing conservation in the Brazilian Atlantic Forest -- Integrating researchers for understanding the biodiversity in Atlantic Forest -- The future of the Atlantic Forest.
    Abstract: The Atlantic Forest is one of the 36 hotspots for biodiversity conservation worldwide. It is a unique, large biome (more than 3000 km in latitude; 2500 in longitude), marked by high biodiversity, high degree of endemic species and, at the same time, extremely threatened. Approximately 70% of the Brazilian population lives in the area of this biome, which makes the conflict between biodiversity conservation and the sustainability of the human population a relevant issue. This book aims to cover: 1) the historical characterization and geographic variation of the biome; 2) the distribution of the diversity of some relevant taxa; 3) the main threats to biodiversity, and 4) possible opportunities to ensure the biodiversity conservation, and the economic and social sustainability. Also, it is hoped that this book can be useful for those involved in the development of public policies aimed at the conservation of this important global biome.
    Type of Medium: Online Resource
    Pages: XXX, 517 p. 66 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030553227
    URL: https://doi.org/10.1007/978-3-030-55322-7
    DOI: 10.1007/978-3-030-55322-7
    DDC: 577
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    Skin Cancer: Pathogenesis and Diagnosis (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Biomedical engineering. ; Biochemical markers. ; Nanomedicine. ; Cancers. ; Biomedical Engineering and Bioengineering. ; Biomarkers. ; Cancer Nanotechnology.
    Description / Table of Contents: Chapter 1. Cancer of the Skin:Type and Etiology -- Chapter 2. Therapeutic intervention in skin cancer: Future prospects -- Chapter 3. Melanin Based Classification of Skin Types and Their Susceptibility to UV-induced Cancer -- Chapter 4. The Epidemiology of Skin Cancer Worldwide -- Chapter 5. UV-R induced Vitamin D synthesis and skin cancer -- Chapter 6. The role of microbiome in the induction, diagnosis and therapy of skin cancer -- Chapter 7. Skin Cancer: Molecular Biomarker for Diagnosis, Prognosis, Prevention and Targeted Therapy -- Chapter 8. Therapeutics intervention of skin cancer in the OMICS era -- Chapter 9. Artificial intelligence in Skin Cancer: Diagnosis and Therapy -- Chapter 10. Biomedical engineering in cancer diagnosis and therapy -- Chapter 11. Skin cancer treatment with Emphasis on Nanotechnology -- Chapter 12. Non-long coding RNA and role in skin cancer diagnosis and therapy -- Chapter 13. Potential of long non-coding RNAs in the diagnosis and therapy of melanoma skin cancer.-.
    Abstract: This book highlights the molecular and cellular mechanisms involved in the initiation and progression of skin cancer. It also explains the role of the environment in skin cancer development and explores the potential of microbiome in the diagnosis, prevention and treatment of skin cancer. The book also presents potential biomarkers for early detection of skin cancer and discusses recent advances in skin cancer prevention and treatment using photodynamic therapy. Lastly, it summarizes the applications of biomedical engineering, non-coding and nanotechnology in the diagnosis and therapeutics in skin cancer. It is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, and dermatologists.
    Type of Medium: Online Resource
    Pages: VIII, 250 p. 27 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811603648
    URL: https://doi.org/10.1007/978-981-16-0364-8
    DOI: 10.1007/978-981-16-0364-8
    DDC: 571.978
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    Genetic Polymorphism and cancer susceptibility (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Genetics. ; Medical genetics. ; Cancers. ; Genetics and Genomics. ; Medical Genetics. ; Cancer Biology.
    Description / Table of Contents: Chapter 1. Polymorphisms and Mutation: What is difference? -- Chapter 2. Single nucleotide polymorphisms and pharmacogenomics -- Chapter 3. Impact of MicroRNA Polymorphisms on Breast Cancer Susceptibility -- Chapter 4. From inflammation to cancer: Role of genetic polymorphisms of Inflammatory Pathway Molecules in Gastric Cancer -- Chapter 5. Colorectal Cancer and genetic polymorphism in key regulatory low penetrance genes -- Chapter 6. Role of Genetic Polymorphisms in Breast Cancer -- Chapter 7. Genetic Polymorphisms of Essential Immune Pathogenic Response Genes and Risk of Cervical Cancer -- Chapter 8. Thyroid Cancer and genetic polymorphism -- Chapter 9. SNPs of TLRs and Bladder Cancer -- Chapter 10. Role of genetic polymorphisms in Lung Cancer.
    Abstract: This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.
    Type of Medium: Online Resource
    Pages: XXI, 339 p. 48 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813366992
    URL: https://doi.org/10.1007/978-981-33-6699-2
    DOI: 10.1007/978-981-33-6699-2
    DDC: 571.978
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    Invasive Species in Forests and Rangelands of the United States : A Comprehensive Science Synthesis for the United States Forest Sector (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Environment. ; Ecology . ; Landscape ecology. ; Ecosystems. ; Environmental Sciences. ; Terrestial Ecology. ; Landscape Ecology. ; Ecology.
    Description / Table of Contents: Chapter 1. Introduction (Deborah C. Hayes, Becky K. Kerns, Toral Patel-Weynand, and Deborah M. Finch) -- Chapter 2. Impacts of Invasive Species in Terrestrial and Aquatic Systems in the United States (Albert E. Mayfield III, Steven J. Seybold, Wendell R. Haag, M. Tracy Johnson, Becky K. Kerns, John C. Kilgo, Daniel J. Larkin, Rima D. Lucardi, Bruce D. Moltzan, Dean E. Pearson, John D. Rothlisberger, Jeffrey D. Schardt, Michael K. Schwartz, and Michael K. Young) -- Chapter 3. Impacts of Invasive Species on Forest and Grassland Ecosystem Processes in the United States (Chelcy Ford Miniat, Jennifer M. Fraterrigo, Steven T. Brantley, Mac A. Callaham, Jr., Susan Cordell, Jeffrey S. Dukes, Christian P. Giardina, Shibu Jose, and Gary Lovett) -- Chapter 4. Effects of Climate Change on Invasive Species (Deborah M. Finch, Jack L. Butler, Justin B. Runyon, Christopher J. Fettig, Francis F. Kilkenny, Shibu Jose, Susan J. Frankel, Samuel A. Cushman, Richard C. Cobb, Jeffrey S. Dukes, Jeffrey A. Hicke, and Sybill K. Amelon) -- Chapter 5. Invasive Species Response to Natural and Anthropogenic Disturbance (Susan E. Meyer, Mac A. Callaham, Jr., Jane E. Stewart, and Steven D. Warren) -- Chapter 6. Early Intervention Strategies for Invasive Species Management: Connections Between Risk Assessment, Prevention Efforts, Eradication, and Other Rapid Responses (Robert C. Venette, Doria R. Gordon, Jennifer Juzwik, Frank H. Koch, Andrew M. Liebhold, Robert K.D. Peterson, Sharlene E. Sing, and Denys Yemshanov) -- Chapter 7. Management of Landscapes for Established Invasive Species (Therese M. Poland, Jennifer Juzwik, Allen Rowley, Cynthia D. Huebner, John C. Kilgo, Vanessa M. Lopez, Deanna H. Olson, Dean Pearson, Robert Progar, Robert Rabaglia, John D. Rothlisberger, Justin B. Runyon, and Sharlene E. Sing) -- Chapter 8. Restoration of Landscapes and Habitats Affected by Established Invasive Species (Jennifer Koch, Dean E. Pearson, Cynthia D. Huebner, Michael K. Young, and Richard A. Sniezko) -- Chapter 9. Sectoral Impacts of Invasive Species in the United States and Approaches to Management (Anne S. Marsh, Deborah C. Hayes, Patrice N. Klein, Nicole Zimmerman, Alison Dalsimer, Douglas A. Burkett, Cynthia D. Huebner, Robert Rabaglia, Laura A. Meyerson, Bonnie L. Harper-Lore, Jamie L. Davidson, Marla R. Emery, Travis Warziniack, Rebecca Flitcroft, Becky K. Kerns, and Vanessa M. Lopez) -- Chapter 10. Inventory and Monitoring of Invasive Species (Sonja Oswalt, Chris Oswalt, Alycia Crall, Robert Rabaglia, Michael Schwartz, and Becky K. Kerns) -- Chapter 11. Tools and Technologies for Quantifying Spread and Impacts of Invasive Species (Matt Reeves, Inés Ibáñez, Dana Blumenthal, Gang Chen, Qinfeng Guo, Catherine Jarnevich, Jennifer Koch, Frank Sapio, Michael K. Schwartz, Bruce K. Wylie, and Stephen Boyte) -- Chapter 12. Social and Cultural Dynamics of Non-Native Invasive Species (John Schelhas, Janice Alexander, Mark Brunson, Tommy Cabe, Alycia Crall, Michael J. Dockry, Marla R. Emery, Susan J. Frankel, Nina Hapner, Caleb R. Hickman, Rebecca Jordan, Michael J. LaVoie, Zhao Ma, Ross K. Meentemeyer, Joe Starinchak, and Jelena Vukomanovic) -- Chapter 13. The Role of International Cooperation in Invasive Species Research (Andrew Liebhold, Faith Campbell, Doria R. Gordon, Qinfeng Guo, Nathan Havill, Bradley Kinder, Richard MacKenzie, David R. Lance, Dean Pearson, Sharlene E. Sing, Travis Warziniack, Robert C. Venette, and Denys Yemshanov) -- Chapter 14. Economics of Invasive Species (Travis Warziniack, Robert G. Haight, Denys Yemshanov, Jenny L. Apriesnig, Thomas P. Holmes, Amanda M. Countryman, John D. Rothlisberger, and Christopher Haberland) -- Chapter 15. Legislation and Policy (Faith T. Campbell, Hilda Diaz-Soltero, and Deborah C. Hayes) -- Chapter 16. Future Invasive Species Research Challenges and Opportunities (Becky K. Kerns, Therese M. Poland, Robert C. Venette, Toral Patel-Weynand, Deborah M. Finch, Allen Rowley, Deborah C. Hayes, Mike Ielmini) -- APPENDIX 1: Regional Summaries.
