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  • 2020-2024  (66)
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  • 615  (25)
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  • 1
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Description / Table of Contents: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Abstract: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Type of Medium: Online Resource
    Pages: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811525179
    Series Statement: Advances in Experimental Medicine and Biology, 1177
    DDC: 615
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    DDC: 615
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human physiology. ; Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human Physiology.
    Description / Table of Contents: Successful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
    Abstract: Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .
    Type of Medium: Online Resource
    Pages: VII, 180 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030580049
    Series Statement: Current Topics in Microbiology and Immunology, 428
    DDC: 615
    Language: English
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  • 4
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: 1 Principles of pharmaceutical analysis in drug stability and chemical kinetics -- 2 Guidelines for drug stability and stability testing -- 3 Chemical kinetics and its applications in drug stability -- 4 Methods and protocols for drug stability studies -- 5 Physical basis of degradation of pharmaceutical products -- 6 Role of microbiological degradation on drug stability -- 7 Role of decomposition on drug stability -- 8 Role of catalysis in drug stability -- 9 Analytical techniques for the assessment of drug stability -- 10 Stability of pharmaceutical products -- 11 Role of kinetic models in drug stability -- 12 Stability studies of vaccines -- 13 Stability studies of proteinous compounds -- 14 Stability studies of extemporaneous pharmaceutical products -- 15 Stability studies of parenteral products -- 16 Stability studies of solid dosage forms.
    Abstract: This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. .
    Type of Medium: Online Resource
    Pages: XIV, 284 p. 22 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811564260
    DDC: 615
    Language: English
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  • 5
    Keywords: Pharmacology. ; Pharmacy. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Medicinal Chemistry.
    Description / Table of Contents: Abelmoschus maschatus -- Abrus precatorius -- Abutilon indicum -- Acacia catechu -- Acacia nilotica (A. arabica) -- Achillea millefolium -- Achyranthes aspera -- Aconitum napellus -- Acorus calamus -- Adiantum venustum (Adiantun capillus-veneris) -- Aegle marmelos -- Agrimonia eupatorium.-Alhagi maurorum -- Alkanna tinctoria -- Allium cepa -- Allium sativum -- Aloe vera -- Alpinia galangal -- Alpinia officinarum -- Alstonia scholaris -- Althaea officinalis -- Ammi majus -- Anacardium occidentale -- Anacyclus pyrethrum -- Andrographis paniculata -- Anethum graveolens -- Anthemis nobilis -- Apium graveolens -- Argemone Mexicana -- Aristolochia bracteolata -- Aristolochia fontanesii (A. longa) -- Aristolochia indica -- Aristolochia rotunda -- Artemisia absinthium -- Artemisia vulgaris -- Asparagus adscendens -- Asparagus officinalis -- Asparagus racemosus -- Atropa belladonna -- Azadirachta indica -- Bacopa monnieri -- Bauhinia tomentosa -- Berberis Aristata -- Berberis vulgaris -- Bombyx mori -- Borago officinalis -- Boswellia serrata -- Brassica nigra -- Butea monosperma -- Caccinia macranthera var. glauca (C. glauca) -- Caesalpinia bonduc (Caesalpinia bonducella) -- Cannabis sativa -- Capparis spinosa -- Cardiospermum halicacabum -- Carthamus tinctorius -- Carum carvi -- Cassia fistula -- Catharanthus roseus -- Celastrus paniculatus -- Centaurea behen -- Centella asiatica -- Chamaecrista absus (Cassia absus) -- Chamaemelum nobile (Anthemis nobilis) -- Cheilocostus speciosus (Costus Speciosus) -- Cichorium intybus -- Cinnamomum camphora -- Cinnamomum cassia -- Cinnamomum verum (C. zeylanicum) -- Citrullus colocynthis -- Clitoria ternatea -- Colchicum autumnale -- Colchicum luteum -- Commiphora gileadensis (C. opobalsamum) -- Commiphora myrrha -- Commiphora wightii (C. mukul) -- Convolvulus scammonia -- Cotoneaster nummularius -- Crocus sativus -- Croton tiglium -- Cullen corylifolium (Psoralea corylifolia) -- Cuminum cyminum -- Curcuma aromatica -- Curcuma longa -- Curcuma zedoaria -- Cuscuta chinensis -- Cuscuta reflexa -- Cydonia oblonga -- Cymbopogon schoenanthus -- Cyperus rotundus -- Datura stramonium -- Delphinium denudatum -- Dolichousnea longissimi (Usnea longissima) -- Doronicum pardalianches -- Embelia ribes -- Euphorbia hirta -- Euphorbia resinifera -- Ferula assa-foetida -- Ficus carica -- Ficus racemosa -- Foeniculum vulgare -- Fumaria officinalis -- Gentiana lutea -- Glycyrrhiza glabra -- Gymnema sylvestre -- Helleborus niger -- Hemidesmus Indicus -- Hibiscus rosa-sinensis -- Holarrhena pubescens (Holarrhena antidysenterica) -- Hyoscyamus niger -- Hyssopus officinalis -- Illicium verum -- Iris germanica -- Juniperus communi -- Justicia adhatoda (Adhatoda vasica) -- Lactuca sativa -- Lavandula stoechas -- Lawsonia inermis -- Lepidium sativum -- Linum usitatissimum -- Lupinus albus -- Malva sylvestris -- Marrubium vulgare -- Matricaria chamomilla -- Melia azedarach -- Melilotus officinalis -- Melissa officinalis -- Mesua ferrea -- Momordica charantia -- Moringa oleifera -- Myristica fragrans -- Myrtus communis -- Nageia nagi -- Nepeta cataria -- Nigella sativa -- Ocimum basilicum -- Ocimum gratissimum -- Ocimum tenuiflorum (Ocimum sanctum -- Operculina turpethum -- Paeonia emodi -- Pandanus odorifer (Pandanus Odoratissimus) -- Papaver somniferum -- Persicaria bistorta -- Phyllanthus emblica (Emblica officinalis) -- Picrorhiza kurroa -- Pimpinella anisum -- Piper cubeba -- Piper nigrum -- Pistacia lentiscus -- Plantago major -- Plantago ovata -- Plumbago zeylanica -- Polygonum aviculare -- Portulaca oleracea -- Quercus infectoria -- Rauvolfia serpentina -- Rheum emodi -- Rheum officinale -- Ricinus communis -- Rubia cordifolia -- Rumex vesicarius -- Ruta graveolens -- Salix caprea -- Salvia officinalis -- Santalum album -- Saussurea lappa -- Semecarpus anacardium -- Senna alexandrina -- Senna occidentalis -- Senna tora -- Sida cordifolia -- Smilax china;- Solanum americanum (S. nigrum) -- Sterculia urens -- Strychnos nux-vomica -- Swertia chirata -- Symplocos racemosa -- Syzygium cumini (Eugenia jambolana) -- Tamarindus indica -- Taraxacum officinale -- Taxus baccata -- Tephrosia purpurea -- Terminalia bellirica -- Terminalia chebula -- Thymus vulgaris -- Tinospora cordifolia -- Trachyspermum ammi (Ptychotis coptica) -- Tribulus terrestris -- Trigonella foenum-graecum -- Tussilago farfara -- Valeriana jatamansi (Nardostachys jatamansi) -- Verbena officinalis -- Vernonia anthelmintica (Baccharoides anthelmintica) -- Vigna unguiculata (Dolichos biflorus) -- Viola odorata -- Viscum album -- Withania somnifera -- Wrightia tinctoria -- Zingiber officinale -- Zingiber zerumbet -- Ziziphus jujuba -- Abbreviations -- Glossary -- Ayurvedic Terms of Diseases -- List of Referenced Books -- Index.
    Abstract: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.
    Type of Medium: Online Resource
    Pages: XXX, 2156 p. 199 illus., 198 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030168070
    DDC: 615
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Description / Table of Contents: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Abstract: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Type of Medium: Online Resource
    Pages: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030328573
    Series Statement: Human Perspectives in Health Sciences and Technology, 2
    DDC: 615
    Language: English
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  • 7
    Keywords: Pharmacology. ; Immunology. ; Pharmacology. ; Immunology.
    Description / Table of Contents: Preface Chapter 1: Overview of the Immune System and its Pharmacological Targets -- Chapter 2: Modulation of the Innate Immune System -- Chapter 3: Modulation of the Adaptive Immune System -- Chapter 4: Respiratory Disorders of the Immune System and their Pharmacological Treatment -- Chapter 5: Inflammation of the Skin and its therapeutic topics -- Chapter 6: Inflammatory Diseases of the Gastrointestinal Tract and Pharmacological Treatments -- Chapter 7: Mechanisms of Autoimmunity and Pharmacologic Treatments -- Chapter 8: Transplantation: Immunologic Principles and Pharmacologic Agents -- Chapter 9: Immunopathogenesis, Immunization, and Treatment of Infectious Diseases -- Chapter 10: Cancer Immunotherapy.
    Abstract: Medicine has entered a golden age in which therapeutic agents are becoming widely available due to advances in basic science and technology. As such, many drugs have been developed that target inflammatory processes and/or the immune system. This book is intended for health professionals examining the modulation of inflammation by immunotherapeutic drugs. The immune system fills the primordial role of host defense and resistance to infections with pathogenic microorganisms. Several hematopoietic-derived cells constituting the innate and adaptive immune systems cooperate to provide barriers for microbial colonization and/or promote pathogen destruction within the host. Conversely, many immune cells are also involved in the pathogenesis and propagation of chronic inflammatory diseases. The beginning of this book details various components of the immune system including the cell types, lymphoid tissues, soluble cytokines and surface molecules that are essential for host defense. Breakdowns in immune tolerance, or dysregulated immune responses to antigens derived from self tissues or innocuous sources, can lead to the development of autoimmunity or chronic inflammatory diseases. Pathophysiologic roles for the immune system are detailed in corresponding chapters on autoimmunity, epithelial surfaces (lungs, skin, intestine), and transplantation, with special emphasis placed on immunotherapeutic drug targets. The last section of the book focuses on treatments that stimulate our immune system to specifically target and fight infectious diseases and cancer. In each chapter, the medications used to treat various diseases/conditions in terms of their mechanism of action and other pharmacologic properties are discussed in detail. Chapters begin with a table showing drug names and classifications. The importance of basic science and clinical trials cannot be understated in the context of drug development. As such, the discovery of certain medications that had a lasting impact in medicine and pharmacy are highlighted in chapter subsections named “Bench to Bedside.” Several clinical applications of immunotherapeutic drugs are described within end-of -chapter case studies including practice questions. The Pharmacology of Immunotherapeutic Drugs is a reference for immunologists and clinicians (medical doctors, pharmacists, nurses) examining the modulation of inflammatory processes by a variety of medications targeting the cells and mediators of our immune system.
    Type of Medium: Online Resource
    Pages: XIX, 399 p. 118 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030199227
    DDC: 615
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Virology. ; Immunology. ; Pharmacology. ; Virology. ; Immunology.
    Description / Table of Contents: Rabies Life Cycle, Transmission and Pathogenesis -- History of Rabies and Rabies Vaccines -- Rabies vaccines for wildlife -- Human Rabies Vaccines -- Rabies vaccines, prophylactic, Peru -- Rabies Prevention in Asia: Institutionalizing Implementation Capacities -- Passive Immunity in Rabies Prophylaxis -- Rabies Little Virus Against Powerful Innate Immunity -- Novel Rabies Vaccines -- Assessing the potency of inactivated veterinary vaccines and oral live vaccines against rabies -- WHO Perspective on Rabies.
    Abstract: This book reviews the recent advances in rabies research and rabies vaccine development. The reader is introduced to biology and pathology of the virus, causing agents and the history of rabies vaccination. The book presents regional rabies prophylaxis programs and discusses vaccination strategies for wildlife and humans. Further, innate immune response as well as antibody response to rabies are examined. All chapters are written by renowned experts in rabies research, some of them part of the WHO Collaboration Centre for Rabies Surveillance and Research. The book targets researchers and health professionals working in Virology, Veterinary Medicine and Biomedicine. .
    Type of Medium: Online Resource
    Pages: VII, 205 p. 15 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030210847
    DDC: 615
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Forensic sciences. ; Medical jurisprudence. ; Pharmacology. ; Forensic Science. ; Forensic Medicine.
    Description / Table of Contents: Part 1: Introduction -- Post Mortem Forensic Toxicology -- Human Performance Toxicology -- Drug-Facilitated Sexual Assault -- Forensic Drug Testing -- Performance enhancing Drug Testing -- Drug Testing in Pain Management -- Pharmacokinetics and Pharmacodynamics -- Part II. Specimen Preparation -- Spectrophotometry -- Chromatography -- Derivatization -- Immunoassy -- Mass Spectrometry -- Quantitation -- Method Validation -- Measurement Uncertainty and Traceability -- Statistics in Forensic Toxicology -- Part III Analytes -- Alcohol -- Benzodiazapines -- Gammahydroxybutyric acid,- Miscellaneous Central Nervous System Depressants -- Opioids -- Cocanie -- Cannabis -- Amphetamines-Sympathomimetic Amines,- Hallucinogens and Psychedelics -- Antidepressants and Neuroleptics -- Miscellaneous Therapeutic Drugs -- Carbon Monoxide/Cyanide -- Inhalants -- Metals -- Part III Special Topics -- Stability of Drugs of Abuse in Biological Systems -- Postmortem Redistribution of Drugs -- Postmortem Clinical Testing -- Pharmacogenomics -- Hair Drug Testing -- Oral Fluid Testing -- Meconium Drug Testing -- Drugs in Embalmed Tissues.
    Abstract: The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner’s offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.
    Type of Medium: Online Resource
    Pages: XIII, 691 p. 188 illus., 23 illus. in color. , online resource.
    Edition: 5th ed. 2020.
    ISBN: 9783030429171
    DDC: 615
    Language: English
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  • 10
    Keywords: Pharmacology. ; Pharmacy. ; Pharmacology. ; Pharmacy.
    Description / Table of Contents: Introduction -- History of CROs: Including CRO Snapshots and a CRO Genealogy Chart -- The Pharmaceutical Development Process & Testing Requirements -- The Medical Device Development Process & Testing Requirements -- Functions and Types of CROs -- Labs in China and India -- Selection of CROs -- Study Directors and PIs -- Nuts and Bolts of Study Performance SCG/CBS -- Electronic Reporting Requirements (SEND & eCTD) -- Study and Project Monitoring -- Contracting, Pricing, and Cost of Works Performed by CROs -- Consultants and their Role -- Building Relationships: Maximizing your return on Expectations with a CRO -- Common Problems and their Solutions -- Appendices: A Toxicology Labs B Medical Device Labs C Phase I Labs D Analytical Labs E GMP Contract Facilities F Formulation G Dosage Forms H Clinical Testing I Regulatory Services J Forms and Checklists -- K Specialized Services -- L Consultants Known to be In-Practice -- Index. .
    Abstract: This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics: · The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went. · Study directors and principal investigators. · The nuts and bolts of study performance. · Electronic reporting requirements – SEND and eCTD (required for NDA, BLA, ANDA, and IND submissions). · Consultants and their roles. · An expanded examination of common problems and their solutions. This book boasts complete directories to the global universe of operating labs – where they are, how to contact them, and what they do (including special capabilities). Additionally, checklists for qualifying labs and manufacturing facilities – and for auditing studies and projects at such facilities – are included. It is directed at those in industry (specifically directed at those working for companies using CRO services) but will also be of interest to scientists or administrators working in research organizations themselves. In this case, the contents of this new work are essential to the target reader because the work, regulations, and actors (CROs) have evolved and changed at a rapid pace in the 10 years since the earlier volume that the author published. Likewise, the companies using these services have come to all be almost completely dependent on outsourcing. The earlier texts remain the only source of their kind (paper or electronic) on the field and the only noncommercial guide to the global industry and this volume provides a complete update.
    Type of Medium: Online Resource
    Pages: XIII, 519 p. 19 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030430733
    DDC: 615
    Language: English
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  • 11
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Surgery. ; Dentistry. ; Veterinary medicine. ; Neurology . ; Orthopedic surgery. ; Pharmacology. ; Surgery. ; Dentistry. ; Veterinary Science. ; Neurology. ; Surgical Orthopedics.
