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  • 1
    Online Resource
    Online Resource
    Coronary Artery Disease: Therapeutics and Drug Discovery (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Description / Table of Contents: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Abstract: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Type of Medium: Online Resource
    Pages: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811525179
    Series Statement: Advances in Experimental Medicine and Biology, 1177
    URL: https://doi.org/10.1007/978-981-15-2517-9
    DOI: 10.1007/978-981-15-2517-9
    DDC: 615
    Language: English
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  • 2
    Online Resource
    Online Resource
    Pediatric Pharmacotherapy (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    URL: https://doi.org/10.1007/978-3-030-50494-6
    DOI: 10.1007/978-3-030-50494-6
    DDC: 615
    Language: English
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  • 3
    Online Resource
    Online Resource
    Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    URL: https://doi.org/10.1007/978-3-030-68510-2
    DOI: 10.1007/978-3-030-68510-2
    DDC: 615
    Language: English
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  • 4
    Online Resource
    Online Resource
    Organotypic Models in Drug Development (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Description / Table of Contents: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Abstract: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Type of Medium: Online Resource
    Pages: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030700638
    Series Statement: Handbook of Experimental Pharmacology, 265
    URL: https://doi.org/10.1007/978-3-030-70063-8
    DOI: 10.1007/978-3-030-70063-8
    DDC: 615
    Language: English
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  • 5
    Online Resource
    Online Resource
    Vaccination Strategies Against Highly Variable Pathogens (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human physiology. ; Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human Physiology.
    Description / Table of Contents: Successful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
    Abstract: Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .
    Type of Medium: Online Resource
    Pages: VII, 180 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030580049
    Series Statement: Current Topics in Microbiology and Immunology, 428
    URL: https://doi.org/10.1007/978-3-030-58004-9
    DOI: 10.1007/978-3-030-58004-9
    DDC: 615
    Language: English
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  • 6
    Online Resource
    Online Resource
    Drug Stability and Chemical Kinetics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: 1 Principles of pharmaceutical analysis in drug stability and chemical kinetics -- 2 Guidelines for drug stability and stability testing -- 3 Chemical kinetics and its applications in drug stability -- 4 Methods and protocols for drug stability studies -- 5 Physical basis of degradation of pharmaceutical products -- 6 Role of microbiological degradation on drug stability -- 7 Role of decomposition on drug stability -- 8 Role of catalysis in drug stability -- 9 Analytical techniques for the assessment of drug stability -- 10 Stability of pharmaceutical products -- 11 Role of kinetic models in drug stability -- 12 Stability studies of vaccines -- 13 Stability studies of proteinous compounds -- 14 Stability studies of extemporaneous pharmaceutical products -- 15 Stability studies of parenteral products -- 16 Stability studies of solid dosage forms.
    Abstract: This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. .
    Type of Medium: Online Resource
    Pages: XIV, 284 p. 22 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811564260
    URL: https://doi.org/10.1007/978-981-15-6426-0
    DOI: 10.1007/978-981-15-6426-0
    DDC: 615
    Language: English
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  • 7
    Online Resource
    Online Resource
    Handbook of 200 Medicinal Plants : A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Medicinal Chemistry.
    Description / Table of Contents: Abelmoschus maschatus -- Abrus precatorius -- Abutilon indicum -- Acacia catechu -- Acacia nilotica (A. arabica) -- Achillea millefolium -- Achyranthes aspera -- Aconitum napellus -- Acorus calamus -- Adiantum venustum (Adiantun capillus-veneris) -- Aegle marmelos -- Agrimonia eupatorium.-Alhagi maurorum -- Alkanna tinctoria -- Allium cepa -- Allium sativum -- Aloe vera -- Alpinia galangal -- Alpinia officinarum -- Alstonia scholaris -- Althaea officinalis -- Ammi majus -- Anacardium occidentale -- Anacyclus pyrethrum -- Andrographis paniculata -- Anethum graveolens -- Anthemis nobilis -- Apium graveolens -- Argemone Mexicana -- Aristolochia bracteolata -- Aristolochia fontanesii (A. longa) -- Aristolochia indica -- Aristolochia rotunda -- Artemisia absinthium -- Artemisia vulgaris -- Asparagus adscendens -- Asparagus officinalis -- Asparagus racemosus -- Atropa belladonna -- Azadirachta indica -- Bacopa monnieri -- Bauhinia tomentosa -- Berberis Aristata -- Berberis vulgaris -- Bombyx mori -- Borago officinalis -- Boswellia serrata -- Brassica nigra -- Butea monosperma -- Caccinia macranthera var. glauca (C. glauca) -- Caesalpinia bonduc (Caesalpinia bonducella) -- Cannabis sativa -- Capparis spinosa -- Cardiospermum halicacabum -- Carthamus tinctorius -- Carum carvi -- Cassia fistula -- Catharanthus roseus -- Celastrus paniculatus -- Centaurea behen -- Centella asiatica -- Chamaecrista absus (Cassia absus) -- Chamaemelum nobile (Anthemis nobilis) -- Cheilocostus speciosus (Costus Speciosus) -- Cichorium intybus -- Cinnamomum camphora -- Cinnamomum cassia -- Cinnamomum verum (C. zeylanicum) -- Citrullus colocynthis -- Clitoria ternatea -- Colchicum autumnale -- Colchicum luteum -- Commiphora gileadensis (C. opobalsamum) -- Commiphora myrrha -- Commiphora wightii (C. mukul) -- Convolvulus scammonia -- Cotoneaster nummularius -- Crocus sativus -- Croton tiglium -- Cullen corylifolium (Psoralea corylifolia) -- Cuminum cyminum -- Curcuma aromatica -- Curcuma longa -- Curcuma zedoaria -- Cuscuta chinensis -- Cuscuta reflexa -- Cydonia oblonga -- Cymbopogon schoenanthus -- Cyperus rotundus -- Datura stramonium -- Delphinium denudatum -- Dolichousnea longissimi (Usnea longissima) -- Doronicum pardalianches -- Embelia ribes -- Euphorbia hirta -- Euphorbia resinifera -- Ferula assa-foetida -- Ficus carica -- Ficus racemosa -- Foeniculum vulgare -- Fumaria officinalis -- Gentiana lutea -- Glycyrrhiza glabra -- Gymnema sylvestre -- Helleborus niger -- Hemidesmus Indicus -- Hibiscus rosa-sinensis -- Holarrhena pubescens (Holarrhena antidysenterica) -- Hyoscyamus niger -- Hyssopus officinalis -- Illicium verum -- Iris germanica -- Juniperus communi -- Justicia adhatoda (Adhatoda vasica) -- Lactuca sativa -- Lavandula stoechas -- Lawsonia inermis -- Lepidium sativum -- Linum usitatissimum -- Lupinus albus -- Malva sylvestris -- Marrubium vulgare -- Matricaria chamomilla -- Melia azedarach -- Melilotus officinalis -- Melissa officinalis -- Mesua ferrea -- Momordica charantia -- Moringa oleifera -- Myristica fragrans -- Myrtus communis -- Nageia nagi -- Nepeta cataria -- Nigella sativa -- Ocimum basilicum -- Ocimum gratissimum -- Ocimum tenuiflorum (Ocimum sanctum -- Operculina turpethum -- Paeonia emodi -- Pandanus odorifer (Pandanus Odoratissimus) -- Papaver somniferum -- Persicaria bistorta -- Phyllanthus emblica (Emblica officinalis) -- Picrorhiza kurroa -- Pimpinella anisum -- Piper cubeba -- Piper nigrum -- Pistacia lentiscus -- Plantago major -- Plantago ovata -- Plumbago zeylanica -- Polygonum aviculare -- Portulaca oleracea -- Quercus infectoria -- Rauvolfia serpentina -- Rheum emodi -- Rheum officinale -- Ricinus communis -- Rubia cordifolia -- Rumex vesicarius -- Ruta graveolens -- Salix caprea -- Salvia officinalis -- Santalum album -- Saussurea lappa -- Semecarpus anacardium -- Senna alexandrina -- Senna occidentalis -- Senna tora -- Sida cordifolia -- Smilax china;- Solanum americanum (S. nigrum) -- Sterculia urens -- Strychnos nux-vomica -- Swertia chirata -- Symplocos racemosa -- Syzygium cumini (Eugenia jambolana) -- Tamarindus indica -- Taraxacum officinale -- Taxus baccata -- Tephrosia purpurea -- Terminalia bellirica -- Terminalia chebula -- Thymus vulgaris -- Tinospora cordifolia -- Trachyspermum ammi (Ptychotis coptica) -- Tribulus terrestris -- Trigonella foenum-graecum -- Tussilago farfara -- Valeriana jatamansi (Nardostachys jatamansi) -- Verbena officinalis -- Vernonia anthelmintica (Baccharoides anthelmintica) -- Vigna unguiculata (Dolichos biflorus) -- Viola odorata -- Viscum album -- Withania somnifera -- Wrightia tinctoria -- Zingiber officinale -- Zingiber zerumbet -- Ziziphus jujuba -- Abbreviations -- Glossary -- Ayurvedic Terms of Diseases -- List of Referenced Books -- Index.
    Abstract: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.
    Type of Medium: Online Resource
    Pages: XXX, 2156 p. 199 illus., 198 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030168070
    URL: https://doi.org/10.1007/978-3-030-16807-0
    DOI: 10.1007/978-3-030-16807-0
    DDC: 615
    Language: English
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  • 8
    Online Resource
    Online Resource
    Therapeutic Applications of Dopamine D3 Receptor Function : New Insight After 30 Years Of Research (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Preface -- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction -- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System -- Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function -- Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression -- Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target -- Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinson’s Disease -- Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor -- Dopamine D3 Receptor in Stimulant and Opiate Use Disorders -- The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature -- The Dopamine D3 receptor in Food Addiction -- The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia -- D3 receptors and Restless Legs Syndrome -- D3 receptors and PET imaging.
    Abstract: The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
    Type of Medium: Online Resource
    Pages: VIII, 275 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031230585
    Series Statement: Current Topics in Behavioral Neurosciences, 60
    URL: https://doi.org/10.1007/978-3-031-23058-5
    DOI: 10.1007/978-3-031-23058-5
    DDC: 615
    Language: English
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  • 9
    Online Resource
    Online Resource
    Approaching Complex Diseases : Network-Based Pharmacology and Systems Approach in Bio-Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Description / Table of Contents: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Abstract: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Type of Medium: Online Resource
    Pages: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030328573
    Series Statement: Human Perspectives in Health Sciences and Technology, 2
    URL: https://doi.org/10.1007/978-3-030-32857-3
    DOI: 10.1007/978-3-030-32857-3
    DDC: 615
    Language: English
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  • 10
    Online Resource
    Online Resource
    Pharmacology of Potassium Channels (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Neurosciences. ; Pharmacology. ; Human Physiology. ; Neuroscience.
    Description / Table of Contents: Comparison of K+ Channel families -- High-resolution structures of K+ channels -- Pharmacological approaches to studying potassium channels -- Cardiac K+ channels and channelopathies -- Cardiac hERG K+ channel as safety and pharmacological target -- Pharmacology of A-type K+ channels -- Kv7 channels and hyperexcitability disorders -- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain -- Potassium channels in cancer -- Kir channel molecular physiology, pharmacology and therapeutic implications -- The pharmacology of ATP-sensitive K+ channels (KATP) -- Calcium-activated K+ channels (KCa) and therapeutic implications -- The Pharmacology of two-pore domain potassium channels -- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits -- Peptide toxins targeting KV channels -- Therapeutic antibodies targeting potassium ion channels.
    Abstract: The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .
    Type of Medium: Online Resource
    Pages: VIII, 545 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030840525
    Series Statement: Handbook of Experimental Pharmacology, 267
    URL: https://doi.org/10.1007/978-3-030-84052-5
    DOI: 10.1007/978-3-030-84052-5
    DDC: 615
    Language: English
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  • 11
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    Online Resource
    Nutritional Toxicology (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nutrition   . ; Food science. ; Pharmacology. ; Nutrition. ; Food Science.
    Description / Table of Contents: 1 Preface -- 2 Effects of Nutrients/nutrition on Toxicants/toxicity -- 3 Effects of Xenobiotics on Nutrition -- 4 Effects of Antinutritional Factors on the Digestibility, Bioavailability and Quality of Protein -- 5 Natural Toxicants Originating from Food/Diet -- 6 Food contaminants -- 7 Food additives -- 8 Food contact materials -- 9 Genetically modified food -- 10 Tolerable upper limits of nutrients -- 11 Risk assessment and Risk-benefit assessment -- 12 Nutrients/Nutrition and Drug Interaction -- 13 Phytochemicals and Health -- 14 Adverse Effects of Phytochemicals.
    Abstract: This book provides a broad overview of the chemicals in food that have the potential to induce adverse health effects. Nutritional Toxicology is an interaction of nutrition, toxicology, biochemistry and food science, etc. Its main research scope involves the effects of nutrients on metabolisms of toxicants and their mechanisms, the interaction of the toxicants and contaminants originated from diet with nutrients and nutrition process, the adverse health outcome of nutrients excess, as well as methodology of research and related food and nutrition regulation process. Also the risk assessment of toxicants and contaminants in foods, and risk benefit assessment of nutrients (dietary supplementation) has become an emerging topic. This book provides novel and provocative insights into the fields of nutrition, food science and toxicology. It also offers a state-of-the-art report on recent discoveries concerning nutritional toxicology and where the field is going. It mainly focuses on advances made over the past 20 years. It will benefit graduate students, researchers and food and nutrition related regulation parties.
    Type of Medium: Online Resource
    Pages: X, 384 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811908729
    URL: https://doi.org/10.1007/978-981-19-0872-9
    DOI: 10.1007/978-981-19-0872-9
    DDC: 615
    Language: English
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  • 12
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    Online Resource
    Network Pharmacology (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Pharmacy. ; Bioinformatics. ; Pharmacology. ; Pharmacy. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. 'Network Target' Theory and Network Pharmacology -- Chapter 2. Application of Network Pharmacology Based on Artificial Intelligence Algorithm in Drug R & D -- Chapter 3. Commonly used Network Pharmacology Database -- Chapter 4. Commonly used Network Pharmacology Software -- Chapter 5. Network Pharmacology and TCM Modernization Case Studies -- Chapter 6. Network Pharmacology and Modern Drug R & D Cases -- Chapter 7. Drug-based Network Pharmacology Practice Process -- Chapter 8. Disease-based Network Pharmacology Practice Process -- Chapter 9. Drug-disease-based Network Pharmacology Practice Process.
    Abstract: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
    Type of Medium: Online Resource
    Pages: XVII, 468 p. 163 illus., 119 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811607530
    URL: https://doi.org/10.1007/978-981-16-0753-0
    DOI: 10.1007/978-981-16-0753-0
    DDC: 615
    Language: English
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  • 13
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    Online Resource
    Environment and Female Reproductive Health (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Midwifery. ; Public health. ; Pharmacology. ; Midwifery. ; Public Health.
    Description / Table of Contents: Part I Environmental Harmful Factors -- 1 Introduction to Environmental Harmful Factors -- Part II Female Reproductive Processes and Diseases -- 2 Introduction of Female Reproductive Processes and Reproductive Diseases -- Part III Effects of Environmental Factors on Reproductive Process -- 3 The Influence of Environmental Factors on Ovarian Function, Follicular Genesis, and Oocyte Quality -- 4 Effects of environment and lifestyle factors on premature ovarian failure -- 5 Effects of Environment and Lifestyle Factors on Anovulatory Disorder -- 6 Effects of Cigarette Smoking on Preimplantation Embryo Development -- 7 Toxicical effects of BPDE on dysfunctions of female trophoblast cells -- 8 The Roles of Stress-Induced Immune Response in Female Reproduction -- 9 Effects of Environmental EDCs on Oocyte Quality, Embryo Development and the Outcome in Human IVF Process -- Part IV Effects of Environmental Factors on Reproductive Diseases -- 10 Effects of environmental endocrine-disrupting chemicals on female reproductive health -- 11 Definition and Multiple Factors of Recurrent Spontaneous Abortion -- 12 The Variations of Metabolic Detoxification Enzymes Lead to Recurrent Miscarriage and their Diagnosis Strategy -- Part V Effects of Environmental Factors on Fertility Preservation -- 13 The Effects of Negative Elements in Environment and Cancer on Female Reproductive System.
    Abstract: This book will focus on the harmful effect of environmental toxins on female reproductive health. Reproduction is the basis of the continuation of human beings, and environment is the basis of human survival. However, environmental pollution has become a potential risk factor for human reproductive health, which not only leads to many chronic diseases, but also causes certain harm to reproductive health. Compared to male reproduction, female reproductive process is more complex, the reproductive system is more fragile, and is more vulnerable to be damaged. The aim of this book is to review the research progress, to address the challenges, and to stimulate the development in the direction of environment and female reproductive health.
    Type of Medium: Online Resource
    Pages: XI, 313 p. 13 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813341876
    Series Statement: Advances in Experimental Medicine and Biology, 1300
    URL: https://doi.org/10.1007/978-981-33-4187-6
    DOI: 10.1007/978-981-33-4187-6
    DDC: 615
    Language: English
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  • 14
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    Online Resource
    Organic Cation Transporters in the Central Nervous System (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Molecular biology. ; Pharmacology. ; Human Physiology. ; Molecular Biology.
    Description / Table of Contents: General Overview of Organic Cation Transporters in Brain -- Organic Cation Transporter Expression and Function in the CNS -- Genetic and Epigenetic Regulation of Organic Cation Transporters -- Experimental Methods for Investigating Uptake 2 Processes In Vivo -- Substrates and inhibitors of OCTs and PMAT and therapeutic implications -- Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implications -- Organic Cation Transporters in Brain Catecholamine Homeostasis -- The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances -- Organic Cation Transporters in Psychiatric Disorders -- Organic Cation Transporters and Nongenomic Glucocorticoid Action -- Brain Plasma Membrane Monoamine Transporter in Health and Disease -- Regulation of Neurogenesis by Organic Cation Transporters: Potential Therapeutic Implications -- Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery.
    Abstract: Rapidly growing interest in the role of organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in central monoamine homeostasis makes this book especially timely, given its thematic alignment with the role of OCTs and PMAT in CNS. This book discusses latest insights into the field laying an emphasis on health, disease and therapeutics. The chapter, “General Overview of Organic Cation Transporters in Brain”, of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 328 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030829841
    Series Statement: Handbook of Experimental Pharmacology, 266
    URL: https://doi.org/10.1007/978-3-030-82984-1
    DOI: 10.1007/978-3-030-82984-1
    DDC: 615
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  • 15
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    Online Resource
    The Carbonic Anhydrases: Current and Emerging Therapeutic Targets (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Clinical biochemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Pharmacy.
    Description / Table of Contents: Dedication -- Preface.-The carbonic anhydrases in health and disease -- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets -- Targeting carbonic anhydrases in vascular and pulmonary disease -- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema -- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders -- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes -- An overview of carbonic anhydrase-related neoplasms -- The carbonic anhydrase IX interactome and the regulation of cancer progression -- Carbonic anhydrase IX: current and emerging therapies -- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents -- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening -- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.
    Abstract: This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians from many relevant disciplines within science and medicine.
    Type of Medium: Online Resource
    Pages: XII, 288 p. 38 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030795115
    Series Statement: Progress in Drug Research, 75
    URL: https://doi.org/10.1007/978-3-030-79511-5
    DOI: 10.1007/978-3-030-79511-5
    DDC: 615
    Language: English
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  • 16
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    Online Resource
    Pharmacology of the WNT Signaling System (2021)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Physiology. ; Oncology. ; Neurosciences. ; Developmental biology. ; Pharmacology. ; Physiology. ; Oncology. ; Neuroscience. ; Developmental Biology and Stem Cells.
    Description / Table of Contents: Pharmacological thinking in WNT signaling -- Controlling WNT Signaling Specificity and implications for targeting WNTs pharmacologically -- WNTs on exosomes -- Strategies to target LRPs in WNT signaling -- Targeting the receptor tyrosine kinase ROR1 by small molecules -- Assessing WNT binding and Frizzled activation employing genetically encoded, biophysical sensors -- Disheveled proteins as crucial mediators of WNT signaling -- Destruction complex and regulation of CTNNB1 -- Strategies to therapeutically target WNT/PCP like signaling in disease -- Mining natural compounds to target WNT signaling - from mushrooms to corals -- FZD7 as a therapeutic target in intestinal cancer -- Targeting oncogenic WNT signaling with WNT derived peptides -- Targeting WNT signaling in lung pathology -- The role of WNT signaling in osteoarthritis and the therapeutic potential of its pharmacological targeting -- WNT signaling in Alzheimers disease and other neurodegenerative disorders - opportunities for therapy? -- Targeting WNT signaling as a risk.
    Abstract: This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulation, tissue homeostasis and repair. Dysfunction of this evolutionarily conserved signaling system leads to many diseases including developmental disorders, diverse forms of cancer, fibrosis, neurodegenerative disease and many more. The WNT signaling system is built upon 19 mammalian, secreted WNT lipoglycoproteins that interact with a plethora of distinct receptors, such as the G protein-coupled receptors called Frizzleds (FZD1-10), LDL receptor-like proteins (LRP5/6), receptor tyrosine kinases (ROR1, 2, RYK and PTK7). In addition, WNT pathways are tightly regulated by many secreted and cell-intrinsic negative regulators, such as soluble FZD-related proteins (SFRPs), Dickkopfs (DKKs), WNT-inhibitory proteins, TIKI, RNF43 and more. Understanding the basic mechanism in terms of receptor-ligand interaction, receptor selectivity, signal initiation and desensitization remain poorly understood, even though substantial advances have been made the recent years. Due to the involvement of the WNT signaling system in human disease, it appears obvious to target diverse branches pharmacologically and therapeutically. However, given the complexity of the system and its importance for stem cell regulation and tissue maintenance, therapy comes with obvious risks for severe side effects. The field is addressing the challenge to identify suitable targets and selective compounds for therapy allowing disease-selective therapeutic effects and balancing unwanted side effects. This book summarizes the current understanding of the basic and applied pharmacology in the WNT signaling system and bridges disciplines such as pharmacology, physiology, neurosciences, oncology and drug development.
    Type of Medium: Online Resource
    Pages: VIII, 422 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030854997
    Series Statement: Handbook of Experimental Pharmacology, 269
    URL: https://doi.org/10.1007/978-3-030-85499-7
    DOI: 10.1007/978-3-030-85499-7
    DDC: 615
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  • 17
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    Online Resource
    The Art of Carbohydrate Analysis (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Chemistry, Organic. ; Food science. ; Biotechnology. ; Pharmacology. ; Organic Chemistry. ; Food Science. ; Biotechnology.
    Description / Table of Contents: Chapter 1 The World of Carbohydrates -- Chapter 2 Basic Knowledge of Glycobiology -- Chapter 3 Carbohydrates involved in Diseases -- Chapter 4 Detection of Carbohydrate by Colorimetric Methods -- Chapter 5. Analytical Techniques to Study Carbohydrates -- Chapter 6 Monosaccharide Composition Analysis -- Chapter 7 Carbohydrate Analysis of Glycoconjugates -- Chapter 8 Structural Characterization of Released Glycans -- Chapter 9 Analysis of Sialic Acids -- Chapter 10 Carbohydrate Microarray Technology -- Chapter 11 Analysis of Carbohydrates by Mass Spectrometry -- Chapter 12 Analysis of Carbohydrates by Nuclear Magnetic -- Chapter 13 Glycobioinformatics -- Chapter 14 Concluding Remarks. .
    Abstract: The growing importance of glycobiology and carbohydrate chemistry in modern biotechnology and the pharmaceutical industry makes accurate carbohydrate analysis indispensable. This book provides the principles and protocols of various fundamental carbohydrate analysis methods. Choice of method is entirely dependent upon the type of material being investigated (biological samples, food products, etc.), and the level of structural detail required, i.e. sugar content, compositional analysis, linkages between the sugar components, or the total chemical structure of a given molecule. Full structural characterization of carbohydrate chains requires significant time, resources, and skill in several methods of analysis; no single technique can address all glycan analysis needs. This book summarizes several existing analytical techniques (both chemical and physical) in an introductory volume designed for the non-expert researcher or novice scientist. While background in carbohydrate chemistry is assumed, all information necessary to understanding the described techniques is addressed in the text.
    Type of Medium: Online Resource
    Pages: XXV, 350 p. 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030777913
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-77791-3
    DOI: 10.1007/978-3-030-77791-3
    DDC: 615
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  • 18
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    Online Resource
    Polypharmacology : Principles and Methodologies (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Neuropharmacology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Neuropharmacology.
    Description / Table of Contents: PART I. Polypharmacology as a New Branch of Pharmacology: Concept and Principles -- Basics of Polypharmacology -- Polypharmacology in Clinical Applications: Multitarget Multidrug-combination (MTMD-C) -- Polypharmacology in Clinical Applications: Multitarget Multidrug-single-formulation (MTMD-SF) -- Polypharmacology in Clinical Applications: Multitarget Single-drug (MTSD) -- Polypharmacology in Drug Discovery: Designed Epigenetic MTSD and Small-molecule MTSD -- Anti-cancer Polypharmacology -- Cardiovascular Polypharmacology -- Neuronal Polypharmacology -- Pulmonary Polypharmacology -- Polypharmacology of Metabolic Disease -- Polypharmacology of Infectious Disease -- Polypharmacology of Inflammation -- Anti-psychotics Polypharmacology -- Anti-aging Polypharmacology -- Polypharmacology in Drug Repurposing -- Polypharmacology and Unintended Drug Promiscuity -- Polypharmacology Pharmacokinetics -- The Future of Polypharmacology -- PART II. Polypharmacology in New Drug Development: Strategies and Protocols -- Designed MTSD Discovery Process -- Designed MTSD Discovery Strategies -- Designed MTSD Discovery Technologies -- Designed MTSD Discovery Databases -- Designed MTSD Target Deconvolution.-Designed MTSD Target Validation -- Designed MTSD Lead Identification and Optimization -- Designed MTSD Discovery Protocols -- Natural Products in MTSD Discovery -- Polypharmacology Procedures for Drug Repurposing -- Polypharmacology Procedures for Drug Promiscuity Discovery.