    Abstract: This open access book describes the serious threat of invasive species to native ecosystems. Invasive species have caused and will continue to cause enormous ecological and economic damage with ever increasing world trade. This multi-disciplinary book, written by over 100 national experts, presents the latest research on a wide range of natural science and social science fields that explore the ecology, impacts, and practical tools for management of invasive species. It covers species of all taxonomic groups from insects and pathogens, to plants, vertebrates, and aquatic organisms that impact a diversity of habitats in forests, rangelands and grasslands of the United States. It is well-illustrated, provides summaries of the most important invasive species and issues impacting all regions of the country, and includes a comprehensive primary reference list for each topic. This scientific synthesis provides the cultural, economic, scientific and social context for addressing environmental challenges posed by invasive species and will be a valuable resource for scholars, policy makers, natural resource managers and practitioners.
    Type of Medium: Online Resource
    Pages: XLII, 455 p. 87 illus., 67 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030453671
    URL: https://doi.org/10.1007/978-3-030-45367-1
    DOI: 10.1007/978-3-030-45367-1
    DDC: 577
    Language: English
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    Spatial Modeling and Assessment of Environmental Contaminants : Risk Assessment and Remediation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Environmental monitoring. ; Environmental management. ; Environmental chemistry. ; Pollution. ; Ecosystems. ; Environmental Monitoring. ; Environmental Management. ; Environmental Chemistry. ; Pollution.
    Description / Table of Contents: Part I. Soil and Sediment Contaminants, Risk Assessment and Remediation -- Chapter 1. Introduction to Part I: Soil and Sediment Contaminants, Risk Assessment and Remediation -- Chapter 2. Combating Arsenic Pollution in Soil Environment via Alternate Agricultural Land Use -- Chapter 3. Temporal and Seasonal Variation in Leachate Pollution Index (LPI) in Sanitary Landfill Sites- A Case study of Baidyabati landfill, West Bengal, India -- Chapter 4.Quantification of Landfill Gas Emission and Energy Recovery Potential: A Comparative Assessment of LandGEM and MTM Model for Kolkata -- Chapter 5. Assessment of natural enrichment of heavy minerals along coastal placers of India: Role of lake and river mouth embayment and its implications -- Chapter 6. Assessment the Impact of Plastic Contaminated Fertilizers on Agricultural Soil Health: A Case Study in Memari II C.D.Block, Purba Bardhaman,West Bengal, India -- Chapter 7. Determining the Role of Leaf Relative Water Content and Soil Cation Exchange Capacity in Phytoextraction Process – Using Regression Modelling -- Chapter 8. Phytoremediation of Arsenic using Allium sativum as Model System -- Chapter 9. Spatio-temporal analysis of open waste dumping sites using Google Earth: A case study of Kharagpur City, India -- Part II. Water Contaminants, Risk Assessment and Remediation -- Chapter 10. Introduction to Part II: Water Contaminants, Risk Assessment and Remediation -- Chapter 11. Groundwater Arsenic Contamination Zone based on geospatial modeling, risk and remediation -- Chapter 12. Geospatial assessment of surface water pollution and industrial activities in Ibadan, Nigeria -- Chapter 13. Aquaculture-based water quality assessment and risk remediationalong the Rasulpur River belt, West Bengal -- Chapter 14. Heavy Metal Contamination in Groundwater and Impact on Plant and Human -- Chapter 15. Emerging Threats of Microplastic contaminant in freshwater environment -- Chapter 16. Exploring Particle Size Transport Variability of Suspended Sediments in two Alpine Catchments over the Lesser Himalayan Region, India -- Chapter 17. Salinity and corrosion potential of groundwater in Mewat district of Haryana, India -- Chapter 18. Threats to quality in the coasts of the Black Sea: heavy metal pollution of seawater, sediment, macro-algae and sea-grass -- Chapter 19. Geospatial assessment of groundwater quality for drinking through Water Quality Index and Human Health Risk Index in an upland area of Chotanagpur Plateau of West Bengal, India -- Chapter 20. Existence of Pharmaceuticals and Personal Care Products (PPCPs) in the conventional water treatment process -- Chapter 21. Arsenic-rich surface and groundwater around eastern parts of Rupnagar district, Punjab, India -- Part III. Environmental Contaminants, Impacts and Sustainable Management -- Chapter 22. Introduction to Part III: Environmental Contaminants, Risk Assessment and Remediation -- Chapter 23. Dynamics of ultra-fine particles in indoor and outdoor environments: a modelling approach to study the evolution of particle characteristics -- Chapter 24. Environmental impacts of coal-mining and coal-fired power-plant activities in a developing country with global context -- Chapter 25. Overview of Indoor air pollution: A human health perspective -- Chapter 26. Mineralogy and Morphological characterization of Technogenic Magnetic Particles (TMP) from industrial dust: Insights into environmental implications -- Chapter 27. Pesticides: Recent Updates on Types Toxicity and Bioremediation Strategies -- Chapter 28. Commonly available plant neem (Azadirachtaindica A. Juss) ameliorates dimethoate induced toxicity in climbing perch Anabas testudineus -- Chapter 29. Estimating Particulate Matter concentrations from MODIS AOD considering meteorological parameters using Random Forest Algorithm -- Chapter 30 Bio-monitoring and bioremediation of a trans-boundary river in India: Functional roles of benthic mollusks and fungi -- Chapter 31 Assessing the Maximum Aerobic Biodegradation Potential of Leaf Litter, an Organic Fraction of Municipal Solid Waste, Under Optimum Nutrient Conditions -- Chapter 32. Rising trend of air pollution and its decadal consequences on meteorology and thermal comfort over Gangetic West Bengal, India.
    Abstract: This book demonstrates the measurement, monitoring and mapping of environmental contaminants in soil & sediment, surface & groundwater and atmosphere. This book explores state-of-art techniques based on methodological and modeling in modern geospatial techniques specifically focusing on the recent trends in data mining techniques and robust modeling. It also presents modifications of and improvements to existing control technologies for remediation of environmental contaminants. In addition, it includes three separate sections on contaminants, risk assessment and remediation of different existing and emerging pollutants. It covers major topics such as: Radioactive Wastes, Solid and Hazardous Wastes, Heavy Metal Contaminants, Arsenic Contaminants, Microplastic Pollution, Microbiology of Soil and Sediments, Soil Salinity and Sodicity, Aquatic Ecotoxicity Assessment, Fluoride Contamination, Hydrochemistry, Geochemistry, Indoor Pollution and Human Health aspects. The content of this book will be of interest to researchers, professionals, and policymakers whose work involves environmental contaminants and related solutions.
    Type of Medium: Online Resource
    Pages: XX, 720 p. 225 illus., 185 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030634223
    Series Statement: Environmental Challenges and Solutions,
    URL: https://doi.org/10.1007/978-3-030-63422-3
    DOI: 10.1007/978-3-030-63422-3
    DDC: 577
    Language: English
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    Fire Ecology and Management: Past, Present, and Future of US Forested Ecosystems (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Forestry. ; Physical geography. ; Applied ecology. ; Ecology . ; Ecosystems. ; Forestry. ; Earth System Sciences. ; Applied Ecology. ; Terrestial Ecology.
