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  • Murein (peptidoglycan) synthesis  (1)
  • 1980-1984  (1)
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  • 1980-1984  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 127 (1980), S. 187-193 
    ISSN: 1432-072X
    Keywords: Antibiotics ; Murein (peptidoglycan) synthesis ; Nisin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Nisin inhibits murein synthesis with concomitant accumulation of undecaprenyl-pyrophospho-MurNAc(pentapeptide) (lipid intermediate I). This inhibition is caused by the formation of a complex between the antibiotic and lipid intermediate I. Undecaprenyl-pyrophospho-MurNAc(pentapeptide)-GlcNAc (lipid intermediate II) also forms a complex with nisin. However, when murein synthesis is inhibited by nisin, this latter complex is not formed since lipid intermediate II is no longer synthesized.
    Type of Medium: Electronic Resource
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