    Abstract: There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on Polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology on Polypharmacology. This book aims to meet the needs of making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of Polypharmacology targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy. Rich in illustrations and tables to showcase readers for better understanding the concepts and technologies related to Polypharmacology; Provides comprehensive, systemic, holistic, and explicit explanations and discussion of the fundamental knowledge, background information, conceptual evolution, and updated methodology, as well as in-depth mechanisms behind the knowledge and methodology of Polypharmacology; Main emphasis on rationally designed Polypharmacology or “multi-target, single-drug (MTD)” pharmacology, which represents the major future direction of Polypharmacology and Pharmacology; Describes the clinical applications of Polypharmacology to various human diseases in the clinical and preclinical settings; Contains a wide collection of the state-of-the-art Polypharmacology technologies applicable to the designed MTD discovery and the step-by-step descriptions of drug discovery process applying Polypharmacology principles and methodologies.
    Type of Medium: Online Resource
    Pages: XXV, 856 p. 12 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031049989
    URL: https://doi.org/10.1007/978-3-031-04998-9
    DOI: 10.1007/978-3-031-04998-9
    DDC: 615
    Language: English
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  • 19
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    Online Resource
    Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    URL: https://doi.org/10.1007/978-981-16-4392-7
    DOI: 10.1007/978-981-16-4392-7
    DDC: 615
    Language: English
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  • 20
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    Online Resource
    Data Monitoring Committees (DMCs) : Past, Present, and Future (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Biometry. ; Toxicology. ; Pharmacology. ; Preclinical Research. ; Biomedical Research. ; Pharmaceutics. ; Biostatistics. ; Medical Toxicology.
    Description / Table of Contents: Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions.
    Abstract: This book provides an overview of Data Monitoring Committees - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotech/pharma and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity. This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to smoothly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the implications of it are so great. This book provides the following: Thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation; Includes practical and hands-on information on DMC implementation; Discusses a wide range of clinical trial – by phase and therapeutic area.
    Type of Medium: Online Resource
    Pages: XII, 111 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287602
    URL: https://doi.org/10.1007/978-3-031-28760-2
    DOI: 10.1007/978-3-031-28760-2
    DDC: 615
    Language: English
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  • 21
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    Macrophage Targeted Delivery Systems : Basic Concepts and Therapeutic Applications (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Cytology. ; Toxicology. ; Immunology. ; Pharmacology. ; Pharmaceutics. ; Cell Biology. ; Toxicology. ; Immunology.
    Description / Table of Contents: Part I Anatomy, Physiology and Pharmacology of Macrophages -- Introduction to Anatomy and Physiology of Macrophages from Drug Delivery Perspective -- Introduction to Pharmacology of Macrophages from Drug Delivery Perspective -- Mechanisms and Ways of Macrophage Delivery -- Macrophage Associated Disorders: Pathophysiology, Treatment Challenges and Possible Solutions -- Understanding Macrophage Associated Diseases and Applications of Nano Drug Delivery Systems -- Part II Polymeric Nanoparticles for Macrophage Targeting -- Targeting of Macrophages: Basic and therapeutic Role of Polymeric Nanoparticles -- Polymeric Nanoparticles Based Drug and Gene Delivery to Macrophages -- Surface Modification of Nanoparticles for Macrophage Targeting -- Part III Lipid Nanoparticles for Macrophage Targeting -- Liposomes as Delivery System for Macrophage Targeting -- Solid Lipid Nanoparticles Based Drug and Gene Delivery to Macrophages -- In vivo Fate of Colloidal Carriers Undergoing Macrophage Targeting -- Nanoparticle-based Theranostics for Macrophage-associated Diseases -- Part IV Targeting Macrophages for Treatment of Various Diseases -- Tumor Associated Macrophages as Therapeutic Target for Drug/immune Therapy of Cancer -- Macrophage Targeting for Therapy of Autoimmune Diseases -- Macrophage Targeting for Therapy of Cardiovascular Diseases (CVD) -- Macrophage targeting for therapy of intracellular infections -- Targeting Drugs and Nucleic Acids to Macrophages for Therapy of Inflammatory Diseases -- Macrophage Targeted Chemotherapy for Tuberculosis and other Respiratory Disease. -- Part V Specific Formulations and Clinical Trials on Macrophage Targeted Delivery -- Nano- and Microparticles Based Dry Powder Inhalers for Pulmonary Macrophage Drug Delivery -- Recent Trends in Clinical Studies on Macrophage Targeted Delivery -- Future Directions and Challenges in Macrophage Targeting. .
    Abstract: The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting. Macrophages have gained substantial attention as therapeutic targets for drug delivery considering their major role in health and regulation of diseases. Macrophage-targeted therapeutics have now added significant value to the lives and quality of life of patients, without undue adverse effects in multiple disease settings. We anticipate examining and integrating the role of macrophages in the instigation and advancement of various diseases. The major focus of the book is on recent advancements in various targeting strategies using delivery systems or nanocarriers followed by application of these nanocarriers for the treatment of macrophage associated disorders. Macrophage Targeted Delivery Systems is primarily targeted to Pharmaceutical Industry & Academia, Medical & Pharmaceutical Professionals, Undergraduate & Post graduate students and Research Scholars, Ph.D, post docs working in the field of medical and pharmaceutical sciences.
    Type of Medium: Online Resource
    Pages: XVIII, 556 p. 76 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030841645
    URL: https://doi.org/10.1007/978-3-030-84164-5
    DOI: 10.1007/978-3-030-84164-5
    DDC: 615
    Language: English
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  • 22
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    Online Resource
    Synbiotics for the Management of Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cancer. ; Cancer Treatment. ; Pharmacology. ; Cancers. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Effect of anticancer treatment approches on gut microbiota -- Chapter 3_Synbiotic: A promising approach for the treatment of cancer -- Chapter 4_Correlation between ROS and Synbiotics for effective treatment of cancer -- Chapter 5_Influence of synbiotics on inflammation and immune microenvironment for the treatment of cancer -- Chapter 6_Synbiotics in colorectal cancer -- Chapter 7_Synbiotics in cervical cancer -- Chapter 8_Synbiotics in prostate cancer -- Chapter 9_Synbiotics in gastric cancer -- Chapter 10_Synbiotics in lung cancer -- Chapter 11_Synbiotics in small cell pancretatic cancer -- Chapter 12_Synbiotics in breast cancer -- Chapter 13_Synbiotics in hepatocellular carcinoma -- Chapter 14_Synbiotics in ovarian cancer -- Chapter 15_Regulatory issues of synbiotics in cancer.
    Abstract: This book illustrates the significance of probiotics and prebiotics for the management of various types of cancers. The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment. It also describes the regulatory issues about synbiotics in the management of cancer. This book is an essential resource for scientists working in the field of cancer, pharmaceutical & clinical sciences, and cancer clinicians. This book is also very useful for undergraduate and postgraduate students of Pharmacy and Biotechnology and medical researchers, mainly working in microbiology, immunology, and cancer biology.
    Type of Medium: Online Resource
    Pages: XVII, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811975509
    URL: https://doi.org/10.1007/978-981-19-7550-9
    DOI: 10.1007/978-981-19-7550-9
    DDC: 615
    Language: English
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  • 23
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    Online Resource
    Recent Advances in Pharmaceutical Innovation and Research (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    URL: https://doi.org/10.1007/978-981-99-2302-1
    DOI: 10.1007/978-981-99-2302-1
    DDC: 615
    Language: English
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  • 24
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    Online Resource
    Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Description / Table of Contents: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Abstract: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Type of Medium: Online Resource
    Pages: XVII, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819969173
    URL: https://doi.org/10.1007/978-981-99-6917-3
    DOI: 10.1007/978-981-99-6917-3
    DDC: 615
    Language: English
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  • 25
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    Online Resource
    Pharmacology of Immunotherapeutic Drugs (2020)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Immunology. ; Pharmacology. ; Immunology.
    Description / Table of Contents: Preface Chapter 1: Overview of the Immune System and its Pharmacological Targets -- Chapter 2: Modulation of the Innate Immune System -- Chapter 3: Modulation of the Adaptive Immune System -- Chapter 4: Respiratory Disorders of the Immune System and their Pharmacological Treatment -- Chapter 5: Inflammation of the Skin and its therapeutic topics -- Chapter 6: Inflammatory Diseases of the Gastrointestinal Tract and Pharmacological Treatments -- Chapter 7: Mechanisms of Autoimmunity and Pharmacologic Treatments -- Chapter 8: Transplantation: Immunologic Principles and Pharmacologic Agents -- Chapter 9: Immunopathogenesis, Immunization, and Treatment of Infectious Diseases -- Chapter 10: Cancer Immunotherapy.
    Abstract: Medicine has entered a golden age in which therapeutic agents are becoming widely available due to advances in basic science and technology. As such, many drugs have been developed that target inflammatory processes and/or the immune system. This book is intended for health professionals examining the modulation of inflammation by immunotherapeutic drugs. The immune system fills the primordial role of host defense and resistance to infections with pathogenic microorganisms. Several hematopoietic-derived cells constituting the innate and adaptive immune systems cooperate to provide barriers for microbial colonization and/or promote pathogen destruction within the host. Conversely, many immune cells are also involved in the pathogenesis and propagation of chronic inflammatory diseases. The beginning of this book details various components of the immune system including the cell types, lymphoid tissues, soluble cytokines and surface molecules that are essential for host defense. Breakdowns in immune tolerance, or dysregulated immune responses to antigens derived from self tissues or innocuous sources, can lead to the development of autoimmunity or chronic inflammatory diseases. Pathophysiologic roles for the immune system are detailed in corresponding chapters on autoimmunity, epithelial surfaces (lungs, skin, intestine), and transplantation, with special emphasis placed on immunotherapeutic drug targets. The last section of the book focuses on treatments that stimulate our immune system to specifically target and fight infectious diseases and cancer. In each chapter, the medications used to treat various diseases/conditions in terms of their mechanism of action and other pharmacologic properties are discussed in detail. Chapters begin with a table showing drug names and classifications. The importance of basic science and clinical trials cannot be understated in the context of drug development. As such, the discovery of certain medications that had a lasting impact in medicine and pharmacy are highlighted in chapter subsections named “Bench to Bedside.” Several clinical applications of immunotherapeutic drugs are described within end-of -chapter case studies including practice questions. The Pharmacology of Immunotherapeutic Drugs is a reference for immunologists and clinicians (medical doctors, pharmacists, nurses) examining the modulation of inflammatory processes by a variety of medications targeting the cells and mediators of our immune system.
    Type of Medium: Online Resource
    Pages: XIX, 399 p. 118 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030199227
    URL: https://doi.org/10.1007/978-3-030-19922-7
    DOI: 10.1007/978-3-030-19922-7
    DDC: 615
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  • 26
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    Online Resource
    Biomedical Applications and Toxicity of Nanomaterials (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Nanomedicine. ; Pharmacology. ; Nanobiotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Chapter 1. Macroporous cryogel-based systems for water treatment applications and Safety: nanocomposite-based cryogels and bacteria-based bioreactors -- Chapter 2. One dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications -- Chapter 3. Prospects of Safe use of Nanomaterials in Biomedicalapplications -- Chapter 4. Hyaluronic acid-based nanotechnologies for delivery and treatment -- Chapter 5. Theranostics nanomaterials for safe cancer treatment -- Chapter 6. Cardiovascular safety assessment of new chemical entities: current perspective and emerging technologies -- Chapter 7. Toxicology of pharmaceutical products during drug development -- Chapter 8. Safety and Risk assessment of food items -- Chapter 9. Non toxic Natural products as regulators of tumour suppressor gene function -- Chapter 10. Advancements in the safety of Plant medicine: Back to nature -- Chapter 11. Chemicals and their interaction in the aquaculture system -- Chapter 12. Zebrafish as a biomedical model to define developmental origins of chemical toxicity -- Chapter 13. Green synthesis of non toxic nanoparticles -- Chapter 14. Synthesis, characterisation and safety of titanium oxide nanoparticles -- Chapter 15. Characterisation of non toxic nanomaterials for biological applications -- Chapter 16. Toxicity assessment of nanoparticle -- Chapter 17. Safety of nanoparticles: emphasis on antimicrobial properties -- Chapter 18. Quantum dots for imaging and its safety -- Chapter 19. Genotoxicity evaluation of nanosized materia -- Chapter 20. Scaffoldmaterials and toxicity -- Chapter 21 Biological Safety and Cellular interactions of nanoparticles -- Chapter 22. Role of artificial intelligence in the toxicity prediction of drugs -- Chapter 23. Chemicals and rodent models for the safety study of alzheimer’s disease -- Chapter 24. Mitochondria-targeted liposomal delivery in Parkinson's disease: safety concerns -- Chapter 25. Routes of Nano-drug Administration and Nano-based drug delivery system and toxicity -- Chapter 26. Green Synthesised silver nanoparticles phytotoxicity and applications in agriculture: An overview -- Chapter 27 status of safety concerns of microplastic detection strategies -- Chapter 28. Impact of insecticides on man and environment.
    Abstract: This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
    Type of Medium: Online Resource
    Pages: XVIII, 768 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978340
    URL: https://doi.org/10.1007/978-981-19-7834-0
    DOI: 10.1007/978-981-19-7834-0
    DDC: 615
    Language: English
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  • 27
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    Online Resource
    Pharmacology of Drug Stereoisomers (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Medicinal chemistry. ; Pharmaceutical chemistry. ; Biotechnology. ; Biochemical engineering. ; Pharmacology. ; Medicinal Chemistry. ; Pharmaceutics. ; Biotechnology. ; Bioprocess Engineering.
    Description / Table of Contents: Preface -- General principles of chirality -- Quantitative methods of analysing chirality drugs - Chirality and pharmacokinetics -- Drugs regulating the function of peripheral nervous system -- In silico search for chiral drug compounds.
    Abstract: The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.
    Type of Medium: Online Resource
    Pages: XI, 207 p. 174 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811923203
    Series Statement: Progress in Drug Research, 76
    URL: https://doi.org/10.1007/978-981-19-2320-3
    DOI: 10.1007/978-981-19-2320-3
    DDC: 615
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  • 28
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    Online Resource
    Rabies and Rabies Vaccines (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Virology. ; Immunology. ; Pharmacology. ; Virology. ; Immunology.
    Description / Table of Contents: Rabies Life Cycle, Transmission and Pathogenesis -- History of Rabies and Rabies Vaccines -- Rabies vaccines for wildlife -- Human Rabies Vaccines -- Rabies vaccines, prophylactic, Peru -- Rabies Prevention in Asia: Institutionalizing Implementation Capacities -- Passive Immunity in Rabies Prophylaxis -- Rabies Little Virus Against Powerful Innate Immunity -- Novel Rabies Vaccines -- Assessing the potency of inactivated veterinary vaccines and oral live vaccines against rabies -- WHO Perspective on Rabies.
    Abstract: This book reviews the recent advances in rabies research and rabies vaccine development. The reader is introduced to biology and pathology of the virus, causing agents and the history of rabies vaccination. The book presents regional rabies prophylaxis programs and discusses vaccination strategies for wildlife and humans. Further, innate immune response as well as antibody response to rabies are examined. All chapters are written by renowned experts in rabies research, some of them part of the WHO Collaboration Centre for Rabies Surveillance and Research. The book targets researchers and health professionals working in Virology, Veterinary Medicine and Biomedicine. .
    Type of Medium: Online Resource
    Pages: VII, 205 p. 15 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030210847
    URL: https://doi.org/10.1007/978-3-030-21084-7
    DOI: 10.1007/978-3-030-21084-7
    DDC: 615
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  • 29
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    Online Resource
    Principles of Forensic Toxicology (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Forensic sciences. ; Medical jurisprudence. ; Pharmacology. ; Forensic Science. ; Forensic Medicine.
    Description / Table of Contents: Part 1: Introduction -- Post Mortem Forensic Toxicology -- Human Performance Toxicology -- Drug-Facilitated Sexual Assault -- Forensic Drug Testing -- Performance enhancing Drug Testing -- Drug Testing in Pain Management -- Pharmacokinetics and Pharmacodynamics -- Part II. Specimen Preparation -- Spectrophotometry -- Chromatography -- Derivatization -- Immunoassy -- Mass Spectrometry -- Quantitation -- Method Validation -- Measurement Uncertainty and Traceability -- Statistics in Forensic Toxicology -- Part III Analytes -- Alcohol -- Benzodiazapines -- Gammahydroxybutyric acid,- Miscellaneous Central Nervous System Depressants -- Opioids -- Cocanie -- Cannabis -- Amphetamines-Sympathomimetic Amines,- Hallucinogens and Psychedelics -- Antidepressants and Neuroleptics -- Miscellaneous Therapeutic Drugs -- Carbon Monoxide/Cyanide -- Inhalants -- Metals -- Part III Special Topics -- Stability of Drugs of Abuse in Biological Systems -- Postmortem Redistribution of Drugs -- Postmortem Clinical Testing -- Pharmacogenomics -- Hair Drug Testing -- Oral Fluid Testing -- Meconium Drug Testing -- Drugs in Embalmed Tissues.
    Abstract: The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner’s offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.
    Type of Medium: Online Resource
    Pages: XIII, 691 p. 188 illus., 23 illus. in color. , online resource.
    Edition: 5th ed. 2020.
    ISBN: 9783030429171
    URL: https://doi.org/10.1007/978-3-030-42917-1
    DOI: 10.1007/978-3-030-42917-1
    DDC: 615
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  • 30
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    Online Resource
    Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Pharmacology. ; Toxicology. ; Pharmaceutics.
    Description / Table of Contents: Therapeutic and toxic concentration of drugs in biological matrices -- Analytical techniques for therapeutic drug monitoring and clinical toxicology -- Plasma therapeutic drug monitoring and clinical toxicology -- Dried blood spots in therapeutic drug monitoring and toxicology -- The role of artificial intelligence in therapeutic drug monitoring and clinical toxicity -- Therapeutic drug monitoring and optimal pharmacotherapy with medicines of narrow therapeutic index -- Therapeutic drug monitoring (TDM) and toxicological studies in alternative biological matrices -- Analyzing data from therapeutic drug monitoring, pharmacokinetics, and clinical toxicology studies -- Reducing toxicity in critically ill patients by using therapeutic drug monitoring -- Quality assurance of samples for therapeutic drug monitoring and clinical toxicology -- Therapeutic drug monitoring and toxicology of anticancer drugs -- Therapeutic drug monitoring and toxicology of immunosuppressant -- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites -- Recent advances in nanosensors for Therapeutic Drug Monitoring (TDM) -- Organ toxicity by immunosuppressive drugs in solid organ transplantation -- Artificial intelligence-based techniques to assess drug toxicity in drug induced liver injury (DILI) disease -- Drug dose and therapy individualization -- Models for drug individualization: patient to population level -- Toxicity evaluation of nanomedicine -- Biochemical indices of drug toxicity -- Therapeutic drug monitoring and clinical toxicology: challenges and future directions.
    Abstract: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges .
    Type of Medium: Online Resource
    Pages: XVIII, 381 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031123986
    URL: https://doi.org/10.1007/978-3-031-12398-6
    DOI: 10.1007/978-3-031-12398-6
    DDC: 615
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  • 31
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    From PharmD to Industry : A Fellowship Guide (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Career education. ; Pharmacology. ; Pharmacy. ; Career Skills.
    Description / Table of Contents: Fellowship 101 -- The First Professional Year (P1) -- The Second Professional Year (P2) -- The Third Professional Year (P3) -- The Fourth Professional Year (P4) -- Midyear Applications, Interviews, and Receptions -- Transitioning from Student to Fellow -- Navigating the Virtual Landscape.
    Abstract: For many Doctor of Pharmacy (PharmD) candidates, post-graduate training is a highly prestigious and sought after experience that can further one’s pre-existing education. Some of these post-graduate training opportunities include but are not limited to pharmacy residencies, pharmaceutical industry fellowships, and PhD/Masters programs. There is a large gap in the current Doctor of Pharmacy curriculum about pharmaceutical industry fellowship programs and potential pharmaceutical industry opportunities. Through the eyes of current industry fellows and professionals, this book serves as a resource to learn more about fellowship opportunities and their respective application processes. In addition, this manual aims to provide a clear and concise roadmap to achieving a career in industry through a fellowship program. Whether you are a current student pharmacist, post-graduate pharmacy trainee (pharmacy resident), or industry professional, this manual addresses the current landscape of industry fellowship programs, an overview of industry opportunities, and a glimpse into what being a fellow entails. Readers of this book can expect to gain: An overview of pharmaceutical industry fellowship programs and opportunities Helpful advice and insight from current fellows and industry professionals A streamlined pathway to navigating the fellowship application process An understanding of the journey from being a student, to achieving a fellowship, to becoming an industry professional This book bridges the gap in education surrounding pharmaceutical industry fellowships and pharmacy careers in industry and increases access to first-hand information and real-world perspectives of current professionals to provide a firm foundation for those interested in pursuing a career in industry or learning more about fellowship programs.
    Type of Medium: Online Resource
    Pages: XIX, 92 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031357879
    Series Statement: SpringerBriefs in Pharmaceutical Science & Drug Development,
    URL: https://doi.org/10.1007/978-3-031-35787-9
    DOI: 10.1007/978-3-031-35787-9
    DDC: 615
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  • 32
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    Online Resource
    Contract Research and Development Organizations-Their History, Selection, and Utilization (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Pharmacology. ; Pharmacy.
    Description / Table of Contents: Introduction -- History of CROs: Including CRO Snapshots and a CRO Genealogy Chart -- The Pharmaceutical Development Process & Testing Requirements -- The Medical Device Development Process & Testing Requirements -- Functions and Types of CROs -- Labs in China and India -- Selection of CROs -- Study Directors and PIs -- Nuts and Bolts of Study Performance SCG/CBS -- Electronic Reporting Requirements (SEND & eCTD) -- Study and Project Monitoring -- Contracting, Pricing, and Cost of Works Performed by CROs -- Consultants and their Role -- Building Relationships: Maximizing your return on Expectations with a CRO -- Common Problems and their Solutions -- Appendices: A Toxicology Labs B Medical Device Labs C Phase I Labs D Analytical Labs E GMP Contract Facilities F Formulation G Dosage Forms H Clinical Testing I Regulatory Services J Forms and Checklists -- K Specialized Services -- L Consultants Known to be In-Practice -- Index. .
    Abstract: This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics: · The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went. · Study directors and principal investigators. · The nuts and bolts of study performance. · Electronic reporting requirements – SEND and eCTD (required for NDA, BLA, ANDA, and IND submissions). · Consultants and their roles. · An expanded examination of common problems and their solutions. This book boasts complete directories to the global universe of operating labs – where they are, how to contact them, and what they do (including special capabilities). Additionally, checklists for qualifying labs and manufacturing facilities – and for auditing studies and projects at such facilities – are included. It is directed at those in industry (specifically directed at those working for companies using CRO services) but will also be of interest to scientists or administrators working in research organizations themselves. In this case, the contents of this new work are essential to the target reader because the work, regulations, and actors (CROs) have evolved and changed at a rapid pace in the 10 years since the earlier volume that the author published. Likewise, the companies using these services have come to all be almost completely dependent on outsourcing. The earlier texts remain the only source of their kind (paper or electronic) on the field and the only noncommercial guide to the global industry and this volume provides a complete update.
    Type of Medium: Online Resource
    Pages: XIII, 519 p. 19 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030430733
    URL: https://doi.org/10.1007/978-3-030-43073-3
    DOI: 10.1007/978-3-030-43073-3
    DDC: 615
    Language: English
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    Toll-like Receptors in Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Immunology. ; Inflammation. ; Pharmacology. ; Immunology. ; Inflammation.
    Description / Table of Contents: Intracellular TLRs (TLR3, TLR7, and TRL9) in host defense or TLRs in mast cells -- Toll-like receptors as drug targets in the intestinal epithelium -- Innate immune memory-priming, tolerance and exhaustion-in health and disease -- TLRs in brain immunity -- TLRs in cerebrovascular diseases -- TLRs in stem cells or progenitor cells -- TLRs in adaptive immunity -- Overview on TLRs in immunity -- TLR10 and its role in immunity.
    Abstract: The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial lipopolysaccharide (LPS). This discovery revolutionized the field of innate immunity and filled the long-standing gap in the pathogen recognition by the immune system. Now, it is well established that humans have 10 (TLR1-TLR10) and mice have 12 (TLR1-TLR13) functional TLRs, excluding TLR10 that is present as a defective pseudogene. TLRs are present as both membrane-bound extracellular (TLR1, TLR2, TLR4, TLR5, TLR6, and TLR10) and intracellular (TLR3, TLR7, TLR8, and TLR9) PRRs in humans, which identify different pathogen or microbe-associated molecular patterns (PAMPs or MAMPs) and death or damage-associated molecular patterns (DAMPs) released by the host cells. A lot of development in the TLR biology has occurred in last 24 years since there first discovery in humans. The book is intended to describe their role in the host defence, human reproduction, non-infectious sterile inflammatory conditions, including brain immunity and cerebrovascular diseases, signaling mechanisms, adaptive immunity, and their targeting for drug development.