    Description / Table of Contents: Chapter 1. Introduction to Fire Ecology across USA Forested Ecosystems: Past, Present, and Future (Cathryn H. Greenberg, Beverly S. Collins, Scott Goodrick, Michael C. Stambaugh, and Gary R. Wein) -- Chapter 2. The Role of Fire in the Dynamics of Piedmont Vegetation (Joanna Spooner, Robert K. Peet, Michael P. Schafale, Alan S. Weakley and Thomas R. Wentworth) -- Chapter 3. Fire Ecology and Fire Management of Southeastern Coastal Plain Pine Ecosystems (Jeff S. Glitzenstein, J. Stephen Brewer, Ronald. E. Masters, J. Morgan Varner, and J. Kevin Hiers) -- Chapter 4. Fire Ecology and Management in Eastern Broadleaf and Appalachian Forests (Mary A. Arthur, J. Morgan Varner, Charles W. Lafon, Heather D. Alexander, Daniel C. Dey, Craig A. Harper, Sally P. Horn, Todd F. Hutchinson, Tara L. Keyser, Marcus A. Lashley, Christopher E. Moorman, and Callie J. Schweitzer) -- Chapter 5. Fire Ecology and Management of Forest Ecosystems in the Western Central Hardwoods and Prairie-Forest Border (Michael C. Stambaugh, Benjamin O. Knapp, and Daniel C. Dey) -- Chapter 6. Fire in Floodplain Forests of the Southeastern USA hy (Paul R. Gagnon, Loretta L. Battaglia, Brice B. Hanberry, William H. Conner, and Sammy L. King) -- Chapter 7. History and Future of Fire in Hardwood and Conifer Forests of the Great Lakes-Northeastern Forest Region, USA(Lee E. Frelich, Craig G. Lorimer, and Michael C. Stambaugh) -- Chapter 8. Fire Ecology of Rocky Mountain Forests(Sharon M. Hood, Brian J. Harvey, Paula J. Fornwalt, Cameron E. Naficy, Winslow D. Hansen, Kimberley T. Davis, Mike A. Battaglia, Camille Stevens-Rumann, Victoria Saab) -- Chapter 9. Fire Ecology of the North American Mediterranean-Climate Zone(Hugh D. Safford, Ramona J. Butz, Gabrielle N. Bohlman, Michelle Coppoletta, Becky L. Estes, Shana E. Gross, Kyle E. Merriam, Marc D. Meyer, Nicole A. Molinari, and Amarina Wuenschel) -- Chapter 10. Fire Ecology and Management in Pacific Northwest Forests(Matthew J. Reilly, Jessica E. Halofsky, Meg A. Krawchuk, Daniel C. Donato, Paul F. Hessburg, James Johnston, Andrew Merschel, Mark E. Swanson, Joshua S. Halofsky, and Thomas A. Spies) -- Chapter 11. Fire Ecology and Management of Southwestern Forests(Peter Z. Fulé, Catrin M. Edgeley, Carol L. Chambers, Serra Hoagland, Blanca Céspedes) -- Chapter 12. Fire and Forests in the 21st Century: Managing Resilience under Changing Climates and Fire Regimes in USA Forests(James M. Vose, David L. Peterson, Christopher J. Fettig, Jessica E. Halofsky, J. Kevin Hiers, Robert E. Keane, Rachel Loehman, and Michael C. Stambaugh).
    Abstract: This edited volume presents original scientific research and knowledge synthesis covering the past, present, and potential future fire ecology of major US forest types, with implications for forest management in a changing climate. The editors and authors highlight broad patterns among ecoregions and forest types, as well as detailed information for individual ecoregions, for fire frequencies and severities, fire effects on tree mortality and regeneration, and levels of fire-dependency by plant and animal communities. The foreword addresses emerging ecological and fire management challenges for forests, in relation to sustainable development goals as highlighted in recent government reports. An introductory chapter highlights patterns of variation in frequencies, severities, scales, and spatial patterns of fire across ecoregions and among forested ecosystems across the US in relation to climate, fuels, topography and soils, ignition sources (lightning or anthropogenic), and vegetation. Separate chapters by respected experts delve into the fire ecology of major forest types within US ecoregions, with a focus on the level of plant and animal fire-dependency, and the role of fire in maintaining forest composition and structure. The regional chapters also include discussion of historic natural (lightning-ignited) and anthropogenic (Native American; settlers) fire regimes, current fire regimes as influenced by recent decades of fire suppression and land use history, and fire management in relation to ecosystem integrity and restoration, wildfire threat, and climate change. The summary chapter combines the major points of each chapter, in a synthesis of US-wide fire ecology and forest management into the future. This book provides current, organized, readily accessible information for the conservation community, land managers, scientists, students and educators, and others interested in how fire behaviour and effects on structure and composition differ among ecoregions and forest types, and what that means for forest management today and in the future. .
    Type of Medium: Online Resource
    Pages: XVII, 502 p. 71 illus., 65 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030732677
    Series Statement: Managing Forest Ecosystems, 39
    URL: https://doi.org/10.1007/978-3-030-73267-7
    DOI: 10.1007/978-3-030-73267-7
    DDC: 577
    Language: English
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    Dietary Research and Cancer (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Biology. ; Cancer Treatment. ; Biotechnology. ; Molecular biology. ; Physiology. ; Cancer Biology. ; Biological Sciences. ; Cancer Therapy. ; Biotechnology. ; Molecular Biology. ; Physiology.
    Description / Table of Contents: Chapter 1. Introduction to Dietary Research and Cancer -- Chapter 2. Healthy Dietary Patterns and Cancer -- Chapter 3. Frequently Asked Diet and Nutrition Related Questions by Cancer Survivors -- Chapter 4. Dietary Recommendations of Worldwide Cancer Related Organizations -- Chapter 5. Outcome of ‘Diet and Cancer’ Related Clinical Trials -- 6. Diet and Cancer Epigenetics: A Step Towards Developing Cancer Epigenetic Diet -- 7. Role of Dietary Ingredients on Expression of Oncogenic and Tumor Suppressor miRNA -- 8. Can Diet Influence Metastasis? -- 9. Impact of Dietary Interventions on Cancer Stem Cells -- 10. Interaction of Dietary Metabolites with Anti-cancer Drug Targets -- 11. Revisiting the Anticancer Drug-Food Interactions -- 12. Functional Foods, Nutraceuticals, and Dietary Supplements in Cancer Prevention -- 13. Do Antioxidants Really Help Cancer Patients? The Puzzle of Benefits and Perils -- 14. Market of Dietary Supplements: Analysis of Health Benefits and Risk in Cancer -- 15. Cancer and Fasting: Can Fasting/Calorie Restriction (CR) or Fasting Mimicking Diet (FMD) Helps Fight Cancer? Molecular Basis of Fasting Response -- 16. Do Fasting, CR, and FMD Improves the Chemotherapy Response, Reduce Off Target Toxicities and Enhance Antitumor Immunity? Illusion or Clinical Reality? -- 17. Future Prospectus of Dietary Interventions in the Integrated Management of Cancer.
    Abstract: This book reviews all important aspects of dietary research associated with cancer with the aim of shedding new light on these conditions through combined understanding of traditional and new paradigms. The book is divided into 17 chapters, the first portion reinterprets healthy diets for cancer based on up-to-date evidence from a network science perspective, examining the dietary patterns, outcome of diet related clinical trials, emerging framework of molecular mechanisms and interactions of dietary interventions and their applications in personalized diet, ground realities of benefits and regulatory frame work for functional foods, nutraceuticals and supplements in cancer prevention and upcoming future prospectus in diet-cancer research.. The later part of the book discusses recent advances in understanding of the elaborative discourse on cancer and fasting, covering, for example, calorie restriction and fasting mimicking diet. Finally, different Dietary research and approaches are considered in the context of novel intervention for cancer research. Dietary Research in Cancer will be of interest for all researchers, nutritionists, students and clinicians in the field.
    Type of Medium: Online Resource
    Pages: XX, 197 p. 57 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811660504
    URL: https://doi.org/10.1007/978-981-16-6050-4
    DOI: 10.1007/978-981-16-6050-4
    DDC: 571.978
    Language: English
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    Diseases at the Wildlife - Livestock Interface : Research and Perspectives in a Changing World (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Agriculture. ; Zoology. ; Veterinary medicine. ; Epidemiology. ; Ecology. ; Agriculture. ; Zoology. ; Veterinary Science. ; Epidemiology.
    Description / Table of Contents: Part 1 Introduction -- 1 Host Community Interfaces: The Wildlife-Livestock -- 2 Natural And Historical Overview Of The Animal Wildlife-Livestock Interface -- 3 The Ecology Of Pathogens Transmission At The Wildlife-Livestock Interface: Beyond Disease Ecology, Towards Socio-Ecological System Health -- Part 2 Regional Perspectives Of Disease At The Wildlife-Livestock Interface -- 4 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Europe -- 5 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Asia -- 6 Characteristics And Perspectives Of Disease At Wildlife-Livestock Interface In Africa -- 7 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Oceania -- 8 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In North America -- 9 Characteristics And Perspectives Of Disease At The Wildlife-Livestock Interface In Central And South America -- Part 3 Characterization Of The Wildlife-Livestock Interface -- 10 Collecting Data To Assess The Interactions Between Livestock And Wildlife -- 11 Characterization Of Wildlife-Livestock Interfaces: The Need For Interdisciplinary Approaches And A Dedicated Thematic Field -- 12 Quantifying Transmission Between Wild And Domestic Populations -- Part 4 Synthesis And Conclusions -- 13 Synthesis And Future Perspectives Of The Study And Management Of Diseases At The Wildlife-Livestock Interface.
    Abstract: Shared diseases among wildlife, livestock and humans, often transboundary, are relevant to public health and global economy, as being highlighted currently relative to the global COVID19 pandemic. Diseases at these interfaces also impact the conservation of biodiversity and must be considered when managing wildlife. While wildlife and domestic livestock have coexisted in dynamic systems for thousands of years, spillover disease risks are higher today than in the past due to global patterns of increasing close contact and interactions among wildlife, livestock and humans in the context of complex, diverse and numerous circumstances. Multidisciplinary studies of animal interfaces, especially those involving wildlife, therefore, must be brought to the forefront so that knowledge gaps can be realized and filled to inform managers and policy makers. In the first part of the book authors illustrate and discuss ecological and epidemiological concepts related to the interfaces, with a vision towards socio-ecological system health. In addition, the history of past animal interfaces provides the necessary perspective to focus current questions, better understand present situations, and informs how we can best approach the future. The second part discusses the myriad of similar and differing wildlife- livestock interfaces found around the world from a regional point of view. The third part focuses on how to assess the spatial and temporal overlap between livestock and wildlife, and authors present new technical innovations about how inter-transmissions between wild and domestic populations can be quantified. An overview of main modeling approaches available to quantify multi-host disease transmission at the wildlife/livestock interface, illustrated with specific-case studies, is also presented. Finally, the need for interdisciplinary approaches and a dedicated thematic field to approach the wildlife/livestock interfaces and create opportunities to promote wildlife–livestock coexistence is emphasized. The concluding chapter presents perspectives and directions to better understanding disease dynamics at the wildlife/livestock interface, global change and implications for the future. The changing distribution of interfaces, ongoing human and environmental changes (e. g. climate warming, changes in animal production systems, etc.) and their likely impacts and consequences for the interfaces and disease transmission processes are all discussed.
