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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Human physiology. ; Neurology . ; Life sciences. ; Physiology. ; Neuroscience. ; Human Physiology. ; Neurology. ; Life Sciences. ; Animal Physiology. ; Life Sciences.
    Description / Table of Contents: Part I: HISTORY -- Chapter 1: Transmissible Spongiform Encephalopathy: from its beginnings to Daniel Carleton Gajdusek -- Part II: GENERAL ASPECTS OF PRIONS -- Chapter 2: The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein -- Chapter 3: Mammalian Prion Structures -- Chapter 4: Insoluble Cellular Prion Protein and Other Neurodegeneration-related Misfolded Protein Aggregates in the Brain of Asymptomatic Individuals -- Part III: CONVERSION AND STRAIN OF PRIONS -- Chapter 5: Prion Conversion and Deformed Templating -- Chapter 6: Prion Strain Interference -- Chapter 7: Molecular Mechanisms Encoding Strains of Prions and Prion-Like Misfolded Proteins -- Chapter 8: Cofactor Involvement in Prion Propagation -- Chapter 9: Prion Protein Conversion and Lipids -- Part IV: ENVIRONMENT AND TRANSMISSION OF PRIONS -- Chapter 10: Prions in the Environment -- Chapter 11: Environmentally Acquired Transmissible Spongiform Encephalopathy -- Chapter 12: Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion -- Chapter 13: Species Barriers in Prion Disease -- Part V: MODELLING OF PRIONS -- Chapter 14: Modeling the Cell Biology of Prions -- Chapter 15: Transgenic Mice Modelling in Prion Diseases -- Chapter 16: Stem Cell Models in Prion Research -- Chapter 17: Drosophila Models of Prion Diseases -- Part VI: HUMAN PRION DISEASES AND OTHER PATHOLOGIES -- Chapter 18: Human Sporadic Prion Diseases -- Chapter 19 Genetic Creutzfeldt-Jakob and Gerstmann-Sträussler-Scheinker Diseases -- Chapter 20: Glycoform-selective Prions in Sporadic and Inherited Variably Protease-sensitive Prionopathies -- Chapter 21: The Spectrum of Tau Pathology in Human Prion Disease -- Chapter 22: Prion Protein Complex with mGluR5 Mediates Amyloid-ß Synaptic Loss in Alzheimer’s Disease -- Chapter 23: Prion and Cancers -- Chapter 24: Protective Role of Cellular Prion Protein in Tissue Ischemic/Reperfusion Injury -- Part VII: ANIMAL PRION DISEASES -- Chapter 25: Bovine Spongiform Encephalopathy -- Chapter 26: Classical and Atypical Scrapie in Sheep and Goats -- Chapter 27: Research models for studying chronic wasting disease -- Part VIII: YEAST PRIONS -- Chapter 28: Introduction to Yeast and Fungal Prions -- Chapter 29: Yeast Prions Are Folded, In-Register Parallel Amyloids Subject to Multiple Anti-prion Systems -- Part IX: DIAGNOSIS AND HUMAN PRION SURVEILLANCE -- Chapter 30: Real-time quaking-induced conversion (QuIC) assays for the detection and diagnosis of human prion diseases -- Chapter 31: Protein Misfolding Cyclic Amplification -- Chapter 32: Skin Misfolded Proteins as Biomarkers for Diagnosis of Prion and Prion-like Diseases -- Chapter 33: Diagnosis of Prion Disease: Conventional Approaches -- Chapter 34: Human Prion Disease Surveillance -- Part X: TREATMENT -- Chapter 35: Overview on Treatment of Prion Diseases and Decontamination of Prions -- Chapter 36: Gene Therapy Strategies for Prophylactic and Therapeutic Treatments of Human Prion Diseases -- Chapter 37: Immunomodulation.
    Abstract: Transmissible spongiform encephalopathies (TSE), now known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. Modern studies, including protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In the second edition of Prions and Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date discussion of these unique infectious pathogens and their associated diseases. The book provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the full range of animal and human prion diseases. As a result, the book contains the most authoritative views about the past, present, and future of prions and prion diseases covering fresh perspectives on important emerging topics such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies.
    Type of Medium: Online Resource
    Pages: XII, 793 p. 81 illus., 62 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031205651
    DDC: 612.8
    Language: English
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  • 2
    Keywords: Neurosciences. ; Pain medicine. ; Neurology . ; Anesthesiology. ; Neuroscience. ; Pain Medicine. ; Neurology. ; Anesthesiology.
    Description / Table of Contents: Introduction to Acute, Chronic, and Episodic Pain -- Inflammation and Pain -- Animal Models of Pain and Anti-inflammatory Treatments -- Inflammatory Mediators, Nociceptors, and Their Interactions in Pain -- Immune and Glial Cells in Pain and Their Interactions with Nociceptive Neurons -- Sex Differences in Neuroimmune Interactions and Pain -- Neuroimmune Interactions in Itch -- Toll-like Receptors in Pain and Itch -- Immunotherapy and Pain -- Cell Therapy and Regenerative Pain Medicine - Preclinical Studies -- Cell-based Therapies in Pain Management -- Platelet-Rich Plasma and Autologous Conditioned Serum: Non-Cellular Biologic Therapies for Neuroimmune Modulation and the Treatment of Arthritis Pain -- Exercise and Diet in the Control of Inflammation and Pain -- Mechanism-Based Pain Therapies -- Neuromodulation in Pain Management -- What Patients Need to Know about Pain Therapy?.
    Abstract: As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be the turning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain.
    Type of Medium: Online Resource
    Pages: X, 364 p. 45 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031292316
    DDC: 612.8
    Language: English
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  • 3
    Keywords: Neurosciences. ; Cognitive neuroscience. ; Psychobiology. ; Human behavior. ; Sociology. ; Neuroscience. ; Cognitive Neuroscience. ; Behavioral Neuroscience. ; Sociology.
    Description / Table of Contents: Molecular imaging of the human emotion circuit -- The neurocognitive mechanisms of unconscious emotional responses -- Social and Affective Neuroscience of Embodiment -- The neuroscience of beauty -- Mirror Neurons … in action: ERPs and neuroimaging evidence -- Sex differences in social cognition -- Development of morality and emotional processing -- Trust in Social Interaction: From Dyads to Civilizations -- The time has come to be mindwanderful: Mind wandering and the intuitive psychology mode -- Social Cognition development and socio affective dysfunction in childhood and adolescence -- Clinical neuroscience meets second-person neuropsychiatry -- EEG and ERPs in the study of Language and Social Knowledge -- fMRI and fNIRS methods for social brain studies: hyperscanning possibilities -- Modulating the Social and Affective Brain with transcranial stimulation techniques -- What our eyes can tell us about our social and affective brain? -- Facial EMG – Investigating the interplay of facial muscles and emotions.
    Abstract: This Open Access book presents the current state of the art knowledge on social and affective neuroscience based on empirical findings. This volume is divided into several sections first guiding the reader through important theoretical topics within affective neuroscience, social neuroscience and moral emotions, and clinical neuroscience. Each chapter addresses everyday social interactions and various aspects of social interactions from a different angle taking the reader on a diverse journey. The last section of the book is of methodological nature. Basic information is presented for the reader to learn about common methodologies used in neuroscience alongside advanced input to deepen the understanding and usability of these methods in social and affective neuroscience for more experienced readers.
    Type of Medium: Online Resource
    Pages: XXXIII, 302 p. 55 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031086519
    DDC: 612.8
    Language: English
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  • 4
    Keywords: Neurosciences. ; Neurology . ; Pharmacology. ; Neuroscience. ; Neurology. ; Pharmacology.
    Description / Table of Contents: Chapter 1: Why study Drug Resistant Epilepsy? -- Chapter 2: Pharmacoresistance in Epilepsy -- Chapter 3: Experimental models for the study of drug-resistant epilepsy -- Chapter 4: On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in Epilepsy -- Chapter 5: Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy -- Chapter 6: Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level? -- Chapter 7: Changes in Targets as an Explanation for Drug Resistance in Epilepsy -- Chapter 8: Cellular and molecular mechanisms of neuroinflammation in drug-resistant epilepsy -- Chapter 9: Contribution of the antiepileptic drug administration regime to avoid the development and/or establishment of pharmacoresistant epilepsy -- Chapter 10: Pharmacogenetics in Epilepsy and Refractory Epilepsy -- Chapter 11: Seizures Induce Hypoxia or Hypoxia Induces Seizures. A Perverse Relationship that Increases the Risk of SUDEP -- Chapter 12: Neonatal excitotoxicity triggers degenerative processes related to seizure susceptibility and pharmacoresistance -- Chapter 13: Cerebrovascular remodeling and the role of vascular endothelial growth factor in the epileptic brain and pharmacoresistance -- Chapter 14: The Role of JNK3 in Epilepsy and Neurodegeneration -- Chapter 15: Application of proteomics in the study of molecular markers in epilepsy -- Chapter 16: GABAergic neurotransmission abnormalities in pharmacoresistant epilepsy: experimental and human studies -- Chapter 17: Genes involved in pharmacoresistant epilepsy -- Chapter 18: Drug-resistant Epilepsy and the Influence of Age, Gender and Comorbid Disorders -- Chapter 19: Indications for Intracerebral Recording in Candidates for Epilepsy Surgery -- Chapter 20: On the Development of New Drugs for the Treatment of Drug Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses -- Chapter 21: Physical exercise as a strategy to reduce seizure susceptibility -- Chapter 22: Ketogenic Diet and Drug-resistant Epilepsy -- Chapter 23: Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy -- Chapter 24: Vagus Nerve Stimulation for Intractable Seizures -- Chapter 25: Non Invasive Brain Stimulation as a potential Therapeutic Procedure in drug-resistant epilepsy -- Chapter 26: Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.
    Abstract: This new edition of Pharmacoresistance in Epilepsy addresses all issues relating to drug-resistance in epilepsy, including studies in patients as well in experimental models and presents the basis for an understanding of recent developments in the pathogenesis and treatment of this condition. Important issues associated with drug-resistant epilepsy are reviewed and updated, such as abnormalities in inhibitory mechanisms, neurotoxicity and changes the immune system associated with this disorder, and the development of drug-resistance as consequence of chronic exposure to antiseizure-medications. Considering that a major obstacle is that epilepsy associated with drug-resistance cannot be controlled with the traditional antiseizure medications, specific chapters describe therapeutic strategies to prevent or reduce the progression of the disease with complementary medical therapies, such as transcranial focal stimulation to promote neuroprotection. Pharmacoresistance in Epilepsy is a valuable resource for anyone working in the field, whether studying epilepsy in the lab or treating it in an office.
    Type of Medium: Online Resource
    Pages: XV, 596 p. 84 illus., 79 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031365263
    DDC: 612.8
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurology . ; Developmental neurobiology. ; Neuroscience. ; Neurology. ; Development of the Nervous System.
    Description / Table of Contents: The development of the cerebellum: from the beginnings -- Part I: Responsibilities and liabilities -- Chapter2. The embryology and anatomy of the cerebellum -- Chapter 3. Cellular and genetic programs underlying cerebellum development -- Chapter 4. Early Purkinje Cell Development and the Origins of Cerebellar Patterning. - Chapter 5. Development of the Fish Cerebellum. -Chapter 6. Cerebellar developmental disorders and cerebellar nuclei -- Chapter 7. Motor circuit abnormalities during cerebellar development -- Chapter8. Developmental disorders of the cerebellum and neurotrophic factors -- Chapter9. Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development -- Chapter10. The ubiquitin proteasome system and cerebellar developmental disease -- Chapter11. Epigenetics and Cerebellar Neurodevelopmental Disorders -- Chapter12.. Hormonal regulation of cerebellar development and its disorders -- Chapter13. Infections of the Cerebellum -- Chapter14. Neuroimmune mechanisms of cerebellar development and its developmental disorders -- Chapter15. Teratogenic influences on cerebellar development -- Chapter16. Primary pediatric brain tumors of the posterior fossa -- Chapter17. Primary pediatric brain tumors of the posterior fossa -- Chapter18. Can cerebellar neurodevelopmental disorders affect behavioral disorders or vice versa -- Chapter19. Neurodevelopmental disorders of the cerebellum: autism spectrum disorder -- Chapter20. Congenital cerebellar disease -- Chapter21. Clinical features, assessment, and management of patients with developmental and other cerebellar disorders -- Chapter22. Epidemiology of cerebellar disorders -- Chapter23. Cerebellar transplantation: a potential model to study repair and development of neurons and circuits in the cerebellum. - Chapter 24. Non-coding RNAs and cerebellar development. - Chapter 25. Defining the Cerebellar Cytoarchitecture Using MRI. .
    Abstract: This updated reference covers diverse aspects of cerebellar development from a full range of viewpoints, including the epidemiology of cerebellar genetic disorders, developmental anatomy, cell biology, genetics, epigenetics, infectious diseases, and mechanisms involved in the regulation of cell fate, while also focusing on information that is relevant to clinicians caring for patients with cerebellar disorders. The chapters are written by experts in the field of cerebellar development, and the chapters cover diseases related to the cerebellum, along with their epidemiology, clinical features, assessment, and management. In addition to updating the content to cover the significant developments in the field since the first edition, the second edition will include new chapters on Non-Coding RNAs and Cerebellar Development, Development of the Fish Cerebellum, the Role of nNOS/NO on Cerebellar Development in Health and Disease, and rehabilitation in cerebellar ataxia. The effect of the COVID-19 on the cerebellum has been included in related chapters. Development of the Cerebellum from Molecular Aspects to Diseases, 2nd edition, is designed to be valuable reference for both neuroscientists and clinicians.
    Type of Medium: Online Resource
    Pages: IX, 639 p. 116 illus., 88 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031231049
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 6
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry.
    Description / Table of Contents: 1.How Immune-inflammatory processes link neurodegenerative and psychiatric disorders -- 2.Gut-Microbiota-Brain Axis: pathophysiological mechanism in neuropsychiatric disorders -- 3.Microbiome- induced autoimmunity and novel therapeutic intervention -- 4.The key role of microlia and circulating monocytes in etipathology neuropsychiatric disorders -- 5.Neuro-immuno-epigenetics of prenatal psychological stress -- 6.C-reactive protein (CRP): a potent inflammation biomarker in psychiatric disorders -- 7.Neuroinflammation, neurognesis and neuroprotection in schizophrenia -- 8.Autoimmue psycosis: concept, clinical manifestation and management -- 9.Stress, autonomic nervous system and kynurenine pathway in major depression -- 10.Brain-gut-microbiome axis in major depression : novel therapeutic approach -- 11.Glial-Neuronal Interaction in Synapses: A Possible Mechanism of the Pathophysiology of Bipolar Disorder -- 12.Neuroimmaging of inflammation in depression and anxiety disorders -- 13.Neuroinflammation and immune-kynureinine pathway in anxiety disorders -- 14.Inflammatory-mediated responses in development of neurogeneartive diseases -- 15.The connection between gut-brain axis and PTSD -- 16.Eating disorders : Gut microbiota-immune-brain interactions -- 17.Sleep-immune crosstalk and sleep disorders -- 18.Obsessive-compulsive disorder: immuno-inflammatory disorder? -- 19.Cytokine, neuroinflammation and neurodeneration in Alzheimer’s disease -- 20.Molecular imaging of neuroinflammation in Alzheimer's disease and MCI -- 21.The role of N-Methyl-D-Aspartate Receptor Neurotransmission and mictobiota in Alzheimer’s disease -- 22.Neuroglial activation and neuroinflammation in the brain of patients with autism -- 23.Suicide and inflammation -- 24.Anti-inflammatory effect of Traditional Chinese Medicine on the concept of Mind-body interface -- 25.Anti-inflammatory therapy as a promising target in neupsychiatric disorders.
    Abstract: This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.
    Type of Medium: Online Resource
    Pages: XVII, 554 p. 28 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811973765
    Series Statement: Advances in Experimental Medicine and Biology, 1411
    DDC: 612.8
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurophysiology. ; Gastroenterology. ; Neuroscience. ; Neurophysiology. ; Gastroenterology.
    Description / Table of Contents: Tools for optogenetic probing of nociceptive pathways; Monitoring activity -- An open science model to accelerate the generation, implementation and distribution of optogenetics and viral tools -- Vagal neuroinflammation accompanying respiratory viral infection: An overview of mechanisms and possible clinical significance -- Stress-induced Visceral Analgesia: Concept and Pathways -- Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders -- EPIGENETIC REGULATION OF STRESS-INDUCED VISCERAL PAIN -- The biomechanics and mechanotransduction in visceral nociception -- VISCERAL NOCICEPTION IN GASTROINTESTINAL DISEASE -- Epithelial-Neuronal Communication in Visceral Pain -- Physiological Mechanisms Underpinning Heightened Perception of Visceral Afferent Signalling in Irritable Bowel Syndrome -- A fentanyl analogue that activates u-opioid receptors in acidified tissues inhibits colitis pain without opioid side effects -- Signalling in the Gut -- Translating colonic sensory afferent peripheral mechanosensitivity into the spinal cord dorsal horn -- Translating colonic afferent peripheral sensitivity into the spinal cord dorsal horn -- Neuron-Microglia Dynamic Duo in Chronic Abdominal Pain -- Pre-clinical Models of Endometriosis -- Spinal afferent innervation of the uterus -- Post-infectious bladder hypersensitivity in the development of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
    Abstract: The chapters in this book are based on the Visceral Pain conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility in 2021. This is one of the hottest fields of science and includes mechanisms involving how the microbiome communicates with the brain and how, when disordered, these mechanisms contribute to clinical diseases such as Irritable Bowel Syndrome and Inflammatory Bowel Disease. Researchers from around the globe presented their latest findings as a review of the current state of the art in the field from both the clinical and scientific points of view. These systems are now appreciated as being critical for shaping our well-being and their disorders underlie chronic clinical conditions of significant morbidity and mortality. The author team includes long-established authorities who significantly contributed to the advances in visceral pain research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field.
    Type of Medium: Online Resource
    Pages: VIII, 255 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031257025
    DDC: 612.8
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Neuropsychology. ; Psychiatry.
    Description / Table of Contents: Part 1: Considering sex and gender in research studies -- Sex and Gender Science -- Best practices in the study of sex? -- Best practices in the study of Gender Differences -- The special case of a lack of sex differences – the naked mole rat? -- Lateralization and -- Part 2: Sex differences in cognitive and mental health across the lifespan -- Depression -- Schizophrenia -- Immune and neurodevelopmental disorders – autism? -- Social Cognition -- Cognition and cognitive ageing -- Part 3: Diseases of the brain and relevance of sex -- Epilepsy -- Stroke -- AD -- Parkinson’s -- Multiple Sclerosis.
    Abstract: Does sex matter when it comes to brain function? This volume attempts to answer this very important question which is of relevance to the disciplines of psychology, neuroscience, psychiatry and neurology. Understanding how brain function and resultant behaviors may differ between the sexes impacts upon our knowledge of the pathology and development of treatments for various neurological and psychiatric disorders, particularly those that show significant sex differences in either prevalence and/or manifestation of symptoms. This volume covers three main themes of research into sex differences in basic neurobiology, psychology, preclinical research and clinical research. It begins by exploring our understanding of sex and gender in relation to both animal and human behaviors and discusses the relevance, and importance, of considering sex and gender when conducting research into brain function and behaviors. The second theme focuses on how sex and gender influence mental health and considers the impact of our immune system and the changes that occur with ageing. Finally, the third aspect focuses on examples of neurological disorder which show sex differences in terms of their aetiology and/or symptomology and considers the relevance in the development of treatment for these disorders including dementia, stroke and multiple sclerosis. This volume is of considerable interest to mental health and neurology professionals, including psychiatrists, neurologists, nurses, allied health clinicians and pharmacists. It is also helpful and important for preclinical researchers working in neuroscience, psychopharmacology and reproductive endocrinology.
    Type of Medium: Online Resource
    Pages: X, 373 p. 70 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031267239
    Series Statement: Current Topics in Behavioral Neurosciences, 62
    DDC: 612.8
    Language: English
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  • 9
    Keywords: Neurosciences. ; Neurology . ; Pharmaceutical chemistry. ; Cognitive neuroscience. ; Neuroscience. ; Neurology. ; Pharmaceutics. ; Cognitive Neuroscience.
    Description / Table of Contents: Part I: Basic Science of Cerebellum and Ataxias -- Functional anatomy of the cerebellum -- Cerebellar physiology -- Cerebellar biochemistry/pharmacology -- Genetics of dominant ataxias -- Autosomal and X-linked degenerative ataxias: from genetics to promising therapeutics -- Seeking therapies for Spinocerebellar Ataxia: from gene silencing to systems-based approaches -- Ion Channel Genes and Ataxia -- Part II: Biomarkers and tools of trials -- How to Design a Therapeutic Trial in SCAs -- Therapy development for spinocerebellar ataxia: Rating Scales and Biomarkers -- Clinical rating scales for ataxia -- Scale for Ocular motor Disorders in Ataxia (SODA): Procedures and Basic Understanding -- Cerebellar learning in the prism adaptation task -- Blood and CSF biomarkers in autosomal dominant cerebellar ataxias -- Part III: Autosomal Dominant Cerebellar Ataxias -- Riluzole in progressive cerebellar ataxias -- ASOs against ATXN2 in preclinical and phase 1 trials -- Antisense oligonucleotide therapy against SCA3 -- Spinocerebellar ataxia type 7: From mechanistic pathways to therapeutic opportunities -- Experimental neurotransplantation for cerebellar ataxias -- Development of mesenchymal stem cells therapy for the treatment of polyglutamine SCA: from bench to bedside -- Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia -- Cerebellar Transcranial Magnetic Stimulation in Cerebellar Ataxias -- Physical therapy in Cerebellar Ataxia -- Part IV: Autosomal Recessive Cerebellar Ataxias -- Recent advances on therapeutic approaches for Friedreich’s Ataxia -- Therapeutic use of interferon gamma in Friedreich ataxia -- Metabolic treatments of cerebellar ataxia -- Clinical Trials in Fragile X-Associated Tremor/Ataxia Syndrome -- Part V: Sporadic Ataxias -- Therapeutic strategies in immune-mediated cerebellar ataxias -- Coenzyme Q10 in MSA -- State of the Art and History of Therapeutics in Ataxias.
    Abstract: Despite the critical importance of the cerebellum in brain functions, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.
    Type of Medium: Online Resource
    Pages: XI, 727 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031243455
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Neurology . ; Neuroscience. ; Neuropsychology. ; Neurology.
    Description / Table of Contents: Chapter 1: Understanding the Mechanisms of Dendritic Arbor Development: Integrated Experimental and Computational Approaches -- Chapter 2: Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive -- Chapter 3: Environmental enrichment and functional plasticity in the hippocampus, an update on the mechanisms involved -- Chapter 4: Translatable Models of Brain and Cognitive Reserve -- Chapter 5: Cognitive Reserve: A Life-Course Perspective -- Chapter 6: Neural Correlates of Brain Reserve: A Neuroimaging Perspective -- Chapter 7: Non-pharmacological Approaches Based on Mind-Body Medicine to Enhancement of Cognitive and Brain Reserve in Humans -- Chapter 8: Roles of Synaptic Plasticity in Functional Recovery After Brain Injury -- Chapter 9: Integrated Methods of Neuromodulation for Guiding Recovery Following Stroke -- Chapter 10: Resilience in Brain Networks After Stroke -- Chapter 11: Epigenetics and brain plasticity: back to function -- Chapter 12: Functional Role of Physical Exercise and Omega-3 Fatty Acids on Depression and Mood Disorders -- Chapter 13: BRAIN RECOVERY IN CHILDHOOD: THE INTERACTION BETWEEN DEVELOPMENTAL PLASTICITY AND REGENERATIVE MECHANISMS -- Chapter 14: Estrogen Neuroprotective Activity After Stroke and Spinal Cord Injury -- Chapter 15: Making Meaning of Acquired Brain Injury: Resources for Functional Recovery -- Chapter 16: An Update on Premorbid Personality Traits and Brain Recovery - Another Aspect of Resilience -- Chapter 17: Psychological Aspects of Recovery After Brain Injury: A Focus on Psychodynamic Factors -- Chapter 18: Artificial Intelligence applications for Traumatic Brain Injury research and clinical management.
    Abstract: The importance of this unique book's approach lies in addressing the impact of neurobiological factors as well as psychological influences on brain recovery following injury. There is growing evidence that emotional, motivational, and cognitive factors along with personality traits play a crucial role in brain plasticity, resilience, and recovery. Topics include synaptic and neuronal plasticity, development of brain reserves, biological markers, environmental factors, emotional resilience, and personality traits. By combining the latest research on neural mechanisms and psychological resilience the authors present a book that will help lead to the development of better treatment strategies for functional recovery from brain damage. The new edition is fully updated throughout and contains completely new chapters on brain recovery in childhood, epigenetic aspects of brain recovery, and artificial intelligence techniques in traumatic brain injury research.
    Type of Medium: Online Resource
    Pages: XXIV, 406 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031249303
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 11
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Zoology. ; Neurochemistry. ; Neuroscience. ; Zoology. ; Neurochemistry.
    Description / Table of Contents: 1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.
    Abstract: This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.
    Type of Medium: Online Resource
    Pages: XII, 501 p. 96 illus., 73 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031123900
    Series Statement: Advances in Neurobiology, 29
    DDC: 612.8
    Language: English
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  • 12
    Keywords: Neurosciences. ; Neurophysiology. ; Developmental neurobiology. ; Neuroscience. ; Neurophysiology. ; Development of the Nervous System.
    Description / Table of Contents: Chapter 1: Introduction: What are dendritic spines? -- Chapter 2: Techniques to render dendritic spines visible in the microscope -- Chapter 3: Electrophysiology of dendritic spines: information processing, dynamic compartmentalization and synaptic plasticity -- Chapter 4: Dendritic spines, synaptogenesis and synaptic pruning for the developmental organization of brain circuits -- Chapter 5: Neurotrophic factors and dendritic spines -- Chapter 6: Glial cell modulation of dendritic spine structure and synaptic function -- Chapter 7: Dendritic spines in learning and memory: from first discoveries to current insights -- Chapter 8: Steroid hormone interaction with dendritic spines: implications for neuropsychiatric disease -- Chapter 9: Morphological features of human dendritic spines.
    Abstract: This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system. The density, shape, and function of spines may indicate the cellular connectivity and synaptic plasticity in normal and pathological conditions. This field has undergone dramatic advances in terms of techniques and experimental findings from in vitro to in vivo data, from animal models to human neurons, and computational models using artificial intelligence. To address these cutting-edge findings, the book provides state-of-the-art, comprehensive coverage with chapters written by the leading international researchers in the field. The authors consider the multiple implications for the study of dendritic spines with broad implications in the neurosciences and related areas.
    Type of Medium: Online Resource
    Pages: XV, 499 p. 123 illus., 103 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031361593
    Series Statement: Advances in Neurobiology, 34
    DDC: 612.8
    Language: English
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  • 13
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Clinical psychology. ; Psychiatry. ; Neuroscience. ; Neuropsychology. ; Clinical Psychology. ; Psychiatry.
    Description / Table of Contents: Preface -- PART 1: To fear or not -- Disambiguating fear as an emotional state vs. threat detection. Molecular and Neural circuits of fear extinction. Psychological and theoretical elements on the concept of fear extinction. Neural circuit of fear extinction: psychophysiology -- PART 2: Individual differences in fear extinction -- The impact of sex differences and sex hormones on fear extinction. Impact of sleep on fear extinction. Impact of stress and exercise on fear extinction. Intersect between the intrinsic and extrinsic factors that modulate fear extinction -- PART 3: Psychopathology -- Fear extinction and its relevance to psychopathology. Developmental fear and its extinction imaging. Fear extinction and adult psychopathology -- Part 4: Therapeutics and neuromodulations of fear extinction -- Exposure therapy and other behavioral therapeutics targeting fear extinction circuits. Novel pharmacotherapeutics targeting fear extinction circuits. Reconsolidation and its link and impact on fear extinction. Technological advances in exposure therapy: virtual and augmented reality. Novel approaches using neurostimulation targeting fear extinction.
