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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geology. ; Tourism. ; Management. ; Geomorphology. ; Environmental geography. ; Geography. ; Geology. ; Tourism Management. ; Geomorphology. ; Integrated Geography. ; Regional Geography.
    Description / Table of Contents: Part I. Introduction and setting the scene. Chapter 1. Geotourism – A Global Overview -- Chapter 2. The Geotourism Potential of Sand and Dunes – From Theory To Practice -- Chapter 3. The Significance of Geotourism Through the Lens Of Geoethics -- Chapter 4. Geotourism in The Middle East- An Overview -- Part II. Country case studies -- Chapter 5. Geotourism in Egypt -- Chapter 6. Geotourism in Iran, A Review -- Chapter 7. Residents’ Perceptions of Geotourism in Qeshm Island UNESCO Global Geopark, Iran -- Chapter 8. Geotourism in Iraq – With Reference to Potential Geoheritage and Geoparks -- Chapter 9. Geotourism in Jordan: The Potential for Developing Geotrails in The Wadis -- Chapter 10. Geotourism In The Sultanate Of Oman – With a Focus on Samail Ophiolite Geosites -- Chapter 11. Geotourism in Qatar -- Chapter 12. Geotourism in Yemen -- Chapter 13. Geotourism in Saudi Arabia -- Chapter 14. Geotourism in Türkiye – Cave Assessment Using Geographical Information Systems -- Chapter 15. Geotourism in Palestine -- Chapter 16. Geotourism in the United Arab Emirates -- Part III. Conclusion. Chapter 17. Conclusion - The Future of Geotourism in The Middle East.
    Abstract: The geotourism industry has grown rapidly in recent years. This book introduces the geotourism industry, its attractions, activities and developments, in selected countries of the Middle East. A number of publications and studies have investigated the nature and scope of the phenomenon of geotourism (tourism which starts from geology) and geotourists worldwide. However, despite the breadth of these studies, few publications have investigated the phenomena in the Middle Eastern countries. Consequently, this book seeks to shed light on the different aspects of geotourism and geo-diversity in the Middle East and provides a number of case studies from this region. It assists in bridging the lacuna in the tourism and geology literature and helps planners, marketers, managers, scholars and researchers to enhance their knowledge about such issues. It outlines opportunities for, as well as barriers to, geotourism development in the Middle East as well as providing recommendations for the advancement of geotourism in the region.
    Type of Medium: Online Resource
    Pages: XV, 278 p. 240 illus., 232 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031241703
    Series Statement: Geoheritage, Geoparks and Geotourism, Conservation and Management Series,
    DDC: 551
    Language: English
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  • 2
    Monograph available for loan
    Monograph available for loan
    Amsterdam [u.a.] : Elsevier
    Call number: PIK N 123-12-0133
    Description / Table of Contents: Contents: Introduction; Cartesian Tensors and Tensor Notation; Kinematics; Conservation Laws; Vorticity Dynamics; Ideal Flow; Gravity Waves; Laminar Flow; Boundary Layers and Related Topics; Computational Fluid Dynamics; Instability; Turbulence; Geophysical Fluid Dynamics; Aerodynamics; Compressible Flow; Introduction to Biofluid Mechanics; Nomenclature; App. A Conversion Factors, Constants, Fluid Properties; App. B Mathematical Tools and Resources; App. C Founders of Modern Fluid Dynamics; App. D Visual Resources; Index
    Type of Medium: Monograph available for loan
    Pages: XXVI, 891 S. : Ill., graph. Darst. + 1 DVD
    Edition: 5. ed.