    Type of Medium: Online Resource
    Pages: XVI, 421 p. 77 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030653651
    Series Statement: Wildlife Research Monographs, 3
    URL: https://doi.org/10.1007/978-3-030-65365-1
    DOI: 10.1007/978-3-030-65365-1
    DDC: 577
    Language: English
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    Life at High Pressure : In the Deep Sea and Other Environments (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Life sciences. ; Physiology. ; Biodiversity. ; Biomechanics. ; Biophysics. ; Ecology. ; Life Sciences. ; Physiology. ; Biodiversity. ; Biomechanics. ; Biophysics.
    Description / Table of Contents: High pressure and High pressure environments -- High pressure: molecules, chemical processes and cellular structures -- The high pressure micro-environment of vertebrate load bearing joints- Effects of high pressure on the activity of ordinary animals, including humans, and on the function of their excitable cells and ion channels -- The effects of decompression and subsequent re-compression on the activity of deep sea animals and eukaryote cells. The isobaric collection of deep sea animals.-Molecular adaptation to high pressure: proteins in deep sea animals -- Molecular adaptation to high pressure: membranes -- Prokaryotes at high pressure in the Oceans and the Deep Biosphere -- Hydrothermal vents: the inhabitants, their way of life and their adaptation to high pressure -- Buoyancy at depth -- Divers: Air breathing animals, including humans, at high pressure -- Adaptation to high pressure in the laboratory -- High pressure equipment used in the laboratory, at sea and at depth.
    Abstract: The book discusses the ways in which high hydrostatic pressure (i.e. water pressure) affects all grades of life which thrive at pressures much greater those in our normal environment. The deep sea is the best known high pressure environment, where pressures reach a thousand times greater than those at the surface, yet it is populated by a variety of animals and microorganisms. The earth’s crust supports microorganisms which live in water filled pores at high pressure. In addition, the load bearing joints of animals like ourselves experience pulses of hydrostatic pressure of a magnitude similar to the pressure at mid ocean depths. These pressures affect molecular structures and biochemical reactions. Basic cellular processes are drastically affected – the growth and division of cells, the way nerves conduct impulses and the chemical reactions which provide energy. Adaptation to high pressure also occurs in complex physiological systems such as those which provide buoyancy. Probably the greatest challenge to our understanding of adaptation to high pressure is the stabilisation of the nervous system of deep sea animals to avoid convulsions which pressure causes in shallow water animals. Additionally the book provides insight into the engineering required to study life at high pressure: equipment which can trap small deep sea animals and retrieve them at their high pressure, equivalent equipment for microorganisms, laboratory microscopes which can focus on living cells under high pressure, incubators for bacteria which require high pressure to grow, high pressure aquaria for marine animals and lastly and briefly, manned and unmanned submersible vessels, Landers and deep drill hole sampling. Rather like the organisms studied many laboratory instruments have been adapted to function at high pressure.
    Type of Medium: Online Resource
    Pages: XVII, 445 p. 62 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030675875
    URL: https://doi.org/10.1007/978-3-030-67587-5
    DOI: 10.1007/978-3-030-67587-5
    DDC: 577
    Language: English
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    Social-Ecological Systems (SES) : From Risks and Insecurity to Viability and Resilience (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Bioclimatology. ; Environmental sciences Social aspects. ; Risk management. ; Social policy. ; Environment. ; Ecology. ; Climate Change Ecology. ; Environmental Social Sciences. ; IT Risk Management. ; Social Policy. ; Environmental Sciences.
    Description / Table of Contents: Preface and Introduction -- Part I Risks and Impacts Enhancing the Vulnerability of Social-Ecological Systems -- Part II Environmental and Climate Change Impacts on Social-Ecological Systems – Conflict, Inequality and Human Security -- Part III Human Mobility and Social-Ecological Systems -- Part IV Enhancing the Sustainability and Resilience of Social-Ecological Systems – Some Recommended Paths -- Conclusions.
    Abstract: This book contributes to the multidisciplinary debate about social–ecological systems (SES) within the perspective of rethinking the nature of interaction between these systems, especially in the Anthropocene Era. Most chapters either deliberate on risk dynamics threatening current SES or stimulate thought processes to manage such risks and related negative implications. After analyzing the main drivers of SES vulnerability, the book highlights the shifts to be made to enhance the sustainability and resilience of these systems, mainly the integration and restructuring of governance frameworks, the reorganization of production and consumption systems far from conventional models based on consumerism, the elaboration of mitigation, adaptation, and SDGs implementation measures from a co-benefit perspective, and the consideration of appropriate approaches and paradigms while elaborating and implementing response mechanisms. This volume is relevant to researchers/experts, students, practitioners, and decision-makers from different scales and spheres.
    Type of Medium: Online Resource
    Pages: XXXII, 265 p. 43 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030762476
    URL: https://doi.org/10.1007/978-3-030-76247-6
    DOI: 10.1007/978-3-030-76247-6
    DDC: 577
    Language: English
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    Ethology and Behavioral Ecology of Sea Otters and Polar Bears (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Ecology . ; Conservation biology. ; Zoology. ; Biodiversity. ; Ecology. ; Conservation Biology. ; Zoology. ; Biodiversity.
    Description / Table of Contents: Introduction -- Part I. Ethology and Behavioral Ecology of Sea Otters -- Taxonomy and Evolution of Sea Otters -- Sea Otter Behavior: Morphologic, Physiologic, and Sensory Adaptations -- Sea Otter Foraging Behavior -- Social Structure of Marine Otters: Inter and Intraspecific Variation -- Reproductive Behavior of Male Sea Otters -- Reproductive Behavior of Female Sea Otters and Their Pups -- Sea Otter Behavior and Its Influence on Littoral Community Structure -- Sea Otter Predator Avoidance Behavior -- Sea Otters and the Maritime Fur Trade -- Part II. Ethology and Behavioral Ecology of Polar Bears -- Polar Bear Taxonomy and Evolution -- Polar Bear Behavior: Morphologic and Physiologic Adaptations -- Polar Bear Foraging Behavior -- Polar Bear Reproductive and Denning Behavior -- Polar Bear Maternal Care, Neonatal Development, and Social Behavior -- Polar Bear Behavior in Response to Climate Change -- Human-Polar Bear Interactions.
    Abstract: Sea otters and polar bears are carnivorous marine mammals that still resemble their terrestrial ancestors. Compared with Cetacea (whales and dolphins), Sirenia (dugongs and manatees), and Pinnipedia (seals, sea lions, and walrus), they are less adapted for an aquatic life and the most recently evolved among marine mammals. Sea otters are amphibious but seldom come ashore, and polar bears primarily occur on sea ice or along the shore. When at sea, both species spend most of their time swimming at the surface or making short, shallow dives when foraging or pursuing prey. Indeed, polar bears rarely pursue seals in water. Nevertheless, polar bears are powerful swimmers and will stalk seals from the water. As with many other large carnivores, they are solitary hunters. Although sea otters are gregarious and form aggregations at sea called rafts, they are primarily asocial. Except during mating, the principal interaction among sea otters occurs between a female and offspring during the six-month dependency period. In large carnivores (e.g., wolves and lions) that feed on ungulates, sociality and cooperation are favored because of the need to capture large prey and defend carcasses. Polar bears, which are the largest terrestrial carnivore, are solitary hunters of seals and are neither gregarious nor social. Males and females briefly associate during courtship and mating. During this time, males aggressively compete for females. At other times, males generally avoid each other except for aggregations of males that form while summering on land, and females with cubs avoid males, which are known for infanticide. As with sea otters, the interaction of polar bears outside of mating occurs between a female and her offspring during the 2-3 year dependency period. This interaction is critically important when altricial cubs are born in the winter den. This book provides new insight into the ethology and behavioral ecology of sea otters and polar bears. Each chapter reviews the discoveries of previous studies and integrates recent research using new techniques and technology. The authors also address historic and current anthropogenic challenges for their survival as climate change alters entire marine ecosystems.
    Type of Medium: Online Resource
    Pages: XIV, 363 p. 110 illus., 89 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030667962
    Series Statement: Ethology and Behavioral Ecology of Marine Mammals,
    URL: https://doi.org/10.1007/978-3-030-66796-2
    DOI: 10.1007/978-3-030-66796-2
    DDC: 577
    Language: English
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    Anoikis : How the Extracellular Matrix Regulates Life-or-Death Decisions (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cell death. ; Cancer Biology. ; Cell Death.