    Abstract: This book aims to provide the reader a neuroscientific understanding surrounding a very simple question: how do we learn not to fear? Exploring answers to this question is very important for two reasons. First, learning about the neural mechanisms of fear extinction is of relevance to everyone’s life - it is such a basic yet relevant question to our daily experiences. Therefore, understanding brain mechanisms of fear and its regulation is essential from a basic neuroscience point of view. Second, excessive fear and the inability to regulate its expression is one of the hallmarks of fear-, anxiety-, trauma-, and stressor-related psychopathologies. And as such, learning about how fear is acquired, stored, expressed, and regulated could help advance our understanding of the etiology of psychopathology, the maintenance of symptoms pertaining to failure to regulate fear, and could help us develop novel therapeutics to equip providers and patients with the tools to better quell their fears. The contributions contained in this book are provided by experts in the fields of basic and clinical neuroscience, experimental and clinical psychology, and neuropsychiatry. The contributions are organized to start the reader with basic definitions of how we define fear, how we study its neural circuits at the molecular and cellular levels, how to study human behavior and the brain using state-of-the art experimental and statistical tools, to how much fear contributes to psychopathology. This volume ends with current advances aimed to enhance the capacity to extinguish fear; a clinical result that would aid in the treatment of multiple psychiatric disorders, followed by a discussion on future directions of this highly important and relevant field.
    Type of Medium: Online Resource
    Pages: VIII, 387 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031430053
    Series Statement: Current Topics in Behavioral Neurosciences, 64
    DDC: 612.8
    Language: English
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  • 14
    Keywords: Neurosciences. ; Public health. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Public Health. ; Biomedical Research.
    Description / Table of Contents: 1. The effect of sleep disruption and circadian misalignment on the immune system -- 2. Changes in the sleep and circadian pattern of sleep during the COVID-19 pandemic -- 3. Anxiety and depression during the COVID-19 pandemic and their impact on sleep -- 4. Sleep problems during the COVID-19 pandemic in children and adolescents -- 5.Sleep problems during the COVID-19 pandemic in children and adolescents -- 6. Sleep disturbances among healthcare workers during the COVID-19 pandemic -- 7. Sleep disturbances among patients with COVID-19 infection -- 8. Sleep patterns and sleep disturbances during the lockdown periods -- 9. Impact of COVID-19 Mobility Restrictions on Sleep and Wellbeing -- 10. COVID-19 vaccines and sleep disturbances -- 11. Sleep during the COVID-19 pandemic: structural inequity and racial disparity -- 12. The effect of cognitive-behavioral therapy and coping strategies on sleep disturbances during the COVID-19 pandemic -- 13. Sleep and circadian rhythm in post-COVID-19 patients -- 14. COVID-19 and obstructive sleep apnea -- 15. The correlation between COVID-19 infection and restless legs syndrome -- 16. Impact of COVID-19 pandemic lockdown on disorders of hypersomnolence -- 17. Sleep, Physical Activity, and Diet Patterns During COVID-19 Pandemic -- 18. Impact of screen time during the pandemic of COVID-19 on sleep habits -- 19. Dreams and nightmares during the COVID-19 pandemic -- 20. The impact of the COVID-19 pandemic on sleep medicine services -- 21. Protocols for conducting sleep studies during pandemics -- 22. Management of hospital and home positive airway pressure machines during pandemics -- 23. Telemedicine and telemonitoring of sleep disorders during the COVID-19 pandemic -- 24.Changes in Positive Airway Pressure Application and Practices in Patients with Sleep-Related Breathing Disorder during the COVID-19 Pandemic -- 25. Potential Therapeutic Effects of Melatonin on SARS-CoV-2 Infection.
    Abstract: This book examines the correlation of the coronavirus disease-19 [CE1] [AAS2] (COVID-19) infection with sleep, circadian rhythm, and sleep disorders. The chapters of the book explore sleep problems during the COVID-19 pandemic and its association with psychological distress and also review the prevalence of clinical cases of insomnia, anxiety, and depression in COVID-19 patients. The book further presents the correlation between sleep, circadian rhythms, and immunity that contributes toward more severe COVID-19. It summarizes the evidence on the interplay between circadian biology, sleep, and COVID-19. The chapters of the book discuss the relationship between obstructive sleep apnea (OSA) and adverse COVID-19 outcomes. Towards the end, the book presents studies on the anti-inflammatory, antioxidant, and immunotropic properties of melatonin and provides mechanistic insights into the potential therapeutic use of melatonin during the SARS-CoV-2 infection. The last chapter describes the publication output of sleep-related research during the pandemic and provides an overview and trends on sleep and covid-19 publication output. This book is an excellent source for neurologists, sleep specialists, and public health specialists.
    Type of Medium: Online Resource
    Pages: XXVI, 430 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819902408
    Series Statement: Progress in Sleep Research,
    DDC: 612.8
    Language: English
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  • 15
    Keywords: Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Description / Table of Contents: Sensory Regeneration in the Inner Ear: History, Strategies and Prospects -- Non-mammalian Hair Cell Regeneration: Cellular Mechanisms of Morphological and Functional Recovery -- Cell Junctions and the Mechanics of Hair Cell Regeneration -- Mammalian Hair Cell Regeneration -- Specification and Plasticity of Mammalian Cochlear Hair Cell Progenitors -- Inner Ear Cells from Stem Cells – a Path Towards Inner Ear Cell Regeneration -- Spiral ganglion neuron regeneration in the cochlea: regeneration of synapses, axons and cells -- Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear.
    Abstract: This volume provides a detailed update on progress in the field of hair cell regeneration with emphasis on more "prospective" views of the various facets of regeneration research. Sensory Regeneration in the Inner Ear: History, Strategies and Prospects Mark E. Warchol, and Jennifer S. Stone Non-mammalian Hair Cell Regeneration: Cellular Mechanisms of Morphological and Functional Recovery Madeleine Hewitt, David W. Raible, and Jennifer S. Stone Cell Junctions and the Mechanics of Hair Cell Regeneration Mark A. Rudolf, and Jeffrey T. Corwin Mammalian Hair Cell Regeneration Ruth Taylor, and Andrew Forge Specification and Plasticity of Mammalian Cochlear Hair Cell Progenitors Melissa M. McGovern, and Andrew K. Groves Inner Ear Cells from Stem Cells – a Path Towards Inner Ear Cell Regeneration Amanda Janesick, Eri Hashino, and Stefan Heller Spiral ganglion neuron regeneration in the cochlea: regeneration of synapses, axons and cells Steven H. Green, Sepand Bafti, Benjamin M. Gansemer, A. Eliot Shearer, Muhammad Taifur Rahman, Mark E. Warchol, and Marlan R. Hansen Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear Brandon C. Cox, John V. Brigande, and Bradley J. WaltersDr. Mark Warchol is Professor of Otolaryngology at Washington University School of Medicine in St. Louis. Dr. Jennifer Stone is Research Professor of Otolgaryngolldy/Head and Neck Surgery, University of Washington School of Medicine, Seattle. Dr. Allison Coffin is an Associate Professor in the Department of Integrative Physiology and Neuroscience at Washington State University Vancouver. Dr. Arthur N. Popper is Professor Emeritus and research professor in the Department of Biology at the University of Maryland, College Park. Dr. Richard R. Fay (Deceased) was Distinguished Research Professor of Psychology at Loyola University Chicago.
    Type of Medium: Online Resource
    Pages: XVI, 229 p. 44 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031206610
    Series Statement: Springer Handbook of Auditory Research, 75
    DDC: 612.8
    Language: English
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  • 16
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Zoology. ; Life sciences. ; Behavior genetics. ; Neuroscience. ; Zoology. ; Life Sciences. ; Behavioral Genetics.
    Description / Table of Contents: Chapter 1. Introduction to neurogenetics -- Chapter 2. Neurogenetic analysis in Caenorhabditis elegans -- Chapter 3. Regionalisation of the early nervous system -- Chapter 4. Early neurogenesis and gliogenesis in Drosophila -- Chapter 5. Neural stem cells and brain tumour models in Drosophila -- Chapter 6. Eye development in Drosophila: from photoreceptor specification to terminal differentiation -- Chapter 7. Neurogenetics of memory, learning and forgetting -- Chapter 8. Evolution and origins of nervous systems -- Chapter 9. Neural stem and progenitor cells in the mammalian brain -- Chapter 10. Models of neurodegenerative diseases.
    Abstract: This textbook provides students with knowledge of neurogenetics, neurogenesis, neuronal specification and function, neuronal networks, learning and memory formation, brain evolution, and neurodegenerative diseases. Students are introduced to topics of classical developmental genetics as well as modern molecular and neurogenetic methods. Using a wealth of examples from current research, the textbook takes a strong applied approach. Using animal models such as Drosophila melanogaster and Caenorhabditis elegans as well as mammalian systems, the interrelationships between genes, neurons, nervous systems, and behaviour under normal and pathological conditions are illustrated. The textbook aims encourage students to address biological questions in neurogenetics and to think about the design of their own experiments. It targets primarily master and graduate students in neurobiology, but is also a valuable teaching tool for instructors in these fields.
    Type of Medium: Online Resource
    Pages: VII, 212 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031077937
    Series Statement: Learning Materials in Biosciences,
    DDC: 612.8
    Language: English
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  • 17
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Endocrine glands. ; Immunology. ; Neuroscience. ; Endocrine System. ; Immunology.
    Description / Table of Contents: Part I. Concepts -- Chapter 1. A History of Immune and Neuroendocrine System Interactions -- Chapter 2. Philosophical Perspectives on Neuroendocrine-Immune Interactions: The Building Block Model and Complementary Neuro-Endocrine-Immune-Microbiota Systems Approaches -- Chapter 3. The Behavioural Immune System of Lower Vertebrates -- Part II. Regulatory Pathways -- Chapter 4. Cytokines and Hypothalamo-Pituitary-Adrenal Axis Activation: Now a Classic of Immune-Neuroendocrine System Interactions -- Chapter 5. Catecholamines and Immunomodulation -- Chapter 6. Neuroendocrine-immune Interactions in Major Depressive Disorder: Glucocorticoids and Glucocorticoid Receptors -- Chapter 7. Brain Fluids, Blood-Brain Interfaces, and Their Involvement in Neuroimmune Regulation During Development and in Adulthood -- Chapter 8. Neuropeptide Binding Autoantibodies Regulating Neuroendocrine Communications -- Part III. Modulation -- Chapter 9. Postnatal Development of Neuroimmune Responses -- Chapter 10. Sex Differences in Neuroendocrine-Immune Interactions -- Chapter 11. Biological Clocks and Immune Function -- Chapter 12. Influence of the Gut Microbiota on Neuroendocrine-Immune Interactions -- Part IV. Disease -- Chapter 13. Energy Balance and Neuroendocrine-Immune Regulation in Chronic Inflammatory and Neoplastic Diseases: An Evolutionary Perspective -- Chapter 14. Autonomic, Immune, Metabolic and Neuroendocrine Dimensions of Anorexia Nervosa: An Integrative View.
    Abstract: The concepts of the neuroendocrine system and the immune system emerged more or less simultaneously in the second half of the 20th century. Although these systems have a high degree of autonomy, it has also become clear that they interact in many ways and at different levels. This book focuses on the neuroendocrine and immune interactions that are fundamental to normal development and maintenance of health. The first introductory chapters are devoted to the historical and philosophical concepts within the field, as well as evolutionary considerations, offering critical interdisciplinary perspectives on the development of this field of research. Without attempting an exhaustive overview, the book then introduces some of the regulatory pathways that mediate interactions between the neuroendocrine and immune systems and examines modulating factors such as age and sex. In addition, several chapters address the importance of neuroendocrine-immune interactions in some disease states. Readers can expect to gain a broad perspective of neuroendocrine-immune interactions in development, health, and disease, along with a critical evaluation of current methods used in the field. Given its scope, the book is essential reading for undergraduate and graduate students with an interest in neuroendocrinology, neuroimmunology, and neuroscience, as well as postdoctoral fellows and established researchers seeking a comprehensive overview and historical perspective of the field of neuroendocrine-immune interactions.
    Type of Medium: Online Resource
    Pages: XIII, 386 p. 29 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031213588
    Series Statement: Masterclass in Neuroendocrinology, 13
    DDC: 612.8
    Language: English
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  • 18
    Keywords: Neurosciences. ; Neuroanatomy. ; Neurophysiology. ; Developmental neurobiology. ; Cognitive neuroscience. ; Neuroscience. ; Neuroanatomy. ; Neurophysiology. ; Development of the Nervous System. ; Cognitive Neuroscience.
    Abstract: This monograph, now in its 2nd edition with 31 new chapters and significant updates, is the first book of its kind written specifically for graduate students and clinicians. The monograph is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013; 2nd edition: 2022), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology and related areas. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. Essentials of the Cerebellum and Cerebellar Disorders makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. It is organized into easy to read and short chapters that are ideal for students and clinicians. The most common cerebellar disorders encountered in the clinic are covered. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from cerebellar laboratories and ataxia clinics throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar cellular biology and circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.
    Type of Medium: Online Resource
    Pages: XIV, 742 p. 182 illus., 127 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031150708
    DDC: 612.8
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Psychiatry. ; Neurology . ; Neuroscience. ; Psychiatry. ; Neurology.
    Description / Table of Contents: A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.
    Abstract: The Dictionary of Hallucinations, second edition, is an alphabetical listing of issues pertaining to hallucinations and other misperceptions. They can be roughly divided into four categories: 1. Definitions of individual hallucinatory symptoms 2. Medical conditions and substances associated with the mediation of hallucinations 3. Historical figures who are known to have experienced hallucinations 4. Miscellaneous issues Each of the definitions of individual hallucinatory symptoms includes: a definition of the term its etymological origin the year of introduction (if known) a reference to the author or authors who introduced the term (if known) a description of the current use a brief explanation of the etiology and pathophysiology of the symptom at hand (if known) references to related terms references to the literature The second edition of A Dictionary of Hallucinations serves as a reference manual for neuroscientists, psychiatrists, psychiatric residents, psychologists, neurologists, historians of psychiatry, general practitioners, and academics dealing professionally with concepts of hallucinations and other sensory deceptions. This new edition provides updated information and references, and includes newly discovered hallucinations, bringing together contributions by other authorities within the field, with all the entries edited by Prof. Blom.
    Type of Medium: Online Resource
    Pages: XXVI, 790 p. 604 illus., 364 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031252488
    DDC: 612.8
    Language: English
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  • 20
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Pharmacology. ; Neuroscience. ; Pharmacology.
    Description / Table of Contents: Chapter 1 Overview of the relationship between aluminum exposure and health of human being.-Chapter 2 The Chemistry of Human Exposure to Aluminum -- Chapter 3 Entry and Deposit of Aluminum in Brain -- Chapter 4 Aluminum as a CNS and immune system toxin across the life span.-Chapter 5 Occupational exposure to aluminum and cognitive impairment -- Chapter 6 Debated relationship between Exposure to Aluminum in Daily Life and Alzheimer’s Disease -- Chapter 7 Animal Model of Aluminum-Induced Alzheimer’s like Disease -- Chapter 8 Aluminum-induced AD-like Pathological Features.-Chapter 9 Aluminum induced neural cells death -- Chapter 10 Aluminum-Induced Electrophysiological Variation, Synaptic Plasticity Impairment, and Related Mechanism.-Chapter 11 Cross Talk Between Aluminum and Genetic Susceptibility -- Chapter 12 Epigenetic modification in aluminum-induced neuron death and synaptic impairment -- Chapter 13 Neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) -- Chapter 14 Alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects.
    Abstract: This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid beta—the pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment. The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects is also added. In closing, this book provides readers with a systematic summary of aluminum neurotoxicity.
    Type of Medium: Online Resource
    Pages: XVIII, 313 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789819915927
    DDC: 612.8
    Language: English
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  • 21
    Keywords: Neurosciences. ; Neurology . ; Neurophysiology. ; Neuropharmacology. ; Neuroscience. ; Neurology. ; Neurophysiology. ; Neuropharmacology.
    Description / Table of Contents: Molecular Biomarkers.Somatic instability/Telomeres,- Genetic modifiers -- Current clinical trial biomarkers.-Pharmacodynamic biomarkers for Htt-lowering therapeutics.-Inflammatory biomarkers.-Sleep dysregulation markers.-Mitochondrial/Oxidative stress biomarkers.-Microbiomics -- Metabolomics.-Proteomics.-Transcriptomics.-Lipidomics.-Imaging marker overview.-Retinal imaging biomarkers -- MRI - non-invasive functional MRI measures -- The evolution of clinical trial methodology.-Digital biomarkers -- The future of telehealth -- Summary and future trends.
    Abstract: Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents a distinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important.
    Type of Medium: Online Resource
    Pages: XVI, 475 p. 42 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031328152
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Regenerative medicine. ; Stem cells. ; Neuroscience. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology.
    Description / Table of Contents: Part 1 General considerations -- Human iPS for clinical applications and cellular products -- 3D-printed iPS disease models -- Part 2 CNS iPSC and organoids -- iPS-derived neurons and brain organoids from patients (brain) -- iPS-derived RGCs (eye) -- iPS-derived glia (brain) -- iPSC to model blood-brain barrier endothelial cells -- Part 3 iPSC-derived nociceptive neurons -- IPSC-based peripheral nerve modeling -- Part 4 Non-neuronal specialized cell types -- iPSC-based drug screening of differentiated cardiomyocyte subtypes -- iPSC-based cardiac disease modeling: from cell to tissue -- iPSC-derived corneal endothelial cell -- iPSC-derived trabecular meshwork (eye) -- iPSC for in vitro disease modeling of diabetes.
    Abstract: Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has been lost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.
    Type of Medium: Online Resource
    Pages: VIII, 332 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031423499
    Series Statement: Handbook of Experimental Pharmacology, 281
    DDC: 612.8
    Language: English
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  • 23
    Keywords: Geology. ; Sedimentology. ; Paleontology . ; Geophysics. ; Geology. ; Sedimentology. ; Paleontology. ; Geophysics.
    Description / Table of Contents: Chapter 1. Surface Geology of Kuwait -- Chapter 2. Subsurface stratigraphy of Kuwait -- Chapter 3. Sand dunes in Kuwait, morphometric and chemical characteristics -- Chapter 4. Marine Geology of Kuwait -- Chapter 5. Structures and Tectonics of Kuwait.
    Abstract: This open access book contains a set of chapters covering all aspects of geosciences related to Kuwait and adjactent regions, including Iran, Saudi Arabia and the Arab Gulf states. It covers basic information about the geology including a wide range of geoscientific disciplines such as marine geology, structural geology, hydrogeology and geophysics related to the region. This book is aimed at researchers and students, as well as professionals in the field of hazard mitigation and petroleum exploration.
    Type of Medium: Online Resource
    Pages: XII, 242 p. 211 illus., 177 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031167270
    Series Statement: Regional Geology Reviews,
    DDC: 551
    Language: English
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  • 24
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Sedimentology. ; Paleontology . ; Petrology. ; Geology. ; Sedimentology. ; Paleontology. ; Petrology.
    Description / Table of Contents: Chapter 1 - Field guide for a complete cross-section of the Central Andes along main roads (Carla Cristine Porcher, Márcia Elisa Boscato Gomes, Amós Martini, Giuseppe Betino De Toni, João Pacífico Machado) -- Chapter 2 – Structures associated with the dynamics of granitic rock emplacement (NW Portugal) (Jorge Pamplona, Benedito C. Rodrigues, Mark Peternell, Alex Lorenz, Alex Schimdt, Melissa Mengert, Thomas Altmeyer, Jonas Köpping) -- Chapter 3 - Tectonically significant fault zones in Central Europe (Germany, Czech Republic and Poland) and their surface and subsurface outcrops: Franconian Line, Hronov-Porici Fault, Sudetic Marginal Fault and Lusatian Fault (Lucie Novakova) -- Chapter 4 - Geological field observations along the Pandoh Syncline:the Mandi-Kataula-Bajura section of Himachal Pradesh, NW-India (Paramjeet Singh, Pratap Chandra Sethy, Hrithik Rastogi, M. Rajanikanta Singh, A. Krishnakanta Singh, Satyajit Singh Thakur, Saurabh Singhal) -- Chapter 5 - The rock outcrops at Raghunathdi, SE of Ghatsila (Jharkhand, India): A spectacular preservation of polyphase folding (Srinanda Ganguly, Arpita Samanta, Abhik Kundu) -- Chapter 6 - Spectacular soft-sediment deformation structures in sedimentary rock outcrops of Damodar Valley Basin, West Bengal, India: A field guide (Arpita Samanta, Abhik Kundu) -- Chapter 7 - Structural geological field guide: Bhuj area (Gujarat, India) (Nidhi Lohani, Soumyajit Mukherjee, Seema Singh, Aashu Pawar, Mohamedharoon Shaikh) -- Chapter 8 - Structural and sedimentary field studies in Angul District, Odisha, India (Subhajit Sinha, Ananya Ghosh, Somnath Mishra) -- Chapter 9 - New Structural geological input from the Barmer Basin, Rajasthan (India) (Mohit Kumar Puniya, Ashish Kumar Kaushik, Soumyajit Mukherjee, Swagato Dasgupta, Nihar Ranjan Kar, Mery Biswas, Ratna Choudhary) -- Chapter 10 - Structural geology and stability issue of the Giral lignite mine, Rajasthan, India (Mohit Kumar Puniya, Ashish Kumar Kaushik, Soumyajit Mukherjee, Nihar Ranjan Kar, Mery Biswas, Ratna Choudhary) -- Chapter 11 - Relationship between deformation structures and rock mass rating: A case study of underground power house, Andhra Pradesh- India (Mohit Kumar Puniya, Sohan Kumar, Ashish Kumar Kaushik, Nikhil Puniya) -- Chapter 12 - Macrostructures mimic Meso-structures (Harsh Bhu, Ritesh Purohit, Riya Dutta) -- Chapter 13 - Review on Role of multi-constellation Global Navigation Satellite System-Reflectometry (GNSS-R) for real-time sea-level measurements (Kutubuddin Ansari) -- Chapter 14 - Architecture and structures of Kiradu temple (Barmer region, Rajasthan, India) (Paramita Haldar,, Mohit Kumar Puniya, Mery Biswas, Soumyajit Mukherjee, Nihar Ranjan Kar, Ratna Choudhary).
    Abstract: This book is the second volume of an edited work aiming to help novice geologists to explore terrains independently. Geoscience fieldwork with focus on structural geology and tectonics has become more important in the last few years from both academic and industrial perspectives. This book also works as a resource material for batches of students or geological survey professionals undergoing training as parts of their course curriculum/training. Industry persons, on the other hand, can get a first-hand idea about what to expect in the field, in case no academic persons are available with the team. This book focuses on structural geology and tectonics and compiles terrains from several regions of the globe. This book also includes field guide chapters for primary sedimentary structures.
    Type of Medium: Online Resource
    Pages: XVI, 418 p. 323 illus., 304 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031195761
    Series Statement: Springer Geology Field Guides, FieldGuides,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Geodynamics. ; Geomorphology. ; Physical geography. ; Geology. ; Geodynamics. ; Geomorphology. ; Physical Geography.
    Description / Table of Contents: 1. Geo-tectonic and, topographic, and geographical setting of the Leh-Ladakh region: study scope and methodology -- 2. Overview of the Geology, Structure, and Tectonics of the Ladakh Batholith and Indus Suture Rocks -- 3. Geology and Lithological Variations of the Ladakh Batholith within the Leh-Ladakh Region -- 4. Structural Geology of the High Strain Zone: Ladakh Batholith, Leh Region, NW India -- 5. Structural Geology of the Northern and North-Eastern Zone (N-NE Zone), Leh-Ladakh Region.
    Abstract: This book presents the first report and interpretation of the deformation, structural style, and geo-tectonic evolution of a 600km2 area of the Ladakh batholith, NW India, centred on the city of Leh, Ladakh. The Ladakh (and westerly Kohistan ) batholith comprises a large component of the Jurassic-Oligocene Kohistan-Ladakh Arc-Terrane (KLA), with magmatism spanning island arc, continental margin, and post-Himalayan collision tectonic environments. The KLA is bounded to the north by the Shyok-Northern Suture and to the south by the Indus Suture. The batholith illustrates basement thick-skin tectonic deformation and is divided/partitioned into a series of crustal blocks separated by lateral accommodation structures which allow independent movement in horizontal and vertical space. Thin skinned deformation within the adjacent sedimentary molasse Indus Suture Rocks produced large thrust stacks that predominantly moved towards the N-NE. Whilst deformation within cover sequences influences the basement structures, and helps break up the basement into crustal blocks, there is a clear distinction in deformation between the basement and cover sequences. Basement batholith deformation is more complex and heterogeneous, reflecting the variable transmission of tectonic stress within crystalline crust and the presence of a wide range of precursory inherited weaknesses and anisotropies. Models of time-space deformation are presented using data derived from field and extensive photograph / photo-mosaic image interpretation. The batholith was deformed during at least Palaeocene-Pliocene times at crustal depths that correspond to the ductile-brittle transition zone and shallower.
    Type of Medium: Online Resource
    Pages: XLV, 149 p. 136 illus., 135 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315664
    Series Statement: Springer Geology,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Geographic information systems. ; Data mining. ; Geology. ; Natural Hazards. ; Geographical Information System. ; Data Mining and Knowledge Discovery. ; Geology.
    Description / Table of Contents: Chapter 1. Geological disaster: An overview -- Chapter 2. Research methods of geological disasters -- Chapter 3. Principles and methods of intelligent interpretation of geological disasters -- Chapter 4. Intelligent analysis of multi-source long-term landslide ground monitoring data -- Chapter 5. Intelligent monitoring of landslides based on high-resolution optical remote sensing data -- Chapter 6. Deep learning-based remote sensing monitoring of landslide -- Chapter 7. Deep learning-based landslide susceptibility assessment -- Chapter 8. Deep learning-based intelligent recognition of ground fissures -- Chapter 9. Machine learning-based remote sensing monitoring of land subsidence in mining areas -- Chapter 10. Concluding remarks.
    Abstract: This book comprehensively utilizes the new generation of artificial intelligence and remote sensing science and technology to systematically carry out researches on high-precision recognition, monitoring, analysis, and assessment of geological disasters by using different technologies of "ground, airspace, and space-based systems" and different scales of "target-semantic-region". The main contents include: 1) Intelligent interpretation theory and methods of geological disasters, 2) Intelligent analysis of landslide based on long-term ground monitoring data, 3) Deep learning-based remote sensing detection of landslide, 4) Intelligent analysis of landslide evolution based on optical satellite remote sensing data, 5) Intelligent assessment methods of landslide susceptibility, 6) Intelligent recognition of ground figure based on airspace-based remote sensing data, The book is of interest to graduate student, scientific, and technological personnel who work in the area of geological disasters, natural hazards, remote sensing, and artificial intelligence.
    Type of Medium: Online Resource
    Pages: XII, 233 p. 85 illus., 79 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819958221
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Bioclimatology. ; Public health. ; Urban ecology (Biology). ; Architecture. ; Human geography. ; Natural Hazards. ; Climate Change Ecology. ; Public Health. ; Urban Ecology. ; Cities, Countries, Regions. ; Human Geography.
    Description / Table of Contents: Disaster Resilience and Human Settlements: Emerging Perspectives in the Anthropocene -- Leaving nothing to chance: reducing flood risk by evaluating simulation exercises in urban contexts -- Urban growth and increasing flood impact in the city of Palma: a loss of resilience capacity -- Addressing the Impacts of Inland Floods on Informal Housing in Honiara, Solomon Islands -- Adaptive Capacity Analysis of Flood Prone Regions in Bihar, India -- Cruise tourism, risk perception and public narratives in Syracuse, Italy -- Social media in risk perception and disaster management: a geographical perspective -- Environment as a Weapon: History, Gaia, and the Geohazards of War -- Living on Mount Etna between risk, beauty and need: a field survey on villages struck by 2018 earthquake -- Narratives of urban resilience and sustainability in southern Italy: the case studies of Matera (Basilicata) and Filadelfia (Calabria) -- Disaster resilience assessment for drainage network and urban landscape after heavy meteorological events: examples from the middle Adriatic coastal area (Abruzzo Region, Central Italy) -- Revitalizing the wounded territory: the “geo-hiking's” potential -- Sense of belonging and response to climate change: how the relation with local territories influences climate resilience -- From Disasters to the Pandemic: A Study on the EU Solidarity Fund.
    Abstract: This book presents emerging perspectives on disaster resilience and human settlements in the larger context of the Anthropocene. The chapters explore urban and rural perspectives focusing on the current and emerging perspectives on disaster resilience through a holistic approach, involving scientists, humanists, planners, policymakers, and professionals in the global debate.
    Type of Medium: Online Resource
    Pages: XXX, 312 p. 106 illus., 89 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819922482
    Series Statement: Advances in 21st Century Human Settlements,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Petrology. ; Paleontology . ; Earth sciences. ; Geology. ; Petrology. ; Paleontology. ; Earth Sciences.