    Description / Table of Contents: 1. History of development of botulinum toxin therapy in medical and surgical fields -- 2. Molecular structure and mechanisms of action of botulinum toxins as it pertains to clinical symptoms -- 3. Types of toxins in commercial use, their similarities and differences -- 4. A review of current Botulinum toxin treatment indications in medical field. - 5. Mechanisms of Analgesic effects of botulinum neurotoxins -- 6. Botulinum toxin treatment in Head and neck surgery -- 7. Botulinum toxin treatment of thoracic and abdominal surgery -- 8. Botulinum Toxin A in Abdominal Wall Reconstruction -- 9. Use of Botulinum toxin A in post-mastectomy breast reconstruction -- 10. Botulinum Toxins for Treatment of Pain in Orthopedic Disorders -- 11. Botulinum toxin for pediatric patients, Who? For what? When? -- 12. Botulinum Toxin Treatment in Plastic Surgery -- 13. Botulinum Toxin Treatment in Ophthalmology and Ophthalmic surgery -- 14. Botulinum Toxin Treatment in Gastrointestinal Disorders -- 15. Botulinum Toxin Treatment in Urological Disorders -- 16. Botulinum Toxin Treatment in Dentistry -- 17. Botulinum toxin treatment in Veterinary Medicine - Clinical implications -- 18. Future Perspectives of Botulinum Toxin Application In Dentistry.
    Abstract: All books on the market which have been written on the subject of botulinum toxin therapy focus on treatment of hyperactive movement disorders, autonomic dysfunction (bladder, sweat and salivary glands) and some pain indications (migraine). Reference to pre-or post -surgical indications are brief and often out-dated. No book has information on dentistry or veterinary medicine. This book provides up-to-date information on botulinum toxin therapy in surgical fields. It is also the only book in the market that provides information on botulinum toxin therapy in dentistry and veterinary medicine and furnishes the latest information. Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine appeals to many disciplines including surgery, dentistry and veterinary medicines well as appealing to neurologists and internists.
    Type of Medium: Online Resource
    Pages: VIII, 398 p. 70 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506919
    DDC: 615
    Language: English
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  • 12
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Therapeutics. ; Pharmacology. ; Therapeutics.
    Description / Table of Contents: Nano-technological Platforms and Manipulations for the Emerging Ocular Manifestations -- Phytonanomedicines as Topical Alternatives for the Treatment of Skin Cancer -- Nano-sized Labile and Particulate Ingredients in Topical Formulations: A Strategic Approach Against Photoageing and Photocarcinogenisis -- Application of Biocompatible Nanocarriers in Glaucoma: Challenges and Advances -- Nano-carriers for Natural Therapeutics in the Management of Neuropathic Pain -- Advances in the Delivery of Therapeutic Peptides -- Nanoformulations and Their Role in Colon Targeting -- Theranostic Nanoformulations: Merging Diagnostics and Therapeutics -- The Role of Nanoformulations in Nose-To-Brain Drug Delivery -- Cubic Lyotropic Liquid Crystalline Nanostructures: A Versatile Platform for Delivery -- Preformulation Challenges: The Concept Behind the Selection, Design, and Preparation of Nanoformulations -- Nanoethosomes for Topical Fungal Therapeutics -- Comparison of Therapeutic Efficiency of Nanoformulations of Curcumin vs. Tetrahydrocurcumin in Various Disorders -- Nanomedicinal Approaches of Phytotherapeutics to Treat Alzheimers Disease -- Nanoparticulate Approaches to Exploit the Pathophysiology of Rheumatoid and Osteoarthritis -- Emerging Nanotechnology in Chronic Respiratory Diseases -- Conventional and Non-conventional Approaches of Site-specific Targeting of Therapeutics in Some Infectious Diseases and Metabolic Disorders -- Nanoformulations in Human Health Conditions: The Paradigm Shift -- Magnetic Nanoparticles Nanoformulation for Alternative Therapy of Cancer by Super-paramagnetic Hyperthermia -- Nano-weapons Against Tuberculosis -- Drug-Excipient Interactions in Nanoformulations with Special Focus on Impurity Control per ICH guidelines.
    Abstract: This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.
    Type of Medium: Online Resource
    Pages: XVIII, 548 p. 106 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030418588
    DDC: 615
    Language: English
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  • 13
    Keywords: Geology. ; Mineralogy. ; Geology. ; Mineralogy.
    Description / Table of Contents: Barmer basin -- Deccan Traps -- Lesser Himalaya -- Ladakh Himalaya -- Aravalli.
    Abstract: This book presents more than 600 eye-catching structural geological photographs and explanatory descriptions, from different Indian terrains. This book will enable easy identification of deformation features, one of the most important tasks in structural geology at the meso- and micro-scales. The book focuses on ductile and brittle shear sense indicators. This book suits for the undergraduate and graduate geoscience students. The book will be of considerable interest to tectonicians and structural geologists, given the enormous international importance of Indian terrains for exploration and other purposes.
    Type of Medium: Online Resource
    Pages: VII, 623 p. 609 illus., 608 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811398254
    DDC: 551
    Language: English
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  • 14
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Water. ; Hydrology. ; Environmental management. ; Bioclimatology. ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Environmental monitoring. ; Water. ; Environmental Management. ; Climate Change Ecology. ; Freshwater and Marine Ecology. ; Pollution. ; Environmental Monitoring.
    Description / Table of Contents: Foreword -- Preface -- Chapter 1 Introduction.-Chapter 2 Atmospheric Regime and Terrain Characteristics -- Chapter 3 Rivers -- Chapter 4 Springs -- Chapter 5 Snow Cover -- Chapter 6 Lakes and Reservoirs -- Chapter 7 Wetlands -- Chapter 8 Groundwater -- Chapter 9 Challenges on Water Resources -- Chapter 10 Proposed Solutions -- Glossary.
    Abstract: Water has become a challenging resource that many countries worldwide are concerned with. Thus, water is often linked with health, society development, national income and even international geo-politics. Sometimes, water resources are unavailable, but successful management involves developing approaches and projects to assure water supply. However, there are some countries with available water resources, but unsatisfactory management, and thus complain about water supply becoming a national problem. This situation is prevalent in Lebanon, a country characterized by abundant water resources whether on the surface or sub-surface. It is a paradox that there is still imbalance in water supply/demand in Lebanon, and water resources are now under stress due to chaotic use. This has been exacerbated by the oscillating climatic conditions, increased population and improper management. Therefore, people receive less than one-third of their water needs, and most water supplied is of poor quality. The current status shows a descending trend. Undoubtedly, if the water sector in Lebanon continues this way, we should anticipate unfavourable (and may be severe) consequences. Many studies have been conducted on water and related disciplines in Lebanon; however, all of them focus on specific themes and sometimes defined regions. Nevertheless, the occurred changes on the influencers (natural and man-made) have not been considered. This book is the first of its type for Lebanon, and it shows all aspects of water resources with updated measurements and findings obtained by adopting new techniques. It diagnoses in-depth the major elements of water flow/storage mechanism that have never been covered in such a comprehensive manner before. Also, this book introduces and analyses the existing challenges and proposes solutions. It represents a comprehensive investigation of the water resources in Lebanon.
    Type of Medium: Online Resource
    Pages: XIII, 229 p. 87 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030487171
    Series Statement: World Water Resources, 7
    DDC: 551.48
    Language: English
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  • 15
    Keywords: Geology. ; Environmental management. ; Power resources. ; Environment. ; Water. ; Hydrology. ; Geology. ; Environmental Management. ; Natural Resource and Energy Economics. ; Environmental Sciences. ; Water.
    Description / Table of Contents: Chapter 1. Sustainable Groundwater Management in France and Australia: Setting Extraction Limits, Allocating Rights and Reallocation -- Chapter 2. Groundwater in France: Resources, Use and Management Issues -- Chapter 3. Groundwater Policy in France: From Private to Collective Management -- Chapter 4. Groundwater Management Planning at the River Basin District Level: Comparative Analysis of the Adour-Garonne and Loire-Bretagne River Basins -- Chapter 5. Lessons from Twenty Years of Local Volumetric Groundwater Management: The case of the Beauce Aquifer, Central France -- Chapter 6. Groundwater in Australia: Occurrence and Management Issues -- Chapter 7. The Evolution of Groundwater Management Policy in the States of Australia -- Chapter 8. Developing a Coordinated Groundwater Management Plan for the Interstate Murray-Darling Basin -- Chapter 9. Information Systems for Sustainable Management of Groundwater Extraction in France and Australia -- Chapter 10. The Challenge of Making Ground-water Visible: A Review of Communication Approaches and Tools in France -- Chapter 11. Conceptual Approaches, Methods and Models used to Assess Abstraction Limits for Unconfined Aquifers in France -- Chapter 12. Setting Sustainable Abstraction Limits in Confined Aquifers: Example from Deep Confined Aquifers in the Bordeaux Region, France -- Chapter 13. A tool to Determine Annual Ground-Water Allocations in the Tarn-et-Garonne Alluvial Aquifer (France) -- Chapter 14. Conceptual Approaches, Methods and Models used to Assess Extraction Limits in Australia: From Sustainable to Acceptable Yield -- Chapter 15. Case Study: An Integrated Approach to Determining Sustainable Abstraction Limits in Perth’s North West Urban Growth Corridor -- Chapter 16. Using Resource Condition Limits to Define Groundwater Management Objectives in the Barossa Valley, South Australia -- Chapter 17. Reducing Entitlements when Groundwater has been Over-allocated: Policy Issues and Options -- Chapter 18. Developing Substitution Resources as Compensation for Reduced Groundwater Entitlements: The Case of the Poitou Marshes (France) -- Chapter 19. New Approaches for Allocation Reductions and Groundwater Salinity Management in South Australia -- Chpater 20. Reducing Groundwater Entitlements in the Lower Murrumbidgee Groundwater Management Area -- Chapter 21. Development of Groundwater Markets in Australia: Insights from Victoria in the Murray Darling Basin -- Chapter 22. Groundwater Regulation, Compliance and Enforcement: Insights on Regulators, Regulated Actors and Frameworks in New South Wales, Australia -- Chapter 23. Compliance and Enforcement: the Achilles Heel of French Water Policy -- Chapter 24. The Role of Sectoral Policies to Restore Groundwater Balance: The Impact of Agricultural Policies on Irrigation Water Demand in France -- Chapter 25. Groundwater Management Lessons from Chile -- Chapter 26. California’s 2014 Sustainable Groundwater Management Act – From the Back Seat to the Driver Seat in the (Inter)National Groundwater Sustainability Movement -- Chapter 27. Changing from Unrestricted access to Sustainable Abstraction Management Regimes: Lessons Learnt from France and Australia. .
    Abstract: This book describes and analyses the diversity of possible approaches and policy pathways to implement sustainable groundwater development, based on a comparative analysis of numerous quantitative management case studies from France and Australia. This unique book brings together water professionals and academics involved for several decades in groundwater policy making, planning or operational management to reflect on their experience with developing and implementing groundwater management policy. The data and analysis presented accordingly makes a significant contribution to the empirical water management literature by providing novel, real world insights unpublished elsewhere. The originality of the contributions also lies in the different disciplinary perspectives (hydrogeology, economics, planning and social sciences in particular) adopted in many chapters. The book offers a unique comparative analysis of France, Australia and experiences in countries such as Chile and the US to identify similarities, but also fundamental differences, which are analysed and presented as alternative policy options – these differences being mainly related to the role of the state, the community and market mechanisms in groundwater management.
    Type of Medium: Online Resource
    Pages: XVII, 562 p. 149 illus., 143 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030327668
    Series Statement: Global Issues in Water Policy, 24
    DDC: 551
    Language: English
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  • 16
    Online Resource
    Online Resource
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Keywords: Geology. ; Sedimentology. ; Oceanography. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Geology. ; Sedimentology. ; Ocean Sciences. ; Fossil Fuel.
    Description / Table of Contents: Regional tectonic setting and prototype basin evolution -- Characteristics and evolution of Lithofacies Paleogeography -- Major source rocks and distribution -- Reservoir type and origin -- Regional cap rock and hydrocarbon preservation -- Reservoir type and spatial distribution.
    Abstract: This book systematically introduces the petroleum geological characteristics and exploration theory of marine strata in China. On the basis of four major basins, 14 typical cases have been studied in which 13 cases are from conventional oil and gas fields and 1 case is from shale gas field, along with their hydrocarbon generation, migration, accumulation, and distribution characteristics. The book provides a reference for geologists around the globe to understand the exploration history, methods and advances in marine strata oil and gas exploration in China.
    Type of Medium: Online Resource
    Pages: XXII, 570 p. 322 illus., 295 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783662611470
    DDC: 551
    Language: English
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  • 17
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Mineralogy. ; Power resources. ; Geology. ; Mineralogy. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Geology of Suriname -- Chapter 3. A Brief History of Exploration Work -- Chapter 4. Modeling Potential: Minimal Economic Resource Parameters -- Chapter 5. Gold -- Chapter 6. Bauxite -- Chapter 7. Base metals -- Chapter 8. Other Metallic Minerals -- Chapter 9. Critical Raw Materials -- Chapter 10. Other Minerals -- Chapter 11. Looking ahead.
    Abstract: This book summarizes the exploration history and provides a framework for assessing the economic potential of the country’s minerals by defining minimal deposit parameters for the various commodities present. Suriname was explored extensively for mineral occurrences in the course of the previous century, indicating the presence of a range of commodities. The country mined and processed bauxite for a century (until 2016), and has an even longer history of small-scale alluvial gold mining; it is currently home to two major gold producers. However, exploration activities have been limited during the past 4 decades as most parts of Suriname’s interior are difficult to access, making geological fieldwork both difficult and expensive. Further, the markets and prices have changed in the interim, which calls for a fresh look at the historic data. .
    Type of Medium: Online Resource
    Pages: XV, 90 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030402686
    Series Statement: SpringerBriefs in Earth Sciences,
    DDC: 551
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Mineralogy. ; Conservation biology. ; Ecology . ; Geotechnical engineering. ; Geology. ; Mineralogy. ; Conservation Biology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: 1.Slate in architecture -- 2.The origin of slate -- 3.Methodology and standards -- 4.Properties of slate -- 5.Weathering of slate -- 6.Mining of slate and production -- 7.Slate deposits.
    Abstract: This book offers a comprehensive review devoted exclusively to slate as dimension stone. Beginning with a description of the slate as dimension stone, the book describes the origin of slate and related geological phenomena. It thoroughly explains key data acquisition methods and techniques, which are accompanied by extensive data. In turn, slate standards are introduced and compared with regard to their importance for product quality. The book covers in detail the specific petrographical, fabric, strength, physical properties and weathering behaviour of slates. The chapter on mining and production provides an overview of the different forms of exploitation and related geotechnical aspects, together with production and workflow design, from the beginning to the final product. The second part comprises a thorough description of worldwide slate deposits and their geology, properties and appearance as well as a brief introduction of the history. Given its scope and accessible format, the book represents an essential guide for scientists, engineers, and professionals in geology, conservation science, architecture, and mining, as well as readers who are active in the slate industry.
    Type of Medium: Online Resource
    Pages: XI, 492 p. 305 illus., 283 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030356675
    Series Statement: Springer Mineralogy,
    DDC: 551
    Language: English
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  • 19
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geology. ; Geophysics. ; Mineralogy. ; Geology. ; Geophysics. ; Mineralogy.
    Description / Table of Contents: Introduction -- Tectonic Domains and Tectonic Units in Asian Continent -- The Tectonic Evolution of Asian Continental Lithosphere -- Tectono-Metallogenesis in Asian Continent.
    Abstract: The purpose of this book is to provide a review of tectonic outlines of the Asian continent, metallogenesis rules of 242 large deposits or fields in 67 tectonic units of 6 tectonic domains in the Asia, and guidelines for the mining companies to effectively prospect the large deposits in the Asia in future. The main contents include the tectonic evolution of every tectonic unit in Asia at different geological periods, the mechanism of growth and intraplate deformation of the Asian continental lithosphere, the lithospheric types of the Asian continent, and relationship between tectonic evolution and mineralization process in the Asian continent. .