    Description / Table of Contents: Preface -- Introduction -- The intersection of anoikis resistance and fatty acid metabolism in cancer -- Anoikis resistance in melanoma -- Anoikis mediated by stress-activated MAPK signaling pathways -- Metabolic Regulation of Anoikis -- Metabolic Reprogramming contributes to Anoikis resistance in Cancer Cells -- Role of the nuclear receptors in anoikis -- The roles of anoikis in cervical cancer -- Shc and the control of small GTPase dynamics in cellular anchorage -- Anoikis and the Human Gut Epithelium in Health and Disease -- Epithelial cell extrusion: the prelude to anoikis -- Microtubule modifications and mitochondria: role in anoikis.
    Abstract: This book provides a useful resource for graduate-level cancer cell biology courses. Since the first report, in 1994, of “anoikis”—the apoptosis that occurs when cells lack appropriate contact with the extracellular matrix—over 2,100 papers have been published on this subject. This book is the first comprehensive, in-depth and up-to-date compendium on anoikis. Chapters are authored by some of the leading researchers in the field. This book provides both mechanistic and translational information regarding anoikis, in a convenient format. Mechanistically, the following topics will be addressed in detail: The role of MAP kinase signaling The role of Shc proteins as cellular anchorage sensors The role of cellular metabolism, and fatty acid metabolism in particular, and how they are affected by oncogenic transformation How epithelial cell extrusion – the prelude to anoikis—is regulated in normal and cancer cells The convergence of TGF-b and androgen receptor signaling in the regulation of anoikis This book also discusses the specialized functions and dysregulation of anoikis in the following cancer settings: Colon cancer Melanoma Cervical cancer The book serves to update i nvestigators actively working on problems in the anoikis field, in either experimental or translational settings. For investigators encountering novel biological phenomena that might relate to anoikis, it serve as an entry point to the literature that does not require an extensive background in cell adhesion signaling or apoptosis mechanisms. .
    Type of Medium: Online Resource
    Pages: VIII, 202 p. 6 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030738563
    URL: https://doi.org/10.1007/978-3-030-73856-3
    DOI: 10.1007/978-3-030-73856-3
    DDC: 571.978
    Language: English
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    Marine Coastal Ecosystems Modelling and Conservation : Latin American Experiences (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Freshwater ecology. ; Marine ecology. ; Environmental sciences Social aspects. ; Animal culture. ; Conservation biology. ; Ecology . ; Ecosystems. ; Freshwater and Marine Ecology. ; Environmental Social Sciences. ; Animal Science. ; Conservation Biology.
    Description / Table of Contents: SECTION I. Natural and human environment of coastal ecosystems -- Chapter 1. Ecological modelling and conservation on the coasts of Mexico -- Chapter 2. SE Pacific: the ecosystem and its use along the Chilean and Peruvian coast -- SECTION II. Marine ecosystem models in the South East Pacific coast -- Chapter 3. Modelling the Northern Humboldt Current Ecosystem; from winds to predators -- Chapter 4. Marine ecosystem models in the South Pacific coast -- Chapter 5. Keystone Species Complexes and macroscopic properties for improving ecosystem-based conservation practices in kelp forest along the north-central Chilean coast -- Chapter 6. Exploring alternative management policies for benthic ecological systems of northern Chile (SE Pacific) -- SECTION III. Central Pacific, Caribbean and Atlantic coastal ecosystem models -- Chapter 7. How much biomass must remain at the sea after fishing to conserve ecosystem -- functioning? The case of the Monterey sardine in the Gulf of California, Mexico -- Chapter 8. Dynamic and spatial model of the coral reef of Banco Chinchorro Biosphere Reserve (Caribbean Sea) for assessment harvest scenarios: short-term responses -- Chapter 9. Ecological role of sharks assessed by Ecopath models -- SECTION IV. System-based conservation and management: conclusions -- Chapter 10. Graph theory in food webs: uses and applications for conservation of marine ecosystems -- Chapter 11. Modelling aim the conservation of coastal marine ecosystem in Latin America.
    Abstract: The book presents a collection of large-scale network-modeling studies on coastal systems in Latin America. It includes a novel description of the functioning of coastal complex ecosystems and also predicts how natural and human-made disturbances percolate through the networks. Coastal areas belong to the most populated ecosystems around the globe, and are massively influenced by human impacts such as shipping, mining, fisheries, tourism, pollution and human settlements. Even though many of these activities have facilitated socio-economic development, they have also caused a significant deterioration in natural populations, communities and ecosystems worldwide. Covering coastal marine ecosystems of Latin America such as the NE and SE Pacific, NW Atlantic and Caribbean areas, it discusses the construction of quantitative (Ecopath-Ecosim-Ecospace and Centrality of Node Sets) and semi-quantitative (Loop Analysis) multispecies trophic-network models to describe and assess the impacts of natural and human interventions like pelagic and benthic fishing as well as natural events such as El Niño, and La Niña. The book also features steady state (and/or near moving equilibrium) and dynamical models to support the management of exploited organisms, and applies and quantifies macroscopic indices, based on Ascendency (Ulanowicz) and Local Stability (Levins´ Loop Analysis). Further, it discusses the determination of the Keystone Species Complex Index, which is a holistic extension of the classical concept of Keystone Species (Paine), offering novel strategies for conservation monitoring and management.
    Type of Medium: Online Resource
    Pages: X, 207 p. 41 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030582111
    URL: https://doi.org/10.1007/978-3-030-58211-1
    DOI: 10.1007/978-3-030-58211-1
    DDC: 577
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    Inflammation, Infection, and Microbiome in Cancers : Evidence, Mechanisms, and Implications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Human physiology. ; Immunology. ; Cancer Biology. ; Medical Microbiology. ; Biomedical Research. ; Human Physiology. ; Immunology.
    Description / Table of Contents: Chapter 1: The Microbiome And The Hallmarks Of Cancer -- Chapter 2: Microbiome In Human GI Cancers -- Chapter 3: The Gut Microbiome And Colorectal Cancer -- Chapter 4: Salmonella Infection In Human Cancers -- Chapter 5: Biomarkers Of Esophageal Cancers And Precancerous Lesions -- Chapter 6: Epithelial And Immune Cell Responses To Helicobacter Pylori That Shape The Gastric Tumor Microenvironment -- Chapter 7: Microbiome And Liver Cancer -- Chapter 8: THE MICROBIOME AND UROLOGIC CANCERS -- Chapter 9: Role Of Infections And Tissue Inflammation In The Pathology Of The Fallopian Tube And High-Grade Serous Ovarian Cancer -- Chapter 10: Commensal Microbes And Their Metabolites: Influence On Host Pathways In Health And Disease -- Chapter 11: Dietary And Microbiome In Cancer Prevention -- Chapter 12: Autophagy And Cancer-Current Biology And Drug Development -- Chapter 13: Mitochondrial Regulation Of Inflammation In Cancer -- Chapter 14: Modern Germ-Free Study Designs And Emerging Static Housing Technology In A Growing ‘Human Microbiome’ Market -- Chapter 15: Machine Learning In Identification Of Disease-Associated Microbiota -- Chapter 16: Mediation Analysis Of Microbiome Data And Detection Of Causality In Microbiome Studies.
    Abstract: This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.
    Type of Medium: Online Resource
    Pages: XII, 509 p. 31 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030679514
    Series Statement: Physiology in Health and Disease,
    URL: https://doi.org/10.1007/978-3-030-67951-4
    DOI: 10.1007/978-3-030-67951-4
    DDC: 571.978
    Language: English
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    Ecosystem Services in Patagonia : A Multi-Criteria Approach for an Integrated Assessment (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Applied ecology. ; Conservation biology. ; Ecology . ; Biodiversity. ; Freshwater ecology. ; Marine ecology. ; Ecosystems. ; Applied Ecology. ; Conservation Biology. ; Biodiversity. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Chapter 1 - Ecosystem services as a tool for decision-making in Patagonia -- Chapter 2- Assessment of provisioning ecosystem services in terrestrial ecosystems of Santa Cruz province, Argentina -- Chapter 3 - Grazing management and provision of ecosystem services in Patagonian arid rangelands -- Chapter 4 - Synergies and trade-offs among ecosystem services and biodiversity in different forest types inside and off-reserve in Tierra del Fuego, Argentina -- Chapter 5 - Shrubland management in northwestern Patagonia: an evaluation of its short-term effects on multiple ecosystem services -- Chapter 6 - Silvopastoral systems in northern Argentine-Chilean Andean Patagonia: Ecosystem services provision in a complex territory -- Chapter 7 - Ecosystem services values of the northwestern Patagonian natural grasslands -- Chapter 8 - The ecosystem services provided by peatlands in Patagonia -- Chapter 9 - Restoration for provision of ecosystem services in Patagonia-Aysén, Chile -- Chapter 10 - The North American beaver invasion and the impact over the ecosystem services in the Tierra del Fuego archipelago -- Chapter 11 - Social links for a nexus approach from an ecosystem services perspective in Central-East Patagonia -- Chapter 12 - Salmon farming: is it possible to relate its impact to the waste remediation ecosystem service? -- Chapter 13 - Using the ecosystem services approach to understand the distributional effects of marine protected areas in the Chilean Patagonia -- Chapter 14 - Socio-cultural valuation of ecosystem services in Southern Patagonia, Argentina -- Chapter 15 - Looking beyond ecosystem services supply: co-production and access barriers in marine ecosystems of the Chilean Patagonia -- Chapter 16 - Ecosystem services and human well-being: a comparison of two Patagonian social-ecological systems -- Chapter 17 - Urban Planning In Arid Northern Patagonia Cities To Maximize Local Ecosystem Services Provision -- Chapter 18 - Land size, native forests and ecosystem services inequalities in the rural Chilean Patagonia -- Chapter 19 - Imaginaries, transformations and resistances in Patagonian territories from a socio-ecological perspective -- Chapter 20 - The challenges of implementing ecosystem services in the Argentinean and Chilean Patagonia -- Chapter 21 - Natural capital and local employment in Argentine Patagonia -- Chapter 22 - Ecosystem services in Patagonia: a synthesis and future directions. .