    Type of Medium: Online Resource
    Pages: VIII, 314 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065125
    Series Statement: Handbook of Experimental Pharmacology, 276
    URL: https://doi.org/10.1007/978-3-031-06512-5
    DOI: 10.1007/978-3-031-06512-5
    DDC: 615
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    Prebiotics, Probiotics and Nutraceuticals (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Abstract: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689901
    URL: https://doi.org/10.1007/978-981-16-8990-1
    DOI: 10.1007/978-981-16-8990-1
    DDC: 615
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    Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Surgery. ; Dentistry. ; Veterinary medicine. ; Neurology . ; Orthopedic surgery. ; Pharmacology. ; Surgery. ; Dentistry. ; Veterinary Science. ; Neurology. ; Surgical Orthopedics.
    Description / Table of Contents: 1. History of development of botulinum toxin therapy in medical and surgical fields -- 2. Molecular structure and mechanisms of action of botulinum toxins as it pertains to clinical symptoms -- 3. Types of toxins in commercial use, their similarities and differences -- 4. A review of current Botulinum toxin treatment indications in medical field. - 5. Mechanisms of Analgesic effects of botulinum neurotoxins -- 6. Botulinum toxin treatment in Head and neck surgery -- 7. Botulinum toxin treatment of thoracic and abdominal surgery -- 8. Botulinum Toxin A in Abdominal Wall Reconstruction -- 9. Use of Botulinum toxin A in post-mastectomy breast reconstruction -- 10. Botulinum Toxins for Treatment of Pain in Orthopedic Disorders -- 11. Botulinum toxin for pediatric patients, Who? For what? When? -- 12. Botulinum Toxin Treatment in Plastic Surgery -- 13. Botulinum Toxin Treatment in Ophthalmology and Ophthalmic surgery -- 14. Botulinum Toxin Treatment in Gastrointestinal Disorders -- 15. Botulinum Toxin Treatment in Urological Disorders -- 16. Botulinum Toxin Treatment in Dentistry -- 17. Botulinum toxin treatment in Veterinary Medicine - Clinical implications -- 18. Future Perspectives of Botulinum Toxin Application In Dentistry.
    Abstract: All books on the market which have been written on the subject of botulinum toxin therapy focus on treatment of hyperactive movement disorders, autonomic dysfunction (bladder, sweat and salivary glands) and some pain indications (migraine). Reference to pre-or post -surgical indications are brief and often out-dated. No book has information on dentistry or veterinary medicine. This book provides up-to-date information on botulinum toxin therapy in surgical fields. It is also the only book in the market that provides information on botulinum toxin therapy in dentistry and veterinary medicine and furnishes the latest information. Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine appeals to many disciplines including surgery, dentistry and veterinary medicines well as appealing to neurologists and internists.
    Type of Medium: Online Resource
    Pages: VIII, 398 p. 70 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506919
    URL: https://doi.org/10.1007/978-3-030-50691-9
    DOI: 10.1007/978-3-030-50691-9
    DDC: 615
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    Metabolomics and Its Impact on Health and Diseases (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Biochemical markers. ; Cytology. ; Analytical biochemistry. ; Pharmacology. ; Biomarkers. ; Cell Biology. ; Analytical Biochemistry.
    Description / Table of Contents: Preface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR – Avoiding the ‘Black-Box’ -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.
    Abstract: This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
    Type of Medium: Online Resource
    Pages: VIII, 384 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031268595
    Series Statement: Handbook of Experimental Pharmacology, 277
    URL: https://doi.org/10.1007/978-3-031-26859-5
    DOI: 10.1007/978-3-031-26859-5
    DDC: 615
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    Structure and Health Effects of Natural Products on Diabetes Mellitus (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Botanical chemistry. ; Bioorganic chemistry. ; Pharmacology. ; Plant Biochemistry. ; Bioorganic Chemistry.
    Description / Table of Contents: Chapter 1. Introduction of diabetes melitus and future prospects of natural products on diabetes melitus -- Chapter 2. Anoverview of hypoglycemic modern drugs -- Chapter 3. An overview of hypoglycemic biological drugs -- Chapter 4. An overview of hypoglycemic traditionaldrugs -- Chapter 5. Glycosides from natural sources in the treatment of diabetes mellitus -- Chapter 6. Isolation and Structure Elucidation of Hypoglycemic Compounds -- Chapter 7. Structural Characterization and Health Effects of Polysaccharides from Momordica charantia on Diabetes Mellitus -- Chapter 8. Effects of polysaccharides on reducing blood glucose based on gut microbiota alteration -- Chapter 9. An Overview of Polysaccharides and the influencefactors of Hypoglycemic Activity -- Chapter 10. Plant Secondary Metabolites with α-Glucosidase Inhibitory Activity. - Chapter 11. Rhinacanthin-C and Its Potential to Control Diabetes Mellitus -- Chapter 12. Regeneration of beta cells by inhibition of pro-apoptotic proteins through phytocompound in STZ induced diabetic albino wistar rats-invivo and insilico approach. - Chapter 13. Nitrogenous Compounds from Plant Origin in Management of -- Chapter 14. Plant Alkaloids with Antidiabetic Potential -- Chapter 15. The role of Alkaloids in the Management of Diabetes Mellitus -- Chapter 16. Traditional Indian Herbs for the Management of Diabetes Mellitus and their Herb-Drug Interaction Potentials: An Evidence-Based Review -- Chapter 17. Role of Micronutrients and Trace elements in Diabetes mellitus: A Review.
    Abstract: The purpose of this book is to introduce the classified chemical components of hypoglycemic compounds in natural products, summarize the recent research progress of natural products with hypoglycemic activity in the past 20 years, and provide the original analysis and development opinions of relevant scholars. Hypoglycemic compounds are to target diabetes mellitus, an important public health problem, one of four priority noncommunicable diseases (NCDs) targeted for action by world leaders. Diabetes mellitus is a common endocrine and metabolic disease, which not only causes physiological damage to patients' kidneys, cardiovascular and cerebrovascular vessels, peripheral blood vessels, nerves and eyes, but also causes mental and psychological pressure to patients. Due to the evidence that traditional medicine and natural herbal formula have advantages in treating diabetes, natural products with hypoglycemic activity have been studied extensively in recent years and have been accepted by many scholars all over the world. This book focuses on the progress on the study of the structure, hypoglycemic activities, structure-activity relationships and mechanism of a wide range of polysaccharides, flavonoids, saponins, alkaloids, terpenoids, polyphenols and other constituents. It will help students and researchers to understand current approaches and progress in the treatment of diabetes with natural products, which may also be beneficial to develop new hypoglycemic drugs.
    Type of Medium: Online Resource
    Pages: VIII, 307 p. 85 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811587917
    URL: https://doi.org/10.1007/978-981-15-8791-7
    DOI: 10.1007/978-981-15-8791-7
    DDC: 615
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    Pharmacology of Immunosuppression (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Human physiology. ; Immunology. ; Surgery. ; Pharmacology. ; Human Physiology. ; Immunology. ; Surgery.
    Description / Table of Contents: Review of the Pathophysiology of the Alloimmune response -- A Comprehensive Review of Calcineurin Inhibitors Used for Immunosuppression in Cardiac Transplantation -- Anti-proliferative Agents -- Mechanistic Target of Rapamycin (mTOR) Inhibitors -- Corticosteroids -- Induction therapy and antibodies -- Immunosuppression and Heart Transplantation -- Immunosuppression and Lung Transplantation -- Immunosuppression and renal transplant recipients -- Immunosuppression in Rheumatologic and Auto-immune Disease -- Immunosuppression in Bone Marrow Transplantation -- Immunosuppression in Multiple Sclerosis and Other Neurologic Disorders -- Novel immunosuppressive agents for the treatment of organ transplants -- Adverse Effects of Immunosuppression: Infections -- Malignancy: An Adverse Effect of Immunosuppression -- Adverse Effects of Immunosuppression:Nephrotoxicity, Hypertension and Metabolic Disease.
    Abstract: The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bone marrow transplantation and autoimmune diseases and inflammatory diseases. This book is a critical review of these topics and a vital resource.
    Type of Medium: Online Resource
    Pages: VIII, 348 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031051180
    Series Statement: Handbook of Experimental Pharmacology, 272
    URL: https://doi.org/10.1007/978-3-031-05118-0
    DOI: 10.1007/978-3-031-05118-0
    DDC: 615
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    Evidence Based Validation of Traditional Medicines : A comprehensive Approach (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medical microbiology. ; Medicinal chemistry. ; Pharmacovigilance. ; Pharmacology. ; Medical Microbiology. ; Medicinal Chemistry. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1. Global Approach for Drug Discovery and Development from Indian Traditional Medicine -- Chapter 2. Bioactive Natural Leads TargetingCancer Cell Metabolism -- Chapter 3. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products -- Chapter 4. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects -- Chapter 5. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin -- Chapter 6. Role of Phytomolecules on the Basic Biology of Aging -- Chapter 7. Role of phytomedicine in alleviating oxidative stress mediated vascular complications in diabetes -- Chapter 8. Plant Based -Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer's Disorder -- Chapter 9. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis - Play a Pivotal Role in Combating Human Pathogens. Chapter 10. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development -- Chapter 11. Cell-based Assays in Natural Product-based Drug Discovery -- Chapter 12. Allelochemicals: An Emerging Tool for Weed Management -- Chapter 13. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing -- Chapter 14. Importance of Chromatography Techniques in Phytomedicine Research -- Chapter 15. Reverse Pharmacology – A Tool for Drug Discovery From Traditional Medicine -- Chapter 16. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations -- Chapter 17. HPTLC Fingerprinting analysis of Phytoconstituents from Indigenous Medicinal Plants -- Chapter 18. Climate Change,Geographical Location and Other Allied Triggering Factors Modulate the Standardization and Characterization of Traditional Medicinal Plants: AChallenges and Prospect for Phyto-Drug Development -- Chapter 19. Molecular Docking Studies of Plant-Derived Bioactive Compounds: A Comprehensive in silico Standardization Approach -- Chapter 20. Standardization and Quality Evaluation of Botanicals with Special Reference to Marker Components -- Chapter 21. Analytical Standardization of Haridra Formulation by UV-VIS Spectrophotometry and RP-HPLC -- Chapter 22. Ethnobotanical survey: the foundation to evidence based validation of medicinal plants -- Chapter 23. Phytotherapeutics: The Rising Role of Drug Transporters in Herb-Drug Interactions with Botanical Supplements -- Chapter 24. An Insight into Herb Interactions: Clinical Evidence Based Overview -- Chapter 25. Pharmacovigilance of Herbal Medicines: An Overview -- Chapter 26. Herbal Drugs: Efficacy, Toxicity and Safety Issues -- Chapter 27. Herbal Drug Patenting -- Chapter 28. Safety and Regulatory Issues on Traditional Medicine Entrusted Drug Discovery -- Chapter 29. Pharmacovigilance of Herbal Medicine: An Evolving Discipline -- Chapter 30. Toxicity Studies Related to Medicinal Plants -- Chapter 31. Herb-Drug Interactions -- Chapter 32. Plant Based Traditional Herbal Contraceptive Use in India: Safety and Regulatory Issues -- Chapter 33. Traditional Medicine Stability and Pharmacokinetic Issue -- Chapter 34. Pharmacovigilance: Methods in developing the safety and acceptability of traditional medicines -- Chapter 35. Zoopharmacognosy (Plant-Animal Interaction) -- Chapter 36. Significance of Stability and Pharmacokinetic issues in Traditional Medicine -- Chapter 37. Pharmaceutical Formulations Development Based on the Polymers Obtained from Edible Plants: An Excellent Approach for the Betterment in Health Care Services -- Chapter 38. Evaluation of bioactivity of green nanoparticles synthesized from traditionally used medicinal plants: a review -- Chapter 39. Physicochemical, Micromeritics, Biomedical and Pharmaceutical Applications of Assam Bora Rice Starch -- Chapter 40. Natural Excipients in Pharmaceutical Formulations -- Chapter 41. A Wonder Plant Withania: Pharmacological and Chemical Perspectives -- Chapter 42. Immunomodulators and Phyto Drugs -- Chapter 43. Combined Effects of Plant Extracts on Ovarian Cell Functioning -- Chapter 44. Pterocarpussantalinus: A Wonder Gift of Nature -- Chapter 45. Phytochemicals And Investigations On Traditionally Used Medicinal Mushrooms -- Chapter 46. A Review On Investigational Studies Of Marine Macroalgae Spogomorpha Indica L -- Chapter 47. Validation of Traditional Claim of Oxalis debilis Kunth., An Ethnomedicinal Plant from North-eastern Region of India -- Chapter 48. Traditional Herbal Medicine Practiced in Plateau-Fringe and Rarh Districts of West Bengal, India -- Chapter 49. Pharmacology and Mechanisms of Natural Medicine in Treatment of Type 2 Diabetes Mellitus -- Chapter 50. Indian Traditional Herbs and Alzheimer’s Disease: Integrating Ethnobotany and Phytotherapy. .
    Abstract: The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine. .
    Type of Medium: Online Resource
    Pages: XII, 1151 p. 378 illus., 125 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581274
    URL: https://doi.org/10.1007/978-981-15-8127-4
    DOI: 10.1007/978-981-15-8127-4
    DDC: 615
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    From Obesity to Diabetes (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Metabolism Disorders. ; Pharmacology. ; Metabolic Disease.
    Description / Table of Contents: Part I Obesity. Epidemiology of Obesity -- The Circadian Clock and Obesity -- Nutrition and Microbiome -- From Obesity to Diabetes: The Role of the Adipose Organ -- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy -- The Enteroendocrine System in Obesity -- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches -- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction -- Obesity, Senescence, and Senolytics -- Obesity and Obstructive Sleep Apnea -- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance -- Islet Inflammation and β Cell Dysfunction in Type 2 Diabetes -- NAFLD and NASH: The Metabolically Diseased Liver -- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities -- Diabetic Peripheral Neuropathy -- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies -- Physical Activity, Obesity and Weight Loss Maintenance -- Bariatric/Metabolic Surgery -- Drugs for Treating Obesity -- Novel Drugs for Diabetes Therapy -- Novel Approaches to Restore Pancreatic Beta-Cell Mass and Function -- Precision Medicine and Obesity -- Targeting the Enteroendocrine System for Treatment of Obesity.
    Abstract: Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
    Type of Medium: Online Resource
    Pages: VIII, 513 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030999957
    Series Statement: Handbook of Experimental Pharmacology, 274
    URL: https://doi.org/10.1007/978-3-030-99995-7
    DOI: 10.1007/978-3-030-99995-7
    DDC: 615
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    Immunity Boosting Medicinal Plants of the Western Himalayas (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Botany. ; Ethnology. ; Pharmacology. ; Natural Products. ; Plant Science. ; Ethnography.
    Description / Table of Contents: 1. Introduction to Western Himalayas -- 2. Achillea millefolium L., Common Yarrow -- 3. Arisaema jacquemontii Blume, Jacquemont's Cobra Lily -- 4. Species of Arnebia genus found in the western Himalayas -- 5. Species of the Berberis genus found in the western Himalayas -- 6. Dactylorhiza hatagirea (D.Don) Soo – Himalayan Marsh Orchid -- 7. Fritillaria roylei Hook.f.: Himalayan Fritillary -- 8. Gentiana kurroo Royle: Himalayan Gentian -- 9. Habenaria intermedia D.Don and Habenaria edgeworthii Hook., f. ex Collett.: The Western Himalayan medicinal Plants -- 10. Humulus lupulus L.: Beer plant -- 11. Inula racemosa Hook. f. – Puskarmool: Its ethnobotanical uses, phytochemicals and pharmacological activities -- 12. Juniperus recurva Buch.-Ham. ex D.Don and Juniperus squamata D. Don: Himalayan Juniper -- 13. Lancea tibetica Hook.f. & Thomson: Ethnobotany, phytochemistry and pharmacology -- 14. Malaxis muscifera (Lindley) O. Kuntze. and Malaxis acuminata D. Don.: Jeevak -- 15. Picrorhiza kurroa Royle ex Benth.: Kutki -- 16. Species of the genus Polygonatum found in the Western Himalayas -- 17. Species of the genus Rhodiola found in the Western Himalayas -- 18. Saussurea lappa C.B. Clarke: Kushta/Kut -- 19. Saussurea lappa C.B. Clarke: Kushta/Kut -- 20. Species of the genus Selinum found in the western Himalayas -- 21. Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta -- 22. Taxus wallichiana Zucc.: The Himalayan yew -- 23. Tribulus terrestris L.: Gokshur /Gokharu -- 24. Species the Genus Viola found in Western Himalayas.
    Abstract: This book presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology. The book offers a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, and the pharmaceutical sciences. The main purpose of the present book is to draw on the rich culture, folklore, and biodiversity of immunity-boosting medicinal plants of the Western Himalayas, with particular emphasis on the Indian Trans-Himalayan and Western Himalayan region. All the plants included in the present book are extensively used by the local tribes and people for their health-promoting properties from ancient times. This book will be a substantial contribution to the knowledge of the region and the country. Also, the book will be very useful to scientists, graduates, and undergraduates, along with researchers in the fields of natural products, herbal medicines, ethnobotany, pharmacology, chemistry, and biology. Further, it is an equally significant resource for a person working in different traditional medicinal systems; doctors (especially those engaged in Ayurveda, Chinese traditional medicinal system, Amchi, and allopathy); the pharmaceutical industry (for drug design and synthesis); biochemistry and biotechnology sciences; and the agricultural sciences. .
    Type of Medium: Online Resource
    Pages: XIX, 609 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995019
    URL: https://doi.org/10.1007/978-981-19-9501-9
    DOI: 10.1007/978-981-19-9501-9
    DDC: 615
    Language: English
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    Online Resource
    Nanoformulations in Human Health : Challenges and Approaches (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Therapeutics. ; Pharmacology. ; Therapeutics.
    Description / Table of Contents: Nano-technological Platforms and Manipulations for the Emerging Ocular Manifestations -- Phytonanomedicines as Topical Alternatives for the Treatment of Skin Cancer -- Nano-sized Labile and Particulate Ingredients in Topical Formulations: A Strategic Approach Against Photoageing and Photocarcinogenisis -- Application of Biocompatible Nanocarriers in Glaucoma: Challenges and Advances -- Nano-carriers for Natural Therapeutics in the Management of Neuropathic Pain -- Advances in the Delivery of Therapeutic Peptides -- Nanoformulations and Their Role in Colon Targeting -- Theranostic Nanoformulations: Merging Diagnostics and Therapeutics -- The Role of Nanoformulations in Nose-To-Brain Drug Delivery -- Cubic Lyotropic Liquid Crystalline Nanostructures: A Versatile Platform for Delivery -- Preformulation Challenges: The Concept Behind the Selection, Design, and Preparation of Nanoformulations -- Nanoethosomes for Topical Fungal Therapeutics -- Comparison of Therapeutic Efficiency of Nanoformulations of Curcumin vs. Tetrahydrocurcumin in Various Disorders -- Nanomedicinal Approaches of Phytotherapeutics to Treat Alzheimers Disease -- Nanoparticulate Approaches to Exploit the Pathophysiology of Rheumatoid and Osteoarthritis -- Emerging Nanotechnology in Chronic Respiratory Diseases -- Conventional and Non-conventional Approaches of Site-specific Targeting of Therapeutics in Some Infectious Diseases and Metabolic Disorders -- Nanoformulations in Human Health Conditions: The Paradigm Shift -- Magnetic Nanoparticles Nanoformulation for Alternative Therapy of Cancer by Super-paramagnetic Hyperthermia -- Nano-weapons Against Tuberculosis -- Drug-Excipient Interactions in Nanoformulations with Special Focus on Impurity Control per ICH guidelines.
    Abstract: This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.
    Type of Medium: Online Resource
    Pages: XVIII, 548 p. 106 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030418588
    URL: https://doi.org/10.1007/978-3-030-41858-8
    DOI: 10.1007/978-3-030-41858-8
    DDC: 615
    Language: English
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    Online Resource
    Emerging Technologies for Nanoparticle Manufacturing (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Nanotechnology. ; Nanochemistry. ; Pharmacology. ; Nanotechnology. ; Nanochemistry.
    Description / Table of Contents: Part 1 Introduction and Biomedical Applications of Nanoparticles -- 1. Introduction to Nanomaterials and Nanotechnology -- 2. Biomedical Applications of Nanoparticles -- Part II-Polymeric Nanoparticles -- 3. Nanocrystallization and Nanoprecipitation Technologies -- 4. Microfluidics Technology for Nanoparticles and Equipment-. 5. Production of Nanocomposites via Extrusion Techniques -- 6. The Use of Supercritical Fluids Technologies for Nanoparticle Production -- 7. Salting out and Ionic Gelation Manufacturing Techniques for Nanoparticles -- 8. Nanogel Synthesis by Irradiation of Aqueous Polymer Solutions -- 9. Cellulose acetate based nanofibers: Synthesis, Manufacturing and Applications -- 10. Production of nanofibers, environmental challenges and solutions -- Part III-Lipid Nanoparticles -- 11. High Pressure Homogenization Techniques for Nanoparticles -- 12. Solvent emulsification evaporation and solvent emulsification diffusion techniques for nanoparticles -- 13. Ultrasound Activated Nanoemulsions -- 14. Multiple Emulsions: Emphasizing on industrial applications -- 15. Membrane techniques for the preparation of nanomaterials -- 16. Self-assembling Lipid Nanoparticles/Nanosystems (SLNN) using Hydrophilic Solvents: Overview and Industrial Uses -- 17. Nanoemulsions – An emerging technology in drug delivery -- Part IV- Metallic Nanoparticles -- 18. Manufacturing techniques for carbon nanotubes, gold nanoparticles and silver nanoparticles -- 19. Radio frequency (RF) plasma-based Synthesis of metallic Nano particles for Biomedical Application -- 20. Techniques for accurate sizing of nanoparticles -- 21. Silver nanoparticles synthesis from cyanobacteria: Environmental and biomedical applications -- 22. Selenium Nanoparticles: Green Synthesis and Exploitation -- Part V- Quality control for nanoparticles -- 23. Practical guidelines for the characterization and quality control of nanoparticlesin the pharmaceutical industry -- Part VI-Challenges in scale-up production of nanoparticles -- 24. Nanomedicine Scale-Up Technologies: Feasibilities and Challenges -- 25. Patent survey on recent technology for nanoparticles -- Part VII-Injectable Nanosystems -- 26. Injectable Nanosystems and Inherent Nano-Serum Interactions -- Part VIII- Future directions and challenges -- 27. Current Challenges and Future Directions in Nanomedicine.
    Abstract: This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of Nanoparticles II. Polymeric Nanoparticles III. Lipid Nanoparticles IV. Metallic Nanoparticles V. Quality Control for Nanoparticles VI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and Challenges Leading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges. .
    Type of Medium: Online Resource
    Pages: XV, 611 p. 155 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030507039
    URL: https://doi.org/10.1007/978-3-030-50703-9
    DOI: 10.1007/978-3-030-50703-9
    DDC: 615
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  • 44
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    Online Resource
    Antiviral Drug Discovery and Development (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Biotechnology. ; Pharmacology. ; Pharmacy. ; Biotechnology.
    Description / Table of Contents: 1 Antiviral Drugs Against Herpesviruses -- 2 An Update on Antiretroviral Therapy -- 3 Structural Insights to Human Immunodeficiency Virus (HIV-1) Targets and their Inhibition -- 4 LEDGINs, Inhibitors of the Interaction between HIV-1 Integrase and LEDGF/p75, are Potent Antivirals with a Potential to Cure HIV Infection -- 5 Moving Fast Towards Hepatitis B Virus Elimination -- 6 Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection -- 7 Phytoconstituents as Lead Compounds for Anti-dengue Drug Discovery -- 8 Anti-influenza Drug Discovery and Development: Targeting the Virus and its Host by all -- 9 Search, Identification and Design of Effective Antiviral Drugs against Pandemic Human Coronaviruses -- 10 Peptide Based Antiviral Drugs -- 11 Covalent Antiviral Agents -- 12 Safe-in-Man Broad Spectrum Antiviral Agents -- 13 Exploiting Ubiquitin ligases for Induced Target Degradation as an Antiviral Strategy. .
    Abstract: This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.
    Type of Medium: Online Resource
    Pages: XI, 357 p. 142 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811602672
    Series Statement: Advances in Experimental Medicine and Biology, 1322
    URL: https://doi.org/10.1007/978-981-16-0267-2
    DOI: 10.1007/978-981-16-0267-2
    DDC: 615
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  • 45
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    Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Medical genetics. ; Human physiology. ; Pharmacology. ; Medical Genetics. ; Human Physiology.
    Description / Table of Contents: Preface -- Part 1 Modulation -- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies -- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia -- Sympathetic Nervous System Regulation of Cardiac Calcium Channels -- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19 -- Part 2 Pharmacological Approaches -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits -- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors -- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies -- CACNA1C-Related Channelopathies -- CACNA1D-Related Channelopathies: From Hypertension to Autism -- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options -- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.
    Abstract: The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
    Type of Medium: Online Resource
    Pages: XII, 316 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031384370
    Series Statement: Handbook of Experimental Pharmacology, 279
    URL: https://doi.org/10.1007/978-3-031-38437-0
    DOI: 10.1007/978-3-031-38437-0
    DDC: 615
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  • 46
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    Edible Plants in Health and Diseases : Volume II : Phytochemical and Pharmacological Properties (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: 1 Zingiber officinale - Its Ethanobotanical Uses, Phytochemistry and Pharmacology -- 2 An Insight in to the Phytochemistry, Traditional uses and Pharmacology of Ziziphus spina-christi (L) Willd. (Sidr): An Edible wild plant of Arabian Peninsula -- 3 Traditional Uses, Phytochemistry and Pharmacological Profile of Salvadora persica Linn -- 4 Phytochemistry, Pharmacology and Applications of Ocimum sanctum (Tulsi) -- 5 Nigella sativa: Its Ethnobotany, Phytochemistry and Pharmacology -- 6 A Review on Ethnomedicinal, Phytochemistry and Pharmacological Activities of Rumex hastatus D. Don -- 7 Chemical Composition and Biological Uses of Crocus sativus L.(Saffron) -- 8 Positive Health Benefits of Saponins from Edible Legumes: Phytochemistry and Pharmacology -- 9 Taraxcum officinale: The Esculent Dandelion as Herbal Medicine -- 10 Arctium lappa: A Review on its Phytochemistry and Pharmacology -- 12 Cichorium intybus: A Comprehensive Review on its Pharmacological Activity and Phytochemistry -- 13 Phytochemical and Pharmacological Properties of Picrorhiza kurroa -- 14 Lady's Purse (Capsella bursa-pastoris L.)-Current perspective on its ethanopharmacological, therapeutic potential and phytochemistry -- 15 Ethnopharmaology, Phytochemistry and Biological Activities of Achillea millefolium: A Comprehensive Review -- 16 A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Verbascum thapsus -- 17 Acorus calamus - A Review on Its Phytochemical and Pharmacological Profile.
