ISSN:
1432-1041
Schlagwort(e):
paracetamol
;
suppository
;
tablets
;
bioavailability
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
,
Medizin
Notizen:
Summary The relative bioavailability of a new paracetamol suppository (Panodil) and tablets in doses of 0.5 and 1 g was investigated in eight healthy subjects. The tablets were absorbed faster and higher peak plasma concentrations were obtained than after the suppositories. The bioavailability of the suppositories was approximately 80% of that of the tablets at both dose levels. There was no indication of capacity-limited elimination at either the two doses investigated.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00570165
Permalink