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  • 1
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-11
    Beschreibung: Laser welding is a high-energy process used in a wide range of advanced materials to obtain micro- to macro-sized joints in both similar and dissimilar combinations. Moreover, this technique is widely used in several industries, such as automotive, aerospace, and medical industries, as well as in electrical devices. Although laser welding has been used for several decades, significant and exciting innovations often arise from both the process and/or advanced materials side.
    Schlagwort(e): TA1-2040 ; T1-995 ; n/a ; tensile strength ; microstructure ; aided electric current ; stainless steel ; accuracy ; porosity control ; laser offset welding ; T-joint ; BTi-6431S ; dissimilar metal ; finite element method ; weld pool behavior ; dissimilar welding ; WPP ; laser welds ; HLAW ; fiber laser ; steel S700MC ; conduction regime ; liquid metal ; buy-to-fly ; EBSD phase mapping ; mass transfer ; mechanical properties ; hardness ; MAG ; phase transformation ; prediction ; LKW ; Ti-5Al-5V-5Mo-3Cr ; laser beam ; laser welding-brazing ; DP1000 steel ; Ti–6Al–4V ; titanium ; low alloyed steel ; H-shaped fusion zone ; pulsed Nd:YAG laser beam welding ; spatter ; high-speed imaging ; weld morphology ; high temperature titanium alloy ; Al/steel joints ; hybrid welding ; dissimilar material ; laser beam welding ; intermetallic layer ; WW ; L-joint ; penetration ; laser stake welding ; laser keyhole welding ; trip steel ; finite element analysis ; laser welding ; magnesium alloy thin sheet ; keyhole ; tensile properties ; dissimilar joining ; IMC layers ; SKM ; fiber laser welding ; aluminium ; dual phase steel ; aluminum alloy T-joint ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Publikationsdatum: 2023-12-21
    Beschreibung: The immunological synapse (IS) is a specialised cell-cell adhesion that mediates antigen acquisition and regulates the activation of lymphocytes. Initial studies of the IS showed a structure composed of stable supra-molecular activation clusters (SMAC) organised during the interaction of helper T lymphocytes with B lymphocytes, working as antigen presenting cells. A central SMAC of coalesced T cell receptors (TCRs) and a peripheral SMAC for cell-cell adhesion were observed. IS with similar structure was later described during antigen acquisition by B cells and during the interaction of NK cells with target and healthy cells. More recent research developed with microscopy systems that improve the spatial and temporal resolution has showed the complex molecular dynamics at the IS that governs lymphocyte activation. Currently, the IS is seen as a three-dimensional structure where signalling networks for lymphocyte activation and endosomal and cytoskeleton machinery are polarised. A view has emerged in which dynamic microclusters of signalling complexes are composed of molecular components attached to the plasma membrane and other components conveyed on sub-synaptic vesicles transported to the membrane by cytoskeletal fibers and motor proteins. Much information is nonetheless missing about how the dynamics of the endosomal compartment, the cytoskeleton, and signalling complexes are reciprocally regulated to achieve the function of lymphocytes. Experimental evidence also suggests that the environment surrounding lymphocytes exposed to different antigenic challenge regulates IS assembly and functional output, making an even more complex scenario still far from being completely understood. Also, although some signalling molecular components for lymphocyte activation have been identified and thoroughly studied, the function of other molecules has not been yet uncovered or deeply characterised. This research topic aims to provide the reader with the latest information about the molecular dynamics governing lymphocyte activation. These molecular dynamics dictate cell decisions. Thus, we expect that understanding them will provide new avenues for cell manipulation in therapies to treat different immune-related pathologies.
    Schlagwort(e): R5-920 ; RC581-607 ; cytoskeleton dynamics ; intracellular signalling ; Immunological Synapse ; endosomal dynamics ; bic Book Industry Communication::M Medicine
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Publikationsdatum: 2024-04-01
    Beschreibung: The considerable number of viral infectious disease threats that have emerged since the beginning of the 21st century have shown the need to dispose global and coordinated responses to fight properly and efficiently against them. Severe acute respiratory syndrome (2003), avian influenza in humans (2005), A(H1N1) pandemic influenza (2009), Middle East respiratory syndrome coronavirus (MERS-CoV) (2012 onward) and Ebola virus disease (2014-2015) are some of the most important examples. The latest emerging and devastating threat was Zika virus, an arbovirus that provoked more than 500,000 suspicious cases in the Americas in 2016 and notable processes of social and medical alarms due to the evidence of a causal link between Zika virus and several congenital injuries, like microcephaly, as well as due to its association with neurological disorders such as Guillain-Barré syndrome in adults (PAHO, 2017). In the framework of this global response and multistrategic approach, the purpose of this Research Topic is to provide updated information and novel researches about control strategies, encompassing virological, entomological and epidemiological data, in order to reach the triad of protagonists of transmission cycles (virus, mosquitoes and humans).