    Abstract: The book provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits and discuss how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists, and all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: IX, 522 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811649592
    URL: https://doi.org/10.1007/978-981-16-4959-2
    DOI: 10.1007/978-981-16-4959-2
    DDC: 615
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  • 47
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    The Kappa Opioid Receptor (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacology.
    Description / Table of Contents: From the contents. Preface.-Part I: Molecular aspects of KOR -- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals -- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.
    Abstract: This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials. The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XI, 577 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030890742
    Series Statement: Handbook of Experimental Pharmacology, 271
    URL: https://doi.org/10.1007/978-3-030-89074-2
    DOI: 10.1007/978-3-030-89074-2
    DDC: 615
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  • 48
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    Behavioral Neurobiology of GABAB Receptor Function (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Abstract: It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors. The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives. The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.
    Type of Medium: Online Resource
    Pages: VII, 329 p. 70 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030913359
    Series Statement: Current Topics in Behavioral Neurosciences, 52
    URL: https://doi.org/10.1007/978-3-030-91335-9
    DOI: 10.1007/978-3-030-91335-9
    DDC: 615
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  • 49
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    Marine Biomaterials : Drug Delivery and Therapeutic Applications (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Abstract: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 453 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647871
    URL: https://doi.org/10.1007/978-981-16-4787-1
    DOI: 10.1007/978-981-16-4787-1
    DDC: 615
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  • 50
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    Online Resource
    Parkinsonism and the Environment (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Neurosciences. ; Pharmacology. ; Neuroscience.
    Description / Table of Contents: Experimental evidence for pesticide contribution in the pathogenesis of Parkinsonism: an update -- Epidemiological evidence for pesticide involvement in the etiology of Parkinson’s Disease: current state of affairs?” -- Manganese induced Parkinsonism: cellular and molecular mechanisms -- Manganese overexposures in occupational and environmental settings and Parkinsonism: where do we stand -- Aberrant dopamine metabolism as a focal point in the mechanism of environmental contaminant-induced dopaminergic dysfunction -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Protein kinase C-delta (PKC-delta): a major molecular target for disparate dopaminergic toxicants -- Environmental contribution to redox dyshomeostasis in Parkinsonism.
    Abstract: “The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”.
    Type of Medium: Online Resource
    Pages: V, 158 p. 14 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874513
    Series Statement: Molecular and Integrative Toxicology,
    URL: https://doi.org/10.1007/978-3-030-87451-3
    DOI: 10.1007/978-3-030-87451-3
    DDC: 615
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  • 51
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    Ethnopharmacology and Drug Discovery for COVID-19: Anti-SARS-CoV-2 Agents from Herbal Medicines and Natural Products (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Nanobiotechnology. ; Bioinformatics. ; Diseases Causes and theories of causation. ; Molecular biology. ; Pharmacology. ; Natural Products. ; Nanobiotechnology. ; Bioinformatics. ; Pathogenesis. ; Molecular Biology.
    Description / Table of Contents: 1. COVID-19: An overview of virology, mutations, pathology, epidemiology, diagnosis, preventions and treatments -- 2. The recent development of therapeutic strategies against COVID-19 -- 3. Plant immunoenhancers: Promising ethnopharmacological candidates for anti-SARS-CoV-2 activity -- 4. Herbal formulations in fighting against the SARS-CoV-2 infection -- 5. Rejuvenation of traditional medicine in the 21st century against SARS-CoV-2 -- 6. Traditional herbal medicines and their active constituents in combating SARS-CoV-2 infection -- 7. Antiviral phytocompounds against animal-to-human transmittable SARS-CoV-2 -- 8. Plants-derived bioactive compounds as potential ACE-2 inhibitors against SARS-CoV-2 infection -- 9. Insights into in silico methods to explore plant bioactive substances in combating SARS-CoV-2 -- 10. Dietary plants, spices and fruits in curbing SARS-CoV-2 virulence -- 11. Therapeutic potential of selected medicinal plants for neurological disorders after the infection of COVID-19 -- 12. Glycyrrhizae Radix et Rhizoma (Gan Cao) for the management of COVID-19 -- 13. COVID-19-induced kidney disease: Ethnopharmacological intervention to ameliorate kidney damage and improve kidney function -- 14. Phytochemicals and nutraceuticals targeting SARS-CoV-2: An in silico analysis -- 15. Therapeutic and prophylactic effects of plant derivatives against SARS-CoV-2 -- 16. Therapeutic potential of essential oils against SARS-CoV-2 infection -- 17. Antiviral properties of South Indian plants against SARS-CoV-2 -- 18. Immune-boosting plants used in Turkish folk medicine and their potential against COVID-19 -- 19. A comparison study of medicinal plants used against SARS-CoV-2 and those recommended against malaria in Africa -- 20. Exploring the potential antiviral properties of Nigella sativa L. against SARS-CoV-2: Mechanisms and prospects -- .
    Abstract: This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
    Type of Medium: Online Resource
    Pages: IX, 590 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936649
    URL: https://doi.org/10.1007/978-981-99-3664-9
    DOI: 10.1007/978-981-99-3664-9
    DDC: 615
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    Novel Drug Targets With Traditional Herbal Medicines : Scientific and Clinical Evidence (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Natural products. ; Pharmacology. ; Toxicology. ; Pharmaceutics. ; Medicinal Chemistry. ; Natural Products.
    Description / Table of Contents: Chapter 1: Achillea biebersteinii Afan -- Chapter 2: Aesculus hippocastanum L. -- Chapter 3: Berberis crataegina DC. -- Chapter 4: Calendula officinalis L. -- Chapter 5: Camellia sinensis (L.) Kuntze -- Chapter 6: Capsella bursa-pastoris (L.) Medik. -- Chapter 7: Capsicum annuum L. -- Chapter 8: Cedrus libani A.Rich. -- Chapter 9: Chelidonium majus L. -- Chapter 10: Cichorium intybus L. -- Chapter 11: Cistus laurifolius L. -- Chapter 12: Coriandrum sativum L. -- Chapter 13: Cornus mas L. -- Chapter 14: Curcuma longa L..-Chapter 15: Cydonia oblonga Mill. -- Chapter 16: Cynara scolymus L. -- Chapter 17: Equisetum arvense L. -- Chapter 18: Foeniculum vulgare Mill. -- Chapter 19: Fraxiınus ornus L. -- Chapter 20: Fumaria officinalis L. -- Chapter 21: Helichrysum plicatum DC. -- Chapter 22: Hyoscyamus niger L. -- Chapter 23: Juglans regia L. -- Chapter 24: Laurus nobilis L. -- Chapter 25: Liquidambar orientalis Miller -- Chapter 26: Matricaria chamomilla L. -- Chapter 27: Melissa officinalis L. -- Chapter 28: Momordica charantia L. -- Chapter 29: Nigella sativa L. -- Chapter 30: Olea europaea L. -- Chapter 31: Papaver somniferum L. -- Chapter 32: Rheum ribes L. -- Chapter 33: Rosa canina L. -- Chapter 34: Rosmarinus officinalis L. -- Chapter 35: Silybum marianum L. Gaertn. -- Chapter 36: Urtica dioica L -- Chapter 37: Valeriana officinalis L. -- Chapter 38: Viburnum opulus L.
    Abstract: This book collects information about the most popular ethnomedicinal plants, which are common in Turkey and around the world. It presents the ethnopharmacological records, in vivo and in vitro studies, side effects, chemical compositions and clinical studies of these medicinal plants. Its special focus is on the novel drug targets for disease and their possible mechanisms of action. It covers botanical descriptions the status of the plants, and food or drug interactions including precautions and warnings about the plants and the available market products. It provides an explanation of recorded and known plant administration dosages. Also, the gap between the traditional practice and scientific/clinical evidences in the use of ethnomedicinal plant is acknowledged. It is well known that traditional knowledge of the use of the medicinal plants in therapy is an important resource for the discovery of novel treatment options and drug targets. The main purpose of this book is to draw attention to ethnomedicinal plant species. Data on the therapeutic potentials of these medicinal plants can now be accessed from a single source. It provides an important resource for future research opportunities for harnessing the full potential of these plants.
    Type of Medium: Online Resource
    Pages: XII, 588 p. 119 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031077531
    URL: https://doi.org/10.1007/978-3-031-07753-1
    DOI: 10.1007/978-3-031-07753-1
    DDC: 615
    Language: English
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    Herb-Drug Combinations : A New Complementary Therapeutic Strategy (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Alternative medicine. ; Pharmacovigilance. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion.
    Abstract: Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811951251
    URL: https://doi.org/10.1007/978-981-19-5125-1
    DOI: 10.1007/978-981-19-5125-1
    DDC: 615
    Language: English
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    Sex and Gender Effects in Pharmacology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Immunology. ; Neurology . ; Endocrinology. ; Cardiology. ; Pharmacology. ; Immunology. ; Neurology. ; Endocrinology. ; Cardiology.
    Description / Table of Contents: Part 1 Pharmacological Basic Principles -- The impact of sex and gender in medicine and pharmacology -- Sex differences in pharmacokinetics -- Clinical pharmacological considerations in transgender medicine -- Sex and gender differences in the pharmacology of the overactive urinary bladder -- Part 2 Pathologies of the Brain -- Sex differences in the evaluation and treatment of stroke -- Sex differences in pain and its treatment -- Therapeutics For Substance-Using Women: The Need To Elucidate Sex-Specific Targets For Better-Tailored Treatments -- Intersection of sex and depression: pathogenesis, presentation and treatments -- Biological and clinical implications of sex-specific differences in Alzheimer’s disease -- Part 3 Diabetes, metabolic diseases & cardiovascular risk -- Gender Differences In Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management. - Sex Differences in Glucose Homeostasis -- Sex-gender-based differences in metabolic diseases -- Hypothalamic pituitary gonadal axis disorders impacting fertility in both sexes and the potential of kisspeptin-based therapies to treat them.
    Abstract: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031426483
    Series Statement: Handbook of Experimental Pharmacology, 282
    URL: https://doi.org/10.1007/978-3-031-42648-3
    DOI: 10.1007/978-3-031-42648-3
    DDC: 615
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    Water Resources of Lebanon (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental management. ; Bioclimatology. ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Environmental monitoring. ; Water. ; Environmental Management. ; Climate Change Ecology. ; Freshwater and Marine Ecology. ; Pollution. ; Environmental Monitoring.
    Description / Table of Contents: Foreword -- Preface -- Chapter 1 Introduction.-Chapter 2 Atmospheric Regime and Terrain Characteristics -- Chapter 3 Rivers -- Chapter 4 Springs -- Chapter 5 Snow Cover -- Chapter 6 Lakes and Reservoirs -- Chapter 7 Wetlands -- Chapter 8 Groundwater -- Chapter 9 Challenges on Water Resources -- Chapter 10 Proposed Solutions -- Glossary.
    Abstract: Water has become a challenging resource that many countries worldwide are concerned with. Thus, water is often linked with health, society development, national income and even international geo-politics. Sometimes, water resources are unavailable, but successful management involves developing approaches and projects to assure water supply. However, there are some countries with available water resources, but unsatisfactory management, and thus complain about water supply becoming a national problem. This situation is prevalent in Lebanon, a country characterized by abundant water resources whether on the surface or sub-surface. It is a paradox that there is still imbalance in water supply/demand in Lebanon, and water resources are now under stress due to chaotic use. This has been exacerbated by the oscillating climatic conditions, increased population and improper management. Therefore, people receive less than one-third of their water needs, and most water supplied is of poor quality. The current status shows a descending trend. Undoubtedly, if the water sector in Lebanon continues this way, we should anticipate unfavourable (and may be severe) consequences. Many studies have been conducted on water and related disciplines in Lebanon; however, all of them focus on specific themes and sometimes defined regions. Nevertheless, the occurred changes on the influencers (natural and man-made) have not been considered. This book is the first of its type for Lebanon, and it shows all aspects of water resources with updated measurements and findings obtained by adopting new techniques. It diagnoses in-depth the major elements of water flow/storage mechanism that have never been covered in such a comprehensive manner before. Also, this book introduces and analyses the existing challenges and proposes solutions. It represents a comprehensive investigation of the water resources in Lebanon.
    Type of Medium: Online Resource
    Pages: XIII, 229 p. 87 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030487171
    Series Statement: World Water Resources, 7
    URL: https://doi.org/10.1007/978-3-030-48717-1
    DOI: 10.1007/978-3-030-48717-1
    DDC: 551.48
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    Sustainability of Groundwater in the Nile Valley, Egypt (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Geology. ; Geotechnical engineering. ; Water. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Introduction -- Evaluation of Groundwater Resources in West of the Nile Valley, Egypt: A Comprehensive Review -- Fundamentals of Groundwater Modeling Methods and a Focused Review on the Groundwater Models of the Nile Valley Aquifer -- Contamination Sources Along the Nile Valley, Egypt and Its Impact on Groundwater -- Environmental Impacts of Treated Wastewater Contaminates on Groundwater Quality in the Nile River Valley, Egypt.
    Abstract: Groundwater is the world’s largest source of fresh water, but its safe and sustainable exploitation remains a challenge. Egypt's Nile Valley aquifer is the most important renewable aquifer, accounting for approximately 85% of total groundwater use in Egypt. Egypt's long-term development and socioeconomic growth in the Nile Valley depends on this groundwater. Concerns about groundwater assessment, quality, management, and sustainability frame the current status of Nile Valley groundwater supplies. Proper knowledge of the current state of the groundwater quantity and quality in the Nile Valley is vital for the development and management of groundwater resources in Egypt. Due to Egypt's water scarcity, the projected decline in Nile River flow due to climate change, and the development of numerous Nile River basin projects, the situation is critical, and the consequences might be severe. Furthermore, Egypt's growing population puts significant strain on groundwater, which is the second most significant freshwater supply next to the surface water supply coming from the Nile River as Egypt’s share. Several books on the various aspects of Egypt's water resources have been published, but there is insufficient recent information on groundwater in the Nile Valley aquifer, which is essential for Egyptian populations for domestic and irrigation purposes. As a result, this book on the groundwater in the Nile Valley aquifer emerges to complete the picture of Egypt’s water resources as a good example of arid country located in MENA regions with many arid countries. Consequently, the lessons learned from this book could be beneficial to other countries in MENA regions, particularly those in North Africa.
    Type of Medium: Online Resource
    Pages: VIII, 354 p. 150 illus., 146 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031126765
    Series Statement: Earth and Environmental Sciences Library,
    URL: https://doi.org/10.1007/978-3-031-12676-5
    DOI: 10.1007/978-3-031-12676-5
    DDC: 551.48
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    Fluvial Systems in the Anthropocene : Process, Response and Modelling (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Physical geography. ; Sedimentology. ; Ecology . ; Water. ; Physical Geography. ; Sedimentology. ; Ecology.
    Description / Table of Contents: 1. Discoursing River from Physical and Social Backdrops -- 2. Rivers in Distress : A Geo-Ecological consideration -- 3. Incorporating hydromorphological assessments in the fluvial geomorphology domain for transitioning towards Restorative River Science – Context, Concepts and Criteria -- 4. The Role of Rivers on Man and Society reflected in Literature: A critical study of a few selected River-oriented popular Bengali Novels in Geographical Perspective -- 5. An assessment of human impact on Bhagirathi river in Murshidabad district : From reverence to responsibility. .
    Abstract: This book addresses the various factors affecting fluvial systems, the processes governing them, system responses arising from human-nature interventions, and geospatial and geo-ecological modeling to understand system behaviour better and restore degraded ecosystems around the globe. Thanks to their hydrological and agro-ecological advantages, humans have settled along riverbanks since the dawn of civilization. Thus, the ancient "ecumene" (settlements) were located near major rivers worldwide. This legacy of river-based civilizations continues to this day in many forms. However, in the course of the 'Anthropocene' era, countless fluvial systems have been altered by human interventions in the form of large-scale dams and barrages, changes in land use and land cover, road-stream crossings, mining of sand and gravel, mushrooming of brickfield, expansion of modern agriculture, industrial growth, and urbanization. Thus, the present-day development pattern threatens fluvial systems, especially riverine morphology and ecosystems. In brief, human-induced morphological changes, water pollution, eutrophication, and related damages to aquatic organisms are the major threats to fluvial systems. Thus, maintaining the 'environmental flow' of the world's major rivers to preserve the proper functioning of riverine ecosystems and promote sustainable development is a global challenge.
    Type of Medium: Online Resource
    Pages: XVIII, 487 p. 160 illus., 150 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031111815
    URL: https://doi.org/10.1007/978-3-031-11181-5
    DOI: 10.1007/978-3-031-11181-5
    DDC: 551.48
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    Soil-Water, Agriculture, and Climate Change : Exploring Linkages (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Agriculture. ; Climatology. ; Machine learning. ; Environmental economics. ; Water. ; Agriculture. ; Climate Sciences. ; Machine Learning. ; Environmental Economics.
    Description / Table of Contents: Understanding Hydrology of Indian Himalayan landscapes- A Review -- Development of a semi-distributed rainfall-runoff model for water budgeting in macropore dominated hilly river basins -- Hydrological Simulation Using Coupled ANN-SCS Approach in Pagladiya Watershed: A Sub-catchment of Brahmaputra River Basin -- Water erosion risks mapping using RUSLE model in the Mohamed Ben Abdelkrim El Khattabi Dam watershed (Central Coastal Rif, Morocco).
    Abstract: This book presents an exploration of linkages among soil-water, agriculture, and climate change with a special focus on thematic areas for assessment, mitigation, and management of natural resources under climate change conditions. This book covers advances in modelling approaches, including machine learning (ML)/ artificial intelligence (AI) applications; GIS and remote sensing; sensors; impacts of climate change on agriculture; subsurface water; contaminants; and socio-economic impacts, which are lacking in a more comprehensive manner in the previous titles. This book encompasses updated information as well as future directions for researchers working in the field of management of natural resources. The goal of this book is to provide scientific evidence to researchers and policymakers and end-to-end value chain practitioners which may help in reducing the overall adverse impacts of climate change on water resources and the related mitigation strategies. This book focuses on the knowledge, modern tools, and techniques, i.e., machine learning, artificial intelligence, etc. for soil-water, agriculture, and climate change. Further, nature-based solutions for management of natural resources with special targets on contaminants, extreme events, disturbances, etc. will be targeted. The book provides readers with the enhanced knowledge for application of engineering principles and economic and regulatory constraints to determine a soil-water, agriculture production action strategy, and select appropriate technologies to implement the strategy for a given data set at a site. It would also cover the application of laboratory, modeling, numerical methods for determination and forecasting of climate change impacts, agriculture production, pollution, soil health, etc. Overall, it provides hydrologists, environmental engineers, administrators, policy makers, consultants, and industrial experts with essential support in effective management of soils health, agricultural productions, and mitigation of extreme climatic events.
    Type of Medium: Online Resource
    Pages: XI, 376 p. 81 illus., 80 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031120596
    Series Statement: Water Science and Technology Library, 113
    URL: https://doi.org/10.1007/978-3-031-12059-6
    DOI: 10.1007/978-3-031-12059-6
    DDC: 551.48
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    Urban Mountain Waterscapes in Leh, Indian Trans-Himalaya : The Transformation of Hydro-Social Relations (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Sociology, Urban. ; Geography. ; Human geography. ; Water. ; Urban Sociology. ; Regional Geography. ; Human Geography.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Perspectives on Hydro-Social Relations in Urban Mountain Contexts. Chapter 3. Research Design -- Chapter 4. Socio-Environmental Context of Urban Waterscapes in Leh -- Chapter 5. Urbanisation and the Impact on Water Use in Leh -- Chapter 6. Discussion: The Uneven Waterscape of Leh -- Chapter 7. Conclusion.
    Abstract: The city of Leh is located in the high mountain desert of Ladakh in the Indian Himalayas and access to water has always been limited there. In recent years, the town has experienced high rates of urbanisation on the one hand, and tourist numbers have increased exponentially on the other, which has implications for the water supply of the people living there. Through several years of on-site research, challenges on various levels were documented and current governance approaches were analysed. This research forms the basis for future approaches to sustainable development.
    Type of Medium: Online Resource
    Pages: XVI, 181 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031182495
    Series Statement: Advances in Asian Human-Environmental Research,
    URL: https://doi.org/10.1007/978-3-031-18249-5
    DOI: 10.1007/978-3-031-18249-5
    DDC: 551.48
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    South Africa’s Water Predicament : Freshwater’s Unceasing Decline (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Sustainability. ; Pollution. ; Environment. ; Environmental policy. ; Water. ; Sustainability. ; Pollution. ; Environmental Sciences. ; Environmental Policy.
    Description / Table of Contents: Introduction -- 1: Water Resources from a Global Perspective -- 2: Necessity of IWRM and Water Services -- 3: South Africa’s Continued Freshwater Decline and Current State -- 4: Decline in Informed Water Management -- 5: Continued Lack of Water Service Delivery -- 6: Progressive Deterioration of Water Quality -- 7: Main Issues Requiring Attention and Addressing Continued Deterioration -- 8: Transforming the Predicament into Problems.
    Abstract: The book provides a critical evaluation of South Africa’s freshwater resources to illustrate the way in which its freshwater resources, water access, services and infrastructure have continued to decline over the past three decades. The continued decline of water governance, management, water service delivery, dilapidated water infrastructure, dysfunctional local governments and overall excessive water degradation is illustrated and emphasized using real-life examples and case studies from various contexts within the country. The main argument of the book is that South Africa’s freshwater resources have declined to such an extent that it can be described as a predicament. Questionable water governance decisions and reactive water management practices have led to no improvement and/or increased degradation of freshwater resources. An overall lack of service delivery exists across the country, in various contexts, leading to further water and social decline. An inter-disciplinary evaluation of South Africa’s current water predicament is provided, major water crises are prioritized, and suitable recommendations are given to transform its predicament into problems which can be addressed. Suitable background information is given to emphasize the necessity of good water governance, management, and service delivery. South Africa’s freshwater resources are evaluated with specific focus on the decline of informed water governance, management, service delivery and water quality. Factors requiring urgent attention are determined and suitable recommendations and/or actions are provided. An evaluation and overall synthesis focused on the transformation of the predicament into problems is provided. Primary water problems are prioritized according to urgency and suitable recommendations are given to assist in transforming the country’s current complex water predicament into “simpler” water problems. Political will, collaboration with researchers, stakeholders, non-governmental organizations, and cooperation of civil society is required. South Africa’s already scarce freshwater resources and decaying infrastructure will persist and possibly collapse if no major actions or interventions are implemented. .
    Type of Medium: Online Resource
    Pages: XVIII, 177 p. 30 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031240195
    Series Statement: Water Science and Technology Library, 101
    URL: https://doi.org/10.1007/978-3-031-24019-5
    DOI: 10.1007/978-3-031-24019-5
    DDC: 551.48
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    Groundwater and Society : Applications of Geospatial Technology (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Geographic information systems. ; Sustainability. ; Environmental protection. ; Civil engineering. ; Water. ; Geographical Information System. ; Sustainability. ; Soil and Water Protection.