    Type of Medium: Online Resource
    Pages: XI, 319 p. 201 illus., 190 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811530326
    DDC: 551
    Language: English
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  • 20
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Climatology. ; Computer simulation. ; Natural Hazards. ; Environmental Social Sciences. ; Climate Sciences. ; Computer Modelling.
    Description / Table of Contents: Pitfall of Disaster Information: From the Perspective of Double-bind Theory -- Single-person Drill for Tsunami Evacuation and Disaster Education -- Using Computer Simulation for Effective Tsunami Risk Communication -- Gaming Approach to Disaster Risk Communication: Development and application of "Crossroad Game" -- Local Weather Information: Collaboration between Weather Forecasters and Information Users -- Disaster Education based on Legitimate Peripheral Participation Theory: A New Model of Disaster Science Communication -- Do Developed Countries Learn DRR from Developing Countries? -- Communicating Warnings in an Immanent Time Frame: Earthquake Early Warning and Short-Term Forecasting in Japan and the US.
    Abstract: This book provides a unique blend of integrated disaster risk communication research conducted by authors with diverse backgrounds, including social psychology, sociology, civil engineering, informatics, and meteorology. It reports on the latest advances in collaborative and participatory action research on community-based disaster management from the frontline in Japan, Nepal, China and the USA. In addition, it employs and integrate a broad range of methodologies, including mathematical analyses, computer simulations, questionnaire surveys, gaming approaches, and participatory observation. Each chapter deals with disaster risk communication initiatives to address various hazards, such as earthquakes, tsunamis, floods and landslides, which are uniquely integrated from a social psychological perspective.
    Type of Medium: Online Resource
    Pages: XXXV, 153 p. 35 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811323188
    Series Statement: Integrated Disaster Risk Management,
    DDC: 551
    Language: English
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  • 21
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geomorphology. ; Physical geography. ; Geochemistry. ; Geography. ; Geology. ; Geomorphology. ; Earth System Sciences. ; Geochemistry. ; Regional Geography.
    Description / Table of Contents: Chapter1. Introduction -- Chapter2. Evolving Early Earth: Insights from Peninsular India -- Chapter3. Tracking India within Precambrian supercontinent cycles -- Chapter4. Proterozoic Sedimentary basins of India -- Chapter5. Oxygenation of early atmosphere and potential stratigraphic records from India -- Chapter6. Early life from the Proterozoic sedimentary basins of India -- Chapter7. Geodynamics of Gondwanaland -- Chapter8. Cretaceous Volcanism in Peninsular India: Rajmahal_Sylhet, Deccan Traps -- Chapter9. Phanerozoic Mass Extinctions and Indian Stratigraphic Records -- Chapter10. Geological Evolution of the Himalayan Mountains -- Chapter11. Cenozoic Himalayan foreland basin: an overview and regional perspective of the evolving sedimentary succession -- Chapter12. Active tectonics of Himalayan frontal fault zone in the Sub Himalaya -- Chapter13. Late Quaternary evolution and morphostratigraphic development of the Ganga Plains -- Chapter14. Evolution and development of the Indian Monsoon -- Chapter15. Climate Change over the Indian sub-continent.
    Abstract: This book provides insights on new geological, tectonic, and climatic developments in India through a time progression from the Archean to the Anthropocene that are captured via authoritative entries from experts in earth sciences. This volume aims to bring graduate students and researchers up to date on the geodynamic evolution of the Indian Plate; concepts that have so far resulted in a rather uneven treatment of the subject at different institutions. The book is divided into 4 sections and includes perspectives such as the formation and evolution of the Indian crust in comparison to its neighbors such as Antarctica, Africa and Australia; the evolution of Precambrian cratons and sedimentary basins of India; and a summary account of early life reported in the Indian stratigraphic record. Readers will also discover the key recent research into the neotectonics, tectonic geomorphology, and paleoseismology of the Himalayan Front. Researchers and students in geology, earth sciences, sedimentology, paleobiology and geography will find this book appealing.
    Type of Medium: Online Resource
    Pages: VIII, 574 p. 173 illus., 139 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030159894
    Series Statement: Springer Geology,
    DDC: 551
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Water. ; Hydrology. ; Pollution. ; Environment. ; Sustainability. ; Geology. ; Water. ; Pollution. ; Environmental Sciences. ; Sustainability.
    Description / Table of Contents: 1. Preface -- 2. Part I - Evolution of water management in Italy -- 3. Chapter 1. Italy’s outline M. Benedini -- 4. Chapter 2. Paradigm changes in water resources development G. Rossi -- 5. Chapter 3. Water Legislation: main innovation principles on water resources uses, pollution control and flood risk mitigation, G. Rossi -- 6. Chapter 4. Institutional framework of water governance: planning, service management and soil defense) G. Rossi -- 7. Part II - Water resources and water demands -- 8. Chapter 5. Conventional water resources (Surface and ground water resources) G. Rossi, M. Benedini -- 9. Chapter 6. Unconventional water resources (desalinated waters and treated wastewater reuse) G. Rossi, G. Cirelli -- 10. Chapter 7. Assessment of water requirements (domestic and urban uses; agricultural uses; industrial uses, navigation…) M. Benedini, R. Drusiani -- 11. Part III - Problems -- 12. Chapter 8. Management of municipal water services M. Di Natale, G. Rossi -- 13. Chapter 9. Water pollution control M. Benedini -- 14. Chapter 10. Water and electric power G. Ruggeri, M. Benedini -- 15. Chapter 11. Ecological in-stream flows (or water and environment) S. Alecci, G Rossi -- 16. Part IV – Challenges -- 17. Chapter 12. Mitigation of flood risk G. Rossi -- 18. Chapter 13. Coping with droughts G. Rossi -- 19. Chapter 14. Virtual water F. Laio, S. Tamea, M. Tuminetti -- 20. Chapter 15. Adaptations strategies to climate change in water resources D. Peres -- 21. Part V – Conclusions -- 22. Chapter 16. The future of water management in Italy M. Benedini, G. Rossi. .
    Abstract: This book offers a comprehensive framework of the current state of water resources in Italy and of the main stages of the evolutionary way in the last decades for achieving an integrated, sustainable and equitable water resources management. The main paradigms of water resources development are identified as: i) engineering and economic approach to water resources exploitation, ii) focus on pollution control and water-excess management, iii) a comprehensive approach toward a sustainable and equitable distribution of resources and effective risk reduction of water-related disasters. After a section devoted to the analysis of some historic stages in the legislation framework and the governance of water and soil, with particular reference to planning, design, building and operation of water systems, two sections deal with the estimation of water resources availability on national territory and estimation of water demands in municipal, agricultural, industrial, ecosystem sectors. The complex problems that the Italian society has to solve in the water field and the main challenges of a changing world are discussed in the fourth section of the volume. The book will not only be useful for water professionals, but also for citizen who like to discern the key factors which delay the recognition of water as a resource for life. The description of the problems and adopted solutions could also serve as a guideline for similar situations encountered in other countries, improving the preparation of the responsible people.
    Type of Medium: Online Resource
    Pages: XVII, 365 p. 97 illus., 80 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030364601
    Series Statement: World Water Resources, 5
    DDC: 551
    Language: English
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  • 23
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Pollution. ; Water. ; Hydrology. ; Physical geography. ; Geology. ; Pollution. ; Water. ; Earth System Sciences.
    Description / Table of Contents: 1. Introduction -- 2. Urban hydrology -- 3. Research of rainwater infiltration -- 4. Percolation facilities -- 5. Legislation – technical standards -- 6. Results of research- Design of percolation facility -- 7. Recommendations.
    Abstract: The book presents a comprehensive study of the percolation of water from surface runoff with a focus on the retention capacity and intensity of precipitation. Discussing the state of the art in scientific knowledge and solutions for the infiltration of water from surface runoff, the book addresses a wide variety of rainwater management issues, from precipitation, surface runoff and water infiltration, to impact on the drainage system. Although modern urban hydrology has improved the management of rainwater runoff for flood protection, public health, and environmental protection, current methods of drainage in urban areas mean that there is a continued threat to the regime of water flow and water resources. In this context, the book presents a new approach to rainwater management based on a unique fusion of hydrology, hydrogeology, urban engineering, and water management. It also includes research findings that are helpful in developing recommendations and technical guidelines for the use of infiltration systems in urban areas.
    Type of Medium: Online Resource
    Pages: XIII, 141 p. 94 illus., 82 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030346980
    Series Statement: Water Science and Technology Library, 89
    DDC: 551
    Language: English
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  • 24
    Keywords: Geology. ; Mineralogy. ; Paleontology . ; Geology. ; Mineralogy. ; Paleontology.
    Abstract: This volume provides an overview and tour (with many interesting stops along the way) of Devonian and Ordovician intraplate magmatism and associated sedimentary rocks and tectonics in the regions of Kuznetsk Alatau, Minusinsk Basin and Khakassia in western Siberia. All chapters were written by experts, many of which have been studying these regions for decades. The first book to present and review this information in English for an international audience, it includes both overviews of the magmatic and associated sedimentary history, and selected key field sites, which are described in detail.
    Type of Medium: Online Resource
    Pages: X, 232 p. 140 illus., 124 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030295592
    Series Statement: GeoGuide,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Sedimentology. ; Geophysics. ; Paleontology . ; Geology. ; Sedimentology. ; Geophysics. ; Paleontology.
    Description / Table of Contents: Part I: Sedimentary basins, petroleum resources and reservoirs in the Arabian plate High-resolution stratigraphic architectures, facies anatomies of the Lower Cretaceous Biyadh and Shu’aiba formations, and their implications on platform evolution and global correlation -- The Lower Cretaceous Chouf Sandstone of Lebanon: a regional reservoir level in the Levant? -- Seismic tectono-stratigraphy and hydrocarbon implications of lowstand deep marine Oligo-Miocene siliciclastic reservoirs in the Northern Levant Basin -- Source-to-sink analysis of the Plio-Pleistocene deposits in the Suez rift (Egypt). Part II: Geophysics and structural styles The Southern Atlas front in Tunisia: Regional-scale geometry and structural evolution. U-Pb zircon geochronology and geochemistry of some plutonic rocks from the Afif terrane of Saudi Arabia, Arabian Shield: implications for crustal evolution -- Aeromagnetic data investigation of Al-Shamiyya area, north east of Makkah quadrangle, Saudi Arabia. Part III: Hydrology, hydrogeology and water resources Groundwater contamination of Wadi Haliy area, Southwestern Arabian Shield, Saudi Arabia -- Analysis of rainfall, missing data, frequency and PMP in Al-Madinah area, Western Saudi Arabia -- Hydrochemical assessment of groundwater within the Lower Wadi Ranyah, Western Saudi Arabia using multivariate statistical technique.
    Abstract: This book focuses on the evolution of sedimentary basins of the Arabian Plate and its surroundings. Because these sedimentary basins developed in various tectonic settings, from extensional or transtensional to flexural, transpressional or compressional, their sedimentary sequences provide unique records of the regional geology. Georesources of the Arabian Plate are also described here, including petroleum potential, reservoirs, water resources, fresh water and deep saline aquifers, as well as materials and ore deposits. The book is made by a set of papers authored by geoscientists working in both academia and industry. Numerous chapters describe some regional important geologic features and selected sedimentary basins from the Middle East, North Africa and the Arabian Peninsula domains. Other chapters focus on georesources. A particular focus is given to the geology of Saudi Arabia. This book is an important contribution to the geology of the Arabian Peninsula and its surroundings. In view of the strategic and economic importance of the regional geology and georesources of the Arabian Plate and Surroundings, this volume will constitute an important reference for a wide range of geoscientists interested in the geology of this region, especially those active in petroleum geosciences and related industry. Ultimately, readers will discover important thematic maps in this book.
    Type of Medium: Online Resource
    Pages: VIII, 257 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030218744
    Series Statement: Regional Geology Reviews,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Water. ; Hydrology. ; Engineering mathematics. ; Engineering Data processing. ; Computer simulation. ; Geology. ; Water. ; Mathematical and Computational Engineering Applications. ; Computer Modelling.
    Description / Table of Contents: 1.Introduction -- 2.Hydrology, Hydraulics and Water Resources Engineering -- 3.Science and Art of Water Resources Modeling -- 4.Surface and Groundwater Modeling for Water Utilization -- 5.Reservoir Planning and Operations Studies with Optimization-Simulation Models -- 6.Reservoir Sedimentation Studies -- 7.Hydrodynamic and Water Quality Modeling of Bays and Lake -- 8. Pipe Network Distribution Modeling with Optimization -- 9.Climate Change Studies for Reliability of a Reservoir and Groundwater Water Supply -- 10.Environmental Impact Assessment Studies -- 11.Specialized Modeling Studies -- 12.Imperatives and Needs to Improvement of Water Resources Modeling and Applications in the Philippines.
    Abstract: This book presents a number of modeling studies of various water resources systems in the humid tropics and the typical short, steep mountain-to-coast systems in the archipelagic setting of the Philippines. Covering natural and rural systems, urban watersheds and built systems, such as reservoirs and flood control systems, it discusses modeling studies based on pure simulation and combined optimization-simulation. The book offers insights into real-world water resources modeling, and as such is a valuable resource for academics and practitioners in the Philippines, as well as those in other Asian regions with similar water resources systems, and similar issues, problems and concerns.
    Type of Medium: Online Resource
    Pages: XXXIX, 403 p. 233 illus., 210 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030254018
    Series Statement: World Water Resources, 4
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Physical geography. ; Conservation biology. ; Ecology . ; Archaeology. ; Paleontology . ; Environmental management. ; Geology. ; Physical Geography. ; Conservation Biology. ; Archaeology. ; Paleontology. ; Environmental Management.
    Description / Table of Contents: Introduction -- 200 years of karst research in the Lagoa Santa area -- Geology of the Lagoa Santa Karst -- The vegetation of the karst region -- Fauna of the Lagoa Santa Karst -- Hydrological behaviour of karst lakes -- Karst soils and their relationship to geomorphology -- Karst landforms -- Karst groundwater routes and dynamics -- Speleogenesis in the Lagoa Santa Karst.
    Abstract: This book discusses the Lagoa Santa Karst, which has been internationally known since the pioneering studies of the Danish naturalist Peter Lund in the early 1800s. It covers the speleogenesis, geology, vegetation, fauna, hydrogeology, geomorphology, and anthropogenic use of the Lagoa Santa Karst and is the first English-language book on this major karst area. The area, which has been at the heart of the debate on the origin and age of human colonization in the Americas, is characterized by a classical and scenic karst landscape with limestone cliffs, karst lakes and karst plains, in addition to numerous solution dolines. More than 1,000 caves have been documented in the area, many with significant archeological and paleontological value. Despite its great importance, the Lagoa Santa Karst faces severe environmental threats due to limestone mining and the expansion of the metropolis of Belo Horizonte and its surrounding towns. The growing recognition of the area’s remarkable significance has led to increasing concern, and a number of protected areas have now been established, improving the conservation status of this landmark karst area.
    Type of Medium: Online Resource
    Pages: X, 330 p. 204 illus., 178 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030359409
    Series Statement: Cave and Karst Systems of the World,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geology.
    Description / Table of Contents: 1. Introduction – History of coal mining in Limburg, and adjacent areas -- 2. The Origin and Classification of Coal – Coalification, macerals, nomenclature of types of coal -- 3. Limburg and adjacent areas in the Carboniferous – Paleogeography, plate tectonics, paleoclimate, position with respect to the equator, the London Brabant Massif and its relation to the coal deposits -- 4. Later burial. Present depth of the coal layers -- 5. Tectonics – uplift and crust extension, the Roergraben, active faults, inactive faults.
    Abstract: This book offers an up-to-date overview of the coal deposits of South Limburg (Netherlands), the Aachen area (Germany), and the Campine area (Belgium). Although the amount of available literature on these coal deposits is quite vast, the majority of the texts date back to the mid-twentieth century, and most publications focus more on the stratigraphy of the coal layers and the rank of the coal. Moreover, the concept of continental drift is largely ignored in these publications. In addition to providing updated information, this book also discusses coal mining in these regions; the formation and petrography of coal; and the geological evolution of Western Europe/the Netherlands, Germany and Belgium. In order to explain the tropical nature of the flora in the Carboniferous period, paleogeographic aspects are also taken into account. .