    ISBN: 9780123821003
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 3
    Publication Date: 2020-11-05
    Description: Acute myeloid leukaemia is a disease of the haematopoietic stem and progenitor cells distinguished by an impairment of proliferation, propagation and differentiation of the haematopoietic lineage[1]. AML is a heterogenous disease, where patient stratification and personalised therapeutic strategies are of importance[2]. The transmembrane protein CD37 has been associated with regulation of cell to cell interaction and proliferation in both B and T cells. Mice knockout studies have suggested that CD37 is not crucial for B cell development, however, it is highly expressed in malignant and suboptimal conditions and thus represent a good target for B-cell malignancies[3]. Pereira et al. reported that their anti-CD37 antibody-drug conjugate was a potential therapeutic in AML[4]. Their study revealed anti-leukemic effect in primary AML material and cell lines bothin vivoandin vitro. An investigation of CD37 expression in AML patients is needed to understand the relevance of CD37 immunotherapy. To investigate the relevance of targeted therapy of CD37 the chimeric mAb NNV003 anti-CD37 antibody was evaluated in AML samples. Single-cell time-of-flight mass cytometry (CyTOF), an established tool to analyse the immune signalling in bone marrow and peripheral blood, was used to investigate CD37 expression in 59 AML patient samples. A panel was designed to categorise hierarchical landscape of AML and the leukemic stem cell population (LSCs). CyTOF identified CD37 expression exclusively in the B-cell population of our 59 patients, whereas the AML blast population was negative for CD37 expression. Flow cytometry, however; identified 5/59 patients with CD37 expression in the leukemic blast population. Although previous studies show that an anti-CD37 drug conjugate showed anti-leukemic effectin vivoandin vitro, our results do not support that it is a promising therapeutic biomarker. We have uncovered that malignant expression of CD37 is not a feature of the AML patients investigated. We do not consider CD37 to be a promising and good target for precision therapy of AML. Kayser, S. and M.J. Levis, Advances in targeted therapy for acute myeloid leukaemia. Br J Haematol, 2018. 180(4): p. 484-500.Patel, J.P., et al., Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. N Engl J Med, 2012. 366(12): p. 1079-89.Payandeh, Z., et al., Anti-CD37 targeted immunotherapy of B-Cell malignancies. Biotechnol Lett, 2018. 40(11-12): p. 1459-1466.Pereira, D.S., et al., AGS67E, an Anti-CD37 Monomethyl Auristatin E Antibody-Drug Conjugate as a Potential Therapeutic for B/T-Cell Malignancies and AML: A New Role for CD37 in AML. Mol Cancer Ther, 2015. 14(7): p. 1650-60. Disclosures Heyerdahl: Nordic Nanovector ASA:Current Employment, Current equity holder in publicly-traded company.Dahle:Nordic Nanovector ASA:Current Employment, Current equity holder in publicly-traded company.Gjertsen:Novartis:Consultancy;KinN Therapeutics AS:Current equity holder in private company;Pfizer Inc:Consultancy;BerGenBio AS:Consultancy, Research Funding;Alden Cancer Therapy AS:Current equity holder in private company.Mccormack:KinN Therapeutics AS:Current equity holder in private company.
    Print ISSN: 0006-4971
    Electronic ISSN: 1528-0020
    Topics: Biology , Medicine
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  • 4
    Publication Date: 2021-05-30
    Description: The PRISMA satellite mission launched on March 22nd, 2019 is one of the latest spaceborne imaging spectroscopy mission for Earth Observation. The PRISMA satellite comprises a high-spectral resolution VNIR-SWIR imaging spectrometer and a panchromatic camera. In summer 2019, first operations during the commissioning phase were mainly devoted to acquisitions in specific areas for evaluating instrument functioning, in-flight performance, and mission data product accuracy. A field and airborne campaign was carried out over an agriculture area in Italy to collect in-situ multi-source spectroscopy measurements at different scales simultaneously with PRISMA. The spectral, radiometric and spatial performance of PRISMA Level 1 Top-Of-Atmosphere radiance (LTOA) product were analyzed. The in-situ surface reflectance measurements over different landcovers were propagated to LTOA using MODTRAN5 radiative transfer simulations and compared with satellite observations. Overall, this work offers a first quantitative evaluation about the PRISMA mission performance and imaging spectroscopy LTOA data product consistency. Our results show that the spectral smile is less than 5 nm, the average spectral resolution is 13 nm and 11 nm (VNIR and SWIR respectively) and it varies ±2 nm across track. The radiometric comparison between PRISMA and field/airborne spectroscopy shows a difference lower than 5% for NIR and SWIR, whereas it is included in the 2–7% range in the VIS. The estimated instrument signal to noise ratio (SNR) is ≈400–500 in the NIR and part of the SWIR (〈1300 nm), lower SNR values were found at shorter (〈700 nm) and longer wavelengths (〉1600 nm). The VNIR-to-SWIR spatial co-registration error is below 8 m and the spatial resolution is 37.11 m and 38.38 m for VNIR and SWIR respectively. The results are in-line with the expectations and mission requirements and indicate that acquired images are suitable for further scientific applications. However, this first assessment is based on data from a rural area and this cannot be fully exhaustive. Further studies are needed to confirm the performance for other land cover types like snow, inland and coastal waters, deserts or urban areas.
    Type: info:eu-repo/semantics/article
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 21 (1982), S. 4088-4095 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 23 (1984), S. 865-869 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 4 (1956), S. 546-548 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 13 (1965), S. 284-287 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 27 (1988), S. 3526-3529 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 16 (1968), S. 108-112 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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