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  • 1
    Digitale Medien
    Digitale Medien
    The application of a wedge perfusion technique to the in vivo-in vitro rat hepatocyte DNA-repair assay
    Amsterdam : Elsevier
    Mutation Research/Environmental Mutagenesis and Related Subjects 252 (1991), S. 129-137 
    Details
    ISSN: 0165-1161
    Schlagwort(e): 2-Acetylaminofluorene ; DNA-repair assay ; Hepatocytes, rat ; Methyl methanesulphonate ; UDS ; Wedge-perfusion technique
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Medizin
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0165-1161(91)90013-X
    Standort Signatur Erwartet Verfügbarkeit
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    Artikel (Nationallizenzen)
    Volltext
  • 2
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    Unbekannt
    Microbial response to space environment, part B (1972)
    In:  CASI
    Details
    Publikationsdatum: 2005-11-30
    Beschreibung: The performance of the microbial response to space environment experiment is considered excellent by all investigators. For most microbial systems, only preliminary survival data are available at this time. None of the available data indicate space flight-mediated changes in cell viability or recovery. One quite important observation has been made at this early date, however. The eggs produced after mice had been infected with N. dubius larvae demonstrated a significant decrease in hatchability when compared to identical ground controls. Except for the fact that the Apollo 16 flight larvae had been on board the command module, treatment of the flown larvae and ground control larvae was the same; neither had been exposed to UV irradiation. The significance and implications of this finding are currently being studied.
    Schlagwort(e): BIOSCIENCES
    Materialart: Apollo 16 Prelim. Sci. Rept.; 6 p
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
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    NASA TECHNICAL REPORTS
  • 3
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    Unbekannt
    Effect of solar irradiation on extracellular enzymes of Aeromonas proteolytica (1973)
    In:  CASI
    Details
    Publikationsdatum: 2006-04-26
    Beschreibung: The bacterium Aeromonas proteolytica was selected for studying the effects of solar irradiation on extracellular enzymes because it produces an endopeptidase that is capable of degrading proteins and a hemolysin that is active in lysing human erythrocytes. Possible alterations in the rate of enzyme production in response to the test conditions are currently underway and are not available for this preliminary report. Completed viability studies are indicative that little difference exists among the survival curves derived for cells exposed to various components of ultraviolet irradiation in space.
    Schlagwort(e): BIOSCIENCES
    Materialart: NASA. Johnson Space Center Proc. of the Microbial Response to Space Environ. Symp.; p 137-151
    Format: text
    Standort Signatur Erwartet Verfügbarkeit
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    NASA TECHNICAL REPORTS
  • 4
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    Unbekannt
    The effects of spacecraft environments on some hydrolytic enzyme patterns in bacteria (1971)
    In:  CASI
    Details
    Publikationsdatum: 2019-06-27
    Beschreibung: The effects of space flight on the production and characteristics of proteolytic enzymes are studied for a number of bacterial species isolated from crew members and spacecraft. Enzymatic make-up and cultural characteristics of bacteria isolated from spacecraft crew members are determined. The organism Aeromonas proteolytica and the proteolytic enzymes which it produces are used as models for future spacecraft experiments.
    Schlagwort(e): BIOSCIENCES
    Materialart: NASA-CR-125805
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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    NASA TECHNICAL REPORTS
  • 5
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    The effect of continuous low dose-rate gamma irradiation on cell population kinetics of lymphoid tissue (1974)
    In:  CASI
    Details
    Publikationsdatum: 2019-06-27
    Beschreibung: Cellular response and cell population kinetics were studied during lymphopoiesis in the thymus of the mouse under continuous gamma irradiation using autoradiographic techniques and specific labeling with tritiated thymidine. On the basis of tissue weights, it is concluded that the response of both the thymus and spleen to continuous low dose-rate irradiation is multiphasic. That is, alternating periods of steady state growth, followed by collapse, which in turn is followed by another period of homeostasis. Since there are two populations of lymphocytes - short lived and long-lived, it may be that different phases of steady state growth are mediated by different lymphocytes. The spleen is affected to a greater extent with shorter periods of steady-state growth than exhibited by the thymus.
    Schlagwort(e): BIOSCIENCES
    Materialart: NASA-CR-140114
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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    NASA TECHNICAL REPORTS
  • 6
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    Aeromonas proteolyrica bacteria in aerospace environments (1974)
    In:  CASI
    Details
    Publikationsdatum: 2019-06-27
    Beschreibung: Preflight studies on Aeromonas proteolytica are reported to investigate the possibility of genetic alterations resulting in increased proteolysis in spacecraft environments. This organism may be present on human tissue and could pose medical problems if its endopeptidase and a hemolysin were to be produced in ususually high quantities or altered in such a way as to be more effective in their activities. Considered are: (1) Development of a nutrative holding medium for suspension of organisms; (2) the establishment of baseline information for the standardization of the assay for endopeptidase levels and hemolytic titers; (3) formulation of a method by which intracutaneous hemorrhage could be quantitated in guinea pig tissue; and (4) the responses of these organisms to parameters of spaceflight and experimentation.
    Schlagwort(e): BIOSCIENCES
    Materialart: NASA-CR-134328
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
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    The effect of continuous low dose-rate gamma irradiation on cell population kinetics of lymphoid tissue (1973)
    In:  CASI
    Details
    Publikationsdatum: 2019-06-27
    Beschreibung: The problem studied involved cell proliferation in mice thymus undergoing irradiation at a dose rate of 10 roetgens/day for 105 days. Specifically, the aim was to determine wheather or not a steady state of cell population can be established for the indicated period of time and what compensatory mechanisms of cell population are involved.
    Schlagwort(e): BIOSCIENCES
    Materialart: NASA-CR-135723 , SASR-4
    Format: application/pdf
    Standort Signatur Erwartet Verfügbarkeit
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