    Type of Medium: Online Resource
    Pages: XII, 78 p. 49 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030182861
    Series Statement: SpringerBriefs in Earth Sciences,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Pollution. ; Sustainability. ; Environment. ; Geology. ; Pollution. ; Sustainability. ; Environmental Sciences.
    Description / Table of Contents: Introduction to Anthropogenic Aquifer Recharge -- Hydrogeology Basics – Aquifer Types and Hydraulics -- Vadose Zone Hydrology Basics -- Groundwater Recharge and Aquifer Water Budgets -- Geochemistry and Managed Aquifer Recharge Basics -- Anthropogenic Aquifer Recharge and Water Quality -- Contaminant Attenuation and Natural Aquifer Treatment -- MAR Project Implementation -- MAR Hydrogeological and Hydrochemistry Evaluation Techniques -- Vadose Zone Testing Techniques Clogging -- Pretreatment.-ASR and Aquifer Recharge Using Wells -- Groundwater Banking -- Surface-Spreading Systems – Infiltration Basins -- Surface-Spreading Systems (Non-Basin) -- Vadose Zone Infiltration Systems -- Recharge and Recovery Treatment Systems -- Soil-Aquifer Treatment -- Riverbank Filtration -- Saline-Water Intrusion Management -- Wastewater MAR and Indirect Potable Reuse -- Low Impact Development and Rainwater Harvesting -- Unmanaged and Unintentional Recharge.
    Abstract: The book is an overview of the diversity of anthropogenic aquifer recharge (AAR) techniques that use aquifers to store and treat water. It focusses on the processes and the hydrogeological and geochemical factors that affect their performance. This book is written from an applied perspective with a focus of taking advantage of global historical experiences, both positive and negative, as a guide to future implementation. Most AAR techniques are now mature technologies in that they have been employed for some time, their scientific background is well understood, and their initial operational challenges and associated solutions have been identified. However, opportunities exist for improved implementation and some recently employed and potential future innovations are presented. AAR which includes managed aquifer recharge (MAR) is a very important area of water resources management and there is no recent books that specifically and comprehensively addresses the subject. .
    Type of Medium: Online Resource
    Pages: XXV, 861 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030110840
    Series Statement: Springer Hydrogeology,
    DDC: 551
    Language: English
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  • 30
    Keywords: Natural disasters. ; Public health. ; Sustainability. ; Natural Hazards. ; Public Health. ; Sustainability.
    Description / Table of Contents: Introduction -- Overview of H-EDRM and health issues in DRR: Practices and challenges -- Public health prevention hierarchy in disaster context -- Key public health challenges for H-EDRM in the twenty-first century: Demographic and epidemiological transitions -- Evidence gaps in bottom-up resilience building of H-EDRM in Asia -- H-EDRM in international policy agenda I: Sendai Framework for Disaster Risk Reduction 2015–2030 -- H-EDRM in international policy agenda III: Paris climate agreement -- H-EDRM in international policy agenda IV: 2030 Sustainable Development Goals and New Urban Agenda (Habitat III) -- Health issues and DRR in India: Some reflections -- Health issues and disaster risk reduction perspectives in China -- Health emergencies and DRR in Pakistan: examples and achievements -- Bangladesh public health issues and implications to flood risk reduction -- Epi-Nurse: health emergency perspectives in Nepal -- Health emergency and public involvement in Philippines -- Smart water solutions for health emergency in he delta region of Bengal -- Community networking for healthcare in case of disaster: Examples from small and medium sized cities in Japan -- Future perspectives of H-EDRM and risk reduction in Asia. .
    Abstract: This book presents the health emergency and disaster risk management (H-EDRM) research landscape, with examples from Asia. In recent years, the intersection of health and disaster risk reduction (DRR) has emerged as an important interdisciplinary field. In several landmark UN agreements adopted in 2015–2016, including the Sendai Framework for Disaster Risk Reduction 2015–2030, the 2030 Sustainable Development Goals (SDGs), the Paris climate agreement, and the New Urban Agenda (Habitat III), health is acknowledged as an inevitable outcome and a natural goal of disaster risk reduction, and the cross-over of the two fields is essential for the successful implementation of the Sendai Framework. H-EDRM has emerged as an umbrella field that encompasses emergency and disaster medicine, DRR, humanitarian response, community health resilience, and health system resilience. However, this fragmented, nascent field has yet to be developed into a coherent discipline. Key challenges include redundant research, lack of a strategic research agenda, limited development of multisectoral and interdisciplinary approaches, deficiencies in the science–policy–practice nexus, absence of standardized terminology, and insufficient coordination among stakeholders. This book provides a timely and invaluable resource for undergraduate and postgraduate students, researchers, scholars, and frontline practitioners as well as policymakers from across the component domains of H-EDRM.
    Type of Medium: Online Resource
    Pages: XVI, 343 p. 49 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811509247
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geophysics. ; Environment. ; Geology. ; Geophysics. ; Environmental Sciences.
    Description / Table of Contents: Stress-Strain State of Rocks -- Deformation and Fracture of Rocks In The Presence of Filtration -- Mechanical and Mathematical, and Experimental Modeling of Oil and Gas Well Stability -- Equipment For Studying Deformation and Strength Properties of Rocks In Triaxial Loading -- Loading Programs For Rock Specimens On Triaxial Independent Loading Test System (Tilts) -- Dependence of Permeability On Stress State -- Influence of Filtration On Stress-Strain State and Rock Fracture In The Well Vicinity -- Results of Tests of Rock Specimens By Using Tilts -- Mathematical Modeling of Mechanical and Filtration Processes In Near-Wellbore Zone -- Directional Unloading Method - A New Approach To Enhancing of Oil and Gas Well Productivity.
    Abstract: The book presents an integrated approach to studying the geomechanical processes occurring in oil and gas-bearing formations during their development. It discusses the choice of a model that takes into account the basic properties of rocks; experiments to find model parameters; numerical modeling; and direct physical modeling of deformation and filtration processes in reservoir and host rocks. Taking into account features of rock behavior, such as anisotropy of the mechanical properties of rocks during elastoplastic deformation; dependence of permeability on the total stress tensor; the contribution of the filtration flow to the formation stress state; and the influence of tangential as well as normal stresses on the transition to inelastic deformation, it demonstrates how the presented approach allows the practical problems of increasing the productivity of wells, oil recovery, and ensuring the stability of wellbores to be solved. The book is intended for specialists, including geoengineers working in the oil and gas sector, teachers, graduate students and students, as well as all those interested in scientific and technological developments to meet the enormous demand for raw materials and energy. .
    Type of Medium: Online Resource
    Pages: XVI, 166 p. 140 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030266080
    Series Statement: Advances in Oil and Gas Exploration & Production,
    DDC: 551
    Language: English
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  • 32
    Keywords: Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Environmental chemistry. ; Environmental management. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Water. ; Freshwater and Marine Ecology. ; Environmental Chemistry. ; Environmental Management. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Section I Overview -- 1 Introduction to the volume -- 2 Deep-water oil and gas production in the Gulf of Mexico, and related global trends -- 3 Spilled oil composition and the natural carbon cycle: The true drivers of environmental fate and effects of oil spills -- Section II Geological, Chemical, Ecological and Physical Oceanographic Settings and Baselines for Deep Oil Spills in the Gulf of Mexico -- 4 An overview of the geologic origins of hydrocarbons and production trends in the Gulf of Mexico -- 5 Gulf of Mexico (GoM) bottom sediments and depositional processes: A baseline for future oil spills -- 6 Benthic faunal baselines in the Gulf of Mexico: A precursor to evaluate future impacts -- 7 Linking abiotic variables with macrofaunal and meiofaunal abundance and community -- 8 The asphalt ecosystem of the southern Gulf of Mexico: abyssal habitats across space and time -- 9 Geochemical and faunal characterization in the sediments off the Cuban north and northwest coast -- 10 Mapping isotopic and dissolved organic matter baselines in waters and sediments of Gulf of Mexico -- 11 Toward a predictive understanding of the benthic microbial community response to oiling on the northern Gulf of Mexico coast -- 12 Combining isoscapes with tissue-specific isotope records to re-create the geographic histories of fish -- 13 The utility of stable and radio isotopes in fish tissues as biogeochemical tracers of marine oil spill food web effects -- 14 Modernizing protocols for aquatic toxicity testing of oil and dispersant -- 15 Polycyclic aromatic hydrocarbon baselines in Gulf of Mexico fishes -- 16 Case Study: Using a combined laboratory, field, and modeling approach to assess oil spill impacts -- Section III Simulations of Future Deep Spills -- 17 Testing the effect of MOSSFA (Marine Oil Snow Sedimentation and Flocculent Accumulation) events in benthic microcosms -- 18 Physical processes influencing the sedimentation and lateral transport of MOSSFA in the NE Gulf of Mexico -- 19 Simulating deep oil spills beyond the Gulf of Mexico -- Section IV Comparisons of likely impacts from simulated spills -- 20 Comparison of the spatial extent, impacts to shorelines, and ecosystem and 4-dimensional characteristics of simulated oil spills -- 21 A predictive strategy for mapping locations where future MOSSFA events are expected -- 22 Connectivity of Gulf of Mexico continental shelf fish populations and implications of simulated oil spills -- 23 Evaluating the effectiveness of fishery closures for deep oil spills using a 4-dimensional model -- 24 As Gulf oil extraction goes deeper, who is at risk? Community structure, distribution, and connectivity of the deep-pelagic fauna -- 25 Evaluating impacts of deep oil spills on oceanic marine mammals -- 26 Comparative environmental sensitivity of offshore Gulf of Mexico waters potentially impacted by ultra-deep oil well blowouts -- Section V Preparing for and Responding to the Next Deepwater Spill -- 27 Preparing for the inevitable: ecological and indigenous community impacts of oil spill-related mortality in the United States Arctic marine ecosystem -- 28 Summary of contemporary research on use of chemical dispersants for deep sea oil spills -- 29 Perspectives on research, technology, policy and human resources for improved management of ultra-deep oil and gas resources and responses to oil spills -- Index.
    Abstract: It has often been said that generals prepare for the next war by re-fighting the last. The Deepwater Horizon (DWH) oil spill was unlike any previous – an underwater well blowout 1,500 meters deep. Much has been learned in the wake of DWH and these lessons should in turn be applied to both similar oil spill scenarios and those arising from “frontier” explorations by the marine oil industry. The next deep oil well blowout may be at 3,000 meters or even deeper. This volume summarizes regional (Gulf of Mexico) and global megatrends in marine oil exploration and production. Research in a number of key areas including the behavior of oil and gas under extreme pressure, impacts on biological resources of the deep sea, and the fate of oil and gas released in spills is synthesized. A number of deep oil spills are simulated with detailed computer models, and the likely effects of the spills and potential mitigation measures used to combat them are compared. Recommended changes in policies governing marine oil exploration and development are proposed, as well as additional research to close critical and emerging knowledge gaps. This volume synthesizes state-of-the-art research in deep oil spill behavior and response. It is thus relevant for government and industry oil spill responders, policy formulators and implementers, and academics and students desiring an in-depth and balanced overview of key issues and uncertainties surrounding the quest for deep oil and potential impacts on the environment.
    Type of Medium: Online Resource
    Pages: XII, 542 p. 167 illus., 138 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030129637
    DDC: 551.48
    Language: English
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    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Medical genetics. ; Pharmacology. ; Biomedical Research. ; Medical Genetics.
    Description / Table of Contents: Chapter 1. Introduction and Principles of Pharmacogenomics and Precision medicine -- Chapter 2. Pharmacogenomics in Cardiovascular Diseases -- Chapter 3. Pharmacogenomics of Antitumor Chemotherapeutic Agents -- Chapter 4. Pharmacogenomics of Antitumor Targeted Agent and Immunotherapy -- Chapter 5. Pharmacogenomics of Immunosuppressant -- Chapter 6. Pharmacogenomics of Psychiatric drugs -- Chapter 7. Pharmacogenomics of Anti-Infective Agents -- Chapter 8. Pharmacogenomics of Antithrombotic drugs -- Chapter 9. Pharmacogenomics in Therapeutic Drug Monitoring -- Chapter 10. Pharmacomicrobiomics -- Chapter 11. Genotyping technology in Pharmacogenomics -- Chapter 12. The Ethical, Legal and Regulatory Issues Associated with Pharmacogenomics -- Chapter 13. Cost-effectiveness of pharmacogenetic-guided treatment -- Chapter 14. Application of pharmacogenomics in drug discovery and development -- Chapter 15. Barriers and Solutions in Clinical Implementation of Pharmacogenomics for Personalized Precision Medicine.
    Abstract: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
    Type of Medium: Online Resource
    Pages: VIII, 289 p. 33 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811538957
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Medical microbiology. ; Dermatology. ; Orthopedic surgery. ; Pharmacology. ; Medical Microbiology. ; Dermatology. ; Surgical Orthopedics.
    Description / Table of Contents: Part 1-Nanotechnology in Skin Infections -- Atopic dermatitis and current trends in pharmacological treatment - a nanoparticulate approach -- Acne vulgaris - recent trends on pharmacological and nanotechnological approaches in therapeutics -- Nitric oxide nanoparticles on skin infections: Current State and Future Prospects -- Metal Nanoparticles Based Antibacterial Nanocomposites for Skin Infections -- Combination therapy using metal nanoparticles for skin infection -- Applications of nanometals in cutaneous infections -- Antifungal nanotherapy: a novel approach to combat superficial fungal infections -- Biocompatible polymers for skin Nanomedicines -- Part 2-Nanotechnology on Soft-Tissue Infections -- Nanotechnological approach to manage diabetic foot ulcer -- Metal nanoparticles in wound infections -- Advances in nanomedicine for burn wound infection treatment -- Applications of chitosan in formulation of novel antibacterial agents and wound dressings -- Polymeric nanocomposites for skin and soft tissues -- Nanoformulations of polyphenols for the treatment of soft tissues infections -- Cutting Edge Nanotechnologies for Targeting Liver Disorders -- NanoCurcumin compounds formulations: Perspectives in skin and soft tissues infections -- Nanobiotechnology strategies for the treatment tegumentary and visceral leishmaniases, and emergence resistance -- Part 3-Nanotechnology in Bone Infections -- Artificial Scaffolds for Bone Tissue Engineering -- The bone biology and the nanotechnology for bone infections and bone engineering -- Part 4-Nanotechnology and Toxicity -- Genotoxicity studies of Silver Nanoparticles in in vivo and in vitro models.
    Abstract: The main goal of the present book is to deal with the role of nanobiotechnology in skin, soft tissue and bone infections since it is difficult to treat the infections due to the development of resistance in them against existing antibiotics. The present interdisciplinary book is very useful for a diverse group of readers including nanotechnologists, medical microbiologists, dermatologists, osteologists, biotechnologists, bioengineers. Nanotechnology in Skin, Soft-Tissue, and Bone Infections is divided into four sections: Section I- includes role of nanotechnology in skin infections such as atopic dermatitis, and nanomaterials for combating infections caused by bacteria and fungi. Section II- incorporates how nanotechnology can be used for soft-tissue infections such as diabetic foot ulcer and other wound infections; Section III- discusses about the nanomaterials in artificial scaffolds bone engineering and bone infections caused by bacteria and fungi; and also about the toxicity issues generated by the nanomaterials in general and nanoparticles in particular. The readers will be immensely enriched by the knowledge of new and emerging nanobiotechnologies in a variety of platforms.
    Type of Medium: Online Resource
    Pages: XI, 285 p. 39 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030351472
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Cancer. ; Clinical biochemistry. ; Pharmacology. ; Cancer Biology. ; Medical Biochemistry.
