ISSN:
0935-6304
Keywords:
Thin-layer chromatography, TLC
;
Mobile phase parameters and RM-value
;
Influence of surface of adsorbed molecules
;
Non-active binary mobile phases
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The purpose of the studies being carried out is to find some regularities of a general character which determine the relationship between the structures of the chromatographed substances and the composition of the mobile phase, i.e., between the log of the partition coefficient of the sample (Az), the K1-values which characterize the adsorption equilibrium of component “1” in a given chromatographic system, the structures of the mobile phase components and the structures of the substances being chromatographed. This paper deals with the relationship between the Az and K1 parameters and the structure of naphthalene and a number of its derivatives. It has been shown that there is a close relationship between the kind, size, frequency and site of the substituent on the one hand and the Az and K1 values on the other. In order to eliminate the possibility of unwanted side effects, the investigations were carried exclusively using non-active binary mobile phases of the type N + N or N + /B/. From these investigations, a comparison between the parameter Az and the surface of adsorbed molecules (As) was also possible.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240030205
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