    Description / Table of Contents: Overall paleogeographic and geodynamic evolution -- Major Groundwater reservoirs in Egypt -- Western Desert Petroleum sources and reservoirs -- Nile Delta Petroleum sources and reservoirs -- Gulf of Suez and Red Sea Petroleum sources and reservoirs -- Off-shore Mediterranean discoveries -- Petroleum Source Rocks of Egypt – An Integrated Palynological and Organic Geochemical Approach: Spatio-temporal studies within the Phanerozoic of Egypt -- Carbonate platform deposits and hydrocarbon potentiality -- Hydrocarbon seepage during the Messinian salinity crisis -- Rare Earth Element in Egypt -- Phanerozoic Stratabound/Stratiform Ore Deposits of Egypt.
    Abstract: The Phanerozoic Geology and Natural Resources of Egypt includes a series of chapters written by highly qualified group of researchers whose expertise is recognized and appreciated not only in Egypt, but also in the world over. The chapters span a wide range of geological subdisciplines including tectonics, paleogeography, stratigraphy, sedimentology, paleontology, groundwater, and energy resources, just to name a few. In this regard, the book provides the reader with ample knowledge about the different facets of the fascinating and always intriguing geology of Egypt since the Precambrian time. For a junior researcher or a geoscience student, the book is a comprehensive, multidisciplinary one-stop resource that they will continue to reference and rely on for years to come. For a more experienced scientist, the book summarizes the current state of knowledge, highlights the magnitude of complexity of the geology of Egypt and northeast Africa, and reveals potential areas where future research should be directed. The book is written in simple, easy to understand English language and contains very useful high-quality illustrations. Last but not least, The Phanerozoic Geology and Natural Resources of Egypt has been reviewed and edited by world class, highly ranked geoscientists from Egypt, Europe, and USA.
    Type of Medium: Online Resource
    Pages: XIX, 742 p. 593 illus., 529 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783030956370
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Physical geography. ; Environmental sciences Social aspects. ; Water. ; Hydrology. ; Emergency medical services. ; Natural Hazards. ; Earth System Sciences. ; Environmental Social Sciences. ; Water. ; Emergency Services.
    Description / Table of Contents: Chapter 1. Linkage Between Social and Hydrological Systems to Support Resilience: A Case of Freshwater Wetland in Bangladesh -- Chapter 2. Indigenous Approaches to Disaster Risk Reduction, Community Sustainability and Climate Change Resilience -- Chapter 3. The Adaptation to Climate Change in the Primary Education and Approach from the Social Sciences Textbooks -- Chapter 4. Building Climate Change Adaptation and Risk Knowledge In the Arctic Through Preparedness and Contingency Practices -- Chapter 5. Ecological Resilience for Transformative Climate Change Mitigation and Adaptation -- Chapter 6. Mitigating Disaster Risks and Vulnerabilities through Climate Finance and Sustainable Water Management: Policy Considerations for Sub-Saharan Africa and Malawi -- Chapter 7. Assessing Risks and Resilience to Hydro-meteorological Disasters -- Chapter 8. Flood Resilient Plan for Urban Area: A Case Study -- Chapter 9. Flood and Drought Risk Assessment, Climate Change and Resilience -- Chapter 10. Flood Risk Predictions in African Urban Settlements: A Review of Alexandra Township, South Africa -- Chapter 11. Anthropological Study of a Typical Drought Prone Village in India- Strategies for Sustainable Rural Habitat -- Chapter 12. Risk Management of Extreme Precipitation in Mexico: Building Resilience -- Chapter 13. Increasing Temperature Risk and Community Resilience: Urban Aspects -- Chapter 14. Climate Change Adaptation and Sustainable Development -- Chapter 15. Climate Change, Food Security and Resilience: Hydrologic Excess and Deficit Measurement -- Chapter 16. Climate Change and Agro Forestry Resilience Strategy In West Africa’S Cocoa Supply Chain Dynamics -- Chapter 17. Spatial-Temporal Changes of Water Resources: Associated Impact as a Natural Hazard -- Chapter 18. Vulnerability of Climate Change on Water and Sanitation Sectors and Coping Mechanisms by the Communities of Economically Poor Hard to Rich Areas of Bangladesh -- Chapter 19. Climate Governance, Resilience and Enterpreneurship In Nigeria: An Empirical Review.
    Abstract: This book is part of a six-volume series on Disaster Risk Reduction and Resilience. The series aims to fill in gaps in theory and practice in the Sendai Framework, and provides additional resources, methodologies, and communication strategies to enhance the plan for action and targets proposed by the Sendai Framework. The series will appeal to a broad range of researchers, academics, students, policy makers, and practitioners in engineering, environmental science and geography, geoscience, emergency management, finance, community adaptation, atmospheric science, and information technology. This volume offers indigenous approaches to disaster risk reduction, community sustainability and climate change resilience, as well as agro-ecological innovations for improving resilience to climate change. The focus is on adaptation strategies for sustainable terrestrial and marine ecosystems to reduce the impacts of anthropogenic factors that exacerbate disaster risk, including hydro-meteorological services for climate resilience, food security measures in agriculture and livestock, flood mitigation plans, and increased climate change education and awareness. The book concludes with three case studies in Africa detailing the impacts of strengthened climate change resilience measures, adaptive social protections, and improved water availability through hydro-electric technologies. .
    Type of Medium: Online Resource
    Pages: XVI, 457 p. 134 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031221125
    DDC: 551
    Language: English
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    Keywords: Geology. ; Geotechnical engineering. ; Mining engineering. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences. ; Mining and Exploration.
    Description / Table of Contents: Chapter 1: Optimization of The Medium Model in Solving the Inverse Dynamic Problem of Seismics in the HRS-GEO Technology Based on the Spectral Characteristics of Seismic Data -- Chapter 2: Experimental Evaluation of Information Content Regarding the Resolution of the Wave Field and the Choice of Basic Parameters for Solving the Inverse Dynamic Problem of Seismics -- Chapter 3: Features of Integrated Dynamic Interpretation of High Resolution Acoustic Characteristics and Geological Indicators of the Real Environment -- Chapter 4: Wells Data Geophysical Research Interpretation Features -- Chapter 5: Detail Interpretation of High Resolution Seismic Data Timan-Pechora Province.
    Abstract: This book outlines the scientific, methodological and practical foundations for applying High Resolution Seismic HRS-Geo Technology in order to build detailed 2D and 3D seismic acoustic models in the form of acoustic impedances (AI) and reflection coefficients (RC) and the most important geological indicators. The monograph is a continuation of the book by the same authors "Oil and Gas Reservoir Prospecting and Exploration: High-Resolution Seismic HRS techniques and technology". Particular attention is paid to improving the process of searching for AI and RC models using the vector of objective functions, in which various types of residuals between real and model data are iteratively calculated. The well-known criteria for predicting the oil and gas potential of productive deposits from the standpoint of the system analysis principles and the set of geological indicators found from the HRS data are analyzed. The features of solving the main seismogeological problems using HRS-Geo Technology modules are shown, illustrated by numerous examples, and using a special (optimal) processing graph and a set of additional seismic record regularization procedures that provide maximum detail of high-resolution seismic data. The book is meant for scientists and specialists involved in in-depth complex geological interpretation of seismic data in the search and exploration of oil and gas deposits, as well as students of geophysical and geological specialties, graduate students of these specializations and developers.
    Type of Medium: Online Resource
    Pages: XXVIII, 382 p. 170 illus., 169 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031415906
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Geotechnical engineering. ; Geology. ; Geographic information systems. ; Climatology. ; Geodynamics. ; Natural Hazards. ; Geotechnical Engineering and Applied Earth Sciences. ; Geology. ; Geographical Information System. ; Climate Sciences. ; Geodynamics.
    Description / Table of Contents: Part I: ICL Landslide Lesson -- Advancements in shear strength interpretation, testing, and use for landslide analysis -- Rock Avalanches in the Tibet Plateau of China -- Part II: Original articles -- Landslide Susceptibility Zonation Using GIS-based Frequency Ratio Approach in the Kulon Progo Mountains Area, Indonesia -- Physically-based regional landslide forecasting modelling: model set-up and validation -- Consequence - frequency matrix as a tool to assess landslides risk -- Do not let your guard down: landslide exposure and local awareness in Mexico -- Landslides in Higher Education Curricula and Beyond -- Community Scale Landslide Resilience: A citizen-science approach -- Remedial Measures Impact on Slope Stability and Landslide Occurrence in Small-Scale Slope Physical Model in 1g Conditions -- Surficial geology and geomorphology of the North Slide, Thompson River valley, British Columbia: application of fundamental geoscience information to interpretations of geospatial monitoring results -- High Resolution Numerical Weather Simulation for Orographic Precipitation as an Accurate Early Warning Tool for Landslide Vulnerable Terrains -- Climate Change as Modifier of Landslide Susceptibility: Case Study in Davao Oriental, Philippines -- Fractal-based evaluation of the spatial relationship between conditioning factors and the distribution of landslides (A case study in Tinh Tuc, Cao Bang province, Vietnam) -- Procedure of Data Processing for the Improvement of Failure Time of a Landslide Based on the Velocity and Acceleration of the Displacement -- Numerical analysis of the effect of rainfall on the stability of sandstone-covered mudstone cutting slopes -- Part III: Review articles -- Post-formation behaviour of Hattian Landslide Dam and post-breaching situation -- Investigation of debris flow impact mechanisms and designs -- A review of the disaster risk assessment perspectives -- Part IV: IPL/WCOE/KLC2020 -- Application of LAND-SUITE for landslide susceptibility modelling using different mapping units. A case study in Croatia -- An Integrated approach to landslides risk management for local and national authorities -- Assessing landslide hazard in the High City of Antananarivo, Madagascar (UNESCO Tentative site) -- Part V: ICL Landslide Teaching Tools -- Teaching Tools for LS-Tsnnamis -- Part VI: Technical Notes and Case Studies -- CliRtheRoads – An integrated approach to landslide risk management on roads in Serbia -- Part VII: World Landslide Reports -- Rock slope instabilities affecting the AlUla archaeological sites (KSA) -- Refugees’ perception of landslide disasters: Insights from the Rohingya camps in Cox’s Bazar, Bangladesh.
    Abstract: This open access book provides an overview of the progress in landslide research and technology and is part of a book series of the International Consortium on Landslides (ICL). It gives an overview of recent progress in landslide research and technology for practical applications and the benefit for the society contributing to understanding and reducing landslide disaster risk. Prof. Irasema Alcántara-Ayala is a former Director and current Professor at the Institute of Geography of the National Autonomous University of Mexico (UNAM). She is a member of the UNDRR R-STAG of the Americas and an Editor of the ICL book series P-LRT. Prof. Željko Arbanas is the Vice President of the ICL for Europe. He is a professor at the Faculty of Engineering, University of Rijeka, Croatia. He is an Assistant Editor-in-Chief of the International Journal Landslides and the ICL book series P-LRT. Dr. David Huntley is Research Scientist with the Geological Survey of Canada and Open Learning Faculty at Thompson Rivers University, British Columbia. He is an Editor of the ICL book series P-LRT. Prof. Kazuo Konagai is a Professor Emeritus at the University of Tokyo and Principal Researcher of the ICL headquarters. He is an Assistant Editor-in-Chief of the ICL book series P-LRT. Prof. Snježana Mihalić Arbanas a Professor of the Faculty of Mining, Geology and Petroleum, University of Zagreb in Croatia. She is the Chair of ICL Network Committee. Matjaž Mikoš, Professor at the Faculty of Civil and Geodetic Engineering, University of Ljubljana, Slovenia, is the Chairman of the Global Promotion Committee of the International Programme on Landslides and Kyoto Landslide Commitment 2020. Dr. Maneesha Vinodini Ramesh is the Provost of Amrita Vishwa Vidyapeetham, Dean, School for Sustainable Development, Director, AMRITA Center for Wireless Networks & Applications, Amrita Vishwa Vidyapeetham, India. She is an Editor of the ICL book series P-LRT. Prof. Kyoji Sassa is the Founding President and the Secretary General of the ICL and the Secretary General of the Kyoto Landslide Commitment 2020. He is the Editor-in-Chief of the International Journal Landslides and the ICL book series P-LRT. Dr. Shinji Sassa is the Head of Soil Dynamics Group and Research Director at Port and Airport Research Institute, National Institute of Maritime, Port and Aviation Technology, Japan. He is an Editor of the International Journal Landslides and the ICL book series P-LRT. Prof. Huiming Tang is the Vice President of China University of Geosciences (Wuhan) and a Chief Professor at the Faculty of Engineering. He is a full member of ICL, Chairman of the Engineering Geology commission of China and Vice President of IAEG. Prof. Binod Tiwari is the Vice President of the ICL for America. He is a professor of civil and environment engineering at the California State University, Fullerton California, USA. He is an Assistant Editor-in-Chief of the ICL book series P-LRT.
    Type of Medium: Online Resource
    Pages: XV, 503 p. 415 illus., 402 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031442964
    Series Statement: Progress in Landslide Research and Technology,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geotechnical engineering. ; Geophysics. ; Water. ; Hydrology. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences. ; Geophysics. ; Water.
    Description / Table of Contents: Introduction. The Premise of Well Tests -- Chapter 1. Qualitative Aspects: Pattern Recognition -- Chapter 2. Quantitative Aspects: Parameter Estimation -- Chapter 3. Special Cases of Gas and Gas Condensate Wells -- Chapter 4. Naturally Fractured Reservoirs -- Chapter 5. Hydraulically Fractured Wells -- Chapter 6. Horizontal Wells -- Chapter 7. Interference and Pulse Tests -- Chapter 8. Unconventional Wells -- Chapter 9. Injection Well tests -- Chapter 10. Drill Stem Tests -- Chapter 11. Pumping Well Tests -- Chapter 12. Geothermal Wells -- Chapter 13. Computer Aided Methods -- Chapter 14. Testing Water wells and Aquifers -- Chapter 15. Subsurfcae Fluid Disposal and Energy Storage -- Chapter 16. Designing Well Tests.
    Abstract: This book is about the technology of using fluid production or injection and pressure measurement signals from wellbores and relating those signals to the subsurface geology and subterranean reservoir properties. It is aimed at students of well-testing and practicing petroleum engineers or geoscience professionals for subsurface characterization and modeling. The topics include the art and science of well-test analysis, pattern recognition of rate and pressure signals, and a quantitative approach for estimating important subsurface geological parameters for subsurface aquifers and reservoirs containing oil, gas, and geothermal resources. The book is also particularly of value as a guide to asset managers actively developing unconventional reservoirs and CCUS.
    Type of Medium: Online Resource
    Pages: XVII, 191 p. 184 illus., 145 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031472992
    DDC: 551
    Language: English
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    Keywords: Geology. ; Geomorphology. ; Cultural property. ; Archaeology. ; Geology. ; Geomorphology. ; Heritage Management.
    Description / Table of Contents: 1. Introduction -- 2. Volcanology -- 3. Geomorphology -- 4. Hierro geopark -- 5. Landscapes -- 6. Cultural -- Rural.
    Abstract: This open access book explores El Hierro Island, which is geologically the youngest of the Canary Islands (Spain). Having registered its latest volcanic eruption in 2011-2012, it is an oceanic subtropical island with low population pressure and a largely unchanged natural landscape. Accordingly, a great geodiversity of volcanic morphologies and erosion processes has been preserved. In addition, half of the land is protected as a Biosphere Reserve and as a UNESCO Global Geopark, and the island is pursuing energy self-sufficiency. Local tourism is a sustainable activity, as the main attractions are either diving or hiking through the island’s various volcanic landscapes. Covering these and other aspects, and using accessible language, the book will appeal to scientists specialized in geotourism, active leisure entrepreneurs, and members of the general public interested in volcanic geoheritage and geotourism.
    Type of Medium: Online Resource
    Pages: VII, 123 p. 57 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031072895
    Series Statement: Geoheritage, Geoparks and Geotourism, Conservation and Management Series,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Geomorphology. ; Geotechnical engineering. ; Natural Hazards. ; Geomorphology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Chapter 1. Aim and Outline of the Book Series “Progress in Landslide Research and Technology (Kyoji Sassa) -- Part I. International Consortium on Landslides and International Programme on Landslides -- Chapter 2. International Consortium on Landslides: from IDNDR, IGCP, UNITWIN, WCDRR 2 & 3 to Kyoto Landslide Commitment 2020 (Kyoji Sassa) -- Chapter 3. International Programme on Landslides – A Short Overview of its Historical Development (Matjaž Mikoš) -- Part II. Original Articles -- Chapter 4. Understanding and Reducing the Disaster Risk of Landslide-induced Tsunamis: Outcome of the Panel Discussion and the World Tsunami Awareness Day Special Event of the Fifth World Landslide Forum (Shinji Sassa) -- Chapter 5. Natural-hazard-related web observatory as a sustainable development tool (Matjaž Mikoš) -- Chapter 6. Mapping post-fire monthly erosion rates at the catchment scale using empirical models implemented in GIS. A case study in Northern Italy (Damiano Vacha) -- Chapter 7. Mechanisms of shallow rainfall-induced landslides from Australia: insights into field and laboratory investigations (Ivan Gratchev) -- Chapter 8. Design protection barriers against flow-like landslides (Sabatino Cuomo) -- Chapter 9. Landslide warning systems in low- and lower-middle-income countries: future challenges and societal impact (Irasema Alcántara-Ayala) -- Chapter 10. The role of translational landslides in the evolution of cuesta topography (Shinro Abe).
    Abstract: This open access book is the first issue of the first volume of the ICL new book series “Progress in Landslide Research and Technology,” founded by the Launching Declaration of the ICL Open Access Book Series “Progress in Landslide Research and Technology (P-LRT)” for the Kyoto Landslide Commitment 2020 on 3 November 2021 during the Fifth World Landslide Forum (WLF5) in Kyoto, Japan. This book contains the followings: Forewords for the book series and Opening Greetings of WLF5 International Consortium on Landslides and International Programme on Landslides Original articles Review articles IPL Projects, World Centres of Excellence on Landslide Risk Reduction, and Kyoto Landslide Commitment 2020 ICL Landslide Teaching Tools Technical notes and Case studies Official Promoters of the Kyoto Landslide Commitment 2020 (public and private) List of ICL members Prof. Kyoji Sassa is the founding President and the Secretary General of the ICL and the Secretary General of the Kyoto Landslide Commitment 2020. He is the Editor-in-Chief of the International Journal Landslides and ICL book series P-LRT. Prof. Kazuo Konagai is Professor Emeritus of the University of Tokyo and Principal Researcher at the ICL headquarters. He is an Assistant Editor-in-Chief of the ICL book series P-LRT. Prof. Binod Tiwari is the Vice President of the ICL for America. He is a professor of civil and environmental engineering and the Associate Vice President for Research and Sponsored Projects at the California State University, Fullerton, California, USA. He is an Assistant Editor-in-Chief of the ICL book series P-LRT. Prof. Zeljko Arbanas is the Vice President of the ICL for Europe. He is a professor at the Faculty of Civil Engineering, University of Rijeka, Croatia. He is an Assistant Editor-in-Chief of the International Journal Landslides and ICL book series P-LRT. Dr. Shinji Sassa is Head of Soil Dynamics Group and Research Director of International Research Center for Coastal Disasters, Port and Airport Research Institute, National Institute of Maritime, Port and Aviation Technology, Japan. He is an Editor of the International Journal Landslides and ICL book series P-LRT.
    Type of Medium: Online Resource
    Pages: XXX, 474 p. 470 illus., 439 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031168987
    Series Statement: Progress in Landslide Research and Technology,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Human ecology Study and teaching. ; Environment. ; Environmental management. ; Geology. ; Environmental Studies. ; Environmental Sciences. ; Environmental Management.
    Description / Table of Contents: An Overview of World Deserts with Special Reference to Thar Desert -- People and Culture of the Thar Desert -- Shift in Land Use Pattern of Thar Desert -- Land and Water Resource Management in the Thar Desert Region -- Crop Production Practices in the Thar Desert Region of Rajasthan -- Livestock and its Management Practices in Thar Desert, Rajasthan -- Arid Agroforestry for Thar Desert -- Soil Conservation and Water Harvesting for Sustainable Agriculture in Arid Regions -- Community Land Management in the Thar Desert -- Women Empowerment in Thar Desert Region -- Livelihood Opportunities in the Thar Region -- Potential Agri-Business in the Thar Desert -- Multidimensional Development in Thar Desert Region of Rajasthan -- Sustainable Natural Resource Management in Thar Desert-Way Ahead. .
    Abstract: This book covers a wide range of issues related to the Thar Desert Region of Rajasthan from an integrated and sustainable development perspective. The chapters in this book cover regional and local issues which are discussed with reference to the past scenario, the present practices, and the future strategies. Some of the issues addressed in this book like arid agroforestry, livelihood, and multidimensional development give it a cutting edge over other related publications currently available in the market. The chapters are supported with relevant pictures which will help the reader to connect with the issues being discussed. This book is useful to students, civil services aspirants, researchers, environmentalists, geographers, and non-professionals who are interested in deserts and desert development.
    Type of Medium: Online Resource
    Pages: XXII, 342 p. 52 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031345562
    DDC: 551
    Language: English
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    Keywords: Geology. ; Sedimentology. ; Mining engineering. ; Geotechnical engineering. ; Power resources. ; Geology. ; Sedimentology. ; Mining and Exploration. ; Geotechnical Engineering and Applied Earth Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Chapter 1. The Mediterranean Sea: a laboratory to characterize micro-continental drift and oceanic basin formation processes -- Chapter 2. The westernmost Tethyan margins in the Rif Belt (Morocco), a review -- Chapter 3. The Tellian units, the Sellaoua window and the High Medjerda foreland in the Souk Ahras area, NE Algeria -- Chapter 4. Facies Analyses and Basin Evolution of the Cretaceous-Tertiary Rift-related Sedimentary Succession of Haddat Ash Sham area, West Central Arabian Shield, Saudi Arabia -- Chapter 5. Petroleum system evaluation of Upper Cretaceous and Eocene plays, offshore and onshore southern Pelagian Basin, Tunisia.
    Abstract: This book summarizes the links between the evolution of sedimentary basins of Northern Africa and Peri-Mediterranean in different tectonic settings and the distribution of georesources in those basins. Georesources include fossil energy, geothermal energy, deep aquifers, minerals and deposits. This book also provides key information for energy resources in these important areas. The book is in part a compilation of selected papers from Atlas Georesources International Congress, Hammamet, Tunisia, (AGIC 2017) which were extended after the congress in addition to other contributions from geoscientists based at some universities and companies from the region. It is organized in a set of research studies focusing on the architecture, geodynamic evolution and modeling of sedimentary basins in the Middle East, North Africa and the Mediterranean domain. Future developments in the exploration for water, energy and other georesources are very important in these regions. In this context, this book constitutes an important reference for a wide range of geoscientists and companies as it defines the distribution and potentialities of these resources. .
    Type of Medium: Online Resource
    Pages: XVIII, 284 p. 233 illus., 224 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031187476
    Series Statement: Regional Geology Reviews,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Public health. ; Electronic data processing Management. ; Diseases Animal models. ; Natural Hazards. ; Public Health. ; IT Operations. ; Disease Models.
    Description / Table of Contents: Chapter 1. Origins of FASSSTER -- Chapter 2. Management of COVID-19 Data for the FASSSTER Platform -- Chapter 3. FASSSTER Data Pipeline and DevOps -- Chapter 4. Disease Surveillance Metrics and Statistics -- Chapter 5. Effective Reproduction Number Rt -- Chapter 6. The FASSSTER SEIR Model -- Chapter 7. Geospatial and Spatio-Temporal Models. .
    Abstract: This book provides an overview of the extensive work that has been done on the design and implementation of the COVID-19 Philippines Local Government Unit Monitoring Platform, more commonly known as Feasibility Analysis of Syndromic Surveillance Using Spatio-Temporal Epidemiological Modeler for Early Detection of Diseases (FASSSTER). The project began in 2016 as a pilot study in developing a multidimensional approach in disease modeling requiring the development of an interoperable platform to accommodate input of data from various sources including electronic medical records, various disease surveillance systems, social media, online news, and weather data. In 2020, the FASSSTER platform was reconfigured for use in the COVID-19 pandemic. Using lessons learned from the previous design and implementation of the platform toward its full adoption by the Department of Health of the Philippines, this book narrates the story of FASSSTER in two main parts. Part I provides a historical perspective of the FASSSTER platform as a modeling and disease surveillance system for dengue, measles and typhoid, followed by the origins of the FASSSTER framework and how it was reconfigured for the management of COVID-19 information for the Philippines. Part I also explains the different technologies and system components of FASSSTER that paved the way to the operationalization of the FASSSTER model and allowed for seamless rendering of projections and analytics. Part II describes the FASSSTER analytics and models including the Susceptible-Exposed-Infected-Recovered (SEIR) model, the model for time-varying reproduction number, spatiotemporal models and contact tracing models, which became the basis for the imposition of restrictions in mobility translated into localized lockdowns.
    Type of Medium: Online Resource
    Pages: XX, 159 p. 65 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819931538
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Geodynamics. ; Energy policy. ; Energy and state. ; Geochemistry. ; Geology. ; Geodynamics. ; Energy Policy, Economics and Management. ; Geochemistry.
    Description / Table of Contents: Introduction -- Tectonic Framework of Sanjiang Tethyan Metallogenic Domain -- Basic Characteristics and Evolution of Sanjiang Tethys Archipelagic Arc-Basin System -- Formation and Evolution of Sanjiang Collision Orogenic Belt -- Mineralization and Metallogenic System in Sanjiang Region -- Regional Metallogenic Models -- Geological Prospecting Method of Sanjiang and Integration of Exploration Technologies.
    Abstract: This open access book presents a new structural model of “multi-arc-basin-terrane system” based on the in-depth research of the Nujiang-Lancangjiang-Jinshajiang region, especially several Paleo-Tethys ophiolitic mélange belts and sets of arc-basin systems, and a new orogenic model of “The Hengduanshan Mountains” based on penetrated research on spatial-temporal framework and orogenic models of different orogenic belts under large-scale strike-slip-shear-nappe structures evolution. The authors paid special attention on the coupling relation between orogeny and metallogenesis. The metallogenesis and dynamic process are probed under the crust–mantle interaction and material-energy exchange-transmission background and the tectonic units evolution. The ore genesis and distribution of deposits have been thoroughly analyzed, and the metallogenic theories of "multi-arc-basin-terrane" and "intracontinental tectonic transformation" in the Nujiang-Lancangjiang-Jinshajiang region have been carried out. This book also illustrates how to explore metallic deposits in the Nujiang-Lancangjiang-Jinshajiang region by using the metallogenic regulations. Meanwhile, this book has high reference value for researchers working in the fields of basic geology, environmental geology, and energy geology.
    Type of Medium: Online Resource
    Pages: XV, 307 p. 170 illus., 86 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936526
    Series Statement: The China Geological Survey Series,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Physical geography. ; Political science. ; Natural Hazards. ; Environmental Social Sciences. ; Earth System Sciences. ; Governance and Government.
    Description / Table of Contents: Report on the 4th Global Summit of Research Institutes for Disaster Risk Reduction (4thGSRIDRR2019) -- Enhancing disaster preparedness and building resilience: UNESCO's multi-hazard, multi-disciplinary, and multi-stakeholder approach on Disaster Risk Reduction -- Presentation on “The Sendai Framework and Science Advice to Governments to Support Implementation – Suggestion on What Works” -- Presenting the “Global Risk Assessment Framework (GRAF), UNISDR – Emphasising the Relevance of Disaster Research Institutes” -- DRMKC: A collaborative approach to foster resilience -- INFRASTRUCTURE RESILIENCE: A FRAMEWORK FOR ASSESSMENT, MANAGEMENT AND GOVERNANCE -- Harnessing Scientific Knowledge and Technological Innovation for Disaster Risk Reduction (DRR) in Sub-Saharan Africa-Case of Social Media -- Concept Notes for Group Discussion Sessions -- Community resilience against flood: the case of the LIFE PRIMES project -- Yonmenkaigi System Method as an Educational Framework for Climate Change within the United Kingdom: A Pilot Study -- Personalizing a Low cost weather forecasting system -- Transforming Flood Risk Management: A Case of Kakching, Manipur, India -- Adaptive Architecture- A Pathway to Resilient Communities -- RETURN PERIOD ANALYSIS OF MAJOR FLOOD EVENTS CONSIDERING HOMOGENEOUS REGIONS -- Conceptual Design for Flood Warning Study at Recreational Area – Case study Gunung Pulai Mountain, Johor, Malaysia -- IMPACT OF VIBRATION AND MOISTURE CONTENT TO LIGHT NON-AQUEOUS PHASE LIQUID MIGRATION IN DOUBLE POROSITY MEDIA -- Resolution of the 4th Global Summit of Research Institutes for Disaster Risk Reduction: Increasing the Effectiveness and Relevance of our Institutes Held at the Disaster Prevention Research Institute (DPRI), Kyoto University, Kyoto, Japan from 13th to 15th March 2019 -- Closing Ceremony. .