    Description / Table of Contents: Part 1. New Roles for Sphingolipid Signaling and Cell Function -- 1. Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma -- 2. Exploring the Therapeutic Landscape of Sphingomyelinases -- 3. Sphingosine kinases as druggable targets -- Part 2. Phospholipase D and Mitogen Phosphatidic Acid in Human Disease -- 4. Prospects for PLD inhibition in cancer and thrombotic disease -- 5. Phospholipase D and the Mitogen Phosphatidic Acid in Human Disease: Inhibitors of PLD at the Crossroads of Phospholipid Biology and Cancer -- 6. Role of Phospholipase D-Derived Phosphatidic Acid in Regulated Exocytosis and Neurological Disease -- Part 3. Lipid Kinases and Novel Regulatory Pathways -- 7. Diacylglycerol Kinase Malfunction in Human Disease and the Search for Specific Inhibitors -- 8. Functions of Nuclear Polyphosphoinositides -- Part 4. Bioactive Lipids in Health and Disease -- 9. Platelet-Activating Factor as an Effector for Environmental Stressors -- 10. Phospholipase D and Choline Metabolism -- Part 5- Lipids and Membrane Microdomains -- 11. Regulation of Inositol Biosynthesis: Balancing Health and Pathophysiology -- 12. Lipids and Membrane Microdomains: The Glycerolipid and Alkylphosphocholine Class of Cancer Chemotherapeutic Drugs -- Part 6. Nuclear Trafficking of Lipids -- 13. Inositide-Dependent Nuclear Signalling in Health and Disease -- 14. Lipids in Exosome Biology.
    Abstract: Lipids are an integral part of cell membrane architecture, are intermediaries in cell metabolism, and are involved in transmitting cell signals from hormones, growth factors and nutrients. A number of lipases and phospholipases, lipid kinases, lipid phosphatases, sphingosine kinases, and their reaction products have been implicated in fundamental cellular processes including cell proliferation, division and migration. These enzymes and their products underlie the molecular mechanisms of numerous human diseases, in particular metabolic disease (diabetes), cancer, neurodegenerative disease and cardiovascular disease. Over the last decade, studies have advanced to the point that a number of inhibitors for these enzymes have been developed to attempt to ameliorate these conditions; some of the inhibitors are currently in human clinical trial. The need for this book is to review the current status of this field and the prospect for the inhibitors to be clinically important. .
    Type of Medium: Online Resource
    Pages: XIV, 336 p. 50 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030336684
    Series Statement: Handbook of Experimental Pharmacology, 259
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Gynecology . ; Environmental health. ; Pharmacology. ; Gynecology. ; Environmental Health.
    Description / Table of Contents: Preface -- Environmental Exposure Measurements and Evaluations -- Prenatal Smoke Exposure and Child Health -- Prenatal Pesticide Exposure and Child Health -- Prenatal Metal Exposure and Child Health -- Prenatal Stress and Child Health -- The Special Vulnerabilities of Child to Environmental Hazards -- Early-life Environmental Influences on Growth -- Early-life Environmental Influences on Neural Development -- Early-life Environmental Influences on Allergic Diseases -- Early-life Social and Economic Adversities on Health -- Endocrine Disrupting Chemical Exposure and Later-onset Diseases -- Paternal Specific Exposure and Child Health -- Molecular Mechanism of Early-life Chemical Exposure Induced Harmful Effects -- Transgenerational Effects on Developmental Origins of Diseases.
    Abstract: This book offers valuable insights into the latest concepts and findings from epidemiologic, clinical and basic studies in the burgeoning area of early-life environmental exposure and diseases. The book is divided into five parts, starting with an overview of environmental exposure measurement and evaluation, followed by a review of the effects of exposure to various substances like tobacco smoke, pesticides and metals as well as stress on offspring’s health. It then discusses the developmental origins of a range of childhood diseases that affect growth, neural development and the immune system, and highlights the importance of longitudinal studies that measure exposure at potentially sensitive time points during childhood. It also provides up-to-date evidence of the intergenerational/transgenerational effects of early-life environmental exposure, especially via genetic and epigenetic pathways. Allowing readers to gain a thorough understanding of the predominating aspects of early-life environmental exposure and diseases, the book also provides a basis for developing environmental and health policies that could have wide and long-term impacts on human health. .
    Type of Medium: Online Resource
    Pages: XVI, 239 p. 22 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811537974
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pharmacovigilance. ; Pharmaceutical chemistry. ; Chemistry, Physical and theoretical. ; Biotechnology. ; Pharmacology. ; Drug Safety and Pharmacovigilance. ; Pharmaceutics. ; Theoretical Chemistry. ; Biotechnology.
    Description / Table of Contents: Introduction -- PART 1: How Drugs are Discovered and Developed in the Pharmaceutical Industry -- Introduction to Drugs and Drug Targets -- Background to chemistry of small and large molecules -- Laying the foundations- Drug discovery from antiquity to the twenty first century -- Part II-The drug development pipeline – discovery to testing in humans -- Drug discovery pipeline overview -- Target discovery -- Medicinal chemistry -- Biotherapeutics -- Screening for hits -- Process chemistry and formulation -- Preclinical development -- Part III-The drug development pipeline – clinical trials to marketing authorisation -- Clinical trials -- Regulatory affairs and marketing approval -- Diagnostics and personalized medicine -- Putting it All Together: a drug development case history -- Part IV- The Global Pharmaceuticals Business -- Commercial aspects of drug development -- Challenges and responses -- Part V - Professional Interactions with the Drug Discovery Industry.-Professional Interactions with the Drug Discovery Industry: Technology Transfer Executives -- Recruitment Executives -- Pharmaceutical translators and Interpreters.
    Abstract: The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the twenty chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators .
    Type of Medium: Online Resource
    Pages: XVII, 402 p. 102 illus., 20 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030578145
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicinal chemistry. ; Polymers. ; Biotechnology. ; Pharmacology. ; Medicinal Chemistry. ; Polymers. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Interpenetrating Polymer Network in Microparticulate Systems: Drug Delivery and Biomedical Application -- Chapter 2. Interpenetrating Polymer Network (IPN) Nanoparticles for Drug Delivery Applications -- Chapter 3. Fabrication Technology of Chitosan-Based IPN: Drug Delivery Application -- Chapter 4. Alginate based Interpenetrating Network Carriers for Biomedical Applications -- Chapter 5. pH Sensed Interpenetrating Polymeric Network: Application in drug delivery -- Chapter 6. IPN Dendrimers in Drug Delivery -- Chapter 7. BioproteinBased IPN Nanoparticles as Potential Vehicles for Anticancer Drug Delivery: Fabrication Technology -- Chapter 8. Semi-IPN systems for drug delivery -- Chapter 9. IPN Systems for Cancer Therapy -- Chapter 10. Semi-interpenetrating networks based on (meth)acrylate, itaconic acid and poly(vinyl pyrrolidone) hydrogels for biomedical applications -- Chapter 11. Biomedical Applications of Interpenetrating Polymer Network Gels -- Chapter 12. Bio-Nanocomposite IPN for Biomedical Application.-.
    Abstract: The book focuses on novel interpenetrating polymer network (IPN)/semi-IPN technologies for drug delivery and biomedical applications. The dynamism of the design and development of interpenetrating network polymers is based on their ability to provide free volume for the easy encapsulation of drugs in the three-dimensional network structure obtained by cross-linking two or more polymer networks. Natural polymer-based IPNs can deliver drugs at a controlled rate over an extended period of time, while novel IPNs ensure better mechanical strength and sustained/ controlled drug-delivery properties. This book presents an overview of the use of this technology to fabricate nanomedicine, hydrogels, nanoparticles, and microparticles, thereby unlocking IPN’s potential in the area of drug delivery and biomedical engineering. It also discusses applications of IPN systems in cancer therapy and tissue engineering, and describes the various IPN systems and their wide usage and applications in drug delivery.
    Type of Medium: Online Resource
    Pages: XII, 337 p. 59 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811502835
    DDC: 615
    Language: English
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  • 39
    Keywords: Pharmacology. ; Human physiology. ; Nanotechnology. ; Biology Technique. ; Pharmacology. ; Human Physiology. ; Nanotechnology. ; Experimental Organisms.
    Description / Table of Contents: Chapter 1. Nanotechnology : Application in biology and medicine -- Chapter 2. Biological activities of nanoparticles and mechanism of action -- Chapter 3. Application of nanoparticles in Drug delivery -- Chapter 4. Antimicrobial activity of metallic nanoparticles using prokaryotic model organisms -- Chapter 5. Modelling nanoparticles parameters for antibacterial activities -- Chapter 6. Saccharomyces cerevisiae as model organism to study biological activities of nanoparticles -- Chapter 7. Investigation of Biological activities of Nanoparticles using Cell Lines -- Chapter 8. Caenorhabditis elegans: a model organism to decipher biological activities of nanoparticles -- Chapter 9. Zebra fish model system to investigate biological activities of nanoparticles -- Chapter 10. Drosophila melanogaster - A model organism to understand biological activities of nanoparticles -- Chapter 11. Understanding the biological activities of nanoparticles using murine models -- Chapter 12. Insecticidal activity nanoparticles and mechanism of action -- Chapter 13. Routes of Exposures and Toxicity of Nanoparticles -- Chapter 14. Toxicological evaluation of nanoparticles using prokaryotic model organisms -- Chapter 15. Evaluation of Toxicity Nanoparticles using Cell lines -- Chapter 16. Saccharomyces cerevisiae : Model organism to evaluate nanoparticles toxicity -- Chapter 17. Caenorhabditis elegans: Evaluation of nanoparticle toxicity -- Chapter 18. Zebra fish: A laboratory model to evaluate Nanoparticle Toxicity -- Chapter 19. Evaluation of toxicity of nanoparticles using Brine Shrimp -- Chapter 20. Drosophila Model to Decipher the Toxicity of Nanoparticles -- Chapter 21. Murine models to understand the toxicity of nanoparticles -- Chapter 22. Challenges and future perspectives of Nanotoxicology.
    Abstract: This book provides a comprehensive overview of state-of-the-art applications of nanotechnology in biology and medicine, as well as model organisms that can help us understand the biological activity and associated toxicity of nanoparticles, and devise strategies to minimize toxicity and enhance therapies. Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics. The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research.
    Type of Medium: Online Resource
    Pages: XIII, 466 p. 64 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811517020
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Bioinformatics. ; Proteins. ; Pharmacology. ; Computational and Systems Biology. ; Proteins.
    Description / Table of Contents: 1 Computational Approaches in Drug Discovery and Design -- 2 Molecular Modeling of Proteins: Methods, Recent Advances and Future Prospects -- 3 Cavity/Binding Site Prediction Approaches, and their Applications -- 4 Role of ADMET Tools in Current Scenario; Application and Limitations -- 5 Database Resources for Drug Discovery -- 6 Molecular Docking and Structure-Based Drug Design -- 7 Molecular Dynamics Simulation of Protein and Protein-Ligand Complexes -- 8 Computational Approaches for Drug Target Identification -- 9 Computational Screening Techniques for Lead Design and Development -- 10 Advances in Pharmacophore Modeling and its Role in Drug Designing -- 11 In Silico Designing of Vaccines: Methods, Tools and Their Limitations -- 12 Machine learning Approaches to Rational Drug Design. .
    Abstract: This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.
    Type of Medium: Online Resource
    Pages: XIII, 306 p. 80 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811568152
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmacy. ; Medical sciences. ; Drug development. ; Pharmacology. ; Pharmacy. ; Preclinical Research.
    Description / Table of Contents: Chapter 1. Introduction to mammalian circadian clock system -- Chapter 2. Introduction to pharmacokinetics -- Chapter 3. Circadian clock and metabolic diseases -- Chapter 4. Circadian clock and CYP metabolism -- Chapter 5. Circadian clock and non-CYP phase I metabolism -- Chapter 6. Circadian clock and phase II metabolism -- Chapter 7. Circadian clock and uptake transporters -- Chapter 8. Circadian clock and efflux transporters -- Chapter 9. Role of pharmacokinetics in chronotherapeutics -- Chapter 10. Role of non-pharmacokinetic factors in chronoefficacy.
    Abstract: This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.
    Type of Medium: Online Resource
    Pages: VII, 253 p. 59 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811588075
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Neurosciences. ; Cardiology. ; Oncology. ; Pharmacology. ; Neuroscience. ; Cardiology. ; Oncology.
    Description / Table of Contents: 1. Quality in Non-GxP Research Environment -- 2. Guidelines & Initiatives for Good Research Practice -- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices -- 4. General Principles of Preclinical Study Design -- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research -- 6. Blinding and Randomization -- 7. Out of control? Managing baseline variability in experimental studies with control groups -- 8. Quality of Research Tools -- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies -- 10. Building robustness intro translational research -- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research -- 12. Minimum Information in In Vivo Research -- 13. A reckless guide to P-values: Local evidence, global errors -- 14. Electronic Lab Notebooks and Experimental Design Assistants -- 15. Data storage -- 16. Design of meta-analysis studies -- 17. Publishers’ responsibilities in promoting data quality and reproducibility -- 18. Quality governance in biomedical research -- 19. Good Research Practice – Lessons from Animal Care & Use -- 20. Research collaborations and quality in research: foes or friends? -- 21. Costs of implementing quality in research practice.
    Abstract: This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
    Type of Medium: Online Resource
    Pages: X, 423 p. 34 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030336561
    Series Statement: Handbook of Experimental Pharmacology, 257
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Pharmacology.
    Description / Table of Contents: 1. Methods for Population Research on Substance Use and Consequences -- 2. Translational Molecular Approaches in Substance Abuse Research -- 3. Small Molecule Neuropeptide-S and Melanocortin Receptor Ligands As Potential Treatments for Substance Use Disorders -- 4. Emerging Insights into Mu Opioid Pharmacology -- 5. Behavioral Pharmacology of Drugs Acting at Mu Opioid Receptors -- 6. The Rise and Fall of Kappa-Opioid Receptors in Drug Abuse Research -- 7. Clinical Trials for Opioid Use Disorder -- 8. Modelling Differential Vulnerability to Substance Use Disorder in Rodents: Neurobiological Mechanisms -- 9. Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder -- 10. Molecular Mechanisms of Amphetamines -- 11. Clinical Trials for Stimulant Use Disorders: Addressing Heterogeneities That May Undermine Treatment Outcomes -- 12. Molecular Mechanism and Cannabinoid Pharmacology -- 13. Pharmacotherapies for Cannabis Use Disorders: Clinical Challenges and Promising Therapeutic Agents -- 14. Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence -- 15. Randomized Clinical Trials Investigating Innovative Interventions for Smoking Cessation in the Last Decade -- 16. Adolescent Vulnerability to Alcohol Use Disorder: Neurophysiological Mechanisms from Preclinical Studies -- 17. Medication Development for Alcohol Use Disorder: A Focus on Clinical Studies -- 18. Newly Emerging Drugs of Abuse.
    Abstract: The purpose of this book is to provide a broad scope of substance use disorder research and how these findings can impact treatment outcomes. The research and outcomes described in this book represent important principles related to identifying and understanding factors related to substance use disorders. The first section is dedicated to methodology including population-based surveys, basic neuroanatomy, chemistry, molecular biology, behavioral models and brain imaging. The second section utilizes this methodology in research related to opioids, cocaine, marijuana, alcohol and nicotine. The book is aimed at both professionals (academics, clinicians, practitioners) and students or trainees.
    Type of Medium: Online Resource
    Pages: X, 502 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030336790
    Series Statement: Handbook of Experimental Pharmacology, 258
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Immunology. ; Nanotechnology. ; Pharmacology. ; Immunology. ; Nanotechnology.
    Description / Table of Contents: Overview of immune response to nanomaterials caused by either inhalation, oral, or dermal exposure -- Engineered nanomaterials: synthesis, characterization, uses and exposure -- Impact of nanomaterials on barrier function -- Complement activation and inflammation -- Macrophage function and phagocytosis -- Mast cells -- Impact on dendritic cell - lymphocyte function -- Impact on host pathogen response and microbiome -- Allergy/autoimmunity -- Pre-existing allergic or bacterial-induced lung disease -- Nanomaterial effects on viral infection -- Immunotoxicity and carcinogenesis -- In vivo animal models (nude mice, transgenic models) -- In vitro cell culture models -- In silico computational modeling -- Summary of mechanisms of immune modulation. .
    Abstract: This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative testing strategies for evaluating immunotoxicity of ENMs. .
    Type of Medium: Online Resource
    Pages: X, 223 p. 16 illus., 5 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339623
    Series Statement: Molecular and Integrative Toxicology,
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Cytology. ; Cytokines. ; Diseases. ; Proteins. ; Endocrinology. ; Pharmacology. ; Cell Biology. ; Cytokines and Growth Factors. ; Diseases. ; Proteins. ; Endocrinology.
