ISSN:
1432-0983
Keywords:
Key words Saccharomyces cerevisiae
;
UFE1
;
Secretion
;
TMP1
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The UFE1 gene of Saccharomyces cerevisiae was cloned, sequenced and characterized. The coding region of UFE1 is separated from the TMP1 gene on chromosome XV by 624 bp. Gene-disruption experiments demonstrated that UFE1 is essential for both the germination of ascospores and for vegetative growth. Translation of the UFE1 coding region generates a protein with significant similarity to cytokeratin and to the coiled-coil region of SED5, USO1 and restin, suggesting that it is involved in the secretory pathway and may also be related to intermediate filament-associated proteins.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002940050148
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