    Abstract: This book presents selected papers by the keynote speakers and other presenters from various disciplines and includes their opinions and evaluations. The Fourth Global Summit of Research Institutes for Disaster Risk Reduction (4th GSRIDRR, 2019): Increasing the Effectiveness and Relevance of our Institutes, sponsored by the Global Alliance of Disaster Research Institutes (GADRI) and Kyoto University, was hosted by and held at the Disaster Prevention Research Institute (DPRI), Kyoto University, Uji Campus, Kyoto, Japan, 13–15 March 2019.. The Global Summit series provided a platform for researchers, practitioners, policy makers, and other stakeholders in both government and non-governmental institutes involved in disaster risk reduction and resilience to come together to discuss, share, and exchange ideas. It focuses specifically on contributing input to the contextualization and revision of the goals of the 2016 Science and Technology Roadmap to implementation of the Priority Areas of the Sendai Framework for Disaster Risk Reduction Agenda 2015–2030, with input for GADRI to move forward in its contributions to the worldwide science community. The conference comprised an impressive array of global stakeholders whose expertise and experience encompassed the management of knowledge and its application for governments and industries, with shared outcomes to bridge science and decision making. It enhanced a process to confront new scientific challenges in disaster risk reduction and disaster risk management. The conference accomplished the following major goals, among others: (1) engagement in dialogue on issues related to disaster prevention and contributions to the Science and Technology Roadmap adopted to support the implementation of the Sendai Framework Agenda 2015–2030; (2) evaluation of current efforts on global and national involvement in the field of disaster prevention research in relation to the implementation of the Priority Areas of the Sendai Framework for Disaster Risk Reduction 2015–2030; (3) assessment of the status of current research knowledge and efforts, and research results at the institutional level in each country.
    Type of Medium: Online Resource
    Pages: XXI, 330 p. 113 illus., 104 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811955662
    Series Statement: Disaster and Risk Research: GADRI Book Series,
    DDC: 551
    Language: English
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  • 40
    Keywords: Natural disasters. ; Geographic information systems. ; Geography. ; Water. ; Hydrology. ; Environmental monitoring. ; Atmospheric science. ; Natural Hazards. ; Geographical Information System. ; Geography. ; Water. ; Environmental Monitoring. ; Atmospheric Science.
    Description / Table of Contents: Part 1. Multi-hazards monitoring -- Chapter 1. Evaluating the Multi Hazards Threats Due to Aridity, Sea Level Upsurge in the Coastal Areas of North Tamil Nadu, South India -- Chapter 2. Active Tectonics and Associated Channel shifting pattern of Neora river basin, Darjeeling Himalaya -- Chapter 3. Estimating Soil Loss Rate and Sediment Yield of the Proposed Ngololweni Earth Dam, Kingdom of Eswatini -- Chapter 4. Flood susceptibility mapping using GIS and multi-criteria decision analysis in Dibrugarh district of Assam, North-East India -- chapter 5. Effects of climatic hazards on agriculture in the Teesta basin of Bangladesh -- Chapter 6. Mizoram, the capital of landslide: A review of articles published on landslides in Mizoram, India -- Chapter 7. Deployment of Geostatistical and Geospatial Technology for Groundwater Quality Vulnerability Assessment Using Hydrogeochemical Parameters: A Case Study of NCT Delhi -- Chapter 8. A Literature Review of the Impact of Covid-19 Pandemic on Land Surface Temperature and Air Quality of India -- Chapter 9. Seasonal and Inter-Annual Variation of Chlorophyll and Sea Surface Temperature in Northern and Southern Arabian Sea, India -- Chapter 10. Application of a geospatial based subjective MCDM method for flood susceptibility modeling in Teesta River basin, West Bengal, India -- Chapter 11. Flood Frequency Analysis of Baitarani River using three probability distributions -- Chapter 12. Application of Analytical hierarchy process (AHP) method to flood risk assessment at Sub-Himalayan region using geospatial data: A case study of Alipurduar district, West Bengal, India -- Chapter 13. Remote Sensing and GIS Based Landslide Susceptibility Mapping: A Case Study from Kegalle District, Sri Lanka -- Chapter 14. Landslide Susceptibility Evaluation And Analysis: A Review On Articles Published During 2000 To 2020 -- Chapter 15. Assessment of the social impact of arsenicosis through groundwater arsenic poisoning in Maldah district -- Chapter 16. Ground water depletion zonation using Geospatial technique and TOPSIS in Raipur District, Chhattisgarh, India -- Part-II. Multi-hazards Management -- Chapter 17. Terrain Sensitivity guided and People’s Perception based Risk Area Management of the hills of Darjeeling district, India -- Chapter 18. Wastewater treatment in India- a new perspective -- Chapter 19. Adaptation to climate change in agriculture at Teesta basin in Bangladesh -- Chapter 20. Land use/Land cover change detection through the spatial approach: a case study of the Badiadka panchayath, Kerala -- Chapter 21. Application of AHP and Geospatial technology in Groundwater potentiality mapping: A Case Study from Tamil Nadu, India -- Chapter 22. Expected Climate-Induced Alterations in Sugarcane Yield Distribution and Its Agronomic Adaptation Strategies -- Index.
    Abstract: To monitor multi-hazards, Remote Sensing and GIS-based multi-criteria decision-making (MCDM) techniques have been extensively used in recent years worldwide. Since natural hazards cannot be eliminated, only quantification of these events and reliable forecasting can alleviate their detrimental effects, through which we can build more resilient and safe societies. Moreover, cultivating the proper knowledge of the multi-hazards and their monitoring and management can fill the gap between science, policy, and the community concerned. In an endeavor to understand and characterize the various hazards, Monitoring and Managing Multi-hazards: A Multidisciplinary approach presents a synthesis of what cross-disciplinary researchers know about these hazards and indigenous adaptation strategies. The book therefore focuses on the use of precision techniques, Remote Sensing, and GIS technologies to quantify various natural, environmental and social hazards along with the capacity building and sustainable mitigation strategies towards resilient societies. It encompasses both thematic and regional case studies to highlight the dynamicity of climate change, change of natural resources, landscape, water, river, agricultural, and social ecosystems at various spatio-temporal scales, including theoretical and applied aspects. The book gives readers an overview and analysis of traditional and advanced geospatial technologies on atmospheric, lithospheric, hydrosphere, biospheric and socio-economic contexts, on all spatial and temporal scales regarding hazards and disasters and sustainable development and management for the future.
    Type of Medium: Online Resource
    Pages: XXXII, 344 p. 156 illus., 146 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031153778
    Series Statement: GIScience and Geo-environmental Modelling,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Water. ; Hydrology. ; Geomorphology. ; Geotechnical engineering. ; Geology. ; Water. ; Geomorphology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Part I: Karst hydrogeology and methods to study karst aquifers -- Initiative to select, label and protect the world’s most important karst springs -- Flood hazard in the Classical Karst: the case of Mucille polje (NE Italy) -- Impacts of Recharge and Discharge on Sustainability of the Trinity Aquifers of Central Texas -- Hydrodynamic characterization of sources of karst: case of the source of Ain Sebou (middle Atlas, central, Morocco) -- Surprising time lag between precipitation and groundwater levels in a karst aquifer of Kopa Mt. (Slovakia) -- Updating the water budget of the Gran Sasso carbonate fractured/karstified aquifer (Central Italy) for a sustainable management of groundwater resources -- Combining quantitative analysis tools (cross-correlation analysis and dye tracer tests) to assess response times in karst aquifers -- Quantitative and Geochemical Characterization of the Mokra Karst Aquifer (SE Serbia) by Time Series Analysis and Stochastic Modelling -- Characterization of the isotopic signature of effective rainfall (δ18O, δ2H) to constrain the groundwater re-charge zones in a Mediterranean karst aquifer -- Application of statistical approaches to piezometry to improve the understanding of the karst aquifer hydrodynamic behavior at the Cadarache CEA center (France) -- Characterization of hydrogeological processes of karst-influenced multi-layered aquifers of basin edge using statistical and geochemical approaches (northern Aquitaine basin, France) -- Implications of Tryptophan-Like-Fluorescence long term monitoring for bacterial detection in a mountainous rural karst aquifer -- What microbial signature means in terms of groundwater dynamics, vulnerability and residence time – Comparison of shallow and deep karst resources -- Deriving major ion concentrations at high resolution from continuous electrical conductivity measurements in karst systems -- ydrogeological characterization and modeling at two test sites of the Apulian karst (Southern Italy) -- Prediction of future interactions between karst and river regarding to climate change based on IPCC scenarios: application to a Mediterranean french river basin (Cèze) -- A smart analytical and numerical interpretation of injection tests in unsaturated, fractured and karstified carbonate reservoirs -- On the choice of performance metric for model calibration scheme using discharge age-information -- Understanding water table fluctuations in a karstic semiarid Mediterranean aquifer through numerical modelling: the case of Almudaina-Segaria aquifer -- Part II: Karst caves, geomorphology, landscape and natural heritage -- Understandig karst conduit size distribution by numerical speleogenesis modeling -- Unroofed cave – an underground form on the karst surface -- Study of Rull Cave dynamics to understand the complex relationships between soil, cave and external atmosphere -- Hydrological and environmental dynamics in the Güixas show cave: tourist exploitation and flood risk management -- Understanding morphosedimentary changes and extreme past floods: the case of Ojo de Valjunquera cave (Iberian Range, Spain) -- Identification of near-surface karst cavities using the posterior population expansion inverse method applied to electrical resistivity data -- Use of terrestrial LiDAR scanner for monitoring of ice thickness in ice caves; examples from Slovenia -- Evidences of past and present cave hypogenesis in the Serrezuela de Carratraca Massif (Málaga, Southern Spain) -- Microstratigraphic analysis of a speleothem from the Nerja Cave (Málaga, Southern Spain) -- Gypsum dissolution rate, new data and challenges -- A Multidisciplinary investigation of karstic subsidence in a Madrid urbanization #148 -- Morphometric comparison of dolines in three karst landscapes developed on different lithologies -- The importance of snow in the hydrogeology of a high relief karst system: Sierra de Tendeñera, in the Pyrenees Mountain range (Huesca, Northern Spain) -- The link between man and water in karst, through examples from Apulia (S Italy) -- Hydrogeological setting of Las Loras UNESCO Global Geopark (Palencia-Burgos, Spain): State of knowledge and needs for water resources sustainability research -- Preliminary hydrogeological investigations for sustainable development in the Courel Mountains UNESCO Global.
    Abstract: This book covers advances in the field of karst from a variety of perspectives to facilitate knowledge and promote interaction between disciplines. New methods are addressed that advance data collection, analysis, and interpretation in a wide range of karst contexts. Case studies are presented to provide examples of advancing science. Issues addressed include karst hydrogeology (water resources assessment, groundwater pollution and protection), methods to study karst aquifers (based on hydrodynamic, hydrochemistry, isotopes, dye tracing, geophysical surveys, and modeling techniques), karst geomorphology and landscape, mining and engineering in karst media (tunnels, dams, etc.), and karst cavities (touristic caves, natural heritage). This book is a resource for scientists around the world to compare problems, results, and solutions. Likewise, the examples included are used in policy decision making in karst regions. Finally, the contributions are used as a tool for university teaching.
    Type of Medium: Online Resource
    Pages: XIII, 254 p. 170 illus., 163 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031168796
    Series Statement: Advances in Karst Science,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Keywords: Neurosciences. ; Zoology. ; Neuropsychology. ; Neuroscience. ; Zoology. ; Neuropsychology.
    Description / Table of Contents: 1 The search for the nature of the soul -- 2 The functional neuroanatomy of the limbic system -- 3 Neuro- and psychopharmacology -- 4 Neurophysiology -- 5 Developmental neurobiology -- 6 Emotion, motivation, personality and their neurobiological foundations -- 7 Neurobiological consequences of early stress experiences -- 8 Psychological and neurobiological foundations of consciousness -- 9 Nature, diagnosis and classification of mental illness -- 10 Psyche and mental illness - addiction -- 11 Psychotic illness ("schizophrenia") -- 12 Affective disorders using the example of unipolar depression -- 13 Anxiety disorders -- 14 Neuropsychotherapy - psychotherapy methods and their effects -- 15 Psychoneuroscience and its significance for practice. .
    Abstract: The textbook builds a bridge between the "neurosciences" (theoretical and experimental neurobiology, neurology) and the "psychosciences" (psychology, psychiatry, psychotherapy) and aims to help provide the other disciplines with the most important and scientifically validated knowledge in an understandable form. The question of how mental experience and brain processes relate to each other has long been considered mysterious. In this book you will learn, based on the latest scientific findings, that the two areas form an indissoluble unity, even if we experience and study them differently. We present this unity in concrete terms in psychological-neurobiological theory and psychiatric-psychotherapeutic practice. We treat the principles of neurobiological excitation and information processing, the structure and function of the limbic system, the development of the personality and the interaction of genetic-epigenetic factors and prenatal and postnatal environmental influences, which may be favourable or unfavourable. On this basis, the exemplary presentation of important mental disorders such as addictive disorders, schizophrenic disorders, affective disorders and anxiety disorders takes place. Finally, following in the footsteps of the eminent psychotherapist Klaus Grawe, the concept of "neuropsychotherapy" is introduced and it is shown why psychiatry-psychotherapie and neurobiology belong together and can enrich each other. Our psychoneuroscientific approach paints a picture of man that is not based on opposites, but on an integration of psyche, brain, behavior and experience. The editors Prof. Dr. phil. Dr. rer. nat Gerhard Roth researches and teaches at the Institute for Brain Research, University of Bremen. "Psyche, personality and brain form an inseparable unit, even if we experience them differently". Prof. Dr. med. Dr. phil. Andreas Heinz is Clinic Director at the Department of Psychiatry and Psychotherapy at Charité Berlin. "The interplay of neurobiology, behavior and subjective experience is illuminated by new methods and models." Prof. Dr. med. Dr. phil. Henrik Walter heads the research area "Mind and Brain" at the Department of Psychiatry and Psychotherapy at Charité Berlin and is the deputy medical director of the clinic. "Neuroscience education in the practice of psychiatry and psychotherapy is increasingly becoming a matter of course - and that's a good thing." This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.
    Type of Medium: Online Resource
    Pages: XIV, 371 p. 61 illus., 57 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783662657744
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Medical genetics. ; Bioinformatics. ; Neuroscience. ; Medical Genetics. ; Bioinformatics. ; Computational and Systems Biology.
    Description / Table of Contents: 1-Attitudes and smoking prevalence among undergraduate students in central Greece -- 2-Care of patients with Alzheimer’s disease -- 3-Regulation of antioxidant enzymes levels in rat brain -- 4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy -- 5-Cerebral critical closing pressure at concomitant traumatic brain injury -- 6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias -- 7-The Development of Antisense RNA Treatments using Engineered Protein Substrates -- 8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases -- 9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma -- 10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study -- 11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients -- 12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial -- 13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents -- 14-Stress system activation analysis in Greek female adolescents: a bioimpedance study -- 15-Kisspeptin and the genetic obesity interactome -- 16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis -- 17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia -- 18-Ebola virus disease and current therapeutic strategies; A review -- 19-Hyperbaric Oxygen Therapy effect on “Kinesia Paradoxa” Brain Circuits -- 20-Early and Very Early GRIM19 and MCL1 Expression are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line -- 21-Phospholipid Fatty Acid Profile of Spirulina platensis -- 22-Chronic systemic inflammation measured by bioimpedance technology before and after sleeve gastrectomy: a feasibility study -- 23-Synthesis and Biological Evaluation Substituted Thiophene Derivatives -- 24-Force spectroscopy in mechanical protein domains unfolding -- 25-Investigating the genetic component of Parkinson’s Disease -- 26-Urticaria from the Neurodermatological Perspective: A Temporal Analysis of Urticaria and Cognition -- 27-Novel Low-Noise CMOS Bioamplifier for the Characterization of Neurodegenerative Diseases -- 28-The Kentucky Inventory of Mindfulness Skills in Greek Undergraduate and Postgraduate Students -- 29-Synthesis, in silico stuiesand biological evaluation of 1, 3 ,4 oxadiazino indole derivatives -- 30-Designing and screening of new schiff bases of indole derivatives for anti-bacterial activity by in-silico methods and docking studies -- 31-Use of vitamin D bolus in fortified juice for improving vitamin D status in children with Cerebral Palsy -- 32-Microbes and the games they play -- 33-Impurity Profiling and Identification of 2,6 diisopropylphenol by Raman spectroscopy -- 34-Cultural Accommodation of the Strengthening Families Program for Parents and Young Adolescents 10-14: Greek Phase I & II Study -- 35-The effect of nutrients on Alzheimer’s disease biomarkers: A metabolomic approach -- 36-The impact of exercising in the quality of life of people with Aementia-Alzheimer disease -- 37-Advanced Health Technologies and Nanotechnologies in Neurodegenerative Diseases -- 38-Phenotype and genotype study in a case of frontometaphyseal dysplasia 1 -- 39-Craniofacial and neurological phenotype in a case of oculodentodigital syndrome -- 40-Clinical and molecular study of common thrombophilia mutation prothrombin G20210A -- 41-Prenatal genetic testing for X-linked hypohidrotic ectodermal dysplasia -- 42-Preimplantation genetic testing for spastic paraplegia type 3 -- 43-Synthesis, anti-inflammatory activity and in-silico studies of some new 3-({P-DIMETHYLAMINO}BENZYLIDENE YDRAZINYLIDENE)-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES -- 44-Design, characterization and docking studies of some novel isatin derivatives for anticonvulsant and antidepressant activity -- 45-Skin mirrors Brain: A Chance for Alzheimer’s Disease Research -- 46-Mitochondrial homeostasis in neurodegeneration and ageing -- 47-The Alzheimer's Disease Chronicles: will evidence triumph over adversity? -- 48-Liposomes: Production Methods and Application in Alzheimer’s Disease -- 49-Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision -- 50-Biomarkers and Precision Medicine in Alzheimer’s Disease -- 51-The role of microRNAs in thrombosis -- 52-Photo-oxygenation: an innovative new therapeutic approach against amyloidoses.
    Abstract: The 5th World Congress on Genetics, Geriatrics, and Neurodegenerative Diseases Research (GeNeDis 2022) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. This volume focuses on the sessions from the conference on Neuroscientific Advances.
    Type of Medium: Online Resource
    Pages: XXXI, 673 p. 58 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031319860
    Series Statement: Advances in Experimental Medicine and Biology, 1425
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurology . ; Nanowires. ; Neuropharmacology. ; Neuroscience. ; Neurology. ; Nanowires. ; Neuropharmacology.
    Description / Table of Contents: Section I: Neurodegenerative diseases -- Chapter 1: Nanowired delivery of cerebrolysin together with antibodies to amyloid beta peptide, phosphorylated tau and tumor necrosis factor alpha induces superior neuroprotection in Alzheimer's disease brain pathology exacerbated by sleep deprivation -- Chapter 2: Nanodelivery of histamine H3/H4 receptor modulators BF2649 and clobenpropit with antibodies to amyloid beta peptide in combination with alpha synuclein reduces brain pathology in Parkinson's disease -- Chapter 3: Co-administration of nanowired DL-3-n-butylphthalide (DL-NBP) together with mesenchymal stem cells, monoclonal antibodies to alpha synuclein and TDP-43 (TAR DNA-binding protein 43) enhance superior neuroprotection in Parkinson's disease following concussive head injury -- Chapter 4: Neuroprotective effects of nanowired delivery of cerebrolysin with mesenchymal stem cells and monoclonal antibodies to neuronal nitric oxide synthase in brain pathology following Alzheimer’s disease exacerbated by concussive head injury -- Section II: Central Nervous system Trauma -- Chapter 5: Co-administration of nanowired monoclonal antibodies to inducible nitric oxide synthase and tumor necrosis factor-alpha together with antioxidant H-290/51 reduces SiO2-nanoparticles induced exacerbation of pathophysiology of spinal cord trauma -- Chapter 6: Nanowired delivery of cerebrolysin with mesenchymal stem cells attenuates heat stress induced exacerbation of neuropathology following brain blast injury -- Chapter 7: Co-administration of nanowired oxiracetam and neprilysin with monoclonal antibodies to amyloid beta peptide and p-tau thwarted exacerbation of brain pathology in concussive head injury at hot environment -- Section III. Stress and Drugs of abuse -- Chapter 8: Nanowired delivery of mesenchymal stem cells with antioxidant compound H-290/51 reduces exacerbation of methamphetamine neurotoxicity in hot environment -- Chapter 9: TiO2-nanowired delivery of Chinese extract of Gingko biloba EGb-761 and bilobalide BN-52021 enhanced neuroprotective effects of cerebrolysin following spinal cord injury at cold environment -- Chapter 10: Nanowired delivery of curcumin attenuates methamphetamine neurotoxicity and elevates levels of dopamine and brain derived neurotrophic factor.
    Abstract: This book covers the use of nanomedicine in the delivery of neuroprotective agents, including pharmacological drugs, stem cells, neurotrophic factors, monoclonal antibodies and enzymes to induce greater beneficial effects in neurologic diseases. Thus, the main purpose of the book is to explore the delivery of drugs either alone or in combination with stem cells to enhance neuroprotection in neurological diseases. Brain pathology associated with acute trauma such as head injury and brain blast injury can also be managed using novel treatment strategies. In addition, emphasis is made that standard patterns of brain pathology may be complicated with multiple comorbidity factors where one agent alone is not sufficient to induce brain protection. Enzymes and antibodies may help in combination and enhance the efficacy when administered through nanotechnology. Progress in Nanomedicine in Neurologic Diseases will encourage further research in the field of neuroprotection, brain injury, neurodegenerative diseases, neuropharmacology, neuropathology, and neurology. Students and researchers along with policy makers, teachers and health care professionals may also benefit from the findings of the book for enhanced patients care.
    Type of Medium: Online Resource
    Pages: XV, 418 p. 40 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031329975
    Series Statement: Advances in Neurobiology, 32
    DDC: 612.8
    Language: English
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    Keywords: Neurosciences. ; Developmental biology. ; Nervous system Diseases. ; Neuroscience. ; Developmental Biology and Stem Cells. ; Neurological Disorders.
    Description / Table of Contents: Chapter 1. History, origin and types of neurological disorders -- Chapter 2. Mechanistic approach involved in the progression of Neurodegenerative disorders -- Chapter 3. Isolation, characterization and differentiation of stem cells -- Chapter 4. Role of Stem cells as a protective agent against neurological complications -- Chapter 5. Mesenchymal stem cells and their application against neurodegenerative disorders -- Chapter 6. iPSCs and their role in amelioration of neurodegenerative disorders -- Chapter 7. Isolation, characterization and detailed history of exosomes derived from stem cells and their epigenetic biology -- Chapter 8. Stem cells vs exosomes: promising therapeutic approach and biomarkers agent against neurodegenerative disorders -- Chapter 9. Role of stem cells and derived exosomes as a novel therapeutic agent against neuroinflammation and stroke -- Chapter 10. Role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer’s and Parkinson's disease -- Chapter 11. Role of stem cells and derived exosomes and associated signalling molecules involved in neuroprotection -- Chapter 12. Exosome as nanoparticles against neurodegenerative disorders.
    Abstract: This book explores the therapeutic approaches of stem cells and stem cell-derived exosomes against neurodegenerative disorders (NDDs). The initial chapters introduce different neurodegenerative diseases and discuss the mechanistic aspects of their progression. The subsequent chapters cover strategies for the isolation, characterization, and differentiation of stem cells. In turn, the book reviews the protective role of stem cells against neurological disorders and examines regenerative approaches to treat neurological diseases using mesenchymal stem cells. The book also presents induced pluripotent stem cell (iPSC) technology for cellular therapy, drug screening, and in-vitro modeling of neurodegenerative diseases. Lastly, the book discusses the role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer's and Parkinson's disease and in associated signaling molecules involved in neuroprotection. This book is an invaluable source for researchers working towards understanding the potential of stem cell therapy in neurodegenerative disorders.
    Type of Medium: Online Resource
    Pages: XIII, 327 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819938483
    DDC: 612.8
    Language: English
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  • 46
    Keywords: Neurosciences. ; Computational neuroscience. ; Biophysics. ; Science History. ; Neuroscience. ; Computational Neuroscience. ; Biophysics. ; History of Science.
    Description / Table of Contents: 1. Integrate and fire: RC circuits to model neurons and reward monkeys -- 2. Neuronal spike trains, stochastic point processes, and why George Gerstein’s papers are still worth reading -- 3. Visual Functions of Inferior Temporal Cortex -- 4. Early Days in the Gerstein Lab: Neuronal Plasticity in 1, 2, and 3 Dimensions -- 5. Patterns in Spike Trains -- 6. Introduction to the Gravity Papers -- 7. On correlations and interactions between neurons and with George Gerstein -- 8. Significance of Correlations between Spike Trains -- 9. Spatial-Temporal Spike Patterns -- 10. Does Cross Correlation Have a Unique Interpretation? -- 11. Neuronal Plasticity and my Experience Working with George L. Gerstein -- 12. Auditory Experiments and Modeling -- 13. Thinking about Analysis Methods with George in Philadelphia, Cambridge and Newcastle -- 14. Higher-order Correlations and Synfire Chains -- Nencki Award for George L. Gerstein.
    Abstract: This book brings together a selection of papers by George Gerstein, representing his long-term endeavor of making neuroscience into a more rigorous science inspired by physics, where he had his roots. Professor Gerstein was many years ahead of the field, consistently striving for quantitative analyses, mechanistic models, and conceptual clarity. In doing so, he pioneered Computational Neuroscience, many years before the term itself was born. The overarching goal of George Gerstein’s research was to understand the functional organization of neuronal networks in the brain. The editors of this book have compiled a selection of George Gerstein’s many seminal contributions to neuroscience--be they experimental, theoretical or computational--into a single, comprehensive volume .The aim is to provide readers with a fresh introduction of these various concepts in the original literature. The volume is organized in a series of chapters by subject, ordered in time, each one containing one or more of George Gerstein’s papers.
    Type of Medium: Online Resource
    Pages: XIII, 548 p. 253 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783030874476
    Series Statement: Springer Series in Computational Neuroscience,
    DDC: 612.8
    Language: English
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  • 47
    Keywords: Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Description / Table of Contents: Soundscape – The Development of a New Discipline -- Soundscape: A Construct of Human Perception -- Soundscape: The Holistic Understanding of Acoustic Environments -- Soundscape and Urban Planning -- Architectural Soundscapes: Theories, Methods, and Practice -- Psychoacoustics in Soundscape Research -- Measurements and Techniques in Soundscape Research -- Triangulation as a Tool in Soundscape Research -- Soundscape and Health -- Hospital Soundscape -- How to Put Soundscape into Practice.
    Abstract: The concept of “Soundscape” includes all sounds in an environment and focuses on the interrelationship between person, activity and place, both in space and time. The goal of this volume is to present and review the developments in the field of Soundscape, reflecting standardization procedures and diverse applications. Soundscape – The Development of a New Discipline Brigitte Schulte-Fortkamp, and André Fiebig Soundscape: A Construct of Human Perception André Fiebig Soundscape: The Holistic Understanding of Acoustic Environments Brigitte Schulte-Fortkamp and Pamela Jordan Soundscape and Urban Planning Bennett M. Brooks Architectural Soundscapes: Theories, Methods, and Practice Gary W. Siebein, and Keely M. Siebein Psychoacoustics in Soundscape Research Klaus Genuit, Brigitte Schulte-Fortkamp, and André Fiebig Measurements and Techniques in Soundscape Research Giovanni Brambilla, and André Fiebig Triangulation as a Tool in Soundscape Research Dick Botteldooren, Bert De Coensel, and Francesco Aletta, Jian Soundscape and Health Peter Lercher, and Angel M. Dzhambov Hospital Soundscapes Ilene Busch-Vishniac, and Erica Ryherd How to Put Soundscape into Practice André Fiebig, andBrigitte Schulte-Fortkamp .
