ISSN:
1040-7685
Keywords:
unified chromatography
;
supercritical fluid chromatography
;
gas chromatography
;
open tubular column
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A unified chromatograph was constructed in which open tubular column gas chromatography, at normal helium carrier gas pressures, followed by supercritical fluid chromatography with carbon dioxide mobile phase was carried out in a single run using a 100-μm i. d. column. Sample introduction was accomplished by means of a pneumatically-actuated rotary injection valve. A second rotary valve was used post-column to direct the flow of column effluent to the flame ionization detector through an uncoated fused silica restrictor during the GC separation mode or to the FID through a frit restrictor during the SFC separation mode. This novel valve switching arrangement allowed system operating parameters of temperature and pressure programs and linear velocities to be optimized independently of each separation mode. The unified GC/SFC system was demonstrated for practical applications in various fields of process and product quality control.
Additional Material:
8 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mcs.1220030504
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