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  • 1
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 59 (1996), S. 719-723 
    ISSN: 0021-8995
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: The article presents a new idea of the application of polymer track membranes (PTM) for immobilization of a reagent in fiber optic chemical sensors. PTM was made of a poly(ethylene terephthalate) foil (10 μm in thickness, pores of 0.2 μm in diameter). The usefulness of membranes additionally covered by poly(vinyl chloride) was tested in a fiber optic redox titrator. The titrator utilized N,N′-diphenylbenzidine as a reagent which changes its absorbance in dependence on the redox potential. The measuring system is based on a lightemitting diode and a silicon photodiode connected to a bifurcated fiber optic bundle. The gain is in price and availability of the membrane. © 1996 John Wiley & Sons, Inc.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Macromolecular Chemistry and Physics 199 (1998), S. 2601-2608 
    ISSN: 1022-1352
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Notizen: N-(2-Hydroxypropyl)methacrylamide (HPMA) copolymer-lectin conjugates were investigated for potential use as targeted oral drug carriers for treatment of inflammatory conditions such as colitis. Wheat germ agglutinin (WGA)-HPMA copolymer and peanut agglutinin (PNA)-HPMA copolymer and fluorescein isothiocyanate (FITC)-labeled WGA- and PNA-HPMA copolymer conjugates were synthesized. Conjugate dissociation constants (Kd) for lectin-carbohydrate binding determined by frontal affinity chromatography indicated that no activity reduction of the lectins occurred during the synthesis of these conjugates. Kd values measured were in good agreement with literature findings for similar lectin-carbohydrate interactions, on the order of 10-5 M-1. Biorecognition of these conjugates by healthy rat intestinal tissue resulted in differential HPMA copolymer-lectin conjugate binding patterns in the same tissue. HPMA copolymer-WGA conjugate showed strong binding in the healthy rat intestinal tissues, while the HPMA copolymer-PNA conjugate showed minimal, but specific binding. This differential binding suggests that site-specific drug delivery via specific lectin recognition may be feasible for treatment of colon inflammation or cancer.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Electroanalysis 8 (1996), S. 75-78 
    ISSN: 1040-0397
    Schlagwort(e): Potentiometry ; Anions ; Calix[4]arene ; Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Anion selectivities of membranes based on cationic complexes of thioamide calix[4]arene derivatives are presented for the first time. HgII complexes of thioamide derivatives of calix[4]arene were applied to design perchlorate-selective ISEs which show linear responses in the range 1-5 of pClO4 with a slope of 56.5mV decade -1. The highest selectivity over other anions (except iodides) and optimum performances of electrodes were obtained for a 0.01 M solution of HgII as an internal electrolyte.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
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