    Type of Medium: Online Resource
    Pages: XVII, 330 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031227790
    Series Statement: Springer Handbook of Auditory Research, 76
    DDC: 612.8
    Language: English
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  • 48
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nervous system Diseases. ; Developmental neurobiology. ; Cognitive neuroscience. ; Neuroscience. ; Neurological Disorders. ; Development of the Nervous System. ; Cognitive Neuroscience.
    Description / Table of Contents: PART I. Iron, Brain Function and Behavior -- Chapter 1. Iron and Neuro-cognition -- Chapter 2. The Interplay Between Iron and Oxidative Stress in Brain Neurodegenerative Diseases -- Chapter 3. Specific Nutritional Therapeutic Approaches Targeting Iron Overload and Other Hallmarks of Brain Degenerative Diseases -- Chapter 4. Mediterranean Diet and Neuro-Cognition: Focus on Alzheimer disease -- PART II Brain disorders related to Iron -- Chapter 5. The Critical Roleplay of Iron Neurochemistry in Progression of Parkinson’s Disease -- Chapter 6. Iron-Calcium Crosstalk in Neurodegenerative Diseases -- Chapter 7. Iron and Alzheimer’s Disease -- Chapter 8. Iron and Multiple Sclerosis -- Chapter 9. Iron and Epilepsy -- Chapter 10. Iron and Subarachnoid Hemorrhage -- Chapter 11. Iron deficiency and psychiatric disorders -- Chapter 12. Iron and Neuro-developmental Disorders -- Chapter 13. Iron and Neuropathies.
    Abstract: This book explores the molecular mechanisms of iron hemostasis in the brain and discusses the cognitive and behavioral implications of iron deficiency. It presents the effect of iron dysregulation on neurophysiological mechanisms. The book provides an overview of iron metabolism and homeostasis at the cellular level and its regulation at the mRNA translation level. It emphasizes the importance of iron for brain development in fetal and early life in preterm infants. Further, it presents iron metabolism as a therapeutic target for novel pharmacological treatment against neurodevelopmental diseases and neurodegenerative disorders. It discusses the role of iron deficiency in sleep disorders and offers diagnosis and treatment of iron-related CNS diseases. Finally, it relates dysregulated expression of iron-related genes in brain tumors.
    Type of Medium: Online Resource
    Pages: XX, 280 p. 10 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811973277
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 49
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Cytology. ; Zoology. ; Neurology . ; Neuroscience. ; Cell Biology. ; Zoology. ; Neurology.
    Description / Table of Contents: The Architecture of the Presynaptic Release Site.-Cytomatrix Proteins in Presynaptic Terminal. - Multiple Modes of Fusion and Retrieval at the Calyx of Held Synapse -- Roles of SNARE Proteins in Synaptic Vesicle Fusion -- Calcium Sensors of Neurotransmitter Release. - Roles and Sources of Calcium in Synaptic Exocytosis -- Regulation of Presynaptic Calcium Channels -- Roles of mUnc13/UNC-13 and mUnc18/UNC-18 in Neurotransmitter Release. - The role of tomosyn in the regulation of neurotransmitter exocytosis. -Roles of complexins in Neurotransmitter Release. -Regulation of Neurotransmitter Release by AIPR-1/AIP and calstabins. - The Role of Potassium Channels in the Regulation of Neurotransmitter Release -- Roles of Neuropeptides in Synaptic Function. - Transsynaptic Regulation of Presynaptic Release Machinery in Central Synapses by Cell Adhesion Molecules. - Lipids and Secretory Vesicle Exocytosis -- Synaptic Vesicle Endocytosis.
    Abstract: Neurons communicate with each other by releasing neurotransmitters. This book provides comprehensive coverage of the molecular mechanisms involved in neurotransmitter release. The topics covered in the book range from the architecture and cytomatrix proteins of presynaptic sites, to the modes of synaptic vesicle exocytosis (full-collapse and kiss-and-run), and from the key molecules mediating synaptic vesicle fusion (SNAREs) to those that closely interact with them (UNC-13/Munc13, UNC-18/Munc18, tomosyn, and complexins). The book also delves into the calcium sensors of synaptic vesicle fusion (synaptotagmins and Doc2s), the sources of calcium that trigger synaptic exocytosis (voltage-gated calcium channels and ryanodine receptors), and the regulation of neurotransmitter release by potassium channels, cell adhesion molecules, lipids, aryl hydrocarbon receptor-interacting protein (AIP), presenilins, and calstabins. To aid in understanding and illustrate key concepts, the book includes sufficient background information and a wealth of illustrations and diagrams. The new edition includes major updates to previous chapters, as well as several new chapters that reflect the recent advances in the field. Comprehensive and cutting-edge, Molecular Mechanisms of Neurotransmitter Release, 2nd edition, is a valuable learning resource for neuroscience students and a solid reference for neuroscientists.
    Type of Medium: Online Resource
    Pages: XI, 401 p. 77 illus., 62 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031342295
    Series Statement: Advances in Neurobiology, 33
    DDC: 612.8
    Language: English
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  • 50
    Keywords: Neurosciences. ; Cytology. ; Ecology . ; Neural circuitry. ; Neuroscience. ; Cell Biology. ; Ecology. ; Neural Circuits.
    Description / Table of Contents: 1. Introduction -- 2. Diversity and evolution of jellyfish visual systems, Mollusks -- 3. Scallops distributed eyes -- 4. Chiton dispersed visual systems, Annelids -- 5. Errant polychaetes Arthropods -- 6. Spider eyes -- 7. Myriapod eyes -- 8. Insect ocelli -- 9. Batflies, copepods or larval stomatopods -- 10 -- Hyperiid amphipods, Echinoderms -- 11. Brittle star vision -- 12. Starfish vision.
    Abstract: This volume explores the diversity of distributed eyes and other unusual visual systems in nature. It compares the unique themes of optics, neural processing, and behavioral control that emerge from these visual systems with more-canonical eyes. This volume attempts to answer a number of questions about distributed visual systems. What are distributed visual systems good for, how do they function, and why have they arisen independently in so many phyla? Why are eye designs and visual system arrangements much more diverse in invertebrates? Each chapter includes an overview of the visual systems that exist in their group of animals, relates vision to ecology, and takes a comparative approach. .
    Type of Medium: Online Resource
    Pages: VII, 320 p. 70 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031232169
    Series Statement: Springer Series in Vision Research,
    DDC: 612.8
    Language: English
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  • 51
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: Editorial -- Dystonia in childhood - how insights from paediatric research enrich the network theory of dystonia -- Focal Dystonia and the Stress-Network -- Limbic influences in Musicians dystonia -- Network perspective on task-specific dystonia -- Electromyography as a method for distinguising dystonia-like behavior in mice -- Deep brain stimulation of the interposed cerebellar nuclei in a mouse model of dystonia -- Applications of Transcranial Magnetic Stimulation for understanding and treating dystonia -- Brain connectivity in dystonia: evidence from Magnetoencephalography -- Dysfunctional networks in functional dystonia -- Collicular-pulvinar-amygdala axis and adult-onset idiopathic focal dystonia syndrome -- Neuromodulation in dystonia -- Electrophysiological properties of pallidal cells in cervical dystonia patients undergoing unilateral DBS -- Clinical implications of dystonia as a neural network disorder.
    Abstract: A recently proposed novel scheme of dystonia suggests that it is a disorder of neural network. Impairment in any of the “nodes” of the network may result in deficient network activity, causing dystonia. This book aims to present various experimental evidence supporting the network theory of dystonia. Dystonia is the abnormal twisting and turning of the organ and associated involuntary oscillations. Although dystonia is less common than Parkinson’s disease, traumatic brain injury, or stroke, each of these common disorders present with dystonia. Information regarding the brain regions that may be involved in dystonia is surprisingly limited and often conflicting. With chapters written by subject matter experts, this is a unique title that focuses on dystonia as a network disorder. This book would be of interest to basic and clinical researchers with an interest in motor systems and movement disorders.
    Type of Medium: Online Resource
    Pages: XI, 242 p. 37 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031262203
    Series Statement: Advances in Neurobiology, 31
    DDC: 612.8
    Language: English
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  • 52
    Keywords: Neurosciences. ; Neurology . ; Nervous system Diseases. ; Cognitive neuroscience. ; Neurophysiology. ; Learning Physiological aspects. ; Memory Physiological aspects. ; Neuroscience. ; Neurology. ; Neurological Disorders. ; Cognitive Neuroscience. ; Neurophysiology. ; Learning and Memory.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings -- Chapter 3. Alzheimer’s Disease Research After 1945: The Recommencement -- Chapter 4. Alzheimer’s Research Goes Deeper – Ultrastructural Electron Microscopy Studies -- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer’s Disease -- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer’s Disease -- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer’s Disease -- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor -- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer’s Disease -- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals -- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas? -- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis -- Chapter 13. Focus on Tauopathies and Beyond -- Chapter 14. Alzheimer’s Research Gains Momentum and Spreads Out -- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally -- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way -- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias? -- Chapter 19. Driving Forces of Alzheimer’s Research Directions -- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last? -- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change".
    Abstract: This book highlights the key phases and central findings of Alzheimer’s Disease research since the introduction of the label ‘Alzheimer’s Disease’ in 1910. The author, Christian Behl, puts dementia research in the context of the respective zeitgeist and summarizes the paths that have led to the currently available Alzheimer’s drugs. As the reader is taken through the major developments in Alzheimer's Disease research, particularly over the past thirty years, Behl poses critical questions: Why are the exact causes of Alzheimer's Disease still in the dark, despite all the immense, worldwide research efforts in academia as well as in the pharmaceutical industry? Why has the majority of an entire research field kept focusing on a single hypothesis that establishes the deposition of the amyloid beta peptide in the brain as the key trigger of Alzheimer's pathology, even though this concept has still not been convincingly proven in the clinics? Are there other hypotheses that might explain the pathogenesis of this complex brain disease, and if so, why were these perspectives not adequately followed? In this book, Behl tries to answer these questions. Starting with the historical background, the author illustrates the long and arduous research journey, its numerous setbacks, and the many alternative explanations for the disease, which have started gaining increasing attention and acceptance in the Alzheimer’s research community only more recently. With his deep dive into the history and progression of this research, including the most recent developments, Behl explains why he believes that it is high time to promote a paradigm shift in Alzheimer’s Disease research. The book is written for all researchers in the fields of neurobiology and neurodegeneration, as well as other biomedical fields, who would like to gain a broad and beyond the surface insight into (the key developments of) one of the most promoted research fields of our time. With its extensive literature references and over 100 illustrations, the book is also attractive for students and interested lay persons. Elaborating on all the different aspects and research approaches of this research field, the author aims to convince the reader that the underlying causes of Alzheimer’s Disease may be much more complex than previously thought and that this must be considered for future research directions. While he hopes that the Alzheimer’s research community is finally ready to shed its ‘amyloid-straitjacket’ that has hampered progress for too long, he is also convinced that a much-needed paradigm shift can guide future Alzheimer’s Disease research and provide a new and broader perspective on this age-dependent brain disease.
    Type of Medium: Online Resource
    Pages: XXV, 652 p. 116 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315701
    DDC: 612.8
    Language: English
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    Keywords: Neurosciences. ; Immunology. ; Ophthalmology. ; Neuroscience. ; Immunology. ; Ophthalmology.
    Description / Table of Contents: High Resolution Imaging Mass Spectrometry of Human Donor Eye: Photoreceptor Cells and Basal Laminar Deposits of Age-related Macular Degeneration -- The non-canonical role of Complement Factor H in Retinal Pigment Epithelium (RPE) cells and implications for Age-related Macular Degeneration -- Macular Pigment Carotenoids and Bisretinoid A2E -- Disturbed matrix metalloproteinases activity in age-related macular degeneraton -- Current views on Chr10q26 contribuiton to age-related macular degeneration -- Untargeted lipidomic profiling of aged human retina with and without age-related macular degeneration (AMD) -- Decoding Race and Age-Relation Macular Degeneration: GPR 143 Activity is the Key -- Peroxisome proliferator-activated receptor gamma coactivator 1 alpha ( PGC-1x): a transcriptional regulator at the interface of aging and age-related macular degeneration? -- Regulation of ABCA1 by miR-33 and miR-34a in the aging eye -- The role of gene expression regulation on genetic risk of Age-related Macular Degeneration -- Elastin layer in Bruch's membrane as a target for immunizatio or tolerization to modulate patthology in the mouse model of somke-induced ocular injury -- Repuprosing drugs for treatment of age-relation macular degeneration -- Extracellular Vesicle RNA Contents as Biomarkers for Ocular Diseases -- Proteomics of retinal extracellular vesicles: a reviw inot an unexplored mechanism in retinal health and AMD pathogenesis -- Prime Editing Strategy to Instally the PRHP2 c.828+1G A mutations -- Analysis of CRB1 Pathogenic Variants Correctable with CRISPR Base and Prime Editing -- Generation of an Avian Myeloblastosis Virus (AMV) Reverse Transcriptase Prime Editor -- Pre-existing neutralizing antibodies against different adeno-associated virus serotypes in humans and large animal models for gene therapy -- Optimization of Capillary-based Western Blotting for MYO7A -- AAV Serotypes and Their Suitability for Retinal Gene Therapy -- Gene Augmentation ofautosomal dominant CRX-associated retinopathies -- Txnip gene therapy of retinitis pigmentosa improves cone health Factors affecting readthrough of natural versus premature termination codons -- Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease -- Network biology and medcine to resuce: Applications for retinal disease mechanisms and therapy -- Non-sydromic Retinal Degeneration Caused by Pathogenic Variants in Joubert Syndrome Genes -- Exonic variants that affect splicing- an opportunity for "hidden" mutations causing inherited retinal diseases -- Enhanced S-cone Syndrome, a Mini-Review -- The role of microglia in Inherited Retinal Diseases -- CD68: potential contributor to inflammation and RPE cell dystrophy -- Gene Expression of Clusterin, Tissue Inhibitor of Metalloproteinase-1, and Their receptors in Retinal Pigment Epithelial Cells and Muller Glial Cells is Modulated by Inflammatory Stresses -- Axonal Transport Defects in Retinal Ganglion Cells -- Connexins biology in the pathophysiology of retinal diseases -- Role of Nuclear NAD +in Retinal Homeostasis -- Retinal pigmented epithelium-derived ectopic norrin does not promote intraretinal angiogenesis in transgenic mice -- Caveolin-1 Muller glia exist as heat-resistant,high molecular weight complexes -- Role of VLC-PUFAs in Retinal and Macular Degeneration -- Ocular amyloid , condensates, and aggregates - higher order protein assemblies participate in both retinal degeneration and function -- Photoreceptor ion channels in signaling and disease -- The role of peripherin-2 /ROM1 complexes in photoreceptor outer segment disc morphogenesis -- Human mutations in Arl3, a small GTPase involved inlipidated cargo delibery to the cilia cause retinatl dystropthy -- Genotype-Phenotype Association in ABCA4-Associated Retinopathy -- Retinal pathoconnectomics: A Window into Neurodegeneration -- The role of Ceramide in Inherited Retinal Disease Pathology -- Extracelluar Matix: the Unexplored Aspects of Retinal Pathologies and Regeneration -- Role of TFEB in diseases assocaited with lysosomal dysfunction -- Retinoic acid receptor -related oprhan receptors (RORs) in eye development and disease -- A novel mouse model for Late-Onset Retinal Degeneration (L-ORD) devekios RPE abnormalities due to the loss of C1qtnf5/Ctrp5 -- Comparison of mouse models of autosomal dominant retinitis pigmentosa due to P23H muations of Rhodopsin -- Compensatory Cone-Mediated Mechanisms in Inherited Retinal Degeneration Mouse Models: A Functional and Gene Expression Analsyis -- Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Sress and Promotes ER Protein Degradation in Cyclic Nucleotide-gated Channel Deficiency -- Mouse choroid proteome revisited: foucs on aging -- Morphological and functional comparison of mice models for retinitis pigmentosa -- Current Advancements in Mouse Models of Retinal Disease -- Single-cell Itrnacriptomic Profiling of Muller Glia in the rd10 Retina -- Methods for in vivo characterization of proteostatis in the mouse retina -- Absence or PRCD leads to dysregulation in lipie Homeostatis resulting in disorganizationof photorecptor outer segment structure -- Expansion Microscopy of Mouse Photoreceptro Cilia -- Rod photorecptor specific ablation of Metformin target, AMPK, in preclinical model of autosomal recessvie retinitis pigmentosa -- TLR2 is highly overexpressed in retinal myeloid cells in the rd10 mouse model of retinitis pigmentosa -- Environmental light has an essentail effrect on the diseasae expression in a dominant RPE65 mutation -- Microglia Preserve Visual Function in A Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant -- Measuring the release of lactate from wild-type and rd1 mouse retina -- Aerobic glycolysis in photorecptors supports energy demand in the absence of mitochondrial coupling -- Redox Status in Retinitis Pigmentosa -- Perspectives on retinal dolichol metabolism and visual deficits in dolichol metalbolism-associated inherited disorders -- Retinal metabolic profile on IMPG2 deficiency mice with subretinal lesions -- Glutathione-coating of liposomes enhances the delivery of hydrophillic cargo to the inner nuclear layer in retinal cultures -- Modification of Mueller glial cell fate and proliferation with the use of small molecules -- A potential neuroprotective role for pyruvate kinase 2 in retinal degeneration -- Critical role of VEGF as a direct regulator of photorecptor function -- Lysine Ubiquitylation Drives Rhodopsin Protein Turnover -- In-silico prediction of MYO!C Rhodopsin Interactions and its Significance in Protein Localization and Visual Function -- A ciliary branched actin netowrk drives photoreceptor disc morphogenesis -- Revisiting the daily timing of POS phagocytosis -- Inhibition of Bacterial Peoptidoglycan Cytopahty by Retina Pigment Epithelial PGRP2 Amidase -- Understanding ischemic retinopathies: the role of Succinate and its recpto^T mutation -- Inducing neural regeneratio nfrom glia using proneural bHLH transcription factors.
    Abstract: This book contains the proceedings of the XIX International Symposium on Retinal Degeneration. A majority of those who spoke and presented posters at the meeting contributed to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium focused on the exciting new developments aimed at understanding these diseases and providing therapies for them. These retinal degeneration symposia are known by most as the “best” and “most important” meetings in the field. The volume presents representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy. We anticipate that the excitement of those working in the field and those afflicted with retinal degenerations is reflected in the volume.
    Type of Medium: Online Resource
    Pages: XIX, 588 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031276811
    Series Statement: Advances in Experimental Medicine and Biology, 1415
    DDC: 612.8
    Language: English
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  • 54
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Neurology . ; Cognitive psychology. ; Neuroscience. ; Neurology. ; Cognitive Psychology.
    Description / Table of Contents: The world of Brain: from Aging Brain, Diseased Brain to Social Brain -- Cognitive Aging:How the Brain Ages -- Cognitive Decline Associated with Aging -- The Overview of Cognitive Aging Model -- The Emotional and Affective Disorders in Cognitive Aging -- The Mechanism of Socioeconomic Status and Stress Effects on Cognition -- The Aging Patterns of Brain Structure, Function and Energy Metabolism -- Characteristics of Brain Network during Cognitive Aging -- Biomolecular Markers of Brain Aging -- Neurobiological Mechanisms of Cognitive Decline Caused by Brain Aging -- The Early Stage of Abnormal Aging: Cognitive Impairment -- The Terminal Stage of Abnormal Aging: Dementia -- The Effect of Cognitive Rehabilitation Training and Its Neuroimaging and Physiology Evidence -- Lifestyle Regulation and Its Evidence: Changes brought from Adjusting Correlative Factors of Cognitive Aging -- The Effect of Traditional Chinese Medicine on Delaying Age-related Cognitive Decline and Its Evidence.
    Abstract: This book reviews the research trends of cognitive aging and brain health from full-scale. It not only contains cognitive aging’s neurophysiological mechanism, clinical research and intervention measures, but also covers cognitive aging’s social psychological mechanism, such as the relation between old people’s motion, socioeconomic status and the cognitive aging. Through decades of research and practice, the views towards the cognitive aging process havebeen transferred from coping with cognitive decline to promoting cognitive ability. This book provides with the latest research findings and in-depth opinions of the cognitive aging and brain health, assisting researchers to grasp the theories, practice and trends of this field, and guide health-care workers to carry out the treatment and nursing for the aged.
    Type of Medium: Online Resource
    Pages: VIII, 194 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819916276
    Series Statement: Advances in Experimental Medicine and Biology, 1419
    DDC: 612.8
    Language: English
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  • 55
    Keywords: Neurosciences. ; Neurochemistry. ; Medicine Research. ; Biology Research. ; Regenerative medicine. ; Neuroscience. ; Neurochemistry. ; Biomedical Research. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: The Purinergic Signaling: Overview -- Adenosine A2A Receptor-containing Heteromers and Neuroprotection -- Purinergic Signaling in Brain Physiology -- Neurotrophic Actions of Adenosine and Guanosine: Implications for Neural Development and Regeneration? -- Purinergic Signaling in Neurogenesis and Neural Fate Determination: Current Knowledge and Future Challenges -- Purinergic Signaling in Autism Spectrum Disorder -- Purinergic Signaling in Depression -- Roles of Purinergic Receptors in Alzheimer's Disease -- Purinergic Signaling in Basal Ganglia Diseases: Parkinson's Disease -- A Step in the ALS Direction: Lessons from the Purinome -- Purinergic P2 Receptors in Epilepsy -- Purinergic Signaling in Neuroinflammation -- Purinergic Signaling in Brain Tumors -- Development of Purinergic Receptor Agonists and Antagonists -- Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation.
    Abstract: This volume explores the quickly evolving field of Purinergic signaling, and examines how receptors for ATP and other nucleotides, and receptors for adenosine, act in neuronal transmission, control of synaptic activity, proliferation, differentiation and cell death regulation in the CNS. This book focuses on the participation of purinergic receptors and ectonucleotidases, degrading ATP into adenosine, in embryonic and adult neurogenesis in vitro and in vivo as well as in synaptic transmission and pathophysiology. Further, the chapters discuss varying brain diseases, including Parkinson’s, and Alzheimer’s disease, autism, mood disorders and epilepsy, as well as brain tumors, in the context of purinergic signaling and its clinical aspects. The development of purinergic receptor agonists is also an important issue of this book. This book provides a critical review of the current state of science and will be useful for both scientists and students who are or would like to get involved in this area. Furthermore, this book addresses neuroscientists, physician and professionals from the industry, who would like to update themselves in this exciting and rapidly growing field of neuroscience.
    Type of Medium: Online Resource
    Pages: X, 376 p. 34 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031269455
    DDC: 612.8
    Language: English
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  • 56
    Keywords: Psychobiology. ; Human behavior. ; Cognitive neuroscience. ; Psychology, Experimental. ; Behavioral Neuroscience. ; Cognitive Neuroscience. ; Experimental Psychology.
    Description / Table of Contents: The promises and pitfalls of Virtual Reality -- Setting up your VR neuroscience laboratory -- Monitoring the autonomic system in VR -- Monitoring brain activity in VR: EEG and neuroimaging -- Eye-tracking and Pupillometry in VR -- VR for Movement and Action Science -- VR for Vision Science -- VR for Emotion -- VR for Thinking and Creativity -- VR for Social Cognition -- VR as a window into Consciousness -- Aging -- Learning -- Pain -- Cognitive and motor rehabilitation -- VR for Mental Health.
    Abstract: Virtual Reality (VR) is a rapidly maturing technology that offers new and unique solutions to otherwise intractable problems in the study of cognition, behavior and neuroscience. VR removes many of the constraints imposed by laboratory paradigms, allowing us to track cognitive, behavioral and brain responses to naturalistic (or even impossible) situations without sacrificing experimental control. But VR is not a tool that can be swiftly and effortlessly integrated into existing research pipelines; currently, the benefits of VR are accompanied by a host of methodological challenges and important practical considerations. To help navigate this new methodology, this volume provides a balanced review of both the exciting new findings emerging from VR labs and the challenges and limitations that are part and parcel of VR research. This volume is an important first step toward establishing a standardised methodology for conducting research in VR. To this end, the volume provides a wealth of practical advice for researchers who are new to the technology. This volume is authored by an interdisciplinary team of VR researchers including computer scientists, engineers, psychologists and neuroscientists. It highlights current research in the field to demonstrate how VR advances our understanding of the mind, while also providing groundbreaking solutions in applied domains.
    Type of Medium: Online Resource
    Pages: X, 387 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031429958
    Series Statement: Current Topics in Behavioral Neurosciences, 65
    DDC: 612.8
    Language: English
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  • 57
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geophysics. ; Physical geography. ; Geology. ; Geophysics. ; Earth System Sciences.
    Abstract: The sixth volume of “Processes in GeoMedia”, connected to the Russian journal with the same name, publishes new results of theoretical and experimental studies of the processes occurring in the bowels of the earth, the ocean, and the atmosphere; particular attention is paid to geomechanical aspects of the production of hydrocarbons, including laboriously extracted oils, and to the ecological problems of the biosphere, the human impact on the environment, methods of geophysical research are within the range of the journal interests.
    Type of Medium: Online Resource
    Pages: X, 697 p. 311 illus., 192 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031165757
    Series Statement: Springer Geology,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Natural disasters. ; Sustainability. ; Urban policy. ; Water. ; Hydrology. ; Natural Hazards. ; Sustainability. ; Urban Policy. ; Water.
    Description / Table of Contents: Part I: Urban flooding: Conceptions and approaches in the scope of Global Climate Change -- Part II: Urban floods in large Brazilian cities -- Part III: Urban floods in medium and small Brazilian cities. .
    Abstract: This contributed volume analyzes flooding scenarios in Brazilian cities using a geographic and spatiotemporal approach to explore impacts and ways to mitigate future disasters. The problem of urban flooding is growing in Brazilian cities due to the increasing number of natural disasters in the context of global climate change; this is a topic that poses challenges to urban planners and academics. Through three sections, this volume offers theoretical-conceptual, methodological and technical case studies, as well as cases that explore urban socio-environmental problems associated with flooding. Throughout the book, the concepts of risk, vulnerability and adaptation are used to explore future flood scenarios in Brazil. The integrated vision offered in this volume covers the floods themselves, evaluation of flood impacts, and the management process before, during, and after the flood event. The case studies presented here elucidate the concept of comprehensive urban flood management, offering a technical and diagnostic basis for the problem in different cities in Brazil. The present and future challenges presented by these chapters offer widely-transferable lessons that can be applied to making cities around the world more sustainable and disaster-resilient.
    Type of Medium: Online Resource
    Pages: XVIII, 436 p. 210 illus., 194 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031208980
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Geotechnical engineering. ; Sustainability. ; Natural Hazards. ; Geotechnical Engineering and Applied Earth Sciences. ; Sustainability.
    Abstract: This book provides a comprehensive and multidisciplinary approach to addressing geohazards, with topics such as social vulnerability reduction, risk prevention, institutional preparedness, and community resilience. It also introduces new technologies to study geohazards, which is important since geohazards have caused many casualties, economic losses, and damage to cultural heritage throughout human history. Despite this, the culture of risk prevention is not yet widespread, so Disaster Risk Reduction activities must focus on increasing capacities, strategies, and action plans for prevention and preparedness in local communities.
    Type of Medium: Online Resource
    Pages: XI, 507 p. 138 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031245411
    Series Statement: Advances in Natural and Technological Hazards Research, 51
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Social sciences. ; Human geography. ; Sustainability. ; Earth sciences. ; Natural Hazards. ; Society. ; Human Geography. ; Sustainability. ; Earth Sciences.
    Description / Table of Contents: Part I: Conceptualising Disaster and Risk -- Chapter 1. Hazard and Disaster Perception: Cognition, Response and Adaptation -- Chapter 2. Characterising Hazard and Disaster and Sustainable Development -- Chapter 3. Understanding Disaster Risk Reduction and Resilience -- Chapter 4. Traditional management of Disaster: Indigenous Knowledge, Insights and Strategies -- Part II: Approaches to Disaster Management -- Chapter 5. Different types of Risks and Vulnerability -- Chapter 6. Fields of Response to Disaster: Positive Response and Negative Response -- Chapter 7. Disaster Resilience by Indigenous Communities -- Chapter 8. Capacity Building and Community Based Disaster Preparedness -- Part III: Sustainability Through Indigenous Knowledge and Practice -- Chapter 9. Disaster Risk Identification and Mitigation with the help of Traditional Knowledge -- Chapter 10. Disaster Risk Reduction through local Knowledge and practice-case studies -- Chapter 11. Adaptation to different types of Disaster with Integration of local Knowledge-case studies -- Chapter 12. Climate Risk Management with Indigenous Perception and Strategies- case studies -- Part IV: Science-Policy Interface Through Indigenous Knowledge -- Chapter 13. Integration of Indigenous Knowledge in Policy Formulation -- Chapter 14. Insights from Regional and Field Studies on Micro Policies -- Chapter 15. Perspectives from Indigenous Knowledge in Sustainable Development -- Chapter 16. Integration of Perception Studies and Disaster Risks -- Chapter 17. Development of a holistic Regional Disaster Policy Framework based on Indigenous Knowledge -- Chapter 18. Identifying the gaps and Future Scopes in Disaster Risk Reduction and Resilience -- Chapter 19. Conclusion.