    Abstract: This book aims to quantify and discuss how societies have directly and indirectly benefited from ecosystem services in Patagonia; not only in terms of provisioning and cultural services, but also regulating and supporting services. Patagonia, a region that stretches across two countries (ca. 10% in Chile and 90% in Argentina), is home to some of the most extensive wilderness areas on our planet. Natural grasslands comprise almost 30% of the Americas, including the Patagonian steppe, while Patagonian southern temperate forests are important for carbon sequestration and storage, play a pivotal role in water regulation, and have become widely recognized for their ecotourism value. However, profound changes are now underway that could affect key ecosystem functions and ultimately human well-being. In this context, one major challenge we face in Patagonia is that ecosystem services are often ignored in economic markets, government policies and land management practices. The book explores the synergies and trade-offs between conservation and economic development as natural landscapes and seascapes continue to degrade in Patagonia. Historically, economic markets have largely focused on the provisioning services (forest products, livestock) while neglecting the interdependent roles of regulating services (erosion and climate control), supporting services (nutrient cycling) and cultural services (recreation, local identity, tourism). Therefore, the present work focuses on ecosystem functions and ecosystem services, as well as on trends in biodiversity and the interactions between natural environments and land-use activities throughout Patagonia.
    Type of Medium: Online Resource
    Pages: VII, 501 p. 85 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030691660
    Series Statement: Natural and Social Sciences of Patagonia,
    URL: https://doi.org/10.1007/978-3-030-69166-0
    DOI: 10.1007/978-3-030-69166-0
    DDC: 577
    Language: English
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    Histone Mutations and Cancer (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Molecular genetics. ; Proteins . ; Cancer Biology. ; Molecular Genetics. ; Protein Biochemistry.
    Description / Table of Contents: Chapter 1: Overview of histone modification -- Chapter 2: The histone H3 family and its deposition pathways -- Chapter 3: Histone H3K27M Mutation in Brain Tumors -- Chapter 4: Histone Mutations and Bone Cancers -- Chapter 5: Histone H3G34 mutation in brain and bone tumors -- Chapter 6: Epigenetic-targeted treatments for H3K27M-mutant midline gliomas -- Chapter 7: Histone lysine to methionine mutation as anti-cancer drug target.
    Abstract: This book focuses on histone mutations, especially those mutations closely related to cancer. Genetic mutations and epigenetic alterations contribute to the development of a variety of cancers: recent genetic studies have identified e.g. H3K27M and H3G34R/V mutation in over 75% of DIPG cases, H3.3K36M mutation in more than 90% of chondroblastoma cases, and H3G34W/L mutation in over 90% of giant cell tumors of bone. Given the high incidence and tumorigenesis effects of histone H3 mutations, they are also referred to as oncohistones. This book highlights the advances made in the area over the past 10 years, and offers a state-of-the-art summary of epigenetic alternation, gene expression, protein structure, drug discovery, immunotherapy, and mouse modeling of histone H3 mutations in various tumors. Chiefly intended to provide researchers and graduate students with an overall picture of these mutations, it will also be of interest to researchers in basic oncology, clinical oncology, and epigenetics, as well as academics and clinical oncology practitioners.
    Type of Medium: Online Resource
    Pages: VII, 96 p. 17 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581045
    Series Statement: Advances in Experimental Medicine and Biology, 1283
    URL: https://doi.org/10.1007/978-981-15-8104-5
    DOI: 10.1007/978-981-15-8104-5
    DDC: 571.978
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    Role of Exosomes in Biological Communication Systems (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Human physiology. ; Diseases. ; Oncology. ; Regenerative medicine. ; Cancer Biology. ; Human Physiology. ; Diseases. ; Oncology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Chapter 1. Isolation and characterization of extracellular vesicles: classical and modern approaches -- Chapter 2. Characterization and fine structure of exosomes -- Chapter 3. Extracellular vesicles mediate the embryonic-maternal paracrine communication -- Chapter 4. The interplay between oviduct-derived exosomes and cumulus-oocyte complexes -- Chapter 5. The interplay between exosomes and spermatozoa -- Chapter 6. Mesenchymal stem cell-derived exosomes and regenerative medicine -- Chapter 7. Therapeutic Potential of Mesenchymal Stem/Stromal Cell Derived-Exosomes -- Chapter 8. Exosomes in Neurodegenerative Disorders -- Chapter 9. Differential expression of exosomal microRNAs in neurodegenerative diseases -- Chapter 10. Urinary exosomes as a possible source of kidney disease biomarkers -- Chapter 11. Extracellular vesicles as potential therapeutic targets and biomarkers for liver disease -- Chapter 12. Implications of extracellular vesicles in blood protozoan parasitic diseases -- Chapter 13. Cancer cells-derived Exosomes and Metastasis -- Chapter 14. Extracellular vesicles and integrins: partners in cancer progression -- Chapter 15. Exosomes: the crucial element in the prostate cancer -- Chapter 16. Exosomal microRNAs: Potential Biomarkers for Cancer Diagnosis, Treatment Response, and Prognosis -- Chapter 17. Exosomes in drug delivery -- Chapter 18. Exosomes and Supported Lipid Layers as Advanced Naturally Derived Drug Delivery Systems.
    Abstract: This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.
    Type of Medium: Online Resource
    Pages: XII, 373 p. 34 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811565991
    URL: https://doi.org/10.1007/978-981-15-6599-1
    DOI: 10.1007/978-981-15-6599-1
    DDC: 571.978
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    Cancer Metabolomics : Methods and Applications (2021)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Cancer Biology. ; Biomedical Research.
    Description / Table of Contents: 1. NMR-Based Metabolomics in Cancer Research -- 2. Capillary Electrophoresis–Mass Spectrometry for Cancer Metabolomics -- 3. Chemical Isotope Labeling LC-MS for Metabolomics -- 4. Single cell metabolomics by mass spectrometry imaging -- 5. Fatty Acid Metabolism and Cancer -- 6. Metabolomics of Gastric Cancer -- 7. HIF-1α metabolic pathways in human cancer -- 8. Regulation of glycolysis in head and neck cancer -- 9. Metabolomics of oral/head and neck cancer -- 10. Ion chromatography with mass spectrometry for metabolomic analysis -- 11. Methods of lipidomic analysis: Extraction, derivatization, separation and identification of lipids -- 12. Functional metabolomics and chemoproteomics approaches reveal novel metabolic targets for anti-cancer therapy -- 13. Metabolomics of glioma -- 14. Microbial metabolomics: From methods to translational applications -- 15. Advances in the study of N6-methyladenine in eukaryotes -- 16. NMR Based Metabolomics -- 17. Quantitative analysis of oncometabolite 2-hydroxyglutarate -- 18. Tracer-based Cancer Metabolomic Analysis -- 19. Mass spectrometry-based shotgun lipidomics for cancer research -- 20. Comprehensive Two-dimensional Gas Chromatography Mass Spectrometry-based Metabolomics.
    Abstract: Cancer metabolomics is a rapidly evolving field that aims for a comprehensive dissection of the metabolic phenotypes and functional network of metabolites in human cancers. State of the art metabolomics tools have been developed and applied to studying cancer metabolism and developing metabolic targets for improved diagnosis, prognosis and therapeutic treatment of human cancers. Chapters are written by subject experts in the field of cancer metabolomics with cross-disciplinary contributions. Coverage includes advanced metabolomics technologies and methodologies, including chemical isotope labelling liquid chromatography - mass spectrometry, capillary ion chromatography - mass spectrometry, 2-D gas chromatography – mass spectrometry, capillary electrophoresis – mass spectrometry, nuclear magnetic resonance spectroscopy, shotgun lipidomics, tracer-based metabolomics, microbial metabolomics, mass spectrometry imaging for single cell metabolomics and functional metabolomics. In addition, the book highlights new discoveries in cancer metabolism such as hypoxia inducible factor pathway, isocitrate dehydrogenase 1 mutation and oncometabolites. Finally, contributors focus on the translational applications of metabolomics in human cancers such as glioma, head and neck cancer, and gastric cancer. This new volume will be a unique reference source for cancer researchers and promote applications of metabolomics in understanding cancer metabolism.
    Type of Medium: Online Resource
    Pages: XV, 312 p. 80 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030516529
    Series Statement: Advances in Experimental Medicine and Biology, 1280
    URL: https://doi.org/10.1007/978-3-030-51652-9
    DOI: 10.1007/978-3-030-51652-9
    DDC: 571.978
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    Resistance to Targeted Therapies in Multiple Myeloma (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Immunology. ; Cancer Biology. ; Immunology.
    Description / Table of Contents: 1. The role of targeted therapy in multiple myeloma -- 2. Lenalidomide -- 3. Pomalidomide -- 4. Mechanisms driving resistance to proteasome inhibitors bortezomib, carfilzomib and ixazomib in multiple myeloma -- 5. Daratumumab -- 6. Elotuzumab -- 7. Histone deacetylase inhibitors -- 8. Bone targeted therapies -- 9. New targeted therapies for multiple myeloma under clinical investigation.