    Description / Table of Contents: The cells of bone their interactions -- Parathyroid hormone and bone -- Vitamin D and bone -- Gonadal hormones and bone -- Thyroid hormones, glucocorticoids, insulin, and bone -- Growth factors and bone -- Prostaglandins and bone -- Cytokines and bone: osteoimmunology -- Chemokines and bone -- Calcium and bone -- FGF-23 and bone and mineral metabolism -- Nervous system mediators and bone -- Genetics of bone disorders -- Osteoporosis pathogenesis -- Structural and metabolic assessment of bone status -- Osteoporosis Therapeutics 2019 -- New targets and emergent therapies for osteoporosis -- Drugs causing bone loss -- Natural Products as potential bone therapies.
    Abstract: This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments. .
    Type of Medium: Online Resource
    Pages: X, 518 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030573782
    Series Statement: Handbook of Experimental Pharmacology, 262
    DDC: 615
    Language: English
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    Keywords: Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Environmental chemistry. ; Environmental management. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Water. ; Freshwater and Marine Ecology. ; Environmental Chemistry. ; Environmental Management. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Section I. Introduction -- 1. Introduction to the Volume -- Section II. Physics and Chemistry of Deep Oil Well Blowouts -- 2. The importance of understanding fundamental physics and chemistry of deep oil blowouts -- 3. Physical and chemical properties of oil and gas under reservoir and deep-sea conditions -- 4. Jet formation at the blowout site -- 5. Behavior of rising droplets and bubbles – impact on the physics of deep-sea blowouts and oil fate -- Section III. Transport and Degradation of Oil and Gas from Deep Spills -- 6. The importance of understanding transport and degradation of oil and gasses from deep sea blowouts -- 7. Biodegradation of petroleum hydrocarbons in the deep sea -- 8 Partitioning of organics between oil and water phases with and without the application of dispersants -- 9. Dynamic coupling of near-field and far-field models -- 10. Effects of oil properties and slick thickness on dispersant field effectiveness and oil fate -- 11. Far-field modeling of a deep-sea blowout: sensitivity studies of initial conditions, biodegradation, sedimentation and sub-surface dispersant injection on surface slicks and oil plume concentrations -- Section IV. Oil Spill Records in Deep Sea Sediments -- 12. Formation and sinking of MOSSFA (Marine Oil Snow Sedimentation and Flocculent Accumulation) events: Past and Present -- 13. The sedimentary record of MOSSFA events in the Gulf of Mexico: A comparison of the Deepwater Horizon (2010) and Ixtoc 1 (1979) oil spills -- 14. Characterization of the sedimentation associated with the Deepwater Horizon blowout: depositional pulse, initial response, and stabilization -- 15. Applications of FTICR-MS in oil spill studies -- 16. Changes in redox conditions of surface sediments following the Deepwater Horizon and Ixtoc 1 events -- 17. Long-term preservation of oil spill events in sediments: the case for the Deepwater Horizon spill in the northern Gulf of Mexico -- 18. Effect of marine snow on microbial oil degradation -- 19. Molecular legacy of the 1979 Ixtoc 1 oil spill in deep-sea sediments of the southern Gulf of Mexico -- 20. 40 years of weathering of coastal oil residues in the southern Gulf of Mexico -- Section V. Impacts of Deep Spills on Plankton, Fishes, and Protected Resources -- 21. Overview of ecological impacts of deep spills -- 22. Deep-sea benthic faunal impacts and community evolution before, during and after the Deepwater Horizon event -- 23. Impact and resilience of benthic foraminifera in the aftermath of the Deepwater Horizon and Ixtoc 1 oil spills -- 24. Chronic sublethal effects observed in wild caught fish following two major oil spills in the Gulf of Mexico: Deepwater Horizon and Ixtoc 1 -- 25. Impacts of deep spills on fish and fisheries -- 26. Impacts of the Deepwater Horizon oil spill on marine mammals and sea turtles -- Section VI. Toxicology of Deep Oil Spills -- 27. Ecotoxicology of deep ocean spills -- 28 A synthesis of Deepwater Horizon oil, chemical dispersant and chemically dispersed oil aquatic standard laboratory acute and chronic toxicity studies -- 29. Digging deeper than LC/EC50: non-traditional endpoints and non-model species in oil spill toxicology -- 30. Genetics and oil: transcriptomics, epigenetics and population genomics as tools to understand animal responses to exposure across different time scales -- Section VI. I Ecosystem-level modeling of deep oil spill impacts -- 31. A synthesis of top down and bottom up impacts of the Deepwater Horizon oil spill using ecosystem modeling -- 32. Comparing ecosystem model outcomes between Ixtoc 1 and Deepwater Horizon oil spills -- 33. Effects of the Deepwater Horizon oil spill on Human Communities: Catch and Economic Impacts -- Section VIII. Summary -- 34. Summary of Major Themes – Deep Oil Spills -- Index.
    Abstract: The demand for oil and gas has brought exploration and production to unprecedented depths of the world’s oceans. Currently, over 50% of the oil from the Gulf of Mexico now comes from waters in excess of 1,500 meters (one mile) deep, where no oil was produced just 20 years ago. The Deepwater Horizon oil spill blowout did much to change the perception of oil spills as coming just from tanker accidents, train derailments, and pipeline ruptures. In fact, beginning with the Ixtoc 1 spill off Campeche, Mexico in 1979-1980, there have been a series of large spill events originating at the sea bottom and creating a myriad of new environmental and well control challenges. This volume explores the physics, chemistry, sub-surface oil deposition and environmental impacts of deep oil spills. Key lessons learned from the responses to previous deep spills, as well as unresolved scientific questions for additional research are highlighted, all of which are appropriate for governmental regulators, politicians, industry decision-makers, first responders, researchers and students wanting an incisive overview of issues surrounding deep-water oil and gas production.
    Type of Medium: Online Resource
    Pages: XIV, 611 p. 152 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030116057
    DDC: 551.48
    Language: English
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    Keywords: Natural disasters. ; Environmental monitoring. ; Human geography. ; Climatology. ; Geographic information systems. ; Natural Hazards. ; Environmental Monitoring. ; Human Geography. ; Climate Sciences. ; Geographical Information System.
    Description / Table of Contents: External Interventions for Enhancing Community Resilience: An Overview of Planning Paradigms -- Lessons Learned from Interventions of External Organizations in Disaster Management: A Case Study of Floods in Kalutara, Sri Lanka -- Dependency on External Supports: An Addition to Community Vulnerability -- Sustainable Development through Post-Disaster Reconstruction: A Unique Example in Sri Lanka -- Local Community Engagement for Adaptation to Future Challenges in The Pilot Flood Detention Area of Thailand -- Traditional Practices, Communities’ Aspirations, and Reconstructed End Products: Analyzing the Post-Sidr Reconstruction in the Coastal Region of Bangladesh -- Designing Spaces with Victims of Humanitarian Crisis: Action Research on Spaces for Children at Rohingya Camps in Bangladesh -- Disaster Risk Reduction in Cities: Towards A New Normal -- Disaster Risk Reduction in Cities: Towards A New Normal -- Rethinking Roles of Local Non-Governmental Organizations (LNGO) in Managing Disaster Risks in Historic Neighborhoods: Experiences from the City of Lagos, Nigeria -- A Complexity Approach for Reducing Disaster Risks for Marginalized Urban Populations: Comparing DRR Interventions across Four Cities -- Adaptation and Development for Mitigating Impacts of Climate Change and Climate Extremes -- Public and Private Sector Interventions in Post-Disaster Resettlement: A Case Study of Model Villages in Pakistan -- Effectiveness of Disaster Risk Reduction (DRR) and Climate Change Adaptation (CCA) Training Programs: Views and Voices from Barisal Division, a Coastal Region in Bangladesh -- To ‘Float’ or ‘Not’: Cases of Amphibious Housing and Their Impacts on Vulnerable Communities of Jamaica.
    Abstract: This book presents a case study-based analysis of the consequences of external interventions, critically evaluating them from community perspectives. Communities – from rural to urban, and around the world – that are experiencing disasters and changes in climatic variables can perceive the associated risks and evaluate the impacts of interventions. Accordingly, community perspectives, including their perceptions, concerns, awareness, realizations, reactions and expectations, represent a valuable resource. The case-based analysis of impacts on communities can provide a ‘means of learning’ from the experiences of others, thus expanding professionals’ knowledge base, especially regarding disaster mitigation and climate change adaptation practices in varied settings. This book offers valuable insights and lessons learned, in an effort to promote and guide innovative changes in the current planning, management and governance of human settlements, helping them face the future challenges of a changing environment. .
    Type of Medium: Online Resource
    Pages: XX, 296 p. 65 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811549489
    Series Statement: Advances in 21st Century Human Settlements,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Water. ; Hydrology. ; Energy policy. ; Energy and state. ; Pollution. ; Geology. ; Water. ; Energy Policy, Economics and Management. ; Pollution.
    Description / Table of Contents: 1. Introduction -- 2. Water Works of Ancient Civilizations -- 3. Water Resources Development -- 4. Climate and Drought -- 5. Hydrology of Surface Waters -- 6. Groundwater -- 7. Water quality -- 8. Water Potential of Turkey -- 9. Agricultural Water Use -- 10. Water and Energy -- 11. Urban, Industrial, Environmental and Other Water Uses -- 12. Legal and institutional structure of water management -- 13. Transboundary River Basins. 14. Basin management -- 15. Impacts of Climate Change -- 16. Challenges for the future.
    Abstract: This book provides an in-depth description of water resources of Turkey, a country with a unique geographical location, extending from the Mediterranean in Europe to the Middle East. Its varying geography, topography, hydrology, geology and climate are reflected in the diverse characteristics of its water basins. Furthermore, due to its geographical location, Turkey has a significant number of transboundary river basins and has to share its water resources with its neighbors, an issue that can sometimes lead to water conflicts. Turkey is also an interesting example of a developing country that is attempting to adapt to universal water management strategies while at the same time facing legal, institutional, economic and capacity development problems. It has long remained a water-rich country, but the situation is now changing due to the increasing population, inefficient use of resources, and the impacts of climate change and environmental degradation. This book is useful for national and international organizations as well as water resources professionals. It takes on an added significance in the light of climate change in the region, water management problems and transboundary water basins.
    Type of Medium: Online Resource
    Pages: XXI, 545 p. 204 illus., 162 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030117290
    Series Statement: World Water Resources, 2
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Water. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Introduction -- 1.Physical Properties of Water -- 2.An Overview of Hydrology -- 3.Water Temperature -- 4.Dissolved Solids -- 5.Particulate Matter, Color, Turbidity, and Light -- 6.Dissolved Oxygen and Other Gases -- 7.Redox Potential -- 8.pH, Carbon Dioxide, and Alkalinity -- 9.Acidity -- 10.Total Hardness -- 11.Microorganisms, Macrophytes, and Water Quality -- 12.Nitrogen -- 13.Phosphorus -- 14.Eutrophication -- 15.Sulfur -- 16.Micronutrients and Other Trace Elements -- 17.Water Supply -- 18.Water Pollution -- 19.Water Quality Regulations.
    Abstract: This volume is of great importance to humans and other living organisms. The study of water quality draws information from a variety of disciplines including chemistry, biology, mathematics, physics, engineering, and resource management. University training in water quality is often limited to specialized courses in engineering, ecology, and fisheries curricula. This book also offers a basic understanding of water quality to professionals who are not formally trained in the subject. The revised third edition updates and expands the discussion, and incorporates additional figures and illustrative problems. Improvements include a new chapter on basic chemistry, a more comprehensive chapter on hydrology, and an updated chapter on regulations and standards. Because it employs only first-year college-level chemistry and very basic physics, the book is well-suited as the foundation for a general introductory course in water quality. It is equally useful as a guide for self-study and an in-depth resource for general readers.
    Type of Medium: Online Resource
    Pages: XI, 440 p. 115 illus., 6 illus. in color. , online resource.
    Edition: 3rd ed. 2020.
    ISBN: 9783030233358
    DDC: 551.48
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Natural disasters. ; Statistics . ; Natural Hazards. ; Applied Statistics.
    Description / Table of Contents: Introduction -- Individual and Extreme Risk -- Systemic Risk and Dependencies -- Application. .
    Abstract: This book is about how extreme and systemic risk can be analyzed in an integrated way. Risk analysis is understood to include measurement, assessment as well as management aspects. Integration is understood as being able to perform risk analysis for extreme and systemic events simultaneously. The presented approach is based on Sklar's theorem, which states that a multivariate distribution can be separated into two parts – one describing the marginal distributions and the other describing the dependency between the distributions using a so-called copula. It is suggested to reinterpret Sklar's theorem from a system or network perspective, treating copulas as a network property and individual, including extreme, risk as elements within the network. In that way, extreme and systemic risk can be analyzed independently as well as jointly across several scales. The book is intended for a large audience, and all techniques presented are guided with examples and applications with a special focus on natural disaster events. Furthermore, an extensive literature and discussion of it are given in each chapter for the interested reader.
    Type of Medium: Online Resource
    Pages: XI, 156 p. 54 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811526893
    Series Statement: Integrated Disaster Risk Management,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Natural disasters. ; Geographic information systems. ; Human geography. ; Natural Hazards. ; Geographical Information System. ; Human Geography.
    Description / Table of Contents: 1.Identifying and mapping flood risk in urban areas -- 2.Identifying and mapping the risk of rockfall and landslide on roads and urban areas -- 3.Identifying and mapping the risk of local subsidence.
    Abstract: This book proposes a methodology for the identification of flooding in urban areas, by the denomination of 1) urban hydrographic basin; and 2) polygon of flood risk. This work will enable readers to elaborate a preventive program in Latin America and analogous regions. The authorities could use it as a basis to create urban planning strategies or preventive programs to reduce or eliminate the flooding hazard. The growth of an urban area implies that the natural terrain is covered by an asphalt folder, which results in an Urban Hydrographic Basin where rainwater drains down its streets filtering through sewers towards rainwater drains or wastewater. Initially, the drainages are calculated according to the population in a specific urban area, however, the population growth causes the growth of the urban area, where the old drainages and new roads are linked, causing their saturation and chaos. More water runs down the streets and is accumulated in the lower areas, causing flooding.
    Type of Medium: Online Resource
    Pages: XIX, 58 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030224721
    Series Statement: SpringerBriefs in Earth Sciences,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Natural disasters. ; Sociology, Urban. ; Geographic information systems. ; Earth sciences. ; Natural Hazards. ; Urban Sociology. ; Geographical Information System. ; Earth Sciences.