    Abstract: The book seeks to comprehend how indigenous knowledge systems of local communities can be effectively used in disaster management of various types. A prime example is the 2015 Sendai Framework for Disaster Risk Reduction, promoting indigenous environmental management knowledge and practices. Traditional knowledge of indigenous peoples includes information and insight that supplement conventional science and environmental observations, a comprehensive understanding of the environment, natural resources, culture, and human interactions with them which is not documented before. A great deal of this knowledge have been lost in translation. In this book, the authors attempt to keep a record of each and every traditional knowledge study of the indigenous communities in managing the disasters. The use of indigenous knowledge systems in disaster understanding and management is the primary focus of the chapters. This book is organized into four major sections. The first part gives an overview and help in conceptualizing the different concepts of hazard and disaster perception and how response and adaptation are connected with it. This part also discusses the concept of the connection between hazard and sustainable development and how the understanding of risk reduction and resilience can happen with the help of indigenous knowledge, insights, and strategies. The second part of the book introduces the different approaches to disaster and risk management. It establishes how vulnerability influences the risk associated with a hazard and the responses can be both positive and negative in disaster management. The approaches of the indigenous communities in managing a disaster, their resilience, capacity building, and community-based preparedness will be the area of prime focus in this chapter. Part 3 of this book describes the concept of sustainability through indigenous knowledge and practice. The sole highlight of this chapter is the indigenous knowledge efficacies in disaster identification, risk reduction, climate risk management, and climate action. The last section of the book explores how to meet the gaps between local knowledge and policy formulation. It highlights how traditional knowledge of the indigenous communities can prove to be beneficial in developing a holistic regional-based policy framework which will be easily accepted by the target stakeholders since they will be more acquainted with the local strategies and methods. This section ends with an assessment and discussion of the gaps and future scopes in disaster risk reduction through integrating local knowledge and modern technologies.
    Type of Medium: Online Resource
    Pages: XXIX, 604 p. 200 illus., 187 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031261435
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geology. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Geophysics. ; Petrology. ; Geochemistry. ; Sedimentology. ; Geology. ; Fossil Fuel. ; Geophysics. ; Petrology. ; Geochemistry. ; Sedimentology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Regional geological characteristics of the Central Africa Rift System -- Chapter 3. Structural Characteristics of the Bongor Basin -- Chapter 4. Strata and Reservoir-cap Assemblages of Lower Cretaceous -- Chapter 5. Reservoir Characteristics of Basement -- Chapter 6. Source Rock and Hydrocarbon Geochemical Characteristics -- Chapter 7. Reservoir Geological Characteristics -- Chapter 8. Seismic Reservoir Prediction Techniques -- Chapter 9. Reservoir Comprehensive Logging Evaluation Techniques.
    Abstract: This book offers case study of the tridimensional exploration in whole exploration cycle with comprehensive and systematic geological and geophysical studies in the Bongor Basin. Focused on the typical intensively inversed rift basin—the Bongor Basin in Chad, this book establishes petroleum geology model, accumulation model of the typical intensively inversed rift basin and ensemble exploration techniques by studying comprehensively through the lens of structural geology, petrology, geochronology, sedimentology, paleontology, petroleum geochemistry, petroleum geology, and hydrocarbon accumulation dynamics studies on both granite buried hill and sandstone reservoir. Based on the cases in whole exploration cycle and abundant primary research resource (some are first published in public) in the Bongor Basin, this book is a valuable reference for researchers, managers, instructors, and students who engaged in petroleum exploration. .
    Type of Medium: Online Resource
    Pages: XVII, 486 p. 430 illus., 412 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811926730
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geochemistry. ; Sedimentology. ; Geology. ; Geochemistry. ; Sedimentology.
    Description / Table of Contents: Chapter1. Introduction of Field Geology -- Chapter2. Petrography -- Chapter3. Stratigraphy -- Chapter4. Geochemistry -- Chapter5. Sedimentalogy.
    Abstract: This book examines novel geological formations and lava flows of basaltic rock in India, and provides a comprehensive understanding of basaltic rock geology, petrography, stratigraphy and geochemistry. Readers are given insight into the geologic conditions of basaltic rock in central India, and a basic introduction to field geology methods and parameters in the study region. The author shows detailed petrographic and mineralogical characteristics of various basaltic rock formations, and identifies key features using major, trace and rare earth element stratigraphic analysis. An analysis of the sequence of hydro-geological formations of the basaltic rock area using ground water fluctuation models is also provided to assess surface and groundwater resources, which are important for planning development in the basaltic hard rock area. The book aims to be a resource for researchers, scientists, teachers and students interested in geology, petrography and geochemistry.
    Type of Medium: Online Resource
    Pages: XI, 256 p. 158 illus., 145 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031305740
    DDC: 551
    Language: English
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    Keywords: Geology. ; Sedimentology. ; Paleontology . ; Geodynamics. ; Geology. ; Sedimentology. ; Paleontology. ; Geodynamics.
    Description / Table of Contents: Chapter 1. Introduction and Back Ground History -- Chapter 2. The Ediacaran rock units -- Chapter 3. The Cambrian Period -- Chapter 4. The Ordovician Period -- Chapter 5. The Silurian Period -- Chapter 6. The Devonian Period -- Chapter 7. The Carboniferous Period -- Chapter 8. The Permian Period.
    Abstract: This book presents the following geological contributions in Ediacaran and Paleozoic rocks. 1) It introduces four new rock units for the first time, the Ediacaran El Urf Formation (volcanoclastic sediments in the central Eastern Desert), the Ediacaran Abu Haswa Formation (stromatolitic dolostone in southwestern Sinai), the Early Permian Wadi Dome Formation (mixed clastics and carbonates in the west of Suez Gulf) and the Early Permian Misawag Formation (in the subsurface, northwestern Desert), 2) making correlation of the Ediacaran rock units with the corresponding rock units in Libya, Jordan, Iraq and Saudi Arabia, 3) linking the exposed Paleozoic rock units with their equivalent rock units in subsurface in northwestern desert, 4) correlating the Paleozoic rock units with the equivalent rock units in adjacent countries, e. g. Libya, Jordan, Iraq and Saudi Arabia, 5) manifesting the possible depositional environments of the Ediacaran and Paleozoic rock units. Additionally, it offers an important unique geological information about the Ediacaran and Paleozoic rock units in Egypt. It unifies the nomenclature of Paleozoic rock units that take numerous names for the same geological time. It obsoletes the formation names that do not follow the rules of the North American stratigraphic code (1983) for rock units’ nomenclature. It provides the target audience illustrations, e.g. field photographs for the exposed rock units that save efforts and time for audience (undergraduate, post-graduate, researchers and professional) to reach to the original localities of each rock units. It provides the audience with schematic diagrams that exhibit the link between the exposed and subsurface rock units all over the Egyptian territory. It describes the following topics of each rock unit: definition, stratigraphic contact, lithological characteristics, faunal and floral associations that are used for the identification of the possible age, correlation with corresponding rock units in adjacent countries, e.g. Libya, Jordan, Iraq and Saudi Arabia and the possible depositional environments for each rock units. The book is a fundamental source of an updated version of the information in the field to the undergraduate, graduate, researchers, professional, practitioners and policy planning elsewhere.
    Type of Medium: Online Resource
    Pages: XVIII, 209 p. 113 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031273209
    Series Statement: Earth and Environmental Sciences Library,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Geotechnical engineering. ; Geographic information systems. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences. ; Geographical Information System.
    Description / Table of Contents: Part I: Terrestrial, Shipboard and Airborne Gravimetry -- Measurement of Absolute Gravity and Deflection of the Vertical at Sea -- Multi-scenario Evaluation of the Direct Method in Strapdown Airborne and Shipborne Gravimetry -- Improving Gravity Estimation Accuracy for the GT-2A Airborne Gravimeter Using Spline-Based Gravity Models -- Gravimetric Studies in the Sea of Japan -- About Identification of Instrument Error Parameters for a Gravity Gradiometer -- Numerical Model of Moving-Base Rotating Accelerometer Gravity Gradiometer -- New Algorithm for Gravity Vector Estimation from Airborne Data Using Spherical Scaling Functions -- Results of Astro-measurements of the Deflection of Vertical Using the New Observation Technique -- Observations with gPhone Gravimeter in Moscow -- Part II: Absolute Gravimetry -- On Uncertainties of Laser Interferometric Absolute Ballistic Gravimeters due to Magnetic Effects in the Free-Fall Gravity Measurements -- Evaluation of Systematic Errors in the Compact Absolute Gravimeter TAG-1 for Network Monitoring of Volcanic Activities -- Design of New Launch and Interferometer Systems for the IMGC-02 Absolute Gravimeter -- Twelve Years of High Frequency Absolute Gravity Measurements at the UK’s Space Geodesy Facility: Systematic Signals and Comparison with SLR Heights -- Part III: Relative Gravimetry and Applications -- Studying the Evolution of Resolution Capabilities and Approximation Accuracy of Global Models by Spectral Characteristics -- The Role of Non-tidal Atmospheric Loading in the Task of Gravity Field Estimation by Inter-satellite Measurements -- Formation of Self-consistent Navigational Gravity Maps of Local Areas and Joint Assessment of Their Navigation Quality -- Methods of Bistatic GNSS-radio Altimetry for Determining Height Profile of the Ocean and Their Experimental Verification -- Absolute and Relative Gravity Measurements at Volcanoes: Current State and New Developments Under the NEWTON-g Project -- The Effect of Measurement Preprocessing in the Gravity-Aided Navigation -- Sensitivity of Algorithms for Estimating the Gravity Disturbance Vector to Its Model Uncertainty.
    Abstract: This open access volume contains the proceedings of the 5th Symposium on Terrestrial Gravimetry: Static and Mobile Measurements (TG-SMM2019) held in St. Petersburg, Russia, October 1 – 4, 2019. The symposium was hosted by the State Research Center of the Russian Federation Concern CSRI Elektropribor, JSC and was attended by 75 participants from 15 different countries. 32 oral and 20 poster contributions were presented in four different topical sessions: Terrestrial, shipboard and airborne gravimetry, Absolute gravimetry, Relative gravimetry, gravity networks and applications of gravimetry and Cold atom and superconducting gravimeters, gravitational experiments.
    Type of Medium: Online Resource
    Pages: VIII, 160 p. 7 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031259029
    Series Statement: International Association of Geodesy Symposia, 153
    DDC: 551
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Spectrum analysis. ; Crystallography. ; Geology. ; Spectroscopy. ; Crystallography and Scattering Methods.
    Description / Table of Contents: 1. Introduction -- 2. Basic concepts -- 3. The petrographic microscope: a polarized light microscope -- 4. Optical properties of minerals in plane polarized light (PPL) -- 5. Optical properties of minerals in cross polarized light (XPL) -- 6. Conoscopic observations and interference figures -- 7. Igneous rocks: Some basic concepts -- 8. Metamorphic rocks: Some basic concepts -- 9. The mineral plates and how to use them -- Appendix.
    Abstract: This book presents a guide of optical mineralogy for beginners and microscopists who need to brush up their knowledge. It allows the fast identification of common rock-forming minerals in a thin section using a polarized light microscope and transmitted plane and cross polarized light. The book summarizes essential principles of optical mineralogy in numerous schemes. It explains, with the aid of more than 1000 microscopic images, how to determine the diagnostic optical characteristics of a mineral in a thin section. Seventy-two mineral plates of sixty-five common rock-forming minerals comprising typical microscopic images in plane and cross polarized light illustrate the most important optical and crystallographic parameters and their diagnostic characteristics and typical appearance in various geological settings. The original approach of the book is to facilitate mineral identification by mineral plates organized according to color in transmitted plane polarized light and, in each color category, according to decreasing maximum birefringence in cross polarized light. In addition, two chapters are devoted to the classification of magmatic and metamorphic rocks and their common mineral parageneses and textures. The book reflects the author’s experience of teaching optical mineralogy in the most efficient way possible to generations of students at the Universities of Heidelberg (Germany), Basel (Switzerland), and Geneva (Switzerland).
    Type of Medium: Online Resource
    Pages: XIII, 278 p. 281 illus., 253 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031196126
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Sedimentology. ; Geodynamics. ; Geology. ; Sedimentology. ; Geodynamics.
    Description / Table of Contents: The geological setting of the Moroccan High Atlas and its plate tectonics context -- Structure of the Central High Atlas (Morocco). Constraints from potential field data and 3D models -- Magnetic properties of the remagnetized carbonates of the Central High Atlas (Morocco) -- Paleomagnetism of the Central High Atlas. The widespread Cretaceous Remagnetization and structural implications -- Geodynamic evolution during the Mesozoic and Cenozoic in the Central High Atlas of Morocco from Anisotropy of Magnetic Susceptibility -- Kinematics of structures and basin evolution in the Central High Atlas. Constraints from AMS and paleomagnetic data.
    Abstract: This book presents a significant amount of structural, paleomagnetic and magnetic fabric data in the Central High Atlas (Morocco). The authors thoroughly described and analyzed the present-day structure of this intraplate chain through 22 of cross-sections, potential field data analysis and 3D reconstruction. In addition, the authors propose a palinspastic reconstruction of the structure of the basin at 100 Ma (i.e., post-extension and pre-compression) to finally evaluate its Mesozoic and Cenozoic geodynamic evolution. This books presents (1) a unique three-dimensional model at the chain scale, (2) an analysis of the ca. 100 Ma remagnetization, to perform palinspastic restorations of most representative structures, (3) as well as the interpretation of the magnetic fabrics in order to unravel the tectonic or deformation setting that the rocks underwent in different parts of the basin. This book is of interest to structural geologists in Northern Africa, the Mediterranean and Iberia, as well as to those interested in inverted intraplate basins and paleomagnetists from around the planet. Also, this book is intended to help students to understand better the geological evolution of the Atlas and therefore Morocco and surrounding areas.
    Type of Medium: Online Resource
    Pages: XXII, 646 p. 324 illus., 311 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031166938
    Series Statement: Springer Geology,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Sedimentology. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Geology. ; Sedimentology. ; Fossil Fuel.
    Description / Table of Contents: Introduction -- Geological Setting of the Ordovician and Silurian Strata of the Yangtze Platform -- Ordovician to Silurian Shale Gas-Bearing Strata from the Yangtze Region -- Distribution Pattern of the Ordovician–Silurian Shale Gas-Bearing Strata in the Yangtze Region -- Regional and Global Correlation of the Latest Ordovician to Early Silurian Shale Gas-Bearing Strata -- Paleogeography and Paleoenvironment Across the Ordovician– Silurian Transition in the Yangtze Region -- Gamma Log Responses Through the Ordovician–Silurian Black Shale Graptolite Zonal Succession in the Middle and Upper Yangtze Regions -- Volcanic Ash Deposition and Organic Matter Enrichment in the Black Shales of the Wufeng–Lungmachi Formations in the Yangtze Region -- Appendix Plates and Explanation. .
    Abstract: This book presents the accumulated data and current state of geological knowledge on China’s main shale gas fields. It addresses a broad range of topics, including the geological setting, reference sections and published boreholes, lithostratigraphy, biostratigraphy and chronostratigraphy, sedimentology and sequence stratigraphy of the late Ordovician to early Silurian, spatial and temporal distribution patterns and environmental changes in the black shales of the Wufeng and Lungmachi formations, numerical analysis of the Wufengian and Lungmachian Total Organic Carbon (TOC), late Ordovician to early Silurian bentonites of the Yangtze region, and a graptolite atlas of the Wufeng and Lungmachi formations. Given its scope, the book represents a valuable asset for researchers and petroleum engineers alike.
    Type of Medium: Online Resource
    Pages: IX, 237 p. 205 illus., 129 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819931347
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geology. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Geophysics. ; Geotechnical engineering. ; Geology. ; Fossil Fuel. ; Geophysics. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Introduction to Evaluation of Whole Petroleum System -- Unified Classification of Oil and Gas Reservoirs in WPS -- Buoyancy-driven Hydrocarbon Accumulation Depth in WPS.-Hydrocarbon Accumulation Depth Limit in WPS -- Active Source-rock Depth Limit in WPS -- Unified Model for Oil and Gas Reservoirs Formation -- Evaluation of Conventional Oil and Gas Reservoirs.-Prediction and Evaluation of Tight Oil and Gas Reservoirs.-Evaluation of Unconventional Shale Oil and Gas Resource.-Evaluation of Reformed and Destroyed Oil and Gas Reservoirs -- Evaluation of the Global Oil and Gas Resources -- Evaluation of the Global Potential Resource of the NGH.
    Abstract: This book introduces a complete quantitative evaluation system of the Whole Petroleum System (WPS) on theory and expounds the correlation and difference between conventional and unconventional oil and gas reservoirs and resources, with large number of well-prepared charts and novel expressions. It has important guiding significance for the exploration and development of conventional and unconventional oil and gas all over the world and provides valuable insights for reader with an interest in petroleum geology.
    Type of Medium: Online Resource
    Pages: XXXIV, 454 p. 224 illus., 216 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903252
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Mining engineering. ; Physical geography. ; Power resources. ; Environmental economics. ; Economic geography. ; Geology. ; Mining and Exploration. ; Physical Geography. ; Resource and Environmental Economics. ; Economic Geography.
    Description / Table of Contents: 1. Introduction: Early Years of Mining and Geology -- 2. Geological Survey for Jamaica -- 3. A Temporary Survey -- 4. The Bauxite Industry and its Development -- 5. The Modern Geological Survey -- 6. Transforming Jamaica’s Mining Sector.
    Abstract: Mining and geological survey work in Jamaica goes back several hundred years and was initiated by the Europeans when they colonized the Island. The year 2019 marked 160 years since the first Government-commissioned Geological Survey of Jamaica. This is one of the oldest survey activity of this type in the World! This book seeks to commemorate this heritage. It is one of the first books of its kind examining the evolution of the mineral sector and geological survey work of Jamaica, set in the framework of the Country's history of over 500 years. The Reader will explore a relatively unfamiliar side of the Country's development, linked to popular historical stories that shaped the Nation. The information presented are mostly documented in dated academic literature that are not gauged for a wide audience. This book however, aims to make this information accessible for a wider readership such as students, amateur scientist, non-professionals or anyone who wishes to learn about the rich history and heritage, and the contributions to national development from Europe and much later, North America.
    Type of Medium: Online Resource
    Pages: XVII, 158 p. 19 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031426049
    Series Statement: Historical Geography and Geosciences,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Environmental management. ; Climatology. ; Sustainability. ; Natural Hazards. ; Environmental Management. ; Climate Sciences. ; Sustainability.
    Description / Table of Contents: Literature on the visual hazard -- Land degradation and Desertification -- Process of Aeolian Action -- Surface micromorphology of Aeolian sand grains -- Source of sand for aeolian sand migration -- Impact of Desertification in semi-arid regions -- Long-term temporal analysis of desertification -- Controlling measures for a visual disaster. .
    Abstract: This book summarizes contemporary research on land degradation, desertification, and how such issues relate to socioeconomic growth in developing countries. With a focus on local and regional levels, the book offers an in-depth analysis of aeolian action as a physical process, causes of land degradation, and desertification. The causes and effects of land degradation were investigated by utilizing multiscale and multidisciplinary methodologies, merging spatial socioeconomic data with remote sensing data, and using multiple levels and disciplinary approaches. The book also describes how to combine GIS with cutting-edge technologies such as remote sensing, geostatistics, scanning electron microscopy (SEM) and energy-dispersive X-ray (EDAX) analysis, and analytical hierarchy approaches, among others. Included is a thorough case study of the unusual but understudied semi-arid Anantapur district in Andhra Pradesh, South India. This book encourages the participation of all socioeconomic groups in decision-making and assists authorities and planners in developing suitable plans for the sustainable agricultural growth of an area. The book is an invaluable resource to comprehend and resolve issues about sustainable environmental planning and management.
    Type of Medium: Online Resource
    Pages: XVII, 134 p. 48 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819967292
    Series Statement: Advances in Geographical and Environmental Sciences,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Natural disasters. ; Geotechnical engineering. ; Environmental monitoring. ; Natural Hazards. ; Geotechnical Engineering and Applied Earth Sciences. ; Environmental Monitoring.
    Description / Table of Contents: Chapter 1. Introduction to Hydrogeological Hazards -- Chapter 2. Loess Landslides and Water Resources Management -- Chapter 3. Land Subsidence and Groundwater Seepage -- Chapter 4. Earth Fissures and Natural Resources Mining -- Chapter 5. Karst Collapse and Its Management -- Chapter 6. Mine Water Inrush and Its Prediction -- Chapter 7. Groundwater Contamination and Induced Risk and Hazard in a Karst Aquifer.
    Abstract: This book addresses geohazards by establishing their unique hydrogeological conceptual site models. Geohazards occur in many forms and scales either naturally or induced by human's activities. Many geohazards such as earth fissure, ground collapse and subsidence, mine water inrush, and groundwater contamination are closely related to hydrogeological conditions and their dynamics. Water, either surface water or groundwater, acts as a resource and an enabling agent that elevates geohazard risks in areas that are inherently vulnerable. The book presents case studies to describe identification and investigation methods, monitoring and early-warning techniques, modeling approaches, and engineering measures to prevent, control, and mitigate these geohazards. It targets students, researchers, practitioners, and decision makers who are engaged in water resource management, project planning, and geohazard control and management.
    Type of Medium: Online Resource
    Pages: XIX, 261 p. 82 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031484278
    Series Statement: Environmental Earth Sciences,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Water. ; Hydrology. ; Physical geography. ; Emergency medical services. ; Natural Hazards. ; Environmental Social Sciences. ; Water. ; Earth System Sciences. ; Emergency Services.
    Description / Table of Contents: Chapter 1. Modeling Human Dimensions to Reduce the Disaster Risk: A Socio-Hydrological Approach -- Chapter 2. Improvement of Urban Socio-Hydrologic Resilience in Extreme Hydro-climatic Conditions -- Chapter 3. Fluvio-Geomorphic Hazard and Its Impact on Socio-Economy, A Study on Resilience and Sustainability in Assam -- Chapter 4. Effect of Climate Change on the Agricultural System of Hirakud Command Area -- Chapter 5. Mitigating the Negative Effects of Plastic Pollution For Sustainable Economic Growth In Nigeria -- Chapter 6. Teaching of Climate Change in the Official Documentation: An International Review For Improving the Resilience -- Chapter 7. Hydrologic Disasters: Assessing Hazard and Risks -- Chapter 8. Floods in Tutong District, Brunei Darussalam and the Role of Tutong River: Approaches for Mitigation Measures -- Chapter 9. Adaptation and Resilience Measures in The Face of Extreme Events in Algeria -- Chapter 10. Socio-Hydrological Role of North Africa's Traditional Water Management Systems Under.
    Abstract: This book is part of a six-volume series on Disaster Risk Reduction and Resilience. The series aims to fill in gaps in theory and practice in the Sendai Framework, and provides additional resources, methodologies and communication strategies to enhance the plan for action and targets proposed by the Sendai Framework. The series will appeal to a broad range of researchers, academics, students, policy makers and practitioners in engineering, environmental science and geography, geoscience, emergency management, finance, community adaptation, atmospheric science and information technology. This volume discusses the implementation of socio-hydrological resilience measures to curb the impacts on vulnerable communities of hydrologic diasters such as coastal floods, drought, water scarcity, and thunderstorms. The book provides a framework for sustainable hydrology-community interactions to inform local communities about the best practices to achieve hydrological resilience, and to implement resilient water infrastructure. Hydrological influences on the resilience of a region are comprehensively surveyed, and a "green economy strategy" is described and recommended for achieving climatic and hydrological sustainability. .
    Type of Medium: Online Resource
    Pages: XIV, 218 p. 61 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031431777
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Geomorphology. ; Geotechnical engineering. ; Natural Hazards. ; Geomorphology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Part I: ICL Landslide Lesson -- Sliding-surface liquefaction and undrained steady-state shear strength -- Identification and Mitigation of Reservoir Landslides Cases Studied in the Three Gorges Reservoir Area of China -- Part II: Original articles -- Impact of input data on the quality of the landslide susceptibility large-scale maps: A case study from NW Croatia -- Landslide warning systems in high-income countries: past accomplishments and expected endeavours -- Modelling of Landslide-Structure Interaction (LSI) through Material Point Method (MPM) -- Landslide Research and Technology in International Standards -- Mathematical and numerical modeling of slope stability for the Mong Sen landslide event in the Trung Chai commune, Sapa, Vietnam -- Landslide early warning system based on the empirical approach - Case study in Ha Long City (Vietnam) -- The modern activity of the Buzulgan landslide and its influence on the debris flow hazard for the Tyrnyauz town (Northern Caucasus, Russia) -- A risk evaluation method of unstable slopes using multipoint tilting sensors -- Part III: IPL/WCOE/KLC2020 -- Community Level Slope Disaster Risk Reduction Program through Multi-Scale Mapping by Mountain Ethnic Group in Northern Vietnam - Project Study by JICA / Lao Cai DARD / ITST -- Landslide Risk Assessment in the tropical zone of Vietnam as a contribution to the mitigation of natural disaster vulnerability -- Protection and conservation of Georgian rupestrian cultural heritage sites: a review -- Spatial and temporal characterization of landslide deformation pattern with Sentinel-1 -- Lessons from 2019-2020 landslide risk assessment in an urban area of volcanic soils in Pereira-Colombia -- Part IV: ICL Landslide Teaching Tools -- Zonation of landslide susceptibility in the Gipuzkoa province (Spain): an application of LAND-SUITE -- Landslide and soil erosion inventory mapping based on high-resolution remote sensing data: A case study from Istria (Croatia) -- Part V: Technical Notes and Case Studies -- Landslide monitoring with RADARSAT Constellation Mission InSAR, RPAS-derived point-clouds and RTK GNSS time-series in the Thompson River Valley, British Columbia, Canada -- Digital terrain models derived from unmanned aerial vehicles and landslide susceptibility -- Use of GIS to assess susceptibility per landform unit to gravitational processes and their volume.
    Abstract: This open access book provides an overview of the progress in landslide research and technology and is part of a book series of the International Consortium on Landslides (ICL). It gives an overview of recent progress in landslide research and technology for practical applications and the benefit for the society contributing to understanding and reducing landslide disaster risk. Prof. Irasema Alcántara-Ayala is a former Director and current Professor at the Institute of Geography of the National Autonomous University of Mexico (UNAM). She is a member of the UNDRR R-STAG of the Americas and an Editor of the ICL book series P-LRT. Prof. Željko Arbanas is the Vice President of the ICL for Europe. He is a professor at the Faculty of Engineering, University of Rijeka, Croatia. He is an Assistant Editor-in-Chief of the International Journal Landslides and the ICL book series P-LRT. Prof. Sabatino Cuomo Sabatino Cuomo is a Professor of Geotechnical Engineering at the University of Salerno and Coordinator of LARAM School (International School on “LAndslide Risk Assessment and Mitigation) for Ph.D. students. He is an Editor of the ICL book series P-LRT. Dr. David Huntley is Research Scientist with the Geological Survey of Canada and Open Learning Faculty at Thompson Rivers University, British Columbia. He is an Editor of the ICL book series P-LRT. Prof. Kazuo Konagai is a Professor Emeritus at the University of Tokyo and Principal Researcher of the ICL headquarters. He is an Assistant Editor-in-Chief of the ICL book series P-LRT. Prof. Snježana Mihalić Arbanas a Professor of the Faculty of Mining, Geology and Petroleum, University of Zagreb in Croatia. She is the Chair of ICL Network Committee. Matjaž Mikoš, Professor at the Faculty of Civil and Geodetic Engineering, University of Ljubljana, Slovenia, is the Chairman of the Global Promotion Committee of the International Programme on Landslides and Kyoto Landslide Commitment 2020. Prof. Kyoji Sassa is the Founding President and the Secretary General of the ICL and the Secretary General of the Kyoto Landslide Commitment 2020. He is the Editor-in-Chief of the International Journal Landslides and the ICL book series P-LRT. Dr. Shinji Sassa is the Head of Soil Dynamics Group and Research Director at Port and Airport Research Institute, National Institute of Maritime, Port and Aviation Technology, Japan. He is an Editor of the International Journal Landslides and the ICL book series P-LRT. Prof. Huiming Tang is the Vice President of China University of Geosciences (Wuhan) and a Chief Professor at the Faculty of Engineering. He is a full member of ICL, Chairman of the Engineering Geology commission of China and Vice President of IAEG. Prof. Binod Tiwari is the Vice President of the ICL for America. He is a professor of civil and environment engineering at the California State University, Fullerton California, USA. He is an Assistant Editor-in-Chief of the ICL book series P-LRT.