    Abstract: Multiple Myeloma remains an incurable malignancy. As the disease progresses, it invariably becomes resistant to treatment and almost all patients develop refractory disease. There are multiple different types of targeted therapies and many of them are used in combination at different stages of disease. Targeted therapies that are approved to be used include Proteasome Inhibitors, Immunomodulatory Drugs and Monoclonal Antibodies. Second and third generations of these drugs are developed to overcome resistance and they have unique mechanism of actions. Targeted therapies that are undergoing clinical trials include CAR-T cells, bi-specific antibodies, vaccines, ubiquitin ligase inhibitors and BCL-2 inhibitors. This book will help to develop an understanding of targeted therapies in Multiple Myeloma. Its goal is to provide a unique review of the mechanism of action and resistance of the many targeted therapies in Multiple Myeloma by leaders of the field. The book will be useful for students in medical science, clinicians, health professionals, scientists, pharmaceutical professionals, drug developers, and policy makers. This book will provide an insightful knowledge of the biology of Multiple Myeloma, the mechanism of action and resistance of targeted therapies, application of biomarkers and genomics and possible strategies in overcoming resistance and future development.
    Type of Medium: Online Resource
    Pages: XVII, 154 p. 5 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030734404
    Series Statement: Resistance to Targeted Anti-Cancer Therapeutics, 22
    URL: https://doi.org/10.1007/978-3-030-73440-4
    DOI: 10.1007/978-3-030-73440-4
    DDC: 571.978
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    Notch Signaling in Embryology and Cancer : Notch Signaling in Cancer (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Embryology. ; Cancer Biology. ; Cell Biology. ; Embryology.
    Description / Table of Contents: Notch signaling in prevention ant therapy: fighting cancer with a two-sided sword -- Transcription factor RBPJ as a molecular switch in regulating the Notch response -- Unraveling of Hidden Secrets: The tumour suppressor Lethal (2) giant discs (Lgd)/CC2D1, Notch Signaling and Cancer -- Notch and endometrial cancer -- Notch and Esophageal Squamous Cell Carcinoma -- Notch signaling and liver cancer -- Notch inHead and Neck Cancer -- Notch Signaling and Human Papillomavirus-Associated Oral Tumorigenesis -- The impact of Notch signalingfor carcinogenesis and progression of non-melanoma skin cancer: lessons learned fromcancer stem cells, tumor angiogenesis, and beyond -- Notch Signaling in Thyroid Cancer -- The Relevance of Notch Signaling in Cancer Progression -- Notch Signaling and the Breast Cancer Microenvironment -- Notch pathway: a journey from notching phenotypes to cancer immunotherapy -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books -- Notch Signaling and Embryologic Development and Molecular Basis of Notch Signaling – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
    Type of Medium: Online Resource
    Pages: XVII, 228 p. 28 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030550318
    Series Statement: Advances in Experimental Medicine and Biology, 1287
    URL: https://doi.org/10.1007/978-3-030-55031-8
    DOI: 10.1007/978-3-030-55031-8
    DDC: 571.978
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    Emerging Trends in Nanomedicine (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Cancer. ; Regenerative medicine. ; Medicine Research. ; Biology Research. ; Microtechnology. ; Microelectromechanical systems. ; Cancer Biology. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Research. ; Microsystems and MEMS.
    Description / Table of Contents: Chapter 1. Strategies to improve oral delivery of natural anticancer molecules -- Chapter 2. Nanoparticles catalyzing enzymatic reactions: recent developments and future prospects -- Chapter 3. Biogenic silver nanoparticles: A potent therapeutic agent -- Chapter 4. Translational studies of nanofibers-based scaffold for skin and bone tissue regeneration -- Chapter 5. Functional Dendritic Coatings for Biomedical Implants -- Chapter 6. Application of nanotherapeutics for combating human protozoan parasitic infections.
    Abstract: This book illustrates the significance of nanotechnology in the delivery of anticancer and antimicrobial drugs, biomimetic technologies, tissue engineering, sensing, diagnostics, and artificial enzymes. It first briefly discusses the use of nanotechnology for the delivery of anticancer medications, and the concept and applications of catalytically active nanomaterial-based artificial enzymes for sensing and diagnostic applications. It then explores the use of silver nanoparticle-based novel antimicrobials, and comprehensively reviews the role of nanomaterials in developing biomedical implants and tissue engineering applications. Lastly, it offers a detailed description of nanotherapeutics for combating human protozoan parasitic infections. Cutting across the disciplines, this book serves as a guide for researchers and scientists in biotechnology, medical science and material science.
    Type of Medium: Online Resource
    Pages: XIV, 240 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811599200
    URL: https://doi.org/10.1007/978-981-15-9920-0
    DOI: 10.1007/978-981-15-9920-0
    DDC: 571.978
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  • 95
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    Online Resource
    Biomarkers and Biosensors for Cervical Cancer Diagnosis (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Tumor markers. ; Medical screening. ; Materials. ; Detectors. ; Cancer Biology. ; Tumour Biomarkers. ; Cancer Screening. ; Sensors and biosensors.
    Description / Table of Contents: Chapter 1. An Introduction to Cancer Biomarkers -- Chapter 2. Cervical Cancer -- Chapter 3. Potential Biomarkers for Early Diagnosis of Cervical Cancer -- Chapter 4. Methods for Screening of Cervical Cancer: State of Art -- Chapter 5. Electrochemical DNA Biosensors for Cervical Cancers -- Chapter 6. Optical DNA based Sensors for Cervical Cancers -- Chapter 7. Other Biosensors for Cervical Cancer Detection.
    Abstract: This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as vibrational spectroscopy and polymerase chain reaction techniques for the diagnosis of cervical cancer. Finally, it reviews currently available biomarkers for the early diagnosis of cervical cancer and presents strategies for developing novel biomarkers based on cellular and molecular approaches. As such, this book is a comprehensive resource for researchers and clinicians working in cervical cancer diagnostics.
    Type of Medium: Online Resource
    Pages: IX, 115 p. 18 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811625862
    URL: https://doi.org/10.1007/978-981-16-2586-2
    DOI: 10.1007/978-981-16-2586-2
    DDC: 571.978
    Language: English
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  • 96
    Online Resource
    Online Resource
    Pines and Their Mixed Forest Ecosystems in the Mediterranean Basin (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Forestry. ; Applied ecology. ; Plant ecology. ; Ecosystems. ; Forestry. ; Applied Ecology. ; Plant Ecology.
    Description / Table of Contents: Foreword -- Preface -- PART I: Evolution, genetics and distribution -- 1. Phylogenesis and evolution -- 2. Population genetics and genomics -- 3. Conservation and breeding -- 4 Biogeography and local adaptations -- 5. Mediterranean pines as invasive species -- PART II: Ecophysiology of Mediterranean pines: resistance to stress and perturbation -- 6. Physiological trade-offs under stress and perturbation -- 7. Carbon allocation dynamics under stress -- 8 -- Root systems under drought -- 9. Stress and tree mortality -- 10. Forest diseases affecting pines -- 11. Resistance to herbivorous insects -- PART III: Pine and mixed forest ecosystems under global climate change -- 12. Growth and vigor -- 13. Forest distribution resilience under climate change -- 14. Carbon and energy balance -- 15. Soil properties and biogeochemical functioning -- 16. Decomposition -- PART IV: Forest dynamics, biodiversity and biotic interactions -- 17. Dynamics of mixed pine-oak forests -- 18. Bird diversity -- 19 Soil micro- and macrofauna -- 20. Mycorhizae -- PART V: Forest fire ecology and management -- 21. Fire past present and future -- 22. Adaptations to fire -- 23. Post-fire soil erosion -- 24. The impact of grazing on understory fuel load -- 25. Post fire restoration -- 26. Predicting post-fire conifer regeneration in California -- 27. Remote sensing fire damage -- PART VI: Policy and Ecosystem services of Mediterranean pine and mixed forest ecosystems -- 28. Mediterranean forests and the United Nations sustainable development goals -- 29. Ecosystem services -- 30.Multi-disciplinary assessment of cultural ecosystem services supplied by Mediterranean pine and mixed forests -- PART VII: Afforestation and forest management policy -- 31. Dynamics and management of western Mediterranean pinewoods -- 32. From pine monoculture forests into sustainable mixed forest ecosystems -- 33. Forest policy in Israel -- 34. Water based forest management.
    Abstract: Almost 20 years after the first MEDPINE book "Ecology, biogeography and management of Pinus halepensis and P. brutia forest ecosystems in the Mediterranean basin "(Ne'eman and Trabaud, 2000) was published, this new book presents up to date and state of the art scientific knowledge and information. It covers a wide range of topics concerning Mediterranean pine trees growing in natural and planted forests, their ecosystems and management. This book will be an essential source for learning, exploring, planning and managing Mediterranean pine and mixed pine-broadleaved forests. It includes mostly review chapters contributed by leading scientists, foresters and managers. It covers: genetics and adaptation, distribution and evolution, ecophysiology and drought resistance, function of pine and mixed forest ecosystems, forest dynamics, biodiversity and biotic interactions, fire ecology, afforestation and management, ecosystem services and policy - all under the effect of global climate change. While forests are studied mainly in temperate and tropical climate zones, looking at Mediterranean forests of sub-humid to semi-arid regions is important more than ever due to current global climate trends. This collection can serve as a scientific textbook for students of biology, agriculture and forestry, researchers of ecology, forestry and related fields, forest managers, policy and decision makers.