    Description / Table of Contents: Chapter 1. Introduction: Groundwater and Society: Applications of Geospatial Technology (Pravat Kumar Shit, Gouri Sankar Bhunia, Partha Pratim Adhikary, Ch. Jyotiprava Dash) -- Part I: Groundwater resources and societal development -- Chapter 2. Groundwater and Society in India: Challenging Issues and Adaptive Strategies (Subrata Jana) -- Chapter 3. Groundwater Research and Societal Development: Integration with Remote Sensing and Geographical Information System (Gouri Sankar Bhunia, Pravat Kumar Shit, Partha Pratim Adhikary and Debashish Sengupta) -- Chapter 4. Geospatial and Geophysical Approaches for Assessment of Groundwater Resources in an Alluvial Aquifer of India (Partha Pratim Adhikary, S.K.Dubey, Debashis Chakraborty, Ch. Jyotiprava Dash) -- Chapter 5. Groundwater and Space Technology: Issues and challenges (Gouri Sankar Bhunia, Pravat Kumar Shit, Harsha Das Gupta, Partha Pratim Adhikary) -- Part II: Groundwater availability, quality and pollution -- Chapter 6. Groundwater Quality through Multi-criteria based GIS Analysis: Village Level Assessment (Baisakhi Chakraborty, Sambhunath Roy, Gouri Sankar Bhunia, Debashish Sengupta, Pravat Kumar Shit) -- Chapter 7. GIS-based Fuzzy-AHP Approach for Assessment of Groundwater Potential Zones of an Urban Agglomeration (Suraj Kumar Mallick, Somnath Rudra) -- Chapter 8. Assessment of Groundwater Availability in Gumani River Basin, India using Geoinformatics and Analytical Hierarchy Process (Sadik Mahammad, Aznarul Islam) -- Chapter 9. Application of AHP for Groundwater Potential Zones Mapping in Plateau Fringe Terrain: Study from Western Province of West Bengal (Manas Karmakar, Monali Banerjee, Mrinal Mandal, Debasis Ghosh) -- Chapter 10. Performance of Frequency Ratio Approach for Mapping of Groundwater Prospect Areas in an Area of Mixed Topography (Subhas Garai, Pulakesh Das) -- Chapter 11. Artificial Neural Network for Identification of Groundwater Potential Zones in part of Hugli District, West Bengal, India (Chalantika Laha Salui and Shashank Yadav) -- Chapter 12. Multi-criteria Analysis for Groundwater Quality Assessment: A Study in Paschim Barddhaman District of West Bengal, India (Payel Das, Niladri Das) -- Chapter 13. Performance of WQI and HPI for Groundwater Quality Assessment: Study from Sangramgarh Colliery of West Burdwan District, West Bengal, India (Tanushree Paul, Manas Nath) -- Chapter 14. Assessment of Groundwater Quality interaction using One-decade Data: Case Study from a Hard Rock Area (S. Satheeshkumar, S. Venkateswaran, T. Maheshwari) -- Chapter 15. Fluoride Dynamics in Precambrian Hard Rock Terrain of North Singbhum Craton and Effect of Fluorosis on Human Health and Society (Biswajit Bera, Sumana Bhattacharjee, Meelan Chamling, Arijit Ghosh, Nairita Sengupta, Supriya Ghosh) -- Chapter 16. Coastal Aquifer Vulnerability for Saltwater Intrusion: A Case Study of Chennai Coast Using GALDIT Model and Geoinformatics (Debabrata Ghorai, Gouri Sankar Bhunia, Pravat Kumar Shit) -- Part III: Sustainable Groundwater resources management -- Chapter 17. Watershed Development Impact on Natural Resources: Groundwater and Surface Water Utilization (Partha Pratim Adhikary, M. Madhu, P. Jakhar, B.S. Naik, H.C. Hombegowda, D. Barman, G.B. Naik, Ch. J. Dash) -- Chapter 18. Long-term Groundwater Behaviour over an Agriculturally Developed State of North-West India: Trend and Impact on Agriculture (Omvir Singh, Amrita Kasana, Pankaj Bhardwaj) -- Chapter 19. Spatial Appraisals of Groundwater Recharge Potential Zone Identification using Remote Sensing and GIS (Gouri Sankar Bhunia, Pranab Kumar Maity, Pravat Kumar Shit) -- Chapter 20. Spatial Mapping of Groundwater Depth to Prioritize the Areas under Water Stress in Rayalaseema Region of Andhra Pradesh, India (Ch. Jyotiprava Dash, PP Adhikary, Uday Mandal) -- Chapter 21. Exploring Vulnerability of Groundwater using AHP and GIS Techniques: A Study in Cooch Behar District, West Bengal, India (Dipankar Saha, Debasish Talukdar, Ujjal Senapati, Tapan Kumar Das) -- Chapter 22. Applicability of Geospatial Technology, Weight of Evidence and Multilayer Perceptron for Groundwater Management: A Geoscientific Study on Birbhum District, West Bengal, India (Niladri Das, Subhasish Sutradhar, Ranajit Ghosh, Prolay Mondal) -- Chapter 23. Water resources management in semi-arid Purulia District of West Bengal, in the context of sustainable development goals (Amit Bera, Shubhamita Das).
    Abstract: This volume advances the scientific understanding, development, and application of geospatial technologies related to groundwater resource management, mapping, monitoring, and modelling using up-to-date remote sensing and GIS techniques. The book further provides a critical analysis of the debates and discourses surrounding groundwater resources and society, illustrates the relationship between groundwater resources and precision agriculture for societal development, and describes novel, region-specific management strategies and techniques for sustainability with case studies. The book is organized into three parts: (I) Groundwater resources and societal development; (II) Groundwater availability, quality and pollution; and (III) Sustainable groundwater resources management. Each section begins with a short introduction that includes an overview of the papers in that section. Individual chapters focus on the core themes of research and knowledge along with some topics that have received lesser attention. The book will be of interest to water resource planners and decision-makers, academic researchers, policy makers, NGOs, and academic researchers and students in Geography, Geophysics, Hydrology, Remote Sensing & GIS, Agriculture, Soil Science, and Agronomy.
    Type of Medium: Online Resource
    Pages: XVI, 534 p. 215 illus., 199 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030641368
    URL: https://doi.org/10.1007/978-3-030-64136-8
    DOI: 10.1007/978-3-030-64136-8
    DDC: 551.48
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    Reclaiming and Rewilding River Cities for Outdoor Recreation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Urban ecology (Biology). ; Sociology, Urban. ; Biotic communities. ; Tourism. ; Management. ; Water. ; Urban Ecology. ; Urban Sociology. ; Ecosystems. ; Tourism Management.
    Description / Table of Contents: Introduction. Reclaiming and rewilding river cities for outdoor recreation -- Cities and their waterways -- With rivers to the sea: Ecological restoration of rivers and estuaries and nature-based activities -- Behind good ecological status, the quest to reconquer water territories -- Planning and designing facilities that enhance rivers and encourage the development of tourist and recreational spaces: urban promenades -- Outdoor leisure activities at odds with the city. Arcachon Bay and the Massif des Calanques -- “On the conquest of wild nature” ... but what is meant by ‘nature’? -- The Darsena di Milano (Italy): ‘restoration’ of an urban artificial aquatic environment between citizens' hopes and municipal projects -- Grenoble, the river city facing the mountains (End 19th century-1930s) -- The role and significance of the recreational reconquest of port spaces: Rouen (France), reinvention at the neck of the estuary -- Recreational Activities, Economic and Territorial Development: Caen (France) in the Reconquest of its River? -- Bordeaux’s playful and sporty maritime life: a revolution of venues and activities.
    Abstract: The introduction of sports and recreational facilities into natural environments calls for reflection on their impact on fragile ecosystems. This book is unique in providing an interdisciplinary approach to the ecological restoration of urban and industrial degraded habitats and their use by nearby city-dwellers. For the first time ecologists, sociologists and anthropologists have worked together on particularly sensitive ecosystems such as rivers and estuaries to propose recovery strategies that allow their basic ecological functions to be restored, and which can benefit local populations through nature activities. Nonetheless, the use of natural spaces calls for the building of sustainable towns. This is why this book is distinctive in considering quality of life and well-being as stated objectives of modern river towns. Recently, leisure time has become a part of urban rhythms. In order to favour personal development, an extensive palette of leisure activities is considered by the authors: bird watching entertainment sports culture Many aspects including physical and psychological attributes in relation to the contemporary socio-political fabric are dealt with. While creating areas of freedom, landscaping also induces certain forms of practice and encourages certain social skills. Conversely, the book questions certain types of management based on mass consumption. Don’t they, in the end, aim to satisfy needs that are impermanent and shallow? The image of the contemporary town relies on urban planning projects which, in a global economy, seek to capture the interest of tourists and local populations. How can suitable, diligent planning be successfully combined with both creative design and ecological care? This book demonstrates how biology and sociology can (and should) work in harmony in order to promote an ecosystem approach to environmental management.
    Type of Medium: Online Resource
    Pages: V, 104 p. 38 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030487096
    Series Statement: Estuaries of the World,
    URL: https://doi.org/10.1007/978-3-030-48709-6
    DOI: 10.1007/978-3-030-48709-6
    DDC: 551.48
    Language: English
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    Climate Change Impacts on Water Resources : Hydraulics, Water Resources and Coastal Engineering (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Earth sciences. ; Physical geography. ; Natural disasters. ; Water. ; Earth Sciences. ; Earth System Sciences. ; Natural Hazards.
    Description / Table of Contents: Trend analyses of seasonal mean temperature Series pertaining to Tapi river basin, using monthly data -- . Dry and wet spell characterization of Naini river basin, western Maharashtra, India -- Assessment of Climate Change on Crop Water Requirement in Tandula Command of Chhattisgarh (India) -- Impact of climate change on hydrological regime of Narmada river basin -- Climate change impacts on water resource in Ethiopia -- Spatio-temporal trend analysis of long term IMD gridded precipitation in Godavari river basin, India -- Forecasting reference evapotranspiration using artificial neural network for Nagpur Region -- Assessment of extremes using time varying downscaling model -- Assessment of impact of land use land cover and climate change on quality of river using water quality index -- Assessment of tail behavior of probability distributions of daily precipitation data over India -- Probabilistic prediction of monthly streamflow using graphical modeling approach. .
    Abstract: This book provides insights and a capacity to understand the climate change phenomenon, its impact on water resources, and possible remedial measures. The impact of climate change on water resources is a global issue and cause for concern. Water resources in many countries are extremely stressed, and climate change along with burgeoning populations, the rise in living standards, and increasing demand on resources are factors which serve to exacerbate this stress. The chapters provide information on tools that will be useful to mitigate the adverse consequences of natural disasters. Fundamental to addressing these issues is hydrological modelling which is discussed in this book and ways to combat climate change as an important aspect of water resource management.
    Type of Medium: Online Resource
    Pages: XVI, 551 p. 223 illus., 199 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030642020
    Series Statement: Water Science and Technology Library, 98
    URL: https://doi.org/10.1007/978-3-030-64202-0
    DOI: 10.1007/978-3-030-64202-0
    DDC: 551.48
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  • 64
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    Online Resource
    Emerging Contaminants Vol. 2 : Remediation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Environmental chemistry. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Environmental Chemistry. ; Waste Management/Waste Technology.
    Description / Table of Contents: Preface -- Chapter 1 Emerging Contaminants: Remediation -- Chapter 2 Electrochemical Treatments for the Removal of Emerging Contaminants -- Chapter 3 Technologies to Remove Selenium From Water and Wastewater -- Chapter 4 Advanced Treatments for the Removal of Alkylphenols and Alkylphenol Polyethoxylates from Wastewater -- Index.
    Abstract: Emerging contaminants are chemical and biological agents for which there is growing concern about their potential health and environmental effects. The threat lies in the fact that the sources, fate and toxicology of most of these compounds have not yet been studied. Emerging contaminants, therefore, include a large number of both recently discovered and well-known compounds such as rare earth elements, viruses, bacteria, nanomaterials, microplastics, pharmaceuticals, endocrine disruptors, hormones, personal care products, cosmetics, pesticides, surfactants and industrial chemicals. Emerging contaminants have been found in many daily products, and some of them accumulate in the food chain. Correlations have been observed between aquatic pollution by emerging contaminants and discharges from wastewater treatment plants. Most actual remediation methods are not effective at removing emerging contaminants. This second volume presents comprehensive knowledge on emerging contaminants with a focus on remediation.
    Type of Medium: Online Resource
    Pages: XVI, 401 p. 65 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030690908
    Series Statement: Environmental Chemistry for a Sustainable World, 66
    URL: https://doi.org/10.1007/978-3-030-69090-8
    DOI: 10.1007/978-3-030-69090-8
    DDC: 551.48
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    Online Resource
    Development and Implementation of Ship BWMS (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Marine engineering. ; Water. ; Marine Engineering.
    Description / Table of Contents: Introduction -- Ship ballast water management system -- Working Principle of ballast water management system -- The key components of the system and the working principle of the unit -- Design method of key components -- Optimization of key components -- Development of control system for ballast water management system -- Maintenance and management of ballast water management system -- Implementation of ballast water management system on ships.
    Abstract: This book introduces the components and principles of the common ballast management systems. The working principles of different filtration, cleaning and sterilizing equipment are also introduced. The calculation norm of the construction design and the calculation method of simulation are described. Besides, different aspects of system management are analyzed. The principle of various detecting sensors, the hardware of control system and the design method of human–computer interface are respectively introduced. Last but not least, the maintenance and management of ballast water management system are described, mainly the maintenance and management of key components which composes the system. .
    Type of Medium: Online Resource
    Pages: IX, 285 p. 233 illus., 172 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813368651
    URL: https://doi.org/10.1007/978-981-33-6865-1
    DOI: 10.1007/978-981-33-6865-1
    DDC: 551.48
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  • 66
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    Climate Impacts on Water Resources in India : Environment and Health (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental health. ; Environmental monitoring. ; Bioclimatology. ; Refuse and refuse disposal. ; Water. ; Environmental Health. ; Environmental Monitoring. ; Climate Change Ecology. ; Waste Management/Waste Technology.
    Description / Table of Contents: Foreword -- Preface -- 1. Water Pollution and Water Quality Assessment, Environmental Flows -- 2. Water Treatment Technologies and Management -- 3. Climate Change and Climate Variability -- 4. Water and Human Health Issues -- 5. Conclusions. .
    Abstract: This book chiefly focuses on environmental flow, water pollution and water quality. Several chapters also cover water treatment technologies and management. In today’s context, climate change and climate variability are important issues in the water sector, which is called upon to develop adaptation strategies to cope with their negative impacts. Human health depends upon the quality of water used for drinking and irrigation purposes. These core issues are discussed and addressed in several chapters. The book explores the impact of climate change on water resources and considers various climatological scenarios. In this regard, it carries out a trend analysis and compares the performance of various Global Climate Models (GCMs). Further, it conducts a water quality analysis and water quality mapping so as to provide information on the most vulnerable areas in the context of water quality. Emerging pollutants, generated from paper mills, are identified in order to choose an appropriate treatment technology. Bioremediation techniques are included for the characterization of improved water quality parameters. The book also presents a low-cost treatment technology for fluoride removal, which can help water managers ensure potable water to stakeholders. In terms of maintaining river ecology in the downstream areas of water resources project sites, the book provides a number of case studies on assessment of environmental flows. Advanced treatment technologies that can be highly advantageous for removing water pollutants are presented. Given its scope, the book offers a valuable resource for academics, water resources practitioners, scientists, water managers, environmentalists, administrators, NGOs, researchers and students who are involved in water management with a main focus on water pollution, the environment, climate change and health. .
    Type of Medium: Online Resource
    Pages: XIII, 392 p. 142 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030514273
    Series Statement: Water Science and Technology Library, 95
    URL: https://doi.org/10.1007/978-3-030-51427-3
    DOI: 10.1007/978-3-030-51427-3
    DDC: 551.48
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    Changjiang Riverine and Estuarine Hydro-morphodynamic Processes : In the Context of Anthropocene Era (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Environmental geography. ; Geomorphology. ; Sedimentology. ; Geology. ; Landscape ecology. ; Water. ; Integrated Geography. ; Geomorphology. ; Sedimentology. ; Geology. ; Landscape Ecology.
    Description / Table of Contents: Changjiang River basin Overview -- Hydrological Processes of the Changjiang River -- Lake hydro-morphodynamic Processes of the Changjiang River -- Channel sediment-dynamics along the mid-lower reach of the Changjiang River -- Tidal flat morphodynamics of the Changjiang Estuary -- Changjiang Estuary modern morphodynamic processes -- Estuarine submerged delta modern morphodynamics -- Morphodynamic couplings between river and delta.
    Abstract: This book provides a comprehensive and systematic analysis of the morphodynamic process of the Changjiang River from upstream to estuary in the Anthropocene. As the longest river in China, the Changjiang River has nurtured Chinese civilization with ample natural resources for thousands of years. Evidence highlights that the Changjiang River has experienced intensive human interference and indicated dramatic changes in the Anthropocene, including “no flood in flood season, no dry in dry season” in discharge; “less flood in flood season, more dry in dry season” in sediment; riverbed shifts from accretion to erosion; lakes in the middle-lower reach turn from sediment sink to source; estuarine tidal flat exhibits self-organization characteristics and maintains the current accretion state; estuarine branches that connect to the sea show district morphodynamic patterns; and depocenters of the submerged delta indicate periodic shifts. The book stresses that dam construction upstream, practically the Three Gorges Dam, the world’s largest hydraulic engineering project, has significant influences on the hydrology and geomorphology of the middle-lower reach but has a slight effect on estuarine delta development. The geomorphological structure of the estuarine channel is dominated by local land reclamation, navigation, and dredging. This book clarifies the river-estuary morphodynamics of the Changjiang River and indicates the general features of global mega rivers under human interference as well as their own response mechanisms. This book also exhibits the potential risk of river-estuary deltas in the future, as both material and dynamics are experiencing acceleration adjustment.
    Type of Medium: Online Resource
    Pages: XXI, 358 p. 247 illus., 237 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811637711
    URL: https://doi.org/10.1007/978-981-16-3771-1
    DOI: 10.1007/978-981-16-3771-1
    DDC: 551.48
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    Plitvice Lakes (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Biogeography. ; Sedimentology. ; Geomorphology. ; Water. ; Biogeosciences. ; Sedimentology. ; Geomorphology.
    Description / Table of Contents: Geomorphological and Geological Properties of Plitvice Lakes Area -- Hydrology, Hydrogeology and Hydromorphology of the Plitvice Lakes Area -- Water Chemistry -- Environmental Isotope Studies at the Plitvice Lakes -- Recent Tufa Deposition -- Springs of the Plitvice Lakes.
    Abstract: After providing a historical overview, this book highlights the current state of knowledge, gaps in our knowledge, recent findings and future prospects with regard to the biological, chemical, geological, and geographical specificities of the Plitvice lakes in Croatia. The Plitvice lakes are a unique environment and home to tufa – a type of calcium carbonate deposit that provides a substrate for living organisms. Its formation process has resulted in a vastly diverse environment of lakes, streams and riparian habitats. The Plitvice lakes have, therefore, historically been both an inspiration and a challenge for scientists, nature enthusiasts, artists, etc. Today, the lakes continue to offer an in-situ laboratory for new discoveries in all aspects of freshwater science. As in most habitats, global changes have become an important issue. Since the Plitvice lakes have remained largely untouched by direct human impacts and have a long historical tradition in research, they represent an ideal subject for assessing the effects of global changes in a temperate freshwater system. This book provides an ecological overview of the biogeochemical processes at work in a unique and virtually pristine European freshwater tufa-forming environment.
    Type of Medium: Online Resource
    Pages: VIII, 372 p. 200 illus., 175 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031203787
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-031-20378-7
    DOI: 10.1007/978-3-031-20378-7
    DDC: 551.48
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  • 69
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    Force Majeure in the Hydropower Industry : Concepts and Case Studies (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Water-power. ; Environmental Law. ; Environment. ; Earth sciences. ; Water. ; Hydroenergy. ; Environmental Law. ; Environmental Sciences. ; Earth Sciences.
    Description / Table of Contents: Chapter 1 Introduction -- Chapter 2 Water for energy versus energy for water -- Chapter 3. Energy sectors that use water -- Chapter 4. The context of the development of the World hydropower sector -- Chapter 5. The impact of drought on the hydropower domain -- Chapter 6. Force majeure -- Chapter 7. Sample contractual provisions, which must be contained in a force majeure contract -- Chapter 8. Concrete cases of invocation of force majeure -- Chapter 9. Romania, in a European energy context -- Chapter 10. Settlement of the dispute, in case the force majeure clause is invoked by Hidroelectrica SA -- Chapter 11. Electricity, systemic crises and environmental policies.
    Abstract: This book aims to highlight the particular situation faced by certain hydropower companies by the fact that they cannot fulfil their contracts due to force majeure. The first part of this book will be an analysis of how water is used in electricity production. It is important to point out that all types of energy sources use water, to a different extent, of course, and that its spatial and temporal availability is very important. The focus will be on hydropower, presenting the current situation at the global level, and the effect of reducing the amounts of water in the river system. The second part is based on the presentation of the concept of force majeure and the ways of presenting and drafting it in a contract. Many disputes or the success of a contract depended heavily on the provisions of this article of the contract. Obviously, there are also situations in which the signatory parties abuse or are not protected by these provisions of force majeure. Starting from a few brief examples from the international level, we reach a wide discussion of the situation created in Romania, when the largest supplier of electricity produced on the basis of water terminates several contracts invoking force majeure. The manner in which the opinion of the parties involved is presented to the court is analyzed and presented in detail.
    Type of Medium: Online Resource
    Pages: XI, 156 p. 35 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031274022
    URL: https://doi.org/10.1007/978-3-031-27402-2
    DOI: 10.1007/978-3-031-27402-2
    DDC: 551.48
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    Salt-affected Soils and Marginal Waters : Global Perspectives and Sustainable Management (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Agriculture. ; Pollution. ; Sustainability. ; Environmental management. ; Water. ; Agriculture. ; Pollution. ; Sustainability. ; Environmental Management.
    Description / Table of Contents: Chapter 1. Nature and Origin of Salts, Classification, Area and Distribution of Salt-affected Soils -- Chapter 2. Saline Soils -- Chapter 3. Management and Reclamation of Saline Soils -- Chapter 4. Biodrainage -- Chapter 5. Alkali Soils -- Chapter 6. Reclamation and Management of Alkali Soils for Crop Production -- Chapter 7. Nutrient Management in Salt-affected Soils -- Chapter 8. Irrigation Water: Quality Criteria -- Chapter 9. Irrigation and Salinity Control -- Chapter 10. Wastewaters as Non-conventional Sources of Irrigation -- Chapter 11. Trees and Grasses as Alternate Strategies for Management of Salt-affected Soils -- Chapter 12. Environmental Impact of Reclamation of Salt-affected Soils and Intensive Irrigated Agriculture.
    Abstract: This book presents systematic scientific appraisal, classification, genesis and viable technologies for reclamation and management of salt-affected soils and marginal quality waters across India and several other countries. Nature, solubility and geo-chemical mobility of salts have been provided as basis for the development of alkali and saline soils and groundwaters under specific agro-hydro-ecological regions. Chemical amendment (gypsum) based reclamation technology of alkali soils and related pre and post-reclamation water, nutrient and crop management interventions, including re-sodification issues have been comprehensively addressed. Features and operational guidelines of surface, subsurface, vertical and bio-drainage systems have been thoroughly discussed; likewise, amelioration of irrigation induced saline soils in inland and coastal regions and preventive measures for control of salinity and waterlogging along with environmental trade-offs. Practical approaches for amelioration and judicious use of saline, alkali, high SAR- saline and waste waters have been synthesized for different cropping and agro- forestry systems. Emerging issues on use of industrial by-products as amendments for alkali soils, physiological aspects of salt resistance, anatomical and biochemical mechanism of submergence tolerance, specific ion effects of poor quality waters, crop diversification, groundwater recharge, rejuvenation of tsunami affected coastal soils, safety against occurrence of poisonous gas in tube well pits, paddy straw burning and others have been adequately deliberated upon. Combining scientific principles with field experiences, the book is expected to serve as a useful knowledge base for research workers, teachers and students of soil science, agronomy, plant breeding, forestry, irrigation engineering, extension workers, environmentalists and planners associated with reclamation and management of salt affected soils and waters on sustainable basis in developing and developed countries.
    Type of Medium: Online Resource
    Pages: XXII, 714 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030784355
    URL: https://doi.org/10.1007/978-3-030-78435-5
    DOI: 10.1007/978-3-030-78435-5
    DDC: 551.48
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  • 71
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    Small Water Bodies of the Western Balkans (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Earth sciences. ; Ecology . ; Water. ; Earth Sciences. ; Ecology.
    Description / Table of Contents: Springs as essential water sources for dependent ecosystems in karst -- Small standing-water ecosystems in the transitional temperate climate of the Western Balkans -- Conservation value and habitat diversity of fluvial lakes and gravel pits in river-floodplain systems -- Fountains - overlooked small water bodies in the urban areas -- Temporary ponds in Mediterranean islands: oases of biodiversity -- Riparian springs – challenges from a neglected habitat -- Ecological characteristics and specifics of spring habitats in Bosnia and Herzegovina -- Algae in shallow and small water bodies of Serbia: a frame for species and habitat protection -- Springs and headwater streams in Serbia: the hidden diversity and ecology of aquatic invertebrates. Springs of Southeastern Serbia with a focus on the Vlasina Plateau: different types of challenges for the macroinvertebrate community. Gastropods in small water bodies of the Western Balkans – Endangerments and threats. Importance of small water bodies for diversity of leeches (Hirudinea) of Western Balkan -- Karst springs: isolated ecosystem ecology from the water mite perspective -- Large branchiopods in Small Water bodies: A case study of the Ramsar site „Bardača Wetland“ (NW Republic of Srpska, Bosnia and Herzegovina) -- How important are small lotic habitats of the Western Balkans for local mayflies? -- Fish communities over the Danube wetlands in Serbia and Croatia -- The importance of small water bodies’ conservation for maintaining local amphibian diversity in the Western Balkans -- Human impact induces shifts in trophic composition and diversity of consumer communities in small freshwater ecosystems. Pollution of small lakes and ponds of the Western Balkans - assessment of levels of potentially toxic elements. Conclusions: Small water bodies of the Western Balkans – values and threats. .
    Abstract: The small water bodies such as headwater streams, springs, ditches, small lakes, and ponds are critical to maintaining freshwater biodiversity. This is especially true for Dinaric karst, where they are often the only water bodies present. However, despite their importance, they remain widely overlooked and excluded from government policies like the EU Water Framework Directive. This book includes information on different aspects of these essential but still neglected habitats. This book intends to be of interest to a wide range of audiences, from researchers and conservationists to the public and decision-makers.
    Type of Medium: Online Resource
    Pages: VII, 451 p. 117 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030864781
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-86478-1
    DOI: 10.1007/978-3-030-86478-1
    DDC: 551.48
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    Hydrological Modeling : Hydraulics, Water Resources and Coastal Engineering (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Earth sciences. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Natural disasters. ; Sustainability. ; Water. ; Earth Sciences. ; Environmental Engineering/Biotechnology. ; Natural Hazards. ; Sustainability.