    Description / Table of Contents: Part I: Hydrogeology and Aquifer Contamination -- Chapter 1. Geological and hydrogeological characterization of springs in a DSGSD context (Rodoretto Valley - NW Italian Alps) (Martina Gizzi, Stefano Lo Russo, Maria Gabriella Forno, Elena Cerino Abdin, Glenda Taddia) -- Chapter 2. Evaluation and prediction of seepage discharge through tailings dams when their rising (Viacheslav V. Fetisov, Elena A. Menshikova) -- Chapter 3. Sediment yield in mountain basins, analysis and management: the SMART-SED project (Davide Brambilla, Monica Papini, Vladislav Ivov Ivanov, Luca Bonaventura, Andrea Abbate, Laura Longoni) -- Chapter 4. Natural groundwater background levels of nitrate and landfill effects (Apulia, Southern Italy) (Livia Emanuela Zuffianò, Pier Paolo Limoni, Giorgio De Giorgio, Maurizio Polemio) -- Part II: Geology and Urban areas -- Chapter 5. Sinkholes in the Friuli Venezia Giulia Region focus on the evaporites (Chiara Calligaris, Luca Zini, Stefania Nisio, Chiara Piano) -- Chapter 6. Collapses in calcarenitic deposits along the sides of the Ginosa ravine in south Italy (Angelo Doglioni, Vincenzo Simeone) -- Chapter 7. Relation between on field and InSAR data on landslide-induced damage (Matteo Del Soldato, Silvia Bianchini, Pantaleone De Vita, Diego Di Martire, Roberto Tomás, Domenico Calcaterra, Nicola Casagli) -- Chapter 8. A hierarchical model for the Rocca di Sciara north-eastern slope instabilities (Sicily, Italy) (Mario Valiante, Francesca Bozzano, Marta Della Seta, Domenico Guida) -- Part III: Geomechanics -- Chapter 9. Comparing direct and indirect methods to estimate Uniaxial Compressive Strength of rocks belonging to the Dolomites sequence (NE Italian Alps) (Elia Longo, Ennio Chiesurin, Mario Floris) -- Chapter 10. CO2 sequestration and enhanced coalbed methane recovery: Worldwide status and Indian scenario (Bankim Mahanta, Vikram Vishal) -- Part IV: Landslide: Monitoring -- Chapter 11. Hydrological behavior of unsaturated shallow soils on a slope and its failure mechanism: a case study in Ren River catchment, China (Xinsheng Wei, Wen Fan, Massimiliano Bordoni, Claudia Meisina) -- Chapter 12. First steps for the development of an optical fibre strain sensor for shallow landslide stability monitoring through laboratory experiments (Monica Papini, Vladislav Ivov Ivanov, Davide Brambilla, Maddalena Ferrario, Marco Brunero, Gabriele Cazzulani, Laura Longoni) -- Chapter 13. The giant Seymareh Landslide (Zagros Mts., Iran): a lesson for evaluating multi-temporal hazard scenarios (Michele Delchiaro, Javad Rouhi, Marta Della Seta, Salvatore Martino, Reza Nozaem, Maryam Dehbozorgi) -- Chapter 14. Towards real-time geodetic monitoring of landslides with GNSS mass-market devices (Paolo Dabove, Ambrogio M. Manzino, Alberto Cina, Marco Piras, Iosif H. Bendea) -- Part V: Landslide: Climate change -- Chapter 15. Italian latest advances on rainfall thresholds for landslide triggering (Stefano Luigi Gariano, Samuele Segoni, Luca Piciullo) -- Chapter 16. Validation of a shallow landslide susceptibility analysis through a real case study: an example of application in Rome (Italy) (Poueme Djueyep Geraud, Esposito Carlo, Schilirò Luca, Bozzano Francesca) -- Part VI: Landslide: Control -- Chapter 17. Application of a generalized criterion: time-of-failure forecast and alert thresholds assessment for landslides (Alessandro Valletta, Andrea Segalini, Andrea Carri) -- Chapter 18. Evaluation of prediction capability of the MaxEnt and Frequency Ratio methods for landslide susceptibility in the Vernazza catchment (Cinque Terre, Italy) (Emanuele Raso, Diego Di Martire, Andrea Cevasco, Domenico Calcaterra, Patrizio Scarpellini, Marco Firpo).
    Abstract: This book includes a careful selection of significant contributions from international experts that were presented at the 6th AIGA Conference “Applied Geology: Approaches to Future Resource Management” that was held in the Courmayeur, Aosta Valley, Italy, from 27 - 29 June 2018. The following 7 areas are the main themes covered in this volume: · Applied Geology · Hydrogeology · Geological Exploration (underground) · Slope Instability, · Natural Hazards, Risk Assessment and Management, · Geo-resources and Sustainable Development · Application of Remote Sensing and Geographical Information Systems (GIS) The authors, from academia, research and industry present the latest state of the practice, new technologies, innovative methods and sustainable management in the field of Applied and Environmental Geology. This carefully edited work will be of value to academia, professionals, scientists and decision makers.
    Type of Medium: Online Resource
    Pages: XVII, 316 p. 138 illus., 118 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030439538
    DDC: 551
    Language: English
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    Keywords: Geology. ; Paleontology . ; Paleoecology. ; Geology. ; Paleontology. ; Paleoecology.
    Description / Table of Contents: Introduction -- Strata -- Igneous rocks -- Geological structure and tectonic evolution -- Conclusions.
    Abstract: This Open Access book introduces readers to the regional geology of Hanggai, Xianxia and Chuancun, the area between China's northern Zhejiang Province and southern Anhui Province and explores the strata, magmatic rocks and tectonic structures in 1:50,000 scale geological maps. Based on studies of multiple stratigraphic divisions, the standard stratigraphic section of the upper Ordovician Hirnantian in the lower Yangtze region is established, revealing for the first time numerous “Burgess Shale-type” sponge fossils in Hirnantian strata and identifying 10 grapholite fossil belts and various fossil categories, including chitin, trilobites, gastropods, brachiopods, and cephalopods. Moreover, the book identifies for the first time Late Ordovician volcanic events in northern Zhejiang province. The work represents a major contribution to research on Paleozoic strata in the Lower Yangtze region, and sheds new light on understanding the Hirnantian glacial event and biological extinction event in South China by providing a high-precision time scale. In addition, the book opens an important avenue for future research on sponge evolution after the Cambrian life explosion. As such, it offers a unique and valuable asset for researchers and graduate students alike.
    Type of Medium: Online Resource
    Pages: VII, 292 p. 268 illus., 122 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811517884
    Series Statement: The China Geological Survey Series,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Physical geography. ; Geology. ; Physical Geography.
    Description / Table of Contents: Structural-Geological Mapping of Karst Area -- Late Cretaceous and Paleogene Paleokarsts of the Northern Sector of the Adriatic Carbonate Platform -- Lithomorphogenesis of Karst Surface -- Significant Findings from Karst Sediment Research -- Measurements of Present-Day Limestone Dissolution and Calcite Precipitation Rates with Limestone Tablets in Stream Caves (with the Case Study of Škocjanske Jame) -- Water Quality Monitoring in Karst -- Planning Contamination Emergency Response Measures for Karst Water Sources -- Deciphering Epiphreatic Conduit Geometry from Head and Flow Data -- Microbial Underground; Microorganisms and Their Habitats in Škocjan Caves -- Changing Perspectives on Subterranean Habitats -- Research Infrastructures and Karst Science.
    Abstract: This book presents the latest advances in karstology by researchers at the ZRC SAZU Karst Research Institute, Slovenia – home of Classical Karst. It features interdisciplinary investigations carried out on the karst surface, subsurface, caves, and associated waters. It covers various topics, such as analysis of karst processes, including the mineralogical and lithological characteristics of sediments and carbonate rocks; structural geological mapping; detecting the old traces of paleokarst; the formation of karst surfaces in a variety of types of rock and conditions; and the evolution of karst, which can aid in dating sediments, and in tracing aquifers using artificial and natural tracers. In addition, the book provides detailed information on the use and development of various research methods, ranging from comprehensive field research, long-term measurements, and laboratory analyses to computer and laboratory modeling. Integrating karst geology, geomorphology, hydrology, ecology, speleobiology, and microbiology research, these methods provide readers with a far deeper understanding of karst terrains.
    Type of Medium: Online Resource
    Pages: XII, 222 p. 195 illus., 165 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030268275
    Series Statement: Advances in Karst Science,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Physical geography. ; Environment. ; Geology. ; Physical Geography. ; Environmental Sciences.
    Abstract: This book presents selected papers from the EuroKarst 2018 conference, which highlighted the latest advances in the field of Karst Hydrogeology and Carbonate Reservoirs. The event attracted more than 180 participants. From among their contributions, the papers were selected and subsequently reviewed by the scientific committee to ensure the highest possible quality.
    Type of Medium: Online Resource
    Pages: XI, 249 p. 160 illus., 143 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030140151
    Series Statement: Advances in Karst Science,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Sedimentology. ; Geochemistry. ; Geology. ; Sedimentology. ; Geochemistry.
    Description / Table of Contents: Introduction -- Regional Geology across the Solonker Suture Zone -- Methodology -- Results -- Geochronological Entropy, and its Relevance to Age Measurements -- Accretionary Collision between the Mongolian Arcs and North China Craton -- Conclusions.
    Abstract: This Ph.D. thesis attempts to decipher the closure of the Palaeozoic Palaeo-Asian Ocean along the enigmatic Solonker Suture in East Asia adopting a methodology that integrates geochemical and geochronological data from Palaeozoic sedimentary and volcanic rocks in the region. It provides an in-detail but also broad insight into the Palaeozoic to early Mesozoic tectonic evolution of the region, not only pin-pointing the debated location of the Solonker Suture but also the timing of final disappearance of the Palaeo-Asian Ocean during Permian to Early Triassic times. The results have led to propose a tectonic ‘soft-collision’ model for the amalgamation of the North China Craton and the Mongolian Terranes in northern Asia explaining the general absence of geologic features characteristic for continent-continent collisions such as the occurrence of regional-scale high-grade metamorphic rocks, ophiolite belts and fold-thrust structures. This new model may serve as a blueprint for the tectonic evolution of similar suture zones that are characterized by the absence of typical collision related lithologies and structures. The thesis is particularly useful as a guide for researchers who seek an in-depth understanding of the Palaeozoic to early Mesozoic tectonic evolution of northern China and Central Asia along the Solonker Suture. .
    Type of Medium: Online Resource
    Pages: XXXV, 270 p. 110 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813292000
    Series Statement: Springer Theses, Recognizing Outstanding Ph.D. Research,
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Geology. ; Geophysics. ; Natural Hazards. ; Geology. ; Geophysics.
    Description / Table of Contents: 1. Preface -- 2.Active processes in Iberia: An Introduction -- 3.Active deformation in the Iberian Peninsula from geodetic techniques -- 4.Seismicity of the Iberian Peninsula -- 5. Active faults in Iberia -- 6. Active landscapes of Iberia.
    Abstract: Adopting a global approach, this unique book provides an updated review of the geology of Iberia and its continental margins from a geodynamic perspective. Owing to its location close to successive plate margins, Iberia has played a pivotal role in the geodynamic evolution of the Gondwanan, Rheic, Pangea, Tethys and Eurasian plates over the last 600 Ma of Earth’s history. The geological record starts with the amalgamation of Gondwana in the Neoproterozoic, which was succeeded by the rifting and spreading of the Rheic ocean; its demise, which led to the amalgamation of Pangea in the late Paleozoic; and the rifting and spreading of several arms of the Neotethys ocean in the Mesozoic Era and their ongoing closure, which was responsible for the Alpine orogeny. The significant advances in the last 20 years have increasingly attracted international interest in exploring the geology of the Iberian Peninsula. This final volume of the Geology of Iberia focuses on the active geological processes in Iberia including seismicity and active faulting as well as the modern landscapes in the Iberian Peninsula.
    Type of Medium: Online Resource
    Pages: XVII, 126 p. 41 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030109318
    Series Statement: Regional Geology Reviews,
    DDC: 551
    Language: English
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    Keywords: Geology. ; Mineralogy. ; Sedimentology. ; Geology. ; Mineralogy. ; Sedimentology.
    Description / Table of Contents: History of the Geological Research in Egypt -- Precambrian Geology of Egypt -- Structural and tectonic framework of Neoproterozoic basement of Egypt: from gneiss domes to transpression belts -- Crustal Evolution of the Precambrian rocks of Egypt -- The Precambrian metamorphic belts of Egypt -- Tectonics and Structural Evolution of Egypt -- Red Sea Tectonics -- Paleozoic Geology of Egypt -- Mesozoic Geology of Egypt -- Paleogene Geology of Egypt -- Neogene Geology of Egypt -- Quaternary Geology of Egypt -- Egyptian Vertebrate Paleontology -- Egyptian Impact Crater(s) and Meteorites -- Mineral Resources in Egypt (I): Metallic Ore Depoists -- Mineral Resources in Egypt (II): Non-Metallic Ore Depoists -- Hydrocarbon Resources in Egypt -- Water Resources in Egypt -- Seismicity, Seismotectonics and Neotectonics.
    Abstract: This richly illustrated book offers a concise overview of the geology of Egypt in the context of the geology of the Arab Region and Northeast Africa. An introductory chapter on history of geological research in Egypt sheds much light on the stages before and after the establishment of Egyptian Geological Survey (the second oldest geological survey worldwide), Hume's book and Said's 1962, 1990 books. The book starts with the Precambrian geology of Egypt, in terms of lithostratigraphy and classifications, structural and tectonic framework, crustal evolution and metamorphic belts. A dedicated chapter discusses the Paleozoic-Mesozoic-Cenozoic tectonics and structural evolution of Egypt. A chapter highlights the Red Sea tectonics and the Gulf of Suez and Gulf of Aqaba Rifts. Subsequent chapters address the Phanerozoic geology from Paleozoic to Quaternary. The Egyptian Impact Crater(s) and Meteorites are dealt with in a separate chapter. The Earth resources in Egypt, including metallic and non-metallic ore deposits, hydrocarbon and water resources, are given much more attention throughout four chapters. The last chapter addresses the seismicity, seismotectonics and neotectonics of Egypt.
    Type of Medium: Online Resource
    Pages: XXVI, 711 p. 382 illus., 352 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030152659
    Series Statement: Regional Geology Reviews,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geotechnical engineering. ; Oceanography. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences. ; Ocean Sciences.
    Description / Table of Contents: The Formation Of The «Baer Hillocks» By The Peak Water Flow At A Sharple Reduction Of The Caspian Sea Level -- Features Of The Formation Of Gold Manifestations In The Black Shale Deposits Of The Kumakskoye Ore Field -- Analytical Test Problem Of Wing Currents -- Determination Of The Propagation Speed Of Wave -- A Model Of A Coastal Barrier And Its Application To The Anapa Bay-Bar Coasts.
    Abstract: This book presents the findings of recent theoretical and experimental studies of processes in the atmosphere, oceans and lithosphere, discussing their interactions, environmental issues, geology, problems related to human impacts on the environment, and methods of geophysical research. It particularly focuses on the geomechanical aspects of the production of hydrocarbons, including the laborious extraction of oils. Furthermore, it includes contributions on ecological problems of the biosphere. .
    Type of Medium: Online Resource
    Pages: VII, 317 p. 131 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030381776
    Series Statement: Springer Geology,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Natural disasters. ; Pollution. ; Water. ; Hydrology. ; Physical geography. ; Geology. ; Natural Hazards. ; Pollution. ; Water. ; Earth System Sciences.
    Description / Table of Contents: 1. Introduction -- 2.Flood risk assessment -- 3. Flood damage assessment -- 4. Flood risk management -- 5. Case studies -- 6. Conclusion.
    Abstract: The costs of damages caused by extreme weather events, among which floods are a major category, are showing a rapid upward trend, both globally and in Europe. Scope and extremity of flood episodes point to the need to build a comprehensive proposal including the completion of flood protection measures in areas exposed to flood risk. The aim of flood risk management is to present flood protection measures. This book presents the state of the art of essential knowledge on methods and tools of flood risk assessment and management to young researchers, academics, lecturers and water management practitioners. This book is dedicated to flood damage assessment focused on social, economic and environmental damages management. Its objectives are to develop a general methodology for flood risk assessment and to present a choice of effective flood protection methods according the objectives of flood risk management.
    Type of Medium: Online Resource
    Pages: XIII, 120 p. 46 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030500535
    Series Statement: Water Science and Technology Library, 94
    DDC: 551
    Language: English
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    Keywords: Water. ; Hydrology. ; Animal culture. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Power resources. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Production management. ; Water. ; Animal Science. ; Fossil Fuel. ; Natural Resource and Energy Economics. ; Environmental Engineering/Biotechnology. ; Operations Management.