    Type of Medium: Online Resource
    Pages: XXIII, 746 p. 185 illus., 129 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030636258
    Series Statement: Managing Forest Ecosystems, 38
    URL: https://doi.org/10.1007/978-3-030-63625-8
    DOI: 10.1007/978-3-030-63625-8
    DDC: 577
    Language: English
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  • 97
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    Online Resource
    Tumor Microenvironment : Novel Concepts (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Cancer Microenvironment. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: 1. The Tumour Microenvironment and Circulating Tumour Cells: A partnership driving metastasis and glycan-based opportunities for cancer control -- 2. Dormancy in the Tumor Microenvironment -- 3. Tumor-associated tertiary lymphoid structures: A cancer biomarker and a target for next-generation immunotherapy -- 4. Studying the tumor microenvironment in zebrafish -- 5. Pre-metastatic niche formation by neutrophils in different organs -- 6. Tumor cell invasion and the tumor microenvironment: Special focus on brain tumors -- 7. The dog as a model to study the tumor microenvironment -- 8. EFFEROCYTOSIS AND THE STORY OF “FIND ME’’, ‘’EAT ME” AND “DON’T EAT ME” SIGNALING IN THE TUMOR MICRO ENVIRONMENT -- 9. Color-coded imaging of the tumor micro-environment (TME) in human patient-derived orthotopic xenograft (PDOX) mouse models -- 10. Mitochondria and the tumor microenvironment in blood cancer -- 11. Telocytes in the tumor microenvironment -- 12. Modeling the roles of astrocytes in the metastatic tumor cell microenvironment -- 13. Roles of fibroblasts in microenvironment formation associated with radiation-induced cancer -- 14. Tumor microenvironment-associated pericyte populations may impact therapeutic response in thyroid cancer -- 15. The adrenergic nerve network in cancer -- 16. Current treatment modalities targeting tumor microenvironment in castration-resistant prostate cancer -- 17.Brain metastases and tumor microenvironment -- 18. MIGRATION STIMULATING FACTOR (MSF). ITS ROLE IN THE TUMOUR -- MICROENVIRONMENT -- 19. Mechanical Signaling in the Mammary Microenvironment - from Homeostasis to Cancer -- 20. Osteopontin Signaling in Shaping Tumor Microenvironment Conducive to Malignant Progression -- 21. Progesterone receptor signaling in the breast tumor microenvironment -- 22. Progranulin/GP88, a complex and multi-faceted player of tumor growth by direct action and via the tumor microenvironmen -- 23. Sex-based differences in the tumor microenvironmet. .
    Abstract: This volume discusses novel concepts in cancer biology, focusing on different factors that affect the tumor microenvironment. Topics covered include sex-based differences in the tumor microenironment, dormancy in the tumor microenvironment, the influence of obesity on the tumor microenvironment, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Novel Concepts covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 548 p. 79 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030731199
    Series Statement: Advances in Experimental Medicine and Biology, 1329
    URL: https://doi.org/10.1007/978-3-030-73119-9
    DOI: 10.1007/978-3-030-73119-9
    DDC: 571.978
    Language: English
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  • 98
    Online Resource
    Online Resource
    Tumor Microenvironment : The Role of Chemokines – Part B (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Proteins . ; Internal medicine. ; Cancer Microenvironment. ; Cancer Biology. ; Cell Biology. ; Protein Biochemistry. ; Internal Medicine.
    Description / Table of Contents: CCL2 in the tumor microenvironment -- CXCL3 signaling in the tumor microenvironment -- CXCL8 Signaling in the Tumor Microenvironment -- CXCL11 signaling in the tumor microenvironment -- CXCL12 signaling in the tumor microenvironment -- CXCL13 signaling in the tumor microenvironment -- CCL24 signaling in the tumor microenvironment -- CCL25 signaling in the tumor microenvironment -- CCL27 signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment. Each chapter focuses on the chemokines patterns of expression, their regulation, and their roles in immune cell recruitment, as well as how they affect cancer immunity and tumorigenesis. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Chemokines – Part Bupdates us on what we know about various aspects of the tumor microenvironment, as well as apprises us on future directions in the field. This book is essential reading for advanced cell biology and cancer biology students as well as scientists seeking an update on recent developments and research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: IX, 139 p. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030626587
    Series Statement: Advances in Experimental Medicine and Biology, 1302
    URL: https://doi.org/10.1007/978-3-030-62658-7
    DOI: 10.1007/978-3-030-62658-7
    DDC: 571.978
    Language: English
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  • 99
    Online Resource
    Online Resource
    The Future of Prevention and Treatment of Breast Cancer (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Cancer Biology. ; Biomedical Research.
    Description / Table of Contents: 1. Defining breast cancer -- 2: Breast Cancer Recurrence and Survival -- 3: Synopsis of the Treatment of Breast Cancer -- 4: The Present Treatment of Hereditary Breast Cancer -- 5: Basis for the Epigenetic Treatment of Triple Negative Breast Cancer -- 6: A New Treatment Strategy foe BRCA1 Related Breast Cancer -- 7: Present Options in the Prevention of Breast Cancer -- 8: The Physiological Basis of Breast Cancer Prevention -- 9: The Present and Future of Screening in Breast Cancer Prevention -- 10: A Vision of the Future.
    Abstract: The objective of this book is to provide a critical analysis of the present prevention strategies for breast cancer, emphasizing the cost benefits and quality of life of the patient. Rooted in the present knowledge of breast cancer biology and prevention and treatment options, the book will describe the future tools that could be available to oncologists and how these new approaches may change the landscape of recurrence and survival of the disease. Special emphasis will be given to the prevention strategies counterposing the present limitations and conflicting prevention guidelines for both hereditary and preventive non-hereditary breast cancer, and propose how the implementation of new strategies based on the present knowledge could save millions of lives and be more cost efficient. The book will present a critical status of the treatment and prevention of breast cancer and detail how a quantum leap could be achieved in the field by applying present basic research knowledge to clinical application.
    Type of Medium: Online Resource
    Pages: XI, 192 p. 41 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030728151
    URL: https://doi.org/10.1007/978-3-030-72815-1
    DOI: 10.1007/978-3-030-72815-1
    DDC: 571.978
    Language: English
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  • 100
    Online Resource
    Online Resource
    The Andean Cloud Forest (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotic communities. ; Biodiversity. ; Plant ecology. ; Animal migration. ; Ecosystems. ; Biodiversity. ; Plant Ecology. ; Animal Migration.
    Description / Table of Contents: 1. Introduction: Randall W. Myster -- 2. Dynamics of Andean Treeline Ecotones: Between Cloud Forest and Páramo Geocritical Tropes. Fausto O. Sarmiento -- 3. ANÁLISIS REGIONAL EN ECOSISTEMAS DE MONTAÑA EN COLOMBIA:Una mirada desde la funcionalidad del paisaje y los servicios ecosistémicos. Paola Isaacs-Cubides, Julián Díaz and Tobias Leyva-Pinto -- 4. Ecohydrology of Tropical Andean Cloud Forests. Conrado Tobon Martin -- 5. Litterfall in Andean forests: Quantity, composition, and environmental drivers. Wolfgang Wilcke -- 6. Arbuscular Mycorrhizal Fungi and Ectomycorrhizas in the Andean Cloud Forest of South Ecuador. Ingeborg Haug, Sabrina Setaro, Juan Pablo Suárez -- 7. Nesting ecology of the Tucuman Amazon (Amazona tucumana) in the cloud forest of Northwestern Argentina. Luis Rivera and Natalia Politi -- 8. Adaptive strategies of frugivore bats to Andean cloud forests. Adriana Ruiz and Pascual J. Soriano -- 9. Diversification and dispersal of Neotropical fauna: Processes and patterns in Andean species diversity. Juan C. Garcia-Ramirez and Angela M. Mendoza-Henao -- 10. Mapping Hydrological Ecosystem Services and Impacts of Scenarios for Deforestation and Conservation of Lowland, Montane and Cloud-Affected Forests. Mark Mulligan -- 11. Randall W. Myster. Conclusions, synthesis and future directions.
    Abstract: A book focused solely on Andean Cloud Forests (ACF) has never been published. ACF are high biodiversity ecosystems in the Neotropics with a large proportion of endemic species, and are important for the hydrology of entire regions. They provide water for large parts of the Amazon basin, for example. Here I take advantage of my many years working in ACF in Ecuador, to edit this book that contains the following sections: (1) ACF over space and time, (2) Hydrology, (3) Light and the Carbon cycle, (4) Soil, litter, fungi and nutrient cycling, (5) Plants, (6) Animals, and (7) Human impacts and management. Under this premise, international experts contributed chapters that consist of reviews of what is known about their topic, of what research they have done, and of what needs to be done in the future. This work is suitable for graduate students, professors, scientists, and researcher-oriented managers.
    Type of Medium: Online Resource
    Pages: X, 223 p. 61 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030573447
    URL: https://doi.org/10.1007/978-3-030-57344-7
    DOI: 10.1007/978-3-030-57344-7
    DDC: 577
    Language: English
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