    Type of Medium: Online Resource
    Pages: XIII, 482 p. 408 illus., 395 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031390128
    Series Statement: Progress in Landslide Research and Technology,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geodynamics. ; Natural disasters. ; Geochemistry. ; Geology. ; Geodynamics. ; Natural Hazards. ; Geochemistry.
    Description / Table of Contents: El Hierro Island Volcanological Science: An Overview -- Past, Present and Future Volcanic Activity on El Hierro -- Review of Submarine Eruptions in El Hierro Prior to Tagoro -- From Magma Source to Volcanic Sink Under Tagoro Volcano (El Hierro, Canary Islands): Petrologic, Geochemical and Physiographic Evolution of the 2011-2012 Submarine Eruption -- Magma Storage and Migration in El Hierro During the Period 2011-2014 -- Geophysical, Geodetic and Geochemical Evidence for Precursory Activity: The 2011-2012 Tagoro Submarine Eruption -- Geomorphology of Tagoro Volcano Along Eruptive and Posteruptive Phases -- Ten Years of Intense Physical-chemical, Geological and Biological Monitoring Over the Tagoro Submarine Volcano Marine Ecosystem (Eruptive and Degassing Stages) -- Tagoro Submarine Volcano as a Natural Source of Significant Dissolved Inorganic Nutrients -- Microbial Communities Surrounding an Underwater Volcano near the Island of El Hierro (Canary Islands) -- Impact of Tagoro Volcano Formation on Benthic Habitats and Asscociated Biota: A Review -- Identification and Management of Indirect Volcanic Risks: Citizens’ Rockfall Observatory on the Island of El Hierro -- Tagoro, the Youngest Submarine Volcano in the Spanish Geoheritage Inventory: Scientific Value, Geoconservation and Opportunities for Geotourism.
    Abstract: This book presents an in-depth review of El Hierro Island, the youngest and most southwesterly volcano of the Canary Islands. In October 2011, a submarine eruption started offshore El Hierro Island. The 2011–2012 El Hierro eruption has probably been the best monitored and studied submarine eruption to date and has sparked interest in the study of this young ocean island volcano. During the last decade, multidisciplinary investigations, e.g., on the geological and volcanological character of its past and latest onshore and offshore eruptions, the geophysical and geochemical signatures of its magmatic plumbing system structure and dynamics, as well as the bio-geophysical interactions and consequences of submarine eruptions in the ocean, have been conducted. This book provides an authoritative review of many of these scientific advances as well as multiple remaining unknowns for the study of El Hierro Island and its 2011–2012 submarine eruption. Such knowledge should be of great interest to specialists not only in the Canary Islands volcanism but also in similar ocean island intraplate volcanoes.
    Type of Medium: Online Resource
    Pages: XI, 272 p. 82 illus., 81 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031351358
    Series Statement: Active Volcanoes of the World,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Environmental management. ; Water. ; Hydrology. ; Geomorphology. ; Natural Hazards. ; Environmental Management. ; Water. ; Geomorphology.
    Description / Table of Contents: 1-Ganga-Brahmaputra-Megna Delta in context -- 2-Emerging floods in the wake of the delta subsidence and sea level rise -- 3-Sediment Regime, Hydro-climatology of the Floods and Sea-level Movements in the Bengal Basin -- 4-Human activities and flood propensity -- 5-Predicting river flood hazard with sparse data: prospects and challenges for the Global South -- 6-Flood and Floodplain Management in the Bengal Basin: The Context of Sustainable Livelihood in the Flood Affected Areas -- 7-Flash flood in Indian part of GBM delta -- 8-Flash flood of Bangladesh part of GBM Delta -- 9-Floods of Teesta River -- 10-Floods of Torsa River -- 11-Floods of Jaldhaka River -- 12-Lis-Murti-Chel Rivers -- 13-Floods of Dharla and Dudhkumor Rivers -- 14-Floods of Mahananda-Balason Rivers -- 15-Floods of Atrai River -- 16-Floods of Purnabhaba River -- 17-Floods of Ganga River -- 18-Floods of the Padma River -- 19-Floods of Brahmaputra River -- 20-Floods of Old Brahmaputra River -- 21-Floods of Bhagirathi River -- 22-Floods of Jamuna River -- 23-Floods of Buriganga and Sitalakha Rivers -- 24-Floods of Surma and Kusiara Rivers -- 25-Floods of Mayurakshi River -- 26-Floods of Ajay River -- 27-Floods of Jalangi and Churni-Mathabhanga River -- 28-Floods of Damodar River system -- 29-Floods of Khari-Behula-Ghea Rivers -- 30-Floods of Dwarakeswar River -- 31-Floods of Shilabati River -- 32-Floods of Kansabati River -- 33-Floods of Keleghai and Rasulpur Rivers -- 34-Floods of Subarnarekha River -- 35-Floods of Ichhamati River -- 36-Floods of Hugli River -- 37-Floods of Meghna River -- 38-Floods of Garai-Madhumati and Arial Khan Rivers -- 39-Floods of Digha-Kanthi Coastal plains -- 40-Floods of Indian Sundarbans (north) -- 41-Floods of Indian Sundarbans (south) -- 42-Floods in Bangladesh Sundarbans -- 43-Tide and Storm Surge induced Floods in the Coastal Belt of Bangladesh.
    Abstract: This volume covers the floods of the major rivers of the Ganga-Brahmaputra-Meghna (GBM) Delta, and storm surge related coastal floods in these regions. The book is dedicated to addressing floods from an integrated physical-social perspective to provide students and researchers with a holistic understanding of floods in terms of both human and geomorphological aspects. The systematic coverage of all the major rivers and coastal areas in the GBM delta and surrounding regions will foster a clear comprehension of this dense reservoir of population, where thousands of people are impacted every year due to flood hazards and agricultural destabilization. This comprehensive treatment of flood issues in the region covers flash floods, fluvial floods, fluvio-tidal floods, and coastal floods, and outlines flood management strategies to maintain ecological integrity and environmental stability, and prevent harmful impacts of future floods. The book is intended for students and researchers in earth and environmental sciences, especially geomorphology, hydrology, geography, geology, natural resources management, and regional planning.
    Type of Medium: Online Resource
    Pages: XXIII, 557 p. 213 illus., 199 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031210860
    Series Statement: Springer Geography,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Natural disasters. ; Atmospheric science. ; Environment. ; Natural Hazards. ; Atmospheric Science. ; Environmental Sciences.
    Description / Table of Contents: Foreword -- Preface -- List of Abbreviations and Definitions -- Acknowledgements -- 1 Introduction -- 2 Arizona is the lightning photography capital of the U.S. -- 3 When, where, and how much lightning occurs in Arizona -- 4 Human impacts, damages, and benefits from lightning in Arizona -- 5 How lightning detection netweorks were developed -- Studies of lightning in Arizona -- Index. .
    Abstract: This book is a comprehensive resource on lightning and describes the unique roles which the state of Arizona has with regard to lightning. Not only is it spectacular, it is also admired, feared, and misunderstood, but its knowledge has come of age in the last two decades. This book describes why Arizona can be called the “Lightning Photography Capital of the U.S.”, how the general public and Native Americans in Arizona have viewed lightning, and when and where lightning occurs and impacts people and resources in Arizona. It contains summaries of interviews with current and former University of Arizona staff who invented real-time lightning detection in the late 1970s and how subsequent lightning research in Arizona has been globally significant. The authors are very well acquainted with and up to date on these topics. The style of this book is active and somewhat scholarly but readable by the nonprofessional with a general interest in lightning. What is lightning? How does lightning affect Arizona? Why do photographers come to Arizona for lightning photographs? What is unique about Arizona lightning? How is lightning detected in Arizona and around the world? This book tells you answers to these questions. This book is intended for a broad audience comprised of visitors, interested lay public, a variety of scientific disciplines, media, medicine, lightning safety, and fire weather. It is suitable for readers desiring a general overview of lightning, especially in Arizona, but also for those who want to know specifically about the topic.
    Type of Medium: Online Resource
    Pages: XVIII, 231 p. 86 illus., 78 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031198793
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Tourism. ; Management. ; Geomorphology. ; Environmental geography. ; Geography. ; Geology. ; Tourism Management. ; Geomorphology. ; Integrated Geography. ; Regional Geography.
    Description / Table of Contents: Part I. Introduction and setting the scene. Chapter 1. Geotourism – A Global Overview -- Chapter 2. The Geotourism Potential of Sand and Dunes – From Theory To Practice -- Chapter 3. The Significance of Geotourism Through the Lens Of Geoethics -- Chapter 4. Geotourism in The Middle East- An Overview -- Part II. Country case studies -- Chapter 5. Geotourism in Egypt -- Chapter 6. Geotourism in Iran, A Review -- Chapter 7. Residents’ Perceptions of Geotourism in Qeshm Island UNESCO Global Geopark, Iran -- Chapter 8. Geotourism in Iraq – With Reference to Potential Geoheritage and Geoparks -- Chapter 9. Geotourism in Jordan: The Potential for Developing Geotrails in The Wadis -- Chapter 10. Geotourism In The Sultanate Of Oman – With a Focus on Samail Ophiolite Geosites -- Chapter 11. Geotourism in Qatar -- Chapter 12. Geotourism in Yemen -- Chapter 13. Geotourism in Saudi Arabia -- Chapter 14. Geotourism in Türkiye – Cave Assessment Using Geographical Information Systems -- Chapter 15. Geotourism in Palestine -- Chapter 16. Geotourism in the United Arab Emirates -- Part III. Conclusion. Chapter 17. Conclusion - The Future of Geotourism in The Middle East.
    Abstract: The geotourism industry has grown rapidly in recent years. This book introduces the geotourism industry, its attractions, activities and developments, in selected countries of the Middle East. A number of publications and studies have investigated the nature and scope of the phenomenon of geotourism (tourism which starts from geology) and geotourists worldwide. However, despite the breadth of these studies, few publications have investigated the phenomena in the Middle Eastern countries. Consequently, this book seeks to shed light on the different aspects of geotourism and geo-diversity in the Middle East and provides a number of case studies from this region. It assists in bridging the lacuna in the tourism and geology literature and helps planners, marketers, managers, scholars and researchers to enhance their knowledge about such issues. It outlines opportunities for, as well as barriers to, geotourism development in the Middle East as well as providing recommendations for the advancement of geotourism in the region.
    Type of Medium: Online Resource
    Pages: XV, 278 p. 240 illus., 232 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031241703
    Series Statement: Geoheritage, Geoparks and Geotourism, Conservation and Management Series,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Natural disasters. ; Water. ; Hydrology. ; Physical geography. ; Geomorphology. ; Geology. ; Geotechnical engineering. ; Natural Hazards. ; Water. ; Physical Geography. ; Geomorphology. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Introduction -- Hydrologic analysis of Tangjiashan barrier lake area -- Geological characteristics of Tangjiashan barrier lake area -- Outburst flood evolution analysis of Tangjiashan barrier lake -- Study on the anti-impact stability of discontinuous wide graded mixture of weir body -- Study on the emergency danger elimination plan of Tangjiashan barrier lake -- Construction of Tangjiashan barrier lake emergency danger elimination project -- Emergency monitoring and assurance system -- Evaluation of the discharge process of lake water and the effect of risk removal.
    Abstract: This book introduces emergency management of barrier lakes systematically, including theories and practices, risk assessment under extremely high-risk conditions, evolution of outburst floods, analysis of anti-impact stability, and emergency management technology and assessment of risk elimination effect. It takes the Tangjiashan barrier lake as a successful case study to illustrate effective treatment of barrier lake with high risks, poor environmental conditions, extremely urgent rescue time and high disposal difficulties. It retains a large number of images and data of great research value for the lake risk assessment and building technological emergency system. It provides a reliable reference for the government, scientific researchers and survey and design team to deal with the sudden natural disaster in barrier lakes, especially caused by huge earthquake.
    Type of Medium: Online Resource
    Pages: XVII, 342 p. 164 illus., 115 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819917068
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Geology. ; Water. ; Hydrology. ; Sedimentology. ; Geotechnical engineering. ; Geology. ; Water. ; Sedimentology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: INTRODUCTION -- NATURAL CHARACTERISTICS -- CATCHMENTS, SURFACE FLOWS -- UNDERGROUND MORPHOLOGY AND FAUNA -- WATER RESOURCES PROJECTS -- INFLUENCE AND CONSEQUENCES OF WATER RESOURCES PROJECTS -- CHEMISTRY AND WATER QUALITY.
    Abstract: The area of Eastern Herzegovina is one of the most karstified regions in the world. Deep karst, sinking rivers, underground flows, temporary flooded karst poljes and lack of arable land is main natural property of the region. Due to two kinds of misfortune, flood and drought, people have emigrated from this region searching for a better life. The book contains new scientific data and engineering experience collected during more than 100 years of investigations and construction. To provide optimum water management and economic development, thousands of new data are collected and presented in the book. Necessity for balance between regional development and preservation of nature was one of the important request.
    Type of Medium: Online Resource
    Pages: XIV, 316 p. 339 illus., 173 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031281204
    Series Statement: Cave and Karst Systems of the World,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Geomorphology. ; Geotechnical engineering. ; Natural Hazards. ; Geomorphology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Chapter 1. Editorial of the new open access book series “Progress in Landslide Research and Technology” (Kyoji Sassa) -- Part I. Original Articles -- Chapter 2. Key Techniques of Prevention and Control for Reservoir Landslide Based on Evolutionary Process (Huiming Tang) -- Chapter 3. Landslide research and technology in patent documents (Matjaž Mikoš) -- Chapter 4. Scalable Platform for UAV Flight Operations, Data Capture, Cloud Processing and Image Rendering of Landslide Hazards and Surface Change Detection for Disaster-Risk Reduction (David Huntley) -- Chapter 5. Ongoing persistent slope failures at the toe of a giant submarine slide in the Ryukyu Trench that generated the AD 1771 Meiwa tsunami (Kiichiro Kawamura) -- Chapter 6. Experimental simulation of landslide creep in ring shear machine (Netra Prakash Bhandary) -- Chapter 7. Assessment of the effects of rainfall frequency on landslide susceptibility mapping using AHP method: a case study for a mountainous region in central Vietnam (Chi Cong Nguyen) -- Chapter 8. Suffosion landslides as a specific type of slope deformations in the European part of Russia (Oleg V. Zerkal) -- Chapter 9. In situ triaxial creep test on gravelly slip zone soil of a giant landslide: innovative attempts and findings (Qinwen Tan) -- Chapter 10. Challenges and lessons learned from heavy rainfall induced geo-disasters over the last decade in Kyushu Island, Japan (Noriyuki Yasufuku).
    Abstract: This open access book provides an overview of the progress in landslide research and technology and is part of a book series of the International Consortium on Landslides (ICL). It gives an overview of recent progress in landslide research and technology for practical applications and the benefit for the society contributing to understanding and reducing landslide disaster risk. Prof. Irasema Alcántara-Ayala is a former Director and current Professor at the Institute of Geography of the National Autonomous University of Mexico (UNAM). She is a member of the UNDRR R-STAG of the Americas and an Editor of the ICL book series P-LRT. Prof. Željko Arbanas is the Vice President of the ICL for Europe. He is a professor at the Faculty of Engineering, University of Rijeka, Croatia. He is an Assistant Editor-in-Chief of the International Journal Landslides and the ICL book series P-LRT. Dr. David Huntley is Research Scientist with the Geological Sur vey of Canada and Open Learning Faculty at Thompson Rivers University, British Columbia. He is an Editor of the ICL book series P-LRT. Prof. Kazuo Konagai is a Professor Emeritus at the University of Tokyo and Principal Researcher of the ICL headquarters. He is an Assistant Editor-in-Chief of the ICL book series P-LRT. Matjaž Mikoš, Professor at the Faculty of Civil and Geodetic Engineering, University of Ljubljana, Slovenia, is the Chairman of the Global Promotion Committee of the International Programme on Landslides and Kyoto Landslide Commitment 2020. Prof. Kyoji Sassa is the Founding President and the Secretary General of the ICL and the Secretary General of the Kyoto Landslide Commitment 2020. He is the Editor-in-Chief of the International Journal Landslides and the ICL book series P-LRT. Dr. Shinji Sassa is the Head of Soil Dynamics Group and Research Director at Port and Airport Research Institute, National Institute of Maritime, Port and Aviation Technology, Japan. He is an Editor of the International Journal Landslides and the ICL book series P-LRT. Prof. Huiming Tang is the Vice President of China University of Geosciences (Wuhan) and a Chief Professor at the Faculty of Engineering. He is a full member of ICL, Chairman of the Engineering Geology commission of China and Vice President of IAEG. Prof. Binod Tiwari is the Vice President of the ICL for America. He is a professor of civil and environment engineering at the California State University, Fullerton California, USA. He is an Assistant Editor-in-Chief of the ICL book series P-LRT.
    Type of Medium: Online Resource
    Pages: XVI, 475 p. 435 illus., 416 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031184710
    Series Statement: Progress in Landslide Research and Technology,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geology. ; Geodynamics. ; Mineralogy. ; Natural disasters. ; Geology. ; Geodynamics. ; Mineralogy. ; Natural Hazards.
    Description / Table of Contents: Project Overview -- Research Status and Development Trend -- Major Research Achievements -- Outlook.
    Abstract: This book mainly introduces overview of “Destruction of the North China Craton”, a major research plan of NSFC. It summarizes the scientific ideas, core key scientific issues, scientific research objectives, and models of the major research plan of "Destruction of the North China Craton". From the perspective of major national needs and scientific discipline development, the book focuses on the following aspects: the temporal and spatial distribution range, process, and mechanism of the NCC destruction; the properties, structure, and interaction of materials in different spheres in the earth during craton destruction; the shallow effect of craton destruction; and the control mechanism of mineral resources, energy, and disasters. The book also makes a strategic prospect for the study of global dynamics and improves human understanding of the formation and evolution of continents.
    Type of Medium: Online Resource
    Pages: XV, 73 p. 30 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819960460
    Series Statement: Reports of China’s Basic Research,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Geophysics. ; Geology. ; Artificial intelligence. ; Natural Hazards. ; Geophysics. ; Geology. ; Artificial Intelligence.
    Description / Table of Contents: Role of active tectonics in the estimation of seismic hazard of an area: A case study of western India -- Stress Scenario In The North-West Himalaya: What We Learnt From Post-Seismic Stress Changes -- The crust and upper mantle structure beneath the Bangladesh and its effects on seismic hazard -- Seismological data quality controls – a synthesis -- Use of Geophysical techniques in Seismic Hazard Assessment and Microzonation -- Earthquake response and its implications towards the structural design codes for Himalayan and adjoining regions of India -- Liquefaction Potential Index (LPI): A Parameter to Assess Liquefaction Hazard -- Earthquake Precursory Studies Using Radon Time Series Data in Taiwan: An Overview -- Spatial prediction of earthquake-induced landslide susceptible zones - A case study from Indian Himalaya -- Tsunamis in the past and recent years over Indian coasts: A review -- Instrumentation of India’s First Regional Earthquake Early Warning System and Site Characterization of its Stations -- Overview of Artificial Intelligence (AI) and Machine Learning (ML) in Seismology. .
    Abstract: This book presents a comprehensive analysis of diverse aspects of geohazards. The growing vulnerability and exposure to failures in risk reduction and policy-making increases the severity of geohazard impacts by many folds. Therefore, detailed geohazard analysis, modelling and forecasting are needed to reduce the impacts of extreme events. An interdisciplinary approach to hazard mitigation provides an advanced tool for risk reduction. The book thus summarizes recent modelling and analysis techniques for hazard assessment and risk mitigation. Topics discussed in the book are hazard and risk associated with earthquakes, vulnerability assessment for landslides and avalanches, the assessment of tsunami risk in coastal regions, the implementation of early warning systems to prevent catastrophic consequences, climate change risk modelling and risk communication. The convergent approach with the aspects of natural, engineering, and social sciences attracts a vast audience working to advance disaster science. This book also significantly facilitates the acquisition of policy-relevant knowledge for risk reduction, which is beneficial to the general public.
    Type of Medium: Online Resource
    Pages: XIV, 193 p. 67 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819939558
    Series Statement: Advances in Natural and Technological Hazards Research, 53
    DDC: 551
    Language: English
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    Keywords: Neurosciences. ; Biomedical engineering. ; Nanotechnology. ; Biophysics. ; Imaging systems in biology. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Nanoengineering. ; Bioanalysis and Bioimaging. ; Biological Imaging.
    Description / Table of Contents: Part 1 -- Optically-Pumped Magnetometers Compatible with Large Transient Magnetic Fields -- Small animal biomagnetism applications -- Supine OPM-MEG in Multi-layer Cylindrical Shield -- Ambulatory MEG Arrays -- Part 2 -- "Tri-axial helium-4 optically-pumped -- magnetometers for MEG" -- Person-Sized Magnetoencephalography Systems with Optically Pumped Magnetometers -- On-scalp MEG with High-Tc SQUIDs -- "Fiber Coupled OPM in Purely Coil -- Shielded Environment" -- SERF-OPM usability for MEG in two-layer shielded rooms -- Turning OPM-MEG into a Wearable Technology -- Part 3 -- OPM Gradiometer for Magnetorelaxometry -- Unshielded High Bandwidth Magnetorelaxometry of Magnetic Nanoparticles with Optically Pumped Magnetometers -- Adult Magnetocardiography: Principles and Clinical Practice -- Fetal Magnetocardiography with OPMs -- Emerging MR sensors for biomagnetic measurements -- Index.
    Abstract: This contributed volume reviews the latest advances in all the new technologies currently developed for MagnetoEncephaloGraphy (MEG) recordings, as well as sensor technologies and integrated sensor arrays for on-scalp MEG. The book gives an account of the first MEG imaging studies and explores the new field of feasible, experimental paradigms of on-scalp MEG. This is an ideal book for engineers, researchers, and students in the neurosciences interested in MEG imaging. .
    Type of Medium: Online Resource
    Pages: IX, 315 p. 104 illus., 88 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031053634
    DDC: 612.8
    Language: English
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    Keywords: Neurosciences. ; Animal culture. ; Veterinary medicine. ; Neuroscience. ; Animal Science. ; Veterinary Science.
    Description / Table of Contents: Rodents -- Carnivores -- Sheep and goats -- Swine -- Rabbits -- Bovines -- Non-human primates -- Humans -- Squirrels.
    Abstract: Modern neuroscience has presented new opportunities for exploring the molecular and neural mechanisms controlling specific social responses. This book reviews insights into the neural circuits underlying a particularly fascinating form of social interaction, parental behavior. This book presents a detailed review of maternal and paternal behavior of particular mammalian species. It offer neuroscientists a spectrum of specific mammals that can be used as experimental models to explore particular topics on the functions of the nervous system. It shows that results coming from the laboratory can be translated into useful information for raising mammals on the farm, and it stimulates biologists to gain insights into the underpinnings of the complex mechanisms governing mammalian behavior in the wild. It also discusses the implications of this research for human parental behavior. .
    Type of Medium: Online Resource
    Pages: V, 309 p. 45 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030977627
    Series Statement: Advances in Neurobiology, 27
    DDC: 612.8
    Language: English
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  • 85
    Keywords: Neurosciences. ; Life sciences. ; Biology Technique. ; Evolution (Biology). ; Neuroscience. ; Life Sciences. ; Experimental Organisms. ; Evolutionary Biology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2.General Rules of Brain Morphogenesis in Vertebrates: An Hourglass Model -- Chapter 3.Neural Tube Formation -- Chapter 4.Subdivisions of Neural tube along the Dorsoventral Axis -- Chapter 5. Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models -- Chapter 6.Left-right Patterning of Neural Tube -- Chapter 7. Ventriculo-pial Patterning of Neural Tube -- Chapter 8.Development of Neural Circuits in Neural Tube -- Chapter 9.From Neural Tube to Larval Brain: Blood Vessels and Proliferative Zones -- Chapter 10. Development of Telencephalon -- Chapter 11. Development of Diencephalon, Optic Tectum, and Cerebellum -- Chapter 12. Nervous System in Medaka Larvae -- Chapter 13.From Larval Brain to Adult Brain and Summary of Telencephalic Ontogenesis -- Chapter 14. Adult Brain and General Brain Functions -- Chapter 15. Functional Neuroanatomy of Teleost Brains.
    Abstract: This book describes the developmental process of the brain of the medaka fish. It aims to understand the brain structure of vertebrates, including humans, by taking the brain of the medaka fish as an example and showing its actual developmental process. From developmental and evolutionary viewpoints, the understanding of the brain proceeds from simple to complex structures. Fish retain the basic form of vertebrates, and their brain morphology is relatively simple. Therefore, the fish brain is useful in understanding the brain structure. This book is unique for describing the entire process of the brain development in a specific fish. In addition, the book introduces the readers to a new concept of “Hourglass of Brain Morphogenesis”, concerning the general rule of brain morphogenesis in vertebrates. The authors propose that the brain morphology is highly conserved at the middle developmental stage but diverges more extensively at earlier and later stages. The new concept challenges the accepted theory that has been widely shared for about 200 years since K. von Baer (1828, 1837) and K. von Kupffer (1906) who proposed that three primary brain vesicles at earlier developmental stages develop into five secondary brain vesicles at later developmental stages in all vertebrates. The book provides a basic understanding of the vertebrate brain and is useful for all readers who wish to understand the complex structure of the brain. .
    Type of Medium: Online Resource
    Pages: XIV, 256 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811943249
    DDC: 612.8
    Language: English
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  • 86
    Keywords: Neurosciences. ; Zoology. ; Medical genetics. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Zoology. ; Medical Genetics. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. ApoE: A Risk Factor for Dementia -- Chapter 2. Infection-Induced Systemic Inflammation and Dementia -- Chapter 3. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia -- Chapter 4. Sex Hormones as Risk Factors of Dementia -- Chapter 5. Mitophagy Impairments as Culprit of Alzheimer’s Disease -- Chapter 6. Parkinson’s Disease: Neurochemistry and Pharmacological Treatment -- Chapter 7. Emerging Roles of TREM2 in Neurodegenerative Diseases -- Chapter 8. Molecular Mechanisms Underlying the Role of HSPB8 in Neurodegeneration -- Chapter 9. Molecular Insights into the Role of ER Stress in Neurodegenerative Diseases. Chapter 10. Role of Hypertension and Hyperlipidemia in the Pathogenesis of Dementia -- Chapter 11. Behavioral Abnormalities of Gut Microbiota and Progression of Dementia -- Chapter 12. Gut-Brain Axis in Alzheimer's Disease: Interplay between Cholecystokinin, Dysbiosis, and Brain-Derived Neurotrophic Factor -- Chapter 13. Cholesterol and Dementia: A Possible Therapeutic Approach -- Chapter 14. Therapeutic Potential of PPARs in Alzheimer’s Disease -- Chapter 15. Exploring the Role of Statins in Reversing the Cognitive and Neurovascular Dysfunctions in Dementia -- Chapter 16. Role of Immunotherapy in Ameliorating Proteopathic Dementia -- Chapter 17. Hypoxic-Hyperoxic Training in Dementia -- Chapter 18. Music Therapy in Dementia -- Chapter 19. Beneficial Effects of Citrus Flavonoids against Aβ Pathology in Alzheimer’s Disease -- Chapter 20. Therapeutic Potential of Phytochemicals: Lessons Learned from Streptozotocin-Induced Sporadic Alzheimer’s Disease -- Chapter 21. Concept of Amnesia and Dementia in Unani System of Medicine -- Chapter 22. Nanotechnological Applications in the Diagnosis and Treatment of Alzheimer’s Dementia.