    Schlagwort(e): RC346-429 ; R5-920 ; RA1-1270 ; QR1-502 ; Q1-390 ; RC109-216 ; Public Health ; Mosquitoes ; Zika virus ; Arbovirus ; Microcephaly ; Epidemiology ; Flavivirus ; Guillain-Barre Syndrome ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
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    Unbekannt
    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2023-12-21
    Beschreibung: Marine biotoxins may pose a threat to the human consumption of seafood and seafood products. The increasing global trade and higher demand for seafood products worldwide represents a challenge for food safety authorities, policy makers, food business operators, and the scientific community, in particular, researchers devoted to environmental sciences, toxicology, and analytical chemistry. In addition, due to changes in climate conditions and technological developments, new and emerging marine toxins are being detected in regions where they were previously unknown. This Special Issue highlight studies aiming to the develop detection methods for marine biotoxins for better understanding the dynamics of accumulation/elimination of marine biotoxins and their effects on marine organisms, as well as toxin exposure studies that aim to evaluate the risks associated with the consumption of contaminated seafood.
    Schlagwort(e): R5-920 ; RA1190-1270 ; mass mortality ; marine biotoxin ; n/a ; alamethicin ; synergy ; seafood toxin ; patulin ; Paralytic shellfish toxin ; greater blue-ringed octopus ; Alexandrium catenella ; paralytic toxicity ; Ishigaki Island ; depuration ; okadaic acid ; serum biomarker ; ecotoxicological responses ; Hapalochlaena lunulata ; sydowinin A ; purification ; PSP outbreak ; southern Chile ; posterior salivary gland ; saxitoxin ; harmful algal blooms ; gliotoxin ; seafood safety ; uptake ; immunoaffinity column ; Alexandrium ; sydowinol ; chronic exposure ; environmental neurotoxin ; assimilation ; shellfish ; LC-MS ; biotransformation ; Perna viridis ; domoic acid ; fish ; algal toxin ; warming ; tetrodotoxin ; Mesodesma donacium ; combination index ; ultrahigh high performance liquid chromatography tandem mass spectrometry ; bic Book Industry Communication::M Medicine
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-05
    Beschreibung: The development of new plant varieties is a long and tedious process involving the generation of large seedling populations for the selection of the best individuals. While the ability of breeders to generate large populations is almost unlimited, the selection of these seedlings is the main factor limiting the generation of new cultivars. Molecular studies for the development of marker-assisted selection (MAS) strategies are particularly useful when the evaluation of the character is expensive, time-consuming, or with long juvenile periods. The papers published in the Special Issue “Plant Genetics and Molecular Breeding” report highly novel results and testable new models for the integrative analysis of genetic (phenotyping and transmission of agronomic characters), physiology (flowering, ripening, organ development), genomic (DNA regions responsible for the different agronomic characters), transcriptomic (gene expression analysis of the characters), proteomic (proteins and enzymes involved in the expression of the characters), metabolomic (secondary metabolites), and epigenetic (DNA methylation and histone modifications) approaches for the development of new MAS strategies. These molecular approaches together with an increasingly accurate phenotyping will facilitate the breeding of new climate-resilient varieties resistant to abiotic and biotic stress, with suitable productivity and quality, to extend the adaptation and viability of the current varieties.