    Description / Table of Contents: Performance improvement of usbr vi stilling basin model for pipe outlet -- Rain water harvesting for the main campus of jaipur national university, jagatpura, Jaipur -- Bio Inspired Genetic Algorithm for Optimal Design of Water Distribution Networks -- Drought assessment using various drought indices: a case study of banaskantha district -- Top surface soil moisture retrieval using c- band synthetic aperture radar over kudremukh grasslands -- Meteorological drought assessment in the bharathapuzha river basin -- Experimental and numerical analysis of mean pressure coefficient on C-shaped building with and without round corner. .
    Abstract: This book carefully considers hydrological models which are essential for predicting floods, droughts, soil moisture estimation, land use change detection, geomorphology and water structures. The book highlights recent advances in the area of hydrological modelling in the Ganga Basin and other internationally important river basins. The impact of climate change on water resources is a global concern. Water resources in many countries are already stressed, and climate change along with burgeoning population, rising standard of living and increasing demand are adding to the stress. Furthermore, river basins are becoming less resilient to climatic vagaries. Fundamental to addressing these issues is hydrological modelling which is covered in this book. Integrated water resources management is vital to ensure water and food security. Integral to the management is groundwater and solute transport, and this book encompasses tools that will be useful to mitigate the adverse consequences of natural disasters.
    Type of Medium: Online Resource
    Pages: X, 526 p. 289 illus., 219 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030813581
    Series Statement: Water Science and Technology Library, 109
    URL: https://doi.org/10.1007/978-3-030-81358-1
    DOI: 10.1007/978-3-030-81358-1
    DDC: 551.48
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  • 73
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    Thermodynamic and Thermophysical Properties of Saline Water : Models, Correlations and Data for Desalination and Relevant Applications (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Pollution. ; Refuse and refuse disposal. ; Water. ; Freshwater and Marine Ecology. ; Environmental Engineering/Biotechnology. ; Pollution. ; Waste Management/Waste Technology.
    Description / Table of Contents: Introduction -- Density -- Heat Capacity -- Entropy -- Latent Heat -- Boiling Point Elevation -- Vapor Pressure -- Viscosity -- Thermal Conductivity -- Activity Coefficient -- Osmotic Coefficient -- Surface Tension -- Electrical Conductivity -- Thermal Expansivity -- List of Nomenclature.
    Abstract: This book accommodates the existing correlations, data, and methods for thermodynamic and thermophysical properties of saline water, including multiple components at a wide range of salinity (reaching around 200 g/kg), temperature, and pressure. The correlations of each property are plotted against existing experimental data to judge the comparative accuracy of each within a given specific range of salinity, temperature, and pressure. An assessment to recommend some correlations is also conducted. New correlations for some properties are also proposed. This book helps to provide the saline water properties as needed for engineers, designers, and research for different areas, including desalination and water treatment. All the analytical analysis, thermodynamic analysis, and design models of the desalination technologies depend on saline water properties. As scientists and researchers working on different desalination technologies, the authors found it difficult to find all saline water properties in one source, including multicomponent and binary salty solutions, under different conditions (salinity, temperature, and pressure). Therefore, the authors introduce this book to fill the gap in the open literature. This book compiles the thermodynamic and thermophysical properties of saline water, involving thermodynamic approaches, multicomponent models, and simple correlations and data, comparison between the correlations of properties in figures, recommendation of the most accurate correlations and methods, and the used codes to estimate these correlations and methods. It is expected that this book to be a principal source for all interests in desalination and water treatment subjects.
    Type of Medium: Online Resource
    Pages: XIX, 325 p. 39 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031351938
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-031-35193-8
    DOI: 10.1007/978-3-031-35193-8
    DDC: 551.48
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    Advances in Water Resource Planning and Sustainability (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Sustainability. ; Power resources. ; Water. ; Sustainability. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Remote sensing in water resource monitoring A comprehensive review on monitoring the quality and quantity of the water resources using remote sensing applications -- Assessment of Vegetation Dynamics of Paddy Crop using”TIMESAT” and Remote Sensing & GIS Techniques in Command Areas -- Assessment of River Water Dynamics and Optically Active Water Quality Parameters over Punjab, Based on Cloud Computing -- Analysis of land use/land coverchange and its impact on 2021 Chiplun Flood, Maharashtra, India -- Flood Disaster Hazards: A State-of-the-Art Review of Causes, Impacts, and Monitoring -- Impact of Land Use Systems and Climate Change on Water Resources: Indian Perspectives -- Seawater Intrusion Mapping along Penneru River Basin Area, SPS Nellore District, Andhra Pradesh – A Case Study -- Flood detection and Flood Mapping using Multi-temporal Synthetic Aperture Radar and Optical data -- Climate Change and Its impact -- Impact of land use changes on water resource: Assessment through Remote Sensing -- Vulnerability to Climate Change in different sectors of Lugvalley, Kullu district of Himachal Pradesh -- Assessment of Groundwater level and fluctuations using Geospatial Techniques in Nambiyar Watershed, South India -- River Flood Monitoring and Management: A Review -- Evaluation of Groundwater Quality for Irrigation-A Case Study of West Godavari District of Andhra Pradesh -- Interactions of Hydrological Parameters and the Effects on Perennial Riverbanks of the Indo-Bhutan Region in Eastern Himalaya -- Ecosystem Services in the Riverine Landscapes -- Evaluation of Morphometric Analysis of Kharag River basin, Odisha using Geospatial Techniques.
    Abstract: Sustainable water resources planning deals with the interface of water resources science and the needs of human populations. It highlights works that addresses practical methods and basic research in, for example: quantity and quality management of groundwater and surface water resources; sustainability of water resources and water availability; water use and reuse including managed aquifer recharge and storage; geopolitical and socio-economic aspects of water resource management; water development and human activity impacts on ecological systems and human health, including, for instance, agricultural and climatic impacts, subsurface waste storage and injection, geothermal energy development and subsurface energy storage. This book provides up-to-date systematic and scientific analyses of such water problems and suggests sustainable measures to overcome them through effective surface and sub-surface water resource management. It is immensely valuable to students, researchers, water resource managers, hydrologists and all those who are engaged or interested in any aspect of river water conservation and management of water resources.
    Type of Medium: Online Resource
    Pages: VI, 322 p. 128 illus., 120 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936601
    Series Statement: Advances in Geographical and Environmental Sciences,
    URL: https://doi.org/10.1007/978-981-99-3660-1
    DOI: 10.1007/978-981-99-3660-1
    DDC: 551.48
    Language: English
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  • 75
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    Online Resource
    The Irrigation Future of India : Development, Resource and Policy (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Agriculture Economic aspects. ; Economic geography. ; Water. ; Agricultural Economics. ; Economic Geography.
    Description / Table of Contents: Chapter 1: The Irrigation Future of India: Overview, Synthesis and Way Forward -- Chapter 2: Indian Irrigation Sector: Overall Physical Setting and Institutional Context -- Chapter 3: Diagnosing Water Crisis in India: Results from a Case Study of Maharashtra State -- Chapter 4: Temporal Trends and Regional Patterns in Development of Irrigation in India -- Chapter 5: Is the Impact of Irrigation in Agricultural Output Declining in India?: A Disaggregated Analysis -- Chapter 6: Groundwater Irrigation in India: Development, Overexploitation and Sustainability -- Chapter 7: Losers and Gainers of Groundwater Irrigation Development: Results from a Study of Peninsular India -- Chapter 8: Poverty Reducing Role of Groundwater Irrigation: Evidence from a Cross-Sectional Analysis -- Chapter 9: Financial Performance of India’s Irrigation Sector: Past, Present and Future -- Chapter 10: Turnaround of Financial Recovery in Irrigation Sector: A Case Study of Maharashtra State -- Chapter 11: Tank Irrigation in India: Why is it Declining? -- Chapter 12: Performance of Tank Irrigation in India: A Case Study of Andhra Pradesh -- Chapter 13: Effects of Urbanisation on Tank Irrigation: A Case Study of Tamil Nadu -- Chapter 14: Innovative Farm Practice and Water Use Efficiency: A Study of the System of Rice Intensification under Different Irrigated Settings in South India -- Chapter 15: Extent and Scope for the Adoption of Water Saving Technologies: An Analysis of Drip and Sprinkler Irrigation in India -- Chapter 16: Economic Impact of Drip Irrigation: An Empirical Analysis with Farm Level Data -- Chapter 17: Summary and Policy Pointers.
    Abstract: This book aims to bring forth and address the major issues confronting the irrigation sector of India and also to suggest policy pointers to sustain it. As the policy and reform canvas is large for a huge and diverse country, this book has particular focus on the most important and immediate issues and future options. The chapters not only focus on new research, in-depth analysis and technical details, but also provide a balanced review of the state of irrigation sector and comprehensive presentation of major issues, challenges and future options. With the presentation of in-depth analysis and synthesis of available knowledge, the work can act as a handbook for major irrigation water issues, actual policy changes, and potential reform that could turnaround the sector. Given the temporal and spatial data analysis of the irrigation sector, this book will be effective and useful as a research and teaching tool to students and researchers both in India and globally. Besides its professional audience within the academic, research and policy community, the non-technical format of the book will appeal to a general audience in the media, policy, and donor circles.
    Type of Medium: Online Resource
    Pages: XVII, 389 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030896133
    Series Statement: Global Issues in Water Policy, 29
    URL: https://doi.org/10.1007/978-3-030-89613-3
    DOI: 10.1007/978-3-030-89613-3
    DDC: 551.48
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  • 76
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    Type-Based Flood Statistics : An Interlink Between Stochastic and Deterministic Flood Hydrology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Statistics . ; Natural disasters. ; Geographic information systems. ; Water. ; Statistics. ; Natural Hazards. ; Geographical Information System.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Characterisation of Flood Events – Event Separation and Flood Typology -- Chapter 3. Univariate Flood-Type-specific Flood Statistics -- Chapter 4. Multivariate Flood-Type specific Flood Statistics under consideration of tributary impacts -- Chapter 5. Regionalisation of Flood-type specific distributions -- Chapter 6. Main applications of the new methodology -- Chapter 7. Summary and outlook -- Appendix.
    Abstract: This book summarises for the first time all relevant methodologies for type-based flood statistics, introduces the basis of flood typology and makes them accessible to the user. Flood types improve the understanding of the flood-generating processes and characterise the flood event in terms of its features such as peak, volume and hydrograph shape. In addition, they can also significantly expand the information used in flood statistics and add valuable flood characteristics to the determination of design floods, especially the determination of flood scenarios relevant for reservoir management. A detailed framework with all aspects of point and spatial statistics as well as regionalisation is presented, and examples illustrate the benefit of the proposed methodology. The target audience is both users in associations and engineering offices, as type-based statistics are increasingly becoming part of the specifications, and researchers, as this is a current field of research.
    Type of Medium: Online Resource
    Pages: XVIII, 275 p. 114 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031327117
    Series Statement: Water Science and Technology Library, 124
    URL: https://doi.org/10.1007/978-3-031-32711-7
    DOI: 10.1007/978-3-031-32711-7
    DDC: 551.48
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    Climate Change in Sustainable Water Resources Management (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Environmental management. ; Sustainability. ; Water. ; Environmental Management. ; Sustainability.
    Description / Table of Contents: Overview of climate change in water resources management studies -- Basic concepts -- Climate Change Drivers -- The Effect of Climate Change on Water Resources -- Review on IPCC reports -- Introduction to Key Features of Climate Models -- Downscaling Methods -- Hydrological models -- Mitigation and Adaptation Measures -- Case Studies Around the World.
    Abstract: This book provides a comprehensive approach to all aspects of water-related subjects affected by climate change that expand readers' attitudes toward future of the management strategies and improve management plans. It summarizes climate change scenarios, models, downscaling methods, and how to select the appropriate method. It also introduces practical steps in assessing climate change impacts on water issues through introducing hydrological models and climate change data applications in hydrologic analysis. The book caters to specialist readers who are interested in analyzing climate change effects on water resources, and related issues can gain a profound understanding of the practical concepts and step-by-step analysis, which is enriched with real case studies all around the world. Moreover, readers will be familiar with potential mitigation and adaptation measures in sustainable water engineering, considering the results of hydrologic modeling.
    Type of Medium: Online Resource
    Pages: VIII, 415 p. 80 illus., 65 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811918988
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-981-19-1898-8
    DOI: 10.1007/978-981-19-1898-8
    DDC: 551.48
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  • 78
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    Wastewater from Olive Oil Production : Environmental Impacts, Treatment and Valorisation (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Chemistry, Technical. ; Biology. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Industrial Chemistry. ; Biological Sciences. ; Waste Management/Waste Technology.
    Description / Table of Contents: Chapter 1: Valorization of olive tree by-products by co-composting -- Chapter 2: Olive oil mill wastewaters treatment methods -- Chapter 3: Olive mill wastewater: Treatment and valorization -- Chapter 4: Valuable materials from OMW -- Chapter 5: Study the value of olive mill wastewater and their impact on the receiving environment -- Chapter 6: A state-of-art review on the use of olive-oil mill wastewater for human purposes -- Chapter 7: Olive mill waste water bioactive molecules: applications in animal farming -- Chapter 8: Physicochemical characterization and estimation of the pollution degree of olive oil mill wastewaters from the cold extraction system and the traditional system -- Chapter 9: Characterization of top soils subjected to poorly controlled olive oil production wastewater and its effect on litter decomposition -- Chapter 10: Open ponds for effluent storage, a pertinent issue to olive mill wastewater (OMW) management in a circular economy context: Benefits and environmental impact -- Chapter 11: Olive mill wastewaters (OMWWs) a natural tank gorged with bioactive molecules -- Chapter 12: Management of olive oil mill wastewater in Morocco: Production, impacts, and treatment -- Chapter 13: Turkey’s olive mill wastewater (OMWW) problems and some suggestions -- Chapter 14: Future trends in olive industry waste management: A literature review.
    Abstract: This book summarizes the recent research development concerning olive oil wastewater management: characterization, environmental impact, recovery and treatment. The book combines different chapters on the management of olive oil rejects using simple techniques with low investment and operating costs. The main focus of the book is: - Diagnosis, impacts of olive oil waste, and regulations - The valorization of the margins and the olive waste - Wastewater treatment and recovery - Evaluation of investments and operating costs of treatment techniques - Shaped by experience, the authors present their view and approach to each focus area of managing liquid and solid waste produced by crushing units.
    Type of Medium: Online Resource
    Pages: XV, 297 p. 30 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031234491
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-031-23449-1
    DOI: 10.1007/978-3-031-23449-1
    DDC: 551.48
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    Water Challenges in Rural and Urban Sub-Saharan Africa and their Management (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Water. ; Hydrology. ; Sustainability. ; Environment. ; Food security. ; Earth sciences. ; Geography. ; Water. ; Sustainability. ; Environmental Sciences. ; Food Security. ; Earth and Environmental Sciences.
    Description / Table of Contents: Chapter 1. Introduction to Water Resources of Sub-Saharan Africa -- Chapter 2: Water Challenges in Rural Sub-Saharan Africa -- Chapter 3: Water Challenges in Urban Sub-Saharan Africa -- Chapter 4. Management of Water Challenges in Sub-Saharan Africa -- Chapter 5. Progress towards attaining SDG target on universal access to clean water in Sub-Saharan Africa -- Chapter 6: Recommendations to Improve Management of Water Challenges in Sub-Saharan Africa -- Conclusions.
    Abstract: Sub-Saharan Africa grapples with many public health issues such as food insecurity, increased prevalence of infectious diseases, limited access to clean water supply, poor nutrition and lack of improved health services for its populace (IMF, 2021). Of all these challenges, the inaccessibility of clean water supply for both the rural and urban populace is the most pressing challenge, which has been exacerbated by extensive pollution and climate change crises. The issue of water access and supply affects both rural and urban populations. At rural areas water is accessed in yard taps and in arid regions through water kiosks managed by private owners. Among the urban poor, water access is compromised by poor supply infrastructure especially among informal settlers and risks such as contamination during the supply chain are imminent This book therefore seeks to close this knowledge gap by 1) generating a water resources inventory for Sub-Saharan Africa region, 2) exploring the water crises in both its urban and rural settings, 3) understanding the causatives of the crises and 4) suggesting viable solutions to manage the water challenges using named case studies. The aim is to improve understanding on the region’s water problems and advise scholars and policymakers on priority research areas and action plans to better water management for sustainable development. .
    Type of Medium: Online Resource
    Pages: IX, 112 p. 18 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031262715
    Series Statement: SpringerBriefs in Water Science and Technology,
    URL: https://doi.org/10.1007/978-3-031-26271-5
    DOI: 10.1007/978-3-031-26271-5
    DDC: 551.48
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  • 80
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    Advanced Treatment Technologies for Fluoride Removal in Water : Water Purification (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Environmental management. ; Environmental health. ; Sustainability. ; Water. ; Pollution. ; Environmental Management. ; Environmental Health. ; Sustainability.
    Description / Table of Contents: Introduction -- Part-I: Remediation and management strategies -- Chapter 1: Fluoride contamination in water and its management -- Chapter 2: Fluoride pollution control techniques and principles -- Chapter 3: Hybrid phytoremediation of fluoride and its remediation strategies -- Part-II: Fluoride removal treatments -- Chapter 4: Physicochemical and biological methods for the removal of fluoride -- Chapter 5: Removal of fluoride from water through iron-based adsorbents -- Chapter 6: Removal of fluoride from water through fly-ash beds -- Chapter 7: Fluoride removal from industrial wastewater using filtration and chemical precipitation -- Part-III: Fluoride effect on human health -- Chapter 8: Fluoride contamination, health problems and remediation, methods in water: A comprehensive review -- Chapter 9: Effect of fluoride pollution on the living beings with an emphasis on human health hazard -- Chapter 10: Nutritional status and dental fluorosis among humans in communities with different water source fluoride concentrations -- Part-IV: Status, government policy, and environmental regulating bodies -- Chapter 11: Global perspective scenario: fluoride contamination in water -- Chapter 12: Government rules and public involvement of wastewater discharge containing fluoride -- Chapter 13: Future frameworks for fluoride and algorithms for environmental systems -- Part-V: Concluding remarks along with recommendation.
    Abstract: This book presents an overview of the techniques available today for the removal of fluoride contamination/pollutants/species from water. Also covered are traditionally applied techniques for the removal of fluoride pollutants/species, including oxidation, coagulation-flocculation, and membrane techniques. Recently, progress has been made on the utility of various nanoparticles for the extraction of contaminants from water. Fluoride contamination is affecting water resources quality worldwide as a result of human activities, such as mining and pesticide use. Due to the high risk of fluoride exposure, specific water treatment processes are required to meet more severe water quality standards. A better understanding of currently available processes is necessary to develop economical, efficient, and effective methods for fluoride removal. Fluoride can either be coated, adsorbed using a wide range of both mineral and organic constituents or can be directly rejected by membrane processes, such as reverse osmosis and nanofiltration. Recent developments of submerged hybrid membrane systems, such as membrane bioreactors in wastewater treatment, provide alternative technologies for fluoride treatment. .
    Type of Medium: Online Resource
    Pages: XVII, 364 p. 56 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031388453
    Series Statement: Water Science and Technology Library, 125
    URL: https://doi.org/10.1007/978-3-031-38845-3
    DOI: 10.1007/978-3-031-38845-3
    DDC: 551.48
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    Surface and Groundwater Resources Development and Management in Semi-arid Region : Strategies and Solutions for Sustainable Water Management (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Geology. ; Geotechnical engineering. ; Sustainability. ; Water. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences. ; Sustainability.
    Description / Table of Contents: Chapter 1. Evapotranspiration importance in water resources management through cutting-edge approaches of Remote sensing and machine learning algorithms (Ali Raza) -- Chapter 2. Application of Remote Sensing and GIS for Morphometric Analysis: A Case Study of Burhanpur Watershed (Abhishek Patel) -- Chapter 3. A GIS-based DRASTIC approach for Aquifer vulnerability assessment: Study conducted in the Municipal Corporation region of Ranchi, Jharkhand (Shivam Saw) -- Chapter 4. Evaluation of Infiltration Models in an Agricultural Catchment Using Guelph Permeameter in Mysuru District (Harshith Y) -- Chapter 5. Investigation of trends and variability associated with the SPI and SPEI as a drought prediction tools in Gujarat regions, India (Paras Hirapara) -- Chapter 6. Fluoride mobilization and provenance identification in semi-arid conditions: A Hydrochemical and Isotopic approach (Abhinav Patel) -- Chapter 7. A comparative study of different inverse groundwater models for aquifer parameter estimation (Sharad Patel) -- Chapter 8. Water resources and irrigation management using GIS and Remote Sensing techniques: Case of Multan district (Pakistan) (Ali Raza).
    Abstract: This book explains the challenges for efficient sustainable surface and groundwater development and management with the focus on India and other countries, providing a stable output presentation by using machine learning data mining methods, and modeling. It is a combination of machine learning, modeling, google earth engine, climate data modeling, remote sensing and GIS techniques, surface water modeling, AHP modeling, groundwater quality analysis, aquifer mapping, land use and land cover analysis, forecasting of water and rainfall and so on, its use to sustainable development, planning, and management of groundwater purposes in India and other countries. The main purpose of this book will develop better outlines for the development of surface and groundwater and management in the semi-arid region climate, which supports the Sustainable Development Goals (SDGs) in India, especially on sustainable surface water and groundwater resources management. This book provides a multidisciplinary overview for the faculty members, administrators scientists, policymakers, social science, and professionals involved in the various aspects of sustainable groundwater development, planning, and management.
    Type of Medium: Online Resource
    Pages: IX, 427 p. 172 illus., 161 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031293948
    Series Statement: Springer Hydrogeology,
    URL: https://doi.org/10.1007/978-3-031-29394-8
    DOI: 10.1007/978-3-031-29394-8
    DDC: 551.48
    Language: English
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    Ecological Quality Status of Marine Environment : Metal- Sulfide Models; Significance, Mobility, Mechanisms and Impacts (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Environmental chemistry. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Environmental Chemistry. ; Waste Management/Waste Technology.
    Description / Table of Contents: Chapter I; Introduction to the Significant Impact of AVS on Controlling the Metal Toxicity Regarding Sulfur Cycle -- Chapter II; Chemistry of Sulfur Components and Factors Controlling AVS Concentrations in Marine Environment -- Chapter III; Experimental Approach to Sampling, Storage, Extraction, Determination of AVS-SEM -- Chapter IV; AVS-SEM MODELS -- Chapter V; A Review and an Outlook "AVS- SEM" Studies in Egypt Compared to Aquatic Environment around the World -- Chapter VI; Update, Conclusions, Recommendations, Future Perspective and Challenges.
    Abstract: The goal of this one-of-a-kind book was to provide a critical and in-depth understanding of various AVS-SEM models as predictors for assessing the ecological impact of heavy metals (particularly dibasic cations; Zn, Cd, Ni, Cu, and Pb) on aquatic environments, including the theories underlying these models, descriptive equations, modes of action, methodology, efficiency, applicability, and statistical approaches, as well as comparison with other pollution assessment techniques in the aquatic environments. Metals in interstitial water can be reduced in sediments that co-precipitate with iron (Fe) and manganese (Mn) in FeS or MnS minerals, as well as replace them. This book outlines a system that can be used to track heavy metal contamination in countries with coastal regions that extend over water bodies that are subjected to pollution sources, such as the Mediterranean Basin countries. Moreover, this book will be of great interest to academics, professionals, practitioners, post-graduate students (M.Sc. and Ph.D.), and undergraduates because it gives a clear overview of heavy metal assessment for people interested in environmental studies focusing on the marine environment. It also provides decision-makers with a realistic perspective of the environmental file, allowing them to address environmental issues and directing stockholders to safer locations for environmental activity. From a future perspective, management is advised to overcome the difficulties within that technique, such as accurate handling procedures and different approaches to sampling onshore and offshore. Sequential leaching strategies, especially geochemical fractionation analysis, and knowledge of the interactions and significance of AVS in the marine sector, especially toxicity tests (bioassay) are recommended.
    Type of Medium: Online Resource
    Pages: XXI, 103 p. 41 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031292033
    Series Statement: Earth and Environmental Sciences Library,
    URL: https://doi.org/10.1007/978-3-031-29203-3
    DOI: 10.1007/978-3-031-29203-3
    DDC: 551.48
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    Resilience in the English Small-Scale Fishery : Small Fry but Big Issue (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Animal culture. ; Water. ; Animal Science.
    Description / Table of Contents: Chapter 1 : Introduction -- Chapter 2: Interpretive Framework and Methodology -- Chapter 3: The English Inshore Fleet -- Chapter 4: Perceptions of Vulnerability in the English SSF -- Chapter 5: Strategies of Resilience in the English SSF -- Chapter 6: Discussion of the Resilience Strategies -- Chapter 7: Conclusion.
    Abstract: This book is a contribution to our understanding of the worrying situation of small-scale fisheries (SSF) which face marginalisation in most coastal countries. The authors explain why SSF are so pressured; how there has been a powerful backlash against this marginalisation during the last 30 years; what are the main ideational currents supporting this backlash; and what is the enduring value of SSF that justifies that support. The authors discuss the major contemporary interpretations of SSF; the challenges facing SSF globally and in England; and SSF’s coping strategies in response to those challenges through the framework of resilience theory. In an innovative analysis, the authors show how there are three kinds of resilience: passive resilience (where fishers are resigned to their adverse fate), adaptive resilience (where fishers make the best use of the opportunities that are available to them), and transformative resilience (where fishers attempt to change the system that faces them). The authors draw on an extensive range of interview data to provide rich insights into the world of SSF, and they discuss a variety of proposals for improving their conditions. The book will appeal to the growing academic and public community that is following with increasing concern the debate about the future of SFF, and to the environmental movement which has committed itself to support SSF as a greener form of fishing than the large-scale industrial sector.