    Abstract: This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
    Type of Medium: Online Resource
    Pages: XV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811676062
    DDC: 612.8
    Language: English
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  • 87
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Stem cells. ; Nervous system Regeneration. ; Neuroscience. ; Stem Cell Biology. ; Regeneration and Repair in the Nervous System.
    Description / Table of Contents: 1 Regenerative Therapies in Ischemic Stroke Recovery -- 2 Application of Nanotechnology In Stroke Recovery -- 3 Nanotechnology: A daydream for advanced Imaging, Diagnosis and Therapeutic Approach for Cerebral Ischemia -- 4 Cell-Mediated Neurorestorative Mechanisms Underpinning Beneficial Effects in Ischemic Stroke -- 5 Induced Pluripotent Stem Cells for the Treatment of Neurodegenerative Disease: Current and Future Prospects -- 6 Imaging of Stem Cell Therapy for Stroke and Beyond -- 7 Nano-Medicine Mediated Stem Cell Therapeutics In Stroke -- 8 The Influence of Preconditioning on the Homing Behaviour of Stem Cells -- 9 Role of microRNAs in stroke pathology and recovery -- 10 Exosomes as a diagnostic tool and stem cells exosomes as a promising cell-based cell-free therapeutic tool for ischemic stroke 11 Role of nanomedicine in treating ischemic stroke -- 12 Insights into therapeutic targets in stroke -- 13 Signalling Pathways of Interest for Recovery from Ischemic Stroke.
    Abstract: This book illustrates the importance and significance of regenerative medicine in stroke recovery. It discusses stem-cell-based treatment strategies and offers mechanistic insights into their role in neurological recovery. It also examines the challenges and advances in using adult stem cells for enhanced therapeutic efficacy. Further, it presents the strategies as well as the strengths and weaknesses of various delivery methods to administer stem cells in ischemic stroke. It examines the role of non-coding RNA in our understanding the stroke pathogenesis, their regulatory role in ischemic stroke and potential as biomarkers and therapeutic targets. Lastly, it explores exosomes in the treatment of stroke, and the underlying mechanism of their action as therapeutic vectors for stroke. Given its scope, it is an excellent resource for neurologists, neuroscientists and researchers involved in regenerative therapy for stroke.
    Type of Medium: Online Resource
    Pages: XIII, 353 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811685620
    DDC: 612.8
    Language: English
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  • 88
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Cognitive neuroscience. ; Social evolution. ; Neuroscience. ; Cognitive Neuroscience. ; Social Evolution.
    Description / Table of Contents: Part I Differentiation-Integration Dynamics: Ultimate Causes -- Chapter 1: Introduction -- Chapter 2: Purposeless Design -- Chapter 3: Darwinian Evolutionary Theory -- Chapter 4: Principles of Differentiation and Integration -- Chapter 5: The Information Trend in Science -- Chapter 6: Is Social Cohesion a Different Mechanism of Evolution? -- Part II Roots and Mechanisms: Proximate Causes -- Chapter 7: Fundamental Physical Forces, Genes, and Epigenetics -- Chapter 8: Biological Origins -- Chapter 9: Neural Mechanisms of Sociality -- Chapter 10: Psychological Features -- Chapter 11: Cognitive Science Underpinnings -- Chapter 12: A Sociological Systems Theory -- Chapter 13: Developmental Roots -- Chapter 14: Metaphysical, Religious, and Spiritual Aspects -- Part III Survival Value -- Chapter 15: Sociality’s Survival Value -- Part IV Conclusions -- Chapter 16: A New Framework: A Theory of Integration.
    Abstract: This book is an exploration of the integration-differentiation dynamics that result in a drive, or impulse, toward human sociality, arguing that our need to connect with other people is as fundamental as our need for food and shelter. In The Social Impulse: The Evolution and Neuroscience of What Brings Us Together, Jaime Pineda presents the evidence that social cohesion is a complementary force to natural selection, the Darwinian drive for differentiation and diversity. The book addresses the distinctive aspects of social behavior that arise from integration principles and seeks to answer the following questions: (1) Why does social cohesion arise? (2) What is the history of social dynamics? (3) How does social cohesion work? (4) When do the developmental aspects of social dynamics arise? A final section of the book addresses the value of sociality and social cohesion. By exploring the differences, similarities, and, most important, the interactivity between natural selection and social cohesion, this unique book provides a wealth of interesting, challenging, and unexpected insights.
    Type of Medium: Online Resource
    Pages: XXV, 190 p. 7 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031084393
    DDC: 612.8
    Language: English
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  • 89
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Pain medicine. ; Clinical psychology. ; Neuroscience. ; Pain Medicine. ; Clinical Psychology.
    Description / Table of Contents: Chapter 1. Conceptualising Pain in Critically-Ill Neonates or Infants -- Chapter 2. Pain in the Fetus and the Preterm Baby -- Chapter 3. Developmental Influences on the Meanings of Pain in Children -- Chapter 4. “Ooh, You Got to Holler Sometime:” Pain Meaning and Experiences of Black Older Adults -- Chapter 5. Exploring the Meaning of Chronic Low Back Pain as a Life of ‘Living Death’ in Rural Nigeria -- Chapter 6. Painworld: A Phenomenological View of Veteran Experiences of Living with Chronic Pain -- Chapter 7. “It’s Just One of Them Things You’ve Got to Try and Manage”: Meanings of Pain for People with Brain Injury.
    Abstract: This book, the third and final volume in the Meaning of Pain series, describes what pain means to people with pain in “vulnerable” groups, and how meaning changes pain – and them – over time. Immediate pain warns of harm or injury to the person with pain. If pain persists over time, more complex meanings can become interwoven with this primitive meaning of threat. These cognitive meanings include thoughts and anxiety about the adverse consequences of pain. Such meanings can nourish existential sufferings, which are more about the person than the pain, such as loss, loneliness, or despair. Although chronic pain can affect anyone, there are some groups of people for whom particular clinical support and understanding is urgently needed. This applies to “vulnerable” or “special” groups of people, and to the question of what pain means to them. These groups include children, women, older adults, veterans, addicts, people with mental health problems, homeless people, or people in rural or indigenous communities. Several chapters in the book focus on the lived experience of pain in vulnerable adults, including black older adults in the US, rural Nigerians, US veterans, and adults with acquired brain injury. The question of what pain experience could mean in the defenceless fetus, neonate, pre-term baby, and child, is examined in depth across three contributions. This book series aspires to create a vocabulary on the “meanings of pain” and a clinical framework with which to use it. It is hoped that the series stimulates self-reflection about the role of meaning in optimal pain management. Meanings of Pain is intended for people with pain, family members or caregivers of people with pain, clinicians, researchers, advocates, and policy makers. Volume I was published in 2016; Volume II in 2019.
    Type of Medium: Online Resource
    Pages: VII, 147 p. 5 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030958251
    DDC: 612.8
    Language: English
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  • 90
    Keywords: Neurosciences. ; Materials Analysis. ; Imaging systems. ; Nervous system Diseases. ; Nervous system Radiography. ; Neuroscience. ; Imaging Techniques. ; Neurological Disorders. ; Neuroradiology.
    Description / Table of Contents: Optical coherence tomography in brain gliomas detection and peritumoral white matter state evaluation -- Two Photon Fluorescence Lifetime Imaging of Reduced nicotinamide adenine dinucleotide in Brain Research -- Types of Raman Scattering Techniques for Neurodegenerative Diseases -- Drosophila brain advanced multiphoton imaging -- Myelin imaging -- Brainbow: Principle, Technique and Applications -- Photoacoustic Imaging of Brain -- Photodynamic therapy of brain diseases -- Advanced Magnetic Resonance Imaging (MRI) of Brain -- Indirect imaging -- Multimodal Noninvasive Imaging Strategies for Clinically Monitoring Degenerative Disorders of the Brain -- Machine learning approach in brain imaging -- Transgenic Brain mapping Techniques in Drosophila melanogaster -- Behavioural phenotyping to study cognitive and non-cognitive symptoms in the rodent model of Alzheimer's disease.
    Abstract: The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.
    Type of Medium: Online Resource
    Pages: XII, 257 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913525
    DDC: 612.8
    Language: English
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  • 91
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. The Auditory Cognitive Neuroscience of Speech Perception in Context -- 2. Subcortical Processing of Speech Sounds -- 3. Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology -- 4. A Parsimonious Look at Neural Oscillations in Speech Perception -- 5. Extracting Language Content From Speech Sounds: The Information Theoretic Approach -- 6. Speech Perception under Adverse Listening Conditions -- 7. Adaptive Plasticity in Perceiving Speech Sounds -- 8. Development of Speech Perception -- 9. Interactions Between Audition and Cognition in Hearing Loss and Aging.
    Abstract: This volume reviews contemporary developments in the auditory cognitive neuroscience of speech perception, including both behavioral and neural contributions. It serves as an important update on the current state of research in speech perception. The Auditory Cognitive Neuroscience of Speech Perception in Context Lori L. Holt, and Jonathan E. Peelle Subcortical Processing of Speech Sounds Bharath Chandrasekaran, Rachel Tessmer, and G. Nike Gnanateja Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology Yulia Oganian, Neal P. Fox, and Edward F. Chang A Parsimonious Look at Neural Oscillations in Speech Perception Sarah Tune, and Jonas Obleser Extracting Language Content From Speech Sounds: The Information Theoretic Approach Laura Gwilliams, and Matthew H. Davis Speech Perception under Adverse Listening Conditions Stephen C. Van Hedger, and Ingrid S. Johnsrude Adaptive Plasticity in Perceiving Speech Sounds Shruti Ullas, Milene Bonte, Elia Formisano, and Jean Vroomen Development of Speech Perception Judit Gervain Interactions Between Audition and Cognition in Hearing Loss and Aging Chad S. Rogers, and Jonathan E. Peelle .
    Type of Medium: Online Resource
    Pages: XVI, 252 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030815424
    Series Statement: Springer Handbook of Auditory Research, 74
    DDC: 612.8
    Language: English
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  • 92
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Behavioral Neuroscience.
    Description / Table of Contents: Part I Preclinical Research: Neuroendocrine Mechanisms of Social Bonds and Separation Stress in Rodents, Dogs, and Other Species -- Methods and Challenges in Investigating Sex-Specific Consequences of Social Stressors in Adolescence in Rats: Is It the Stress or the Social or the Stage of Development?- Social stress-induced neuroinflammation and mitochondrial dysfunction as a link to depression and cardiovascular disease comorbidity -- Mean Girls: Social Stress Models for Female Rodents -- Development of Mixed Anxiety/ Depression-Like State as a Consequence of Chronic Anxiety: Review of Experimental Data -- Unravelling the Neuroinflammatory Mechanisms Underlying the Effects of Social Defeat Stress on Use of Drugs of Abuse -- Social Stress and Aggression in Murine Models -- More or less: glucocorticoid roles in aggression -- Neurobiological Bases of Urges for Alcohol Consumption After Social Stress -- Epigenetics of Aggression -- Part II Human Research: Early Life Stress and Neurodevelopment in Adolescence: Implications for Risk and Adaptation -- Effects of Parenting Environment on Child and Adolescent Social-Emotional Brain Function -- The Stressed Brain: Neural Underpinnings of Social Stress Processing in Humans -- Social Acts and Anticipation of Social Feedback -- Clinical Outcomes of Severe Forms of Early Social Stress -- Childhood Violence Exposure, Inflammation, and Cardiometabolic Health -- Social Support Effects on Neural Stress and Alcohol Reward Responses -- Neural Underpinnings of Social Stress in Human Addiction.
    Abstract: Social stress has emerged as a research front in the neurosciences, and this volume highlights recent insights in brain mechanisms and methodological advances. The topics range from the evolutionary origins of coping with social challenges to neural mechanism-driven focus on novel treatment targets. The parallel presentation of work with animal models and human subjects is bound to be useful to a broad research community.
    Type of Medium: Online Resource
    Pages: VIII, 515 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031042560
    Series Statement: Current Topics in Behavioral Neurosciences, 54
    DDC: 612.8
    Language: English
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  • 93
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Psychiatry. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Section I. Anhedonia – History, Etiology, and Assessments -- 1. Historical Perspective -- 2. Clinical and Behavioral Assessments -- 3. Developmental Trajectories: Preclinical -- 4. Developmental Trajectories: Clinical -- 5. Genetics Contributions -- 6. Environmental Contributions -- Section II. Anhedonia in Psychiatric and Neurological Disorders -- 7. Depression and Bipolar Disorder -- 8. Schizophrenia -- 9. Substance Use Disorder -- 10. Nicotine Dependence -- 11. Posttraumatic Stress Disorder -- 12. Anxiety -- 13. Eating Disorders -- 14. Autism and Developmental Disorders -- 15. Neurodegenerative Disorders -- Section III. Reward Processing Systems in Anhedonia -- Reward Responsiveness -- 16. Pleasure -- 17. Anticipation -- Reward Valuation -- 18. Reward Value – Delay and Reward Magnitude -- 19. Effort/Motivation -- Reward Learning -- 20. Reward Prediction Error -- 21. Probabilistic and Reinforcement Learning -- Section IV. Treatments -- 22. Pharmacological Treatments for Anhedonia -- 23. Psychological Treatments for Anhedonia -- 24. Neurostimulation -- Section V. Special Topics -- 25. Inflammation and Anhedonia -- 26. Computational Modeling of Anhedonia -- 27. Anhedonia and Suicide.
    Abstract: Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia. Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (Part I), followed by a section on the role of anhedonia in psychiatric and neurological disorders (Part II). Using the RDoC Matrix as a guide, Part III presents chapters synthetizing preclinical and clinical findings on different reward processing subdomains (e.g., reward responsiveness, reward valuation, reward learning). Part IV is focused on selected special topics, including historical and current perspectives on the transdiagnostic nature and importance of social anhedonia, the role of inflammation in the pathophysiology of anhedonia, the use of computational modeling to “dissect” anhedonia and improve its understanding, and links between anhedonia and suicide. Finally, Part V includes chapters on pharmacological, psychological and neurostimulation treatments for anhedonia.
    Type of Medium: Online Resource
    Pages: XI, 535 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031096839
    Series Statement: Current Topics in Behavioral Neurosciences, 58
    DDC: 612.8
    Language: English
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  • 94
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nutrition   . ; Quantitative research. ; Nervous system Diseases. ; Neuroimmunology. ; Neuroscience. ; Nutrition. ; Data Analysis and Big Data. ; Neurological Disorders. ; Neuroimmunology.
    Description / Table of Contents: Chapter 1. Nutrigenomics; a broader concept -- Chapter 2. Gene-environment interaction -- Chapter 3. Gene-gut-brain - axis (gene–based personalized medicine) -- Chapter 4. Nutrigenomics of aging -- Chapter 5. Nutrigenomics and Mental health -- Chapter 6. Nutrigenomics and neurodevelopmental disorders -- Chapter 7. Nutrigenomics and Alzheimer’s disease -- Chapter 8. Nutrigenomics and Parkinson’s Disease -- Chapter 9. Nutrigenomics, nutrigenetics and big data -- Chapter 10. Nutrigenomics and Development -- Chapter 11. Early Child malnutrition and neurodevelopment -- Chapter 12. The emerging role of vit D deficiency and Parkinson’s Disease risk -- Chapter 13. Nutrigenomics and autophagy crosstalk -- Chapter 14. Nanoparticles in food additives and brain health.
    Abstract: This book highlights the effect of complex interactions between numerous genetic and environmental factors, including food intake, physical activity, age, and stress on brain physiology and function. It further discusses the mechanistic connection between nutrition and aging towards understanding the effect of the brain on longevity. The book also reviews the efficiency of nutraceutical compounds for treating and preventing of neurodevelopmental and neurodegenerative disorders. It also discusses the role of gut microbiota on the gut-brain axis and presents the role of nutrition in neurological inflammatory diseases.
    Type of Medium: Online Resource
    Pages: VII, 234 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692055
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 95
    Keywords: Neurosciences. ; Psychobiology. ; Human behavior. ; Pharmacology. ; Psychiatry. ; Pain medicine. ; Neuroscience. ; Behavioral Neuroscience. ; Pharmacology. ; Psychiatry. ; Pain Medicine.
    Description / Table of Contents: CLINICAL PROFILE AND TREATMENTS -- ADHD in children and adults: diagnosis and prognosis -- Treatment strategies -- Psychostimulants – treatment efficacy and problems -- Recent developments and future options for pharmacological treatments for ADHD -- GENETICS -- Genetics of ADHD (including CNVs) -- Genes , cognitive function and ADHD -- Epigenetics and ADHD -- CO-MORBIDITY -- ADHD and comorbid depression -- ADHD and autism -- Aggression and ADHD -- Obesity and ADHD (+ cytokines?) -- Sleep circadian rhythms and ADHD -- Substance misuse -- ASSESSING BRAIN FUNCTION / DYSFUNCTION -- EEG and ADHD (the skeptical view) -- Update on imaging – with connectivity -- Visual processing substrates for ADHD -- Cortical microstructure / connectivity -- ANIMAL AND IN VITRO STUDIES -- Critique of animal models -- Update on circuits for impulsive behaviour -- Zebrafish -- Update on DA transporter and ADHD -- Arousal, noradrenaline and ADHD -- FUTURE DIRECTIONS -- Stem cells for disease modelling -- Microbiome and ADHD -- Adult ADHD.
    Abstract: New Discoveries in the Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest developments in preclinical and clinical research of Attention Deficit Hyperactivity Disorder. As well as updating key chapters that were included in an earlier edition, this volume includes some new topics that are attracting a great deal of interest and point the way to new and promising directions for future research. The chapters follow five main themes: Current perspectives on the clinical profile of ADHD and its treatment, common co-occurring conditions, neurobiological studies examining brain function and genetics, animal and in vitro studies, and future directions. This combination of topics emphasises the translational relevance and validity of preclinical research so as to enable a better understanding of ADHD and to highlight the promising strategies for developing new treatments.
    Type of Medium: Online Resource
    Pages: VIII, 501 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031118029
    Series Statement: Current Topics in Behavioral Neurosciences, 57
    DDC: 612.8
    Language: English
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  • 96
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nervous system Diseases. ; Cognitive neuroscience. ; Developmental neurobiology. ; Nutrition   . ; Neuroscience. ; Neurological Disorders. ; Cognitive Neuroscience. ; Development of the Nervous System. ; Nutrition.
    Description / Table of Contents: Chapter 1. Micronutrients and Neurogenesis -- Chapter 2. Vit-E and Cognitive functions: What is the Interplay? -- Chapter 3. Microbiome and micronutrients -- Chapter 4. Iodine and Brain -- Chapter 5. Tocotrienol and Brain -- Chapter 6. Micronutrients and Depression -- Chapter 7. Micronutrients and Epilepsy -- Chapter 8. Iron Deficiency and brain cognitive functions -- Chapter 9. Micronutrients and PD -- Chapter 10. Malnutrition of Micronutrients and the brain disorders -- Chapter 11. Connections between micronutrients, cerebral monoamines and related brain disorders -- Chapter 12. Micronutrients and Autism -- Chapter 13. Edible Bird’s Nest as Brain Food -- Chapter 14. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Traumatic Brain Injury? -- Chapter 15. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Alzheimer’s Disease? -- Chapter 16. Nutrigenomics and Brain.
    Abstract: This book comprehensively reviews the relationship between micronutrients and brain in health and diseases. It explains the relationship between micronutrients and brain functions, neurogenesis, and cognitive functions. The book also explores the relationship between micronutrients and brain disorders including depression, epilepsy, PD, and Autism. It further explores the recent advancements in understanding the important role of micronutrients as therapeutics in various brain disorders like TBI and AD. Lastly, it presents an overview of micronutrients as neuroprotective agents along with the main principles of nutrigenomics.
    Type of Medium: Online Resource
    Pages: XVII, 308 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811664670
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 97
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Cognitive psychology. ; Neuropsychology. ; Psychiatry. ; Philosophy of mind. ; Neurology . ; Neuroscience. ; Cognitive Psychology. ; Neuropsychology. ; Psychiatry. ; Philosophy of Mind. ; Neurology.
    Description / Table of Contents: Learning the Languages -- Humanity’s Search for Mind and the Subject: A Brief Review of the Evolution of Neuropsychobiology -- An “Ideographic,” Suprapersonal Language of Rules and Universal Symbols: Alwyn Scott and Nonlinear Dynamics -- A “Demotic,” First-Person Language of the Individual and the Social System: Apuleius and the Myth of Psyche -- The Language of the Objective Observer: Gerald Edelman and Neurodarwinism: Antonio Damasio and the Feeling of Knowing -- Seeking the Understanding -- Consciousness -- The Unconscious -- The Database -- Affectivity -- The Neural/Mental Gap: Intuition, Self and Ego, a Trilingual Map -- Applying the Knowledge -- The Three Languages and Science: A New Scientific Paradigm? -- The Three Languages and Treatment -- The Psychotherapeutic Dialogue: Intersubjectivity -- The Role of a New Science for Psyche Upon Society and Culture.
    Abstract: The study of the brain-mind complex has been hampered by the dichotomy between objective biological neuroscience and subjective psychological science. The two antithetical avenues of research are partly responsible for the failure to unravel the transformation of neural events into mental images: how matter becomes imagination, and vice versa; is the brain’s consciousness equivalent to Ego consciousness? Is the ego the self? In its new and updated edition, “The Rosetta Stone of the Human Mind: Three Languages to Integrate Neurobiology and Psychology” illustrates how the simultaneous use of the languages of neurobiology, of mathematics, and of the humanities, enriches the understanding of the neural and mental realms and adds new dimensions to our perception of neuropsychological events. Dr. Sanguineti shows how the two seemingly dichotomous approaches are similar in what they describe, and he explores how the awareness and application of these perspectives are helpful in getting a deeper theoretical grasp on major mental events, giving us a better understanding of individual minds, and fostering a more integrated therapeutic intervention. The intended readers include neuroscientists, psychiatrists, psychologists, and anyone interested in the human mind. Describes a model integrating biological neuroscience principles, subjective psychological science, and nonlinear physics and mathematics Offers a wide-ranging, holistic exploration of the mind and its conscious and unconscious realms, using myth, art, philosophy, neurobiology and basic sciences Introduces the future new paradigm for emergent science, the Poem, to replace the outdated classical reductionistic paradigm of the Machine.
    Type of Medium: Online Resource
    Pages: XXII, 167 p. 25 illus., 6 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030864156
    DDC: 612.8
    Language: English
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  • 98
    Keywords: Neurosciences. ; Proteins. ; Nervous system Diseases. ; Genetics. ; Neuroscience. ; Proteins. ; Neurological Disorders. ; Genetics.
    Description / Table of Contents: Chapter 1. Proteins Commonly Linked to Autism Spectrum Disorder -- Chapter 2. Protein Aggregation and Recycling -- Chapter 3. Neuron Membrane and Trafficking Protein Kinases (PKA&B) involved in ASD -- Chapter 4. Proteomic profiling in children with ASD -- Chapter 5. Molecular Protein biomarkers for developing diagnostics and therapeutic interventions.Gene Regulation in Autism. OR Neurodevelopmental Epigenomics -- Chapter 6. Chromatin and Epigenetic Regulation in ASD -- Chapter 7. Autism and the Scaffolding Protein Neurobeachin -- Chapter 8. Genomic Profiling in ADHD subjects -- Chapter 9. ADHD and Epigenetics Regulation -- Chapter 10. Proteomic Approach in ADHD -- Chapter 11. DHD and the Dopamine Transporter (DAT) -- Chapter 12. Protein Kinases involved in ADHD -- Chapter 13. ADHD and Cell Adhesion Molecule 1 – CAM 1 (CADM1 gene) -- Chapter 14. ASD and Cell Adhesion Molecule Astrotactin -- Chapter 15. Possible therapeutic interventions through proteins in ADHD.
    Abstract: This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.
    Type of Medium: Online Resource
    Pages: XV, 339 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811597817
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 99
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neurology . ; Neuropsychology. ; Pharmacology. ; Neuropharmacology. ; Psychiatry. ; Neuroscience. ; Neurology. ; Neuropsychology. ; Pharmacology. ; Neuropharmacology. ; Psychiatry.
    Description / Table of Contents: Treatments Against Glutamatergic Excitotoxicity in Ischemic Stroke -- Definitions and Concepts of Stress -- Role of Glutamatergic Neurotransmission in the Pathophysiology of Stress-Related Disorders and Chronic Stress Response -- Current Glutamatergic Treatments and Future Directions for Glutamate-Based Management of Chronic Stress and Stress-Related Disorders -- The Role of the Glutamate System in Posttraumatic Stress Disorder and Glutamate-Based Treatments -- Glutamate in Migraine Neurobiology and Treatment -- Astrocyte Glutamate Transporter EAAT2 in Alzheimer Dementia -- The Glutamatergic System as a Target for the Development of New Pharmacological Treatments of Bipolar Disorder -- CNS Glutamate in Impulsive Aggression -- Glutamatergic Treatments for Parkinsons' Disease -- The Modulation of Glutamatergic Signaling as a Potential Therapeutic Strategy for Major Depression -- Glutamate-Based Treatment for Amyotrophic Lateral Sclerosis/Motor Neuron Disease -- Modulation of Glutamate for Chronic Pain Management -- Pharmacological Role of Glutamate Transporters in Substance Use Disorders -- Glutamate in Multiple Sclerosis: From Pathophysiology to Treatments -- The Role of Glutamate Dysregulation in the Etiology of ADHD -- Glutamate, Glutamatergic Drugs and Schizophrenia -- Glutamate and Epilepsy: An Insight from Temporal Lobe Epilepsy -- Glutamate Function in Anxiety Disorders and OCD: Evidence from Clinical and Translational Studies -- Modulators of Glutamatergic Signaling as Potential Treatments for Autism Spectrum Disorders.
    Abstract: This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD), Posttraumatic Stress Disorder (PTSD), Alzheimer’s Dementia, Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD), Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple Sclerosis, Parkinson’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders. Moreover, the book includes an extensive overview of glutamatergic treatments already available on the market, and those which are currently in pharmaceutical drug development pipelines. The primary beneficiaries will be neurology and psychiatry specialists and residents, neuroscientists, neuropharmacologists, pharmaceutical industry and clinical research organization professionals, academics, and clinicians working with psychiatric and neurological patients with comorbidities such as cardiologists, pulmonologists, and endocrinologists. This book will also appeal to psychiatry and neurology subspecialists and clinicians working in neuroscience labs seeking an easy-to-understand yet comprehensive overview of contemporary evidence-based clinical insights backed by basic science (preclinical) research evidence. Given its scope, the book is also a unique and indispensable resource for both preclinical and clinical neuroscientists, medical advisors, and clinical research specialists in the pharmaceutical industry. In addition, it will appeal to neuroscience and neuropsychopharmacology students and guide them through the complexities of glutamate involvement in the pathophysiology of the most common debilitating brain diseases with high unmet medical needs.
    Type of Medium: Online Resource
    Pages: XXXV, 600 p. 43 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874803
    DDC: 612.8
    Language: English
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  • 100
    Keywords: Neurosciences. ; Neural circuitry. ; Bioinformatics. ; Computer science. ; Neuroscience. ; Neural Circuits. ; Computational and Systems Biology. ; Computer Science.
    Description / Table of Contents: PART I. Cellular Scale -- Chapter 1. Modelling Neurons in 3D at the Nanoscale -- Chapter 2. Modelling Dendrites and Spatially-Distributed Neuronal Membrane Properties -- Chapter 3. A User's Guide to Generalized Integrate-and-Fire Models -- Chapter 4. Neuron-glia Interactions and Brain Circuits -- Chapter 5. Short-term Synaptic Plasticity: Microscopic Modelling and (some) Computational Implications -- PART II. Molecular Scale -- Chapter 6. The Mean Field Approach for Populations of Spiking Neurons -- Chapter 7. Multidimensional Dynamical Systems with Noise -- Chapter 8. Computing Extracellular Electric Potentials from Neuronal Simulations -- Chapter 9. Bringing Anatomical Information into Neuronal Network Models -- PART III. Network Scale -- Chapter 10. Computational Concepts for Reconstructing and Simulating Brain Tissue -- Chapter 11. Reconstruction of the Hippocampus -- Chapter 12. Challenges for Place and Grid Cell Models -- Chapter 13. Whole-Brain Modelling: Past, Present, and Future.
    Abstract: This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. .
    Type of Medium: Online Resource
    Pages: XII, 359 p. 115 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030894399
    Series Statement: Cellular Neuroscience, Neural Circuits and Systems Neuroscience, 1359
    DDC: 612.8
    Language: English
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