    Schlagwort(e): QH301-705.5 ; Q1-390 ; n/a ; GA2ox7 ; cabbage ; OsGPAT3 ; oleic acid ; OsCDPK1 ; nutrient use efficiency ; stem borer ; yellow-green-leaf mutant ; branching ; epigenetics ; NPK fertilizers ; particle bombardment ; stress tolerance ; overexpression ; glycine ; heat-stress ; bulk segregant RNA-seq ; Prunus ; protein-protein interaction ; AdRAP2.3 ; plant architecture ; waterlogging stress ; genes ; Cucumis sativus L. ; Flower color ; resistance ; Tobacco ; gynomonoecy ; drought stress ; Brassica oleracea ; starch biosynthesis ; Overexpression ; WUS ; agronomic traits ; Ghd7 ; the modified MutMap method ; cry2A gene ; light-induced ; gene expression ; breeding ; Heterodera schachtii ; ABA ; Green tissue-specific expression ; subcellular localization ; squamosa promoter binding protein-like ; transcriptome ; FAD2 ; As3+ stress ; metallothionein ; flowering ; bisulfite sequencing ; tomato ; quantitative trait loci ; Promoter ; marker–trait association ; DEGs ; cytoplasmic male sterile ; Rosa rugosa ; MADS transcription factor ; yield ; P. suffruticosa ; CYC2 ; common wild rice ; Actinidia deliciosa ; gene-by-gene interaction ; Aechmea fasciata ; hybrid rice ; soybean ; R2R3-MYB ; bread wheat ; BRANCHED1 (BRC1) ; linoleic acid ; differentially expressed genes ; complex traits ; transgenic chrysanthemum ; D-genome ; Brassica ; candidate gene ; SmJMT ; gene expression pattern ; RNA-Seq ; candidate genes ; leaf shape ; Brassica napus ; recombination-suppressed region ; anthocyanin ; WRKY transcription factor ; Idesia polycarpa var ; single nucleotide polymorphism ; bud abortion ; QTL ; reproductive organ ; transient overexpression ; Elongated Internode (EI) ; sugarcane ; abiotic stress ; Oryza sativa L. ; RrGT2 gene ; Hd1 ; cZR3 ; cytoplasmic male sterility (CMS) ; seed development ; tapetum ; near-isogenic line (NIL) ; phytohormones ; TCP transcription factor ; pollen accumulation ; Anthocyanin ; WRKY ; quantitative trait loci (QTLs) ; salt stress ; floral scent ; sucrose ; Ogura-CMS ; root traits ; endosperm development ; Zea mays L. ; sesame ; Bryum argenteum ; AP2/ERF genes ; transcriptional regulation ; WB1 ; haplotype block ; broccoli ; agronomic efficiency ; durum wheat ; gene pyramiding ; Oryza sativa ; genetics ; flowering time ; Cicer arietinum ; Hs1pro-1 ; endosperm appearance ; phenolic acids ; anther wall ; bromeliad ; genomics ; transgenic ; DgWRKY2 ; Clone ; yield trait ; flower symmetry ; partial factor productivity ; rice ; molecular breeding ; genotyping-by-sequencing ; Chimonanthus praecox ; nectary ; Salvia miltiorrhiza ; pollen development ; regulation ; ZmES22 ; genome-wide association study ; VIGS ; iTRAQ ; genome-wide association study (GWAS) ; ethylene-responsive factor ; starch ; molecular markers ; rice quality ; Chrysanthemum morifolium ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Sprache: Englisch
    Format: image/jpeg
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publikationsdatum: 2024-04-11
    Beschreibung: The Special Issue Distributed Energy Resources Management 2018 includes 13 papers, and is a continuation of the Special Issue Distributed Energy Resources Management. The success of the previous edition shows the unquestionable relevance of distributed energy resources in the operation of power and energy systems at both the distribution level and at the wider power system level. Improving the management of distributed energy resources makes it possible to accommodate the higher penetration of intermittent distributed generation and electric vehicle charging. Demand response programs, namely the ones with a distributed nature, allow the consumers to contribute to the increased system efficiency while receiving benefits. This book addresses the management of distributed energy resources, with a focus on methods and techniques to achieve an optimized operation, in order to aggregate the resources namely in the scope of virtual power players and other types of aggregators, and to remunerate them. The integration of distributed resources in electricity markets is also addressed as an enabler for their increased and efficient use.
    Schlagwort(e): TA1-2040 ; T1-995 ; n/a ; virtual power plant ; bidding strategy ; local flexibility market ; multi-period optimal power flow ; flexibility service ; occupant comfort ; unbalanced networks ; decentralized energy management system ; autonomous control ; optimization ; energy storage ; microgrids ; energy efficiency ; distributed energy ; control system ; DSM ; optimal scheduling ; adaptability ; synergistic optimization strategy ; teaching-learning ; distributed generation ; energy storage system ; stackelberg dynamic game ; IoT (Internet of Things) ; supply and demand ; comprehensive benefits ; distributed generator ; frequency bus-signaling ; active distribution networks ; swarm intelligence ; wind ; multi-agent technology ; solar ; power system management ; fault-tolerant control ; indoor environment quality ; multi-temporal optimal power flow ; multi-agent synergetic estimation ; smart grids ; local energy trading ; active power control ; prosumer ; microgrid ; trade agreements ; healthy building ; smart grid ; nonlinear control ; algorithm design and analysis ; batteries ; droop control ; distributed energy resources ; aggregator ; multi-agent system ; frequency control ; particle swarm optimization ; distribution system operator ; building climate control ; low voltage networks ; demand Response ; clustering ; distributed coordination ; demand-side management ; demand response ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Sprache: Englisch
    Format: application/octet-stream
    Standort Signatur Erwartet Verfügbarkeit
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