    Type of Medium: Online Resource
    Pages: XII, 186 p. 2 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030542450
    URL: https://doi.org/10.1007/978-3-030-54245-0
    DOI: 10.1007/978-3-030-54245-0
    DDC: 551.48
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    Indigenous and Local Water Knowledge, Values and Practices (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Human ecology Study and teaching. ; Environmental protection. ; Civil engineering. ; Sustainability. ; Environmental management. ; Indigenous peoples Religion. ; Water. ; Environmental Studies. ; Soil and Water Protection. ; Sustainability. ; Environmental Management. ; Indigenous Religion.
    Description / Table of Contents: Chapter 1. Exploring Indigenous Water Knowledge, Values and Practices: Insights and Examples -- Chapter 2. A political-economic analysis of water, indigeneity, and capitalism in the face of climate change -- Chapter 3. Water Symbolism in Hindu Culture -- Chapter 4. Ways of Water Management in Islam: Potential Insights for Future Water Governance -- Chapter 5. Water and Shintoism: Exploring the link between spirituality and water values in Japan -- Chapter 6.Muslim Peoples and the Challenges of Water Security: A Socio-Anthropological Analysis -- Chapter 7.Indigenous water knowledge: Religious values and cultural practices -- Chapter 8.Bringing Back the Wisdom: Tradition in Urban Water Management -- Chapter 9. Interactions between Changing Climates and Land Uses: The Case of Urmia Lake, Iran -- Chapter 10. Indigenous water governance systems in a post-colonial state: Insights from Zimbabwe -- Chapter 11. Benefits of reviving indigenous water conservation practices for drought resilience in red and laterite zones of West Bengal, India -- Chapter 12. Local Knowledge on Water Use and Water-related Ecosystem Services in Lowland, Midland, and Upland Villages in Mindanao, Philippines -- Chapter 13. Indigenous knowledge, practices, and transformation of drinking water management system: Evidence from Munda community of Bangladesh -- Chapter 14.The cultural approach for community-based conservation of river basins: a case study of the Basin School Network, Taiwan -- Chapter 15. Indigenous knowledge and conservation practices for sustainable water management in lateritic Southwest Bengal, India -- Chapter 16. Importance of women’s indigenous knowledge of water conservation and management in Sri Lanka -- Chapter 17. Role of ponds as a local practice in mitigating salinity intrusion threats at coastal aquifer: a case study from Sundarban Biosphere Reserve, India -- Chapter 18. The water cult and conservation in India.-Chapter 19.Concluding reflections on the indigenous and local water knowledge, values, and practices, and lessons learned.
    Abstract: This book provides a knowledge base of the existing indigenous and local water knowledge, values, and practices, and how this water knowledge can be mainstreamed into the decision-making process. The book not only demonstrates the perks of using indigenous knowledge but also illustrates the barriers and gaps that should be considered while planning for mainstreaming traditional knowledge and values at a local scale. The chapters incorporate case studies from various parts of the world demonstrating how indigenous, and religious and cultural values of water have translated into water use and conservation behavior among indigenous people ensuring resource sustainability over a long period of time. There has been global attention towards combining indigenous and local knowledge with new information and innovation to attain future water security. In this regard, this book is timely, relevant, and significant as it is the first attempt, as per the best of our knowledge, to publish a book that solely addresses indigenous and local knowledge, values, and practices regarding water management, quality monitoring, use, and conservation. With increasing emphasis on the inclusion of indigenous and local knowledge into natural resource governance and conservation by international agencies like the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES), the proposed book will significantly contribute to the existing knowledge base and demonstrate the importance of mainstreaming indigenous water knowledge and practices into water governance and decision making. The UN SDGs, recognizing the significance of indigenous knowledge systems, emphasized its inclusion in most aspects and principles of SDGs. Apart from direct links with SDGs like zero hunger (SDG 2), no poverty (SDG 1), and climate action (SDG 13), indigenous and local knowledge system is considered to be directly connected to clean water and sanitation (SDG 6). The book will be useful to researchers and students in the field of indigenous knowledge and education, water governance, community-level planning, and water sustainability. The book can be referred to for postgraduate courses and beyond, as well as policymakers, conservationists, non-governmental organizations, development practitioners, and local government officials. .
    Type of Medium: Online Resource
    Pages: XI, 326 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811994067
    URL: https://doi.org/10.1007/978-981-19-9406-7
    DOI: 10.1007/978-981-19-9406-7
    DDC: 551.48
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    The Risk of Water Conflicts in Aotearoa-New Zealand : Emergence and Intensification (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental Law. ; Sustainability. ; Environmental management. ; Peace. ; Water. ; Environmental Law. ; Sustainability. ; Environmental Management. ; Peace and Conflict Studies.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Revisiting Abundance Theory -- Chapter 3. Water Abundance and Water Incompatibilities in New Zealand -- Chapter 4. Research Design -- Chapter 5. Glenorchy -- Chapter 6. Ashburton -- Chapter 7. Analysis -- Chapter 8. Conflict Intentionality Classification -- Chapter 9. Research Intersections and Limitations -- Chapter 10. Conclusions.
    Abstract: This book focuses on water disputes in New Zealand: a country where such conflicts are assumed to be non-existing. Rarely are water disputes examined in areas where water resources abound, and where the political framework that governs their access and use is strong. Environmental security literature has devoted a significant amount of attention to the nexus between resource abundance and conflict. Important research has assessed this relationship by focusing on non-renewable resource wealth as a causal determinant of conflict, but little is known about the conditions that influence the emergence and intensification of conflict in water abundant environments. By most accounts, New Zealand is one of the most water-rich countries in the world. Even though violent conflict over water does not normally materialize in New Zealand, conflicts and incompatible claims motivated by water bottling, the growth of some types of agriculture, tourism, and water treatment strategies, continue to surface. Little, however, is known about how and why these conflicts emerge and intensify in a country such as New Zealand. To address this lacuna, this project asks the following research question: How and why does the commercialization of freshwater influence the emergence and intensification of hydropolitical conflict in New Zealand? This study presents two central arguments. First, that the introduction of a commercial enterprise motivates the emergence of hydropolitical conflict intentionality if the enterprise is incompatible with the interests of local communities. And second, hydropolitical conflict risk intensifies in accordance with the level of trust that communities pose upon the approval and appeals process that supports a commercial operation. To test these arguments, this study examines the effects of water bottling and water chlorination on the towns of Ashburton (Canterbury) and Glenorchy (Otago), by employing a tripartite analysis comprised, first, of a conflict intentionality and engagement assessment, second, of a comparative case study analysis, and third, of a conflict intentionality classification. The data suggests that hydropolitical conflict risk is low when communities trust the approval and appeals process behind any given commercial operation. Water-based conflict risk however is likely to escalate when local communities lose trust in the above processes and the institutions that administer them.
    Type of Medium: Online Resource
    Pages: XXI, 125 p. 15 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031066603
    URL: https://doi.org/10.1007/978-3-031-06660-3
    DOI: 10.1007/978-3-031-06660-3
    DDC: 551.48
    Language: English
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    Impacts of Urbanization on Hydrological Systems in India (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental management. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Refuse and refuse disposal. ; Water. ; Environmental Management. ; Environmental Engineering/Biotechnology. ; Waste Management/Waste Technology.
    Description / Table of Contents: Chapter1. GIS-based Multi-Criteria Decision Analysis for Identifying Rainwater Harvesting Structures Sites in a Semi-Arid River Basin -- Chapter2. Hydrochemical Investigation and Water Quality Mapping in and around Pallikarnai Marsh Land Area in Chennai, India -- Chapter3. Catchment Scale Modeling of Land Use and Land Cover Dynamics -- Chapter4. Urban Floods: A Case Study of Patna Floods 2019, Natural or Anthropogenic?- Chapter5. Flood Susceptibility Zonation using Dempster-Shafer Evidential Belief Function (EBF) Method in Chalakudy Taluk, Kerala, India -- Chapter6. Impact of Urbanization on Ganga River Basin: An Overview in the Context of Natural Surface Water Resources -- Chapter7. Urban Water Scarcity: A Global Challenge and Impending Solutions -- Chapter8. Groundwater Scarcity in Urban Areas is a Major Issue - Case Studies from West Bengal -- Chapter9. Impact of Urbanization and River Morphology on Groundwater System in Patna Urban Area, Bihar, India -- Chapter10. Aquifer Storage and Recovery: Key Issues and Feasibility -- Chapter11. Temporal Prediction of Groundwater Levels: A Gap in Generalization -- Chapter12. Suitability of Groundwater for Drinking and Agricultural Use in Patna District, Bihar, India -- Chapter13. Groundwater Potential Assessment using GIS-based Weighted Linear Combination Technique: A Case Study of Hard Rock Terrain around Bhopal, India -- Chapter14. The Effect of Urbanization on Groundwater Quality and Hydrochemical Characteristics in Ennore Coastal Aquifers of Chennai, South India -- Chapter15. Groundwater Contamination in Parts of Northwestern Hyderabad- A Hydrogeochemical and Geospatial Approach -- Chapter16. Spatio-Temporal Dynamics of Groundwater Recharge in Dras Sub-Basin of Upper Indus River Basin, Western Himalayas -- Chapter17. Impact of Urbanization on Groundwater in Changing Climatic Scenario: A Case Study.
    Abstract: This book documents the various impacts of urbanization on hydrological systems and water resources. The first half of the book is focused on urbanization and surface waters, starting with the status of hydrological systems in the urban areas, i.e. the catchment characteristics and changes in rainfall dynamics. The most pronounced hydrological problems in cities are changes in runoff due to precipitation. Recently, rain events have been less frequent but more intense, sometimes leading to flash floods. Though the substantial increase in runoff causes floods in the urbanized area, it may be attributed to the reduction of infiltration due to construction of roads. This, in turn, results in groundwater decline and depletion. The second half of the book covers the impact of urbanization on groundwater, which starts with hindered or significantly reduced recharge taking place due to altered urban surfaces. The limited groundwater resources are over-exploited by the urban population, leading to water scarcity and depletion. Groundwater gets polluted due to solid waste dumping sites or by wastewaters discharged by industries. The book will be useful for researchers, educators, municipal/city authorities, government officials, and NGOs.
    Type of Medium: Online Resource
    Pages: XVI, 347 p. 160 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031216183
    URL: https://doi.org/10.1007/978-3-031-21618-3
    DOI: 10.1007/978-3-031-21618-3
    DDC: 551.48
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    Satellite Remote Sensing of Terrestrial Hydrology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environment. ; Environmental monitoring. ; Climatology. ; Earth sciences. ; Environmental geography. ; Water. ; Environmental Sciences. ; Environmental Monitoring. ; Climate Sciences. ; Earth Sciences. ; Integrated Geography.
    Description / Table of Contents: Part 1 -- Chapter 1 Introduction -- Chapter 2 Global water sytems -- Part 2 -- Chapter 3 Optical Remote Sensing Systems -- Chapter 4 Satellite Geodetic Missions -- Part 3 -- Chapter 5 GEE Chapter -- Part 4 -- Chapter 6 Remote Sensing of Freshwater Habitats -- Chapter 7 Remot esensing of vegetation changes -- Part 5 -- Chapter 8 groundwater from space -- Part 6 -- Chapter 9 Impacts of Climate Change on Hydrological Cycle -- Chapter 10 Drought metrics and Indicators -- Part 7 -- Chapter 11 Hydrolological variability -- Part 8 -- Chapter 12 Statistical methods in hydrology -- Part 9 -- Chapter 13 SA_JoH -- Part 10 -- Chapter 14 JoH_Regional -- Part 11 -- Chapter 15 STOTEN -- Chapter 16 Climatic Change -- Part 12 -- Chapter 17 Flinders -- Chapter 18 Mitchell -- Part 13 -- Chapter 19 Brazil drought -- Chapter 20 LCB STOTEN -- Appendix.
    Abstract: This book highlights several opportunities that exist in satellite remote sensing of large-scale terrestrial hydrology. It lays bare the novel concept of remote sensing hydrology and demonstrates key applications of advance satellite technology and new methods in advancing our fundamental understanding of environmental systems. This includes, using state-of-the-art satellite hydrology missions like the Gravity Recovery and Climate Experiment and other multi-mission satellite systems as important tools that underpin water resources planning and accounting. This book discusses and demonstrates how the efficacy, simplicity, and sophistication in novel computing platforms for big earth observation data can help facilitate environmental monitoring and improve contemporary understanding of climate change impacts on freshwater resources. It also provides opportunities for practitioners and relevant government agencies to leverage satellite-based information in a transdisciplinary context to address several environmental issues affecting society. This book provides a general framework and highlights methods to help improve our understanding of hydrological processes and impact analysis from extreme events (e.g., droughts, floods) and climate change.
    Type of Medium: Online Resource
    Pages: XXI, 688 p. 213 illus., 201 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030995775
    URL: https://doi.org/10.1007/978-3-030-99577-5
    DOI: 10.1007/978-3-030-99577-5
    DDC: 551.48
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    Water Security Under Climate Change (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Water. ; Hydrology. ; Bioclimatology. ; Financial risk management. ; Sustainability. ; Natural disasters. ; Water. ; Climate Change Ecology. ; Risk Management. ; Sustainability. ; Natural Hazards.
    Description / Table of Contents: Ensuring Water Security under Climate Change -- Water Security in the Face of Climate Change: Singapore’s Way -- Consequences of Declining Resources on Water Services: The Risks If We Do Not React! -- Resilience through Systems Thinking for Water Infrastructure -- Water Security and Climate Change: Hydropower Reservoir Greenhouse Gas Emissions -- Climate Change and its Implications for Irrigation, Drainage and Flood Management -- Designing Research to Catalyse Climate Action -- Water Resilient Places—Developing a Policy Framework for Surface Water Management and Blue-Green Infrastructure -- Supporting Evidence-based Water and Climate Change Policy in Scotland through Innovation and Expert Knowledge: The Centre of Expertise for Waters (CREW) -- Building A Resilient and Sustainable Water and Wastewater Service for Scotland -- What are the Key Enablers in Pursuing both Disaster Risk Reduction and Climate Change Adaptation? Practical Lessons from Asian River Basins -- The Great Glacier and Snow Dependent Rivers of Asia and Climate Change: Heading for Troubled Waters -- Assessment of and Adaptation Measures to the Impacts of Climate Change on Water Resources in China -- Using Waternomics to Develop and Avoid Systemic Shocks to the Economy -- Managing Risks on Egypt Water Resources Security: Climate Change and Grand Ethiopian Renaissance Dam (GERD) as Challenging Aspects -- Water Security Under Conditions of Increased Unpredictability: A Case Study -- Temperature-Rainfall Anomalies and Climate Change: Possible Effects on Australian Agriculture in 2030 and 2050. .
    Abstract: This book highlights the likely impacts of climate change in terms of global and national water securities, how different countries are attempting to address these complex problems and to what extent they are likely to succeed. A major global concern at present, especially after the social and economic havoc that has been caused by COVID-19 in only one year, is how we can return to earlier levels of economic development patterns and then further improve the process so that sustainable development goals are reached to the extent possible by 2030, in both developed and developing countries. Mankind is now facing two existential problems over the next several decades. These are climate change and whether the world will have access to enough water to meet all its food, energy, environment and health needs. Much of expected climate change impacts can be seen through the lens of extreme hydrological events, like droughts, floods and other extreme hydrometeorological events. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. Chapter 12 is available open access under a Creative Commons Attribution-NonCommercial 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XXI, 380 p. 104 illus., 100 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811654930
    Series Statement: Water Resources Development and Management,
    URL: https://doi.org/10.1007/978-981-16-5493-0
    DOI: 10.1007/978-981-16-5493-0
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    Pond Ecosystems of the Indian Sundarbans : An Overview (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Biotic communities. ; Freshwater ecology. ; Marine ecology. ; Bioclimatology. ; Sustainability. ; Environmental management. ; Water. ; Ecosystems. ; Freshwater and Marine Ecology. ; Climate Change Ecology. ; Sustainability. ; Environmental Management.
    Description / Table of Contents: Introduction - Ponds of Indian Sundarban as an important socio-ecological systems -- Assessment of Pond water quality and its impact on health and local livelihood in the Indian Sundarban -- Role of Fe2+ on the enhancement of Phytoplankton Community in pond system of Indian Sundarban -- Role of controlled lime treatment on the productivity of pond ecosystem. .
    Abstract: This book aims to give a holistic overview of the pond ecosystem of Indian Sundarbans. Due to climate change, the Indian Sundarbans faces several challenges. With rising sea levels, islands are disappearing and the increasing salinity in the water and soil has severely threatened the health of mangrove forests and the quality of fresh water, soil and crops. Additionally, there have been serious disturbances to hydrological parameters in the lotic as well lentic ecosystems. This book provides new insights into lentic ecosystem-oriented research in the deltaic ecosystem of GBM-I (Ganga-Brahmaputra-Meghna, Indian Delta). The major findings from various research works are brought together, and the gaps and future possible ways forward are outlined. The book addresses the SDG 6 (Clean Water and Sanitation), SDG 13 (Climate Action) and SDG 14 (Life below Water), with a focus on the ecosystem services of ponds in the Indian Sundarbans. Despite there being many studies on riverine water, ground water and mangrove ecosystems of the Indian Sundarbans, this book offers new insights into the pond ecosystem of the Indian Sundarbans. The outcomes from this book can be utilized by researchers from the inland fisheries sector, environmental managers, professionals, and those who seek to develop ways for making pond ecosystems sustainable.
    Type of Medium: Online Resource
    Pages: XXII, 270 p. 60 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030867867
    Series Statement: Water Science and Technology Library, 112
    URL: https://doi.org/10.1007/978-3-030-86786-7
    DOI: 10.1007/978-3-030-86786-7
    DDC: 551.48
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    Scenarios and Responses to Future Deep Oil Spills : Fighting the Next War (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Environmental chemistry. ; Environmental management. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Water. ; Freshwater and Marine Ecology. ; Environmental Chemistry. ; Environmental Management. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Section I Overview -- 1 Introduction to the volume -- 2 Deep-water oil and gas production in the Gulf of Mexico, and related global trends -- 3 Spilled oil composition and the natural carbon cycle: The true drivers of environmental fate and effects of oil spills -- Section II Geological, Chemical, Ecological and Physical Oceanographic Settings and Baselines for Deep Oil Spills in the Gulf of Mexico -- 4 An overview of the geologic origins of hydrocarbons and production trends in the Gulf of Mexico -- 5 Gulf of Mexico (GoM) bottom sediments and depositional processes: A baseline for future oil spills -- 6 Benthic faunal baselines in the Gulf of Mexico: A precursor to evaluate future impacts -- 7 Linking abiotic variables with macrofaunal and meiofaunal abundance and community -- 8 The asphalt ecosystem of the southern Gulf of Mexico: abyssal habitats across space and time -- 9 Geochemical and faunal characterization in the sediments off the Cuban north and northwest coast -- 10 Mapping isotopic and dissolved organic matter baselines in waters and sediments of Gulf of Mexico -- 11 Toward a predictive understanding of the benthic microbial community response to oiling on the northern Gulf of Mexico coast -- 12 Combining isoscapes with tissue-specific isotope records to re-create the geographic histories of fish -- 13 The utility of stable and radio isotopes in fish tissues as biogeochemical tracers of marine oil spill food web effects -- 14 Modernizing protocols for aquatic toxicity testing of oil and dispersant -- 15 Polycyclic aromatic hydrocarbon baselines in Gulf of Mexico fishes -- 16 Case Study: Using a combined laboratory, field, and modeling approach to assess oil spill impacts -- Section III Simulations of Future Deep Spills -- 17 Testing the effect of MOSSFA (Marine Oil Snow Sedimentation and Flocculent Accumulation) events in benthic microcosms -- 18 Physical processes influencing the sedimentation and lateral transport of MOSSFA in the NE Gulf of Mexico -- 19 Simulating deep oil spills beyond the Gulf of Mexico -- Section IV Comparisons of likely impacts from simulated spills -- 20 Comparison of the spatial extent, impacts to shorelines, and ecosystem and 4-dimensional characteristics of simulated oil spills -- 21 A predictive strategy for mapping locations where future MOSSFA events are expected -- 22 Connectivity of Gulf of Mexico continental shelf fish populations and implications of simulated oil spills -- 23 Evaluating the effectiveness of fishery closures for deep oil spills using a 4-dimensional model -- 24 As Gulf oil extraction goes deeper, who is at risk? Community structure, distribution, and connectivity of the deep-pelagic fauna -- 25 Evaluating impacts of deep oil spills on oceanic marine mammals -- 26 Comparative environmental sensitivity of offshore Gulf of Mexico waters potentially impacted by ultra-deep oil well blowouts -- Section V Preparing for and Responding to the Next Deepwater Spill -- 27 Preparing for the inevitable: ecological and indigenous community impacts of oil spill-related mortality in the United States Arctic marine ecosystem -- 28 Summary of contemporary research on use of chemical dispersants for deep sea oil spills -- 29 Perspectives on research, technology, policy and human resources for improved management of ultra-deep oil and gas resources and responses to oil spills -- Index.
    Abstract: It has often been said that generals prepare for the next war by re-fighting the last. The Deepwater Horizon (DWH) oil spill was unlike any previous – an underwater well blowout 1,500 meters deep. Much has been learned in the wake of DWH and these lessons should in turn be applied to both similar oil spill scenarios and those arising from “frontier” explorations by the marine oil industry. The next deep oil well blowout may be at 3,000 meters or even deeper. This volume summarizes regional (Gulf of Mexico) and global megatrends in marine oil exploration and production. Research in a number of key areas including the behavior of oil and gas under extreme pressure, impacts on biological resources of the deep sea, and the fate of oil and gas released in spills is synthesized. A number of deep oil spills are simulated with detailed computer models, and the likely effects of the spills and potential mitigation measures used to combat them are compared. Recommended changes in policies governing marine oil exploration and development are proposed, as well as additional research to close critical and emerging knowledge gaps. This volume synthesizes state-of-the-art research in deep oil spill behavior and response. It is thus relevant for government and industry oil spill responders, policy formulators and implementers, and academics and students desiring an in-depth and balanced overview of key issues and uncertainties surrounding the quest for deep oil and potential impacts on the environment.
    Type of Medium: Online Resource
    Pages: XII, 542 p. 167 illus., 138 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030129637
    URL: https://doi.org/10.1007/978-3-030-12963-7
    DOI: 10.1007/978-3-030-12963-7
    DDC: 551.48
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    Parched - The Cape Town Drought Story (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Sustainability. ; Environmental management. ; Economic policy. ; Social policy. ; Communication. ; Water. ; Sustainability. ; Environmental Management. ; Socio-Economic Policy. ; Media and Communication.
    Description / Table of Contents: Chapter 1, Introduction -- Chapter 2. Water Supply in Cape Town -- Chapter 3. Reconciliation strategy -- Chapter 4. Politics, trust and governance -- Chapter 5. The Drought -- Chapter 6. Reliance on rainfall, climate variability and climate change -- Chapter 7. The Water Resilience Programme -- Chapter 8. The New Water Programme -- Chapter 9. NWP: Managing dam levels -- Chapter 10. NWP: Managing Demand -- Chapter 11. NWP: Augmentation -- Chapter 12. Lessons learnt -- Chapter 13. Conclusion.
    Abstract: The book presents the history of water supply to Cape Town, leading up to the worst ever drought recorded, through political turmoil impacting on drought interventions and resulting in the adoption of an integrated water strategy. Regions reliant on water supply from rainfed dams have always been vulnerable to the impact of drought. This is exacerbated by the uncertainty of future rainfall, which is never guaranteed, and reliance is placed on modelling using historic data. While weather has always been variable, climate has been generally reliable. With anthropogenic activity causing changes in climate, the validity of modelling based on history is currently not fully trusted. Unless the storage capacity is sufficient to carry through numerous seasons of poor rainfall, even with water restrictions to match demand and supply in times of depleted rainfall, the risk of reservoirs running dry remains a threat.
    Type of Medium: Online Resource
    Pages: XXIX, 290 p. 82 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030788896
    URL: https://doi.org/10.1007/978-3-030-78889-6
    DOI: 10.1007/978-3-030-78889-6
    DDC: 551.48
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    Water Resources Management and Sustainability : Solutions for Arid Regions (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Water. ; Hydrology. ; Sustainability. ; Environmental management. ; Agriculture. ; Environment. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Water. ; Sustainability. ; Environmental Management. ; Agriculture. ; Environmental Sciences. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Wireless Sensor Networks for Hydrological Monitoring, Helpful Tools for Accurate Models -- Automatic Extraction of Surface Water Bodies from High-Resolution Multispectral Remote Sensing Imagery using GIS and Deep Learning Techniques in Dubai -- Multiple Non-Linear Reservoirs to Model Water Balance Components in Sandy Soils -- Flood Mapping and Assessment During Typhoon Ulysses (Vamco) in Cagayan, Philippines using Synthetic Aperture Radar Images.
    Abstract: The book will be of interest to researchers and practitioners in the field of hydrology, environmental engineering, agricultural engineering, earth sciences, and watershed and range sciences, as well as to those engaged in water resources planning, development and management in arid and semi-arid areas. Given the lack of literature on arid regions, this book not only provides an assessment of water resource management in arid regions but also addresses solutions, and it can also be an outstanding textbook on water resources management and sustainability for arid regions. This volume in the Water Science and Technology Library includes selected papers that have been presented and discussed during the International Water Resources Management and Sustainability: Solutions for Arid Regions, 22–-24 March 2022, Dubai, United Arab Emirates. The conference was organized by the National Water and Energy Center, UAE University, in collaboration with the South Australian Goyder Institute for Water Research, and the Department for Environment and Water, Government of South Australia. The conference attracted a large number of nationally and internationally well-known experts who have been at the forefront of water resources management and sustainability in arid and semi-arid regions. More than 55 countries, covering the five continents, were represented. The conference was designed to facilitate and encourage new perspectives on how science and innovative technologies can transform water management and sustainability in arid and semi-arid regions around the world. It addressed current challenges and priorities in water management and provided a forum to share knowledge, experiences, research, and discoveries.