    Description / Table of Contents: Part 1 – ARCTIC ECOSYSTEMS AND SUSTAINABILITY. Chapter 1 – Sustainability in an Arctic context: Resilience of the Arctic marine environment(Eva Pongrácz) -- Chapter 2 – Thinking like an ocean: A climate ethic for the Arctic marine environment (Øyvind Stokke) -- Chapter 3 - Arctic marine ecosystems, climate change impacts, and governance responses: an integrated perspective from the Barents Sea (Stefan Koenigstein) -- Chapter 4 – Oil vulnerability index, impact on Arctic bird populations (Proposing a method for calculating an oil vulnerability index for the Arctic Seabirds) (Nina J. O’Hanlon, Alexander L. Bond, Neil A. James and Elizabeth A. Masden) -- Chapter 5 – Conflicts between Arctic industries and cetaceans (Charla Barsan and Marianne. H. Rasmussen) -- Part 2 – Transport infrastructure. Chapter 6 – Social responsibility practice of the evolving nature in the sustainable development of Arctic maritime operations (Antonina Tsvetkova) -- Chapter 7– Miles and meters matter: political effects on the shipping routes of measurement techniques in the Arctic (Eda Ayaydin) -- Chapter 8 – Black carbon, maritime traffic and the Arctic (Tommi Inkinen, Olli-Pekka Brunila, Esa Hämäläinen, Vappu Kunnaala-Hyrkki and Katariina Ala-Rämi) -- Chapter 9 – Impact of the Potential Implementation of Unmanned Aerial Vehicles on the Northern Sea Route Safety Monitoring (Nikita Kuprikov, Mihail Kuprikov, Maxim Shishaev, Maxim Polishchuk) -- Part 3 – oil and gas. Chapter 10 – Handling the preparedness challenges for maritime and offshore operations in Arctic waters (Kay Fjortoft and Tor Einar Berg) -- Chapter 11 – Arctic oil spill response technologies: challenges and limitations (Victor Pavlov) -- Chapter 12 – The role of supply vessels in the development of offshore field projects in Arctic waters (Antonina Tsvetkova) -- Chapter 13 – Special rules for the Arctic? The analysis of Arctic-specific safety and environmental regulation of offshore petroleum development in the Arctic Ocean States (Daria Shapovalova) -- Part 4 – LOCAL communities. Chapter 14 – Increasing shipping in the Arctic and local communities’ engagement: A case from Longyearbyen on Svalbard (Julia Olsen, Grete Kaare Hovelsrud and Bjørn Petter Kaltenborn) -- Chapter 15 – Arctic search and rescue: A case study for understanding issues related to training and human factors when working in the North (Derek. D. Rogers, Michael King and Heather Carnahan) -- Chapter 16 – The possibilities and limitations of tourism development in Greenland to contribute to personal socio-economic wellbeing for coastal communities: (Vishakha Tay) -- Chapter 17 – Marine tourism development in the Arkhangelsk region, Russian Arctic: Stakeholder’s perspectives: (Julia Olsen, Marina Nenasheva, Karin Andrea Wigger, Albina Pashkevich, Sonja H. Bickford and Tatiana Maksimova) -- Chapter 18 – Finnish Sami: Is tourism a preservation of indigenous culture? (Samim Akgönül, and Eda Ayaydin) -- Part 5 – sustainable governance. Chapter 19 – Regulation of cargo shipping on the Northern Sea Route: a strategic compliance in pursuing Arctic safety and commercial considerations: (Antonina Tsvetkova) -- Chapter 20 – Resource use conflicts in Arctic waters: A legal perspective: (Amber Rose Maggio) -- Chapter 21 – Red dragon enters the waters of the High North: The making of China-Arctic shipping corridor: (Liisa Kauppila and Tuomas Kiiski).
    Abstract: This book presents the latest scientific views on resource use conflicts in the Arctic seas. The main areas of focus are the biological resources of Arctic seas vs. exploitation of oil and gas resources, and the conflicts in between. In addition, climate change is presented as a stressor, which both limits and facilitates the economic availability of resources in the Arctic. The book is divided into five parts. Part 1 examines Arctic ecosystems, resilience of the marine environment and possible conflicts between industrial sector and biological world. The focus of Part 2 is on transport infrastructure along the northern routes. Issues such as Arctic maritime operations, black carbon and unmanned aerial vehicles are considered. Part 3 focuses on resource use conflicts in Arctic seas and on the most recent threats in terms of Arctic oil and gas exploration, offshore logistics operations as well as transportation of oil and oil products. Discussions in Part 4 of the book are concentrated around social aspects and involvement of local communities. Tourism development, preservation of indigenous culture, engagement of communities on relevant Arctic issues, search and rescue in the cold marine environment are examples of questions raised. The book reviews Arctic-specific petroleum regulations, the state of preparedness to oil spill accidents in the region as well as the latest developments in oil spill response technologies and their limitations. Search and rescue operations are reviewed and how working in this harsh Arctic environment affects the ability of rescue technicians to perform the required technical skills. Part 5 considers the sustainability challenges arising from the marine resource exploitation. The focus is on the vulnerability of Arctic ecosystems to disturbance – both natural and anthropogenic.
    Type of Medium: Online Resource
    Pages: XV, 489 p. 48 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030284046
    Series Statement: Springer Polar Sciences,
    DDC: 551.48
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Water. ; Hydrology. ; Climatology. ; Geographic information systems. ; Geology. ; Water. ; Climate Sciences. ; Geographical Information System.
    Description / Table of Contents: List of Figures -- List of Tables -- List of Photographs -- Preface -- Acknowledgments -- Chapter 1 Introduction -- Part I Geomorphology and Geology -- Chapter 2 Geomorphology -- Chapter 3 Geology -- Part II Climatic Conditions and Water Balance -- Chapter 4 Climatic Conditions -- Chapter 5 Water Balance -- Part III Conventional Water Resources -- Section A Surface Water Resources -- Chapter 6 Floods -- Chapter 7 Springs -- Chapter 8 Aflaj -- Section B Groundwater Resources -- Chapter 9 Limestone Aquifers -- Chapter 10 Ophiolite Aquifer -- Chapter 11 Gravel Aquifer -- Chapter 12 Sand Aquifer -- Chapter 13 Gravel and Sand Aquifer -- Part IV Non-Conventional Water Resources -- Chapter 14 Desalination Water -- Chapter 15 Treated Sewage Water -- Part V Water Problems -- Chapter 16 General Water Problems -- Chapter 17 Drinking Water Problems -- Chapter 18 Pollution of the Quaternary Sand Aquifer -- Part VI Integrated Water Resources Management -- Chapter 19 Water Conservation -- Chapter 20 Water Harvesting -- Chapter 21 Advanced Agricultural Technologies -- Part VII Modern Techniques in Water Studies -- Chapter 22 Remote Sensing -- Chapter 23 Geographic Information Systems -- Chapter 24 Natural Isotopes -- Chapter 25 Modelling Techniques -- Chapter 26 Water Laws in the United Arab Emirates -- Chapter 27 General Summary -- References.
    Abstract: This book provides an inventory of water resources, describes water challenges, and suggests methodologies and technologies for integrated water resources management in the UAE. It also summarizes efforts of water conservation and management, and modern approaches for improvement of water resources management and decision-making related to this valuable resource. The authors are specialized in geology and hydrogeology and have been teaching and conducting scientific research on water resources in the UAE for the last three decades. This book represents the main reference on water resources in the UAE for academia, researchers, professionals, students and the general public. .
    Type of Medium: Online Resource
    Pages: LXXXI, 850 p. 460 illus., 370 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030316846
    Series Statement: World Water Resources, 3
    DDC: 551
    Language: English
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    Keywords: Geology. ; Geotechnical engineering. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Introduction -- Paleosedimentary Environments And Karst Characteristics Of Ordovician Limestone In North China Coalfields -- Water-Bearing And Water-Resisting Properties Of Top Of Ordovician Limestone In North China Coalfields -- Utilizability Of Weathered And Filled Zone Of Top Of Ordovician Limestone In North China Coalfields -- Criterion For Utilization And Grouting Reconstruction Of Top Of Ordovician Limestone -- Technical System Of Grouting Reconstruction Of Top Of Ordovician Limestone -- Case Study Of Utilization And Grouting Reconstruction Of Top Of Ordovician Limestone -- Conclusions And Innovation Points.
    Abstract: This book examines the water resistance capacity of the Upper Ordovician limestone and its feasibility as a water barrier to achieve safe and green mining. Mine water inrush events often occur during coal mine construction and production; they account for a large proportion of the coal mine disasters and accidents in China, second only to gas explosions. As mining depths and mining intensity continue to increase, the hydrogeological conditions encountered are becoming more complex. This book describes in-situ methods designed to test the water resistance of the limestone layer, as well as specific grouting techniques developed to transform this layer into a barrier that can prevent water inrush during mining. The innovative technologies, which were applied and validated in two coal mines, are applicable to other coal mines or any underground engineering works.
    Type of Medium: Online Resource
    Pages: XVI, 183 p. 98 illus., 83 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030401160
    Series Statement: Springer Theses, Recognizing Outstanding Ph.D. Research,
    DDC: 551
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Geophysics. ; Mineralogy. ; Geology. ; Geophysics. ; Mineralogy.
    Description / Table of Contents: The Research History of the Puchezh-Katunki Structure -- Geological Framework of the Impact Site -- Interior Structure and Composition of Impact-generated and Impact-transformed -- Processes of Transformations of Crystalline Rocks of the Central Uplift -- Dynamic Modeling of the Puchezh-Katunki Impact Structure.
    Abstract: This book presents essential data on the geology of the Puchezh-Katunki crater – an early Jurassic crater located on the East European Platform, with an impact structure that is ca. 80 km in diameter. Offering a comprehensive guide, it reviews the studies carried out during the last several decades on this prominent but not well-known impact structure. It offers the international community state-of-the-art information on the crater with regard to e.g. structural mapping, drilling (including the Vorotilovo well, which is 5374 m deep), geophysical research, and the petrological analysis of impactites and various breccias. In addition, the book includes new results from the mineralization and crystallizations beneath this large impact crater, and suggests new models for crater formations.
    Type of Medium: Online Resource
    Pages: XII, 213 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030320430
    Series Statement: Impact Studies
    DDC: 551
    Language: English
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    Keywords: Natural disasters. ; Sustainability. ; Geophysics. ; Geotechnical engineering. ; Geology. ; Natural Hazards. ; Sustainability. ; Geophysics. ; Geotechnical Engineering and Applied Earth Sciences. ; Geology.
    Description / Table of Contents: Regional Perspectives on Disaster Resilience and Sustainable Development -- Earthquake Risk Assessment in Momase Region of Papua New Guinea using GIS -- Spatio-Temporal Variability of Landslides in the Sikkim Himalaya, India -- Geo Spatial Approach for likelihood damage assessment of buildings due to seismic hazard in urbanized areas -- Perspective of Science and Technology in Disaster Management and Mitigation -- Application of remote sensing & GIS in flood vulnerability assessment - A case study of Lower Ajay Basin, India -- Stable Isotopes and Groundwater Dynamics of the Shallow Ping River Alluvial System in Kamphaeng Phet Riverbank Filtration (RBF) Prospecting Site, Upper Central Thailand -- Risk identification, Assessment and Management of a Building Information Modelling (BIM) implemented project -- Identification of arsenic hazard locations and impact on children – A case study on Baruipur Block, South 24 Parganas, West Bengal -- Effect of Changing Vegetation coverage and Metereological Parameters on the Hazard Characteristics of Indian Sundarban Region and its Impact -- The study of the Impact of Wastewater from Outfall in River Ganga, West Bengal on the Growth and Morphological Parameters of Spinacia Oleracea -- Modeling of Flood Susceptibility and Risk Assessment based on GIS and Analytical hierarchy Process-A Case Study of Adayar River Basin, Tamilnadu, India -- Hydrological Modeling of Om Chhu (River) Basin of Phuentsholing, Bhutan Using SCS-CN Method -- Sustainability, Development and Disaster Risk in Rural Water Supply, Sanitation and Hygiene in Western Nepal -- Sustainable Development through Disaster Risk Management in India: A Case Study of Chandigarh -- Integrated Strategic Environmental Assessment: Nepal’s Earthquake Reconstruction & Sustainable Development Approach Addressing Environment and Disaster Risk -- Disaster resilient and sustainable development in Nepal (issues, challenges, opportunities, an experience of sharing of Himalayan country, Nepal) -- Sustainable Development Through Public Private Partnership: An Approach to Eco-Tourism Hedging Risk to Disaster with Resilience -- Forest and disaster management: a view on North-East India -- Exploring the link between the role of power and procurement and supply chain management systems performance: A case study of International Non-Governmental Organization -- Manipulating Food Preferences for Promoting Sustainability and Reducing Disaster Risk -- Socioeconomic vulnerability assessment: A Case Study of Flood Prone Urban Communities of Pakistan -- Risk Governance and Informal Sector in Disaster Recovery: Case of 2015 Nepal Earthquake -- Cottage and Small Industries in Kathmandu District in the Aftermath of Nepal Earthquake: Preparedness and Lessons Learned. .
    Abstract: This book includes selected papers presented at the international expert forum on “Mainstreaming Resilience and Disaster Risk Reduction in Education,” held at the Asian Institute of Technology, Thailand on 1–2 December 2017. The journey towards disaster risk reduction and resilience requires the participation of a wide array of stakeholders ranging from academics to policymakers, to disaster managers. Given the multifaceted and interdependent nature of disasters, disaster risk reduction and resilience require a multidisciplinary problem-solving approach and evidence-based techniques from the natural, social, engineering, and other relevant sciences. Traditionally, hazard and disaster-related studies have been dominated by the engineering and social science fields. In this regard, the main purpose of this book is to capture the multidisciplinary and multisectoral nature of disaster risk reduction, and to gather existing data, research, conceptual work, and practical cases regarding risk reduction and its ties to sustainable development under a single “umbrella.” Along with the sustainability aspect, the book also links disaster risk reduction with development, technology, governance, education, and climate change, and includes discussions on challenges, solutions, and best practices in the mainstreaming of disaster risk reduction.
    Type of Medium: Online Resource
    Pages: XII, 535 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813295278
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    DDC: 551
    Language: English
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  • 66
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Natural disasters. ; Climatology. ; Physical geography. ; Water. ; Hydrology. ; Environmental Law. ; Human rights. ; Natural Hazards. ; Climate Sciences. ; Earth System Sciences. ; Water. ; Environmental Law. ; Human Rights.
    Description / Table of Contents: Chapter1. Introduction to the Book: “Ahead of the Curve” -- Part1: Louisiana’s Risks Anticipating the Future Challenges to Other U.S. Coastal Communities -- Chapter2. Managing Risks in Louisiana’s Rapidly Changing Coastal Zone -- Part2: Climate Adaptation Challenges and Solutions -- Chapter3. Connecting the Dots: The Origins, Evolutions and Implications of the Land Use -- Chapter4. Antagonisms of Adaptation: Climate Adaptation Measures in New Orleans and New York City -- Chapter5. Adapting to a Smaller Coast: Restoration, Protection, and Social Justice in Coastal Louisiana -- Part3: Relocation and Resettlement -An Extreme Adjustment -- Chapter6. Community Resettlement in Louisiana: Learning from Histories of Horror and Hope -- Chapter6. Sojourners in a New Land: Hope and Adaptive Traditions -- Part4: Types/Locations of Communities and Their Responses to Extreme Weather -- Chapter8. Urban - Post-Disaster Development Dilemmas: Advancing Landscapes of Social Justice in a Neoliberal Post-Disaster Landscape -- Chapter9. Re-Imagining Housing: Affordability Crisis and its Role in Disaster Resilience and Recovery -- Chapter10. Suburban/Mid State- The 2016 Unexpected Mid-State Louisiana Flood: With Special Focus on the Different Rescue and Recovery Responses It Engendered -- Chapter11. Rural- Challenges of Post-Disaster Resilient Recovery in Rural Areas -- Chapter12. Coupled Coastal-Inland - Regional Resilience: Building Adaptive Capacity and Community Wellbeing Across Louisiana’s Dynamic Coastal-Inland Continuum.
    Abstract: This book is open access under a CC BY 4.0 license. This book takes an in-depth look at Louisiana as a state which is ahead of the curve in terms of extreme weather events, both in frequency and magnitude, and in its responses to these challenges including recovery and enhancement of resiliency. Louisiana faced a major tropical catastrophe in the 21st century, and experiences the fastest rising sea level. Weather specialists, including those concentrating on sea level rise acknowledge that what the state of Louisiana experiences is likely to happen to many more, and not necessarily restricted to coastal states. This book asks and attempts to answer what Louisiana public officials, scientists/engineers, and those from outside of the state who have been called in to help, have done to achieve resilient recovery. How well have these efforts fared to achieve their goals? What might these efforts offer as lessons for those states that will be likely to experience enhanced extreme weather? Can the challenges of inequality be truly addressed in recovery and resilience? How can the study of the Louisiana response as a case be blended with findings from later disasters such as New York/New Jersey (Hurricane Sandy) and more recent ones to improve understanding as well as best adaptation applications – federal, state and local?
    Type of Medium: Online Resource
    Pages: XIV, 361 p. 38 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030272050
    Series Statement: Extreme Weather and Society,
    DDC: 551
    Language: English
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