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  • 1
    Electronic Resource
    Electronic Resource
    Compartmental modelling based on methionine tolerance test data: a case study (1979)
    Springer
    Medical & biological engineering & computing 17 (1979), S. 223-229 
    Details
    ISSN: 1741-0444
    Keywords: Metabolic systems ; Modelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A case study illustrates the application of systems theory to the analysis of data from nonrepeatable experiments with relatively few data points. The specific problem considered is the compartmental modelling in the human of the metabolic pathways of orally-administered methionine using tolerance test data. Attention is restricted to linear models, and concentrates on the determination of parsimonious structures (i.e. with as few parameters as possible) and their physiological interpretation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02440933
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Adequacy of measurements in compartmental modelling of metabolic systems (1979)
    Springer
    Medical & biological engineering & computing 17 (1979), S. 216-222 
    Details
    ISSN: 1741-0444
    Keywords: Metabolic systems ; Modelling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The adequacy of present-day measurement techniques for the compartmental modelling of metabolic systems is investigated using numerical examples and analysis of experimentally-obtained plasma clearance curves. It is concluded that the model parameters obtained are often of questionable accuracy. The situation can be improved by careful monitoring of experimental conditions and judicious spacing of data points on the response curve, but the work shows a clear need for a continuous (or semicontinuous) method of monitoring plasma concentration. To resolve ambiguities between models equally plausible on physiological grounds, it is necessary to monitor the dynamics of internal variables, for example, of the concentration in the liver (which is nowadays possible noninvasively).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02440932
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    Paper (German National Licenses)
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  • 3
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    Ocean gravity and geoid determination (1979)
    In:  Other Sources
    Details
    Publication Date: 2011-08-17
    Description: Gravity anomalies have been recovered in the North Atlantic and the Indian Ocean regions. Comparisons of 63 2 deg x 2 deg mean free air gravity anomalies recovered in the North Atlantic area and 24 5 deg x 5 deg mean free air gravity anomalies in the Indian Ocean area with surface gravimetric measurements have shown agreement to + or - 8 mGal for both solutions. Geoids derived from the altimeter solutions are consistent with altimetric sea surface height data to within the precision of the data, about + or - 2 m.
    Keywords: OCEANOGRAPHY
    Type: Journal of Geophysical Research; 84; July 30
    Format: text
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    NASA TECHNICAL REPORTS
  • 4
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    Mean sea level determination from satellite altimetry (1979)
    In:  Other Sources
    Details
    Publication Date: 2011-08-17
    Description: The primary experiment on the Geodynamics Experimental Ocean Satellite-3 (GEOS-3) is the radar altimeter. This experiment's major objective is to demonstrate the utility of measuring the geometry of the ocean surface; i.e., the geoid. Results obtained from this experiment so far indicate that the planned objectives of measuring the topography of the ocean surface with an absolute accuracy of + or - 5 m can be met and perhaps exceeded. The GEOS-3 satellite altimeter measurements have an instrument precision in the range of + or - 25 cm to + or - 50 cm when the altimeter is operating in the 'short pulse' mode. After one year's operations of the altimeter, data from over 5000 altimeter passes have been collected. With the mathematical models developed and the altimeter data presently available, mapping of local areas of ocean topography has been realized to the planned accuracy levels and better. This paper presents the basic data processing methods employed and some interesting results achieved with the early data. Plots of mean sea surface heights as inferred by the altimeter measurements are compared with a detailed 1 by 1 deg gravimetric geoid.
    Keywords: OCEANOGRAPHY
    Type: Marine Geodesy; 2; 2, 19; 1979
    Format: text
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  • 5
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    Surface observations for the evaluation of geophysical measurements from Seasat (1979)
    In:  Other Sources
    Details
    Publication Date: 2019-06-27
    Description: The surface observations used for direct comparison with Seasat-derived values at fixed locations and as input to analyzed fields of pressure, wind, air and sea temperatures, and surface dew point are discussed. These included measurements made by research vessels participating in the Gulf of Alaska Seasat Experiment (GOASEX) and NOAA research platforms in addition to aircraft observations and reports from the World Weather Watch. The application of these observations in describing the synoptic-scale winds over the ocean is discussed, and the sensitivity of the verification statistics to the type of data (observations from buoys, weather ships, and transient vessels with or without anemometers) is considered. Results of a preliminary comparison of wind fields derived from Seasat-A scatterometer observation with winds specified by several types of platforms are presented.
    Keywords: OCEANOGRAPHY
    Type: Science; 204; June 29
    Format: text
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