    Type of Medium: Online Resource
    Pages: XIV, 446 p. 223 illus., 194 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031245060
    Series Statement: Water Science and Technology Library, 121
    URL: https://doi.org/10.1007/978-3-031-24506-0
    DOI: 10.1007/978-3-031-24506-0
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    River Health and Ecology in South Asia : Pollution, Restoration, and Conservation (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Physical geography. ; Environmental monitoring. ; Water. ; Freshwater and Marine Ecology. ; Water. ; Physical Geography. ; Environmental Monitoring.
    Description / Table of Contents: Chapter1. River Health and Ecology: Perspective View and Approach -- Chapter2. Arthropods: an important bioindicator to decipher the health of the water of South Asian Rivers -- Chapter3. Anthropogenic stress on river health: with special reference to Kangsabati river, West Bengal, India -- Chapter4. Role of modern biotechnology in the era of river water pollution -- Chapter5. Assessment of chitinolytic bacteria isolated from zooplankton of freshwater ecosystem -- Chapter6. Microplastics in freshwater riverine systems: brief profile, trophic level transfer and probable remediation -- Chapter7. Assessment of River Health through Water and Biological Characteristics -- Chapter8. Estimating Water Quality of the Sundarban Coastal Zone (India) using Landsat Series Satellite Data and Ground Observations -- Chapter9. Anthropogenic impacts on hydro-morphodynamic behaviour in the middle - lower course of Subarnarekha river, India -- Chapter10. Perturbation of the health of riverine ecosystem and its impact on the biogeochemical, ecological and molecular perspectives -- Chapter11. Assessment of habitat quality in quarried reach of alluvial river -- Chapter12. Physicochemical and microbial indicators for water quality assessment in an industrial catchment of river Damodar, India -- Chapter13. Assessment of heavy metal concentration in selected fish species in Subarnarekha River, India -- Chapter14. Assessment of water pollution and aquatic toxicity of the Churni River, India -- Chapter15. River corridor mapping and monitoring using Geospatial Technology -- Chapter16. Micro-plastic pollution in freshwater systems: A potential environmental threat -- Chapter17. Sand and Gravel Mining and its Consequences on Morphometry of Raidak-II River in Eastern Dooars, India -- Chapter18. Resuscitating the regional rivers: a crusade against cauvery crisis and coloured legislations.
    Abstract: This volume reviews recent hydrological and environmental issues resulting from human-induced water pollution practices while providing case studies on the physical, chemical, and eco-biological techniques used to mitigate the impacts of river ecosystem pollution in South Asian countries. The book demonstrates the key methods of measurement, monitoring, mapping, and modeling of river water quality and how it is impacted by pollution and incorporates contemporary geospatial technological applications for the management and sustainability of future water resources. The major topics that the book addresses are the fundamental concepts of river ecosystem health, riverine ecology and habitats, risk assessment of riverine pollution, and technology-based river pollution control strategies. The book will serve as an interdisciplinary guide for researchers, students, and GIS specialists working in various disciplines, including pollution hazards, river ecosystem restoration, water quality, remote sensing, zoology, natural resources management, and environmental geography. .
    Type of Medium: Online Resource
    Pages: XVIII, 420 p. 118 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030835538
    URL: https://doi.org/10.1007/978-3-030-83553-8
    DOI: 10.1007/978-3-030-83553-8
    DDC: 551.48
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    Advances in Hydroinformatics : Models for Complex and Global Water Issues—Practices and Expectations (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Environmental engineering. ; Civil engineering. ; Geographic information systems. ; Mathematics Data processing. ; Water. ; Environmental Civil Engineering. ; Geographical Information System. ; Computational Science and Engineering.
    Description / Table of Contents: Local downscaling of shallow water simulations -- SW2D-LEMON: a new software for upscaled shallow water modelling -- 1D numerical tool for real time modelling of a complex river network -- Rapid simulations of large scale flood inundations using porosity functions -- Numerical and methodological developments in 1D+ ISM models for operational purposes -- Application of a modified parareal method for speeding up the numerical resolution of the 2D shallow water equations -- Validation of a general-purpose erosion-sedimentation model on a laboratory experiment -- Modelling culverts in Basilisk -- Uncertainty quantification in hydrodynamic modelling using the example of a 2D large-scale model of the River Elbe -- Quantification of historical skew surges : challenges and method -- Sensitivity analysis of the digital twin of the canal of Calais to the outlet gate modelling -- Integrated hydraulic-hydrological assimilation chain: towards multisource data fusion from river network to headwaters -- Meandering of the Venoge River at Bois-de-Vaux: in-situ measurements versus 2D numerical predictions -- How to optimally represent riverbed geometry with a simplified cross-section shape in shallow water models? -- Evaluate the influence of groynes system on the hydraulic regime in the ha thanh river, binh dinh province -- Comparison of streamflow estimated by image analysis (LSPIV) and by hydrologic and hydraulic modelling on the French Riviera during 2019 floods -- Analysis of Triple Rectangular Plates Configurations Impacts on Local Scour around Cylindrical Single Bridge Pier -- 2-D simulation of flow entering a building -- Investigation of the hydraulics in flooded housing estate. -- Benefit of coupling 1d-2d model over an urban area to assess runoff during a storm event -- Stream Rehabilitation Design In A Potentially Protected Forest Catchment In Singapore -- Application of a physics based distributed integrated hydrological model in flood risk management -- Risk Analysis for Flash Flood Hazards in China -- Determination and application of dynamic rainfall threshold for flash flood warning -- Optimized Reservoir Prior Release Operation for Flood Control Considering Operational Weekly Ensemble Hydrological Forecast -- Geographical cluster of flash flood hazards in Jiangxi, China: a spatial analysis perspective -- Analysis of extreme precipitation during the Mediterranean event associated with the Alex storm in the Alpes-Maritimes: atmospheric mechanisms and resulting rainfall -- Are hydrologic-hydraulic coupling approaches able to reproduce Alex flash-flood dynamics and impacts on southeastern French headwaters? -- Improving the efficiency of Flash Flood Forecasting and Warning System in Thailand -- Study on Forecasting and Alarming Model of Flush Flood Based on Machine Learning -- Numerical assessment of sediment supply impacting flash flood propagation in mountainous confluences -- Wood debris risk analysis and protection scenarios of Lourdes city using Iberwood model -- A study on flood inundation mapping of surma river floodplain under extreme flood scenario nature based solutions -- A framework for evaluating performance of large-scale Nature-Based Solutions to reduce hydro-meteorological risks and enhance co-benefits -- Managing droughts in Northern Germany Ð The RECONECT NBS Approach and Water resources model for Vier- und Marschlande Area, Hamburg, Germany -- Opportunities and challenges of Natural-Based Solutions in urban areas - French case studies -- The 1915 mud-debris flow at san fruttuoso di camogli: modeling the collapse effects in the portofino pilot area of the h2020 reconect project -- Benefits of green infrastructure for flood mitigation in small rural watersheds - Case study of the Tamnava River in Serbia -- Modelling Nature-Based Solutions with quasi-2D model -- Bregana river basin: hydrodynamic modeling and analysis of nbs suitability within the reconect project.
    Abstract: This book includes a collection of extended papers based on presentations given during the SIMHYDRO 2021 conference, held in Sophia Antipolis in June 2021 with the support of French Hydrotechnic Society (SHF). It focused on "Models for complex and global water issues—Practices and expectations”. The water field is continuously mobilizing models for addressing complex issues and new challenges. Within the context of the climate change, the water issues are exacerbated with the competition among uses. The limited water resources request from the modern societies to review some of the historical paradigms traditionally used and to promote new approaches for a sustainable management. The combined complexity and vulnerability of large urban environments request a deep understanding of water uses and environmental synergy. At the same time, water-related natural hazards are contentiously straightening modern societies that must adapt and implement a more resilient environment. In parallel, in the industrial sector, the search for a high level of efficiency for hydraulic machinery requests to simulate complex processes. Under all these situations, the models currently used represent only partly the physical phenomena involved, the scale of the processes, the hypothesis included within the different numerical tools, etc. The design and the operation of relevant models represent a challenging task for the modeller who is responsible of the knowledge part of a global system that is dedicated to support the decision makers. The book explores both the limitations and performance of current models and presents the latest developments based on new numerical schemes, high-performance computing, multi-physics and multi-scales methods, and better interaction with field or scale model data. It addresses the interests of practitioners, stakeholders, researchers, and engineers active in this field.
    Type of Medium: Online Resource
    Pages: XVIII, 1245 p. 809 illus., 742 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811916007
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-981-19-1600-7
    DOI: 10.1007/978-981-19-1600-7
    DDC: 551.48
    Language: English
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  • 95
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    Nile and Grand Ethiopian Renaissance Dam : Past, Present and Future (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Water-power. ; Environment. ; Geography. ; Water. ; Hydroenergy. ; Environmental Sciences. ; Geography.
    Description / Table of Contents: 1. Introduction -- 2. Pre-colonial, Colonial and Post-Colonial Era: A Look into the Historical Depths of the Nile Waters: What to Learn from History -- 3. Global Perspectives and Regional Lessons: The Nile River and The Prospects of The Grand Ethiopian Renaissance Dam -- 4. Beyond GERD: Hydropolitical, Hydrological, Technological and Investment (HHTI) Imperatives for Sustained Economic Cooperation -- 5. Water Resources Account of Egypt vs Ethiopia's Nile Sub-basins: The Utility of the Concept of Water Budget -- 6. Geographical Dimensions of Hydro-politics: The Case of Nile and Mekong Rivers.
    Abstract: This book is a contribution by the presenters of the 2020 International Conference on the Nile and Grand Ethiopian Renaissance Dam (GERD). The Nile basin is facing unprecedented level of water right challenges after the construction of GERD has begun. Ethiopia, Egypt and Sudan have struggled to narrow their differences on filling and operation of the GERD. The need for science and data-based discussion for a lasting solution is crucial. Historical perspectives, water rights, agreements, failed negotiations, and other topics related to the Nile is covered in this book. The book covers Nile water claims past and present, international transboundary basin cooperation and water sharing, Nile water supply and demand management, Blue Nile/Abbay and Grand Ethiopian Renaissance Dam, land and water degradation and watershed management, emerging threats of the Lakes Region in the Nile Basin, and hydrologic variation and monitoring. This book is beneficial for students, researchers, sociologists, engineers, policy makers, lawyers, water resources and environmental managers and for the people and governments of the Nile Basin.
    Type of Medium: Online Resource
    Pages: IX, 525 p. 158 illus., 147 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030764371
    Series Statement: Springer Geography,
    URL: https://doi.org/10.1007/978-3-030-76437-1
    DOI: 10.1007/978-3-030-76437-1
    DDC: 551.48
    Language: English
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  • 96
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    Climate Change Impact on Groundwater Resources : Human Health Risk Assessment in Arid and Semi-arid Regions (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Climatology. ; Environmental health. ; Environmental monitoring. ; Water. ; Pollution. ; Climate Sciences. ; Environmental Health. ; Environmental Monitoring.
    Description / Table of Contents: Chapter1. Introduction -- Chapter2. Properties of groundwater and its importance -- Chapter3. Groundwater and Health in Semi-arid and Arid Regions -- Chapter4. Groundwater Quality Status of Semi-Arid and Arid Regions -- Chapter5. Assessment of Groundwater Quality mapping for drinking purpose in semi-arid and arid regions of India -- Chapter6. Elimination of Fluoride from Drinking groundwater water Supplies -- Chapter7. Remote Sensing and GIS for groundwater geochemistry -- Chapter8. Groundwater and Artificial Recharge Planning -- Chapter9. Assessment of the appropriateness of drinking and irrigation groundwater -- Chapter10. Hydrological process in arid and semi-arid region -- Chapter11. Factors influencing hydrological process -- Chapter12. Human Health risk assessment -- Chapter13. Climate change Impact of nitrate contamination on human health -- Chapter14. Climate change Impact of fluoride contamination on human health -- Chapter15. Heavy metals influencing factors -- Chapter16. Mitigation Measures of Fluoride and Nitrate Contaminated Regions -- Chapter17. Hydrologic modelling for ungauged basins: An overview of past, present and future directions -- Chapter18 -- Appraising the groundwater potential of Liddar sub-basin (western Himalayas) using geospatial techniques -- Chapter19. Groundwater Potential Zones (GPZ) delineation in Dhamani river basin in Kolhapur district, Maharashtra, India, using Remote Sensing (RS), Geographical Information System (GIS) and Multi-Criteria Decision Analysis (MCDA) techniques -- Chapter20. Assessment of groundwater potential zone mapping for development of semi-arid region through AHP and GIS techniques -- Chapter21/ Assessment of Groundwater Prospective zone in Adigrat Town and its surrounding area using Geospatial Technology -- Chapter22. Computation of rainfall infiltrates into Coastal soil of Andhra pradesh, India -- Chapter23. Feasibility assessment of low-cost filter to adopt in roof top rain water harvesting (RWH) -- Chapter24. Prioritization of sub-watershed through Morphometric Analysis of Amaravathi Watershed using Geoinformatic Techniques -- Chapter25. Conclusion – Climate Change Impact on Groundwater Resources.
    Abstract: This volume discusses climate change impacts on groundwater quality in arid and semi-arid regions, and provides human health risk assessments due to pollution of surface and groundwater. The book presents recent trends in monitoring groundwater management and implementing pollution mitigation strategies, including practices involving remote sensing and GIS techniques, entropy water quality index, weighted arithmetic water quality index, fuzzy logic applications, and improved irrigation methods. The book also outlines hydrological processes in arid and semi-arid regions and hydrochemical properties of surface and groundwater as a necessary background for understanding how pollution impacts groundwater quality and resources, and how geographical modeling of hydrological processes can aid in human health risk assessments. The book is intended for academics, administrators, policymakers, social scientists, and professionals involved in the various aspects of climate change impact on groundwater quality, hydrological process, pollution mitigation strategies, sustainable development, and environmental planning and management. .
    Type of Medium: Online Resource
    Pages: XVI, 480 p. 191 illus., 184 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031047077
    URL: https://doi.org/10.1007/978-3-031-04707-7
    DOI: 10.1007/978-3-031-04707-7
    DDC: 551.48
    Language: English
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  • 97
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    Wastewater Resource Recovery and Biological Methods (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Refuse and refuse disposal. ; Environmental management. ; Pollution. ; Renewable energy sources. ; Water. ; Waste Management/Waste Technology. ; Environmental Management. ; Pollution. ; Renewable Energy.
    Description / Table of Contents: Chapter 1. Sustainable utilization of wastewater: an overview -- Chapter 2. Productions of Bioenergy from Wastewater -- Chapter 3. Production of Biogas from wastewater -- Chapter 4. Various treatment technology for generation of Biogas -- Chapter 5. Biohydrogen production from wastewater -- Chapter 6. Various treatment technologies for the generation of biohydrogen from sludge and wastewater -- Chapter 7. Lipid biomass to Biodiesel -- Chapter 8. Biopolymers from wastewater -- Chapter 9. Recovery of nutrients from wastewater -- Chapter 10. Recovery of various metals from wastewater -- Chapter 11. Resource recovery from wastewater -- 12. Biofertilizers from wastewater -- Chapter 13. Microbial fuel cell and wastewater treatment -- Chapter 14. Various applications of Sludge as resources -- Chapter 15. Future research on the sustainable utilization of wastewater as resources -- Chapter 16. Aerobic treatment of high-strength ammonium wastewater-nitrogen removal via nitrate -- Chapter 17. Thermophilic aerobic biological wastewater treatment -- Chapter 18. Aerobic treatment of winery wastewater using jet-loop activated sludge reactor -- Chapter 19. Advancements in the application of aerobic granular biomass technology for sustainable treatment of wastewater.
    Abstract: The book is unique in highlighting the issue of wastewater as one of the important environmental issues. The uniqueness also lies in exploring the concepts of converting waste into resources in the form of bioenergy, biofertilizers through various biological methods. Given the international scenario, the chapters of this book are designed to include both anaerobic and aerobic methods of resource recovery from the industrial wastewater. The book is a step toward design with nature and the concept of green chemistry. Waste menace is one of the most voiced and unsolved problems in the entire world. The whole world is facing the threat of water pollution, soil pollution/ land pollution, odour pollution from the growing waste. Though we find many missions and programs at international, national, and regional level to solve the waste associated issues, this is mostly in context with the solid fraction of the waste. Very little is being done to manage the liquid part of the waste or what we call the wastewater. The conversion of wastewater has the potential to be converted to energy in the form bioenergy, bio-fertilizers, electricity, nutrient recovery, etc. The use of sludge as biofertilizers solves the problem of sludge management on the one hand and production of organic crops on the other. The biological treatment methods like sludge treatment gives the farmers the source of biofertilizers and organic manure for the plants. In the present scenario, energy crisis is also one of the issues that we are facing particularly in context with the thermal power plants which are environmentally highly polluting. Through various techniques like microbial fuel cells or biohydrogen, we get a source of cleaner energy. So, through this book, we try to produce the content and information to give the audience an understanding of the waste water as one of the environmental and health issues and mitigation strategies. The book gives a sufficient understanding of how waste can be turned into a resource.
    Type of Medium: Online Resource
    Pages: VI, 386 p. 47 illus., 42 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031401985
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-031-40198-5
    DOI: 10.1007/978-3-031-40198-5
    DDC: 551.48
    Language: English
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  • 98
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    Online Resource
    Water Policy in Pakistan : Issues and Options (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Bioclimatology. ; Pollution. ; Environmental management. ; Environmental policy. ; Water. ; Climate Change Ecology. ; Pollution. ; Environmental Management. ; Environmental Policy.
    Description / Table of Contents: Part 1: Background and Setting -- Chapter 1. Introduction (Simi Kamal) -- Chapter 2: Water Resource Potential: Status and Overview (Mohsin Hafeez and Muhammad Arshad) -- Chapter 3: Water Supply and Demand: National and Regional Trends (Shahid Ahmad and Ghufran Ahmad) -- Chapter 4: Water Infrastructure and Institutional Setting (from Chapter 8) (Muhammad Arshad and Fahad Amjad) -- Chapter 5:Political Economy of Water (Erum Sattar) -- Part 2. Sectoral Specific Issues -- Chapter 6: Water and Agriculture – a major area of water policy reforms (Kalim Qamar, Robina Wahaj, Asif Sharif and Mahmood Ahmad) -- Chapter 7: Drinking Water Supply and Sanitation (Naseer Ahmad, and Mitsuo Yoshida) -- Chapter 8: Water Storage and Hydropower (Daud Ahmad and Aslam Rasheed) -- Part 3. Sector-wide Issues -- Chapter 9: Water Pricing, Demand Management, and Allocative Efficiency (Mahmood Ahmad and Ahsan Tayyab) -- Chapter 10: Groundwater Overexploitation and Water Mismanagement (Sanval Nasim) -- Chapter 11: Water Quality and Salinity (Muhammad Abid Bodla, Mohammad Ashraf and Vaqar Zakaria) -- Part 4. Regional. International and Future Issues -- Chapter 12: Wastewater treatment in Pakistan: Issue, challenges and solution (Fozia Parveen, and Sher Jamal Khan) -- Chapter 13: Water Treaties: National and international (Azeem Shah, Erum Sattar) -- Chapter 14: Water and Climate Change: A New Challenge (Asif Khan , Muhammad Zia-ur-Rahman Hashmi and Aisha Khan) -- Chapter 15: Developing knowledge-based capacity for resource management and service delivery (Skill, Information, and Technology-based Resource Management and Service Delivery) (Abubakr Muhammad and James Wescoat) -- Part 5. Looking Ahead -- Chapter 16: Toward Secure Water Future: Timeframe and Strategies (Mahmood Ahmad , Abubakr Muhammad and Ahsan Tayyab ). .
    Abstract: The water policy issues are well- documented in a large set of reports and studies, completed over time showing that the policy prescription and its implementation has been weak in the past as this book reveals. The key reforms initiated were lost due to a lack of government’s will and commitment and more so by pervasive political economy of water. Given this background, each chapter in the book follows a balanced approach in seeking and evaluating alternate solutions to water management issues, especially improvements in water governance and tackling new challenges emerging from the climate change in the short and long term. This approach underpins the importance of moving from the culture of piloting projects to actual implementation on an impact-oriented scale. The book would also highlight that most of the water solutions lie outside the water sector such as agriculture, population, economy, etc. Post COVID-19 policies are exploring new food-health nexus that calls for nature based solutions for our future agriculture growth. The book would show case pioneer work underway in Pakistan on how new policy discourse can reduce water use in agriculture without investing in expensive water technology and infrastructure, thus saving enough water for other competing purposes. .
    Type of Medium: Online Resource
    Pages: XXX, 457 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031361319
    Series Statement: Global Issues in Water Policy, 30
    URL: https://doi.org/10.1007/978-3-031-36131-9
    DOI: 10.1007/978-3-031-36131-9
    DDC: 551.48
    Language: English
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  • 99
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    Online Resource
    Water in Circular Economy (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Energy policy. ; Energy and state. ; Environmental management. ; Sustainability. ; Refuse and refuse disposal. ; Water. ; Energy Policy, Economics and Management. ; Energy Policy, Economics and Management. ; Environmental Management. ; Sustainability. ; Waste Management/Waste Technology.
    Description / Table of Contents: Water as key resource in Circular Economy -- Impact Of Climate Change on Water Status: Challenges and Emerging Solutions -- Integrated Water Management - Directions of Activities and Policies -- Circular Water Management in Smart Cities -- The Influence of Mineral Parameters on the Geochemistry of Heavy Metals in Bottom Sediments -- Sustainable Water Use in Agriculture - Circular Economy Approach -- Innovative Solutions in the Transition to Circular Economy in Water Sector -- Advanced Treatment Technologies in Removal of Pollutants from Water and Wastewater -- The Role of Water Recycling in Building a Circular Economy in the Textile Industry -- The Role of Water Recycling in Building a Circular Economy in the Textile Industry -- Preliminary Microbiological Risk Assessment for Local Water Reuse in a Small MBR Waste Water Treatment Plant -- Can Remote Sensing be a Useful Tool to Increase Water Reuse in Agriculture? -- Nutrients Recovery in Water and Wastewater Sector -- Technologies for Nutrient Recovery From Municipal Wastewater -- Circular Economy in Domestic and Industrial Waste Waters: Challenges and Opportunities -- Monitoring of Circular Economy Implementation in Water Sector -- Water Footprint of Business and Circular Economy -- Economic, Social and Environmental Dimensions in the Circular Economy (CE) Monitoring Framework in Water and Wastewater Sector -- Circular Economy Indicators and Measures in Water and Wastewater Sector – Case Study -- Business Opportunities in Water and Wastewater Sector as a Part of the Resolve Framework -- Circular Economy Implementation in the Water Sector: Wastewater Treatment Plant Tychy-Urbanowice Case Study -- Wastewater-Based Circular Economy Operations in East Kolkata Wetlands (The Largest Ramasar Site in South Asia), India.
    Abstract: This book presents possible solutions for a circuler economy (CE) in the water and wastewater sector through an inventory of multidisciplinary knowledge with high scientific and practical importance which can contribute to support the transition to the CE model in water and wastewater sector. Water in modern studies exceeds being an important source for irrigation and drinking. It is now a significant source of renewable energy and a catalyst in most industrial and manufacturing products. The protection and sustainable management of water resources and water-based waste (as wastewater, sewage sludge, or sewage sludge ash) are important aspects of the CE, which is defined as a regenerative growth model that gives back to the planet more than it takes. Our book, entitled "Water in Circular Economy", delivers a comprehensive overview of the latest research covering the following aspects of water management from the perspective of the CE implementation: · Water as a key resource in the circular economy; · Innovative solutions in transition to the circular economy in water and wastewater sector; · Monitoring of circular economy implementation in water and wastewater sector.
    Type of Medium: Online Resource
    Pages: IX, 254 p. 106 illus., 81 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031181658
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    URL: https://doi.org/10.1007/978-3-031-18165-8
    DOI: 10.1007/978-3-031-18165-8
    DDC: 551.48
    Language: English
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  • 100
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    Pharmacogenomics in Precision Medicine : From a Perspective of Ethnic Differences (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Medical genetics. ; Pharmacology. ; Biomedical Research. ; Medical Genetics.
    Description / Table of Contents: Chapter 1. Introduction and Principles of Pharmacogenomics and Precision medicine -- Chapter 2. Pharmacogenomics in Cardiovascular Diseases -- Chapter 3. Pharmacogenomics of Antitumor Chemotherapeutic Agents -- Chapter 4. Pharmacogenomics of Antitumor Targeted Agent and Immunotherapy -- Chapter 5. Pharmacogenomics of Immunosuppressant -- Chapter 6. Pharmacogenomics of Psychiatric drugs -- Chapter 7. Pharmacogenomics of Anti-Infective Agents -- Chapter 8. Pharmacogenomics of Antithrombotic drugs -- Chapter 9. Pharmacogenomics in Therapeutic Drug Monitoring -- Chapter 10. Pharmacomicrobiomics -- Chapter 11. Genotyping technology in Pharmacogenomics -- Chapter 12. The Ethical, Legal and Regulatory Issues Associated with Pharmacogenomics -- Chapter 13. Cost-effectiveness of pharmacogenetic-guided treatment -- Chapter 14. Application of pharmacogenomics in drug discovery and development -- Chapter 15. Barriers and Solutions in Clinical Implementation of Pharmacogenomics for Personalized Precision Medicine.
    Abstract: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
    Type of Medium: Online Resource
    Pages: VIII, 289 p. 33 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811538957
    URL: https://doi.org/10.1007/978-981-15-3895-7
    DOI: 10.1007/978-981-15-3895-7
    DDC: 615
    Language: English
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